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Effects Of Alkylation On Potency Of Benz[A]Anthracene For Ahr2 Transactivation In Nine Species Of Freshwater Fish, Justin Dubiel, Hunter Johnson, Andreas N.M. Eriksson, A. Hontela, Jon A. Doering, Steve Wiseman Jul 2023

Effects Of Alkylation On Potency Of Benz[A]Anthracene For Ahr2 Transactivation In Nine Species Of Freshwater Fish, Justin Dubiel, Hunter Johnson, Andreas N.M. Eriksson, A. Hontela, Jon A. Doering, Steve Wiseman

Faculty Publications

Polycyclic aromatic hydrocarbons (PAHs) are naturally occurring or anthropogenic organic chemicals that can activate the aryl hydrocarbon receptor 2 (AhR2) and induce toxicity in fishes. Alkyl PAHs are more abundant than nonalkylated PAHs in certain environmental matrices and there is growing evidence that alkylation can increase potency, dependent on the position of alkylation. However, it is unknown if the effect of alkylation on potency is conserved across species. In addition, relatively little is known regarding the extent of interspecies variation in sensitivity to PAHs and alkyl PAHs. Therefore, objectives of the present study were to characterize potency of benz[a]anthracene (BAA) …


Simulation Of Radioactive Plume Transport In The Atmosphere Including Dynamics Of Particle Aggregation And Breakup, Alexander I. Wiechert, Austin P. Ladshaw, Yong Ha Kim, Costas Tsouris, Sotira Yiacoumi Jul 2023

Simulation Of Radioactive Plume Transport In The Atmosphere Including Dynamics Of Particle Aggregation And Breakup, Alexander I. Wiechert, Austin P. Ladshaw, Yong Ha Kim, Costas Tsouris, Sotira Yiacoumi

Faculty Publications

Accurate prediction of the atmospheric transport of debris particles relies heavily on our knowledge of the size distribution of the particles within a debris cloud. Assuming a fixed particle size during simulations is not always viable since the size distribution of the debris can change during transport. Various microphysical processes, such as aggregation and breakup, influence debris particles and dictate any changes to the size distribution. To track those changes that can occur, a population balance model can be adopted and instituted within a model framework. Nonetheless, many of the models that simulate the transport of radioactive debris following a …


Reducing The Generation Time In Winter Wheat Cultivars Using Speed Breeding, Adam Schoen, Sydney Wallace, Meghan Fisher Holbert, Gina Brown-Guidera, Stephen Harrison, Paul Murphy, Nicholas Sanantonio, David Van Sanford, Richard Boyles, Mohamed Mergoum, Nidhi Rawat, Vijay Tiwari Jul 2023

Reducing The Generation Time In Winter Wheat Cultivars Using Speed Breeding, Adam Schoen, Sydney Wallace, Meghan Fisher Holbert, Gina Brown-Guidera, Stephen Harrison, Paul Murphy, Nicholas Sanantonio, David Van Sanford, Richard Boyles, Mohamed Mergoum, Nidhi Rawat, Vijay Tiwari

Faculty Publications

Reducing generation time is critical to achieving the goals of genetic gain in important crops like wheat (Triticum aestivum). Speed breeding (SB) has been shown to considerably reduce generation times in crop plants. Unlike spring wheat cultivars, winter wheat varieties require typically 6–9 weeks of cold treatment, called vernalization, for flowering which extends the generation time for the development of improved winter wheat cultivars. Here, we optimized the SB method using a set of 48 diverse soft red winter wheat (SRWW) cultivars by testing vernalization duration, light and temperature requirements, and the viability of seeds harvested after different durations post-anthesis …


Refining 2svca Method For Measuring Telehealth Accessibility Of Primary Care Physicians In Baton Rouge, Louisiana, Lingbo Liu, Jennifer Alford-Teaster, Tracy Onega, Fahui Wang Jul 2023

Refining 2svca Method For Measuring Telehealth Accessibility Of Primary Care Physicians In Baton Rouge, Louisiana, Lingbo Liu, Jennifer Alford-Teaster, Tracy Onega, Fahui Wang

Faculty Publications

Equity in health care delivery is a longstanding concern of public health policy. Telehealth is considered an important way to level the playing field by broadening health services access and improving quality of care and health outcomes. This study refines the recently developed “2-Step Virtual Catchment Area (2SVCA) method” to assess the telehealth accessibility of primary care in the Baton Rouge Metropolitan Statistical Area, Louisiana. The result is compared to that of spatial accessibility via physical visits to care providers based on the popular 2-Step Floating Catchment Area (2SFCA) method. The study shows that both spatial and telehealth accessibilities decline …


Developing Sustainable Asphalt Mixtures Using High-Density Polyethylene Plastic Waste Material, Ibrahim Elnaml, Jun Liu, Louay N. Mohammad, Nazimuddin Wasiuddin, Samuel B. Cooper, Samuel B. Cooper Jul 2023

Developing Sustainable Asphalt Mixtures Using High-Density Polyethylene Plastic Waste Material, Ibrahim Elnaml, Jun Liu, Louay N. Mohammad, Nazimuddin Wasiuddin, Samuel B. Cooper, Samuel B. Cooper

Faculty Publications

There is growing interest in sustainable road pavement technologies to protect the environment and provide economic benefits. Post-consumer recycled (PCR) plastics are considered for construction to address the threat of plastic waste materials (PWM) and to improve sustainability. Asphalt pavement construction is highly considered for PWM recycling due to its large daily production. The purpose of this study is to investigate the performance of asphalt mixture containing PWM, specifically high-density polyethylene (HDPE), and compare its performance with two conventional mixtures. Three asphalt mixtures were considered: (1) mixture with asphalt binder PG 76-22 (SBS-modified); (2) mixture with asphalt binder PG 70-22 …


Measuring Resilience To Sea-Level Rise For Critical Infrastructure Systems: Leveraging Leading Indicators, Lamis Amer, Murat Erkoc, Rusty A. Feagin, Sabarethinam Kameshwar, Katharine J. Mach, Diana Mitsova Jul 2023

Measuring Resilience To Sea-Level Rise For Critical Infrastructure Systems: Leveraging Leading Indicators, Lamis Amer, Murat Erkoc, Rusty A. Feagin, Sabarethinam Kameshwar, Katharine J. Mach, Diana Mitsova

Faculty Publications

There has been a growing interest in research on how to define and build indicators of resilience to address challenges associated with sea-level rise. Most of the proposed methods rely on lagging indicators constructed based on the historical performance of an infrastructure sub-system. These indicators are traditionally utilized to build curves that describe the past response of the sub-system to stressors; these curves are then used to predict the future resilience of the sub-system to hypothesized events. However, there is now a growing concern that this approach cannot provide the best insights for adaptive decision-making across the broader context of …


Flammability Properties Of The Pyrolysis Gas Generated From Willow Wood, Maria Mitu, Domnina Razus, Dorin Boldor, Cosmin Marculescu Jul 2023

Flammability Properties Of The Pyrolysis Gas Generated From Willow Wood, Maria Mitu, Domnina Razus, Dorin Boldor, Cosmin Marculescu

Faculty Publications

Willow wood presents a real interest for biomass pyrolysis due to its fast growth, renewability, and high energy density. Following the pyrolysis of willow wood in an inert atmosphere, a multi-fuel gaseous mixture was obtained, with the following composition (by volume): 38.20% CO/21.87% H2/17.44% CH4/1.15% O2/17.15% CO2/4.19% N2. The propagation of laminar premixed flames in these multifuel mixtures with air was investigated numerically for initial temperatures from 298 to 500 K, initial pressures from 1 to 20 bar, and fuel equivalence ratios between 0.60 and 2.00. The combustion of these gaseous mixtures as free laminar premixed flames was simulated by …


Communicating Nature-Society Relationships In Coastal Louisiana: An Evaluation Of The Ecosystem Services Framework, Vanessa Van Heerden Jun 2023

Communicating Nature-Society Relationships In Coastal Louisiana: An Evaluation Of The Ecosystem Services Framework, Vanessa Van Heerden

LSU Doctoral Dissertations

The ecosystem services (ES) framework is a tool to communicate the value of natural environments to human well-being by monetizing services that natural environments provide to humans. The Louisiana Coastal Master Plan uses the ecosystem services provided by the Mississippi River Delta as rationale for why coastal Louisiana should be protected. Here, I am interested in determining how the ecosystem services framework is used to communicate nature-society relationships in coastal Louisiana. I conducted a meta-analysis and spatial analysis to understand the spatial relationships of ecosystem services in the wetlands of coastal Louisiana. I then conducted a survey of residents of …


Characteristics Of Yogurt And Culture Bacteria As Affected By Ingredients That Help Treat Leaky Gut, Ricardo Jose Santos Aleman Jun 2023

Characteristics Of Yogurt And Culture Bacteria As Affected By Ingredients That Help Treat Leaky Gut, Ricardo Jose Santos Aleman

LSU Doctoral Dissertations

At least 100 million people have leaky gut syndrome. This syndrome is associated with multiple health problems such as diabetes, celiac disease, asthma, multiple sclerosis, and inflammatory bowel disease, costing more than $3 billion per year to treat. L-Glutamine, quercetin, slippery elm bark, marshmallow root, N-acetyl-d-glucosamine (NAG), licorice root, maitake mushrooms, and zinc orotate have been reported to help treat leaky gut.

The objectives were to explore the characteristics of yogurt and culture bacteria as affected by ingredients that help treat leaky gut. In yogurt, the pH, titratable acidity, syneresis, viscosity, color, Streptococcus thermophilus, Lactobacillus bulgaricus, yeast and mold and …


Toward One Health: A Spatial Indicator System To Model The Facilitation Of The Spread Of Zoonotic Diseases, Daniel Jato-Espino, Fernando Mayor-Vitoria, Vanessa Moscardó, Fabio Capra-Ribeiro, Leticia Bartolome Del Pino Jun 2023

Toward One Health: A Spatial Indicator System To Model The Facilitation Of The Spread Of Zoonotic Diseases, Daniel Jato-Espino, Fernando Mayor-Vitoria, Vanessa Moscardó, Fabio Capra-Ribeiro, Leticia Bartolome Del Pino

Faculty Publications

Recurrent outbreaks of zoonotic infectious diseases highlight the importance of considering the interconnections between human, animal, and environmental health in disease prevention and control. This has given rise to the concept of One Health, which recognizes the interconnectedness of between human and animal health within their ecosystems. As a contribution to the One Health approach, this study aims to develop an indicator system to model the facilitation of the spread of zoonotic diseases. Initially, a literature review was conducted using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement to identify relevant indicators related to One Health. The …


A Performer's Guide To Two Song Collections: “Mementos Of Innocence” And “Three Yeats Songs” By Malaysian Composer Chee Yean Wong, Wu Ji Khoo Jun 2023

A Performer's Guide To Two Song Collections: “Mementos Of Innocence” And “Three Yeats Songs” By Malaysian Composer Chee Yean Wong, Wu Ji Khoo

LSU Doctoral Dissertations

Despite the flourishing existence of Asian Art Music for over half a century, relatively little has been done to advance its recognition and prominence. Through this project, the author hopes to shed light on the beauty and richness of Asian Art Music and encourage its inclusion in the repertoire of American classical music. The purpose of this document is to supply a comprehensive performer’s guide to Malaysian composer, Chee Yean Wong’s song collections: “Mementos of Innocence” and “Three Yeats Songs.” The collections feature settings of English poems by Jean Blewett, Christina Rossetti, Edwin C. Ranck, Rabindranath Tagore, and William Butler …


Adaptive Quantum Information Processing In Non-Equilibrium Environments, Arshag Danageozian Jun 2023

Adaptive Quantum Information Processing In Non-Equilibrium Environments, Arshag Danageozian

LSU Doctoral Dissertations

Solid state and condensed matter systems, such as diamond impurities, superconductors, quantum dots, and ion traps, constitute important physical platforms for various applications in quantum information processing (QIP). However, it has consistently been shown that all such modern platforms suffer from non-equilibrium behavior on timescales that are relevant for many important QIP tasks. The causes range from intrinsic non-equilibrium dynamics (e.g. in diamond) to the presence of various impurities with their own internal dynamics (e.g. in superconductors and quantum dots) or variations in the control fields used to stabilize the quantum matter (e.g. in ion traps). When reserving degrees of …


Femme Fatale In Lieder: Songs Of Lorelei By Clara Schumann, Franz Liszt, And Alexander Zemlinsky, Eun Chong Kang Jun 2023

Femme Fatale In Lieder: Songs Of Lorelei By Clara Schumann, Franz Liszt, And Alexander Zemlinsky, Eun Chong Kang

LSU Doctoral Dissertations

The femme fatale, a seductive and dangerous woman, is a popular archetype found in literature, art, and music. In German literature, the character of Lorelei is a well-known example of the femme fatale. She is associated with a steep rock cliff on the Rhine River and, from the cliff, convicted of bewitching men resulting in their murder. This written document focuses on Lorelei as the femme fatale character in German literature as seen in three musical settings by composers Clara Schumann, Franz Liszt, and Alexander Zemlinsky. The document also includes limited musical analyses of and singer’s commentary on …


Empowering Student Success: Unlocking The Potential Of Project-Based Steel Design Education, Aly Mousaad Aly Jun 2023

Empowering Student Success: Unlocking The Potential Of Project-Based Steel Design Education, Aly Mousaad Aly

Faculty Publications

In the pursuit of student success, it is essential to acknowledge that a singular teaching style does not universally cater to all students. The educator's crucial role lies in creating an optimal learning environment that fosters students' endeavors to excel. This endeavor transcends mere classroom success or employment prospects, encompassing a broader impact on societal well-being. An experiential learning approach, where students actively engage in practical tasks, emerges as the most effective mode of instruction. Integrating project-based learning activities into the curriculum holds immense potential for enhancing student learning. Additionally, the utilization of analysis software tools like FTool and STAAD …


Crisis Leadership In Higher Education: A Case Study Of Administrative Responses During A National Pandemic, Katelyn M. Gerlach Jun 2023

Crisis Leadership In Higher Education: A Case Study Of Administrative Responses During A National Pandemic, Katelyn M. Gerlach

LSU Doctoral Dissertations

ABSTRACT

The purpose of this qualitative case study was to explore institutional crisis leadership during a global pandemic in the athletic departments of five mid-major universities located in the Midwest United States, including Blue University, Red University, Green University, Orange University, and Purple University. This study examined the leadership response and decisions surrounding the COVID 19 pandemic. Research leaders consisted of members of the university’s executive leadership team and the athletic departments senior staffs.

I have gathered data in one-on-one, in person and virtual interviews with each member of the executive teams and gained insight and understanding of their leadership …


Reasoning The Voice: Toward A Diagnostic And Prescriptive Technique In The Teaching Of Singing, Carlos E. Santelli Jun 2023

Reasoning The Voice: Toward A Diagnostic And Prescriptive Technique In The Teaching Of Singing, Carlos E. Santelli

LSU Doctoral Dissertations

Voice pedagogy literature often draws a parallel between a doctor’s ability to diagnose illness and prescribe treatment, and a voice teacher’s ability to identify vocal obstacles and design solutions. The core of these parallel procedures lies in an ability to utilize critical reasoning skills within highly specific contexts. Medical literature describes this as “clinical reasoning” and has studied it as a learned process. Voice pedagogy literature has traditionally described this as an innate process which is solely developed through experience. This document broadly examines the ways in which medical literature has broken down clinical reasoning into specific cognitive processes and …


Further Refinement Of An Asd-Subscale For The Childhood Behavior Checklist, Kimberly Ellison Jun 2023

Further Refinement Of An Asd-Subscale For The Childhood Behavior Checklist, Kimberly Ellison

LSU Doctoral Dissertations

The early diagnosis of autism spectrum disorder (ASD) is tied to receiving the earliest possible intervention services that can influence a child’s development (Filipek et al., 1999). There are different measurement tools utilized to aid in the diagnostic assessment process, including broadband behavioral rating scales. The Childhood Behavior Checklist (CBCL; Achenbach & Rescorla, 2001) is a parent/caregiver completed questionnaire about one’s child (typically or atypically developing). The CBCL is one of the most utilized broadband measures at the initial stages of a diagnostic assessment or screening to aid in understanding the symptom presentation (Hyman et al., 2020). Currently, there …


Opinion: How Fear Of Nuclear Winter Has Helped Save The World, So Far, Alan Robock, Lili Xia, Cheryl S. Harrison, Joshua Coupe, Owen B. Toon, Charles G. Bardeen Jun 2023

Opinion: How Fear Of Nuclear Winter Has Helped Save The World, So Far, Alan Robock, Lili Xia, Cheryl S. Harrison, Joshua Coupe, Owen B. Toon, Charles G. Bardeen

Faculty Publications

The direct effects of nuclear war would be horrific, with blasts, fires, and radiation killing and injuring many people. But in 1983, United States and Soviet Union scientists showed that a nuclear war could also produce a nuclear winter, with catastrophic consequences for global food supplies for people far removed from the conflict. Smoke from fires ignited by nuclear weapons exploded on cities and industrial targets would block out sunlight, causing dark, cold, and dry surface conditions, producing a nuclear winter, with surface temperatures below freezing even in summer for years. Nuclear winter theory helped to end the nuclear arms …


Food Insecurity Among Households With Children During The Early Months Of The Covid-19 Pandemic, Bailey Houghtaling, Megan M. Patton-López, Lindsey Haynes-Maslow, Nila Pradhananga, Lauri Andress, T. Elaine Prewitt, Annie Hardison-Moody, Justin D. Shanks, Michelle Grocke-Dewey, Eliza Webber, Denise Holston, Carmen Byker Shanks Jun 2023

Food Insecurity Among Households With Children During The Early Months Of The Covid-19 Pandemic, Bailey Houghtaling, Megan M. Patton-López, Lindsey Haynes-Maslow, Nila Pradhananga, Lauri Andress, T. Elaine Prewitt, Annie Hardison-Moody, Justin D. Shanks, Michelle Grocke-Dewey, Eliza Webber, Denise Holston, Carmen Byker Shanks

Faculty Publications

Understanding impacts of the COVID-19 pandemic among households with children is necessary to design appropriate public health responses that protect food and nutrition security. The objecttive of this research was to understand predictors of food insecurity during the COVID-19 pandemic among households with at least one child (<18 >years), including whether foods reported as out-ofstock were associated with the likelihood of food insecurity. An online survey using validated measures and open-ended questions was distributed to a convenience sample in five states— Louisiana, Montana, North Carolina, Oregon, and West Virginia—during the early months of the COVID-19 pandemic (April through September of …


Simulations Of Intruder-Free X-Ray Transient Absorption And Time-Resolved X-Ray Scattering For Probing Attosecond Electron Dynamics, Mengqi Yang Jun 2023

Simulations Of Intruder-Free X-Ray Transient Absorption And Time-Resolved X-Ray Scattering For Probing Attosecond Electron Dynamics, Mengqi Yang

LSU Doctoral Dissertations

The motion of electrons plays a fundamental role in both physics and chemistry, and capturing such dynamics requires the ability to resolve changes at the attosecond timescale, which is enabled by the advent of ultrashort laser pulses. This dissertation aims to facilitate the interpretation of ultrafast electron dynamics and attosecond spectroscopy by real-time time-dependent density functional theory (RT-TDDFT) simulations. The first part of this dissertation focuses on improving the simulation of X-ray transient absorption spectra (XTAS) with Gaussian basis sets in RT-TDDFT by applying a filter to the transition dipole matrix. Due to the spatial limitation of atom-centered Gaussian functions, …


Development Of A Definition Of Postacute Sequelae Of Sars-Cov-2 Infection, Tanayott Thaweethai, Sarah E. Jolley, Elizabeth W. Karlson, Emily B. Levitan, Bruce Levy, Grace A. Mccomsey, Lisa Mccorkell, Girish N. Nadkarni, Sairam Parthasarathy, Upinder Singh, Tiffany A. Walker, Caitlin A. Selvaggi, Daniel J. Shinnick, Carolin C.M. Schulte, Rachel Atchley-Challenner, Leora I. Horwitz, Andrea S. Foulkes, George A. Alba, Radica Alicic, Natasha Altman, Khamal Anglin, Urania Argueta, Hassan Ashktorab, Gaston Baslet, Ingrid V. Bassett, Lucinda Bateman, Brahmchetna Bedi, Shamik Bhattacharyya, Marie Abele Bind, Andra L. Blomkalns, Hector Bonilla, Patricia A. Bush, Mario Castro, James Chan Jun 2023

Development Of A Definition Of Postacute Sequelae Of Sars-Cov-2 Infection, Tanayott Thaweethai, Sarah E. Jolley, Elizabeth W. Karlson, Emily B. Levitan, Bruce Levy, Grace A. Mccomsey, Lisa Mccorkell, Girish N. Nadkarni, Sairam Parthasarathy, Upinder Singh, Tiffany A. Walker, Caitlin A. Selvaggi, Daniel J. Shinnick, Carolin C.M. Schulte, Rachel Atchley-Challenner, Leora I. Horwitz, Andrea S. Foulkes, George A. Alba, Radica Alicic, Natasha Altman, Khamal Anglin, Urania Argueta, Hassan Ashktorab, Gaston Baslet, Ingrid V. Bassett, Lucinda Bateman, Brahmchetna Bedi, Shamik Bhattacharyya, Marie Abele Bind, Andra L. Blomkalns, Hector Bonilla, Patricia A. Bush, Mario Castro, James Chan

Division of Basic Science Faculty Publications

Importance: SARS-CoV-2 infection is associated with persistent, relapsing, or new symptoms or other health effects occurring after acute infection, termed postacute sequelae of SARS-CoV-2 infection (PASC), also known as long COVID. Characterizing PASC requires analysis of prospectively and uniformly collected data from diverse uninfected and infected individuals. Objective: To develop a definition of PASC using self-reported symptoms and describe PASC frequencies across cohorts, vaccination status, and number of infections. Design, Setting, and Participants: Prospective observational cohort study of adults with and without SARS-CoV-2 infection at 85 enrolling sites (hospitals, health centers, community organizations) located in 33 states plus Washington, DC, …


Nutrition Interventions Addressing Structural Racism: A Scoping Review, Matthew Greene, Bailey Houghtaling, Claire Sadeghzadeh, Molly De Marco, De'jerra Bryant, Randa Morgan, Denise Holston Jun 2023

Nutrition Interventions Addressing Structural Racism: A Scoping Review, Matthew Greene, Bailey Houghtaling, Claire Sadeghzadeh, Molly De Marco, De'jerra Bryant, Randa Morgan, Denise Holston

Faculty Publications

African Americans experience high rates of obesity and food insecurity in part due to structural racism, or overlapping discriminatory systems and practices in housing, education, employment, health care and other settings. Nutrition education and nutrition-focused policy, systems and environmental changes may be able to address structural racism in the food environment. This scoping review aimed to summarise the available literature regarding nutrition interventions for African Americans that address structural racism in the food environment and compare them with the 'Getting to Equity in Obesity Prevention' framework of suggested interventions. An electronic literature search was conducted with the assistance of a …


Behavioral Interventions For Treating Childhood Obesity, William J. Heerman, Ian M. Paul, Amanda E. Staiano Jun 2023

Behavioral Interventions For Treating Childhood Obesity, William J. Heerman, Ian M. Paul, Amanda E. Staiano

Population and Public Health Science Faculty Publications

No abstract provided.


Cycles And Dynamic Correlations Between Agricultural And Stock Markets, Junior E. Betanco Gunera Jun 2023

Cycles And Dynamic Correlations Between Agricultural And Stock Markets, Junior E. Betanco Gunera

LSU Master's Theses

This study conducts two interrelated econometric analyses; it first analyzes the cyclical relationship between stock and commodity markets and second, it studies the dynamic conditional correlation between them. The cyclical analysis uses the bandpass filter proposed by Christiano-Fitzgerald (2003) to isolate the trend component in the long-run relationship of stocks relative to commodity markets. The results show that stock and commodities have alternated in return leadership nine times during the last 151 years, three full cycles (from peak to peak) can be clearly identified, each one with an average duration of 31 years. While the COVID-19 pandemic had little impact …


A Comparison Of Self-Report Measures To Screen For Mental Health Concerns In Youth, Jacob Landon Deboer Jun 2023

A Comparison Of Self-Report Measures To Screen For Mental Health Concerns In Youth, Jacob Landon Deboer

LSU Doctoral Dissertations

Proactive screening for treatable conditions is not a new concept. Instead, screening has been present in the United States since at least the early 1900s. Accordingly, many schools actively screen for academic problems, yet the same attention is not paid to mental health. Past research estimates that one out of five children in the U.S. has a mental health disorder. However, recent research conducted during the COVID-19 pandemic has found these numbers to be increasing. Additional estimates suggest that only one-third of children with a mental health disorder receive treatment. Schools have a role to play in addressing the identification …


Design, Construction, And Testing Of Recombinant Dna-Based Vaccines For Protection Against Salmonella Enterica Subspecies Enterica Serovar Javiana, Ashley Edwards Jun 2023

Design, Construction, And Testing Of Recombinant Dna-Based Vaccines For Protection Against Salmonella Enterica Subspecies Enterica Serovar Javiana, Ashley Edwards

LSU Doctoral Dissertations

In the United States, Salmonella Javiana is among the top 5 most common nontyphoidal Salmonella serotypes, with a 325% increase in infection rate since 1970. Globally, nontyphoidal Salmonella leads to approximately 93.8 million illnesses and 155,000 deaths annually, with disproportionate impacts in developing countries. In the United States alone, these infections lead to over $4 billion in costs, the majority of which are attributed to those expenses incurred from mortalities. The zoonotic nature of nontyphoidal Salmonellae and their ability to survive on and within vegetation mean huge economic burden potential for various agricultural industries as well, especially since some of …


Genome-Wide Coancestry Reveals Details Of Ancient And Recent Male-Driven Reticulation In Baboons, Erik F. Sørensen, R. Alan Harris, Liye Zhang, Muthuswamy Raveendran, Lukas F.K. Kuderna, Jerilyn A. Walker, Jessica M. Storer, Martin Kuhlwilm, Claudia Fontsere, Lakshmi Seshadri, Christina M. Bergey, Andrew S. Burrell, Juraj Bergman, Jane E. Phillips-Conroy, Fekadu Shiferaw, Kenneth L. Chiou, Idrissa S. Chuma, Julius D. Keyyu, Julia Fischer, Marie Claude Gingras, Sejal Salvi, Harshavardhan Doddapaneni, Mikkel H. Schierup, Mark A. Batzer, Clifford J. Jolly, Sascha Knauf, Dietmar Zinner, Kyle K.H. Farh, Tomas Marques-Bonet, Kasper Munch, Christian Roos, Jeffrey Rogers Jun 2023

Genome-Wide Coancestry Reveals Details Of Ancient And Recent Male-Driven Reticulation In Baboons, Erik F. Sørensen, R. Alan Harris, Liye Zhang, Muthuswamy Raveendran, Lukas F.K. Kuderna, Jerilyn A. Walker, Jessica M. Storer, Martin Kuhlwilm, Claudia Fontsere, Lakshmi Seshadri, Christina M. Bergey, Andrew S. Burrell, Juraj Bergman, Jane E. Phillips-Conroy, Fekadu Shiferaw, Kenneth L. Chiou, Idrissa S. Chuma, Julius D. Keyyu, Julia Fischer, Marie Claude Gingras, Sejal Salvi, Harshavardhan Doddapaneni, Mikkel H. Schierup, Mark A. Batzer, Clifford J. Jolly, Sascha Knauf, Dietmar Zinner, Kyle K.H. Farh, Tomas Marques-Bonet, Kasper Munch, Christian Roos, Jeffrey Rogers

Faculty Publications

Baboons (genus Papio) are a morphologically and behaviorally diverse clade of catarrhine monkeys that have experienced hybridization between phenotypically and genetically distinct phylogenetic species. We used high-coverage whole-genome sequences from 225 wild baboons representing 19 geographic localities to investigate population genomics and interspecies gene flow. Our analyses provide an expanded picture of evolutionary reticulation among species and reveal patterns of population structure within and among species, including differential admixture among conspecific populations. We describe the first example of a baboon population with a genetic composition that is derived from three distinct lineages. The results reveal processes, both ancient and recent, …


Association Of Type 2 Diabetes Subgroups With Cognitive Status Without Modification From Lifestyle Intervention, Michael P. Bancks, James Lovato, Ashok Balasubramanyam, Mace Coday, Karen C. Johnson, Medha Munshi, Candida Rebello, Lynne E. Wagenknecht, Mark A. Espeland Jun 2023

Association Of Type 2 Diabetes Subgroups With Cognitive Status Without Modification From Lifestyle Intervention, Michael P. Bancks, James Lovato, Ashok Balasubramanyam, Mace Coday, Karen C. Johnson, Medha Munshi, Candida Rebello, Lynne E. Wagenknecht, Mark A. Espeland

Clinical Research Faculty Publications

Context: Type 2 diabetes is a risk factor for incident dementia but whether risk and treatment/prevention strategies differ by diabetes subgroup is unknown. Objective: We assessed (1) whether specific type 2 diabetes (T2D) subgroups are associated with mild cognitive impairment (MCI) or probable dementia (PD), and (2) whether T2D subgroups modified the association of the Action for Health in Diabetes (Look AHEAD) multidomain intensive lifestyle intervention (ILI) with MCI/PD. Methods: We included 3760 Look AHEAD participants with T2D and overweight or obesity randomly assigned to 10 years of ILI or diabetes support and education. We used k-means clustering techniques with …


Researching Covid To Enhance Recovery (Recover) Adult Study Protocol: Rationale, Objectives, And Design, Leora I. Horwitz, Tanayott Thaweethai, Shari B. Brosnahan, Mine S. Cicek, Megan L. Fitzgerald, Jason D. Goldman, Rachel Hess, S. L. Hodder, Vanessa L. Jacoby, Michael R. Jordan, Jerry A. Krishnan, Adeyinka O. Laiyemo, Torri D. Metz, Lauren Nichols, Rachel E. Patzer, Anisha Sekar, Nora G. Singer, Lauren E. Stiles, Barbara S. Taylor, Shifa Ahmed, Heather A. Algren, Khamal Anglin, Lisa Aponte-Soto, Hassan Ashktorab, Ingrid V. Bassett, Brahmchetna Bedi, Nahid Bhadelia, Christian Bime, Marie Abele C. Bind, Lora J. Black, Andra L. Blomkalns, Hassan Brim, Mario Castro, James Chan Jun 2023

Researching Covid To Enhance Recovery (Recover) Adult Study Protocol: Rationale, Objectives, And Design, Leora I. Horwitz, Tanayott Thaweethai, Shari B. Brosnahan, Mine S. Cicek, Megan L. Fitzgerald, Jason D. Goldman, Rachel Hess, S. L. Hodder, Vanessa L. Jacoby, Michael R. Jordan, Jerry A. Krishnan, Adeyinka O. Laiyemo, Torri D. Metz, Lauren Nichols, Rachel E. Patzer, Anisha Sekar, Nora G. Singer, Lauren E. Stiles, Barbara S. Taylor, Shifa Ahmed, Heather A. Algren, Khamal Anglin, Lisa Aponte-Soto, Hassan Ashktorab, Ingrid V. Bassett, Brahmchetna Bedi, Nahid Bhadelia, Christian Bime, Marie Abele C. Bind, Lora J. Black, Andra L. Blomkalns, Hassan Brim, Mario Castro, James Chan

Division of Basic Science Faculty Publications

Importance SARS-CoV-2 infection can result in ongoing, relapsing, or new symptoms or other health effects after the acute phase of infection; termed post-acute sequelae of SARS-CoV-2 infection (PASC), or long COVID. The characteristics, prevalence, trajectory and mechanisms of PASC are ill-defined. The objectives of the Researching COVID to Enhance Recovery (RECOVER) Multi-site Observational Study of PASC in Adults (RECOVER-Adult) are to: (1) characterize PASC prevalence; (2) characterize the symptoms, organ dysfunction, natural history, and distinct phenotypes of PASC; (3) identify demographic, social and clinical risk factors for PASC onset and recovery; and (4) define the biological mechanisms underlying PASC pathogenesis. …


Impact Of Zein And Lignin-Plga Biopolymer Nanoparticles Used As Pesticide Nanocarriers On Soybean Growth And Yield Under Field Conditions, Colin A.R. Bonser, Jaya Borgatta, Jason C. White, Carlos E. Astete, Cristina M. Sabliov, Jeffrey A. Davis Jun 2023

Impact Of Zein And Lignin-Plga Biopolymer Nanoparticles Used As Pesticide Nanocarriers On Soybean Growth And Yield Under Field Conditions, Colin A.R. Bonser, Jaya Borgatta, Jason C. White, Carlos E. Astete, Cristina M. Sabliov, Jeffrey A. Davis

Faculty Publications

Nanoparticles are being utilized in agriculture as fertilizers, pesticides, and agrochemical-carriers. Designed to be biocompatible and degradable, biopolymer nanoparticles were developed as an alternative to metallic nanoparticles, and though safe-by-design, polymeric nanoparticles must be field-tested prior to largescale use. Several field studies were conducted to observe detrimental effects of biopolymer nanoparticles on plant growth and yield using soybean, Glycine max (L.) Merr., as a model system. Biopolymer nanoparticles made from lignin or zein were applied as seed treatments to soybean seeds or as foliar sprays (zein only) to soybean plants. Studies using biopolymer nanoparticle seed treatments (nano-STs) measured the germination …