Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Louisiana State University

Discipline
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 6811 - 6840 of 13619

Full-Text Articles in Entire DC Network

Oil Impacts On Coastal Wetlands: Implications For The Mississippi River Delta Ecosystem After The Deepwater Horizon Oil Spill, Irving A. Mendelssohn, Gary L. Andersen, Donald M. Baltz, Rex H. Caffey, Kevin R. Carman, John W. Fleeger, Samantha B. Joye, Qianxin Lin, Edward Maltby, Edward B. Overton, Lawrence P. Rozas Jun 2012

Oil Impacts On Coastal Wetlands: Implications For The Mississippi River Delta Ecosystem After The Deepwater Horizon Oil Spill, Irving A. Mendelssohn, Gary L. Andersen, Donald M. Baltz, Rex H. Caffey, Kevin R. Carman, John W. Fleeger, Samantha B. Joye, Qianxin Lin, Edward Maltby, Edward B. Overton, Lawrence P. Rozas

Faculty Publications

On 20 April 2010, the Deepwater Horizon explosion, which released a US governmentestimated 4.9 million barrels of crude oil into the Gulf of Mexico, was responsible for the death of 11 oil workers and, possibly, for an environmental disaster unparalleled in US history. For 87 consecutive days, the Macondo well continuously released crude oil into the Gulf of Mexico. Many kilometers of shoreline in the northern Gulf of Mexico were affected, including the fragile and ecologically important wetlands of Louisiana's Mississippi River Delta ecosystem. These wetlands are responsible for a third of the nation's fish production and, ironically, help to …

Go to article

Chaos Representations For Marked Point Processes, Samuel N Cohen Jun 2012

Chaos Representations For Marked Point Processes, Samuel N Cohen

Communications on Stochastic Analysis

No abstract provided.

Go to article

Costs And Benefits Of Jasmonic Acid Induced Responses In Soybean, A. K. Accamando, J. T. Cronin Jun 2012

Costs And Benefits Of Jasmonic Acid Induced Responses In Soybean, A. K. Accamando, J. T. Cronin

Faculty Publications

In response to herbivory, plants have evolved defense strategies to reduce herbivore preference and performance. A strategy whereby defenses are induced only upon herbivory can mitigate costs of defense when herbivores are scarce. Although costs and benefits of induced responses are generally assumed, empirical evidence for many species is lacking. Soybean (Glycine max L. Merr.) has emerged as a model species with which to address questions about induced responses. To our knowledge, this is the first study to examine the fitness costs and benefits of jasmonic acid-induced responses by soybean in the absence and presence of soybean loopers (Chrysodeix includens …

Go to article

High-Amylose Resistant Starch Increases Hormones And Improves Structure And Function Of The Gastrointestinal Tract: A Microarray Study, Michael J. Keenan, Roy J. Martin, Anne M. Raggio, Kathleen L. Mccutcheon, Ian L. Brown, Anne Birkett, Susan S. Newman, Jihad Skaf, Maren Hegsted, Richard T. Tulley, Eric Blair, June Zhou Jun 2012

High-Amylose Resistant Starch Increases Hormones And Improves Structure And Function Of The Gastrointestinal Tract: A Microarray Study, Michael J. Keenan, Roy J. Martin, Anne M. Raggio, Kathleen L. Mccutcheon, Ian L. Brown, Anne Birkett, Susan S. Newman, Jihad Skaf, Maren Hegsted, Richard T. Tulley, Eric Blair, June Zhou

Faculty Publications

Background/Aims: Type 2 resistant starch from high-amylose maize (HAM-RS2) is associated with increased fermentation, increased expression of proglucagon (gene for GLP-1) and peptide YY (PYY) genes in the large intestine, and improved health. To determine what other genes are up- or downregulated with feeding of HAM-RS2, a microarray was performed. Methods: Adult, male Sprague Dawley rats were fed one of the following three diets for a 4-week study period: cornstarch control (CC, 3.74 kcal/g), dietary energy density control (EC, 3.27 kcal/g), and 30% HAM-RS2 (RS, 3.27 kcal/g). Rat microarray with ∼27,000 genes and validation of 94 representative genes with multiple …

Go to article

Exploring Post-Translational Arginine Modification Using Chemically Synthesized Methylglyoxal Hydroimidazolones, Tina Wang, Rendy Kartika, David A. Spiegel May 2012

Exploring Post-Translational Arginine Modification Using Chemically Synthesized Methylglyoxal Hydroimidazolones, Tina Wang, Rendy Kartika, David A. Spiegel

Faculty Publications

The methylglyoxal-derived hydroimidazolones (MG-Hs) comprise the most prevalent class of non-enzymatic, post-translational modifications of protein arginine residues found in nature. These adducts form spontaneously in the human body, and are also present at high levels in the human diet. Despite numerous lines of evidence suggesting that MG-H-arginine adducts play critical roles in both healthy and disease physiology in humans, detailed studies of these molecules have been hindered by a lack of general synthetic strategies for their preparation in chemically homogeneous form, and on scales sufficient to enable detailed biochemical and cellular investigations. To address this limitation, we have developed efficient, …

Go to article

Loss Of Mhc And Neutral Variation In Peary Caribou: Genetic Drift Is Not Mitigated By Balancing Selection Or Exacerbated By Mhc Allele Distributions, Sabrina S. Taylor, Deborah A. Jenkins, Peter Arcese May 2012

Loss Of Mhc And Neutral Variation In Peary Caribou: Genetic Drift Is Not Mitigated By Balancing Selection Or Exacerbated By Mhc Allele Distributions, Sabrina S. Taylor, Deborah A. Jenkins, Peter Arcese

Faculty Publications

Theory and empirical results suggest that the rate of loss of variation at Mhc and neutral microsatellite loci may differ because selection influences Mhc genes, and because a high proportion of rare alleles at Mhc loci may result in high rates of loss via drift. Most published studies compare Mhc and microsatellite variation in various contemporary populations to infer the effects of population size on genetic variation, even though different populations are likely to have different demographic histories that may also affect contemporary genetic variation. We directly compared loss of variation at Mhc and microsatellite loci in Peary caribou by …

Go to article

The African Cichlid Fish Astatotilapia Burtoni Uses Acoustic Communication For Reproduction: Sound Production, Hearing, And Behavioral Significance, Karen P. Maruska, Uyhun S. Ung, Russell D. Fernald May 2012

The African Cichlid Fish Astatotilapia Burtoni Uses Acoustic Communication For Reproduction: Sound Production, Hearing, And Behavioral Significance, Karen P. Maruska, Uyhun S. Ung, Russell D. Fernald

Faculty Publications

Sexual reproduction in all animals depends on effective communication between signalers and receivers. Many fish species, especially the African cichlids, are well known for their bright coloration and the importance of visual signaling during courtship and mate choice, but little is known about what role acoustic communication plays during mating and how it contributes to sexual selection in this phenotypically diverse group of vertebrates. Here we examined acoustic communication during reproduction in the social cichlid fish, Astatotilapia burtoni. We characterized the sounds and associated behaviors produced by dominant males during courtship, tested for differences in hearing ability associated with female …

Go to article

Adrenergic Alpha-1 Pathway Is Associated With Hypertension Among Nigerians In A Pathway-Focused Analysis, Nicholas P. Reder, Bamidele O. Tayo, Babatunde Salako, Adesola Ogunniyi, Adebowale Adeyemo, Charles Rotimi, Richard S. Cooper May 2012

Adrenergic Alpha-1 Pathway Is Associated With Hypertension Among Nigerians In A Pathway-Focused Analysis, Nicholas P. Reder, Bamidele O. Tayo, Babatunde Salako, Adesola Ogunniyi, Adebowale Adeyemo, Charles Rotimi, Richard S. Cooper

Faculty Publications

Background: The pathway-focused association approach offers a hypothesis driven alternative to the agnostic genome-wide association study. Here we apply the pathway-focused approach to an association study of hypertension, systolic blood pressure (SBP), and diastolic blood pressure (DBP) in 1614 Nigerians with genome-wide data. Methods and Results: Testing of 28 pathways with biological relevance to hypertension, selected a priori, containing a total of 101 unique genes and 4,349 unique single-nucleotide polymorphisms (SNPs) showed an association for the adrenergic alpha 1 (ADRA1) receptor pathway with hypertension (pp>10-5) SNPs offers a novel method for detecting the "missing heritability" of hypertension. These findings …

Go to article

Optimizing The Air Dissolution Parameters In An Unpacked Dissolved Air Flotation System, Adam Dassey, Chandra Theegala May 2012

Optimizing The Air Dissolution Parameters In An Unpacked Dissolved Air Flotation System, Adam Dassey, Chandra Theegala

Faculty Publications

Due to the various parameters that influence air solubility and microbubble production in dissolved air flotation (DAF), a multitude of values that cover a large range for these parameters are suggested for field systems. An unpacked saturator and an air quantification unit were designed to specify the effects of power, pressure, temperature, hydraulic retention time, and air flow on the DAF performance. It was determined that a pressure of 621 kPa, hydraulic retention time of 18.2 min, and air flow of 8.5 L/h would be the best controlled parameters for maximum efficiency in this unit. A temperature of 7 °C …

Go to article

Multiple Deletions Reveal The Essentiality Of The Deda Membrane Protein Family In Escherichia Coli, Lisa A. Boughner, William T. Doerrler May 2012

Multiple Deletions Reveal The Essentiality Of The Deda Membrane Protein Family In Escherichia Coli, Lisa A. Boughner, William T. Doerrler

Faculty Publications

The DedA family is a highly conserved, ancient family of membrane proteins with representatives in most sequenced genomes. A characteristic of prokaryotic DedA family genes is extensive gene duplication, with most bacterial genomes carrying two or more homologues. The Escherichia coli genome carries eight DedA genes, each individually nonessential. We previously described an E. coli mutant (BC202; ΔyghB:: kanR, ΔyqjA:: tetR) with in-frame deletions of two DedA genes encoding proteins with 61% amino acid identity. BC202 fails to complete cell division or grow at elevated temperatures. Here, we report that restoration of normal growth and cell division of BC202 is …

Go to article

The Future Workforce In Cancer Prevention: Advancing Discovery, Research, And Technology, Wayne D. Newhauser, Michael E. Scheurer, Jessica M. Faupel-Badger, Jessica Clague, Jeffrey Weitzel, Kendra V. Woods May 2012

The Future Workforce In Cancer Prevention: Advancing Discovery, Research, And Technology, Wayne D. Newhauser, Michael E. Scheurer, Jessica M. Faupel-Badger, Jessica Clague, Jeffrey Weitzel, Kendra V. Woods

Faculty Publications

As part of a 2-day conference on October 15 and 16, 2009, a nine-member task force composed of scientists, clinicians, educators, administrators, and students from across the USA was formed to discuss research, discovery, and technology obstacles to progress in cancer prevention and control, specifically those related to the cancer prevention workforce. This article summarizes the task force's findings on the current state of the cancer prevention workforce in this area and its needs for the future. The task force identified two types of barriers impeding the current cancer prevention workforce in research, discovery, and technology from reaching its fullest …

Go to article

Reno: Regularized Non-Parametric Analysis Of Protein Lysate Array Data, Bin Li, Feng Liang, Jianhua Hu, Xuming He May 2012

Reno: Regularized Non-Parametric Analysis Of Protein Lysate Array Data, Bin Li, Feng Liang, Jianhua Hu, Xuming He

Faculty Publications

Motivation: The reverse-phase protein lysate arrays have been used to quantify the relative expression levels of a protein in a number of cellular samples simultaneously. To avoid quantification bias due to mis-specification of commonly used parametric models, a nonparametric approach based on monotone response curves may be used. The existing methods, however, aggregate the protein concentration levels of replicates of each sample, and therefore fail to account for within-sample variability. Results: We propose a method of regularization on protein concentration estimation at the level of individual dilution series to account for within-sample or within-group variability. We use an efficient algorithm …

Go to article

Exploring The Regulation Of Neuronal Nitric Oxide Synthase In Retinal Amacrine Cells, Glynis B. Mattheisen May 2012

Exploring The Regulation Of Neuronal Nitric Oxide Synthase In Retinal Amacrine Cells, Glynis B. Mattheisen

Honors Capstones

No abstract provided.

Go to article

Enhanced Salt Stress Tolerance Of Rice Plants Expressing A Vacuolar H +-Atpase Subunit C1 (Savhac1) Gene From The Halophyte Grass Spartina Alterniflora Löisel, Niranjan Baisakh, Mangu V. Ramanarao, Kanniah Rajasekaran, Prasanta Subudhi, Jaroslav Janda, David Galbraith, Cheryl Vanier, Andy Pereira May 2012

Enhanced Salt Stress Tolerance Of Rice Plants Expressing A Vacuolar H +-Atpase Subunit C1 (Savhac1) Gene From The Halophyte Grass Spartina Alterniflora Löisel, Niranjan Baisakh, Mangu V. Ramanarao, Kanniah Rajasekaran, Prasanta Subudhi, Jaroslav Janda, David Galbraith, Cheryl Vanier, Andy Pereira

Faculty Publications

The physiological role of a vacuolar ATPase subunit c1 (SaVHAc1) from a halophyte grass Spartina alterniflora was studied through its expression in rice. The SaVHAc1-expressing plants showed enhanced tolerance to salt stress than the wild-type plants, mainly through adjustments in early stage and preparatory physiological responses. In addition to the increased accumulation of its own transcript, SaVHAc1 expression led to increased accumulation of messages of other native genes in rice, especially those involved in cation transport and ABA signalling. The SaVHAc1-expressing plants maintained higher relative water content under salt stress through early stage closure of the leaf stoma and reduced …

Go to article

Control Of Aperture Closure Initiation During Trunk-Assisted Reach-To-Grasp Movements, Miya K. Rand, Arend W.A. Van Gemmert, Abul B.M.I. Hossain, Yury P. Shimansky, George E. Stelmach May 2012

Control Of Aperture Closure Initiation During Trunk-Assisted Reach-To-Grasp Movements, Miya K. Rand, Arend W.A. Van Gemmert, Abul B.M.I. Hossain, Yury P. Shimansky, George E. Stelmach

Faculty Publications

The present study investigated how the involvement and direction of trunk movement during reach-to-grasp movements affect the coordination between the transport and grasping components. Seated young adults made prehensile movements in which the involvement of the trunk was varied; the trunk was not involved, moved forward (flexion), or moved backward (extension) in the sagittal plane during the reach to the object. Each of the trunk movements was combined with an extension or flexion motion of the arm during the reach. Regarding the relationship between the trunk and arm motion for arm transport, the onset of wrist motion relative to that …

Go to article

Excavation Of Transect 4 At The Eleanor Betty Site, A Submerged Classic Maya Salt Work, Belize, Taylor Aucoin May 2012

Excavation Of Transect 4 At The Eleanor Betty Site, A Submerged Classic Maya Salt Work, Belize, Taylor Aucoin

Honors Capstones

No abstract provided.

Go to article

Engineering Design Of A Prototype Ammonia Absorption Tower, Andrew Warren Calogero May 2012

Engineering Design Of A Prototype Ammonia Absorption Tower, Andrew Warren Calogero

Honors Capstones

No abstract provided.

Go to article

Phthalocyanine-Peptide Conjugates For Epidermal Growth Factor Receptor Targeting, Benson G. Ongarora, Krystal R. Fontenot, Xiaoke Hu, Inder Sehgal, Seetharama D. Satyanarayana-Jois, Dm Graça H. Vicente Apr 2012

Phthalocyanine-Peptide Conjugates For Epidermal Growth Factor Receptor Targeting, Benson G. Ongarora, Krystal R. Fontenot, Xiaoke Hu, Inder Sehgal, Seetharama D. Satyanarayana-Jois, Dm Graça H. Vicente

Faculty Publications

Four phthalocyanine (Pc)-peptide conjugates designed to target the epidermal growth factor receptor (EGFR) were synthesized and evaluated in vitro using four cell lines: human carcinoma A431 and HEp2, human colorectal HT-29, and kidney Vero (negative control) cells. Two peptide ligands for EGFR were investigated: EGFR-L1 and -L2, bearing 6 and 13 amino acid residues, respectively. The peptides and Pc-conjugates were shown to bind to EGFR using both theoretical (Autodock) and experimental (SPR) investigations. The Pc-EGFR-L1 conjugates 5a and 5b efficiently targeted EGFR and were internalized, in part due to their cationic charge, whereas the uncharged Pc-EGFR-L2 conjugates 4b and 6a …

Go to article

High Dispersal Ability Inhibits Speciation In A Continental Radiation Of Passerine Birds, Santiago Claramunt, Elizabeth P. Derryberry, Jr V. Remsen, Robb T. Brumfield Apr 2012

High Dispersal Ability Inhibits Speciation In A Continental Radiation Of Passerine Birds, Santiago Claramunt, Elizabeth P. Derryberry, Jr V. Remsen, Robb T. Brumfield

Faculty Publications

Dispersal can stimulate speciation byfacilitating geographical expansion across barriers or inhibit speciation by maintaining gene flow among populations. Therefore, the relationship between dispersal ability and speciation rates can be positive or negative. Furthermore, an 'intermediate dispersal' model that combines positive and negative effects predicts a unimodal relationship between dispersal and diversification. Because both dispersal ability and speciation rates are difficult to quantify, empirical evidence for the relationship between dispersal and diversification remains scarce. Using a surrogate for flight performance and a species-level DNA-based phylogeny of a large South American bird radiation (the Furnariidae), we found that lineages with higher dispersal …

Go to article

Ionically Self-Assembled, Multi-Luminophore One-Dimensional Micro- And Nanoscale Aggregates Of Thiacarbocyanine Gumbos, Sergio L. De Rooy, Susmita Das, Min Li, Bilal El-Zahab, Atiya Jordan, Ridgely Lodes, Anna Weber, Lin Chandler, Gary A. Baker, Isiah M. Warner Apr 2012

Ionically Self-Assembled, Multi-Luminophore One-Dimensional Micro- And Nanoscale Aggregates Of Thiacarbocyanine Gumbos, Sergio L. De Rooy, Susmita Das, Min Li, Bilal El-Zahab, Atiya Jordan, Ridgely Lodes, Anna Weber, Lin Chandler, Gary A. Baker, Isiah M. Warner

Faculty Publications

Groups of uniform materials based on organic salts (GUMBOS), derived from thiacarbocyanine (TC)-based dyes with increasing methyne chain lengths, were prepared through a single-step metathesis reaction between the iodide form of the TC dye and lithium bis(perfluoroethylsulfonyl)imide as the lipophilic anion source. Ionic self-assembly of these fluorescent hydrophobic GUMBOS resulted in aqueous dispersions of one-dimensional micro- and nanoscale molecular aggregates. Blended binary and ternary aggregates containing multiple TC GUMBOS were also prepared. These nanostructures exhibited a variety of aspect ratios, affording tunable Förster resonance energy transfer (FRET) and aggregation-dependent spectroscopic properties. © 2012 American Chemical Society.

Go to article

Salinity- And Population-Dependent Genome Regulatory Response During Osmotic Acclimation In The Killifish (Fundulus Heteroclitus) Gill, Andrew Whitehead, Jennifer L. Roach, Shujun Zhang, Fernando Galvez Apr 2012

Salinity- And Population-Dependent Genome Regulatory Response During Osmotic Acclimation In The Killifish (Fundulus Heteroclitus) Gill, Andrew Whitehead, Jennifer L. Roach, Shujun Zhang, Fernando Galvez

Faculty Publications

The killifish Fundulus heteroclitus is abundant in osmotically dynamic estuaries and it can quickly adjust to extremes in environmental salinity. We performed a comparative osmotic challenge experiment to track the transcriptomic and physiological responses to two salinities throughout a time course of acclimation, and to explore the genome regulatory mechanisms that enable extreme osmotic acclimation. One southern and one northern coastal population, known to differ in their tolerance to hypo-osmotic exposure, were used as our comparative model. Both populations could maintain osmotic homeostasis when transferred from 32 to 0.4 p.p.t., but diverged in their compensatory abilities when challenged down to …

Go to article

Trehalose Transporter From African Chironomid Larvae Improves Desiccation Tolerance Of Chinese Hamster Ovary Cells, Nilay Chakraborty, Michael A. Menze, Heidi Elmoazzen, Halong Vu, Martin L. Yarmush, Steven C. Hand, Mehmet Toner Apr 2012

Trehalose Transporter From African Chironomid Larvae Improves Desiccation Tolerance Of Chinese Hamster Ovary Cells, Nilay Chakraborty, Michael A. Menze, Heidi Elmoazzen, Halong Vu, Martin L. Yarmush, Steven C. Hand, Mehmet Toner

Faculty Publications

Dry preservation has been explored as an energy-efficient alternative to cryopreservation, but the high sensitivity of mammalian cells to desiccation stress has been one of the major hurdles in storing cells in the desiccated state. An important strategy to reduce desiccation sensitivity involves use of the disaccharide trehalose. Trehalose is known to improve desiccation tolerance in mammalian cells when present on both sides of the cell membrane. Because trehalose is membrane impermeant the development of desiccation strategies involving this promising sugar is hindered. We explored the potential of using a high-capacity trehalose transporter (TRET1) from the African chironomid Polypedilum vanderplanki …

Go to article

Louisiana Agriculture Spring, 2012 Apr 2012

Louisiana Agriculture Spring, 2012

Louisiana Agriculture

No abstract provided.

Go to article

Molecular Basis Of The Fructose-2,6-Bisphosphatase Reaction Of Pfkfb3: Transition State And The C-Terminal Function, Michael C. Cavalier, Song Gun Kim, David Neau, Yong Hwan Lee Apr 2012

Molecular Basis Of The Fructose-2,6-Bisphosphatase Reaction Of Pfkfb3: Transition State And The C-Terminal Function, Michael C. Cavalier, Song Gun Kim, David Neau, Yong Hwan Lee

Faculty Publications

The molecular basis of fructose-2,6-bisphosphatase (F-2,6-P 2ase) of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB) was investigated using the crystal structures of the human inducible form (PFKFB3) in a phospho-enzyme intermediate state (PFKFB3-P•F-6-P), in a transition state-analogous complex (PFKFB3•AlF 4), and in a complex with pyrophosphate (PFKFB3•PP i) at resolutions of 2.45, 2.2, and 2.3 Å, respectively. Trapping the PFKFB3-P•F-6-P intermediate was achieved by flash cooling the crystal during the reaction, and the PFKFB3•AlF 4 and PFKFB3•PP i complexes were obtained by soaking. The PFKFB3•AlF 4 and PFKFB3•PP i complexes resulted in removing F-6-P from the catalytic pocket. With these structures, the structures of the …

Go to article

Angiogenic Deficiency And Adipose Tissue Dysfunction Are Associated With Macrophage Malfunction In Sirt1 -/- Mice, Fen Xu, David Burk, Zhanguo Gao, Jun Yin, Xia Zhang, Jianping Weng, Jianping Ye Apr 2012

Angiogenic Deficiency And Adipose Tissue Dysfunction Are Associated With Macrophage Malfunction In Sirt1 -/- Mice, Fen Xu, David Burk, Zhanguo Gao, Jun Yin, Xia Zhang, Jianping Weng, Jianping Ye

Faculty Publications

The histone deacetylase sirtuin 1 (SIRT1) inhibits adipocyte differentiation and suppresses inflammation by targeting the transcription factors peroxisome proliferator-activated receptor γ and nuclear factor κB. Although this suggests that adiposity and inflammation should be enhanced when SIRT1 activity is inactivated in the body, this hypothesis has not been tested in SIRT1 null (SIRT1 -/-) mice. In this study, we addressed this issue by investigating the adipose tissue in SIRT1 -/-mice. Compared with their wild-type littermates, SIRT1 null mice exhibited a significant reduction in body weight. In adipose tissue, the average size of adipocytes was smaller, the content of extracellular matrix …

Go to article

Plant Science In Forest Canopies - The First 30 Years Of Advances And Challenges (1980-2010), Margaret D. Lowman, Timothy D. Schowalter Apr 2012

Plant Science In Forest Canopies - The First 30 Years Of Advances And Challenges (1980-2010), Margaret D. Lowman, Timothy D. Schowalter

Faculty Publications

Contents: Summary 12 I. Introduction 12 II. History of canopy access 13 III. Consequences of whole-tree approaches to forest science 15 IV. Canopy communities - their inhabitants, environment, and processes 16 V. The role of forest canopies in providing ecosystem services 21 VI. Using canopy science as a 'hook' to inspire forest conservation 21 VII. Conclusions -'black boxes' in canopy science that remain 22 Acknowledgements 23 References 24 Summary: As an emerging subdiscipline of forest biology, canopy science has undergone a transition from observational, 'oh-wow' exploration to a more hypothesis-driven, experimental arena for rigorous field biology. Although efforts to explore …

Go to article

Phylogenetic Relationships In Sarraceniaceae Based On Conserved Sequences Generated From Sarracenia Alata, Danielle Fuselier Apr 2012

Phylogenetic Relationships In Sarraceniaceae Based On Conserved Sequences Generated From Sarracenia Alata, Danielle Fuselier

Honors Capstones

No abstract provided.

Go to article

Phosphorylation Studies Of Serine 663 On Human 5-Lipoxygenase, Pamela Arden Doerner Apr 2012

Phosphorylation Studies Of Serine 663 On Human 5-Lipoxygenase, Pamela Arden Doerner

Honors Capstones

No abstract provided.

Go to article

Ultraconserved Elements Are Novel Phylogenomic Markers That Resolve Placental Mammal Phylogeny When Combined With Species-Tree Analysis, John E. Mccormack, Brant C. Faircloth, Nicholas G. Crawford, Patricia Adair Gowaty, Robb T. Brumfield, Travis C. Glenn Apr 2012

Ultraconserved Elements Are Novel Phylogenomic Markers That Resolve Placental Mammal Phylogeny When Combined With Species-Tree Analysis, John E. Mccormack, Brant C. Faircloth, Nicholas G. Crawford, Patricia Adair Gowaty, Robb T. Brumfield, Travis C. Glenn

Faculty Publications

Phylogenomics offers the potential to fully resolve the Tree of Life, but increasing genomic coverage also reveals conflicting evolutionary histories among genes, demanding new analytical strategies for elucidating a single history of life. Here, we outline a phylogenomic approach using a novel class of phylogenetic markers derived from ultraconserved elements and flanking DNA. Using species-tree analysis that accounts for discord among hundreds of independent loci, we show that this class of marker is useful for recovering deep-level phylogeny in placental mammals. In broad outline, our phylogeny agrees with recent phylogenomic studies of mammals, including several formerly controversial relationships. Our results …

Go to article

Genomic Insights Into Adaptation To High-Altitude Environments, Z. A. Cheviron, R. T. Brumfield Apr 2012

Genomic Insights Into Adaptation To High-Altitude Environments, Z. A. Cheviron, R. T. Brumfield

Faculty Publications

Elucidating the molecular genetic basis of adaptive traits is a central goal of evolutionary genetics. The cold, hypoxic conditions of high-altitude habitats impose severe metabolic demands on endothermic vertebrates, and understanding how high-altitude endotherms cope with the combined effects of hypoxia and cold can provide important insights into the process of adaptive evolution. The physiological responses to high-altitude stress have been the subject of over a century of research, and recent advances in genomic technologies have opened up exciting opportunities to explore the molecular genetic basis of adaptive physiological traits. Here, we review recent literature on the use of genomic …

Go to article

First Prev Next Last