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Insurance Coverage And Flood Exposure In The Gulf Of Mexico Region: Risk, Social Vulnerability, Urban Form, And Scale, Anissa J. Hyde Aug 2024

Insurance Coverage And Flood Exposure In The Gulf Of Mexico Region: Risk, Social Vulnerability, Urban Form, And Scale, Anissa J. Hyde

LSU Master's Theses

Increasing flood losses in the Gulf of Mexico pose serious threats to resilience and insurability. The purpose of this study is to understand how scale, social vulnerability, risk and urban form relate to NFIP insurance coverage and flood exposure. Our multilevel models identify that flooding is significantly clustered by region and counties, especially shoreline counties. Our measures of risk suggest that the FEMA Special Flood Hazard Areas underestimates risk and exposure when compared with Flood Factor, and that there is some compensation in terms of insurance coverage, suggesting a pattern of adverse selection. Older housing stock appears both less insured …


Analysis Of Traffic Operation And Safety At Cloverleaf And Diamond Interchanges With And Without Connected And Autonomous Vehicles, Nischal Khadka Aug 2024

Analysis Of Traffic Operation And Safety At Cloverleaf And Diamond Interchanges With And Without Connected And Autonomous Vehicles, Nischal Khadka

LSU Master's Theses

Even though diamond and cloverleaf interchanges are commonly used in road networks, comparative studies on their operational safety and efficiency remain limited. Also, previous studies have explored the impact of Connected and Autonomous Vehicles (CAVs) at diamond interchanges, but the effects on cloverleaf interchanges are not yet thoroughly investigated. This study addresses these gaps by evaluating the traffic operation and safety performance of cloverleaf interchanges compared to diamond interchanges. It also assesses the influence of various Market Penetration Rates (MPRs) of CAVs on travel time, queue lengths, and conflict points at cloverleaf interchanges, considering different weaving lengths.

Data on peak-hour …


Trends In Hot Carrier Distribution For Disordered Noble-Transition Metal Alloys, Eklavya Thareja, Kevin M. Mcpeak, Phillip T. Sprunger, Ilya Vekhter, William A. Shelton Aug 2024

Trends In Hot Carrier Distribution For Disordered Noble-Transition Metal Alloys, Eklavya Thareja, Kevin M. Mcpeak, Phillip T. Sprunger, Ilya Vekhter, William A. Shelton

Faculty Publications

We developed and tested an approach for predicting trends for efficient hot carrier generation among disordered metal alloys. We provide a simple argument for the importance of indirect transitions in the presence of disorder, thus justifying the use of joint density of states (JDOS)-like quantities for exploring these trends. We introduce a new JDOS-like quantity, JDOSK , which heuristically accounts for longer lifetimes of quasiparticles close to the Fermi energy. To demonstrate the efficacy of this new quantity, we apply it to the study of Cu50X50 where X = Ag, Au, Pd and Y50Pd50 where Y = Au, Ni. We …


Photoactivated Cyclic Polyphthalaldehyde Microcapsules For Payload Delivery, Youngsu Shin, Jared M. Schwartz, Anthony C. Engler, Brad Jones, Oleg Davydovich, Paul A. Kohl Aug 2024

Photoactivated Cyclic Polyphthalaldehyde Microcapsules For Payload Delivery, Youngsu Shin, Jared M. Schwartz, Anthony C. Engler, Brad Jones, Oleg Davydovich, Paul A. Kohl

Faculty Publications

Microcapsules with a cyclic polyphthalaldehyde (cPPA) shell and oil core were fabricated by an emulsification process. The low ceiling temperature cPPA shell was made phototriggerable by incorporating a photoacid generator (PAG). Photoactivation of the PAG created a strong acid which catalyzed cPPA depolymerization, resulting in the release of the core payload, as quantified by 1H NMR. The high molecular weight cPPA (197 kDa) yielded uniform spherical microcapsules. The core diameter was 24.8 times greater than the cPPA shell thickness (2.4 to 21.6 μm). Nonionic bis(cyclohexylsulfonyl)diazomethane (BCSD) and N-hydroxynaphthalimide triflate (HNT) PAGs were used as the PAG in the microcapsule shells. …


Improving Bovine Intracytoplasmic Sperm Injection, Lauren Gatenby Aug 2024

Improving Bovine Intracytoplasmic Sperm Injection, Lauren Gatenby

LSU Doctoral Dissertations

Despite large efforts, there has been minimal improvements in bovine intracytoplasmic sperm injection (ICSI) in the last few decades. In this study, we investigate methods to improve embryo development rates with ICSI in cattle through addressing sperm and oocyte factors and modifying injection methods. Inducing the acrosome reaction in bull sperm prior to injection with progesterone increased cleavage (46.2% vs 16.2%) and blastocyst (21% vs 3.8%) rates compared to controls, respectively. Supplementing glutathione during in vitro maturation of the oocyte did reduce free reactive oxygen species (ROS) in the oocyte, but did not improve embryo development rates with ICSI or …


A Coarse-Grained Molecular Dynamics Study Of Gas Hydrate Formation And Dissociation, Meisam Adibifard Aug 2024

A Coarse-Grained Molecular Dynamics Study Of Gas Hydrate Formation And Dissociation, Meisam Adibifard

LSU Doctoral Dissertations

The study of gas hydrates has increased significantly over the last two decades because of their potential application in energy storage, production and transportation, water desalination, refrigeration, gas separation, etc. There is a significant interest in commercially developing natural gas hydrates because the energy content of methane hydrate reservoirs (MHRs) is at least twice that of all conventional fossil fuels combined. Additionally, due to the higher storage capacity of hydrates, it is proposed to sequester CO2 in the form of CO2 hydrate, thereby reducing the amount of greenhouse gases. Hence, hydrates offer a dual solution to two of …


A Comparison Of Diploid And Triploid Eastern Oysters For Aquaculture Production Under Extreme Temperatures And Salinities, Joshua H. Kim Aug 2024

A Comparison Of Diploid And Triploid Eastern Oysters For Aquaculture Production Under Extreme Temperatures And Salinities, Joshua H. Kim

LSU Master's Theses

Off-bottom aquaculture of Eastern oysters (Crassostrea virginica) is a nascent industry that is increasingly supported by the use of triploid oysters, which grow faster than diploids. Despite their growth advantage, elevated triploid mortality compared to diploids under high temperature, low salinity, or a combination of these conditions challenge consistent triploid production. Identifying the environmental thresholds at which differential triploid mortality occurs and predicting its economic impact are important to informing decision-making in oyster aquaculture. The goal of this thesis was to compare the biological and economic performance of diploid and triploid oysters under high temperature and low salinity conditions. …


International Consensus On Fasting Terminology, Daniela A. Koppold, Carolin Breinlinger, Etienne Hanslian, Christian Kessler, Holger Cramer, Anika Rajput Khokhar, Courtney M. Peterson, Grant Tinsley, Claudio Vernieri, Richard J. Bloomer, Michael Boschmann, Nicola L. Bragazzi, Sebastian Brandhorst, Kelsey Gabel, Alan C. Goldhamer, Martin M. Grajower, Michelle Harvie, Leonie Heilbronn, Benjamin D. Horne, Spyridon N. Karras, Jost Langhorst, Eva Lischka, Frank Madeo, Sarah J. Mitchell, Ioannis Eleemon Papagiannopoulos-Vatopaidinos, Maria Papagiannopoulou, Hanno Pijl, Eric Ravussin, Martha Ritzmann-Widderich, Krista Varady, Lilian Adamidou, Melika Chihaoui, Rafael De Cabo, Mohamed Hassanein Aug 2024

International Consensus On Fasting Terminology, Daniela A. Koppold, Carolin Breinlinger, Etienne Hanslian, Christian Kessler, Holger Cramer, Anika Rajput Khokhar, Courtney M. Peterson, Grant Tinsley, Claudio Vernieri, Richard J. Bloomer, Michael Boschmann, Nicola L. Bragazzi, Sebastian Brandhorst, Kelsey Gabel, Alan C. Goldhamer, Martin M. Grajower, Michelle Harvie, Leonie Heilbronn, Benjamin D. Horne, Spyridon N. Karras, Jost Langhorst, Eva Lischka, Frank Madeo, Sarah J. Mitchell, Ioannis Eleemon Papagiannopoulos-Vatopaidinos, Maria Papagiannopoulou, Hanno Pijl, Eric Ravussin, Martha Ritzmann-Widderich, Krista Varady, Lilian Adamidou, Melika Chihaoui, Rafael De Cabo, Mohamed Hassanein

Clinical Research Faculty Publications

Although fasting is increasingly applied for disease prevention and treatment, consensus on terminology is lacking. Using Delphi methodology, an international, multidisciplinary panel of researchers and clinicians standardized definitions of various fasting approaches in humans. Five online surveys and a live online conference were conducted with 38 experts, 25 of whom completed all 5 surveys. Consensus was achieved for the following terms: “fasting” (voluntary abstinence from some or all foods or foods and beverages), “modified fasting” (restriction of energy intake to max. 25% of energy needs), “fluid-only fasting,” “alternate-day fasting,” “short-term fasting” (lasting 2–3 days), “prolonged fasting” (≥4 consecutive days), and …


Maternal Serum Branched-Chain Amino Acids In Early Pregnancy And Offspring Growth Patterns From 1 Year To 8 Years Of Age, Ninghua Li, Junhong Leng, Rui Zhang, Hui Wang, Weiqin Li, Shuang Zhang, Yijuan Qiao, Jing Li, Zhijie Yu, Gang Hu, Zhongze Fang, Xilin Yang Aug 2024

Maternal Serum Branched-Chain Amino Acids In Early Pregnancy And Offspring Growth Patterns From 1 Year To 8 Years Of Age, Ninghua Li, Junhong Leng, Rui Zhang, Hui Wang, Weiqin Li, Shuang Zhang, Yijuan Qiao, Jing Li, Zhijie Yu, Gang Hu, Zhongze Fang, Xilin Yang

Population and Public Health Science Faculty Publications

No abstract provided.


Why Are There So Many Definitions Of Eutrophication?, Alexandrine Pannard, Philippe Souchu, Christian Chauvin, Monique Delabuis, Chantal Gascuel-Odoux, Erik Jeppesen, Morgane Le Moal, Alain Ménesguen, Gilles Pinay, Nancy N. Rabalais, Yves Souchon, Elisabeth M. Gross Aug 2024

Why Are There So Many Definitions Of Eutrophication?, Alexandrine Pannard, Philippe Souchu, Christian Chauvin, Monique Delabuis, Chantal Gascuel-Odoux, Erik Jeppesen, Morgane Le Moal, Alain Ménesguen, Gilles Pinay, Nancy N. Rabalais, Yves Souchon, Elisabeth M. Gross

Faculty Publications

Because of the first observations in the 1900s of the oligotrophic and eutrophic states of lakes, researchers have been interested in the process that makes lakes become turbid because of high phytoplankton biomass. Definitions of eutrophication have multiplied and diversified since the mid-20th century, more than for any other ecological process. Reasons for the high number of definitions might be that the former ones did not sufficiently describe their causes and/or consequences. Global change is bringing eutrophication more into the spotlight than ever, highlighting the need to find consensus on a common definition, or at least to explain and clarify …


Key Uncertainties And Modeling Needs For Managing Living Marine Resources In The Future Arctic Ocean, Julia G. Mason, Andrea Bryndum-Buchholz, Juliano Palacios-Abrantes, Renuka Badhe, Isabella Morgante, Daniele Bianchi, Julia L. Blanchard, Jason D. Everett, Cheryl S. Harrison, Ryan F. Heneghan, Camilla Novaglio, Colleen M. Petrik Aug 2024

Key Uncertainties And Modeling Needs For Managing Living Marine Resources In The Future Arctic Ocean, Julia G. Mason, Andrea Bryndum-Buchholz, Juliano Palacios-Abrantes, Renuka Badhe, Isabella Morgante, Daniele Bianchi, Julia L. Blanchard, Jason D. Everett, Cheryl S. Harrison, Ryan F. Heneghan, Camilla Novaglio, Colleen M. Petrik

Faculty Publications

Emerging fishing activity due to melting ice and poleward species distribution shifts in the rapidly-warming Arctic Ocean challenges transboundary management and requires proactive governance. A 2021 moratorium on commercial fishing in the Arctic high seas provides a 16-year runway for improved scientific understanding. Given substantial knowledge gaps, characterizing areas of highest uncertainty is a key first step. Marine ecosystem model ensembles that project future fish distributions could inform management of future Arctic fisheries, but Arctic-specific variation has not yet been examined for global ensembles. We use the Fisheries and Marine Ecosystem Intercomparison Project ensemble driven by two Earth System Models …


State Of The Science On Brain Insulin Resistance And Cognitive Decline Due To Alzheimer's Disease, Elizabeth M. Rhea, Manon Leclerc, Hussein N. Yassine, Ana W. Capuano, Han Tong, Vladislav A. Petyuk, Shannon L. Macauley, Xavier Fioramonti, Owen Carmichael, Frederic Calon, Zoe Arvanitakis Aug 2024

State Of The Science On Brain Insulin Resistance And Cognitive Decline Due To Alzheimer's Disease, Elizabeth M. Rhea, Manon Leclerc, Hussein N. Yassine, Ana W. Capuano, Han Tong, Vladislav A. Petyuk, Shannon L. Macauley, Xavier Fioramonti, Owen Carmichael, Frederic Calon, Zoe Arvanitakis

Clinical Research Faculty Publications

Type 2 diabetes mellitus (T2DM) is common and increasing in prevalence worldwide, with devastating public health consequences. While peripheral insulin resistance is a key feature of most forms of T2DM and has been investigated for over a century, research on brain insulin resistance (BIR) has more recently been developed, including in the context of T2DM and non-diabetes states. Recent data support the presence of BIR in the aging brain, even in non-diabetes states, and found that BIR may be a feature in Alzheimer's disease (AD) and contributes to cognitive impairment. Further, therapies used to treat T2DM are now being investigated …


Recreational Cannabis In Louisiana: Anticipating Potential Risks For Motor Vehicle Safety In The Short And Long Term, Aimee H. Moles, Andrew Burns, Ashley Tillison, Austin L. Matthews Aug 2024

Recreational Cannabis In Louisiana: Anticipating Potential Risks For Motor Vehicle Safety In The Short And Long Term, Aimee H. Moles, Andrew Burns, Ashley Tillison, Austin L. Matthews

Reports

This document, titled Recreational Cannabis in Louisiana: Anticipating Potential Risks for Motor Vehicle Safety in the Short and Long Term, provides a comprehensive analysis of the potential impacts that cannabis legalization could have on road safety in Louisiana. The document is written to equip policymakers and concerned citizens with the necessary knowledge to navigate the complex landscape of cannabis legalization and its implications for public safety.

Key Objectives and Scope: The primary purpose of this document is to evaluate the potential risks associated with recreational cannabis legalization on motor vehicle safety, drawing on data and experiences from Canada and states …


Solubilization Of Paclitaxel With Natural Compound Rubusoside Toward Improving Oral Bioavailability In A Rodent Model, Jian Zhang, Jicheng Shu, Rhett W. Stout, Paul S. Russo, Zhijun Liu Aug 2024

Solubilization Of Paclitaxel With Natural Compound Rubusoside Toward Improving Oral Bioavailability In A Rodent Model, Jian Zhang, Jicheng Shu, Rhett W. Stout, Paul S. Russo, Zhijun Liu

Faculty Publications

Paclitaxel, which features low water solubility and permeability, is an efflux pump substrate. The current paclitaxel drugs are given intravenously after resolving the solubility issue. Yet, oral delivery to achieve therapeutic bioavailability is not effective due to low absorption. This study evaluated a natural compound, rubusoside, to improve oral bioavailability in an animal model. Free paclitaxel molecules were processed into nano-micelles formed in water with rubusoside. The particle size of the nano-micelles in water was determined using dynamic light scattering. The oral bioavailability of paclitaxel in nano-micelles was determined against Cremophor/alcohol-solubilized Taxol after oral and intravenous administration to pre-cannulated Sprague …


The Evolution Of Science And Regulation Of Dietary Supplements: Past, Present, And Future, Paul M. Coates, Regan L. Bailey, Jeffrey B. Blumberg, Ahmed El-Sohemy, Elizabeth Floyd, Joshua Z. Goldenberg, Aimée Gould Shunney, Hannah D. Holscher, Yasmeen Nkrumah-Elie, Deshanie Rai, Barry W. Ritz, Wendy J. Weber Aug 2024

The Evolution Of Science And Regulation Of Dietary Supplements: Past, Present, And Future, Paul M. Coates, Regan L. Bailey, Jeffrey B. Blumberg, Ahmed El-Sohemy, Elizabeth Floyd, Joshua Z. Goldenberg, Aimée Gould Shunney, Hannah D. Holscher, Yasmeen Nkrumah-Elie, Deshanie Rai, Barry W. Ritz, Wendy J. Weber

Division of Basic Science Faculty Publications

Dietary supplement use in the United States is widespread and increasing, especially among certain population groups, such as older Americans. The science surrounding dietary supplements has evolved substantially over the last few decades since their formal regulation in 1994. Much has been learned about the mechanisms of action of many dietary supplement ingredients, but the evidence on their health effects is still building. As is true of much nutrition research, there are many studies that point to health effects, but not all are at the level of scientific evidence (e.g., randomized controlled interventions), rigor, or quality needed for definitive statements …


The Impact Of Obesity On Reproductive Health And Metabolism In Reproductive-Age Females, Samantha B. Schon, Hannah E. Cabre, Leanne M. Redman Aug 2024

The Impact Of Obesity On Reproductive Health And Metabolism In Reproductive-Age Females, Samantha B. Schon, Hannah E. Cabre, Leanne M. Redman

Clinical Research Faculty Publications

Obesity is a highly prevalent chronic disease that impacts >40% of reproductive-aged females. The pathophysiology of obesity is complex and can be understood simply as a chronic energy imbalance whereby caloric intake exceeds caloric expenditure with an energy surplus stored in adipose tissue. Obesity may be categorized into degrees of severity as well as different phenotypes on the basis of metabolic health and underlying pathophysiology. Obesity and excess adiposity have a significant impact on fertility and reproductive health, with direct effects on the hypothalamic-pituitary-ovarian axis, the ovary and oocyte, and the endometrium. There are significant adverse pregnancy outcomes related to …


Changes In Energy Expenditure And Physical Activity Over 15 Years Of Environmental Changes: The Maycoba Project, Alexandra Niclou, Julián Esparza-Romero, Rene Urquidez-Romero, Yan Y. Lam, Jennifer Rood, Leslie O. Schulz, Peter H. Bennett, Mauro E. Valencia, Eric Ravussin Aug 2024

Changes In Energy Expenditure And Physical Activity Over 15 Years Of Environmental Changes: The Maycoba Project, Alexandra Niclou, Julián Esparza-Romero, Rene Urquidez-Romero, Yan Y. Lam, Jennifer Rood, Leslie O. Schulz, Peter H. Bennett, Mauro E. Valencia, Eric Ravussin

Clinical Research Faculty Publications

Objective: This work aimed to parse out the role of changing environments on body composition, total energy expenditure, and physical activity in the Mexican Pima, a population experiencing rapid industrialization. Methods: Using doubly labeled water, we compared energy expenditure and physical activity in a longitudinal cohort of Mexican Pima (n = 26; female: 12) in 1995 and 2010. Body mass and composition were assessed by bioimpedance analysis. To determine the effects of environmental factors on body weight independent of age, we compared the 1995 longitudinal cohort with an age- and sex-matched cross-sectional cohort (n = 26) in 2010. Results: Body …


Computed Tomography And Dual-Energy X-Ray Asorptiometry Body Composition Parameter Harmonisation To Universalise Adipose Tissue Measurements In A Population-Based Cross-Sectional Study, Elliot T. Varney, Seth Lirette, Peter T. Katzmarzyk, Frank Greenway, Candace M. Howard Aug 2024

Computed Tomography And Dual-Energy X-Ray Asorptiometry Body Composition Parameter Harmonisation To Universalise Adipose Tissue Measurements In A Population-Based Cross-Sectional Study, Elliot T. Varney, Seth Lirette, Peter T. Katzmarzyk, Frank Greenway, Candace M. Howard

Population and Public Health Science Faculty Publications

To harmonise computed tomography (CT) and dual-energy x-ray absorptiometry (DXA) body composition measurements allowing easy conversion in longitudinal assessments and across cohorts to assess cardiometabolic risk and disease. Retrospective cross-sectional observational study from 1996 to 2008 included participants in the Pennington Center Longitudinal Study (PCLS) (N = 1967; 571 African American/1396 White). Anthropometrics, whole-body DXA and abdominal CT images were obtained. Multi-layer segmentation techniques (Analyze; Rochester, MN) quantified visceral adipose tissue (VAT). Clinical biomarkers were obtained from routine blood samples. Linear models were used to predict CT-VAT from DXA-VAT and examine the effects of traditional biomarkers on cross-sectional-VAT. Predicted CT-VAT …


Obesity- And Diet-Induced Plasticity In Systems That Control Eating And Energy Balance, Carrie R. Ferrario, Heike Münzberg-Gruening, Linda Rinaman, J. Nicholas Betley, Stephanie L. Borgland, Monica Dus, Debra A. Fadool, Kathryn F. Medler, Gregory J. Morton, Darleen A. Sandoval, Claire B. De La Serre, Sarah A. Stanley, Kristy L. Townsend, Alan G. Watts, Padma Maruvada, Diana Cummings, Bradley M. Cooke Aug 2024

Obesity- And Diet-Induced Plasticity In Systems That Control Eating And Energy Balance, Carrie R. Ferrario, Heike Münzberg-Gruening, Linda Rinaman, J. Nicholas Betley, Stephanie L. Borgland, Monica Dus, Debra A. Fadool, Kathryn F. Medler, Gregory J. Morton, Darleen A. Sandoval, Claire B. De La Serre, Sarah A. Stanley, Kristy L. Townsend, Alan G. Watts, Padma Maruvada, Diana Cummings, Bradley M. Cooke

Division of Basic Science Faculty Publications

In April 2023, the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), in partnership with the National Institute of Child Health and Human Development, the National Institute on Aging, and the Office of Behavioral and Social Sciences Research, hosted a 2-day online workshop to discuss neural plasticity in energy homeostasis and obesity. The goal was to provide a broad view of current knowledge while identifying research questions and challenges regarding neural systems that control food intake and energy balance. This review includes highlights from the meeting and is intended both to introduce unfamiliar audiences with concepts central to …


Effects Of E-Cigarettes On The Lung And Systemic Metabolome In People With Hiv, Aline Zaparte, Courtney J. Christopher, Connie Arnold, Lauren Richey, Adairre Castille, Kyle Mistretta, Christopher M. Taylor, Huiyi Lin, Steve Nelson, John P. Kirwan, John W. Apolzan, Shawn R. Campagna, David A. Welsh Aug 2024

Effects Of E-Cigarettes On The Lung And Systemic Metabolome In People With Hiv, Aline Zaparte, Courtney J. Christopher, Connie Arnold, Lauren Richey, Adairre Castille, Kyle Mistretta, Christopher M. Taylor, Huiyi Lin, Steve Nelson, John P. Kirwan, John W. Apolzan, Shawn R. Campagna, David A. Welsh

Division of Basic Science Faculty Publications

The popularity of e-cigarettes (vaping) has soared, creating a public health crisis among teens and young adults. Chronic vaping can induce gut inflammation and reduce intestinal barrier function through the production of the proinflammatory molecule hydrogen sulfide (H2S). This is particularly concerning for people with HIV (PWH) as they already face impaired immune function and are at a higher risk for metabolic dysregulation, diabetes, and chronic liver disease. Furthermore, PWH experience unhealthy behaviors, making it crucial to understand the systemic metabolic dysregulation and pathophysiological mechanisms associated with vaping in this population. Here, we employed liquid chromatography–mass spectrometry (LC-MS)-based metabolomics to …


The Bioenergetic Landscape Of Cancer, Elizabeth R.M. Zunica, Christopher L. Axelrod, L. Anne Gilmore, Erich Gnaiger, John P. Kirwan Aug 2024

The Bioenergetic Landscape Of Cancer, Elizabeth R.M. Zunica, Christopher L. Axelrod, L. Anne Gilmore, Erich Gnaiger, John P. Kirwan

Division of Basic Science Faculty Publications

Background: Bioenergetic remodeling of core energy metabolism is essential to the initiation, survival, and progression of cancer cells through exergonic supply of adenosine triphosphate (ATP) and metabolic intermediates, as well as control of redox homeostasis. Mitochondria are evolutionarily conserved organelles that mediate cell survival by conferring energetic plasticity and adaptive potential. Mitochondrial ATP synthesis is coupled to the oxidation of a variety of substrates generated through diverse metabolic pathways. As such, inhibition of the mitochondrial bioenergetic system by restricting metabolite availability, direct inhibition of the respiratory Complexes, altering organelle structure, or coupling efficiency may restrict carcinogenic potential and cancer progression. …


Youth's Political Identity And Fertility Desires, Heather M. Rackin, Christina M. Gibson-Davis Aug 2024

Youth's Political Identity And Fertility Desires, Heather M. Rackin, Christina M. Gibson-Davis

Faculty Publications

Objective: This study examines the association between political identity and young adults' fertility desires from 1989 to 2019. Background: Understanding the factors that shape fertility preferences is important because these preferences are the critical bridge between social forces and fertility. Identity is a theorized, but understudied, predictor of fertility desires. The increasing salience of political identity suggests that the association between political identity and fertility desires has strengthened over time. Method: Data come from the 1989–2019 waves of Monitoring the Future, a nationally representative study of 12th graders (N = 67,557). Regression models examined how political identity (measured by Republican …


Discovery Of A Strong Rotation Of The X-Ray Polarization Angle In The Galactic Burster Gx 13+1, Anna Bobrikova, Sofia V. Forsblom, Alessandro Di Marco, Fabio La Monaca, Juri Poutanen, Mason Ng, Swati Ravi, Vladislav Loktev, Jari J.E. Kajava, Francesco Ursini, Alexandra Veledina, Daniele Rogantini, Tuomo Salmi, Stefano Bianchi, Fiamma Capitanio, Chris Done, Sergio Fabiani, Andrea Gnarini, Jeremy Heyl, Philip Kaaret, Giorgio Matt, Fabio Muleri, Anagha P. Nitindala, John Rankin, Martin C. Weisskopf, Iván Agudo, Lucio A. Antonelli, Matteo Bachetti, Luca Baldini, Wayne H. Baumgartner, Ronaldo Bellazzini, Stephen D. Bongiorno, Raffaella Bonino Aug 2024

Discovery Of A Strong Rotation Of The X-Ray Polarization Angle In The Galactic Burster Gx 13+1, Anna Bobrikova, Sofia V. Forsblom, Alessandro Di Marco, Fabio La Monaca, Juri Poutanen, Mason Ng, Swati Ravi, Vladislav Loktev, Jari J.E. Kajava, Francesco Ursini, Alexandra Veledina, Daniele Rogantini, Tuomo Salmi, Stefano Bianchi, Fiamma Capitanio, Chris Done, Sergio Fabiani, Andrea Gnarini, Jeremy Heyl, Philip Kaaret, Giorgio Matt, Fabio Muleri, Anagha P. Nitindala, John Rankin, Martin C. Weisskopf, Iván Agudo, Lucio A. Antonelli, Matteo Bachetti, Luca Baldini, Wayne H. Baumgartner, Ronaldo Bellazzini, Stephen D. Bongiorno, Raffaella Bonino

Faculty Publications

Weakly magnetized neutron stars in X-ray binaries show a complex phenomenology with several spectral components that can be associated with the accretion disk, the boundary, and/or a spreading layer, a corona, and a wind. Spectroscopic information alone, however, is not enough to distinguish these components. The analysis of the timing data revealed that most of the variability, and in particular, kilohertz quasi-period oscillations, are associated with the high-energy component that corresponds to the boundary and/or spreading layer. Additional information about the nature of the spectral components, and in particular, about the geometry of the emission region, can be provided by …


Effects Of Exercise Or Metformin On Myokine Concentrations In Patients With Breast And Colorectal Cancer: A Phase Ii Multi-Centre Factorial Randomized Trial, Justin C. Brown, Guillaume Spielmann, Shengping Yang, Stephanie L.E. Compton, Lee W. Jones, Melinda L. Irwin, Jennifer A. Ligibel, Jeffrey A. Meyerhardt Aug 2024

Effects Of Exercise Or Metformin On Myokine Concentrations In Patients With Breast And Colorectal Cancer: A Phase Ii Multi-Centre Factorial Randomized Trial, Justin C. Brown, Guillaume Spielmann, Shengping Yang, Stephanie L.E. Compton, Lee W. Jones, Melinda L. Irwin, Jennifer A. Ligibel, Jeffrey A. Meyerhardt

Faculty Publications

Background: Physical activity and metformin pharmacotherapy are associated with improved clinical outcomes in breast and colorectal cancer survivors. Myokines are cytokines secreted from skeletal muscle that may mediate these associations. Methods: This hypothesis-generating analysis used biospecimens collected from a multi-centre 2 × 2 factorial randomized design of 116 patients with stage I–III breast and colorectal cancer who were randomized to 12 weeks of (1) aerobic exercise (moderate intensity titrated to 220 min/week); (2) metformin (850 mg daily for 2 weeks and then titrated to 850 mg twice per day); (3) aerobic exercise and metformin; or (4) control. Fourteen myokines were …


Prevalence And Correlates Of Adherence To The Global Total Physical Activity Guideline Based On Step Counting Among 3- To 4-Year-Olds: Evidence From Sunrise Pilot Studies From 17 Countries, Tawonga W. Mwase-Vuma, Xanne Janssen, Kar Hau Chong, Anthony D. Okely, Mark S. Tremblay, Catherine E. Draper, E. Kipling Webster, Alex Antonio Florindo, Amanda E. Staiano, Bang Nguyen Pham, Chiaki Tanaka, Denise Koh, Hongyan Guan, Hong K. Tang, Marie Löf, Mohammad Sorowar Hossain, Nyaradzai E. Munambah, Penny Cross, P. W.Prasad Chathurangana, John J. Reilly Aug 2024

Prevalence And Correlates Of Adherence To The Global Total Physical Activity Guideline Based On Step Counting Among 3- To 4-Year-Olds: Evidence From Sunrise Pilot Studies From 17 Countries, Tawonga W. Mwase-Vuma, Xanne Janssen, Kar Hau Chong, Anthony D. Okely, Mark S. Tremblay, Catherine E. Draper, E. Kipling Webster, Alex Antonio Florindo, Amanda E. Staiano, Bang Nguyen Pham, Chiaki Tanaka, Denise Koh, Hongyan Guan, Hong K. Tang, Marie Löf, Mohammad Sorowar Hossain, Nyaradzai E. Munambah, Penny Cross, P. W.Prasad Chathurangana, John J. Reilly

Population and Public Health Science Faculty Publications

Background: There is limited evidence from globally diverse samples on the prevalence and correlates of meeting the global guideline of 180 minutes per day of total physical activity (TPA) among 3- to 4-year-olds. Methods: Cross-sectional study involving 797 (49.2% girls) 3- to 4-year-olds from 17 middle- and high-income countries who participated in the pilot phases 1 and 2 of the SUNRISE International Study of Movement Behaviours in the Early Years. Daily step count was measured using thigh-worn activPAL accelerometers. Children wore the accelerometers for at least one 24-hour period. Children were categorized as meeting the TPA guideline based on achieving …


Anderson Localization For The Unitary Almost Mathieu Operator, Fan Yang Aug 2024

Anderson Localization For The Unitary Almost Mathieu Operator, Fan Yang

Faculty Publications

We prove Anderson localization for all Diophantine frequencies and all non-resonant phases for a model that arises from a 2D quantum walk model subject to an external magnetic field, also known as the unitary almost Mathieu operator. Our work provides the first localization results for all Diophantine frequencies in quasi-periodic quantum walk and CMV matrix setting. We also obtain sharp asymptotics of the localized eigenfunctions.


Acute Pancreatitis In Individuals With Sickle Cell Disease: A Systematic Review, Chinenye R. Dike, Adefunke Dadematthews, Oluwagbemiga Dadematthews, Maisam Abu-El-Haija, Jeffrey Lebensburger, Abigail Smith, Aamer Imdad Aug 2024

Acute Pancreatitis In Individuals With Sickle Cell Disease: A Systematic Review, Chinenye R. Dike, Adefunke Dadematthews, Oluwagbemiga Dadematthews, Maisam Abu-El-Haija, Jeffrey Lebensburger, Abigail Smith, Aamer Imdad

Faculty Publications

Background/Objectives: Sickle cell disease (SCD) impacts about 100,000 people in the US. SCD increases the risk of cholelithiasis and microvascular ischemia, which could increase the risk of acute pancreatitis (AP). Abdominal pain is a common presenting symptom of AP and sickle cell vaso-occlusive crisis. The purpose of our systematic review is to estimate the prevalence and determine the severity of AP in individuals with SCD compared to the general population. Methods: Multiple electronic databases were searched. We included studies that included children and adults (population) and addressed the association of SCD (exposure) with AP (outcome) compared to the same population …


Effects Of Non-Face-To-Face Chronic Care Management On Service Utilization And Outcomes Among Us Medicare Beneficiaries With Diabetes, Dongzhe Hong, Charles Stoecker, Yixue Shao, Elizabeth Nauman, Vivian Fonseca, Gang Hu, Alessandra N. Bazzano, Edmond K. Kabagambe, Lizheng Shi Aug 2024

Effects Of Non-Face-To-Face Chronic Care Management On Service Utilization And Outcomes Among Us Medicare Beneficiaries With Diabetes, Dongzhe Hong, Charles Stoecker, Yixue Shao, Elizabeth Nauman, Vivian Fonseca, Gang Hu, Alessandra N. Bazzano, Edmond K. Kabagambe, Lizheng Shi

Population and Public Health Science Faculty Publications

Background: Type 2 diabetes mellitus (T2DM) results in heavy economic and disease burdens in Louisiana. The Centers for Medicare and Medicaid Services has reimbursed non-face-to-face chronic care management (NFFCCM) for patients with two or more chronic conditions since 2015. Objective: To assess the impacts of NFFCCM on healthcare utilization and health outcomes. Design, Setting, and Participants: This retrospective cohort study included Medicare fee-for-service beneficiaries with T2DM and at least one additional chronic disease between 2014 and 2018. Exposures: At least one record of NFFCCM Current Procedural Terminology codes. Main Measures: The health outcomes in the study included major adverse cardiovascular …


The Risk Management Of Covid-19: Lessons From Financial Economics And Financial Risk Management, Don M. Chance Aug 2024

The Risk Management Of Covid-19: Lessons From Financial Economics And Financial Risk Management, Don M. Chance

Faculty Publications

The United States had one of the worst outcomes in the management of COVID-19 risk, with a death rate in the 94th percentile of all countries. Setting aside the obvious politicized nature of COVID-19 public health recommendations and mandates, we argue that best practices in financial risk management provide parallels that could have served as valuable guidance. We demonstrate here that considerable signals were missed that would have required very little effort and would have been consistent with sound risk management. We also identify examples of misleading information such as that COVID-19 was particularly hard on the elderly. The data …


Editorial Introduction: Unveiling New Dimensions In Policy Process Theory Research, Geoboo Song, Saba Siddiki, Melissa K. Merry, Davor Mondom, Ben Galloway, Gwen Arnold, Aaron Smith-Walter, Holly L. Peterson, Creed Tumlison, Briana Huett, Heasun Choi, Nataliia Borozdina Aug 2024

Editorial Introduction: Unveiling New Dimensions In Policy Process Theory Research, Geoboo Song, Saba Siddiki, Melissa K. Merry, Davor Mondom, Ben Galloway, Gwen Arnold, Aaron Smith-Walter, Holly L. Peterson, Creed Tumlison, Briana Huett, Heasun Choi, Nataliia Borozdina

Faculty Publications

No abstract provided.