Digital Commons Network^™

On A Stationary Random Knot, Andrey A. Dorogovtsev

Journal of Stochastic Analysis

No abstract provided.

Nano-Injection Molding With Resin Mold Inserts For Prototyping Of Nanofluidic Devices For Single Molecular Detection, Farhad Shiri, Junseo Choi, Chad Vietz, Chathurika Rathnayaka, Anishkumar Manoharan, Suresh Shivanka, Guoqiang Li, Chengbin Yu, Michael C. Murphy, Steven A. Soper, Sunggook Park

Faculty Publications

While injection molding is becoming the fabrication modality of choice for high-scale production of microfluidic devices, especially those used for in vitro diagnostics, its translation into the growing area of nanofluidics (structures with at least one dimension <100 >nm) has not been well established. Another prevailing issue with injection molding is the high startup costs and the relatively long time between device iterations making it in many cases impractical for device prototyping. We report, for the first time, functional nanofluidic devices with dimensions of critical structures below 30 nm fabricated by injection molding for the manipulation, identification, and detection of single …

Deciphering The Role Of Molecular Interactions On The Interfacial Structure Of Aqueous And Non-Aqueous Interfaces, Dodangodage Ishara Indunil Senadheera, D I. Senadheera

LSU Doctoral Dissertations

The study focused on "Deciphering the role of molecular interactions on the interfacial structure of aqueous and non-aqueous interfaces" holds immense significance in diverse scientific and industrial domains. Our primary objective is to unravel the intricate web of molecular interactions occurring at the boundaries between aqueous and non-aqueous phases. The research presented here spans a wide scope, encompassing applications in microelectromechanical systems in the semiconductor industry, energy-efficient membranes for electrochemical separations, and renewable energy storage systems. Molecular dynamics simulations were conducted in collaboration with experimental studies, specifically atomic force microscopy, to achieve insights at the molecular level.The first project centered …

France Within Louisiana Law, Government, And Media, Nicolas Garon

Tête à Tête: Journal of Francophone Studies

No abstract provided.

Le Québec Entre Le « Past-Self » Et Le « Possible-Self » Dans La Face Cachée De La Lune, Andisheh Ghaderi

Tête à Tête: Journal of Francophone Studies

No abstract provided.

Entre Ombre Et Lumière : L’Artifice Et La Réflexion Sociétale Dans La Princesse Maleine De Maeterlinck, Anoosheh Ghaderi

Tête à Tête: Journal of Francophone Studies

No abstract provided.

Lrtransformer: Learn-Region Transformer For Object-Agnostic Point Cloud Segmentation, Dipesh Gyawali

LSU Master's Theses

3D point cloud segmentation segments the 3D point cloud data into different regions/instances depending on their features that have numerous applications in robotics, autonomous driving, digital twinning, augmented reality, etc. The majority of the existing point cloud segmentation methods depend on class labels to identify 3D objects in the surroundings. Our work focuses on segmenting point clouds into different regions/instances in an object-agnostic manner for any number of objects in the environment. Given the point cloud, our method can segment the entire scene into multiple instances without depending on object shape and size. We leverage the power of the self-attention …

Cationic Frontal Polymerization: Front Kinetics, Effects Of Additives, And Applications, Brecklyn R. Groce

LSU Doctoral Dissertations

Cationic frontal polymerization broadens the potential application of frontal polymerization by allowing for use of monomers such as epoxies and vinyl ethers. In this work, the effects of monomer and initiator composition and additives including fillers on front kinetics, along with applications of cationic frontal polymerization were investigated.

Using a radical-induced cationic frontal polymerization (RICFP) method with a superacid generating salt and a thermal radical initiator, the addition of vinyl ethers to epoxy formulations was studied, where an increase of front velocity was seen with increase of divinyl ether to epoxy ratio. Other aspects of vinyl ether systems, such as …

Ready Worker One? High-Res Vr For The Home Office, Anastasia Ruvimova, Felipe Fronchetti, Boden A. Kahn, Luiz Henrique Susin, Zekeya Hurley, Thomas Fritz, Mark Hancock, David Shepherd

Faculty Publications

Many employees prefer to work from home, yet struggle to squeeze their office into an already fully-utilized space. Virtual Reality (VR) seemingly offered a solution with its ability to transform even modest physical spaces into spacious, productive virtual offices, but hardware challenges - such as low resolution - have prevented this from becoming a reality. Now that hardware issues are being overcome, we are able to investigate the suitability of VR for daily work. To do so, we (1) studied the physical space that users typically dedicate to home offices and (2) conducted an exploratory study of users working in …

Influences On Participation In The National Flood Insurance Program’S Community Rating System In Coastal Counties In Louisiana, Mississippi, Alabama, And Florida, Jennifer E. Argote

LSU Doctoral Dissertations

The National Flood Insurance Program provides an incentive-based program, the Community Rating System (“CRS”), to encourage communities to improve their hazard mitigation protocols to better protect against and prevent flood-related hazards. This dissertation analyzes factors that influence participation and points scored within the CRS to gain an understanding of the conditions under which communities are willing and able to take advantage of an incentive-based flood hazard mitigation program. It also includes an analysis of survey responses from 41 coastal county floodplain and CRS managers to gauge their opinions on the CRS and how it can be improved to better serve …

Role Of Domain-Domain Interactions On The Self-Association And Physical Stability Of Monoclonal Antibodies: Effect Of Ph And Salt, Amy Y. Xu, Marco A. Blanco, Maria Monica Castellanos, Curtis W. Meuse, Kevin Mattison, Ioannis Karageorgos, Harold W. Hatch, Vincent K. Shen, Joseph E. Curtis

Faculty Publications

Monoclonal antibodies (mAbs) make up a major class of biotherapeutics with a wide range of clinical applications. Their physical stability can be affected by various environmental factors. For instance, an acidic pH can be encountered during different stages of the mAb manufacturing process, including purification and storage. Therefore, understanding the behavior of flexible mAb molecules in acidic solution environments will benefit the development of stable mAb products. This study used small-angle X-ray scattering (SAXS) and complementary biophysical characterization techniques to investigate the conformational flexibility and protein-protein interactions (PPI) of a model mAb molecule under near-neutral and acidic conditions. The study …

Noise In The Ligo Livingston Gravitational Wave Observatory Due To Trains, J. Glanzer, S. Soni, J. Spoon, A. Effler, G. González

Faculty Publications

Environmental seismic disturbances limit the sensitivity of LIGO gravitational wave detectors. Trains near the LIGO Livingston detector produce low frequency (0.5- 10 H z ) ground noise that couples into the gravitational wave sensitive frequency band (10- 100 H z ) through light reflected in mirrors and other surfaces. We investigate the effect of trains during the Advanced LIGO third observing run, and propose a method to search for narrow band seismic frequencies responsible for contributing to increases in scattered light. Through the use of the linear regression tool Lasso (least absolute shrinkage and selection operator) and glitch correlations, we …

Backward Stochastic Differential Equations In A Semi-Markov Chain Model, Robert J. Elliott, Zhe Yang

Journal of Stochastic Analysis

No abstract provided.

Regional Variation In The Trophic Ecology Of Wahoo (Acanthocybium Solandri) In The Western Atlantic Ocean, Brendan Gough, Alexandra Prouse, Michael A. Dance, R. J.David Wells, Jay R. Rooker

Faculty Publications

Intrinsic tracers, such as stable isotopes of carbon and nitrogen, are common dietary markers that accumulate in the muscle tissue of consumers and can be used to determine the dietary sources and trophic positions of consumers. The aim of this study was to assess regional variation in the trophic ecology of wahoo (Acanthocybium solandri) using bulk stable isotopes. Muscle biopsies of wahoo were collected from four regions in the western Atlantic Ocean: the eastern Gulf of Mexico, western Gulf of Mexico, Northwest Atlantic Ocean, and Caribbean Sea. Muscle tissue δ¹³C and δ¹⁵N values for wahoo ranged …

Journey Of A Thousand Miles: From Manpo-Kei' To The First Steps-Based Physical Activity Recommendations, Emmanuel Stamatakis, Matthew Ahmadi, Marie H. Murphy, Timothy James Chico, Karen Milton, Borja Del Pozo Cruz, Peter T. Katzmarzyk, I. Min Lee, Jason Gill

Population and Public Health Science Faculty Publications

No abstract provided.

White Adipose Tissue Heterogeneity In The Single-Cell Era: From Mice And Humans To Cattle, Hunter Ford, Qianglin Liu, Xing Fu, Clarissa Strieder-Barboza

Faculty Publications

Adipose tissue is a major modulator of metabolic function by regulating energy storage and by acting as an endocrine organ through the secretion of adipokines. With the advantage of next-generation sequencing-based single-cell technologies, adipose tissue has been studied at single-cell resolution, thus providing unbiased insight into its molecular composition. Recent single-cell RNA sequencing studies in human and mouse models have dissected the transcriptional cellular heterogeneity of subcutaneous (SAT), visceral (VAT), and intramuscular (IMAT) white adipose tissue depots and revealed unique populations of adipose tissue progenitor cells, mature adipocytes, immune cell, vascular cells, and mesothelial cells that play direct roles on …

A Single-Cell Atlas Of Bovine Skeletal Muscle Reveals Mechanisms Regulating Intramuscular Adipogenesis And Fibrogenesis, Leshan Wang, Peidong Gao, Chaoyang Li, Qianglin Liu, Zeyang Yao, Yuxia Li, Xujia Zhang, Jiangwen Sun, Constantine Simintiras, Matthew Welborn, Kenneth Mcmillin, Stephanie Oprescu, Shihuan Kuang, Xing Fu

Faculty Publications

Background: Intramuscular fat (IMF) and intramuscular connective tissue (IMC) are often seen in human myopathies and are central to beef quality. The mechanisms regulating their accumulation remain poorly understood. Here, we explored the possibility of using beef cattle as a novel model for mechanistic studies of intramuscular adipogenesis and fibrogenesis. Methods: Skeletal muscle single-cell RNAseq was performed on three cattle breeds, including Wagyu (high IMF), Brahman (abundant IMC but scarce IMF), and Wagyu/Brahman cross. Sophisticated bioinformatics analyses, including clustering analysis, gene set enrichment analyses, gene regulatory network construction, RNA velocity, pseudotime analysis, and cell–cell communication analysis, were performed to elucidate …

Fall Facts, 2023, Louisiana State University

Fall Facts

No abstract provided.

Fall 2023 Catalog, Lsu Press

LSU Press Seasonal Catalogs

No abstract provided.

Chemical Communication In Insects: New Advances In Integrated Pest Management Strategies, Angel Guerrero, Gadi V.P. Reddy

Faculty Publications

No abstract provided.

Early Season Monitoring Of Tarnished Plant Bug, Lygus Lineolaris, In Wild Hosts Using Pheromone Traps, Justin George, James P. Glover, Gadi V.P. Reddy, Chris Johnson, David R. Hall

Faculty Publications

The tarnished plant bug, Lygus lineolaris (Hemiptera: Miridae), has a wide host range of over 700 plant species, including 130 crops of economic importance. During early spring, managing the field edges with weeds and other wild hosts is important in preventing early-season infestations of L. lineolaris in cotton to prevent damage to the squares and other fruiting structures. Scouting fields for L. lineolaris is time- and labor-intensive, and end-user variability associated with field sampling can lead to inaccuracies. Insect traps that combine visual cues and pheromones are more accurate, sustainable, and economically feasible in contrast to traditional insect detection methods. …

Can A Eutrophic Lake Function As A Carbon Sink? Case Study Of A Subtropical Eutrophic Lake In Southern Usa, Lee Potter, Y. J. Xu

Faculty Publications

Carbon dioxide (CO2) outgassing from inland eutrophic waters is a small but critical component of the global carbon cycle that is currently not well constrained. Eutrophic lake systems have been reported to be supersaturated with dissolved CO2 (pCO2), therefore considered a carbon source to the atmosphere. In this study, we aimed to test two hypotheses: 1) there is a substantial diurnal fluctuation in pCO2 in eutrophic lakes, making them both a source and a sink of carbon; and 2) the diurnal fluctuation is seasonally dependent, with a pronounced variability during the summer. As a case study, we used a hypereutrophic …

Message Or Messenger? Source And Labeling Effects In Authoritarian Response To Protest, Daniel Arnon, Pearce Edwards, Handi Li

Faculty Publications

Authoritarian regimes in the 21st century have increasingly turned to using information control rather than kinetic force to respond to threats to their rule. This paper studies an often overlooked type of information control: strategic labeling and public statements by regime sources in response to protests. Labeling protesters as violent criminals may increase support for repression by signaling that protests are illegitimate and deviant. Regime sources, compared to more independent sources, could increase support for repression even more when paired with such an accusatory label. Accommodative labels should have opposing effects—decreasing support for repression. The argument is tested with a …

Examination Of Real-Time Variation In Interpersonal Hopelessness And Suicidal Desire In A College Student Sample Reporting Past-2-Week Suicidal Ideation, Jessica L. Gerner, Emma H. Moscardini, Sean M. Mitchell, Ryan M. Hill, Raymond P. Tucker

Faculty Publications

Introduction: Interpersonal hopelessness (IH), as outlined in the Interpersonal Theory of Suicide, is theorized to include two correlated, distinct constructs: hopelessness about one's thwarted belongingness (IH-TB) and about perceived burdensomeness on others (IH-PB). Few studies have explored IH, and none have explored its temporal stability or prospective prediction of suicidal desire. Methods: Undergraduates (N = 43) selectively recruited for past-2-week suicidal ideation completed five ecological momentary assessment surveys per day for 10-days. Intraclass correlations, root mean square of successive differences, and multilevel models were used to examine the data and test relationships among predictor variables. Results: IH-TB and IH-PB demonstrated …

"Weight Loss Is My Goal And Being Healthy Is My Goal. I Can Get Over The Hot Flashes": A Qualitative Exploration Of Menopausal Transition Experiences And Preferences For Weight Management Among White Women, Chelsea L. Kracht, Jessica St. Romain, Julie C. Hardee, Nanette Santoro, Leanne M. Redman, Kara L. Marlatt

Clinical Research Faculty Publications

Objectives A qualitative research study design was used to (1) describe experiences of White women during the menopausal transition, and (2) identify barriers and facilitators for participating in a lifestyle program targeting weight management. Methods Perimenopausal and postmenopausal White women who self-reported a desire to lose or maintain weight participated in focus groups. Women were queried about their past diet, exercise, and weight management practices; menopausal transition; and specific components and considerations for developing a lifestyle program for weight management. Thematic analysis was conducted on coded transcripts and four main themes emerged, each containing three to six subthemes. Results Twenty-eight …

Relational Sanctification, Communal Coping, And Depression Among African American Couples, Antonius D. Skipper, Andrew H. Rose, Noel A. Card, Travis James Moore, Debra Lavender-Bratcher, Cassandra Chaney

Faculty Publications

Despite the common use of religious buffers, African Americans are disproportionately affected by depressive symptoms. Communal coping may serve as one factor in helping religious African American couples alleviate the symptoms of depression. This study examines the association between relational sanctification and depressive symptoms as mediated by the communal coping of 467 African American married and cohabiting couples. Data from the sampled couples were analyzed using a common fate model, and analyses revealed higher scores on the measure of sanctification were associated with more communal coping; more communal coping was associated with fewer depressive symptoms among women and men, and …

Perceived Stress And Suicidal Ideation: The Role Of Dispositional Mindfulness, Emma H. Moscardini, Anthony Robinson, Jessica Gerner, Raymond P. Tucker

Faculty Publications

Objectives: Extant literature suggests that dispositional mindfulness may reduce the impact perceived stress has on the severity of suicidal ideation (SI). Only one study has analyzed this question but did so with a cross-sectional design in a sample of undergraduate women. Methods: This study analyzed the potential moderating role of dispositional mindfulness on the relation between perceived stress and SI cross-sectionally and at one-week follow-up in a sample of US adults (N = 598) with a history of SI. Results: Results indicated that dispositional mindfulness and its facets were inversely related to perceived stress, SI severity at baseline, and SI …

Nod Mice Have Distinct Metabolic And Immunologic Profiles When Compared With Genetically Similar Mhc-Matched Icr Mice, Heidi M. Batdorf, Luz De Luna Lawes, Jeremy T. Richardson, David H. Burk, Samuel D. Dupuy, Michael D. Karlstad, Robert C. Noland, Susan J. Burke, J. Jason Collier

Division of Basic Science Faculty Publications

Nonobese diabetic (NOD) mice are the most commonly used rodent model to study mechanisms relevant to the autoimmunity and immunology of type 1 diabetes. Although many different strains of mice have been used as controls for studies comparing nondiabetic lines to the NOD strain, we hypothesized that the parental strain that gave rise to the NOD line might be one of the best options. Therefore, we compared female ICR and NOD mice, which are matched at key major histocompatibility complex (MHC) loci, to understand their metabolic and immunologic similarities and differences. Several novel observations emerged: 1) NOD mice have greater …

Genetic Deletion Of Dnajb3 Using Crispr-Cas9, Produced Discordant Phenotypes, Shadi Nejat, Kalhara R. Menikdiwela, Aliyah Efotte, Shane Scoggin, Bolormaa Vandanmagsar, Paul J. Thornalley, Mohammed Dehbi, Naima Moustaid-Moussa

Division of Basic Science Faculty Publications

Several pathways and/or genes have been shown to be dysregulated in obesity-induced insulin resistance (IR) and type 2 diabetes (T2D). We previously showed, for the first time, impaired expression of DNAJB3 mRNA and protein in subjects with obesity, which was concomitant with increased metabolic stress. Restoring the normal expression of DNAJB3 attenuated metabolic stress and improved insulin signaling both in vivo and in vitro, suggesting a protective role of DNAJB3 against obesity and T2D. The precise underlying mechanisms remained, however, unclear. This study was designed to confirm the human studies in a mouse model of dietary obesity-induced insulin resistance, and, …

Soluble Rage And Skeletal Muscle Tissue Rage Expression Profiles In Lean And Obese Young Adults Across Differential Aerobic Exercise Intensities, Edwin R. Miranda, Jacob T. Mey, Brian K. Blackburn, Alec B. Chaves, Kelly N.Z. Fuller, Ryan K. Perkins, Andrew T. Ludlow, Jacob M. Haus

Division of Basic Science Faculty Publications

Nearly 40% of Americans have obesity and are at increased risk for developing type 2 diabetes. Skeletal muscle is responsible for >80% of insulin-stimulated glucose uptake that is attenuated by the inflammatory milieu of obesity and augmented by aerobic exercise. The receptor for advanced glycation endproducts (RAGE) is an inflammatory receptor directly linking metabolic dysfunction with inflammation. Circulating soluble isoforms of RAGE (sRAGE) formed either by proteolytic cleavage (cRAGE) or alternative splicing (esRAGE) act as decoys for RAGE ligands, thereby counteracting RAGE-mediated inflammation. We aimed to determine if RAGE expression or alternative splicing of RAGE is altered by obesity in …