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Synthesis Of Poly(L-Lactic Acid) Scaffolds From Dioxane/Ethanol Using Control Rate Freezing And Study Of Its Microstructural Properties, George Idicula Jan 2013

Synthesis Of Poly(L-Lactic Acid) Scaffolds From Dioxane/Ethanol Using Control Rate Freezing And Study Of Its Microstructural Properties, George Idicula

LSU Master's Theses

Bio-degradable poly (l-lactic acid) (PLLA) scaffolds were prepared by using thermally induced phase separation (TIPS) method. A solution of PLLA-Dioxane was formed by dissolving PLLA in dehydrated 1,4-Dioxane at three wt/vol percentages, specifically 3, 7 and 10%. This PLLA-Dioxane solution was then frozen in borosilicate glass vials (5mL) at three cooling rates (1, 10 and 40 ˚C/min) in a commercially available controlled rate freezer (CRF). The frozen solution was freeze-dried to sublimate the Dioxane. The microstructural properties of the resulting PLLA scaffolds were determined utilizing Scanning Electron Microscopy (SEM) images and uni- axial compressive testing. The relationship between the wt/vol …

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Synthesis Of The Western Hemisphere Of Theonellamide C, Saroj Yadav Jan 2013

Synthesis Of The Western Hemisphere Of Theonellamide C, Saroj Yadav

LSU Doctoral Dissertations

Theonellamides A-F were isolated from Theonella swinhoei by Fusetani and co-workers. Despite considerable synthetic effort to produce theonellamide F by the Shioiri group in the early 1990’s, the total synthesis of a theonellamide has yet to be reported. We report herein our efforts toward some of the required amino acid residues and construction of the western ring of theonellamide C. We describe the synthesis of an uncoded amino acid, (2S,4R)-ɣ-hydroxy-α-amino adipic acid (Ahad), a building block for theonellamide C. We initially investigated the Corey-Lygo method for the catalytic asymmetric generation of the Cα stereocenter. Unfortunately, the alkylation of glycine benzophenone …

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Metacognitive Awareness : Impact Of A Metacognitive Intervention In A Pre-Nursing Course, Bronwyn Perry Doyle Jan 2013

Metacognitive Awareness : Impact Of A Metacognitive Intervention In A Pre-Nursing Course, Bronwyn Perry Doyle

LSU Doctoral Dissertations

To function effectively as nurses in the evolving, complex healthcare system, nursing students must learn to be skilled thinkers, know how to learn, and know how to use what they know in novel situations. Research in the field of metacognition may offer a useful framework to improve learning and to enhance critical thinking and clinical decision-making in nursing students. The purpose of this study is to describe how pre-nursing students’ self-reported metacognitive awareness correlates with age and academic variables and to explore the effects of a metacognitive intervention on students’ metacognitive awareness. Using a quasi-experimental research design, the study consisted …

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Environmental Kuznets Curve In Water Pollution: A Semiparametric Approach, Mahesh Pandit Jan 2013

Environmental Kuznets Curve In Water Pollution: A Semiparametric Approach, Mahesh Pandit

LSU Doctoral Dissertations

The relationship between pollution and per capita income generally appears as an inverted U-shaped curve. This inverted U-shaped curve is known as the environmental Kuznets curve (EKC). The shape of the curve, however, is very sensitive to the data, location and pollutant considered in the analysis. Since the early 1990s, there has been an exponential growth in the number of empirical studies in this field, but many refute the inverted U-shaped nature of the curve for pollutants across different time periods and geographical regions. This has generated an increased interest in developing a more flexible functional form for model specification …

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Nucleic Acid Binding Thermodynamics And Functions Of Dna Polymerases, Hiromi Shimasaki Brown Jan 2013

Nucleic Acid Binding Thermodynamics And Functions Of Dna Polymerases, Hiromi Shimasaki Brown

LSU Doctoral Dissertations

This study examines several different linkages between the nucleic acid binding thermodynamics and the functions of three different DNA polymerases. The focuses are correlation of the DNA binding thermodynamics and the functional behavior of Klenow and Klentaq polymerases (from Escherichia coli and Thermus aquaticus, respectively), identification of factors that influence the proofreading activity of Klenow, and examination of HIV reverse transcriptase (HIV-RT) binding to different primer/template nucleic acid constructs. A comparison of the DNA binding thermodynamics and the incorporation activity of Klenow and Klentaq reveals that the enthalpic versus entropic balance upon binding may function as a modulator of the …

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Polymer Microsystems For The Enrichment Of Circulating Tumor Cells And Their Clinical Demonstration, Joyce W. Kamande Jan 2013

Polymer Microsystems For The Enrichment Of Circulating Tumor Cells And Their Clinical Demonstration, Joyce W. Kamande

LSU Doctoral Dissertations

Cancer research is centered on the discovery of new biomarkers that could unlock the obscurities behind the mechanisms that cause cancer or those associated with its spread (i.e., metastatic disease). Circulating tumor cells (CTCs) have emerged as attractive biomarkers for the management of many cancer-related diseases due primarily to the ease of securing them from a simple blood draw. However, their rarity (~1 CTC per mL of whole blood) makes enrichment analytically challenging. Microfluidic systems are viewed as exquisite platforms for the clinical analysis of CTCs due to their ability to be used in an automated fashion, minimizing sample loss …

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The Roles Of Deinococcus Radiodurans Dps-1 And Dps-2 In Nucleoid Organization And In Survival During Oxidative Stress, Khoa Huynh Nguyen Jan 2013

The Roles Of Deinococcus Radiodurans Dps-1 And Dps-2 In Nucleoid Organization And In Survival During Oxidative Stress, Khoa Huynh Nguyen

LSU Doctoral Dissertations

DNA protection during starvation (Dps) proteins are important for bacterial oxidative stress responses. This study aims to understand the roles and characteristics of the two Dps homologs in Deinococcus radiodurans: Dps-1 and Dps-2. Dps-2 contains a predicted signal peptide and in vivo localization of Dps-2 reveals that its location is non-cytoplasmic. β-galactosidase assays show that the Dps-2 promoter is upregulated in the presence of H2O2 and the results from the DNA protection assay show that Dps-2 is able to protect DNA efficiently against reactive oxygen species (ROS). Dps-2 has a C-terminal extension that is needed for assembly into a dodecamer …

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A Hybrid Framework Of Iterative Mapreduce And Mpi For Molecular Dynamics Applications, Shuju Bai Jan 2013

A Hybrid Framework Of Iterative Mapreduce And Mpi For Molecular Dynamics Applications, Shuju Bai

LSU Doctoral Dissertations

Developing platforms for large scale data processing has been a great interest to scientists. Hadoop is a widely used computational platform which is a fault-tolerant distributed system for data storage due to HDFS (Hadoop Distributed File System) and performs fault-tolerant distributed data processing in parallel due to MapReduce framework. It is quite often that actual computations require multiple MapReduce cycles, which needs chained MapReduce jobs. However, Design by Hadoop is poor in addressing problems with iterative structures. In many iterative problems, some invariant data is required by every MapReduce cycle. The same data is uploaded to Hadoop file system in …

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Investigation Of The Role Of Putative Inorganic Carbon Transporters In The Carbon Dioxide Concentrating Mechanisms Of Chlamydomonas Reinhardtii, Bratati Mukherjee Jan 2013

Investigation Of The Role Of Putative Inorganic Carbon Transporters In The Carbon Dioxide Concentrating Mechanisms Of Chlamydomonas Reinhardtii, Bratati Mukherjee

LSU Doctoral Dissertations

Photosynthetic microalgae optimize the utilization of inorganic carbon by active uptake and concentration of inorganic carbon (Ci) around the carbon-fixing enzyme Rubisco. This process, mostly induced under limiting carbon conditions is called the Carbon Concentrating Mechanism or CCM. The photosynthetic green alga Chlamydomonas reinhardtii serves as an excellent model organism for the study of eukaryotic CCMs. However, unlike the prokaryotic cyanobacterial CCM, which has a well-characterized Ci uptake system, the Ci uptake and transport system of the C. reinhardtii CCM is not well understood. Since CO2 is a small neutral molecule, it is believed to be able to passively diffuse …

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Molecular Phylogenetics Of The North American Snake Tribe Thamnophiini, John David Mcvay Jan 2013

Molecular Phylogenetics Of The North American Snake Tribe Thamnophiini, John David Mcvay

LSU Doctoral Dissertations

Advancements in phylogenetic theory and methodology coupled with improvements in computational and sequencing technology facilitate study of the divergence and diversification patterns of life. I apply our current understanding to further explore the relationships and evolution of the North American snake tribe Thamnophiini, as well as to address current topics in phylogenetic and taxonomic methodology. There are two paradigms for the phylogenetic analysis of multi-locus sequence data: one which forces all genes to share the same underlying history, and another that allows genes to follow idiosyncratic patterns of descent from ancestral alleles. The first of these approaches (concatenation) is a …

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Design, Synthesis, And Characterization Of Porphyrin Derivatives For Biological Applications, Raja Gabadage Waruna Eranga Jinadasa Jan 2013

Design, Synthesis, And Characterization Of Porphyrin Derivatives For Biological Applications, Raja Gabadage Waruna Eranga Jinadasa

LSU Doctoral Dissertations

Chapter 1 of this Dissertation presents a brief introduction to the basic properties of porphyrins and their derivatives (hydroporphyrins), their abundance and functions in the nature, and their applications in photodynamic therapy. Chapter 2 reports the synthesis, characterization, conformational analysis and cellular studies of novel mono conjugated regioisomers of chlorin e6 derivatives that are promising photosensitizers for photodynamic therapy. All three regioisomers were synthesized from pheophytin a, which was extracted from the alga Spirulina pacifica. In vitro investigations using human carcinoma HEp2 cells show that the 152-lysyl regioisomers accumulate the most within cells, and the most phototoxic …

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Group 3 Late Embryogenesis Abundant Proteins From Embryos Of Artemia Francisana : Molecular Characteristics, Expression And Function, Leaf Chandra Boswell Jan 2013

Group 3 Late Embryogenesis Abundant Proteins From Embryos Of Artemia Francisana : Molecular Characteristics, Expression And Function, Leaf Chandra Boswell

LSU Doctoral Dissertations

Late Embryogenesis Abundant (LEA) proteins are highly hydrophilic, intrinsically disordered proteins whose expression has been correlated with desiccation tolerance in anhydrobiotic organisms. Embryos of the brine shrimp, A. franciscana, contain high titers of group 3 LEA proteins during desiccation-tolerant stages such as diapause and pre-emergence development. Here I report the sequencing of three novel variants of AfrLEA3m mRNA (Afrlea3m_47, Afrlea3m_43 and Afrlea3m_29), whose deduced protein sequences are are predicted to localize to the mitochondrion. These mRNAs are very similar to Afrlea3m, but each has a stretch of sequence that is absent in at least one of the others. In addition …

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Development Of Watershed-Based Modeling Approach To Pollution Source Identification, Yangbin Tong Jan 2013

Development Of Watershed-Based Modeling Approach To Pollution Source Identification, Yangbin Tong

LSU Master's Theses

Identification of unknown pollution sources is essential to environmental protection and emergency response. A review of recent publications in source identification revealed that there are very limited numbers of research in modeling methods for rivers. What’s more, the majority of these attempts were to find the source strength and release time, while only a few of them discussed how to identify source locations. Comparisons of these works indicated that a combination of biological, mathematical and geographical method could effectively identify unknown source area(s), which was a more practical trial in a watershed. This thesis presents a watershed-based modeling approach to …

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Aesthetics In The Classroom For Social Justice : How Do The Theories Of John Dewey, Maxine Greene, And Jane Piirto Inform Us?, Valerie Meiners Comeaux Jan 2013

Aesthetics In The Classroom For Social Justice : How Do The Theories Of John Dewey, Maxine Greene, And Jane Piirto Inform Us?, Valerie Meiners Comeaux

LSU Doctoral Dissertations

This study asks 1) What is the relationship between art, creativity, and social justice? 2) How do the theories of John Dewey, Maxine Greene, and Jane Piirto inform our understanding of this relationship? 3) What is the role of the arts in contemporary curriculum? To answer these questions, the study chronicled the various roles of art in Western society, from Classical Greece through the present day, before exploring the aesthetic theories of Dewey, Greene, and Piirto. The findings suggest that the absence of an arts-integrated curriculum in most American public schools does not imply the absence of art programs in …

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Luminescence Studies : Part I. Lanthanide Nanogumbos Part Ii. Near Infrared Photothermal Nanogumbos, Jonathan Carver Dumke Jan 2013

Luminescence Studies : Part I. Lanthanide Nanogumbos Part Ii. Near Infrared Photothermal Nanogumbos, Jonathan Carver Dumke

LSU Doctoral Dissertations

Group of Uniform Materials Based on Organic Salts (GUMBOS) are a class of molten salts that have been focused to be specifically tailored towards applications. Primitively, from Davy to Walden molten salts were desirable for organic synthesis due to the properties. GUMBOS have been synthesized into nanoparticles (nanoGUMBOS) by various methods to be used for lanthanide luminescence and hyperthermal cancer therapeutics. Lanthanide photochemistry has been frequently studied for its high luminescence intensity, narrow emission band, and stable luminescent lifetime decay. Aerosol-derived europium nanoGUMBOS were characterized using electron microscopy (39.5 ± 8.4 nm), XPS, and spectroscopic techniques. Spectroscopic measurements indicated intense …

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The Intersection Of Motherhood And Academia As Conceptualized By Female Doctoral Students, Shaina A. Riser Jan 2013

The Intersection Of Motherhood And Academia As Conceptualized By Female Doctoral Students, Shaina A. Riser

LSU Doctoral Dissertations

The purpose of this qualitative study is to explore the attitudes of current female doctoral candidates who express an interest in pursuing a career in the professoriate, as well as express a desire to have children. The participants will explain how they conceptualize the intersection of academia and motherhood, by detailing how they negotiate and navigate their current status in as a graduate student and their future career and family goals. A limited amount of literature has been published that specifically explores the intersection of academia and motherhood as conceptualized specifically by female graduate students. Therefore, the intent of the …

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Factors Influencing Glycogen Branching Enzyme Activity In Mouse Liver, Scott Fuller Jan 2013

Factors Influencing Glycogen Branching Enzyme Activity In Mouse Liver, Scott Fuller

LSU Doctoral Dissertations

Glycogen is the storage polysaccharide in a spectrum of organisms ranging from yeast to humans. Glycogen has a highly branched structure somewhat resembling a tree or shrub, with the branch points formed by glucose molecules being joined by α 1,6-glycosidic linkages. These linkages are formed by the action of branching enzyme. Branching of glycogen is critical to health, with a lack of branching causing glycogen storage disease type IV, which is fatal in humans by age 2. While glycogen branching enzyme has been studied in clinical medicine, modulation of the enzyme has received comparatively little attention. This dissertation undertook three …

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A Feasibility Study Of Multi-Functional Wells For Water Coning Control And Disposal, Lu Jin Jan 2013

A Feasibility Study Of Multi-Functional Wells For Water Coning Control And Disposal, Lu Jin

LSU Doctoral Dissertations

Although water coning is well understood, it is difficult to control in field operations resulting in low recovery and large volumes of waste produced water. A solution - proposed here - is a multi-functional well with the in-situ bottom water drainage and injection installations - Downhole Water Loop (DWL). Theoretically, DWL greatly improves well performance (for example, a two-fold increase of DWL well’s water drainage rate would increase the critical (water-free) oil rate by 80%). However, DWL has practical limitations that must be quantified for actual well design. The objective of this work is to: (1) find maximum water drainage …

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Silica Polypeptide-Based Colloids: Physical Properties And Novel Materials, Cornelia Rosu Jan 2013

Silica Polypeptide-Based Colloids: Physical Properties And Novel Materials, Cornelia Rosu

LSU Doctoral Dissertations

The investigation of polypeptide composite particles, PCPs, is described. The production of mesoporous and polycolloid architectures is also addressed. PCPs were prepared by both growing form and grafting to method. They consist of a core made of silica, silica-coated magnetite or silica-coated cobalt. Some of the particles were covalently labeled with fluorescein isothiocyanate. Several polypeptides were chosen for attachment on the core: poly(γ-stearyl-L-glutamate), PSLG, poly(Nε-carbobenzyloxy-L-lysine), PCBL and poly(o-benzyl-L-tyrosine), PBTY. Attachment of a well-characterized alkyne-end terminated PSLG and PCBL to an azide- functionalized particle yielded PCPs with a desired sparse coverage. A blend of techniques such as FTIR, XPS, TEM, HTEM, …

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Super-Aptamer Bio-Imprinted Hydrogels : An Investigation Into The Optimization And Characterization Of Cross-Linked Polymeric Materials Displaying Macromolecular Amplified Responses, Nicholas Alexander Gariano Jan 2013

Super-Aptamer Bio-Imprinted Hydrogels : An Investigation Into The Optimization And Characterization Of Cross-Linked Polymeric Materials Displaying Macromolecular Amplified Responses, Nicholas Alexander Gariano

LSU Doctoral Dissertations

It is becoming more important to detect ultra-low concentrations of analytes for biomedical, environmental, and national security applications. Equally important is that new methods should be easy to use, inexpensive, portable, and if possible allow detection using the naked eye. Detection of low concentrations of analytes generally cannot be achieved directly, but requires signal amplification by catalysts, macromolecules, metal surfaces or supramolecular aggregates. The rapidly progressing field of macromolecular signal amplification has been advanced using conjugated polymers, chirality in polymers, solvating polymers and polymerization/depolymerization strategies. The use of molecularly imprinted polymers is ideal for creation of novel sensors to meet …

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Surface Studies Of Organic Thin Films Using Scanning Probe Microscopy And Nanofabrication, Venetia Denae Lyles Jan 2013

Surface Studies Of Organic Thin Films Using Scanning Probe Microscopy And Nanofabrication, Venetia Denae Lyles

LSU Doctoral Dissertations

Porphyrins and metalloporphyrins have unique chemical and electronic properties and thus provide useful model structures for nanoscale studies of the role of chemical structure for electronic properties. Porphyrins have been proposed as viable materials for molecular-based information-storage devices, gas sensors, photovoltaic cells, organic light-emitting diodes and molecular wires. The function and efficiency of porphyrins in devices is largely attributable to molecular architecture and how the molecules are self-organized. Modifications of the porphyrin macrocycle, peripheral groups or bound metal ions can generate a range of electrical, photoelectrical or magnetic properties. The conductive properties are greatly influenced at the molecular level by …

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The Power Of Affective Factors (Self-Efficacy, Motivation And Gender) To Predict Chemistry Achievement With The Benefits Of Knowledge Surveys On Metacognition Level, Xin Wu Jan 2013

The Power Of Affective Factors (Self-Efficacy, Motivation And Gender) To Predict Chemistry Achievement With The Benefits Of Knowledge Surveys On Metacognition Level, Xin Wu

LSU Doctoral Dissertations

Self-efficacy, gender, and motivation are subjective predictors of students' academic achievement. Self-assessment prompted by knowledge surveys involves metacognition, i.e., students' awareness of how they learn. Knowledge surveys can be used to measure changes in students' achievement level and to assist students in content review and inspire reflection on one's ability to learn. In this work, I combined the above predictors into the survey to determine whether achievement in general chemistry can be foreseen. My proposed research will be conducted on 426 students enrolled in General Chemistry I classes (Chemistry for science majors) during a regular 15-week semester at Louisiana State …

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Uncovering Nodes In The Transnational Social Networks Of Hispanic Workers, James Powell Chaney Jan 2013

Uncovering Nodes In The Transnational Social Networks Of Hispanic Workers, James Powell Chaney

LSU Doctoral Dissertations

This dissertation addresses the little studied but socially salient processes through which Latino migrant laborers find work, travel, and obtain documentation using transnational social networks spanning between their places of origin and destinations in the United States. This project focuses on the creation and maintenance of these transnational linkages with a particular interest in their expansion into locations throughout American South, the region with the highest growth rates of Hispanic populations. The aim is to understand how such migrant-labor processes influence migratory patterns and result in place creation, both in these case studies and more generally. The case studies in …

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Comparing Social Skills In Children Diagnosed With Autism Spectrum Disorders According To The Dsm-Iv-Tr And The Proposed Dsm-5, Jennifer Susan Beighley Jan 2013

Comparing Social Skills In Children Diagnosed With Autism Spectrum Disorders According To The Dsm-Iv-Tr And The Proposed Dsm-5, Jennifer Susan Beighley

LSU Master's Theses

Autism Spectrum Disorder (ASD) is currently defined using criteria from the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR). With the fifth edition of the DSM (DSM-5) forthcoming, one change the American Psychiatric Association has proposed is an increase in the number of overall symptoms necessary to meet criteria for ASD. Because social skills is well established as a core symptom of autism, the present study explores differences in social functioning using the Matson Evaluation of Social Skills in Youngsters-II (MESSY-II) in three groups of children ages 3-16 years including those diagnosed with ASD using the …

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Alu Elements And Primate Genomics, Adam Trent Mclain Jan 2013

Alu Elements And Primate Genomics, Adam Trent Mclain

LSU Doctoral Dissertations

Alu elements are a primate-specific non-autonomous retrotransposon of ~300 base pairs (bp). A Short INterspersed Element (SINE), Alu elements are found in high copy number in genomes across the primate radiation. Alu elements have a history of effective use as a phylogenetic marker due to the presence-absence nature of their retrotransposition, and have been implicated in the cause of a number of genetic diseases. Various subfamilies of Alu elements have gone through periods of increased activity during the history of the primate radiation, with the overwhelming majority of elements classified as genomic "fossils" which no longer propagate but can serve …

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Environmentally Persistent Free Radicals (Epfrs) In Pm₂.₅ : Their Contribution To Hydroxyl Radical Formation And Atmospheric Transformation, William Micheal Gehling, Jr. Jan 2013

Environmentally Persistent Free Radicals (Epfrs) In Pm₂.₅ : Their Contribution To Hydroxyl Radical Formation And Atmospheric Transformation, William Micheal Gehling, Jr.

LSU Doctoral Dissertations

Previous research demonstrated environmentally persistent free radicals (EPFRs) will form on particulate surfaces under combustion conditions (temperature range of 150-400 °C) from reactions of organic precursors with redox-active transition metals. With an understanding of how these EPFRs form, it is necessary to determine how they behave in a natural environment after emission. To better understand this, the nature of EPFRs in ambient PM2.5 under simulated atmospheric conditions was investigated. Ambient PM2.5 samples were collected at a roadside ambient monitoring site near heavy interstate traffic and major industrial activity. The EPFR concentration and general radical structure were determined with EPR spectroscopy. …

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Underwater Excavations Of Two Ancient Maya Salt Works, Paynes Creek National Park, Belize, Elizabeth Cory Sills Jan 2013

Underwater Excavations Of Two Ancient Maya Salt Works, Paynes Creek National Park, Belize, Elizabeth Cory Sills

LSU Doctoral Dissertations

Abstract Underwater excavations were conducted at an Early Classic (A.D. 300-600) and a Late Classic (A.D. 600-900) submerged ancient Maya salt works in Paynes Creek National Park, Belize. The archaeological investigations included underwater excavations, artifact analysis, marine sediment chemical testing, and source identification of obsidian—an important indicator of trade. The excavation and analysis of the salt works in Paynes Creek add a new perspective on ancient Maya craft production and the economies of other ancient civilizations. The archaeological excavations reveal activity areas associated with a substantial salt industry for distribution to the southern Maya inland inhabitants, where this biological requirement …

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Experimental And Computational Studies Of Environmentally Persistent Free Radicals (Epfrs) Formation, Lucy W. Kiruri Jan 2013

Experimental And Computational Studies Of Environmentally Persistent Free Radicals (Epfrs) Formation, Lucy W. Kiruri

LSU Doctoral Dissertations

The first part of the thesis investigates the use of theoretical quantum calculations for the study of EPFRs as the initial and fundamental step in the formation of polychlorinated dibenzo-p-dioxin and dibenzofuran. The computational model comprised of density functionals (B3LYP, PBE1PBE, and M06) and two types of basis set namely: LANL2DZ for all atoms and GEN (LANL2DZ for metals and aug-cc-pVDZ for non-metals). Full mechanisms of EPFRs formation over (CuO)1-8, and aluminum oxide clusters were studied. The most stable intermediates and products have been determined and compared to available experimental data. In case of (CuO)1-8 clusters, the small clusters are …

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A Microfluidic Bacteria Culturing Device With Maldi Mass Spectrometry Detection, Pratap Reddy Machavaram Siva Jan 2013

A Microfluidic Bacteria Culturing Device With Maldi Mass Spectrometry Detection, Pratap Reddy Machavaram Siva

LSU Master's Theses

A novel microfluidic device was developed for bacterial cell culturing using mass spectrometry as the detector. One of the challenges in proteomics is to achieve high sensitivity in the identification of proteins in complex samples with widely varying concentrations. The main limitations for proteomic studies are relatively slow and labor-intensive steps such as cell culturing and protein digestion of small sample quantities. Microfluidics is a promising approach to increase throughput and to reduce the time-consuming steps that are necessary for proteomics. When an analytical detection method is combined with microfluidics it can overcome limitations that are important in the analysis …

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Parental Perceptions Of Supportive And Non-Supportive Influences On The Development Of Leadership, Debra Jo Gifford Hailey Jan 2013

Parental Perceptions Of Supportive And Non-Supportive Influences On The Development Of Leadership, Debra Jo Gifford Hailey

LSU Doctoral Dissertations

ABSTRACT Research into young children’s leadership skills is sparse and focused on leadership in classroom contexts. Understanding of leadership development in young children can be expanded by studying parents’ perceptions of children’s leadership development as it is enacted in contexts outside of the school. The purpose of this qualitative study was to provide an examination of beliefs, practices, and contextual relationships of families with young children who were identified within their schools as having strong leadership skills. Student leaders were identified using the Leadership subscale of the Scales for Rating the Behavioral Characteristics of Superior Students--Third Edition (SRBCSS-III; Renzulli et …

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