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The Apologia Of Franchino Gafurio: A Critical Edition And Translation, Patrick Joseph Kaufman Jan 2007

The Apologia Of Franchino Gafurio: A Critical Edition And Translation, Patrick Joseph Kaufman

LSU Master's Theses

Franchino Gafurio’s Apologia (Turin, 1520) is one musical treatise in a series of works that constituted the famous “pamphlet war” between he and Giovanni Spataro. The dispute originated with the publication of Bartholomeo Ramis de Pareia’s Musica practica (Bologna, 1482). Unconventional and unapologetically critical, Ramis rejected venerated musical traditions in an attempt to align music theory with contemporary music practice. He opposed the Pythagorean division of the monochord and Guidonian solmization syllables, and instead proposed a division which produced pure thirds, and a solmization system based on the octave. His iconoclastic proposals and his highly sarcastic tone called forth a …


Korean Hurricane Media Discourse Analysis, Youngae Lee Jan 2007

Korean Hurricane Media Discourse Analysis, Youngae Lee

LSU Master's Theses

Presented within this thesis, I have analyzed a particular TV broadcast news discourse called Korean Hurricane Media Discourse (KHMD), which was presented online from YTN, a Korean cable TV news station. The data presents the topic of the Korean refugees who were forced to evacuate to Baton Rouge from New Orleans, after facing the destructions of Hurricane Katrina on August 2005. The methods are Ron Scollon’s TV news frames (1998), van Dijk’s superstructure (1988a and 1988b) and macrostructure (1980), Allan Bell’s news structure (1991), Dell Hymes’s SPEAKING model (1974), and Erving Goffman’s frameworks (1986). Since KHMD is a spoken, plannable …


Intracellular Lipids In Bos Indicus And Box Taurus Oocytes, Casey Bryant Ballard Jan 2007

Intracellular Lipids In Bos Indicus And Box Taurus Oocytes, Casey Bryant Ballard

LSU Master's Theses

It has been proposed that Bos indicus when compared with Bos taurus embryos are more sensitive to cryopreservation procedures due to higher intracellular lipid content of the embryos. With cyropreservation of Bos indicus embryos increasing for export, it is essential to improve the viability of these cryopreserved embryos. In Experiment I, M-II oocytes from mice, pigs and cows were subjected to two different procedures to evaluate lipid content. The lipid content present in pig oocytes was significantly (P<0.05) higher when compared with mouse and cow oocytes. Pig oocytes had a lower settling point in the sucrose buoyant density gradient and higher Nile Red units, which indicated higher lipids present in the oocytes. In Experiment II, it was determined that M-II oocytes aspirated from superstimulated Brahman donors were significantly higher (P<0.05) in lipid content compared with English breed donors. The lipid content present in Brahman oocytes was higher when compared with English breeds when tested with a sucrose buoyant density gradient and Nile Red staining. In addition, donor females with higher body condition scores were significantly (P<0.05) higher in oocyte lipid content when compared with donor females of lower body condition scores. Furthermore, animal body condition scores, cholesterol and triglyceride levels prior to oocyte aspiration may be indicators of intracellular lipids in the oocytes and embryos. To our knowledge, this is the first report that evaluated intracellular lipid content of M-II oocytes of different beef breed types using a sucrose buoyant density gradient and Nile Red staining.


The Effects Of Recq, Uvrd, And Recd Mutants Of Deinococcus Radiodurans On Resistance To Dna Damaging Agents, Stephannie Gauthier Ruiz Jan 2007

The Effects Of Recq, Uvrd, And Recd Mutants Of Deinococcus Radiodurans On Resistance To Dna Damaging Agents, Stephannie Gauthier Ruiz

LSU Master's Theses

The genes encoding the putative nuclease RecD and the helicase RecQ were deleted from Deinococcus radiodurans R1 and replaced with constructs conferring hygromycin or spectinomycin resistance. The ÄrecD and ÄrecQ strains were found to be similar to wild type R1 strain in resistance to gamma irradiation. In contrast to the single mutant strains, the ÄuvrD, ÄrecQ double mutant was found to be extremely radiation sensitive, indicating that these proteins share a complementary activity needed for radioresistance. ÄrecD mutants have higher transformation efficiencies than the wild type R1 strains, suggesting an association of RecD with nucleases that degrade single stranded DNA. …


Direct White Sugar Production: Optimization And Chemical Regeneration Of Fixed-Bed Activated Carbon Adsorbers, Raul Alejandro Cortes Jan 2007

Direct White Sugar Production: Optimization And Chemical Regeneration Of Fixed-Bed Activated Carbon Adsorbers, Raul Alejandro Cortes

LSU Master's Theses

A system for the direct production of white sugar from clarified sugar cane juice in a raw sugar factory has been developed at the Audubon Sugar Institute. This Direct White Sugar Production (DWiSP) system employs a series of columns packed with adsorbent media. Activated carbon is used in the first column(s) as a filter and bulk decolorizer. Ion exchange resins are then used to remove ash and remaining color. Batch testing was performed in order to determine equilibrium parameters. An analytical model was utilized in conjunction with column loading tests to determine dynamic characteristics of the carbon adsorber for use …


A Performer's Guide To Ross Lee Finney's Song Cycle Chamber Music, Joseph Charles Perniciaro Jan 2007

A Performer's Guide To Ross Lee Finney's Song Cycle Chamber Music, Joseph Charles Perniciaro

LSU Major Papers

Ross Lee Finney (1906-1997), significant American composer and pedagogue, published five works for solo voice and piano within his catalogue of genres and styles. Though composed in 1951, Finney’s setting of Chamber Music, to James Joyce’s texts by the same title, remained unpublished until 1985. This song cycle, Finney’s last published solo vocal work, will be the focus of this document and subsequent lecture recital. The purpose of this study will be to examine seventeen of the thirty-six songs from the cycle and provide performance suggestions. The written document is comprised of five chapters: Chapter One provides biographical information and …


Who Speaks And Who Listens? Genre, Gender, And Memory In Holocaust Discourses, Lisa A. Costello Jan 2007

Who Speaks And Who Listens? Genre, Gender, And Memory In Holocaust Discourses, Lisa A. Costello

LSU Doctoral Dissertations

The Holocaust discourses examined in Who Speaks and Who Listens? Genre, Gender and Memory in Holocaust Discourses perform writing that does something through the presentation of meaningful content and its interaction with the process of the writing act. These discourses are utterances necessarily wedged between the past and the future—between the fear that the traumatic past of the Holocaust recedes too much and the concern with what might become of this past for the generations that follow. The theory of performative memorialization describes how multiple discourses of the Holocaust engage with each other and with the audiences that receive and …


Sugarcane Tasseling Under Artificial Photoperiod Conditions As Affected By Nitrogen Rate And Temperature, Christopher Michael Laborde Jan 2007

Sugarcane Tasseling Under Artificial Photoperiod Conditions As Affected By Nitrogen Rate And Temperature, Christopher Michael Laborde

LSU Doctoral Dissertations

Optimizing flowering in the LSU AgCenter’s Sugarcane ( Sacchrum spp. hybrids) Breeding Program is an important step in the variety development program. The effect of nitrogen and ambient air temperature in pot cultured sugarcane were examined as a means of improving sugarcane flowering. The experiment was conducted on agronomic and reproductive traits of sugarcane at the Sugar Research Station, St. Gabriel, LA, on sugarcane genotypes subjected to artificial photoperiod regimes. The potting media consisted of equal parts of washed sand, Canadian peat moss, and a Commerce silt loam soil (fine-silty, mixed, nonacid, thermic aeric Fluvaquents). Early nitrogen (22.4-22.4-22.4 kg ha-1) …


Investigation Of Phospholipid Tubule Morphology For Use In Drug Delivery, Colleen Colson Garrett Jan 2007

Investigation Of Phospholipid Tubule Morphology For Use In Drug Delivery, Colleen Colson Garrett

LSU Doctoral Dissertations

Spherical vesicles consisting of phosphatidylcholines in which diacetylene groups have been inserted in the hydrocarbon tail centers give rise to hollow cylindrical tubes, known as “tubules”. The study of tubules has become an area of intense interest in recent years due to their unusual morphology, which raises several profound theoretical issues and suggests their use in a variety of applications. Tubule hollowness suggests medical and industrial encapsulations as well as filtration and purification applications. These potential uses, e.g., for drug and gene delivery, requires optimization of their morphology for the application. Tubules have many technologically desirable properties, such as a …


Establishment And Chemical Analysis Of Hairy Roots Of Eucommia Ulmoides, Xiaojun Wu Jan 2007

Establishment And Chemical Analysis Of Hairy Roots Of Eucommia Ulmoides, Xiaojun Wu

LSU Doctoral Dissertations

The bark of Eucommia ulmoides Oliver (Eucommiaceae) has been used over thousands of years as a folk remedy. Extracts from the bark exhibit multiple pharmacological functions, especially in lowering blood pressure. Geniposidic acid (GA), pinoresinol diglucoside (PG) and chlorogenic acid (CA) are three compounds isolated from the bark of the Eucommia tree, which display enormous bioactivities. As a type of plant tissue culture, the hairy root culture system displays prospective application over traditional cell or callus cultures, which are characterized by rapid growth, and stable biochemical and genetic capacity. The present dissertation discusses the establishment and chemical analysis of E. …


Brucella Melitensis: The Evaluation Of A Putative Hemagglutinin Gene's Effect On Virulence In The Caprine Model, Quinesha Laticia Perry Jan 2007

Brucella Melitensis: The Evaluation Of A Putative Hemagglutinin Gene's Effect On Virulence In The Caprine Model, Quinesha Laticia Perry

LSU Doctoral Dissertations

Brucella melitensis is a facultative intracellular bacterial pathogen that causes abortions in goats and sheep and Malta fever in humans. The zoonotic disease brucellosis causes severe economic losses in the Mediterranean region and parts of Africa, Asia, and Latin America. With the completion of the genomic sequences of B. abortus 2308 and B. melitensis 16M, no classical virulence factors were found; and the chromosomes were virtually identical. However, in B. melitensis, a putative hemagglutinin gene was identified which is absent in B. abortus. The possibility of the hemagglutinin gene being a potential virulence factor was evaluated via gene replacement/deletion in …


The Influence Of Values And Other Social And Psychological Factors On The Dress And Appearance Of African American College Students, Devona Linette Dixon Jan 2007

The Influence Of Values And Other Social And Psychological Factors On The Dress And Appearance Of African American College Students, Devona Linette Dixon

LSU Doctoral Dissertations

The purpose of the study was to investigate values and other social and psychological factors influence on dress and appearance of African American college students (AACS). The dependent variable was dress and appearance. Independent variables consisted of external values (being well-respected, security, warm relationships with others, and sense of belonging) and internal values (self-respect, sense of accomplishment, fun and enjoyment, self-fulfillment, and excitement). Included in the independent variables were social factors (media and referents' influence (peers and family)) and psychological factors (self-consciousness, self-confidence, fashion leadership, and shopping enjoyment). Social adaptation theory provided the theoretical framework. The theory encompasses the social …


Effects Of Cryopreservation And Constituents Of Semen Extenders On Mitochondrial Function Of Bull Spermatozoa, Abdulhakeem Hashim Eljarah Jan 2007

Effects Of Cryopreservation And Constituents Of Semen Extenders On Mitochondrial Function Of Bull Spermatozoa, Abdulhakeem Hashim Eljarah

LSU Doctoral Dissertations

This study investigated the effects of semen extender constituents and cryopreservation on bovine spermatozoal mitochondrial function. Three yearling Holstein bulls were used. Two ejaculates per bull were collected and pooled on a weekly basis for five weeks and extended in four treatments: 1) sodium citrate egg yolk extender with antibiotics (lincomycin, spectinomycin, gentamicin and tylosin); 2) ¡°1¡± with glycerol; 3) ¡°2¡± without antibiotics; and 4) ¡°1¡± without antibiotics. Each was divided into portions for analyses before freezing and after cryopreservation. The pre-freeze and thawed semen were transferred to a 37¡ãC water bath, the same assays were performed. In experiment 1, …


Probing The Association Behavior Of Hydrophobic Organic Compounds With Dissolved Humic Materials, Hadi M. Marwani Jan 2007

Probing The Association Behavior Of Hydrophobic Organic Compounds With Dissolved Humic Materials, Hadi M. Marwani

LSU Doctoral Dissertations

The association mechanism between hydrophobic organic compounds (HOC) and dissolved humic materials (DHM) has continued to be one of the interesting areas in environmental applications. The goal of the research reported in this dissertation is to investigate the association behavior of HOC with DHM. The first part of this research involves steady-state fluorescence measurements of these multi-component systems to study the effect of DHM content on the association mechanism of HOC, in particular using pyrene as a model. Results showed that steady-state fluorescence alone may not provide enough information about the quenching mechanism of pyrene with DHM. Lifetime based fluorescence …


An Investigation Of The Frictional And Thermal Behavior Of Oscillatory Sliding Line Contacts, Mongi Mansouri Jan 2007

An Investigation Of The Frictional And Thermal Behavior Of Oscillatory Sliding Line Contacts, Mongi Mansouri

LSU Doctoral Dissertations

This research deals with an experimental and numerical investigation of the frictional and thermal behavior of pin-bushing pairs, operating at reciprocating sliding motion or under heavy loads. Large interfacial temperatures developed due to frictional heating can cause failure. Therefore, numerical prediction and analysis of the surface temperature under various operating conditions are important. Laboratory tests using a pin-bushing tester provided measurements of the friction coefficient and temperature. Hard coated and plain (uncoated) bushings, both made of induction hardened stainless steel, were tested. Lower coefficient of friction and surface temperature were observed in the case of the coated bushing. In the …


Displacement And The Text: Exploring Otherness In Jean Rhys' Wide Sargasso Sea, Maryse Condé'S La Migration Des Coeurs, Rosario Ferré'S The House On The Lagoon, And Tina De Rosa's Paper Fish, Melody Boyd Carriere Jan 2007

Displacement And The Text: Exploring Otherness In Jean Rhys' Wide Sargasso Sea, Maryse Condé'S La Migration Des Coeurs, Rosario Ferré'S The House On The Lagoon, And Tina De Rosa's Paper Fish, Melody Boyd Carriere

LSU Doctoral Dissertations

This dissertation is a study of how some displaced Caribbean and Italian American women examine identity within a literary tradition that considers them "Other." I have chosen four culturally diverse novels to explore, each one written by a different female author: Jean Rhys' Wide Sargasso Sea, Maryse Condé's La migration des cœurs, Rosario Ferré's The House on the Lagoon, and Tina De Rosa's Paper Fish. I identify the causes of the protagonists' displacement, and analyze the actions they take to make themselves heard in a tradition that has formerly silenced them. The role of the mother is especially important in …


Xanthene/Benzoxanthene Dyes: Novel Synthetic Metholologies, Applications In Molecular Recognition, Cellular Imaging And The Design Of A Tunable White (Rgb) Light Emitter, Youjun Yang Jan 2007

Xanthene/Benzoxanthene Dyes: Novel Synthetic Metholologies, Applications In Molecular Recognition, Cellular Imaging And The Design Of A Tunable White (Rgb) Light Emitter, Youjun Yang

LSU Doctoral Dissertations

My graduate work has focused on the development of new fluorophore materials towards addressing several interdisciplinary research problems. Selective detection of sialic acid via a boron-amide interaction. Concentration changes of sialic acid can be monitored ratiometrically in the visible region using a boronic acid based chemosensor. The technique shows great promise for the detection of sialic acid, a critical cell surface residue involved in cancer, graft rejection and virulence in certain bacteria. There is no interference from commonly occurring oligosaccharides, aminosugars and most carboxylic acid-containing compounds. Improved synthetic methodology and studies of novel molecular probe architectures. I have developed a …


The Relationship Of Selected Personal Characteristics Of E-Faculty To Their Perceived Technological Knowledge, Myriah Christin Clark Jan 2007

The Relationship Of Selected Personal Characteristics Of E-Faculty To Their Perceived Technological Knowledge, Myriah Christin Clark

LSU Doctoral Dissertations

This study investigated the technological development of e-faculty at five randomly selected Carnegie classified (2006) Doctorate-Granting Research Universities with very high research activity (RU/VH) in the Southern Regional Education Board (SREB). The majority of e-faculty report that they do not have release time/reduced teaching load for preparing web-based materials/courses, nor do they have graduate or teaching assistants available for assisting with web-based learning. However, a little over half of them reported having instructional designers or curriculum developers to help with the designing of web-based materials and a large majority reported having adequate institutional research resources (library holdings that are accessible …


The Importance Of The Louisiana Cooperative Extension Service As Perceived By Local Governing Bodies In Louisiana, Peter Charles Cannizzaro Jan 2007

The Importance Of The Louisiana Cooperative Extension Service As Perceived By Local Governing Bodies In Louisiana, Peter Charles Cannizzaro

LSU Doctoral Dissertations

The primary purpose of this study was to determine the importance of the Louisiana Cooperative Extension Service (CES) as perceived by members of local governing bodies in Louisiana. The fundamental objective of the CES is the development of people by means of educational programs. Local governing body members (defined as Police Jury/Council Members) throughout the state of Louisiana were surveyed to determine their perceptions of the importance of the Cooperative Extension Service regarding awareness, attendance of programs/events, use of information and if the needs of local residents were being met by the LCES programs and services. Results of the study …


Improving High School Physical Science Students' Understanding Of The Electromagnetic Spectrum: A Modified Diagram Approach, James Edward Quebedeaux Jan 2007

Improving High School Physical Science Students' Understanding Of The Electromagnetic Spectrum: A Modified Diagram Approach, James Edward Quebedeaux

LSU Doctoral Dissertations

The focus of this study was to identify major conceptual difficulties that selected public high school physical science students encounter in understanding a standard electromagnetic spectrum diagram. A research-driven, modified version of that standard diagram was used in this study to determine the value added to student understanding of electromagnetic waves. A content analysis was performed on electromagnetic spectrum diagrams found in US textbooks from the 1950s through the present. A class of public high school physical science students participated in a study consisting of four activities conducted during a three-week unit. Students were given a pre- and post-achievement test …


Culture-Independent Identification Of Gut Bacteria In Fourth-Instar Red Imported Fire Ant, Solenopsis Invicta Buren, Larvae, Albert Hon-Yu Lee Jan 2007

Culture-Independent Identification Of Gut Bacteria In Fourth-Instar Red Imported Fire Ant, Solenopsis Invicta Buren, Larvae, Albert Hon-Yu Lee

LSU Doctoral Dissertations

Red imported fire ants (RIFA), Solenopsis invicta Buren, are medical, urban, and agricultural pests from South America. Fourth-instar larvae are used by the colony to digest solid food and then regurgitate it for consumption by workers and queens. Larvae are an ideal source of investigations of obligate endosymbiotic bacteria possibly involved in nutrient distributions. I attempted to first identify what bacteria species are in the guts of larvae followed by antibiotic and microscopy work to further study their roles in the ants. The composition of the bacterial community in fire ant larvae was described with culture-independent methods utilizing 16S rDNA …


Measurements And Computations Of The Flow In Full-Scale Sugar Evaporative-Crystallizers And In Lab-Scale Models, Luis Fernando Echeverri Jan 2007

Measurements And Computations Of The Flow In Full-Scale Sugar Evaporative-Crystallizers And In Lab-Scale Models, Luis Fernando Echeverri

LSU Doctoral Dissertations

The circulation of massecuite is a key factor in achieving efficient heat transfer and crystallization in sugar evaporative crystallizers, and should be as high as practically possible for recovery, quality, and capacity reasons. This research report presents results on the circulation obtained applying modern experimental and numerical techniques. The main goals are contributing to expand the understanding of the process in sugar crystallizers; developing realistic models for the simulation of the circulation; and studying the effect of different design parameters. The circulation of massecuite is driven by buoyancy force due to density difference between the vapor generated and the surrounding …


An Exploration Of The Impact Of Picture Book Illustrations On The Comprehension Skills And Vocabulary Development Of Emergent Readers, Judy Lavender Nicholas Jan 2007

An Exploration Of The Impact Of Picture Book Illustrations On The Comprehension Skills And Vocabulary Development Of Emergent Readers, Judy Lavender Nicholas

LSU Doctoral Dissertations

The formal instruction process of teaching reading to emergent and beginning readers needs to incorporate a much more multimodal approach. People today, not only in America but in many other countries as well, are more graphically oriented than any other generation has ever been. Children in our society expect to experience pictures and images in almost everything they encounter. This graphic orientation needs to be taken advantage of and incorporated into the educational process in ways that can be beneficial to the learning environments of children in our schools. Reading programs need to forego one-dimensional teaching methods and learn how …


Isolation And Characterization Of Two Closely Related Beta-Carbonic Anhydrases Of Chlamydomonas Reinhardtii, Ruby Agno Ynalvez Jan 2007

Isolation And Characterization Of Two Closely Related Beta-Carbonic Anhydrases Of Chlamydomonas Reinhardtii, Ruby Agno Ynalvez

LSU Doctoral Dissertations

Aquatic photosynthetic organisms such as the green alga, C. reinhardtii respond to low carbon dioxide conditions by inducing a carbon dioxide concentrating mechanism (CCM). Important components of the CCM are carbonic anhydrases (CAs), zinc metalloenzymes that catalyze the interconversion of carbon dioxide and bicarbonate. C. reinhardtii now has nine carbonic anhydrases, three alpha-CAs and six beta-CAs. This dissertation describes the identification and characterization of two closely related beta-CAs, CAH7 and CAH8. These CAs are 63% identical. CAH7 and CAH8 encode proteins of 399 and 333 amino acids, respectively. Both of these CAs are constitutively expressed at the transcript and protein …


An Investigation Of Maternal Psychopathology As A Moderator Of Child Response Following Hurricane Katrina, Ann Wingate Spell Jan 2007

An Investigation Of Maternal Psychopathology As A Moderator Of Child Response Following Hurricane Katrina, Ann Wingate Spell

LSU Doctoral Dissertations

Previous disaster research has focused on possible risk factors that contribute to child psychological distress following disaster exposure. One of these factors, parental psychopathology, has consistently been indicated as associated with and predictive of child functioning post-disaster. In related areas of violence exposure, researchers have gone beyond correlation and prediction in their attempt to elucidate the relationship between parental psychopathology and child functioning post-trauma. Such researchers have investigated and confirmed parental psychopathology as a moderator variable in the relationship between child violence exposure and child functioning. Thus, in considering the status of research regarding risk factors of child functioning post-disaster …


Application-Specific Reliable Data Transfer In Wireless Sensor Networks, Damayanti Datta Jan 2007

Application-Specific Reliable Data Transfer In Wireless Sensor Networks, Damayanti Datta

LSU Doctoral Dissertations

A wireless sensor network (WSN) is a collection of sensor nodes and base stations connected via wireless medium. It sends data collected from the nodes to the base stations for generating information. The size and low cost of the sensor nodes as well as the WSN's ability to connect without wired links are its key advantages which enable it to be deployed in hostile or inaccessible environments at low cost. However, WSNs suffer from high data loss due to the inherent weaknesses in a wireless transmission medium, transmission problems in hostile environments due to human interference, etc. and node failures …


Local Norms And Innovations Within The System Of Locative Prepositions In Cajun French, Sibylle Maria Noetzel Jan 2007

Local Norms And Innovations Within The System Of Locative Prepositions In Cajun French, Sibylle Maria Noetzel

LSU Doctoral Dissertations

Cajun French presents variable use of linguistic features, as any other variety of French does. Many Cajun French features are considered as deviant from the French norm or triggered by attrition although fluent speakers of Cajun French have always used them. In this sociolinguistic study, we analyze the use of locative prepositions. We add two important dimensions to existing studies: real-time evidence for a diachronic descriptive perspective, and a methodological tool, measuring the degree of exposure to French (MDI). This approach allows us to establish the local prepositional norm of Cajun French and phenomena due to attrition. Large amounts of …


Effects Of Capping On Biodegradation Of Organic Contaminants In Sediments, Eun Ju Lee Jan 2007

Effects Of Capping On Biodegradation Of Organic Contaminants In Sediments, Eun Ju Lee

LSU Doctoral Dissertations

Sediment capping remains an effective remediation technique for contaminated sediments due to its capability to contain contaminants and provide a sound habitat for indigenous biota. This research investigated the effect of capping on biodegradation of organic contaminants in Anacostia River sediments using both experimental and modeling techniques. 14C–Phenanthrene mineralization was monitored under various redox conditions in Anacostia River sediments. Mineralization of 14C–phenanthrene was strongly linked to sulfate reduction, which was the more energetic process than any other anaerobic condition in Anacostia sediments. Sulfate is a more promising terminal electron acceptor for intrinsic degradation in Anacostia River and other PAH contaminated …


P-Glycoprotein And Membrane Permeability As Determinants Of Xenobiotic Bioavailability And Bioaccumulation, Xiaobing Tan Jan 2007

P-Glycoprotein And Membrane Permeability As Determinants Of Xenobiotic Bioavailability And Bioaccumulation, Xiaobing Tan

LSU Doctoral Dissertations

The ABC transporter P-glycoprotein (Pgp) and membrane permeability are determinant factors for absorption and disposition of xenobiotics. These studies investigated the effects of potential modulators of Pgp and/or membrane function on the disposition, bioavailability and bioaccumulation of environmentally relevant pharmaceuticals, tetracycline and ivermectin, and the carcinogen benzo[a]pyrene in catfish. The pesticide dieldrin and surfactant linear alkylbenzene sulfonate (LAS) were selected as mixture components thought to have potential interactions with these determinants of disposition. Initial in situ experiments demonstrated dieldrin and tetracycline both significantly inhibited biliary excretion of Pgp prototypic substrate Rhodamine-123 in isolated perfused livers. Further, dieldrin (20µM) reduced movement …


Electrodeposition Of Multilayered Nanostructures For Giant Magnetoresistance And Thermoelectric Applications, Despina Davis Jan 2007

Electrodeposition Of Multilayered Nanostructures For Giant Magnetoresistance And Thermoelectric Applications, Despina Davis

LSU Doctoral Dissertations

The electrodeposition of novel materials such as multilayer nanotubes for giant magneto resistance (GMR) applications and bismuth telluride nanotubes for thermoelectric applications are presented in this dissertation. The motivation for the multilayer electrodeposition is the investigation of giant magnetoresistance (GMR), a change in the material resistance in an applied magnetic field as a consequence of antiferromagnetic coupling. The nanowire high aspect ratio geometry allows the measurement of GMR with the current applied perpendicular to the plane (CPP) of the multilayers, which has been theoretically identified as being larger than the GMR in the (CIP) configuration (current in plane of multilayers). …