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Articles 1711 - 1740 of 4162
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Evaluation Of Ammonia Volatilization And Zinc Nutrition Of Experimental Zinc Sulfate Coated Urea Fertilizers In A Drill-Seeded Delayed Flood Rice Production System, Nutifafa Adotey
LSU Doctoral Dissertations
Approaches in controlling nitrogen (N) loss from preflood fertilizer applications in delayed flood rice (Oryza stiva) production in the mid-southern U.S.A. typically involves treating urea with urease inhibitors like N-(n-butyl) thiophosphoric triamide (NBPT). Limited research exists on managing N utilizing the combined effects of treating urea with a urease inhibitor and subsequently adding a physical zinc (Zn) sulfate coating. Zinc deficiency is also a major soil fertility constraint in flooded rice production. The objectives of this study were to: (i) determine the ammonia volatilization potential of experimental zinc sulfate coated urea (ZSCU) fertilizers on four rice soils in a controlled …
Parenting The Gifted And Talented Child: A Qualitative Inquiry Of The Perceptions Of Mothers Regarding Their Unique Experiences In Raising Gifted And Talented Children, Mary F. Hidalgo
LSU Doctoral Dissertations
The lived experiences of mothers raising gifted and talented (G/T) children can differ from the lived experiences of mothers raising non-G/T children, and these unique experiences may spark concern, impact choices, and exacerbate stress and anxiety. The purpose of this study was to gather data in order to illustrate the distinctly defining experiences and perceptions of mothers currently raising G/T children as well as to consider both the internal and external factors affecting and influencing perspectives and self-efficacy. Utilizing a qualitative, case study research design approach, the researcher conducted interviews with eight volunteer mothers willing to share their thoughts and …
African-American Single Mothers' Experiences While Furthering Their Education, Kimberly Rayshun James
African-American Single Mothers' Experiences While Furthering Their Education, Kimberly Rayshun James
LSU Doctoral Dissertations
The government as expressed the importance of a post-secondary education for career advancement, and they have displayed the income increase and rate of return between post-secondary degrees and a high school diploma. Due to the benefits of income and career advancement with a post-secondary education, more women are enrolling in colleges and universities, especially African-American single mothers; however, the graduation rate with this group is low. Little research concentrated on the experiences of African-American single mothers while obtaining their post-secondary education, and more research has focused on the connection between the women and stereotypes that followed the race since slavery. …
Exploring Intermedia Agenda Setting Effects Of Last Week Tonight With John Oliver, Andrew Abad
Exploring Intermedia Agenda Setting Effects Of Last Week Tonight With John Oliver, Andrew Abad
LSU Master's Theses
The HBO television program Last Week Tonight with John Oliver is a new and unique take on the typical political comedy show popularized by programs like The Daily Show and The Colbert Report. Uninterrupted by commercial breaks and with full creative control, host John Oliver and his team spend 30 minutes on Sunday nights discussing a typically underreported story at length, abandoning the monologue and interview portions reminiscent of traditional political comedy shows in favor of a long-form style investigation into a particular issue or topic. The main segment of each episode is then uploaded to the social media website, …
An Integrated Approach To Ambrosia Beetle Management In Ornamental Tree Nurseries: Biology Of And Control Measures For Exotic Xyleborina, Christopher Werle
An Integrated Approach To Ambrosia Beetle Management In Ornamental Tree Nurseries: Biology Of And Control Measures For Exotic Xyleborina, Christopher Werle
LSU Doctoral Dissertations
Ambrosia beetles have been a challenge to profitable nursery production for decades, with management recommendations focused on population monitoring and properly-timed insecticidal applications. Beetles disperse from forests starting in early spring, but few studies have determined the extent of this flight period, or how far they will fly into a nursery. And while the use of semiochemicals by ambrosia beetles has been widely examined, their use of visual cues including colors represents another gap in our knowledge. In addition to these under-studied behavioral traits, the available chemical control measures for ambrosia beetles are not completely effective, and repeated applications become …
Combining Forage And Cover Crop Benefits From Cool-Season Annuals In The Southeastern United States, Dustin John Smith
Combining Forage And Cover Crop Benefits From Cool-Season Annuals In The Southeastern United States, Dustin John Smith
LSU Master's Theses
Cow-calf operations in the southeastern United States (U.S.) are based on warm-season perennial grass pastures. Stored forage feeding during the non-grazing season constitutes more than half of a cattle operation’s annual expenses. Cool-season annuals can extend the grazing season, thereby reducing stored forage feeding. A two-year field trial was conducted to determine the forage potential of a variety of crops commonly used as winter cover crops in the southeastern U.S. The ten cover crop treatments included seven monocultures (annual ryegrass [Lolium multiflorum], rye [Secale cereal], oats [Avena sativa], triticale [Triticale hexaploide], tillage radish [Raphanus sativus], hairy vetch [Vicia villosa], crimson …
Effects Of Glyphosate On Soybean Nutrition, Endophytic Colonization By Cercospora Cf. Flagellaris And Development Of Cercospora Leaf Blight, Teddy Garcia Aroca
Effects Of Glyphosate On Soybean Nutrition, Endophytic Colonization By Cercospora Cf. Flagellaris And Development Of Cercospora Leaf Blight, Teddy Garcia Aroca
LSU Master's Theses
Glyphosate (Roundup®, Monsanto, Inc., St. Louis, MO) is the most widely used herbicide in the world because of its broad spectrum and its efficacy in controlling annual broadleaf weeds and undesired grasses. The effect of glyphosate on mineral nutrition and plant diseases has been an important topic during the past decade, because of its controversial effects on plant mineral nutrition. In order to test the hypothesis that glyphosate affects soybean mineral nutrition, and therefore predisposes soybean to Cercospora leaf blight, six glyphosate-resistant (GR) soybean varieties were either not treated or treated with glyphosate in field experiments. Plants were then evaluated …
Successful Aging In Oldest-Old Adults: Role Of Physical And Social Factors, Katie Elizabeth Stanko
Successful Aging In Oldest-Old Adults: Role Of Physical And Social Factors, Katie Elizabeth Stanko
LSU Master's Theses
Successful aging, increasing in chronological age while maintaining health, is related to a multitude of factors including social and physical behaviors. Older adults may report that they are aging successfully while biomedical outcomes suggest otherwise. In the present study, sociodemographic characteristics, social engagement, physical activity in relation to frailty and health-related quality of life (HR QoL) were examined using a lifespan sample of adults (N = 732) from the Louisiana Healthy Aging Study (LHAS). Four age groups were compared: younger (21-44 years), middle-aged (45-64 years), older (65-84 years), and oldest-old adults (85 to 101 years). A main effect of age …
Effects Of Truck Based Ultra-Low Volume Mosquito Adulticides On Honey Bees (Apis Mellifera) In A Real World Scenario, Vivek Pokhrel
Effects Of Truck Based Ultra-Low Volume Mosquito Adulticides On Honey Bees (Apis Mellifera) In A Real World Scenario, Vivek Pokhrel
LSU Master's Theses
Honey bees are crucial pollinators for many economically important fruit crops. The recent honey bee colony decline in the United States and other regions of the world has caused concern among commercial beekeepers, research groups, the government, and the general public. The role of pesticides in recent honey bee declines has not been fully determined. In Louisiana, it is a common practice to spray truck based ultra-low volume mosquito adulticides in Integrated Mosquito Management Programs to control mosquitoes and minimize the risk of vector borne viruses such as West Nile, chikungunya, and Zika. This study measured the effects of truck …
In Vitro Investigation On Therapeutic Potential Of Juglone, A Naphthoquinone From Walnuts Against Pancreatic Cancer, Namrata Karki
In Vitro Investigation On Therapeutic Potential Of Juglone, A Naphthoquinone From Walnuts Against Pancreatic Cancer, Namrata Karki
LSU Doctoral Dissertations
Juglone, a naphthoquinone found in Juglandaceae family, which includes black walnut, European walnut, and butter nut possess various biological activities. The anti-cancer properties of juglone has been reported; however, the effect of juglone in pancreatic cancer (PC) has not been elucidated yet. PC is an aggressive lethal, highly metastatic disease associated with poor prognosis and high mortality rate. PC is usually diagnosed in advanced stage and chemotherapy is provided as a first line of treatment. The de novo chemoresistance that develops with chemotherapeutic treatment creates a critical need for identification of novel therapeutic agents for effectively targeting the disease. The …
Integrated Methods For Controlling Gastrointestinal Nematode Infections In Ewes And Lambs, Sarah Tammy Nicole Keeton
Integrated Methods For Controlling Gastrointestinal Nematode Infections In Ewes And Lambs, Sarah Tammy Nicole Keeton
LSU Doctoral Dissertations
Gastrointestinal nematode (GIN) parasites cause extensive damage to small ruminants, and Haemonchus contortus is a major concern to production worldwide. With the development of GIN resistance to anthelmintics, alternative strategies for control are needed. The major component of this study compared two strategies for effect on animal health and changes in GIN population. One flock of ewes and lambs (Strategy 1, S1) employed targeted selective treatment (TST) with an anthelmintic based on FAMACHA score, and one flock (Strategy 2, S2) employed sericea lespedeza (SL) supplement feeding and TST with copper oxide wire particles (COWP) based on FAMACHA score. S1 ewes/lambs …
Human Norovirus In Artificial And Environmental Marine Water: Development Of Antibody Based Rapid Methods, Morgan Maite
Human Norovirus In Artificial And Environmental Marine Water: Development Of Antibody Based Rapid Methods, Morgan Maite
LSU Doctoral Dissertations
Norovirus (NoV) is the principal cause of viral gastroenteritis in the United States. It has been linked to filter-feeding molluscan shellfish, that bioaccumulate the virus from contaminated surrounding waters. The consumption of raw or undercooked contaminated oysters may result in acute gastroenteritis. We investigated the occurrence of NoV GI and GII and microbial indicators of fecal contamination in oysters and harvesting water from areas along the Louisiana Gulf Coast. We developed a filtration and concentration method for the detection of NoV from oyster harvesting waters. Lastly, this body of work compares commonly used molecular techniques (RT-PCR) and a commercial enzyme …
Silicon Fertilization In Rice:Establishment Of Critical Silicon Level And Its Impact On Availability Of Nutrients In Soils Of Louisiana, Wooiklee Sundayboy Paye
Silicon Fertilization In Rice:Establishment Of Critical Silicon Level And Its Impact On Availability Of Nutrients In Soils Of Louisiana, Wooiklee Sundayboy Paye
LSU Master's Theses
While silicon (Si) fertilization is widely practiced in paddy rice production, the establishment of critical soil Si levels has remained understudied. This study was undertaken to: 1) determine the critical soil Si level for rice production in Louisiana using different extraction procedures, and 2) document the relationship between plant-available Si and select essential plant nutrients in soil and their uptake by rice. Field trials were established at 12 sites across Louisiana from 2013 to 2015. Si was applied as silicate slag (SiO3, 14% Si) at the rates of 0, 1, 2, 4, 6, and 8 Mg ha-1. Agricultural lime was …
Vitamin E Conjugates, And Their Uses As Antioxidants And Prodrug Delivery Vehicles, Cristina M. Sabliov, Carlos E. Astete, David Spivak
Vitamin E Conjugates, And Their Uses As Antioxidants And Prodrug Delivery Vehicles, Cristina M. Sabliov, Carlos E. Astete, David Spivak
College of Engineering Patents
Tocopherol conjugates are disclosed that are useful as antioxidants or as pro-drug delivery vehicles. The conjugates are amphiphilic, and tend to localize at the interface between water domains and lipid domains. A prototype embodiment disclosed is an alpha tocopherol-linker-carnosine conjugate that has been designated VECAR.
Dna-Binding Motif Of The Imprinted Transcription Factor Peg3, Suman Lee, An Ye, Joomyeong Kim
Dna-Binding Motif Of The Imprinted Transcription Factor Peg3, Suman Lee, An Ye, Joomyeong Kim
Faculty Publications
© 2015 Lee et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Peg3 is an imprinted gene that is predicted to encode a DNA-binding zinc finger protein. This was previously demonstrated through Chromatin ImmunoPrecipitation-based Sequencing experiments. In the current study, we reanalyzed the previous ChIP-Seq results and further characterized the DNA-binding motif of PEG3. According to the results, PEG3 binds to the promoters and enhancers of a subset of genes that are closely …
Faculty Senate Newsletter, Holiday 2015, Louisiana State University And Agricultural & Mechanical College
Faculty Senate Newsletter, Holiday 2015, Louisiana State University And Agricultural & Mechanical College
LSU Faculty Senate Publications
Message from President: At the end of the LSU-Texas A&M game, television captured Les Miles standing in the embrace of a burly player, insistently singing the LSU alma mater. Any comedy that might have inhered in such an effort at roughhouse opera deteriorated under the impression that the performance was sending a bullying message to LSU officials about the alleged high level of public support for a coach rumored to be fighting for his job. By exploiting a musical component from the sacraments of the academic community for exclusively personal ends, the beleaguered coach helped everyone to understand what has …
Breeding Technologies In U.S. Meat Goat Production: Who Are The Adopters And How Does Adoption Impact Productivity?, Jeffrey Gillespie, Berdikul Qushim, Narayan Nyaupane, Kenneth Mcmillin
Breeding Technologies In U.S. Meat Goat Production: Who Are The Adopters And How Does Adoption Impact Productivity?, Jeffrey Gillespie, Berdikul Qushim, Narayan Nyaupane, Kenneth Mcmillin
Faculty Publications
Copyright 2015 Northeastern Agricultural and Resource Economics Association. Adoption of advanced breeding technologies and management practices (BTMP) in U.S. meat goat production and their impact were examined. Adopters generally had larger-scale operations, used rotational grazing and/or dry lot systems, and sold larger percentages of animals for breeding and show purposes. Farmer demographics and farm variables also influenced adoption. Complementarity of adoption was found-adopters of one BTMP tended to adopt other BTMPs. Measures of productivity and profitability were not affected by adoption. Goat breed, farmer experience, production system used, and specialization influenced productivity, and farm size had the greatest influence on …
Examining Louisiana State University College Of Agriculture Students’ Perceived Motivators And Barriers To Participation In International Experiences, J. C. Bunch, J. Joey Blackburn, Shelli Dan Jean, Kristin E. Stair, Leslie D. Blanchard
Examining Louisiana State University College Of Agriculture Students’ Perceived Motivators And Barriers To Participation In International Experiences, J. C. Bunch, J. Joey Blackburn, Shelli Dan Jean, Kristin E. Stair, Leslie D. Blanchard
Faculty Publications
© 2015, Assoc. Int. Agricultural and Extension Education. All rights reserved. In an effort to internationalize higher education and produce globally competent professionals, many universities have increased the time and financial assets put toward promoting an international experience (IE). Research supports using an IE to supplement international education efforts and help students develop the global perspective and experience needed to succeed in the workplace. The purpose of this study was to determine College of Agriculture (CoA) students’ perceptions of IE participation, and identify factors that CoA students perceived as barriers and motivators to participation in an IE. CoA students were …
Mathematics Library News 14, Aaron Lercher
Novel Mode Of Defective Neural Tube Closure In The Non-Obese Diabetic (Nod) Mouse Strain, J. Michael Salbaum, Claudia Kruger, Jacalyn Macgowan, Nils J. Herion, David Burk, Claudia Kappen
Novel Mode Of Defective Neural Tube Closure In The Non-Obese Diabetic (Nod) Mouse Strain, J. Michael Salbaum, Claudia Kruger, Jacalyn Macgowan, Nils J. Herion, David Burk, Claudia Kappen
Faculty Publications
Failure to close the neural tube results in birth defects, with severity ranging from spina bifida to lethal anencephaly. Few genetic risk factors for neural tube defects are known in humans, highlighting the critical role of environmental risk factors, such as maternal diabetes. Yet, it is not well understood how altered maternal metabolism interferes with embryonic development, and with neurulation in particular. We present evidence from two independent mouse models of diabetic pregnancy that identifies impaired migration of nascent mesodermal cells in the primitive streak as the morphogenetic basis underlying the pathogenesis of neural tube defects. We conclude that perturbed …
Fetal Programming In Meat Production, Min Du, Bo Wang, Xing Fu, Qiyuan Yang, Mei Jun Zhu
Fetal Programming In Meat Production, Min Du, Bo Wang, Xing Fu, Qiyuan Yang, Mei Jun Zhu
Faculty Publications
© 2015 Elsevier Ltd. Nutrient fluctuations during the fetal stage affects fetal development, which has long-term impacts on the production efficiency and quality of meat. During the early development, a pool of mesenchymal progenitor cells proliferate and then diverge into either myogenic or adipogenic/fibrogenic lineages. Myogenic progenitor cells further develop into muscle fibers and satellite cells, while adipogenic/fibrogenic lineage cells develop into adipocytes, fibroblasts and resident fibro-adipogenic progenitor cells. Enhancing the proliferation and myogenic commitment of progenitor cells during fetal development enhances muscle growth and lean production in offspring. On the other hand, promoting the adipogenic differentiation of adipogenic/fibrogenic progenitor …
Cellular And Molecular Remodeling Of Inguinal Adipose Tissue Mitochondria By Dietary Methionine Restriction, Yuvraj N. Patil, Kelly N. Dille, David H. Burk, Cory C. Cortez, Thomas W. Gettys
Cellular And Molecular Remodeling Of Inguinal Adipose Tissue Mitochondria By Dietary Methionine Restriction, Yuvraj N. Patil, Kelly N. Dille, David H. Burk, Cory C. Cortez, Thomas W. Gettys
Faculty Publications
© 2015 Elsevier Inc. Dietary methionine restriction (MR) produces a coordinated series of biochemical and physiological responses that improve biomarkers of metabolic health, increase energy expenditure, limit fat accretion and improve overall insulin sensitivity. Inguinal white adipose tissue (IWAT) is a primary target and site of action where the diet initiates transcriptional programs linked to enhancing both synthesis and oxidation of lipid. Using a combination of ex vivo approaches to assess dietary effects on cell morphology and function, we report that dietary MR produced a fourfold increase in multilocular, UCP1-expressing cells within this depot in conjunction with significant increases in …
Improving Healthspan Via Changes In Gut Microbiota And Fermentation, Michael J. Keenan, Maria L. Marco, Donald K. Ingram, Roy J. Martin
Improving Healthspan Via Changes In Gut Microbiota And Fermentation, Michael J. Keenan, Maria L. Marco, Donald K. Ingram, Roy J. Martin
Faculty Publications
Dietary resistant starch impact on intestinal microbiome and improving healthspan is the topic of this review. In the elderly population, dietary fiber intake is lower than recommended. Dietary resistant starch as a source of fiber produces a profound change in gut microbiota and fermentation in animal models of aging. Dietary resistant starch has the potential for improving healthspan in the elderly through multiple mechanisms as follows: (1) enhancing gut microbiota profile and production of short-chain fatty acids, (2) improving gut barrier function, (3) increasing gut peptides that are important in glucose homeostasis and lipid metabolism, and (4) mimicking many of …
Ethanol Enhances Arsenic-Induced Cyclooxygenase-2 Expression Via Both Nfat And Nf-Κb Signalings In Colorectal Cancer Cells, Lei Wang, John Andrew Hitron, James T.F. Wise, Young Ok Son, Ram Vinod Roy, Donghern Kim, Jin Dai, Poyil Pratheeshkumar, Zhuo Zhang, Mei Xu, Jia Luo, Xianglin Shi
Ethanol Enhances Arsenic-Induced Cyclooxygenase-2 Expression Via Both Nfat And Nf-Κb Signalings In Colorectal Cancer Cells, Lei Wang, John Andrew Hitron, James T.F. Wise, Young Ok Son, Ram Vinod Roy, Donghern Kim, Jin Dai, Poyil Pratheeshkumar, Zhuo Zhang, Mei Xu, Jia Luo, Xianglin Shi
Faculty Publications
Arsenic is a known carcinogen to humans, and chronic exposure to environmental arsenic is a worldwide health concern. As a dietary factor, ethanol carries a well-established risk for malignancies, but the effects of co-exposure to arsenic and ethanol on tumor development are not well understood. In the present study, we hypothesized that ethanol would enhance the function of an environmental carcinogen such as arsenic through increase in COX-2 expression. Our in vitro results show that ethanol enhanced arsenic-induced COX-2 expression. We also show that the increased COX-2 expression associates with intracellular ROS generation, up-regulated AKT signaling, with activation of both …
Effects Of Oil-Contaminated Sediments On Submerged Vegetation: An Experimental Assessment Of Ruppia Maritima, Charles W. Martin, Lauris O. Hollis, R. Eugene Turner
Effects Of Oil-Contaminated Sediments On Submerged Vegetation: An Experimental Assessment Of Ruppia Maritima, Charles W. Martin, Lauris O. Hollis, R. Eugene Turner
Faculty Publications
Oil spills threaten the productivity of ecosystems through the degradation of coastal flora and the ecosystem services these plants provide. While lab and field investigations have quantified the response of numerous species of emergent vegetation to oil, the effects on submerged vegetation remain uncertain. Here, we discuss the implications of oil exposure for Ruppia maritima, one of the most common species of submerged vegetation found in the region affected by the recent Deepwater Horizon oil spill. We grew R. maritima in a range of manipulated sediment oil concentrations: 0, 0.26, 0.53, and 1.05 mL oil /L tank volume, and tracked …
Genetics, Synergists, And Age Affect Insecticide Sensitivity Of The Honey Bee, Apis Mellifera, Frank D. Rinkevich, Joseph W. Margotta, Jean M. Pittman, Robert G. Danka, Matthew R. Tarver, James A. Ottea, Kristen B. Healy
Genetics, Synergists, And Age Affect Insecticide Sensitivity Of The Honey Bee, Apis Mellifera, Frank D. Rinkevich, Joseph W. Margotta, Jean M. Pittman, Robert G. Danka, Matthew R. Tarver, James A. Ottea, Kristen B. Healy
Faculty Publications
The number of honey bee colonies in the United States has declined to half of its peak level in the 1940s, and colonies lost over the winter have reached levels that are becoming economically unstable. While the causes of these losses are numerous and the interaction between them is very complex, the role of insecticides has garnered much attention. As a result, there is a need to better understand the risk of insecticides to bees, leading to more studies on both toxicity and exposure. While much research has been conducted on insecticides and bees, there have been very limited studies …
High Blood Pressure In Sub-Saharan Africa: The Urgent Imperative For Prevention And Control, Justin B. Echouffo-Tcheugui, Andre P. Kengne, Sebhat Erqou, Richard S. Cooper
High Blood Pressure In Sub-Saharan Africa: The Urgent Imperative For Prevention And Control, Justin B. Echouffo-Tcheugui, Andre P. Kengne, Sebhat Erqou, Richard S. Cooper
Faculty Publications
No abstract provided.
Ecological Networks In Stored Grain: Key Postharvest Nodes For Emerging Pests, Pathogens, And Mycotoxins, John F. Hernandez Nopsa, Gregory J. Daglish, David W. Hagstrum, John F. Leslie, Thomas W. Phillips, Caterina Scoglio, Sara Thomas-Sharma, Gimme H. Walter, Karen A. Garrett
Ecological Networks In Stored Grain: Key Postharvest Nodes For Emerging Pests, Pathogens, And Mycotoxins, John F. Hernandez Nopsa, Gregory J. Daglish, David W. Hagstrum, John F. Leslie, Thomas W. Phillips, Caterina Scoglio, Sara Thomas-Sharma, Gimme H. Walter, Karen A. Garrett
Faculty Publications
Wheat is at peak quality soon after harvest. Subsequently, diverse biota use wheat as a resource in storage, including insects and mycotoxin-producing fungi. Transportation networks for stored grain are crucial to food security and provide a model system for an analysis of the population structure, evolution, and dispersal of biota in networks. We evaluated the structure of rail networks for grain transport in the United States and Eastern Australia to identify the shortest paths for the anthropogenic dispersal of pests and mycotoxins, as well as the major sources, sinks, and bridges for movement. We found important differences in the risk …
Oat Consumption Reduced Intestinal Fat Deposition And Improved Health Span In Caenorhabditis Elegans Model, Chenfei Gao, Zhanguo Gao, Frank L. Greenway, Jeffrey H. Burton, William D. Johnson, Michael J. Keenan, Frederick M. Enright, Roy J. Martin, Yi Fang Chu, Jolene Zheng
Oat Consumption Reduced Intestinal Fat Deposition And Improved Health Span In Caenorhabditis Elegans Model, Chenfei Gao, Zhanguo Gao, Frank L. Greenway, Jeffrey H. Burton, William D. Johnson, Michael J. Keenan, Frederick M. Enright, Roy J. Martin, Yi Fang Chu, Jolene Zheng
Faculty Publications
© 2015 The Authors. In addition to their fermentable dietary fiber and the soluble β-glucan fiber, oats have unique avenanthramides that have anti-inflammatory and antioxidant properties that reduce coronary heart disease in human clinical trials. We hypothesized that oat consumption will increase insulin sensitivity, reduce body fat, and improve health span in Caenorhabditis elegans through a mechanism involving the daf-2 gene, which codes for the insulin/insulin-like growth factor-1-like receptor, and that hyperglycemia will attenuate these changes. Caenorhabditis elegans wild type (N2) and the null strains sir-2.1, daf-16, and daf-16/daf-2 were fed Escherichia coli (OP50) and oat flakes (0.5%, 1.0%, or …
Directional Dominance On Stature And Cognition In Diverse Human Populations, Peter K. Joshi, Tonu Esko, Hannele Mattsson, Niina Eklund, Ilaria Gandin, Teresa Nutile, Anne U. Jackson, Claudia Schurmann, Albert V. Smith, Weihua Zhang, Yukinori Okada, Alena Stančáková, Jessica D. Faul, Wei Zhao, Traci M. Bartz, Maria Pina Concas, Nora Franceschini, Stefan Enroth, Veronique Vitart, Stella Trompet, Xiuqing Guo, Daniel I. Chasman, Jeffrey R. O'Connel, Tanguy Corre, Suraj S. Nongmaithem, Yuning Chen, Massimo Mangino, Daniela Ruggiero, Michela Traglia, Aliki Eleni Farmaki, Tim Kacprowski, Andrew Bjonnes, Ashley Van Der Spek
Directional Dominance On Stature And Cognition In Diverse Human Populations, Peter K. Joshi, Tonu Esko, Hannele Mattsson, Niina Eklund, Ilaria Gandin, Teresa Nutile, Anne U. Jackson, Claudia Schurmann, Albert V. Smith, Weihua Zhang, Yukinori Okada, Alena Stančáková, Jessica D. Faul, Wei Zhao, Traci M. Bartz, Maria Pina Concas, Nora Franceschini, Stefan Enroth, Veronique Vitart, Stella Trompet, Xiuqing Guo, Daniel I. Chasman, Jeffrey R. O'Connel, Tanguy Corre, Suraj S. Nongmaithem, Yuning Chen, Massimo Mangino, Daniela Ruggiero, Michela Traglia, Aliki Eleni Farmaki, Tim Kacprowski, Andrew Bjonnes, Ashley Van Der Spek
Faculty Publications
Homozygosity has long been associated with rare, often devastating, Mendelian disorders, and Darwin was one of the first to recognize that inbreeding reduces evolutionary fitness. However, the effect of the more distant parental relatedness that is common in modern human populations is less well understood. Genomic data now allow us to investigate the effects of homozygosity on traits of public health importance by observing contiguous homozygous segments (runs of homozygosity), which are inferred to be homozygous along their complete length. Given the low levels of genome-wide homozygosity prevalent in most human populations, information is required on very large numbers of …