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Research On 3d Printing Resin Exposure Properties And Its Application On Centrifugal Microfluidic Platform Based On Fluorescence Detection, Zheng Qiao

LSU Doctoral Dissertations

This dissertation encapsulates significant advancements in the field of SLA 3D printing and centrifugal microfluidics. Central to the research is the development of a novel mathematical model for predicting trapped resin thickness in SLA 3D printing, a groundbreaking contribution that addresses a critical aspect of printing intricate structures. This model, the first to establish a mathematical relationship for resin thickness, is rooted in a comprehensive study of the resin curing process. The research leverages the concept of 'critical dosage' for resin curing, leading to a more refined and theoretically grounded approach for calculating curing thickness. Experimentation further validates the model, …

Enhancement Of Applied Rice Breeding Programs: Exploring Factors Impacting Genomic Selection Accuracy And Discovery Of A Novel Gene For Grain Shape, Maria G. Montiel

LSU Doctoral Dissertations

Plant breeding is a crucial tool in addressing global challenges such as climate change, population growth, and the need for more resilient crops. Rice serves as a staple food for a significant portion of the global population and has served as a model crop for genetic and genomic studies. Genomic selection (GS) has become valuable tool in plant breeding, allowing breeders to predict breeding lines’ performance based on their genotypes. The training (TS) set is a central component of genomic selection and the optimization of the training set is crucial for efficient implementation of genomic selection. The first two objectives …

Surfactant-Specific Ai-Driven Molecular Design: Integrating Generative Models, Predictive Modeling, And Reinforcement Learning For Tailored Surfactant Synthesis, Miriam Nnadili, Andrew N. Okafor, Teslim Olayiwola, David Akinpelu, Revati Kumar, Jose A. Romagnoli

Faculty Publications

Molecular design is a critical aspect of various scientific and industrial fields, where the properties of molecules hold significant importance. In this study, a 3-fold methodology design is presented that leverages the power of generative artificial intelligence (AI), predictive modeling, and reinforcement learning to create tailored molecules with desired properties. This model synergistically combines deep learning techniques with Self-Referencing Embedded Strings (SELFIES) molecular representation to build a generative model that generates valid molecules and a graphical neural network model that accurately forecasts molecular properties. The Variational Autoencoder (VAE) coupled with reinforcement learning helps refine molecule generation based on targeted attributes. …

Magnetic Control Of Nonmagnetic Living Organisms, Ahmed Al Harraq, Min Feng, Hashir M. Gauri, Ram Devireddy, Ankur Gupta, Qing Sun, Bhuvnesh Bharti

Faculty Publications

Living organisms inspire the design of microrobots, but their functionality is unmatched. Next-generation microrobots aim to leverage the sensing and communication abilities of organisms through magnetic hybridization, attaching magnetic particles to them for external control. However, the protocols used for magnetic hybridization are morphology specific and are not generalizable. We propose an alternative approach that leverages the principles of negative magnetostatics and magnetophoresis to control nonmagnetic organisms with external magnetic fields. To do this, we disperse model organisms in dispersions of Fe3O4 nanoparticles and expose them to either uniform or gradient magnetic fields. In uniform magnetic fields, living organisms align …

Building The Church Of San Vitale In Ravenna, Italy, Sally S. Morgan

LSU Master's Theses

This thesis uses the evidence concerning the design and building of the Church of San Vitale in Ravenna to reconstruct, as far as it is possible, the sequence of decisions, activities, and methods that led to the construction of the church, made of bricks and mortar, and whose interiors are covered by glorious colored mosaics and marbles. The historiography on the Church of San Vitale begins with the historian Agnellus, who wrote the Liber pontificalis ecclesiae Ravennatis in the 830s to 840s. According to Agnellus and other sources, the Church of San Vitale was founded by Bishop Ecclesius around 525, …

The Effects Of Global Temperature Change On Radon Exposure In Permafrost Areas, Melaan Bender

LSU Master's Theses

Global temperature increase leads to thawing of permafrost that protects local populations from radiation exposure by blocking radon-222 migrating into dwellings. This study aims at assessing the effects of permafrost thawing on the concentrations of radon in indoor air. An approach is developed to predict the evolution of the ²²²Rn concentrations by various processes including radon exhalation from thawed soil. It is found that as frozen soil thaws, more radon can enter dwellings, increasing the concentration of ²²²Rn in indoor air and elevating radiation-induced health risks. This study provides useful insight that will enhance understanding of potential climate …

Enhancement Of Soybean Growth And Disease Resistance Through Seed-Priming Strategy, Francisco Javier Valle

LSU Master's Theses

Disease pressure and other environmental stresses, especially increasing temperature and drought incidence, accompanied with global climatic change have presented hard challenges to Louisiana soybean producers. The objective of this study was to explore the efficacy of seed priming techniques as new alternatives to improve soybean crop protection to reduce the amount of yield losses caused by biotic and abiotic stresses. In this study, five chemicals were used as priming agents at different concentrations (0.1 mM, 1 mM, and 10 mM) to evaluate their effectiveness in enhancing disease tolerance and yield in soybeans. A seed priming procedure was developed by partially …

Investigating The Role Of Fluid Shear Stress During Metastasis On Enhanced Breast Cancer Extravasation, Alejandra M. Ham

LSU Master's Theses

In 2022, ~288,000 American women were diagnosed with metastatic breast cancer which was the leading cause of patient mortality with ~43,000 American women succumbing to the disease. Women can be diagnosed with four different molecular subtypes of breast cancer: luminal A, luminal B, human epithelial growth receptor type 2 enriched (HER2+), and triple-negative breast cancer (TNBC). TNBC accounts for ~12% of all breast cancers, yet it has the worst outcomes. TNBC is highly invasive, with ~46% of TNBC patients developing metastatic disease. A further understanding of metastatic TNBC is needed to provide a greater understanding of how to treat this …

Assessment Of Engineering Performance And Environmental Impacts Of High Reclaimed Asphalt Pavement (Rap) Asphalt Mixtures In Flexible Pavements, Ibrahim A.I.E. Elnaml

LSU Doctoral Dissertations

Due to the critical role of asphalt pavements in national infrastructure development, there is a pressing need to investigate more sustainable materials and approaches. The use of natural aggregates and asphalt binders in asphalt pavement presents sustainability challenges due to the depletion of finite resources. Recycling Asphalt Pavement (RAP) offers a promising sustainable solution by substituting virgin aggregates and asphalt binders with recycled ones. However, increasing RAP contents in asphalt mixtures (>25%) can lead to premature cracking, insufficient durability, and limited longevity due to the presence of aged RAP-asphalt binder. To address these concerns, the application of novel recycling …

Computational Modeling Of Nanoscale Interaction Of Plasmonic Materials With 2d Materials For Sensing Applications, Maria Iftesum

LSU Master's Theses

Plasmonics is a new and exciting field that has the potential to advance many different types of technology, from information processing and energy harvesting to sensing and imaging. The broad field of plasmonic materials and their potential to improve the functionality of cutting-edge technologies are examined in this thesis.

The thesis explores the synthesis, characterization, and manipulation of plasmonic materials after providing an overview of the basic ideas behind plasmonics. Their distinct plasmonic properties and possible uses are clarified by a thorough investigation of a variety of materials, including noble metals, two-dimensional materials, metal oxides and hybrid structures.

A thorough …

Effects Of Treated Effluent Discharge On Tree Water Use And Growth In A Cypress Swamp., Devin Schexnayder

LSU Master's Theses

Inundated baldcypress (Taxodium distichum) trees generally respond to secondarily-treated and disinfected municipal effluent additions with increased growth rates and reduced mortality. Yet, the effects of effluent additions on the water-use and functional traits of inundated mature baldcypress are poorly understood. Because increased tree growth is associated with increased water use, effluent additions may affect the water budget in coastal swamps by increasing water uptake from the rhizosphere due to increased tree transpiration. I used sap flux density (f_d) measurements to assess water-use traits and tree-level daily transpiration (E) in seven mature inundated baldcypress trees that had …

Quantification Of Belowground Biomass And Sediment Accretion In Mangroves Of Different Coastal Environmental Settings Of The Costa Rican Pacific Coast, Denise M. Poveda

LSU Master's Theses

The adaptation of intertidal ecosystems such as mangroves to anticipated accelerated relative sea level rise is dependent on net increase of sediment surface elevations and forest migration inland. Ecosystem models developed to simulate trajectories of ecosystem adaptations have determined that rates of soil formation are most sensitive to surface sediment (organic and inorganic) deposition and subsurface organic production by mangrove roots. Mangrove belowground biomass contributes to soil organic matter accumulation, while mangrove litter has minor contribution due to export and annual decay. In addition to belowground biomass production, inorganic sediment loading is also key contribution to soil formation and accretion. …

“Redención”: Testimonios Of Latinas Who Chose To Leave The Higher Education Industry, Delia P. Madrid-Nothdurft

LSU Doctoral Dissertations

Using the methodological framework of testimonio, this study was an exploration of the experiences of former higher education professionals who identify as women in the Latinx community. Grounded in Latino Critical Theory (LatCrit) and Critical Race Feminism (CRF), this research aims to highlight the narratives of Latina professionals who have separated from the higher education sector. The study is informed by the conceptual framework of Chicana feminist perspective, which contextualizes the analysis of these experiences within a socio-cultural context. Using semi-structured interviews, participants shared their testimonios, providing rich accounts of their journeys and challenges within higher education. Through thematic …

Thermal Frontal Polymerization – Applications In Coatings And Composites, Maria Martinez

LSU Doctoral Dissertations

Thermal frontal polymerization has long been used as a method to cure composites and coatings. However, this is the first time these applications have been used without the use of a catalyst, for the case of composites and coatings.

Chapter 2 discusses how to optimize cure-on-demand, thin layer coatings, using frontal polymerization. Previously, for the use of curing thin layer coating using thermal FP, it was known to just make the formulation viscous enough, as this would prevent premature quenching caused by heat loss. It was discovered that for a given layer thickness, a minimum viscosity and initiator concentration were …

Profiling Of Voltage-Gated Sodium Channel Subtype Expression And Resulting Susceptibility To Targeted Osmotic Lysis In Cancer, Spencer Gerard Lemoine

LSU Doctoral Dissertations

Cancer is a disease characterized by a wide array of dysregulated cellular function, activity, and growth. At times, specific dysregulations associated with cancer can be exploited as avenues of potential treatment. The sodium handling mechanisms and their associated proteins in cancer have received closer attention recently closely as such a potential mechanism to exploit for treating advanced cancer. Some novel treatments aim to inhibit the expression or activity of these sodium handling proteins in an attempt to prevent the cancer from advancing or becoming more aggressive; however, such approaches have had limited success. Targeted osmotic lysis (TOL) is a new …

Introducing Chinese Folk Songs Through Arrangements For Trombone & Piano And Chamber Music, Tianyu Xue

LSU Doctoral Dissertations

The scarcity of trombone in traditional Chinese music reflects the limited exposure and education for the trombone in China. Additionally, Chinese folk songs have minimal presence on the global stage. This project will bridge this gap by developing a series of trombone pieces that incorporate Chinese musical elements, explicitly focusing on elevating Chinese folk songs through trombone performance. This initiative offers an opportunity for trombonists worldwide to delve into the richness of Chinese folk music. The core of this work involves selecting Chinese folk songs that represent diverse historical contexts, regional characteristics, and emotional content and then arranging them for …

Geospatial Analysis Of Historical Tropical Cyclone Intensity And Rainfall In Georgia, United States, Reilly T. Corkran

LSU Master's Theses

Tropical cyclones, characterized by their high wind speeds and heavy rainfall, cause widespread devastation, affecting millions of people and leading to economic losses worldwide. Tropical cyclone-specific research in Georgia is scarce, likely due to the coast’s minimal geographical extent and the relative infrequency of direct landfalls. Research on Georgia tropical cyclones does not account for storms that make landfall in Florida and continue north, northeast, or northwest. In 2018, Hurricane Michael generated $4.7 billion in property, agriculture, and forestry damages across southwest Georgia as a Category 3 hurricane. With an increasing population, property development, and agriculture sector sensitive to tropical …

Improving Implicit Communication In Remote Collaboration Through Augmented Reality And Digital Twins, Nicholas Levergne

LSU Master's Theses

Large scale digital twinning projects are beginning to emerge across the tech industry. Within these projects is a desire to integrate augmented reality capabilities into industrial workflows. However, research on augmented reality technology for remote collaboration lacks ecologically valid studies of real world scenarios. Additionally, prior remote collaboration literature is focused on white-collar applications instead of blue-collar field work. Prior AR collaboration software is similarly limited, with most software allowing mixed camera views and annotation that requires participants to be stationary. This thesis introduces SpectAR, an augmented reality and desktop remote collaboration software suite developed in Unreal Engine 5.1.1. SpectAR …

Automated Reinforcement During Large-Scale Additive Manufacturing: Structural Assessment Of A Dual Approach, Hassan Ahmed, Ilerioluwa Giwa, Daniel Game, Gabriel Arce, Hassan Noorvand, Marwa Hassan, Ali Kazemian

Faculty Publications

Automated and seamless integration of reinforcement is one of the main unresolved challenges in large-scale additive construction. This study leverages a dual-reinforcement solution consisting of high-dosage steel fiber (up to 2.5% by volume) and short vertical reinforcements as a complementary reinforcement technique for 3D-printed elements. The mechanical performance of the printing material was characterized by measuring the compressive, flexural, and uniaxial tensile strengths of mold-cast specimens. Furthermore, the flexural performance of the plain and fiber-reinforced 3D-printed beams was evaluated in the three main loading directions (X, Y, and Z-directions in-plane). In addition, short vertical threaded reinforcements were inserted into the …

Generative Artificial Intelligence And Building Design: Early Photorealistic Render Visualization Of Façades Using Local Identity-Trained Models, Hayoung Jo, Jin Kook Lee, Yong Cheol Lee, Seungyeon Choo

Faculty Publications

This paper elucidates an approach that utilizes generative artificial intelligence (AI) to develop alternative architectural design options based on local identity. The advancement of AI technologies has increasingly piqued the interest of the architecture, engineering, construction, and facility management industry. Notably, the topic of "visualization"has gained prominence as a means for enhancing communication related to a project, especially in the early phases of design. This study aims to enhance the ease of obtaining design images during initial phases of design by drawing from multiple texts and images. It develops an additional training model to generate various design alternatives that resonate …

From Authenticity To Abandonment: A Case Study On The Decline Of Bereal, Blake Bollinger

Honors Capstones

No abstract provided.

Bistro Mélange Business Plan, Cade Acosta

Honors Capstones

No abstract provided.

Louisiana Agriculture Magazine, Spring 2024, Lsu Agcenter

Louisiana Agriculture

Louisiana’s warm, subtropical climate allows producers to raise an array of crops and livestock. It also provides challenges. Tropical storm winds can lay down rice and cane crops. Ample rain can turn into crop-damaging floods. Last year, a drought struck the southeastern United States, leading to more than $100 million in losses for the cattle sector.

In these cases, LSU AgCenter specialists respond to individual producers’ needs. In each parish AgCenter Extension agents help connect producers with needed resources and become a conduit for the latest knowledge gleaned from scientists at AgCenter research stations across the state.

This issue of …

Functional And Multi-Omics Effects Of An Optimized Crispr-Mediated Furin Depletion In U937 Monocytes, Ruiming Chua, Lijin Wang, Roshni Singaraja, Sujoy Ghosh

Division of Basic Science Faculty Publications

The pro-protein convertase FURIN (PCSK3) is implicated in a wide range of normal and pathological biological processes such as infectious diseases, cancer and cardiovascular diseases. Previously, we performed a systemic inhibition of FURIN in a mouse model of atherosclerosis and demonstrated significant plaque reduction and alterations in macrophage function. To understand the cellular mechanisms affected by FURIN inhibition in myeloid cells, we optimized a CRISPR-mediated gene deletion protocol for successfully deriving hemizygous (HZ) and nullizygous (NZ) FURIN knockout clones in U937 monocytic cells using lipotransfection-based procedures and a dual guide RNA delivery strategy. We observed differences in monocyte and macrophage …

Preferential Hydrologic States And Tipping Characteristics Of Global Surface Soil Moisture, Vinit Sehgal, Binayak P. Mohanty

Faculty Publications

A dynamic transition in soil hydrologic states through meteorological variability and terrestrial feedback governs soil-vegetation-climate (SVC) interactions, constrained by critical soil moisture (SM) thresholds. However, observational and scaling constraints limit critical SM threshold estimation at the remote-sensing (RS) footprint scale. Using global surface SM (θRS) from NASA’s Soil Moisture Active Passive (SMAP) satellite, we characterize the seasonal preferential hydrologic states of θRS and derive three tipping characteristics to estimate the intensity (Mean Tipping Depth, (Formula presented.)), frequency (Tipping Count, η), and duration (Mean Tipped Time, (Formula presented.)) of the excursion of θRS from wet- to dry-average conditions. The preferential state …

Embryonic Exposure To Benzotriazole Ultraviolet Stabilizer 327 Alters Behavior Of Rainbow Trout Alevin, Andreas N.M. Eriksson, Justin Dubiel, Lauren Zink, Zhe Lu, Jon A. Doering, Steve Wiseman

Faculty Publications

Benzotriazole ultraviolet (UV) stabilizers (BUVSs) are used in great quantities during industrial production of a variety of consumer and industrial goods. As a result of leaching and spill, BUVSs are detectable ubiquitously in the environment. As of May 2023, citing concerns related to bioaccumulation, biomagnification, and environmental persistence, (B)UV(S)-328 was recommended to be listed under Annex A of the Stockholm Convention on Persistent Organic Pollutants. However, a phaseout of UV-328 could result in a regrettable substitution because the replacement chemical(s) could cause similar or unpredicted toxicity in vivo, relative to UV-328. Therefore, the influence of UV-327, a potential replacement of …

A Joint Fermi-Gbm And Swift-Bat Analysis Of Gravitational-Wave Candidates From The Third Gravitational-Wave Observing Run, C. Fletcher, J. Wood, R. Hamburg, P. Veres, C. M. Hui, E. Bissaldi, M. S. Briggs, E. Burns, W. H. Cleveland, M. M. Giles, A. Goldstein, B. A. Hristov, D. Kocevski, S. Lesage, B. Mailyan, C. Malacaria, S. Poolakkil, A. Von Kienlin, C. A. Wilson-Hodge, M. Crnogorčević, J. Delaunay, A. Tohuvavohu, R. Caputo, S. B. Cenko, S. Laha, T. Parsotan, R. Abbott, H. Abe, F. Acernese, K. Ackley, N. Adhikari, R. X. Adhikari, V. K. Adkins

Faculty Publications

We present Fermi Gamma-ray Burst Monitor (Fermi-GBM) and Swift Burst Alert Telescope (Swift-BAT) searches for gamma-ray/X-ray counterparts to gravitational-wave (GW) candidate events identified during the third observing run of the Advanced LIGO and Advanced Virgo detectors. Using Fermi-GBM onboard triggers and subthreshold gamma-ray burst (GRB) candidates found in the Fermi-GBM ground analyses, the Targeted Search and the Untargeted Search, we investigate whether there are any coincident GRBs associated with the GWs. We also search the Swift-BAT rate data around the GW times to determine whether a GRB counterpart is present. No counterparts are found. Using both the Fermi-GBM Targeted Search …

Biochar-Based Materials As Remediation Strategy In Petroleum Hydrocarbon-Contaminated Soil And Water: Performances, Mechanisms, And Environmental Impact, Zhuo Wei, Yi Wei, Yang Liu, Shuai Niu, Yaxi Xu, Jong Hwan Park, Jim J. Wang

Faculty Publications

Petroleum contamination is considered as a major risk to the health of humans and environment. Biochars as low-cost and eco-friendly carbon materials, have been widely used for the removal of petroleum hydrocarbon in the environment. The purpose of this paper is to review the performance, mechanisms, and potential environmental toxicity of biochar, modified biochar and its integration use with other materials in petroleum contaminated soil and water. Specifically, the use of biochar in oil-contaminated water and soil as well as the factors that could influence the removal ability of biochar were systematically evaluated. In addition, the modification and integrated use …

The Association Between Diet Quality And Glycemic Outcomes Among People With Type 1 Diabetes, Melanie B. Gillingham, Martin Chase Marak, Michael C. Riddell, Peter Calhoun, Robin L. Gal, Susana R. Patton, Peter G. Jacobs, Jessica R. Castle, Mark A. Clements, Francis J. Doyle, Michael R. Rickels, Corby K. Martin

Clinical Research Faculty Publications

Background: The amount and type of food consumed impacts the glycemic response and insulin needs of people with type 1 diabetes mellitus (T1DM). Daily variability in consumption, reflected in diet quality, may acutely impact glycemic levels and insulin needs. Objective: Type 1 Diabetes Exercise Initiative (T1DEXI) data were examined to evaluate the impact of daily diet quality on near-term glycemic control and interaction with exercise. Methods: Using the Remote Food Photography Method, ≤8 d of dietary intake data were analyzed per participant. Diet quality was quantified with the Healthy Eating Index-2015 (HEI), where a score of 100 indicates the highest-quality …

Effects Of Wind On The Stability Of Explosive Eruption Plumes, Tyler Paladino, Shannon Kobs Nawotniak, Bryan Nicholson, Suniti Karunatillake

Faculty Publications

Explosive volcanic eruptions can produce eruption plumes and pyroclastic density currents that can severely damage life and property. While many factors influence eruption plume stability, including mass eruption rate, grain size distribution, and environmental factors, the role of wind is complicated, with evidence for wind as both a stabilizing and destabilizing factor. Here we use the Active Tracer High-resolution Atmospheric Model (ATHAM) to simulate 980 plumes with differing eruptive parameters, atmospheric profiles, and wind conditions to isolate how and when wind can lead to column collapse. We analyze these simulations via a novel method that provides stability percentage via an …