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Development Of Accurate Embedded Fracture Models For Naturally Fractured Reservoirs, Harun Ur Rashid Mar 2024

Development Of Accurate Embedded Fracture Models For Naturally Fractured Reservoirs, Harun Ur Rashid

LSU Doctoral Dissertations

Natural fractures play a critical role in the performance of unconventional oil, gas, and geothermal reservoirs due to their prevalent occurrence within these systems. However, modeling these fractures accurately and efficiently is still challenging. This work centers on an extensive analysis of naturally fractured systems and proposes new fracture modeling algorithms that can predict the performance of fractured tight rocks accurately and efficiently. Several researchers have explored various methodologies to accurately and efficiently model fractured reservoirs. Among the approaches that can account for each individual fracture in these reservoirs, the embedded discrete fracture model (EDFM) is one of the most …


Coherent States Of The Laguerre–Gauss Modes, M. P. Morales Rodríguez, O. S. Magaña-Loaiza, B. Perez-Garcia, L. M. Nieto Calzada, F. Marroquín Gutiérrrez, B. M. Rodríguez-Lara Mar 2024

Coherent States Of The Laguerre–Gauss Modes, M. P. Morales Rodríguez, O. S. Magaña-Loaiza, B. Perez-Garcia, L. M. Nieto Calzada, F. Marroquín Gutiérrrez, B. M. Rodríguez-Lara

Faculty Publications

Large quantum photonic systems hold promise for surpassing classical computational limits, yet their state preparation remains a challenge. We propose an alternative approach to study multiparticle dynamics by mapping the excitation mode of these systems to physical properties of the Laguerre–Gauss modes. We construct coherent states establishing a direct link between excitation number dynamics and the evolution of the Laguerre–Gauss modes. This highlights the photon transverse spatial degree of freedom as a versatile platform for testing the fundamental aspects of quantum multiparticle systems.


Investigating Gulf Coast Aquifer System: Stratigraphy Reconstruction, Inverse Modeling, And Groundwater Stress Assessment, Shuo Yang Mar 2024

Investigating Gulf Coast Aquifer System: Stratigraphy Reconstruction, Inverse Modeling, And Groundwater Stress Assessment, Shuo Yang

LSU Doctoral Dissertations

The Mississippi Embayment aquifer system (MEAS) and the Coastal Lowlands aquifer system (CLAS) provide substantial groundwater resources for human activities in the U.S. Gulf Coastal Plain. However, the overexploitation has led to groundwater depletion in the MEAS and the CLAS, threatening sustainable groundwater use. Such concern highlights the crucial need for an advanced understanding of stratigraphy and groundwater in these aquifer systems, which is essential for effective regional groundwater management. This dissertation presents a comprehensive investigation of MEAS and CLAS in the Louisiana and southwestern Mississippi region, encompassing three fundamental dimensions: stratigraphy reconstruction, groundwater modeling, and groundwater stress assessments. A …


Reconsidering The Reliability Of Chemical Process Simulators I: Implementation Of The Murphree And Vaporization Efficiencies, Zachary Braswell, Brian F. Hanley, Holt Ragsdale Mar 2024

Reconsidering The Reliability Of Chemical Process Simulators I: Implementation Of The Murphree And Vaporization Efficiencies, Zachary Braswell, Brian F. Hanley, Holt Ragsdale

Faculty Publications

Most chemical process simulators in widespread use today allow users to apply some type of efficiency correction to individual equilibrium stages or to equilibrium stage sections in order to align the stage or section separation performance more closely to actual tray performance in the field. Some simulators even allow for the use of component efficiencies on individual stages or in stage sections. It is our contention, however, that two of the more commonly available efficiency models, the vaporization efficiency and Murphree vapor phase efficiency, have generally been implemented incorrectly. The three major conceptual inconsistencies are (1) the assumption that the …


"In The Footsteps Of Hercules": The Influence Of Classical Antiquity On Eighteenth-Century Militaries, Scott Madere Mar 2024

"In The Footsteps Of Hercules": The Influence Of Classical Antiquity On Eighteenth-Century Militaries, Scott Madere

LSU Doctoral Dissertations

This project examines the pervasive influence of ancient Roman and Greek figures, historical events, literature, and military methods on the leaders and practitioners of eighteenth-century warfare. Rulers, generals, military theorists, and officers frequently consulted classical histories and literature for solutions to the common military problems of the period – tactical, operational, and strategic – showing remarkable faith in ancient military methods despite their growing dependence on gunpowder weaponry and related technologies. This dissertation examines why this was the case and concludes that classical antiquity not only maintained the credibility of its wisdom in the context of modern warfare, but also …


Modulation Of Methoxyfenozide Release From Lignin Nanoparticles Made Of Lignin Grafted With Pcl By Rop And Acylation Grafting Methods, Alvaro Garcia, Carlos E. Astete, Rafael Cueto, Cristina M. Sabliov Mar 2024

Modulation Of Methoxyfenozide Release From Lignin Nanoparticles Made Of Lignin Grafted With Pcl By Rop And Acylation Grafting Methods, Alvaro Garcia, Carlos E. Astete, Rafael Cueto, Cristina M. Sabliov

Faculty Publications

An efficient and sustainable agriculture calls for the development of novel agrochemical delivery systems able to release agrochemicals in a controlled manner. This study investigated the controlled release of the insecticide methoxyfenozide (MFZ) from lignin (LN) nanoparticles (LNPs). LN-grafted poly(ϵ-caprolactone) (LN-g-PCL) polymers were synthesized using two grafting methods, ring-opening polymerization (ROP)(LN-g-PCLp) and acylation reaction (LN-g-PCLa), creating polymers capable of self-assembling into nanoparticles of different properties, without surfactants. The LN-g-PCLp polymers exhibited a degree of polymerization (DP) from 22 to 101, demonstrating enhanced thermal stability after LN incorporation. LNPs loaded with MFZ exhibited a spherical core-shell structure with a hydrophilic LN …


Pal-Bert: An Improved Question Answering Model, Wenfeng Zheng, Siyu Lu, Zhuohang Cai, Ruiyang Wang, Lei Wang, Lirong Yin Mar 2024

Pal-Bert: An Improved Question Answering Model, Wenfeng Zheng, Siyu Lu, Zhuohang Cai, Ruiyang Wang, Lei Wang, Lirong Yin

Faculty Publications

In the field of natural language processing (NLP), there have been various pre-training language models in recent years, with question answering systems gaining significant attention. However, as algorithms, data, and computing power advance, the issue of increasingly larger models and a growing number of parameters has surfaced. Consequently, model training has become more costly and less efficient. To enhance the efficiency and accuracy of the training process while reducing the model volume, this paper proposes a first-order pruning model PAL-BERT based on the ALBERT model according to the characteristics of question-answering (QA) system and language model. Firstly, a first-order network …


Computational Design Of An Electro-Organocatalyst For Conversion Of Co2 Into Formaldehyde, Foroogh Khezeli, Craig Plaisance Mar 2024

Computational Design Of An Electro-Organocatalyst For Conversion Of Co2 Into Formaldehyde, Foroogh Khezeli, Craig Plaisance

Faculty Publications

Density functional theory calculations employing a hybrid implicit/explicit solvation method were used to explore a new strategy for electrochemical conversion of CO2 using an electro-organocatalyst. A particular structural motif is identified that consists of an electron-rich vicinal enediamine (>N-C═C-N<) backbone, which is capable of activating CO2 by the formation of a C-C bond while subsequently facilitating the transfer of electrons from a chemically inert cathode to ultimately produce formaldehyde. Unlike transition metal-based electrocatalysts, the electro-organocatalyst is not constrained by scaling relations between the formation energies of activated CO2 and adsorbed CO, nor is it expected to be active for the competing hydrogen evolution reaction. The rate-limiting steps are found to occur during two proton-coupled electron transfer (PCET) sequences and are associated with the transfer of a proton from a proton transfer mediator to a carbon atom on the electro-organocatalyst. The difficulty of this step in the second PCET sequence necessitates an electrode potential of −0.85 V vs RHE to achieve the maximum turnover frequency. In addition, it is postulated that the electro-organocatalyst should also be capable of forming long-chain aldehydes by successively carrying out reductive aldol condensation to grow the alkyl chain one carbon at a time.


Deconstructing The Mangrove Carbon Cycle: Gains, Transformation, And Losses, M. F. Adame, N. Cormier, P. Taillardat, N. Iram, A. Rovai, T. M. Sloey, E. S. Yando, J. F. Blanco-Libreros, M. Arnaud, T. Jennerjahn, C. E. Lovelock, D. Friess, G. M.S. Reithmaier, C. A. Buelow, S. M. Muhammad-Nor, R. R. Twilley, R. A. Ribeiro Mar 2024

Deconstructing The Mangrove Carbon Cycle: Gains, Transformation, And Losses, M. F. Adame, N. Cormier, P. Taillardat, N. Iram, A. Rovai, T. M. Sloey, E. S. Yando, J. F. Blanco-Libreros, M. Arnaud, T. Jennerjahn, C. E. Lovelock, D. Friess, G. M.S. Reithmaier, C. A. Buelow, S. M. Muhammad-Nor, R. R. Twilley, R. A. Ribeiro

Faculty Publications

Mangroves are one of the most carbon-dense forests on the Earth and have been highlighted as key ecosystems for climate change mitigation and adaptation. Hundreds of studies have investigated how mangroves fix, transform, store, and export carbon. Here, we review and synthesize the previously known and emerging carbon pathways in mangroves, including gains (woody biomass accumulation, deadwood accumulation, soil carbon sequestration, root and litterfall production), transformations (food web transfer through herbivory, decomposition), and losses (respiration as CO2 and CH4, litterfall export, particulate and dissolved carbon export). We then review the technologies available to measure carbon fluxes in mangroves, their potential, …


Spatial Distribution And Movement Of Atlantic Tarpon (Megalops Atlanticus) In The Northern Gulf Of Mexico, Shane A. Stephens, Michael A. Dance, Michelle Zapp Sluis, Richard J. Kline, Matthew K. Streich, Gregory W. Stunz, Aaron J. Adams, R. J.David Wells, Jay R. Rooker Mar 2024

Spatial Distribution And Movement Of Atlantic Tarpon (Megalops Atlanticus) In The Northern Gulf Of Mexico, Shane A. Stephens, Michael A. Dance, Michelle Zapp Sluis, Richard J. Kline, Matthew K. Streich, Gregory W. Stunz, Aaron J. Adams, R. J.David Wells, Jay R. Rooker

Faculty Publications

Atlantic tarpon (Megalops atlanticus) are capable of long-distance migrations (hundreds of kilometers) but also exhibit resident behaviors in estuarine and coastal habitats. The aim of this study was to characterize the spatial distribution of juvenile tarpon and identify migration pathways of adult tarpon in the northern Gulf of Mexico. Spatial distribution of juvenile tarpon was investigated using gillnet data collected by Texas Parks and Wildlife Department (TPWD) over the past four decades. Generalized additive models (GAMs) indicated that salinity and water temperature played a significant role in tarpon presence, with tarpon occurrences peaking in the fall and increasing over the …


Regulation Of Normal And Aberrant Heterochromatic Gene Silencing In Yeast, Anabelle Acosta Mar 2024

Regulation Of Normal And Aberrant Heterochromatic Gene Silencing In Yeast, Anabelle Acosta

Honors Capstones

No abstract provided.


Influence Of Hesperidin On The Physico-Chemical, Microbiological And Sensory Characteristics Of Frozen Yogurt †, Roberto Cedillos, Ricardo S. Aleman, Ryan Page, Douglas W. Olson, Charles Boeneke, Witoon Prinyawiwatkul, Kayanush Aryana Mar 2024

Influence Of Hesperidin On The Physico-Chemical, Microbiological And Sensory Characteristics Of Frozen Yogurt †, Roberto Cedillos, Ricardo S. Aleman, Ryan Page, Douglas W. Olson, Charles Boeneke, Witoon Prinyawiwatkul, Kayanush Aryana

Faculty Publications

Frozen yogurts contain yogurt culture bacteria, which might impart health benefits to their consumers. Global frozen yogurt market sales are expected to grow by 4.8% by 2028, which represents an important opportunity for the industry, consumers and researchers. Polyphenols are metabolites found in plants which have antioxidant and anti-inflammatory properties and might prevent chronic diseases such as cancer, diabetes and cardiovascular diseases. The objective of this study was to elucidate the effect of the polyphenol hesperidin on the physico-chemical, microbiological and sensory characteristics of frozen yogurts. Hesperidin was incorporated into frozen yogurt at three concentrations (125, 250 and 500 mg/90 …


Identification Of A Chondrocyte-Specific Enhancer In The Hoxc8 Gene, Stephania A. Cormier, Claudia Kappen Mar 2024

Identification Of A Chondrocyte-Specific Enhancer In The Hoxc8 Gene, Stephania A. Cormier, Claudia Kappen

Division of Basic Science Faculty Publications

Hox genes encode transcription factors whose roles in patterning animal body plans during embryonic development are well-documented. Multiple studies demonstrate that Hox genes continue to act in adult cells, in normal differentiation, in regenerative processes, and, with abnormal expression, in diverse types of cancers. However, surprisingly little is known about the regulatory mechanisms that govern Hox gene expression in specific cell types, as they differentiate during late embryonic development, and in the adult organism. The murine Hoxc8 gene determines the identity of multiple skeletal elements in the lower thoracic and lumbar region and continues to play a role in the …


Harmonized Multisite Mri-Based Quantification Of Human Liver Fat And Stiffness: A Pilot Study, Owen T. Carmichael, Maninder Singh, Adil Bashir, Anne M. Russell, Mark Bolding, David T. Redden, Judd Storrs, William R. Willoughby, Candace Howard-Claudio, Daniel S. Hsia, Robert P. Kimberly, Meagan E. Gray, Eric Ravussin, Thomas S. Denney Mar 2024

Harmonized Multisite Mri-Based Quantification Of Human Liver Fat And Stiffness: A Pilot Study, Owen T. Carmichael, Maninder Singh, Adil Bashir, Anne M. Russell, Mark Bolding, David T. Redden, Judd Storrs, William R. Willoughby, Candace Howard-Claudio, Daniel S. Hsia, Robert P. Kimberly, Meagan E. Gray, Eric Ravussin, Thomas S. Denney

Clinical Research Faculty Publications

Background: Nonalcoholic fatty liver disease (NAFLD) is a leading cause of end-stage liver disease. NAFLD diagnosis and follow-up relies on a combination of clinical data, liver imaging, and/or liver biopsy. However, intersite imaging differences impede diagnostic consistency and reduce the repeatability of the multisite clinical trials necessary to develop effective treatments. Purpose/Hypothesis: The goal of this pilot study was to harmonize commercially available 3 T magnetic resonance imaging (MRI) measurements of liver fat and stiffness in human participants across academic sites and MRI vendors. Study Type: Cohort. Subjects: Four community-dwelling adults with obesity. Field strength/Sequence: 1.5 and 3 T, multiecho …


Coastal Wetland Restoration Through The Lens Of Odum's Theory Of Ecosystem Development, Friedrich W. Keppeler, Annette S. Engel, Linda M. Hooper-Bùi, Paola C. López-Duarte, Charles W. Martin, Jill A. Olin, Katelyn J. Lamb, Michael J. Polito, Nancy N. Rabalais, Brian J. Roberts, Erick M. Swenson, Olaf P. Jensen Mar 2024

Coastal Wetland Restoration Through The Lens Of Odum's Theory Of Ecosystem Development, Friedrich W. Keppeler, Annette S. Engel, Linda M. Hooper-Bùi, Paola C. López-Duarte, Charles W. Martin, Jill A. Olin, Katelyn J. Lamb, Michael J. Polito, Nancy N. Rabalais, Brian J. Roberts, Erick M. Swenson, Olaf P. Jensen

Faculty Publications

Advancing ecological restoration assessments requires a more detailed consideration of species interactions and ecosystem processes. Most restoration projects rely on a few metrics not always directly linked with ecological theory. Here, we used Odum's theory of ecosystem development to assess and compare the ecosystem structure and services of created marshes (4–6 years old) with preexisting, reference marshes in a brackish water region of the Mississippi River Delta. We built ecosystem models for created and reference marshes that integrated large datasets of stomach contents, stable isotopes, and taxa abundances. Despite strong resemblance in community structure, created marshes were at an earlier …


Searches For Baryon Number Violation In Neutrino Experiments: A White Paper, P. S.B. Dev, L. W. Koerner, S. Saad, S. Antusch, M. Askins, K. S. Babu, J. L. Barrow, J. Chakrabortty, A. De Gouvêa, Z. Djurcic, S. Girmohanta, I. Gogoladze, M. C. Goodman, A. Higuera, D. Kalra, G. Karagiorgi, E. Kearns, V. A. Kudryavtsev, T. Kutter, M. Malinský, D. A. Martinez Caicedo, R. N. Mohapatra, P. Nath, S. Nussinov, J. P. Ochoa-Ricoux, V. Pec, A. Rafique, J. Rodriguez Rondon, R. Shrock, H. W. Sobel, T. Stokes, M. Strait, R. Svoboda Mar 2024

Searches For Baryon Number Violation In Neutrino Experiments: A White Paper, P. S.B. Dev, L. W. Koerner, S. Saad, S. Antusch, M. Askins, K. S. Babu, J. L. Barrow, J. Chakrabortty, A. De Gouvêa, Z. Djurcic, S. Girmohanta, I. Gogoladze, M. C. Goodman, A. Higuera, D. Kalra, G. Karagiorgi, E. Kearns, V. A. Kudryavtsev, T. Kutter, M. Malinský, D. A. Martinez Caicedo, R. N. Mohapatra, P. Nath, S. Nussinov, J. P. Ochoa-Ricoux, V. Pec, A. Rafique, J. Rodriguez Rondon, R. Shrock, H. W. Sobel, T. Stokes, M. Strait, R. Svoboda

Faculty Publications

Baryon number conservation is not guaranteed by any fundamental symmetry within the standard model, and therefore has been a subject of experimental and theoretical scrutiny for decades. So far, no evidence for baryon number violation has been observed. Large underground detectors have long been used for both neutrino detection and searches for baryon number violating processes. The next generation of large neutrino detectors will seek to improve upon the limits set by past and current experiments and will cover a range of lifetimes predicted by several Grand Unified Theories. In this White Paper, we summarize theoretical motivations and experimental aspects …


Systematic Kmtnet Planetary Anomaly Search. X. Complete Sample Of 2017 Prime-Field Planets, Yoon Hyun Ryu, Andrzej Udalski, Jennifer C. Yee, Weicheng Zang, Yossi Shvartzvald, Cheongho Han, Andrew Gould, Michael D. Albrow, Sun Ju Chung, Kyu Ha Hwang, Youn Kil Jung, In Gu Shin, Hongjing Yang, Sang Mok Cha, Dong Jin Kim, Seung Lee Kim, Chung Uk Lee, Dong Joo Lee, Yongseok Lee, Byeong Gon Park, Richard W. Pogge, Hanyue Wang, Przemek Mróz, Michał K. Szymański, Jan Skowron, Radek Poleski, Igor Soszyński, Paweł Pietrukowicz, Szymon Kozłowski, Krzysztof Ulaczyk, Krzysztof A. Rybicki, Patryk Iwanek, Marcin Wrona Mar 2024

Systematic Kmtnet Planetary Anomaly Search. X. Complete Sample Of 2017 Prime-Field Planets, Yoon Hyun Ryu, Andrzej Udalski, Jennifer C. Yee, Weicheng Zang, Yossi Shvartzvald, Cheongho Han, Andrew Gould, Michael D. Albrow, Sun Ju Chung, Kyu Ha Hwang, Youn Kil Jung, In Gu Shin, Hongjing Yang, Sang Mok Cha, Dong Jin Kim, Seung Lee Kim, Chung Uk Lee, Dong Joo Lee, Yongseok Lee, Byeong Gon Park, Richard W. Pogge, Hanyue Wang, Przemek Mróz, Michał K. Szymański, Jan Skowron, Radek Poleski, Igor Soszyński, Paweł Pietrukowicz, Szymon Kozłowski, Krzysztof Ulaczyk, Krzysztof A. Rybicki, Patryk Iwanek, Marcin Wrona

Faculty Publications

We complete the analysis of planetary candidates found by the KMT AnomalyFinder for the 2017 prime fields that cover ∼13 deg2. We report three unambiguous planets: OGLE-2017-BLG-0640, OGLE-2017-BLG-1275, and OGLE-2017-BLG-1237. The first two of these were not previously identified, while the last was not previously published due to technical complications induced by a nearby variable. We further report that a fourth anomalous event, the previously recognized OGLE-2017-BLG-1777, is very likely to be planetary, although its light curve requires unusually complex modeling because the lens and source both have orbiting companions. One of the three unambiguous planets, OGLE-2017-BLG-1275, is …


A Pragmatic Trial Of A Family-Centered Approach To Childhood Obesity Treatment: Rationale And Study Design, Amanda E. Staiano, Alyssa M. Button, Alison Baker, Robbie Beyl, Anne Marie Conn, Angela Lima, Jeanne Lindros, Robert L. Newton, Richard I. Stein, R. Robinson Welch, Stephen Cook, Denise E. Wilfley Mar 2024

A Pragmatic Trial Of A Family-Centered Approach To Childhood Obesity Treatment: Rationale And Study Design, Amanda E. Staiano, Alyssa M. Button, Alison Baker, Robbie Beyl, Anne Marie Conn, Angela Lima, Jeanne Lindros, Robert L. Newton, Richard I. Stein, R. Robinson Welch, Stephen Cook, Denise E. Wilfley

Population and Public Health Science Faculty Publications

Background: Family-based behavioral treatment (FBT) is an effective intensive health behavior and lifestyle treatment for obesity reduction in children and adolescents, but families have limited access. The purpose of this randomized, pragmatic, comparative effectiveness trial was to examine changes in child relative weight in a 12-month, enhanced standard of care (eSOC) intervention combined with FBT (eSOC+FBT) vs. eSOC alone. Methods: Children aged 6 to 15 years with obesity, and their primary caregiver, were recruited from primary care clinics. Families were randomized 1:1 to eSOC, a staged approach led by the primary care provider that gradually intensified dependent on a child's …


Assembly And Repair Of Photosystem Ii In Chlamydomonas Reinhardtii, Himanshu S. Mehra, Xiaozhuo Wang, Brandon P. Russell, Nidhi Kulkarni, Nicholas Ferrari, Brent Larson, David J. Vinyard Mar 2024

Assembly And Repair Of Photosystem Ii In Chlamydomonas Reinhardtii, Himanshu S. Mehra, Xiaozhuo Wang, Brandon P. Russell, Nidhi Kulkarni, Nicholas Ferrari, Brent Larson, David J. Vinyard

Faculty Publications

Oxygenic photosynthetic organisms use Photosystem II (PSII) to oxidize water and reduce plastoquinone. Here, we review the mechanisms by which PSII is assembled and turned over in the model green alga Chlamydomonas reinhardtii. This species has been used to make key discoveries in PSII research due to its metabolic flexibility and amenability to genetic approaches. PSII subunits originate from both nuclear and chloroplastic gene products in Chlamydomonas. Nuclear-encoded PSII subunits are transported into the chloroplast and chloroplast-encoded PSII subunits are translated by a coordinated mechanism. Active PSII dimers are built from discrete reaction center complexes in a process facilitated by …


Unlocking The Potential Of Artificial Intelligence In Fashion Design And E-Commerce Applications: The Case Of Midjourney, Yanbo Zhang, Chuanlan Liu Mar 2024

Unlocking The Potential Of Artificial Intelligence In Fashion Design And E-Commerce Applications: The Case Of Midjourney, Yanbo Zhang, Chuanlan Liu

Faculty Publications

The fashion industry has shown increasing interest in applying artificial intelligence (AI), yet there is a significant gap in exploring the potential of emerging diffusion-modeling-based AI image-generation systems for fashion design and commerce. Therefore, this study aims to assess the effectiveness of Midjourney, one such AI system, in both fashion design and related commerce applications. We employed the action research approach with the Functional, Expressive, and Aesthetic (FEA) Consumer Needs Model as the theoretical framework. Our research comprised three stages: refining an initial idea into well-defined textual design concepts, facilitating concept development, and validating the preceding observations and reflections by …


Planetary Protection Knowledge Gap Closure Enabling Crewed Missions To Mars, James A. Spry, Bette Siegel, Corien Bakermans, David W. Beaty, Mary Sue Bell, James N. Benardini, Rosalba Bonaccorsi, Sarah L. Castro-Wallace, David A. Coil, Athena Coustenis, Peter T. Doran, Lori Fenton, David P. Fidler, Brian Glass, Stephen J. Hoffman, Fathi Karouia, Joel S. Levine, Mark L. Lupisella, Javier Martin-Torres, Rakesh Mogul, Karen Olsson-Francis, Sandra Ortega-Ugalde, Manish R. Patel, David A. Pearce, Margaret S. Race, Aaron B. Regberg, Petra Rettberg, John D. Rummel, Kevin Y. Sato, Andrew C. Schuerger, Elliot Sefton-Nash, Matthew Sharkey, Nitin K. Singh Mar 2024

Planetary Protection Knowledge Gap Closure Enabling Crewed Missions To Mars, James A. Spry, Bette Siegel, Corien Bakermans, David W. Beaty, Mary Sue Bell, James N. Benardini, Rosalba Bonaccorsi, Sarah L. Castro-Wallace, David A. Coil, Athena Coustenis, Peter T. Doran, Lori Fenton, David P. Fidler, Brian Glass, Stephen J. Hoffman, Fathi Karouia, Joel S. Levine, Mark L. Lupisella, Javier Martin-Torres, Rakesh Mogul, Karen Olsson-Francis, Sandra Ortega-Ugalde, Manish R. Patel, David A. Pearce, Margaret S. Race, Aaron B. Regberg, Petra Rettberg, John D. Rummel, Kevin Y. Sato, Andrew C. Schuerger, Elliot Sefton-Nash, Matthew Sharkey, Nitin K. Singh

Faculty Publications

As focus for exploration of Mars transitions from current robotic explorers to development of crewed missions, it remains important to protect the integrity of scientific investigations at Mars, as well as protect the Earth's biosphere from any potential harmful effects from returned martian material. This is the discipline of planetary protection, and the Committee on Space Research (COSPAR) maintains the consensus international policy and guidelines on how this is implemented. Based on National Aeronautics and Space Administration (NASA) and European Space Agency (ESA) studies that began in 2001, COSPAR adopted principles and guidelines for human missions to Mars in 2008. …


Synergnet: A Graph Neural Network Model To Predict Anticancer Drug Synergy, Mengmeng Liu, Gopal Srivastava, J. Ramanujam, Michal Brylinski Mar 2024

Synergnet: A Graph Neural Network Model To Predict Anticancer Drug Synergy, Mengmeng Liu, Gopal Srivastava, J. Ramanujam, Michal Brylinski

Faculty Publications

Drug combination therapy shows promise in cancer treatment by addressing drug resistance, reducing toxicity, and enhancing therapeutic efficacy. However, the intricate and dynamic nature of biological systems makes identifying potential synergistic drugs a costly and time-consuming endeavor. To facilitate the development of combination therapy, techniques employing artificial intelligence have emerged as a transformative solution, providing a sophisticated avenue for advancing existing therapeutic approaches. In this study, we developed SynerGNet, a graph neural network model designed to accurately predict the synergistic effect of drug pairs against cancer cell lines. SynerGNet utilizes cancer-specific featured graphs created by integrating heterogeneous biological features into …


Broadband Switchable Infrared Absorbers Using Phase-Change Materials, M. Tanvir Emrose, Emily L. Payne, Chenglong You, Georgios Veronis Mar 2024

Broadband Switchable Infrared Absorbers Using Phase-Change Materials, M. Tanvir Emrose, Emily L. Payne, Chenglong You, Georgios Veronis

Faculty Publications

We introduce multilayer structures with the phase-change material Ge2Sb2Te5 (GST) for use as broadband switchable absorbers in the infrared wavelength range. We optimize both the material composition and the layer thicknesses of the multilayer structures, in order to maximize the difference between the absorption for GST in its crystalline phase and the absorption for GST in its amorphous phase in the wavelength range of interest. We show that in the optimized structures near perfect absorption can be switched to very low absorption in a broad wavelength range by switching GST from its crystalline to its amorphous phase. Our optimized lithography-free …


Optimal Querying For Communication-Efficient Admm Using Gaussian Process Regression, Aldo Duarte, Truong X. Nghiem, Shuangqing Wei Mar 2024

Optimal Querying For Communication-Efficient Admm Using Gaussian Process Regression, Aldo Duarte, Truong X. Nghiem, Shuangqing Wei

Faculty Publications

In distributed optimization schemes consisting of a group of agents connected to a central coordinator, the optimization algorithm often involves the agents solving private local sub-problems and exchanging data frequently with the coordinator to solve the global distributed problem. In those cases, the query-response mechanism usually causes excessive communication costs to the system, necessitating communication reduction in scenarios where communication is costly. Integrating Gaussian processes (GP) as a learning component to the Alternating Direction Method of Multipliers (ADMM) has proven effective in learning each agent's local proximal operator to reduce the required communication exchange. A key element for integrating GP …


A Simplified Model For The Study Of Film-Boiling Droplet Motion On Microscale Ratchets, Sheldon Wang, Jeong Tae Ok, Sunggook Park, Mahmoud Elsharafi, Yu Guo Mar 2024

A Simplified Model For The Study Of Film-Boiling Droplet Motion On Microscale Ratchets, Sheldon Wang, Jeong Tae Ok, Sunggook Park, Mahmoud Elsharafi, Yu Guo

Faculty Publications

In this work, we explore a simplified model based on both analytical and computational methods for the study of film-boiling droplet motion on microscale ratchets. We consider a specific ratchet design with the length periods and depth of ratchets much smaller than the size of the droplet. We conclude based on our modeling that for the ratchet configuration considered in this paper, the conduction within the vapor film is the dominant means of heat transfer in comparison with convection and radiation. Furthermore, we demonstrate a more manageable two-dimensional model in which analytical approaches coupled with computational approaches yield reasonably accurate …


Influence Of Petroleum-Based And Bio-Derived Recycling Agents On High-Rap Asphalt Mixtures Performance, Ibrahim Elnaml, Louay N. Mohammad, Gaylon L. Baumgardner, Jun Liu, Samuel Cooper, Samuel Cooper Mar 2024

Influence Of Petroleum-Based And Bio-Derived Recycling Agents On High-Rap Asphalt Mixtures Performance, Ibrahim Elnaml, Louay N. Mohammad, Gaylon L. Baumgardner, Jun Liu, Samuel Cooper, Samuel Cooper

Faculty Publications

Reclaimed asphalt pavement (RAP) has been utilized as a potential partial substitute for virgin asphalt binder in asphalt mixtures. However, a primary concern with increasing RAP content in asphalt mixtures is the cracking potential, attributed to the aged RAP asphalt binder (RAP-binder). To address this, the use of petroleum-based and bio-derived recycling agents (RAs) in enhancing the cracking resistance of high-RAP asphalt mixtures has been explored. The objective of this study is to ascertain the effectiveness of six RAs in mitigating cracking in high-RAP asphalt mixtures. The RAs considered include petroleum-crude-oil-derived aromatic oil, soy oil, and four types of tall-oil-derived …


Assessing The Effectiveness Of Regional Storm Surge Reduction Strategies And Tank Level Structural Mitigation Measures For Aboveground Storage Tanks, Santosh Ghimire, Sabarethinam Kameshwar Mar 2024

Assessing The Effectiveness Of Regional Storm Surge Reduction Strategies And Tank Level Structural Mitigation Measures For Aboveground Storage Tanks, Santosh Ghimire, Sabarethinam Kameshwar

Faculty Publications

The effectiveness of regional storm surge reduction strategies and tank-level structural mitigation measures in reducing the failure probability of aboveground storage tanks (ASTs) were studied. Given past failures during flood and hurricane events, several studies have developed fragility models for ASTs. However, the suitability of these fragility models for different hurricane hazard scenarios is unknown. Furthermore, to combat climate change and sea level rise, several regional storm surge reduction strategies are being proposed. However, the effectiveness of these strategies in improving the safety of ASTs is also unknown. So, herein, a framework was proposed that facilitates assessing the suitability of …


New Features Of Laboratory-Generated Epfrs From 1,2-Dichlorobenzene (Dcb) And 2-Monochlorophenol (Mcp), Lavrent Khachatryan, Marwan Y. Rezk, Divine Nde, Farhana Hasan, Slawomir Lomnicki, Dorin Boldor, Robert Cook, Phillip Sprunger, Randall Hall, Stephania Cormier Feb 2024

New Features Of Laboratory-Generated Epfrs From 1,2-Dichlorobenzene (Dcb) And 2-Monochlorophenol (Mcp), Lavrent Khachatryan, Marwan Y. Rezk, Divine Nde, Farhana Hasan, Slawomir Lomnicki, Dorin Boldor, Robert Cook, Phillip Sprunger, Randall Hall, Stephania Cormier

Faculty Publications

The present research is primarily focused on investigating the characteristics of environmentally persistent free radicals (EPFRs) generated from commonly recognized aromatic precursors, namely, 1,2-dichlorobenzene (DCB) and 2-monochlorophenol (MCP), within controlled laboratory conditions at a temperature of 230 °C, termed as DCB230 and MCP230 EPFRs, respectively. An intriguing observation has emerged during the creation of EPFRs from MCP and DCB utilizing a catalyst 5% CuO/SiO2, which was prepared through various methods. A previously proposed mechanism, advanced by Dellinger and colleagues (a conventional model), postulated a positive correlation between the degree of hydroxylation on the catalyst’s surface (higher hydroxylated, HH and less …


A Study On High-Frequency Bending Fatigue, Microhardness, Tensile Strength, And Microstructure Of Parts Made Using Atomic Diffusion Additive Manufacturing (Adam) And Additive Friction Stir Deposition (Afsd), Hamed Ghadimi Feb 2024

A Study On High-Frequency Bending Fatigue, Microhardness, Tensile Strength, And Microstructure Of Parts Made Using Atomic Diffusion Additive Manufacturing (Adam) And Additive Friction Stir Deposition (Afsd), Hamed Ghadimi

LSU Doctoral Dissertations

This dissertation reports the findings of several studies on the mechanical and microstructural properties of parts made using atomic diffusion additive manufacturing (ADAM) and additive friction stir deposition (AFSD). The design of a small-sized bending-fatigue test specimen for an ultrasonic fatigue testing system is reported in Chapter 1. The design was optimized based on the finite element analysis and analytical solution. The stress–life (S–N) curve is obtained for Inconel alloy 718. Chapter 2 presents the findings of ultrasonic bending-fatigue and tensile tests carried out on the ADAM test specimens. The S-N curves were created in the very high-cycle fatigue regime. …


Producing Digital Reflections Of Reality Through Intercultural Filmmaking And Multisensory Engagement, Trai Thomas Feb 2024

Producing Digital Reflections Of Reality Through Intercultural Filmmaking And Multisensory Engagement, Trai Thomas

LSU Doctoral Dissertations

This thesis analyzes the author’s production of three intercultural, multisensory films situated in New Orleans, encompassing elements both narrative and documentary genres. Intercultural cinema exists in a setting where people of different cultural backgrounds live together in power-inflicted spaces of diaspora, colonialism, and cultural apartheid and the development of the story is centered around exoticism, fetishization, and fascination with the other (Marks 2007, 1). Multisensory media primarily engages through visual perception and auditory input, which create cultural knowledge stored as long-term memory files in the brain (Marks 2007).