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In-Phantom Film Measurements Of Two Treatment Planning Systems For Single-Fraction Spine Sbrt, Michael J. Taylor May 2022

In-Phantom Film Measurements Of Two Treatment Planning Systems For Single-Fraction Spine Sbrt, Michael J. Taylor

LSU Master's Theses

Purpose: Treatment planning accuracy for spine stereotactic body radiation therapy (SBRT) varies depending on the dose calculation algorithm utilized in the treatment planning system (TPS). This project compared the end-to-end accuracy between spine SBRT plans calculated in a convolution-superposition based TPS (TPSCS) and Monte Carlo based TPS (TPSMC) with radiochromic film measurements. The hypothesis was that TPSMC would calculate the dose gradient in the critical region between the vertebral body and the spinal cord more accurately than TPSCS.

Methods: Single-fraction spine SBRT treatments following RTOG 0631 and local institutional guidelines were planned in …


I'M Going Cycle Every Day, Lauren Nguyen May 2022

I'M Going Cycle Every Day, Lauren Nguyen

LSU Master's Theses

Many designers and scientists have been able to integrate design and science in their respective fields to create works that effectively inform their audiences of complicated subjects. Each of these individuals can express their creativity and viewpoint of the subject matter in a way that is interesting, visually appealing, and informative. Using the medium of graphic design, I created printed posters that represent the way I view the processes of the human body that are technical, yet also visually appealing.

My thesis exhibition walks my audience through the biological cycles that maintain the human body on an everyday basis from …


Grotesque Masculinities In The Works Of Harry Crews, Barry Hannah, And Padgett Powell, Matt Brandon Blasi May 2022

Grotesque Masculinities In The Works Of Harry Crews, Barry Hannah, And Padgett Powell, Matt Brandon Blasi

LSU Doctoral Dissertations

“Grotesque Masculinities in the Works of Harry Crews, Barry Hannah, and Padgett Powell” explores how these authors use the grotesque to complicate, distort, and criticize hegemonic white Southern masculinity as represented in contemporary American literature. In “Grotesque Masculinities,” I argue that the presence of the grotesque mode in these author’s works offers a unique critical perspective by which to better understand how masculinity is constructed by and for white Southern men in literature, and how alternative configurations of identity are not only possible, but necessary to decenter whiteness and heteronormativity as dominant categories. Using what sociologists refer to as body-reflexive …


Neural Stimulator, Jose A. Parodi Amaya, Edward F. Austin, Jin-Woo Choi May 2022

Neural Stimulator, Jose A. Parodi Amaya, Edward F. Austin, Jin-Woo Choi

Pennington Biomedical Research Center Patents

Methods and apparatus are disclosed relating to the stimulating of tissue including nerve tissue based on combinations of capacitors and resistors. Application and removal of voltage to an electrical circuit is taught as part of a method of creating voltage waveforms for nerve and other tissue with such waveforms creating neural signals. The electrical apparatus taught may, include a first electrical node grounded through a first resistor; a second electrical node grounded through a second resistor; a first capacitor connected to both the first electrical node and the second electrical node; a second capacitor separating the second electrical node from …


Sodium Mediates Developmentally Plastic Responses In Plants And Herbivores, Luis Santiago-Rosario May 2022

Sodium Mediates Developmentally Plastic Responses In Plants And Herbivores, Luis Santiago-Rosario

LSU Doctoral Dissertations

Sodium plays a crucial role in organismal performance, trophic-level interactions, and eco-evolutionary dynamics. For plants, sodium impacts osmoregulation, growth, and water uptake. For animals, sodium is essential influencing osmoregulatory processes, muscle and neural development, and blood regulation. My dissertation aims to disentangle why sodium mismatch affects resource-consumer interactions and its influence on morphological and behavioral plasticity. First, I identified how sodium impacts plant performance and sodium accumulation strategies. I initially focused my research on understanding how increasing substrate sodium affects plant growth and tissue sodium accumulation strategies in controlled settings using a systematic review approach. I found that saltier plants …


Branching Off: New Insight Into Lysosomes As Tubular Organelles, K A. Bohnert, A E. Johnson May 2022

Branching Off: New Insight Into Lysosomes As Tubular Organelles, K A. Bohnert, A E. Johnson

Faculty Publications

Lysosomes are acidic, membrane-bound organelles that play essential roles in cellular quality control, metabolism, and signaling. The lysosomes of a cell are commonly depicted as vesicular organelles. Yet, lysosomes in fact show a high degree of ultrastructural heterogeneity. In some biological contexts, lysosome membranes naturally transform into tubular, non-vesicular morphologies. Though the purpose and regulation of tubular lysosomes has been historically understudied, emerging evidence suggests that tubular lysosomes may carry out unique activities, both degradative and non-degradative, that are critical to cell behavior, function, and viability. Here, we discuss recent advances in understanding the biological significance of tubular lysosomes in …


Literacy's Levels: An Analysis Of Neoliberal Literacy Sponsorship In The U.S., Misty Dawn Fuller May 2022

Literacy's Levels: An Analysis Of Neoliberal Literacy Sponsorship In The U.S., Misty Dawn Fuller

LSU Doctoral Dissertations

While much scholarship has considered Deborah Brandt’s concept of sponsors of literacy, there remains a need to consider relationships between literacy sponsors and larger implications of literacy sponsorship at national and institutional levels. Utilizing academic theories, U.S. federal government budgets and financed reports, and discoursal analysis, this dissertation investigates literacy sponsorship at the federal, postsecondary institutional, postsecondary institutional writing programmatic, and individual levels to tease out how, and in what ways, through “enabling” and “supporting” literacy these sponsors also” regulate, suppress, and withhold literacy” (Brandt 166). Rhetorical analysis determines that, at the U.S. federal level, literacy is promoted as a …


Places To Live: A Multidisciplinary Approach To Modern Maya Houses In Yucatan, Mexico, Virginia J. Ochoa-Winemiller May 2022

Places To Live: A Multidisciplinary Approach To Modern Maya Houses In Yucatan, Mexico, Virginia J. Ochoa-Winemiller

LSU Doctoral Dissertations

In 1938, Robert C. Wauchope’s Modern Maya Houses provided the first detailed description of traditional rural housing for the Maya area. Until today, no research has attempted to test Wauchope’s notion of cultural continuity in Maya domestic architecture from the prehistoric past up to the time of his pioneering study. By examining data from three municipios located in the state of Yucatan, Mexico, I compared contemporary information collected during visits to residential areas with that published by Wauchope in 1938. An integrated approach to data gathering and analysis, that is, a combination of interviews, questionnaires, archaeological survey, and geographic information …


Evaluating The Effect Of Coated Urea And Urea-Ammonium-Nitrate Solution On Cane Tonnage, Sugar Yield, And Leaf-Soil Nitrogen Content Under Louisiana Sugarcane Production System, Hector J. Mendoza Lagos May 2022

Evaluating The Effect Of Coated Urea And Urea-Ammonium-Nitrate Solution On Cane Tonnage, Sugar Yield, And Leaf-Soil Nitrogen Content Under Louisiana Sugarcane Production System, Hector J. Mendoza Lagos

LSU Master's Theses

Nitrogen (N) is a crucial nutrient for proper plant growth and development. N deficiency results in poor tillering and thin, short internode stem production for sugarcane production, thus resulting in low cane tonnage. Therefore, proper N fertilizer management is essential for a sustainable sugarcane production system. This research was conducted at the LSU AgCenter Sugar Research Station in St. Gabriel, LA, from 2019 to 2020 at three Sites (Site 1, 2, and 3). The treatments consisted of different N rates (0, 45, 90, and 135 kg N ha-1) and sources (urea-ammonium-nitrate solution [UAN]-32%, 30-day [Coated Urea 1], 45-day …


Climate Change Impacts To The Arctic Ocean Revealed From High Resolution Geotraces 210po-210pb-226ra Disequilibria Studies, M. Baskaran, K. Krupp, W. Bam, K. Maiti May 2022

Climate Change Impacts To The Arctic Ocean Revealed From High Resolution Geotraces 210po-210pb-226ra Disequilibria Studies, M. Baskaran, K. Krupp, W. Bam, K. Maiti

Faculty Publications

Climate change is transforming the Arctic Ocean in unprecedented ways which can be most directly observed in the systematic decline in seasonal ice coverage. From the collection and analysis of particulate and dissolved activities of 210Po and 210Pb from four deepwater superstations, as a part of the US Arctic GEOTRACES cruise during 2015, and in conjunction with previously published data, the temporal and spatial variations in their activities, inventories and residence times are evaluated. The results show that the partitioning of particulate and dissolved phases has changed significantly in the 8 years between 2007 and 2015, while the …


The Heritage Family Study: A Review Of The Effects Of Exercise Training On Cardiometabolic Health, With Insights Into Molecular Transducers, Mark A. Sarzynski, Treva K. Rice, Jean Pierre Després, Louis Pérusse, Angelo Tremblay, Philip R. Stanforth, André Tchernof, Jacob L. Barber, Francesco Falciani, Clary Clish, Jeremy M. Robbins, Sujoy Ghosh, Robert E. Gerszten, Arthur S. Leon, James S. Skinner, D. C. Rao, Claude Bouchard May 2022

The Heritage Family Study: A Review Of The Effects Of Exercise Training On Cardiometabolic Health, With Insights Into Molecular Transducers, Mark A. Sarzynski, Treva K. Rice, Jean Pierre Després, Louis Pérusse, Angelo Tremblay, Philip R. Stanforth, André Tchernof, Jacob L. Barber, Francesco Falciani, Clary Clish, Jeremy M. Robbins, Sujoy Ghosh, Robert E. Gerszten, Arthur S. Leon, James S. Skinner, D. C. Rao, Claude Bouchard

Division of Basic Science Faculty Publications

The aim of the HERITAGE Family Study was to investigate individual differences in response to a standardized endurance exercise program, the role of familial aggregation, and the genetics of response levels of cardiorespiratory fitness and cardiovascular disease and diabetes risk factors. Here we summarize the findings and their potential implications for cardiometabolic health and cardiorespiratory fitness. It begins with overviews of background and planning, recruitment, testing and exercise program protocol, quality control measures, and other relevant organizational issues. A summary of findings is then provided on cardiorespiratory fitness, exercise hemodynamics, insulin and glucose metabolism, lipid and lipoprotein profiles, adiposity and …


The Energy Balance Model Of Obesity: Beyond Calories In, Calories Out, Kevin D. Hall, I. Sadaf Farooqi, Jeffery M. Friedman, Samuel Klein, Ruth J.F. Loos, David J. Mangelsdorf, Stephen O'Rahilly, Eric Ravussin, Leanne M. Redman, Donna H. Ryan, John R. Speakman, Deirdre K. Tobias May 2022

The Energy Balance Model Of Obesity: Beyond Calories In, Calories Out, Kevin D. Hall, I. Sadaf Farooqi, Jeffery M. Friedman, Samuel Klein, Ruth J.F. Loos, David J. Mangelsdorf, Stephen O'Rahilly, Eric Ravussin, Leanne M. Redman, Donna H. Ryan, John R. Speakman, Deirdre K. Tobias

Clinical Research Faculty Publications

A recent Perspective article described the "carbohydrate-insulin model (CIM)"of obesity, asserting that it "better reflects knowledge on the biology of weight control"as compared with what was described as the "dominant energy balance model (EBM),"which fails to consider "biological mechanisms that promote weight gain."Unfortunately, the Perspective conflated and confused the principle of energy balance, a law of physics that is agnostic as to obesity mechanisms, with the EBM as a theoretical model of obesity that is firmly based on biology. In doing so, the authors presented a false choice between the CIM and a caricature of the EBM that does not …


Evaluation Of Triple Negative Breast Cancer Tumor Matrix, Alejandra Ham May 2022

Evaluation Of Triple Negative Breast Cancer Tumor Matrix, Alejandra Ham

Honors Capstones

No abstract provided.


Oncostatin M Induces Lipolysis And Suppresses Insulin Response In 3t3-L1 Adipocytes, Jennifer L. Bailey, Hardy Hang, Anik Boudreau, Carrie M. Elks May 2022

Oncostatin M Induces Lipolysis And Suppresses Insulin Response In 3t3-L1 Adipocytes, Jennifer L. Bailey, Hardy Hang, Anik Boudreau, Carrie M. Elks

Division of Basic Science Faculty Publications

Oncostatin M (OSM) is an immune cell-derived cytokine that is upregulated in adipose tissue in obesity. Upon binding its receptor (OSMR), OSM induces the phosphorylation of the p66 subunit of Src homology 2 domain-containing transforming protein 1 (SHC1), called p66Shc, and activates the extracellular signal-related kinase (ERK) pathway. Mice with adipocyte-specific OSMR deletion (OsmrFKO) are insulin resistant and exhibit adipose tissue inflammation, suggesting that intact adipocyte OSM–OSMR signaling is necessary for maintaining adipose tissue health. How OSM affects specific adipocyte functions is still unclear. Here, we examined the effects of OSM on adipocyte lipolysis. We treated 3T3-L1 adipocytes with OSM, …


Hyperactivity Of A Midbrain Dopamine To 5-Ht Circuit Causes Anorexia, Hailan Liu, Xing Cai, Yanlin He, Yong Xu May 2022

Hyperactivity Of A Midbrain Dopamine To 5-Ht Circuit Causes Anorexia, Hailan Liu, Xing Cai, Yanlin He, Yong Xu

Division of Basic Science Faculty Publications

No abstract provided.


A D2 To D1 Shift In Dopaminergic Inputs To Midbrain 5-Ht Neurons Causes Anorexia In Mice, Xing Cai, Hailan Liu, Bing Feng, Meng Yu, Yang He, Hesong Liu, Chen Liang, Yongjie Yang, Longlong Tu, Nan Zhang, Lina Wang, Na Yin, Junying Han, Zili Yan, Chunmei Wang, Pingwen Xu, Qi Wu, Qingchun Tong, Yanlin He, Yong Xu May 2022

A D2 To D1 Shift In Dopaminergic Inputs To Midbrain 5-Ht Neurons Causes Anorexia In Mice, Xing Cai, Hailan Liu, Bing Feng, Meng Yu, Yang He, Hesong Liu, Chen Liang, Yongjie Yang, Longlong Tu, Nan Zhang, Lina Wang, Na Yin, Junying Han, Zili Yan, Chunmei Wang, Pingwen Xu, Qi Wu, Qingchun Tong, Yanlin He, Yong Xu

Division of Basic Science Faculty Publications

Midbrain dopamine (DA) and serotonin (5-HT) neurons regulate motivated behaviors, including feeding, but less is known about how these circuits may interact. In this study, we found that DA neurons in the mouse ventral tegmental area bidirectionally regulate the activity of 5-HT neurons in the dorsal raphe nucleus (DRN), with weaker stimulation causing DRD2-dependent inhibition and overeating, while stronger stimulation causing DRD1-dependent activation and anorexia. Furthermore, in the activity-based anorexia (ABA) paradigm, which is a mouse model mimicking some clinical features of human anorexia nervosa (AN), we observed a DRD2 to DRD1 shift of DA neurotransmission on 5-HTDRN neurons, which …


Potent Anti-Sars-Cov-2 Efficacy Of Covid-19 Hyperimmune Globulin From Vaccine-Immunized Plasma, Ding Yu, Yu Feng Li, Hong Liang, Jun Zheng Wu, Yong Hu, Yan Peng, Tao Jing Li, Ji Feng Hou, Wei Jin Huang, Li Dong Guan, Ren Han, Yan Tao Xing, Yong Zhang, Jia Liu, Lu Feng, Chun Yan Li, Xiao Long Liang, Ya Ling Ding, Zhi Jun Zhou, De Ming Ji, Fei Fei Wang, Jian Hong Yu, Kun Deng, Dong Mei Xia, De Mei Dong, Heng Rui Hu, Ya Jie Liu, Dao Xing Fu, Yan Lin He, Dong Bo Zhou, Hui Chuan Yang, Rui Jia, Chang Wen Ke, Tao Du May 2022

Potent Anti-Sars-Cov-2 Efficacy Of Covid-19 Hyperimmune Globulin From Vaccine-Immunized Plasma, Ding Yu, Yu Feng Li, Hong Liang, Jun Zheng Wu, Yong Hu, Yan Peng, Tao Jing Li, Ji Feng Hou, Wei Jin Huang, Li Dong Guan, Ren Han, Yan Tao Xing, Yong Zhang, Jia Liu, Lu Feng, Chun Yan Li, Xiao Long Liang, Ya Ling Ding, Zhi Jun Zhou, De Ming Ji, Fei Fei Wang, Jian Hong Yu, Kun Deng, Dong Mei Xia, De Mei Dong, Heng Rui Hu, Ya Jie Liu, Dao Xing Fu, Yan Lin He, Dong Bo Zhou, Hui Chuan Yang, Rui Jia, Chang Wen Ke, Tao Du

Division of Basic Science Faculty Publications

Coronavirus disease 2019 (COVID-19) remains a global public health threat. Hence, more effective and specific antivirals are urgently needed. Here, COVID-19 hyperimmune globulin (COVID-HIG), a passive immunotherapy, is prepared from the plasma of healthy donors vaccinated with BBIBP-CorV (Sinopharm COVID-19 vaccine). COVID-HIG shows high-affinity binding to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein, the receptor-binding domain (RBD), the N-terminal domain of the S protein, and the nucleocapsid protein; and blocks RBD binding to human angiotensin-converting enzyme 2 (hACE2). Pseudotyped and authentic virus-based assays show that COVID-HIG displays broad-spectrum neutralization effects on a wide variety of SARS-CoV-2 variants, …


Artemisia Dracunculus L. Ethanolic Extract And An Isolated Component, Dmc2, Ameliorate Inflammatory Signaling In Pancreatic Β-Cells Via Inhibition Of P38 Mapk, Peter Smoak, Susan J. Burke, Thomas M. Martin, Heidi M. Batdorf, Z. Elizabeth Floyd, J. Jason Collier May 2022

Artemisia Dracunculus L. Ethanolic Extract And An Isolated Component, Dmc2, Ameliorate Inflammatory Signaling In Pancreatic Β-Cells Via Inhibition Of P38 Mapk, Peter Smoak, Susan J. Burke, Thomas M. Martin, Heidi M. Batdorf, Z. Elizabeth Floyd, J. Jason Collier

Division of Basic Science Faculty Publications

Non-resolving pancreatic islet inflammation is widely viewed as a contributor to decreases in β-cell mass and function that occur in both Type 1 and Type 2 diabetes. Therefore, strategies aimed at reducing or eliminating pathological inflammation would be useful to protect islet β-cells. Herein, we described the use of 2′,4′-dihydroxy-4-methoxydihydrochalcone (DMC2), a bioactive molecule isolated from an ethanolic extract of Artemisia dracunculus L., as a novel anti-inflammatory agent. The ethanolic extract, termed PMI 5011, reduced IL-1β-mediated NF-κB activity. DMC2 retained this ability, indicating this compound as the likely source of anti-inflammatory activity within the overall PMI 5011 extract. We further …


Nams 2021 Utian Translational Science Symposium September 2021, Washington, Dc - >Charting The Path To Health In Midlife And Beyond: The Biology And Practice Of Wellness, Nanette F. Santoro, Helen L. Coons, Samar R. El Khoudary, C. Neill Epperson, Julianne Holt-Lunstad, Hadine Joffe, Sarah H. Lindsey, Kara L. Marlatt, Patti Montella, Gloria Richard-Davis, Bonny Rockette-Wagner, Marcel E. Salive, Cynthia Stuenkel, Rebecca C. Thurston, Nancy Woods, Holly Wyatt May 2022

Nams 2021 Utian Translational Science Symposium September 2021, Washington, Dc - >Charting The Path To Health In Midlife And Beyond: The Biology And Practice Of Wellness, Nanette F. Santoro, Helen L. Coons, Samar R. El Khoudary, C. Neill Epperson, Julianne Holt-Lunstad, Hadine Joffe, Sarah H. Lindsey, Kara L. Marlatt, Patti Montella, Gloria Richard-Davis, Bonny Rockette-Wagner, Marcel E. Salive, Cynthia Stuenkel, Rebecca C. Thurston, Nancy Woods, Holly Wyatt

Clinical Research Faculty Publications

Charting the Path to Health in Midlife and Beyond: The Biology and Practice of Wellness was a Translational Science Symposium held on Tuesday, September 21, 2021. Foundational psychosocial and behavioral approaches to promote healthy aging and strategies to disseminate this information were discussed. The following synopsis documents the conversation, describes the state of the science, and outlines a path forward for clinical practice. Wellness, in its broadest sense, prioritizes an orientation toward health, and an embrace of behaviors that will promote it. It involves a journey to improve and maintain physical and mental health and overall well-being to fully engage …


A Qualitative Analysis Of The Remote Food Photography Method And The Automated Self-Administered 24-Hour Dietary Assessment Tool For Assessing Children's Food Intake Reported By Parent Proxy, Traci A. Bekelman, Susan L. Johnson, Rachel I. Steinberg, Corby K. Martin, Katherine A. Sauder, Sophie Luckett-Cole, Deborah H. Glueck, Daniel S. Hsia, Dana Dabelea, P. B. Smith, K. L. Newby, D. K. Benjamin May 2022

A Qualitative Analysis Of The Remote Food Photography Method And The Automated Self-Administered 24-Hour Dietary Assessment Tool For Assessing Children's Food Intake Reported By Parent Proxy, Traci A. Bekelman, Susan L. Johnson, Rachel I. Steinberg, Corby K. Martin, Katherine A. Sauder, Sophie Luckett-Cole, Deborah H. Glueck, Daniel S. Hsia, Dana Dabelea, P. B. Smith, K. L. Newby, D. K. Benjamin

Clinical Research Faculty Publications

Background: Accuracy and participant burden are two key considerations in the selection of a dietary assessment tool for assessing children's full-day dietary intake. Objective: The aim of this study was to identify barriers experienced by parents and burden when using two technology-based measures of dietary intake to report their child's intake: the Remote Food Photography Method (RFPM) and the Automated Self-Administered 24-hour Dietary Assessment Tool (ASA24). Design: Qualitative, semistructured, focus groups were conducted with parents who served as proxy reporters of their child's dietary intake using the two different dietary assessment methods (ie, RFPM and ASA24) 1 week apart. Participants/setting: …


State Of Ex Situ Conservation Of Landrace Groups Of 25 Major Crops, Julian Ramirez-Villegas, Colin K. Khoury, Harold A. Achicanoy, Maria Victoria Diaz, Andres C. Mendez, Chrystian C. Sosa, Zakaria Kehel, Luigi Guarino, Michael Abberton, Jorrel Aunario, Bashir Al Awar, Juan Carlos Alarcon, Ahmed Amri, Noelle L. Anglin, Vania Azevedo, Khadija Aziz, Grace Lee Capilit, Oswaldo Chavez, Dmytro Chebotarov, Denise E. Costich, Daniel G. Debouck, David Ellis, Hamidou Falalou, Albert Fiu, Michel Edmond Ghanem, Peter Giovannini, Alphonse J. Goungoulou, Badara Gueye, Amal Ibn El Hobyb, Ramni Jamnadass, Chris S. Jones, Bienvenu Kpeki, Jae Sung Lee May 2022

State Of Ex Situ Conservation Of Landrace Groups Of 25 Major Crops, Julian Ramirez-Villegas, Colin K. Khoury, Harold A. Achicanoy, Maria Victoria Diaz, Andres C. Mendez, Chrystian C. Sosa, Zakaria Kehel, Luigi Guarino, Michael Abberton, Jorrel Aunario, Bashir Al Awar, Juan Carlos Alarcon, Ahmed Amri, Noelle L. Anglin, Vania Azevedo, Khadija Aziz, Grace Lee Capilit, Oswaldo Chavez, Dmytro Chebotarov, Denise E. Costich, Daniel G. Debouck, David Ellis, Hamidou Falalou, Albert Fiu, Michel Edmond Ghanem, Peter Giovannini, Alphonse J. Goungoulou, Badara Gueye, Amal Ibn El Hobyb, Ramni Jamnadass, Chris S. Jones, Bienvenu Kpeki, Jae Sung Lee

Faculty Publications

Crop landraces have unique local agroecological and societal functions and offer important genetic resources for plant breeding. Recognition of the value of landrace diversity and concern about its erosion on farms have led to sustained efforts to establish ex situ collections worldwide. The degree to which these efforts have succeeded in conserving landraces has not been comprehensively assessed. Here we modelled the potential distributions of eco-geographically distinguishable groups of landraces of 25 cereal, pulse and starchy root/tuber/fruit crops within their geographic regions of diversity. We then analysed the extent to which these landrace groups are represented in genebank collections, using …


Variation And Predictors Of Gross Motor Coordination Development In Azorean Children: A Quantile Regression Approach, Sara Pereira, Flávio Bastos, Carla Santos, José Maia, Go Tani, Leah E. Robinson, Peter T. Katzmarzyk May 2022

Variation And Predictors Of Gross Motor Coordination Development In Azorean Children: A Quantile Regression Approach, Sara Pereira, Flávio Bastos, Carla Santos, José Maia, Go Tani, Leah E. Robinson, Peter T. Katzmarzyk

Population and Public Health Science Faculty Publications

We investigated the development of gross motor coordination (GMC) as well as its predictors in school-aged Azorean children. The sample included 181 children (90 girls), followed consecutively for 4 years from 6 to 9 years of age. GMC was assessed with the Körperkoordination-stest für Kinder, and predictors included body mass index, standing long jump, 50-yard dash, and shuttle run. The changes in GMC and the effects of predictors were analyzed with mean-modeling as well as quantile regression. In the latter, we considered the following three quantiles (Q): Q20, Q50, and Q80 as markers of low, median, and high GMC levels, …


Sibling Resemblances In Physical Fitness In Three Distinct Regions In Peru: The Peruvian Sibling Study On Growth And Health, Carla Santos, Alcibíades Bustamante, Olga Vasconcelos, Sara Pereira, Rui Garganta, J. Timothy Lightfoot, Go Tani, Donald Hedeker, Peter T. Katzmarzyk, José Maia May 2022

Sibling Resemblances In Physical Fitness In Three Distinct Regions In Peru: The Peruvian Sibling Study On Growth And Health, Carla Santos, Alcibíades Bustamante, Olga Vasconcelos, Sara Pereira, Rui Garganta, J. Timothy Lightfoot, Go Tani, Donald Hedeker, Peter T. Katzmarzyk, José Maia

Population and Public Health Science Faculty Publications

We estimated sibling resemblance in health-related physical fitness (PF) and examined how individual characteristics and shared natural environment accounted for sibling similarities. The sample comprised 656 sibling pairs and 102 triplets (6–15 years of age), from three geographical areas of Peru. PF components included morphological (waist circumference, sum of skinfolds), muscular (handgrip strength, standing long jump), and motor (shuttle-run). Body mass index (BMI) and somatic maturation were also assessed. In general, sibling intraclass correlations differed significantly across sib-ship types for waist circumference and handgrip strength but were the same for sum of skinfolds, standing long jump, and shuttle-run. Further, in …


Regional Variation In Growth Status. The Peruvian Health And Optimist Growth Study, Alcibíades Bustamante, Carla Santos, Sara Pereira, Duarte Freitas, Peter T. Katzmarzyk, José Maia May 2022

Regional Variation In Growth Status. The Peruvian Health And Optimist Growth Study, Alcibíades Bustamante, Carla Santos, Sara Pereira, Duarte Freitas, Peter T. Katzmarzyk, José Maia

Population and Public Health Science Faculty Publications

Objective: This study aims to (1) investigate differences in weight, body mass index (BMI), and waist circumference (WC) among Peruvian children and adolescents living in three areas located at different altitudes; (2) compare age- and sex-specific height, weight, and BMI within each site with US reference data. Methods: We sampled 8753 subjects (4130 boys), aged 4 to 17 years from sea level, rainforest, and high-altitude. Height, weight, and WC were measured and BMI was calculated. Analysis of variance was used to compare variables across geographic regions, and the Hoff and Blackburn procedure was used to compare the Peruvian results with …


Expression Of Arylamine N-Acetyltransferase 2 Activity In Immortalized Human Bronchial Epithelial Cells, James T.F. Wise, Raúl A. Salazar-González, Mariam R. Habil, Mark A. Doll, David W. Hein May 2022

Expression Of Arylamine N-Acetyltransferase 2 Activity In Immortalized Human Bronchial Epithelial Cells, James T.F. Wise, Raúl A. Salazar-González, Mariam R. Habil, Mark A. Doll, David W. Hein

Faculty Publications

Lung cancer is the leading cause of cancer deaths in the United States with high incidence in tobacco smokers. Arylamine N-acetyltransferase 2 (NAT2) is a xenobiotic enzyme that catalyzes both N- and O-acetylation of carcinogens present in tobacco smoke and contributes towards the genotoxicity of these carcinogens. NAT2 allelic variants result in slow, intermediate, and rapid acetylation phenotypes. A recent meta-analysis reported NAT2 non-rapid (slow and intermediate) phenotypes had a significantly increased risk of lung cancer. NAT2 activity in humans is thought to be restricted to liver and gastrointestinal tract, and no studies to our knowledge have reported the expression …


A Reappraisal Of Polyploidy Events In Grasses (Poaceae) In A Rapidly Changing World, Acga Cheng, Noraikim Mohd Hanafiah, Jennifer Ann Harikrishna, Niranjan Baisakh, Muhamad Shakirin Mispan, Lim Phaik Eem May 2022

A Reappraisal Of Polyploidy Events In Grasses (Poaceae) In A Rapidly Changing World, Acga Cheng, Noraikim Mohd Hanafiah, Jennifer Ann Harikrishna, Niranjan Baisakh, Muhamad Shakirin Mispan, Lim Phaik Eem

Faculty Publications

Around 80% of megaflora species became extinct at the Cretaceous–Paleogene (K–Pg) boundary. Subsequent polyploidy events drove the survival of thousands of plant species and played a significant historical role in the development of the most successful modern cereal crops. However, current and rapid global temperature change poses an urgent threat to food crops worldwide, including the world’s big three cereals: rice, wheat, and maize, which are members of the grass family, Poaceae. Some minor cereals from the same family (such as teff) have grown in popularity in recent years, but there are important knowledge gaps regarding the similarities and differences …


Mhealth Intervention For Motor Skills: A Randomized Controlled Trial, Amanda E. Staiano, Robert L. Newton, Robbie A. Beyl, Chelsea L. Kracht, Chelsea A. Hendrick, Matthew Viverito, E. Kipling Webster May 2022

Mhealth Intervention For Motor Skills: A Randomized Controlled Trial, Amanda E. Staiano, Robert L. Newton, Robbie A. Beyl, Chelsea L. Kracht, Chelsea A. Hendrick, Matthew Viverito, E. Kipling Webster

Population and Public Health Science Faculty Publications

BACKGROUND AND OBJECTIVES: Children's motor skills are a critical foundation for physical activity. The objective was to determine the effectiveness and feasibility of a mobile app-based intervention delivered to parents to improve preschoolers’ motor skills. METHODS: This randomized controlled trial randomly assigned children to: (1) Motor Skills, including instructional lessons, peer modeling videos, behavioral scaffolding, and structured activities or 2) Free Play. Both groups received a 12-week app-based intervention informed by social cognitive theory to deliver 12 hours (12-minutes per day, 5× per week) of instruction. The children were aged 3 to 5 y; parents and children had no mobility …


Bridging The Research Gap Between Live Collections In Zoos And Preserved Collections In Natural History Museums, Sinlan Poo, Steven M. Whitfield, Alexander Shepack, Gregory J. Watkins-Colwell, Gil Nelson, Jillian Goodwin, Allison Bogisich, Patricia L.R. Brennan, Jennifer D'Agostino, Michelle S. Koo, Joseph R. Mendelson, Rebecca Snyder, Sandra Wilson, Gary P. Aronsen, Andrew C. Bentley, David C. Blackburn, Matthew R. Borths, Mariel L. Campbell, Dalia A. Conde, Joseph A. Cook, Juan D. Daza, Daniel P. Dembiec, Jonathan L. Dunnum, Catherine M. Early, Adam W. Ferguson, Amanda Greene, Robert Guralnick, Courtney Janney, Debbie Johnson, Felicia Knightly, Stephane Poulin, Luiz Rocha, Pamela S. Soltis May 2022

Bridging The Research Gap Between Live Collections In Zoos And Preserved Collections In Natural History Museums, Sinlan Poo, Steven M. Whitfield, Alexander Shepack, Gregory J. Watkins-Colwell, Gil Nelson, Jillian Goodwin, Allison Bogisich, Patricia L.R. Brennan, Jennifer D'Agostino, Michelle S. Koo, Joseph R. Mendelson, Rebecca Snyder, Sandra Wilson, Gary P. Aronsen, Andrew C. Bentley, David C. Blackburn, Matthew R. Borths, Mariel L. Campbell, Dalia A. Conde, Joseph A. Cook, Juan D. Daza, Daniel P. Dembiec, Jonathan L. Dunnum, Catherine M. Early, Adam W. Ferguson, Amanda Greene, Robert Guralnick, Courtney Janney, Debbie Johnson, Felicia Knightly, Stephane Poulin, Luiz Rocha, Pamela S. Soltis

Faculty Publications

Zoos and natural history museums are both collections-based institutions with important missions in biodiversity research and education. Animals in zoos are a repository and living record of the world's biodiversity, whereas natural history museums are a permanent historical record of snapshots of biodiversity in time. Surprisingly, despite significant overlap in institutional missions, formal partnerships between these institution types are infrequent. Life history information, pedigrees, and medical records maintained at zoos should be seen as complementary to historical records of morphology, genetics, and distribution kept at museums. Through examining both institution types, we synthesize the benefits and challenges of cross-institutional exchanges …


Paraphyletic Relationships Revealed By Mitochondrial Dna In The Peromyscus Mexicanus Species Group (Rodentia: Cricetidae), Giovani Hernández-Canchola, Livia León-Paniagua, Jacob A. Esselstyn May 2022

Paraphyletic Relationships Revealed By Mitochondrial Dna In The Peromyscus Mexicanus Species Group (Rodentia: Cricetidae), Giovani Hernández-Canchola, Livia León-Paniagua, Jacob A. Esselstyn

Faculty Publications

Although deer mice (Peromyscus spp.) are among the most studied small mammals, their species diversity and phylogenetic relationships remain unclear. The lack of taxonomic clarity is mainly due to a conservative morphology and because some taxa are rare, have restricted distributions, or are poorly sampled. One taxon, P. mexicanus, includes southern Mexican subspecies that have not had their systematic placement tested with genetic data. We analyzed the phylogenetic relationships and genetic structure of P. mexicanus populations using sequences of the mitochondrial gene cytochrome b. We inferred that P. mexicanus is paraphyletic, with P. m. teapensis, P. m. tehuantepecus, and P. …


Value-Added Utilization Of Wheat Straw: From Cellulose And Cellulose Nanofiber To All-Cellulose Nanocomposite Film, Hongxia Bian, Yanyan Yang, Peng Tu, Jonathan Y. Chen May 2022

Value-Added Utilization Of Wheat Straw: From Cellulose And Cellulose Nanofiber To All-Cellulose Nanocomposite Film, Hongxia Bian, Yanyan Yang, Peng Tu, Jonathan Y. Chen

Faculty Publications

To accelerate the high value-added usage of agricultural residue, cellulose and cellulose nanofibers (CNFs) were extracted from wheat straw and then formed into all-cellulose nanocomposite films. The acid–alkali method (AM) and the extraction method (EM) were respectively adopted to prepare wheat straw cellulose (WSC), and the TEMPO oxidation method was used to extract CNFs. The nanocomposite films were fabricated by dissolving WSC and adding different CNF contents of 0.0, 0.5, 1.5, and 3.0%. There was a better miscibility for the all-cellulose nanocomposite film prepared by EM (Composite-E) compared to that for the all-cellulose nanocomposite film prepared by AM (Composite-A). Composite-E …