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The Real Cost To Remain Competitive: Byu Confronts Racist Past, Darron Smith, Lori Latrice Martin Jan 2023

The Real Cost To Remain Competitive: Byu Confronts Racist Past, Darron Smith, Lori Latrice Martin

Faculty Publications

College sports is a multi-billion-dollar business, and universities are looking for ways to remain competitive, including recruiting and retaining athletes from historically underrepresented groups to predominantly white institutions (PWI), many of which have a documented history of excluding non-white students, including blacks, indigenous peoples, and other people of color (often referred to as BIPOC). This article will examine the legacy of the racist teachings, past controversies, and compromises of the Church of Jesus Christ of Latter-day Saints (LDS, Mormons) along with persistent struggles to shake off its 130-year-old racist past in efforts for its flagship school, Brigham Young University, to …

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Transcriptome Analysis Of Two Near-Isogenic Lines Of Bell Pepper (Capsicum Annuum) Infected With Bell Pepper Endornavirus And Pepper Mild Mottle Virus, Cesar Escalante, Noa Sela, Rodrigo A. Valverde Jan 2023

Transcriptome Analysis Of Two Near-Isogenic Lines Of Bell Pepper (Capsicum Annuum) Infected With Bell Pepper Endornavirus And Pepper Mild Mottle Virus, Cesar Escalante, Noa Sela, Rodrigo A. Valverde

Faculty Publications

No abstract provided.

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Black:White Health Inequalities, Genes Versus Environment—A New Chapter?, Richard Cooper Jan 2023

Black:White Health Inequalities, Genes Versus Environment—A New Chapter?, Richard Cooper

Faculty Publications

No abstract provided.

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Gene-Educational Attainment Interactions In A Multi-Population Genome-Wide Meta-Analysis Identify Novel Lipid Loci, Lisa De Las Fuentes, Karen L. Schwander, Michael R. Brown, Amy R. Bentley, Thomas W. Winkler, Yun Ju Sung, Patricia B. Munroe, Clint L. Miller, Hugo Aschard, Stella Aslibekyan, Traci M. Bartz, Lawrence F. Bielak, Jin Fang Chai, Ching Yu Cheng, Rajkumar Dorajoo, Mary F. Feitosa, Xiuqing Guo, Fernando P. Hartwig, Andrea Horimoto, Ivana Kolčić, Elise Lim, Yongmei Liu, Alisa K. Manning, Jonathan Marten, Solomon K. Musani, Raymond Noordam, Sandosh Padmanabhan, Tuomo Rankinen, Melissa A. Richard, Paul M. Ridker, Albert V. Smith, Dina Vojinovic, Alan B. Zonderman Jan 2023

Gene-Educational Attainment Interactions In A Multi-Population Genome-Wide Meta-Analysis Identify Novel Lipid Loci, Lisa De Las Fuentes, Karen L. Schwander, Michael R. Brown, Amy R. Bentley, Thomas W. Winkler, Yun Ju Sung, Patricia B. Munroe, Clint L. Miller, Hugo Aschard, Stella Aslibekyan, Traci M. Bartz, Lawrence F. Bielak, Jin Fang Chai, Ching Yu Cheng, Rajkumar Dorajoo, Mary F. Feitosa, Xiuqing Guo, Fernando P. Hartwig, Andrea Horimoto, Ivana Kolčić, Elise Lim, Yongmei Liu, Alisa K. Manning, Jonathan Marten, Solomon K. Musani, Raymond Noordam, Sandosh Padmanabhan, Tuomo Rankinen, Melissa A. Richard, Paul M. Ridker, Albert V. Smith, Dina Vojinovic, Alan B. Zonderman

Faculty Publications

Introduction: Educational attainment, widely used in epidemiologic studies as a surrogate for socioeconomic status, is a predictor of cardiovascular health outcomes. Methods: A two-stage genome-wide meta-analysis of low-density lipoprotein cholesterol (LDL), high-density lipoprotein cholesterol (HDL), and triglyceride (TG) levels was performed while accounting for gene-educational attainment interactions in up to 226,315 individuals from five population groups. We considered two educational attainment variables: “Some College” (yes/no, for any education beyond high school) and “Graduated College” (yes/no, for completing a 4-year college degree). Genome-wide significant (p < 5 × 10−8) and suggestive (p < 1 × 10−6) variants were identified in Stage 1 (in up to 108,784 individuals) through genome-wide analysis, and those variants were followed up in Stage 2 studies (in up to 117,531 individuals). Results: In combined analysis of Stages 1 and 2, we identified 18 novel lipid loci (nine for LDL, seven for HDL, and two for TG) by two degree-of-freedom (2 DF) joint tests of main and interaction effects. Four loci showed significant interaction with educational attainment. Two loci were significant only in cross-population analyses. Several loci include genes with known or suggested roles in adipose (FOXP1, MBOAT4, SKP2, STIM1, STX4), brain (BRI3, FILIP1, FOXP1, LINC00290, LMTK2, MBOAT4, MYO6, SENP6, SRGAP3, STIM1, TMEM167A, TMEM30A), and liver (BRI3, FOXP1) biology, highlighting the potential importance of brain-adipose-liver communication in the regulation of lipid metabolism. An investigation of the potential druggability of genes in identified loci resulted in five gene targets shown to interact with drugs approved by the Food and Drug Administration, including genes with roles in adipose and brain tissue. Discussion: Genome-wide interaction analysis of educational attainment identified novel lipid loci not previously detected by analyses limited to main genetic effects.

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Biochemical Alterations In The Follicular Fluid Of Bovine Peri-Ovulatory Follicles And Their Association With Final Oocyte Maturation, Noof Abdulrahman Alrabiah, Constantine A. Simintiras, Alexander C.O. Evans, Patrick Lonergan, Trudee Fair Jan 2023

Biochemical Alterations In The Follicular Fluid Of Bovine Peri-Ovulatory Follicles And Their Association With Final Oocyte Maturation, Noof Abdulrahman Alrabiah, Constantine A. Simintiras, Alexander C.O. Evans, Patrick Lonergan, Trudee Fair

Faculty Publications

Follicular fluid (FF), a product of vascular transudate and granulosa and thecal cell secretions, is the milieu that has evolved to support oocyte growth and maturation which plays a central role in oocyte quality determination. Therefore, a suboptimal FF composition may be reflected in compromised oocyte progression through maturation, fertilization, or embryo development. To date, the composition of bovine FF remains understudied. To address this, we comprehensively characterized the metabolomic constituency of bovine FF in the period during which the oocyte undergoes meiotic maturation. More specifically, FF from pre (-24 h) and peri (-2 h)-ovulatory follicles was profiled by high-throughput …

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Evidence For The Efficacy Of Pre-Harvest Agricultural Practices In Mitigating Food-Safety Risks To Fresh Produce In North America, Naresh Devarajan, Daniel L. Weller, Matthew Jones, Aiko D. Adell, Achyut Adhikari, Ana Allende, Nicole L. Arnold, Patrick Baur, Sarah M. Beno, Donna Clements, Elissa M. Olimpi, Faith Critzer, Hyatt Green, Lisa Gorski, Angela Ferelli Gruber, Jasna Kovac, Jeffery Mcgarvey, Claire M. Murphy, Sarah I. Murphy, Nora Navarro-Gonzalez, Jeb P. Owen, Alda F.A. Pires, Nicole Richard, Sandipan Samaddar, Radomir Schmidt, Kate Scow, Nikki W. Shariat, Olivia M. Smith, Austin R. Spence, Don Stoeckel, Thao D.H. Tran, Gretchen Wall, Daniel S. Karp Jan 2023

Evidence For The Efficacy Of Pre-Harvest Agricultural Practices In Mitigating Food-Safety Risks To Fresh Produce In North America, Naresh Devarajan, Daniel L. Weller, Matthew Jones, Aiko D. Adell, Achyut Adhikari, Ana Allende, Nicole L. Arnold, Patrick Baur, Sarah M. Beno, Donna Clements, Elissa M. Olimpi, Faith Critzer, Hyatt Green, Lisa Gorski, Angela Ferelli Gruber, Jasna Kovac, Jeffery Mcgarvey, Claire M. Murphy, Sarah I. Murphy, Nora Navarro-Gonzalez, Jeb P. Owen, Alda F.A. Pires, Nicole Richard, Sandipan Samaddar, Radomir Schmidt, Kate Scow, Nikki W. Shariat, Olivia M. Smith, Austin R. Spence, Don Stoeckel, Thao D.H. Tran, Gretchen Wall, Daniel S. Karp

Faculty Publications

Consumption of contaminated produce remains a leading cause of foodborne illness. Increasingly, growers are altering agricultural practices and farm environments to manage food-safety hazards, but these changes often result in substantial economic, social, and environmental costs. Here, we present a comprehensive evidence synthesis evaluating the efficacy of soil, non-crop vegetation, animal, landscape, and irrigation water management strategies aimed at reducing produce-safety risk in North America. We systematically summarized findings from 78 peer-reviewed papers on the effect of 21 management practices on the prevalence, abundance, or survival of four foodborne pathogens (i.e., E. coli, Salmonella spp., Listeria spp., and Campylobacter spp.), …

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Comprehensive Meta-Analysis Of Qtl And Gene Expression Studies Identify Candidate Genes Associated With Aspergillus Flavus Resistance In Maize, Niranjan Baisakh, Eduardo A. Da Silva, Anjan K. Pradhan, Kanniah Rajasekaran Jan 2023

Comprehensive Meta-Analysis Of Qtl And Gene Expression Studies Identify Candidate Genes Associated With Aspergillus Flavus Resistance In Maize, Niranjan Baisakh, Eduardo A. Da Silva, Anjan K. Pradhan, Kanniah Rajasekaran

Faculty Publications

Aflatoxin (AF) contamination, caused by Aspergillus flavus, compromises the food safety and marketability of commodities, such as maize, cotton, peanuts, and tree nuts. Multigenic inheritance of AF resistance impedes conventional introgression of resistance traits into high-yielding commercial maize varieties. Several AF resistance-associated quantitative trait loci (QTLs) and markers have been reported from multiple biparental mapping and genome-wide association studies (GWAS) in maize. However, QTLs with large confidence intervals (CI) explaining inconsistent phenotypic variance limit their use in marker-assisted selection. Meta-analysis of published QTLs can identify significant meta-QTLs (MQTLs) with a narrower CI for reliable identification of genes and linked markers …

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The Inheritance Of Energy And The Evolution Of Unsustainability, Brian Snyder Jan 2023

The Inheritance Of Energy And The Evolution Of Unsustainability, Brian Snyder

Faculty Publications

Across contemporary and historical human groups, there is variation in how cultures interact with the environment and this variation is inherited through culture. Some human-environment relationships maximize group fitness relative to other relationships. Thus, there is heritable, fitness-associated variation in human-environment interactions and so human-environment interactions may be understood to be an evolved trait. However, one fitness-maximizing human-environment relationship could be unsustainable resource extraction. Anthroecological theory proposes that human cultures and genotypes have been selected for unsustainability, although several mechanisms have been proposed for how this selection may have worked. Here, I extend anthroecological theory and argue that energy inheritances …

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Going With The Flow: The Supply And Demand Of Sediment Retention Ecosystem Services For The Reservoirs In Puerto Rico, R. De Jesus Crespo, M. Valladares-Castellanos, Volodymyr V. Mihunov, T. H. Douthat Jan 2023

Going With The Flow: The Supply And Demand Of Sediment Retention Ecosystem Services For The Reservoirs In Puerto Rico, R. De Jesus Crespo, M. Valladares-Castellanos, Volodymyr V. Mihunov, T. H. Douthat

Faculty Publications

Impounding surface waters in reservoirs is a major mechanism for providing water for human consumption, including potable water, hydroelectric power, and industrial uses. Building reservoirs incurs environmental and social costs, and therefore safeguarding their effectiveness and longevity is a concern of clear public interest. One factor that affects the longevity of reservoirs is sedimentation, a process exacerbated by land use conversion in upstream watershed areas. Despite the economic importance of preventing sedimentation in existing reservoirs, few consumers are aware of the natural features that provide sediment retention services and the relevance of their conservation in their daily lives. Moreover, managing …

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Charting The Course To Advance Dei In The Ocean Sciences A Case Study, Christopher F. D’Elia, Katherine Falls, Sibel Bargu, Linda Hooper-Bùi Jan 2023

Charting The Course To Advance Dei In The Ocean Sciences A Case Study, Christopher F. D’Elia, Katherine Falls, Sibel Bargu, Linda Hooper-Bùi

Faculty Publications

The Louisiana State University College of the Coast & Environment (LSU CC&E) developed a multi-faceted strategic initiative to increase its diversity, equity, and inclusion. Elements of this initiative began one-by-one over the last decade and were aggregated into a comprehensive implementation plan—the 2020 CC&E Diversity, Equity, and Inclusion Action Plan. Based on best practices in the “physical sciences” (i.e., geosciences, including oceanography), the plan aims to augment recruitment and retention using limited resources and personnel. The long-range goal is to increase the number of PhD graduates from underrepresented groups by employing strategies that start at the 6–12th grade level. The …

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Understanding The Developments In The Business Perspective Of Cloud Computing: A Multidimensional Scaling Analysis, Harsh Parekh, Huai Tzu Cheng, Andrew Schwarz Jan 2023

Understanding The Developments In The Business Perspective Of Cloud Computing: A Multidimensional Scaling Analysis, Harsh Parekh, Huai Tzu Cheng, Andrew Schwarz

Faculty Publications

Research on cloud computing (CC) has gained a lot of momentum owing to its massive adoption. It has moved beyond the exploration of inherent capabilities to understand its disruptiveness and transformative value. In this vein, the authors conducted a comparative literature review of 101 articles to better understand the developments from previous reviews. This article serves as a replication study to evaluate the growth of the business perspective of CC. The authors identify 126 factors guiding the characteristics, adoption, governance, and business impact of the cloud. Further, they employ a rigorous analysis that situates our review at the intersection of …

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Quasistatic Evolution With Unstable Forces, Debdeep Bhattacharya, Robert P. Lipton Jan 2023

Quasistatic Evolution With Unstable Forces, Debdeep Bhattacharya, Robert P. Lipton

Faculty Publications

We consider load controlled quasistatic evolution. Well posedness results for the nonlocal continuum model related to peridynamics are established. We show local existence and uniqueness of quasistatic evolution for load paths originating at stable critical points. These points can be associated with local energy minima among the convex set of deformations belonging to the strength domain of the material. The evolution of the displacements, however, is not constrained to lie inside the strength domain of the material. The load-controlled evolution is shown to exhibit energy balance.

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Simulating Grain Shape Effects And Damage In Granular Media Using Peridem, Debdeep Bhattacharya, Robert P. Lipton Jan 2023

Simulating Grain Shape Effects And Damage In Granular Media Using Peridem, Debdeep Bhattacharya, Robert P. Lipton

Faculty Publications

We provide a numerical platform for the analysis of particle shape and topology effect on the macroscopic behavior of granular media. We work within a discrete element method (DEM) framework and apply a peridynamic model for deformable particles accounting for deformation and damage of individual particles. To accommodate arbitrary particle shapes including nonconvex ones as well as particle topology, an efficient method is developed to keep intraparticle peridynamic interaction within particle boundaries. Particle contact with the rigid boundary wall is computed analytically to improve accuracy. To speed up simulations with particles of different shapes and sizes the initial configuration is …

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Discrete-Time Trajectory-Based Stabilization Approach Using Interval Observer, Frederic Mazenc, Michael Malisoff, Jackson Knox Jan 2023

Discrete-Time Trajectory-Based Stabilization Approach Using Interval Observer, Frederic Mazenc, Michael Malisoff, Jackson Knox

Faculty Publications

We provide a discrete-time vector valued analog of recently developed continuous-time trajectory-based estimates. We use it to provide a discrete-time version of Halanay's inequality. We combine the results with interval observers to prove exponential stability properties for discrete-time linear systems with uncertainties whose arbitrarily long input delays are compensated for by reduction model controls, and a robust global exponential stability result for observers for discrete-time linear systems.

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Almost Fixed Time Observers For Parameters And For State Variables Of Nonlinear Systems, Frederic Mazenc, Michael Malisoff, Laurent Burlion Jan 2023

Almost Fixed Time Observers For Parameters And For State Variables Of Nonlinear Systems, Frederic Mazenc, Michael Malisoff, Laurent Burlion

Faculty Publications

We provide new finite-time and fast-converging observers for continuous-time nonlinear systems that contain unknown constant parameters and measurement delays. When the dynamics are affine in the unmeasured state, we obtain fixed time observers that identify unknown states and unknown model parameters. When the dynamics contain a nonlinearity that depends on the unmeasured state, we instead obtain asymptotic convergence of our observers, whose rate of convergence converges to infinity as the growth rate of this nonlinearity converges to zero, so in this case we call the observers almost fixed time observers. Our examples illustrate how our assumptions can be easily checked.

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Mathematical Models Of Topologically Protected Transport In Twisted Bilayer Graphene, Guillaume Bal, Paul Cazeaux, Daniel Massatt, Solomon Quinn Jan 2023

Mathematical Models Of Topologically Protected Transport In Twisted Bilayer Graphene, Guillaume Bal, Paul Cazeaux, Daniel Massatt, Solomon Quinn

Faculty Publications

Twisted bilayer graphene gives rise to large moir\'e patterns that form a triangular network upon mechanical relaxation. If gating is included, each triangular region has gapped electronic Dirac points that behave as bulk topological insulators with topological indices depending on valley index and the type of stacking. Since each triangle has two oppositely charged valleys, they remain topologically trivial. In this work, we address several questions related to the edge currents of this system by analysis and computation of continuum PDE models. First, we derive the bulk invariants corresponding to a single valley, and then apply a bulk-interface correspondence to …

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Seepage-Induced Pore Pressure Variations Beneath An Earthen Levee Measured With A Novel Seismic Tool, Daniel Locci-Lopez, Juan M. Lorenzo Jan 2023

Seepage-Induced Pore Pressure Variations Beneath An Earthen Levee Measured With A Novel Seismic Tool, Daniel Locci-Lopez, Juan M. Lorenzo

Faculty Publications

Shear-wave seismic reflection velocity-versus-depth models can complement our understanding of seepage pore pressure variations beneath earthen levees at locations between geotechnical sites. The seasonal variations of water level in the Mississippi River create pore pressure changes in the adjacent hydraulically connected aquifer on the protected side of artificial levees. Time-lapse shear-wave velocity analysis or repetition of seismic acquisition over an area is a non-invasive method that can detect seasonal pore pressure variations in shallow (< 40 m) aquifers. The seismic reflection patterns during the seasonal pore pressure variations of the river show a distinctive change in the velocity semblance analysis, which is translated as a change in the average stress carried by the grain-to-grain contact, or simply the effective pressure. The seismic data show a greater variation of up to +140/−40 m/s or +700/−150 kPa in the confined aquifer zone, compared with the leaky confined aquifer zone of up to +46/−48 m/s or +140/−80 kPa. These relative effective pressure characteristics allow us to distinguish between confined and leaky aquifers and can be an optional approach for pressure prediction in floodplains along levees without the need to drill borings in the area to measure piezometric data.

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The Lagrangian Numerical Relativity Code Sphincs_Bssn_V1.0, Stephan Rosswog, Francesco Torsello, Peter Diener Jan 2023

The Lagrangian Numerical Relativity Code Sphincs_Bssn_V1.0, Stephan Rosswog, Francesco Torsello, Peter Diener

Faculty Publications

We present version 1.0 of our Lagrangian numerical relativity code SPHINCS_BSSN. This code evolves the full set of Einstein equations, but contrary to other numerical relativity codes, it evolves the matter fluid via Lagrangian particles in the framework of a high-accuracy version of smooth particle hydrodynamics (SPH). The major new elements introduced here are: (i) a new method to map the stress–energy tensor (known at the particles) to the spacetime mesh, based on a local regression estimate; (ii) additional measures that ensure the robust evolution of a neutron star through its collapse to a black hole; and (iii) further refinements …

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Lsu General Catalog 2023-2024, Louisiana State University And Agricultural And Mechanical College Jan 2023

Lsu General Catalog 2023-2024, Louisiana State University And Agricultural And Mechanical College

LSU General Catalog

The LSU General Catalog describes all undergraduate and graduate departments and programs with degree requirements and courses offered for each one. The LSU General Catalog includes information on registration and financial aid as well as academic services offered to all students.

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Ab Initio Symmetry-Adapted Emulator For Studying Emergent Collectivity And Clustering In Nuclei, K. S. Becker, K. D. Launey, A. Ekström, T. Dytrych Jan 2023

Ab Initio Symmetry-Adapted Emulator For Studying Emergent Collectivity And Clustering In Nuclei, K. S. Becker, K. D. Launey, A. Ekström, T. Dytrych

Faculty Publications

We discuss emulators from the ab initio symmetry-adapted no-core shell-model framework for studying the formation of alpha clustering and collective properties without effective charges. We present a new type of an emulator, one that utilizes the eigenvector continuation technique but is based on the use of symplectic symmetry considerations. This is achieved by using physically relevant degrees of freedom, namely, the symmetry-adapted basis, which exploits the almost perfect symplectic symmetry in nuclei. Specifically, we study excitation energies, point-proton root-mean-square radii, along with electric quadrupole moments and transitions for 6Li and 12C. We show that the set of parameterizations …

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Effects Of Anisotropy And Disorder On The Superconducting Properties Of Niobium, Mehdi Zarea, Hikaru Ueki, J. A. Sauls Jan 2023

Effects Of Anisotropy And Disorder On The Superconducting Properties Of Niobium, Mehdi Zarea, Hikaru Ueki, J. A. Sauls

Faculty Publications

We report results for the superconducting transition temperature and anisotropic energy gap for pure niobium based on Eliashberg’s equations and electron and phonon band structures computed from density functional theory. The electronic band structure is used to construct the Fermi surface and calculate the Fermi velocity at each point on the Fermi surface. The phonon bands are in excellent agreement with inelastic neutron scattering data. The corresponding phonon density of states and electron–phonon coupling define the electron–phonon spectral function, α2F(p, p′; ω), and the corresponding electron–phonon pairing interaction, which is the basis for computing the superconducting properties. The …

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Non-Fermi Liquid Behavior In The Three-Dimensional Hubbard Model, Samuel Kellar, Ka Ming Tam, Juana Moreno Jan 2023

Non-Fermi Liquid Behavior In The Three-Dimensional Hubbard Model, Samuel Kellar, Ka Ming Tam, Juana Moreno

Faculty Publications

We present a numerical study on the non-Fermi liquid behavior of a three-dimensional strongly correlated system. The Hubbard model in a simple cubic lattice is simulated by the dynamical cluster approximation; in particular, the quasi-particle weight is calculated at finite dopings for a range of temperatures. By fitting the quasi-particle weight to the marginal Fermi liquid form at finite doping near the putative quantum critical point, we find evidence of a separatrix between Fermi liquid and non-Fermi liquid regions. Our results suggest that a marginal Fermi liquid and possibly a quantum critical point exist in the non-symmetry broken solution of …

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The Link Between Marine Thermal Discharges And Nemopilema Nomurai Blooms Around Nuclear Power Plants, Jiawei Wu, Jie Kong, Edward A. Laws, Xin Liu, Changyun Wang, Jixin Chen, Mianrun Chen, Qingzhen Yao, Yantao Wang, Yu Zhen, Chaolun Li, Bangqin Huang Jan 2023

The Link Between Marine Thermal Discharges And Nemopilema Nomurai Blooms Around Nuclear Power Plants, Jiawei Wu, Jie Kong, Edward A. Laws, Xin Liu, Changyun Wang, Jixin Chen, Mianrun Chen, Qingzhen Yao, Yantao Wang, Yu Zhen, Chaolun Li, Bangqin Huang

Faculty Publications

Recent research has shown that jellyfish blooms occur more frequently near nuclear power plants (NPPs), and a relationship between thermal discharges from the NPPs and the blooms has been hypothesized. There is, however, no direct evidence that links the thermal discharges with jellyfish blooms. In this study, we conducted 3 cruises (pre-bloom, bloom, and post-bloom) during July to September 2017 in the area surrounding the largest NPP in northern China. The water temperature near the cooling water outfall rose by 2 °C. Although we found no significant impact on phytoplankton abundance or community composition near the outfall, a broader analysis …

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The Dose-Response Effect Of Aerobic Exercise On Inflammation In Colon Cancer Survivors, Justin C. Brown, Stephanie L.E. Compton, Jeffrey A. Meyerhardt, Guillaume Spielmann, Shengping Yang Jan 2023

The Dose-Response Effect Of Aerobic Exercise On Inflammation In Colon Cancer Survivors, Justin C. Brown, Stephanie L.E. Compton, Jeffrey A. Meyerhardt, Guillaume Spielmann, Shengping Yang

Faculty Publications

Background: Physical activity after surgical resection for colon cancer is associated with significantly longer disease-free survival. Inflammation is hypothesized to mediate the association between physical activity and disease-free survival in colon cancer. Methods: In this exploratory analysis of a randomized dose-response trial, 39 colon cancer survivors who completed standard therapy were stratified by cancer stage and randomized in a 1:1:1 ratio to one of three treatment groups for 24 weeks of usual-care control, 150 min/wk of moderate-intensity aerobic exercise (low-dose), or 300 min/wk of moderate-intensity aerobic exercise (high-dose). Inflammation outcomes included high-sensitivity C-reactive protein (hs-CRP), interleukin-6 (IL6), and soluble tumor …

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Acute Exercise Induces Distinct Quantitative And Phenotypical T Cell Profiles In Men With Prostate Cancer, Erik D. Hanson, Samy Sakkal, Lauren C. Bates-Fraser, Shadney Que, Eunhan Cho, Guillaume Spielmann, Elif Kadife, John A. Violet, Claudio L. Battaglini, Lee Stoner, David B. Bartlett, Glenn K. Mcconell, Alan Hayes Jan 2023

Acute Exercise Induces Distinct Quantitative And Phenotypical T Cell Profiles In Men With Prostate Cancer, Erik D. Hanson, Samy Sakkal, Lauren C. Bates-Fraser, Shadney Que, Eunhan Cho, Guillaume Spielmann, Elif Kadife, John A. Violet, Claudio L. Battaglini, Lee Stoner, David B. Bartlett, Glenn K. Mcconell, Alan Hayes

Faculty Publications

Background: Reduced testosterone levels can influence immune system function, particularly T cells. Exercise during cancer reduces treatment-related side effects and provide a stimulus to mobilize and redistribute immune cells. However, it is unclear how conventional and unconventional T cells (UTC) respond to acute exercise in prostate cancer survivors compared to healthy controls. Methods: Age-matched prostate cancer survivors on androgen deprivation therapy (ADT) and those without ADT (PCa) along with non-cancer controls (CON) completed ∼45 min of intermittent cycling with 3 min at 60% of peak power interspersed by 1.5 min of rest. Fresh, unstimulated immune cell populations and intracellular perforin …

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Parental Engagement And Implementation Fidelity In A Mhealth Motor Skills Intervention For Young Children, Amanda E. Staiano, Sanjoy Saha, Robbie A. Beyl, Chelsea L. Kracht, Robert L. Newton, E. Kipling Webster Jan 2023

Parental Engagement And Implementation Fidelity In A Mhealth Motor Skills Intervention For Young Children, Amanda E. Staiano, Sanjoy Saha, Robbie A. Beyl, Chelsea L. Kracht, Robert L. Newton, E. Kipling Webster

Population and Public Health Science Faculty Publications

Introduction: Mobile apps (i.e. mHealth) provide unprecedented opportunity for widespread dissemination of health behavior programs. However, for programs directed towards young children, parental engagement may explain differing results of mHealth programs. Within the context of an app-based fundamental motor skill (FMS) intervention that improved children’s motor skills (PLAY), this paper examines parents’ fidelity to the intervention and the extent to which fidelity was related to children’s motor skill improvements. Methods: In the PLAY trial, 72 children aged 3–5 years were randomized for their parents to access a Motor Skills app or Free Play app for a 12-week intervention. The Motor …

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Validation Of Remote Assessment Of Preschool Children's Anthropometrics And Motor Skills, Alyssa M. Button, E. Kipling Webster, Chelsea L. Kracht, Chelsea Hendrick, Anthony Okely, Kar Hau Chong, Penny Cross, Amanda E. Staiano Jan 2023

Validation Of Remote Assessment Of Preschool Children's Anthropometrics And Motor Skills, Alyssa M. Button, E. Kipling Webster, Chelsea L. Kracht, Chelsea Hendrick, Anthony Okely, Kar Hau Chong, Penny Cross, Amanda E. Staiano

Population and Public Health Science Faculty Publications

Introduction: Remotely delivered treatment and research procedures were rapidly adopted in response to the COVID-19 pandemic. However, it is unclear if these measures are valid. The purpose of this study was to compare the validity of anthropometry and motor skill proficiency measurements collected in a remote-setting to in-person setting among a sample of children ages 3–4 years. Methods: Child anthropometry and motor skill performance were measured in-person by trained assessors and by parents at home with remote supervision via videoconference by trained assessors. The following measures from the National Institutes of Health Toolbox were collected: anthropometry (height and weight), manual …

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A Finite Element Method For A Two-Dimensional Pucci Equation, Susanne C. Brenner, Li Yeng Sung, Zhiyu Tan Jan 2023

A Finite Element Method For A Two-Dimensional Pucci Equation, Susanne C. Brenner, Li Yeng Sung, Zhiyu Tan

Faculty Publications

A nonlinear least-squares finite element method for strong solutions of the Dirichlet boundary value problem of a two-dimensional Pucci equation on convex polygonal domains is investigated in this paper. We obtain a priori and a posteriori error estimates and present corroborating numerical results, where the discrete nonsmooth and nonlinear optimization problems are solved by an active set method and an alternating direction method with multipliers.

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Unavoidable Induced Subgraphs Of Large 2-Connected Graphs, Sarah Allred, Guoli Ding, Bogdan Oporowski Jan 2023

Unavoidable Induced Subgraphs Of Large 2-Connected Graphs, Sarah Allred, Guoli Ding, Bogdan Oporowski

Faculty Publications

Ramsey_ proved that for every positive integer n, every sufficiently large graph contains an induced Kn or Kn. Among the many extensions of Ramsey's theorem, there is an analogue for connected graphs: For every positive integer n, every sufficiently large connected graph contains an induced Kn, K1,n, or Pn. In this paper, we establish an analogue for 2-connected graphs. In particular, we prove that for every integer exceeding two, every sufficiently large 2-connected graph contains one of the following as an induced subgraph: Kn, a subdivision of K2,n, a subdivision of K2,n with an edge between the two vertices of …

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On Gupta's Codensity Conjecture, Yan Cao, Guantao Chen, Guoli Ding, Guangming Jing, Wenan Zang Jan 2023

On Gupta's Codensity Conjecture, Yan Cao, Guantao Chen, Guoli Ding, Guangming Jing, Wenan Zang

Faculty Publications

Let G = (V, E) be a multigraph. The cover index ξ (G) of G is the greatest integer k for which there is a coloring of E with k colors such that each vertex of G is incident with at least one edge of each color. Let δ (G) be the minimum degree of G, and let Φ (G) be the codensity of G, defined by Φ (G) = min (equation presented) {2|E+(U)||U|+1 : U ⊆ V, | U| ≥ 3 and odd }, where E+(U) is the set of all edges of G with …

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