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Articles 61 - 90 of 100
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Physical Stability Of Poly (Lactic-Co-Glycolic Acid) And Plga/Chitosan Nanoparticles And Chemical Stability Of Entrapped Alpha-Tocopherol And Lutein, Meocha Whaley
LSU Master's Theses
The published benefits of polymeric nanoparticles as a system for antioxidant delivery have encompassed topics of improved oral delivery, bioavailability, and modified release to name a few. Generally accepted as safe polymers Poly(lactic-coglycolic acid) and the mucoadhesive chitosan were selected to entrap alpha-tocopherol and lutein. This study proposed to assess the physical stability of PLGA and Chi/PLGA nanoparticles with entrapped bioactives in varying biological suspension medias ( water, pbs, hbss and cell media). Also, to assess the chemical stability of the entrapped antioxidants lutein and alpha-tocopherol within the same media as deemed relevant for in-vitro and and in-vivo studies. Of …
Analyzing The Population Structure Of Captive Marmosets Using Alu Retrotransposons, Megan Ranck
Analyzing The Population Structure Of Captive Marmosets Using Alu Retrotransposons, Megan Ranck
Honors Capstones
No abstract provided.
Exploring Post-Translational Arginine Modification Using Chemically Synthesized Methylglyoxal Hydroimidazolones, Tina Wang, Rendy Kartika, David A. Spiegel
Exploring Post-Translational Arginine Modification Using Chemically Synthesized Methylglyoxal Hydroimidazolones, Tina Wang, Rendy Kartika, David A. Spiegel
Faculty Publications
The methylglyoxal-derived hydroimidazolones (MG-Hs) comprise the most prevalent class of non-enzymatic, post-translational modifications of protein arginine residues found in nature. These adducts form spontaneously in the human body, and are also present at high levels in the human diet. Despite numerous lines of evidence suggesting that MG-H-arginine adducts play critical roles in both healthy and disease physiology in humans, detailed studies of these molecules have been hindered by a lack of general synthetic strategies for their preparation in chemically homogeneous form, and on scales sufficient to enable detailed biochemical and cellular investigations. To address this limitation, we have developed efficient, …
Single-Molecule Detection Of Molecular Beacons Generated From Ldr On Thermoplastic Microfluidic Device For Bioanalysis, Zhiyong Peng
Single-Molecule Detection Of Molecular Beacons Generated From Ldr On Thermoplastic Microfluidic Device For Bioanalysis, Zhiyong Peng
LSU Doctoral Dissertations
Current clinical techniques for nucleic acid detection and analysis often involve PCR, lacking adequate specificity or sensitivity to meet the stringent requirements in certain applications. This research aims to develop an innovative molecular assay and the associated hardware to rapidly signal the presence of certain targets using reporter sequence found in their genome without requiring PCR. This assay coupled the sensitivity of single-pair fluorescence resonance energy transfer (spFRET) with the specificity of ligase detection reaction (LDR) to provide near real-time readout of target biomarkers. Heightened concerns on potential bioterrorism threats, such as rapid dissemination of pathogenic bacteria or viruses into …
Pharmacokinetic Pilot Study Of The Antiangiogenic Activity Of Standardized Platycodi Radix, Emma M. Twiner, Zhijun Liu, Jeffrey Gimble, Ying Yu, Frank Greenway
Pharmacokinetic Pilot Study Of The Antiangiogenic Activity Of Standardized Platycodi Radix, Emma M. Twiner, Zhijun Liu, Jeffrey Gimble, Ying Yu, Frank Greenway
Faculty Publications
Introduction: Platycodi radix is a radish used in food, such as Korean kimchi, and has been shown to cause weight loss in rodents. Platycodin D is considered its active ingredient and has been shown to inhibit lipases. The authors hypothesized that platycodi radix and the platycodin D it contains inhibit angiogenesis; another mechanism for weight loss. Methods: This study tested platycodi radix extract, platycodin D, and an extract of platycodi radix standardized to platycodin D for their ability to inhibit angiogenesis in a human adipose tissue assay. This study treated five healthy volunteers, orally, with platycodi radix extract standardized to …
The Nlrp3 Inflammasome Instigates Obesity-Induced Inflammation And Insulin Resistance, Bolormaa Vandanmagsar, Yun Hee Youm, Anthony Ravussin, Jose E. Galgani, Krisztian Stadler, Randall L. Mynatt, Eric Ravussin, Jacqueline M. Stephens, Vishwa Deep Dixit
The Nlrp3 Inflammasome Instigates Obesity-Induced Inflammation And Insulin Resistance, Bolormaa Vandanmagsar, Yun Hee Youm, Anthony Ravussin, Jose E. Galgani, Krisztian Stadler, Randall L. Mynatt, Eric Ravussin, Jacqueline M. Stephens, Vishwa Deep Dixit
Faculty Publications
The emergence of chronic inflammation during obesity in the absence of overt infection or well-defined autoimmune processes is a puzzling phenomenon. The Nod-like receptor (NLR) family of innate immune cell sensors, such as the nucleotide-binding domain, leucine-rich-containing family, pyrin domain-containing-3 (Nlrp3, but also known as Nalp3 or cryopyrin) inflammasome are implicated in recognizing certain nonmicrobial originated 'danger signals' leading to caspase-1 activation and subsequent interleukin-1β 2 (IL-1β 2) and IL-18 secretion. We show that calorie restriction and exercise-mediated weight loss in obese individuals with type 2 diabetes is associated with a reduction in adipose tissue expression of Nlrp3 as well …
Developing A Tool To Characterize The Ultradian Rhythm In Diploid Saccharomyces Cervisiae Using The Reporter Gene Green Fluorescent Protein, Imran Chiragh
LSU Master's Theses
Biological rhythms control many temporal behaviors of organism, such as the sleep cycle, hearts rhythms, seasonal animal migrations etc. Understanding these rhythms would provide insight into the temporal process of living organisms. Saccharomyces cerevisiae, a budding yeast, is an ideal model organism to study biological rhythms in eukaryotic cells because of its sequenced genome and discerned processes. By characterizing the biological rhythm in budding yeast, insight can be gained into more complex organisms. Previous studies have exhibited oscillatory behavior of oxygen consumption and determined that deletion of the GTS1 gene dissipates this rhythm. However, to further understand the specific behavior …
The Effects Of Reiki Treatment On Mental Health Professionals Who Are At Risk For Secondary Traumatic Stress, Martha P. Novoa
The Effects Of Reiki Treatment On Mental Health Professionals Who Are At Risk For Secondary Traumatic Stress, Martha P. Novoa
LSU Doctoral Dissertations
The purpose of this cross-sectional experimental study was to examine the effects of Reiki on risk level for secondary traumatic stress (STS) among mental health professionals, such as, social workers and licensed professional counselor (LPCs). The sample (N=67) was mostly composed of master social work students (MSW) (61%) from the School of Social Work at Louisiana State University (LSU), professionals social workers (34%), and LPCs (5%). Study participants were randomly assigned to one of three treatment groups: Reiki, placebo or control group. Dependent variables measured at pretest and posttest were: risk level for STS, anxiety, depression, somatic symptoms, anger and …
Structural And Functional Insights Of Human 5-Lipoxygenase, Nathaniel Carson Gilbert
Structural And Functional Insights Of Human 5-Lipoxygenase, Nathaniel Carson Gilbert
LSU Doctoral Dissertations
This work describes the structure of human 5-lipoxygenase (5-LOX) (Gilbert, Bartlett et al. 2011) and the techniques required to ascertain the structure. 5-LOX is a notoriously unstable enzyme with important biological functions. The human 5-LOX has been implicated in many disease states including asthma, atherosclerosis and cancer. Part of 5-LOX biology is the inherent instability of the enzyme, which is thought to help regulate the production of its pro-inflammatory products, the leukotrienes. Our objective was stabilizing the enzyme for in vitro studies without affecting catalytic fidelity. I was able to quantitate stabilizing and destabilizing point mutations of 5-LOX by thermal …
Retention Of Students In A Diploma Nursing Program In The Southern United States, Carol Ann Tingle
Retention Of Students In A Diploma Nursing Program In The Southern United States, Carol Ann Tingle
LSU Doctoral Dissertations
Registered Nurses comprise the largest group of healthcare professionals in the United States, and forecasts predict a nursing shortage of epic proportions on the horizon. Significant factors include approaching retirement of Baby Boomer RNs, increased demand for care for aging Baby Boomers in the population, approaching retirement of nurse educators, and rejection of qualified applicants secondary to enrollment restrictions in nursing programs. Nursing student attrition further contributes to the pending shortage. Successful retention programs promote best-practice utilization of scarce resources. Understanding student characteristics serves as a basis for effective selection and retention programs. This study described characteristics of nursing students …
Fabrication Of Receptor-Modified Microfluidic Surfaces For Applications In Glycoprotein Screening, Jennifer Macalindong De Guzman
Fabrication Of Receptor-Modified Microfluidic Surfaces For Applications In Glycoprotein Screening, Jennifer Macalindong De Guzman
LSU Doctoral Dissertations
Glycoproteins have long been identified to have a profound association with human pathological processes, and they are much sought after as potential biomarkers to aid in the early diagnosis and clinical prognosis of cancers and diseases. There is currently high demand for high-throughput and low–limit–of–detection techniques that can afford profiling of the glycoproteome. Micro-total analysis systems (µTAS) based on microfluidics have the potential to fulfill these requirements, but in order to reduce the complexity of the protein pool, the µTAS devices must contain a pre-isolation and enrichment component. The research project undertaken here involved derivatization of microfluidic …
Breaking The Spell: Developing A New Generation Of Porphyrins For Treating Cerebral Tumors, Ryan Harrison Gray
Breaking The Spell: Developing A New Generation Of Porphyrins For Treating Cerebral Tumors, Ryan Harrison Gray
Honors Capstones
No abstract provided.
Genome Analysis Of The Platypus Reveals Unique Signatures Of Evolution, Wesley C. Warren, La Deana W. Hillier, Jennifer A. Marshall Graves, Ewan Birney, Chris P. Ponting, Frank Grützner, Katherine Belov, Webb Miller, Laura Clarke, Asif T. Chinwalla, Shiaw Pyng Yang, Andreas Heger, Devin P. Locke, Pat Miethke, Paul D. Waters, Frédéric Veyrunes, Lucinda Fulton, Bob Fulton, Tina Graves, John Wallis, Xose S. Puente, Carlos López-Otín, Gonzalo R. Ordóñez, Evan E. Eichler, Lin Chen, Ze Cheng, Janine E. Deakin, Amber Alsop, Katherine Thompson, Patrick Kirby, Anthony T. Papenfuss, Matthew J. Wakefield, Tsviya Olender, Doron Lancet
Genome Analysis Of The Platypus Reveals Unique Signatures Of Evolution, Wesley C. Warren, La Deana W. Hillier, Jennifer A. Marshall Graves, Ewan Birney, Chris P. Ponting, Frank Grützner, Katherine Belov, Webb Miller, Laura Clarke, Asif T. Chinwalla, Shiaw Pyng Yang, Andreas Heger, Devin P. Locke, Pat Miethke, Paul D. Waters, Frédéric Veyrunes, Lucinda Fulton, Bob Fulton, Tina Graves, John Wallis, Xose S. Puente, Carlos López-Otín, Gonzalo R. Ordóñez, Evan E. Eichler, Lin Chen, Ze Cheng, Janine E. Deakin, Amber Alsop, Katherine Thompson, Patrick Kirby, Anthony T. Papenfuss, Matthew J. Wakefield, Tsviya Olender, Doron Lancet
Faculty Publications
We present a draft genome sequence of the platypus, Ornithorhynchus anatinus. This monotreme exhibits a fascinating combination of reptilian and mammalian characters. For example, platypuses have a coat of fur adapted to an aquatic lifestyle; platypus females lactate, yet lay eggs; and males are equipped with venom similar to that of reptiles. Analysis of the first monotreme genome aligned these features with genetic innovations. We find that reptile and platypus venom proteins have been co-opted independently from the same gene families; milk protein genes are conserved despite platypuses laying eggs; and immune gene family expansions are directly related to platypus …
The Use Endocrine Markers To Predict And Monitor Performance In Strengh [Sic] And Power Activities, Jason B. Winchester
The Use Endocrine Markers To Predict And Monitor Performance In Strengh [Sic] And Power Activities, Jason B. Winchester
LSU Doctoral Dissertations
Hormones are typically considered to be chemical messengers, which are designed to be released from specific cells where they are carried to their target tissues for binding to receptors. It is this binding of a hormone molecule to its specific receptor which allows for an action to occur (Hadley and Levine 2006). Testosterone is the predominant androgen in the majority of mammalian species and is largely responsible for regulation of reproduction and maintenance of sexual function. In addition, in adult mammals, T has multiple other roles including the growth of muscle and bone, hematopoesis, blood coagulation, development and regulation of …
Iron And Zinc Physiology In Sweetpotato, Mary Catherine Singleton
Iron And Zinc Physiology In Sweetpotato, Mary Catherine Singleton
LSU Master's Theses
Sweetpotato [Ipomoea batatas (L.) Lam.] is an important provider of nutrition in developing countries. High productivity in the form of starch and beta carotene richness underlies its potential. A sweetpotato with adequate levels of iron and zinc would greatly aid efforts to reduce dietary deficiencies of iron and zinc. The objective of this work is to document the physiological accumulation of iron and zinc in sweetpotato during development and the mechanisms responsible for iron uptake. Six varieties (‘IPS 163, ‘Beauregard’,‘Koto-puki’, ‘Pung-mi’, ‘Duanyanghon’, and ‘Xushu 18’) were compared to understand iron and zinc accumulation during development. Results showed that micronutrient content …
Numerical Simulations Of Flow And Mass Transport In Micro-Fluidic Components For Modular Bio-Analytic Chip Applications, Sudheer D. Rani
Numerical Simulations Of Flow And Mass Transport In Micro-Fluidic Components For Modular Bio-Analytic Chip Applications, Sudheer D. Rani
LSU Doctoral Dissertations
Microfluidics has received a great deal of attention in the past decade. The ability of modular microfluidic chips to miniaturize integrate chemical and biological systems (µTAS) can be greatly productive in terms of cost and efficiency. During the design of these modular devices, misalignment of materials, geometrical or both is one of the most common problems. These misalignments can have adverse effect in both pressure driven and electrokinetically driven flows. In the present work, Numerical Simulations have been performed to study the effect of material and geometrical mismatch on the flow behavior and species progression in microfluidic interconnects. In the …
Mobile Dna In Old World Monkeys: A Glimpse Through The Rhesus Macaque Genome, Kyudong Han, Miriam K. Konkel, Jinchuan Xing, Hui Wang, Jungnam Lee, Thomas J. Meyer, Charles T. Huang, Erin Sandifer, Kristi Hebert, Erin W. Barnes, Robert Hubley, Webb Miller, Arian F.A. Smit, Brygg Ullmer, Mark A. Batzer
Mobile Dna In Old World Monkeys: A Glimpse Through The Rhesus Macaque Genome, Kyudong Han, Miriam K. Konkel, Jinchuan Xing, Hui Wang, Jungnam Lee, Thomas J. Meyer, Charles T. Huang, Erin Sandifer, Kristi Hebert, Erin W. Barnes, Robert Hubley, Webb Miller, Arian F.A. Smit, Brygg Ullmer, Mark A. Batzer
Faculty Publications
The completion of the draft sequence of the rhesus macaque genome allowed us to study the genomic composition and evolution of transposable elements in this representative of the Old World monkey lineage, a group of diverse primates closely related to humans. The L1 family of long interspersed elements appears to have evolved as a single lineage, and Alu elements have evolved into four currently active lineages. We also found evidence of elevated horizontal transmissions of retroviruses and the absence of DNA transposon activity in the Old World monkey lineage. In addition, ∼100 precursors of composite SVA (short interspersed element, variable …
Evolutionary And Biomedical Insights From The Rhesus Macaque Genome, Richard A. Gibbs, Jeffrey Rogers, Michael G. Katze, Roger Bumgarner, George M. Weinstock, Elaine R. Mardis, Karin A. Remington, Robert L. Strausberg, J. Craig Venter, Richard K. Wilson, Mark A. Batzer, Carlos D. Bustamante, Evan E. Eichler, Matthew W. Hahn, Ross C. Hardison, Kateryna D. Makova, Webb Miller, Aleksandar Milosavljevic, Robert E. Palermo, Adam Siepel, James M. Sikela, Tony Attaway, Stephanie Bell, Kelly E. Bernard, Christian J. Buhay, Mimi N. Chandrabose, Marvin Dao, Clay Davis, Kimberly D. Delehaunty, Yan Ding, Huyen H. Dinh, Shannon Dugan-Rocha, Lucinda A. Fulton, Ramatu Ayiesha Gabisi
Evolutionary And Biomedical Insights From The Rhesus Macaque Genome, Richard A. Gibbs, Jeffrey Rogers, Michael G. Katze, Roger Bumgarner, George M. Weinstock, Elaine R. Mardis, Karin A. Remington, Robert L. Strausberg, J. Craig Venter, Richard K. Wilson, Mark A. Batzer, Carlos D. Bustamante, Evan E. Eichler, Matthew W. Hahn, Ross C. Hardison, Kateryna D. Makova, Webb Miller, Aleksandar Milosavljevic, Robert E. Palermo, Adam Siepel, James M. Sikela, Tony Attaway, Stephanie Bell, Kelly E. Bernard, Christian J. Buhay, Mimi N. Chandrabose, Marvin Dao, Clay Davis, Kimberly D. Delehaunty, Yan Ding, Huyen H. Dinh, Shannon Dugan-Rocha, Lucinda A. Fulton, Ramatu Ayiesha Gabisi
Faculty Publications
The rhesus macaque (Macaca mulatta) is an abundant primate species that diverged from the ancestors of Homo sapiens about 25 million years ago. Because they are genetically and physiologically similar to humans, rhesus monkeys are the most widely used nonhuman primate in basic and applied biomedical research. We determined the genome sequence of an Indian-origin Macaca mulatta female and compared the data with chimpanzees and humans to reveal the structure of ancestral primate genomes and to identify evidence for positive selection and lineage-specific expansions and contractions of gene families. A comparison of sequences from individual animals was used to investigate …
Generation And Characterization Of Rabbit Embryonic Stem Cells, Shufen Wang, Xianghui Tang, Yuyu Niu, Hongwei Chen, Bin Li, Tianqing Li, Xiuzhen Zhang, Zhixin Hu, Qi Zhou, Weizhi Ji
Generation And Characterization Of Rabbit Embryonic Stem Cells, Shufen Wang, Xianghui Tang, Yuyu Niu, Hongwei Chen, Bin Li, Tianqing Li, Xiuzhen Zhang, Zhixin Hu, Qi Zhou, Weizhi Ji
Faculty Publications
We described the derivation of four stable pluripotent rabbit embryonic stem cell (ESC) lines, one (RF) from blastocysts fertilized in vivo and cultured in vitro and three (RP01, RP02, and RP03) from parthenogenetic blastocysts. These ESC lines have been cultivated for extended periods (RF >1 year, RP01 >8 months, RP02 >8 months, and RP03 >6 months) in vitro while maintaining expression of pluripotent ESC markers and a normal XY or XX karyotype. The ESCs from all lines expressed alkaline phosphatase, transcription factor Oct-4, stage-specific embryonic antigens (SSEA-1, SSEA-3, and SSEA-4), and the tumor-related antigens (TRA-1-60 and TRA-1-81). Similar to human …
"Aaron's Serpent": The Ideology Of The "Master Passion" In English Serious Drama, 1660-1880, William J. Burling
"Aaron's Serpent": The Ideology Of The "Master Passion" In English Serious Drama, 1660-1880, William J. Burling
1650-1850: Ideas, Aesthetics, and Inquiries in the Early Modern Era
No abstract provided.
The Use Of A Chiral Fluorescent Resorcinarene For The Enantiomeric Recognition Of Amino Acids, Gerald I. Richard
The Use Of A Chiral Fluorescent Resorcinarene For The Enantiomeric Recognition Of Amino Acids, Gerald I. Richard
LSU Master's Theses
The spectroscopic properties of a chiral boronic acid based resorcinarene macrocycle employed for chiral analysis were investigated. Specifically, the emission and excitation characteristics of tetraarylboronate resorcinarene macrocycle (TBRM) and its quantum yield were evaluated. The chiral selector TBRM was investigated as a chiral reagent for the enantiomeric discrimination of amino acids using steady-state fluorescence spectroscopy. Chiral recognition of amino acids in the presence of the macrocycle was based on diastereomeric complexes. Results demonstrated that TBRM had better chiral discrimination ability for lysine as compared to the other amino acids. Partial-least-squares regression modeling (PLS-1) of spectral data for macrocycle-lysine host-guest complexes …
Genotypic Variability And Inheritance Of Iron And Zinc In Sweetpotato, Michael William Courtney
Genotypic Variability And Inheritance Of Iron And Zinc In Sweetpotato, Michael William Courtney
LSU Master's Theses
Sweetpotato [Ipomœa batatas (L.) Lam.] is a major subsistence crop in Sub-Saharan Africa, where iron and zinc deficiency in humans is an important health problem. A sweetpotato cultivar suited for subsistence farming, with high iron and zinc concentration, would be important in alleviating these deficiencies. The main objective of this research was to identify the extent of genetic variability of iron and zinc concentration in sweetpotato germplasm. An important subcomponent of this research was to determine the heritability of iron and zinc in sweetpotato. Protocol development studies were also conducted to aid in determining proper sampling technique. The results of …
A Chemomechanical Polymer That Functions In Blood Plasma With High Glucose Selectivity, George K. Samoei, Weihua Wang, Jorge O. Escobedo, Xiangyang Xu, Hans Jörg Schneider, Robert L. Cook, Robert M. Strongin
A Chemomechanical Polymer That Functions In Blood Plasma With High Glucose Selectivity, George K. Samoei, Weihua Wang, Jorge O. Escobedo, Xiangyang Xu, Hans Jörg Schneider, Robert L. Cook, Robert M. Strongin
Faculty Publications
(Figure Presented) See the shrink: Systematic modification of poly(methyl methacrylate) leads to a chemomechanical polymer that selectively contracts in the presence of glucose at physiological levels in human blood plasma. The polymer also exhibits good reversibility allowing continuous expansion-contraction cycles. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.
From The Top Down And The Bottom Up: The Contemporary Practice And Choice Of Midwifery In Louisiana, Michelle M. Wydra
From The Top Down And The Bottom Up: The Contemporary Practice And Choice Of Midwifery In Louisiana, Michelle M. Wydra
LSU Master's Theses
This research examines the contemporary practice of midwifery in Louisiana, a state that very early on had progressive legislation, yet remains a tough place for a midwife to practice. What, then, are the social forces that affect the ability to practice midwifery in Louisiana? I try to answer that question by examining the narratives of midwives and their clients, and evaluating the options these women have access to in this state. The narratives provide opportunities to observe the authoritarian knowledge of biomedicine in our society, and apply Foucault’s theory of power/knowledge. I describe that although Louisiana’s regulation of the practice …
Energy Aware Topology Control Protocols For Wireless Sensor Networks, Shilpa Dhar
Energy Aware Topology Control Protocols For Wireless Sensor Networks, Shilpa Dhar
LSU Master's Theses
Wireless Sensor Network has emerged as an important technology of the future due to its potential for application across a wide array of domains. The collaborative power of numerous autonomousremote sensing nodes self configured into a multi hop network permits in-depth accurate observation of any physical phenomenon. A stringent set of computational and resource constraints make the design and implementation of sensor networks an arduous task. The issue of optimizing the limited and often non-renewable energy of sensor nodes due to its direct impact on network lifetime dominates every aspect of wireless sensor networks. Existing techniques for optimizing energy consumption …
State-Specific Effects Of Withdrawal In Smokers, Carla J. Rash
State-Specific Effects Of Withdrawal In Smokers, Carla J. Rash
LSU Master's Theses
Comparisons of responses to a free-recall task were made in withdrawal and non-withdrawal states of 41 smokers. A 2 x 2 design was used to investigate state-specific learning effects in smokers during nicotine withdrawal using a list of 20 common words. Nicotine withdrawal was defined as a minimum of 12 hours abstinence from smoking. Physiological measures of heart rate and blood pressure were examined for drug-compensatory responses. No significant decreases in physiological responding were found. Additionally, no interaction was found between reported urge and withdrawal. The primary hypothesis regarding state-specific effects on recall was not supported. These findings are to …
An Analysis Of Cardiovascular And Respiratory Mortality As A Function Of Ambient Ozone And Fine Particulate Matter In The Baton Rouge Air Quality Control Region, Thomas James Wiley Iv
An Analysis Of Cardiovascular And Respiratory Mortality As A Function Of Ambient Ozone And Fine Particulate Matter In The Baton Rouge Air Quality Control Region, Thomas James Wiley Iv
LSU Master's Theses
The Baton Rouge Air Quality Control Region has come under fire due to difficulties in reaching attainment of one-hour daily ozone limitations and its general perception as being a polluted place to live. Ozone is a reactive oxygen species which has been shown to result in damage to biological molecules and is detrimental to human physiology, especially in regards to cardio-respiratory structure and function. In the last decade, fine particulate matter less than 2.5 microns in mean aerodynamic diameter have been identified as a possible pollutant that is affecting public health at levels lower than the EPA’s established limits. PM2.5 …
19th And 20th Century French Exoticism: Pierre Loti, Louis-Ferdinand Cé́Line, Michel Leiris, And Simone Schwarz-Bart, Robin Anita White
19th And 20th Century French Exoticism: Pierre Loti, Louis-Ferdinand Cé́Line, Michel Leiris, And Simone Schwarz-Bart, Robin Anita White
LSU Doctoral Dissertations
This study of four 19th and 20th century colonial texts, as well as a later postcolonial novel exposes the cadres exotiques, or exotic frameworks, of literary exoticism. The thesis names and interprets the moods of and reactions to exoticism, including colonial exoticism, antiexoticism, and autoexoticism. Poetic and theoretical interpretations of exoticism, such as Victor Segalen’s Notion du Divers and Edouard Glissant’s Opacité and Poétique de la Relation challenge the prevalent assumptions that the literary practice was only an unfortunate byproduct of colonialism. The first chapter presents literary history and theoretical considerations relating to exoticism: Orientalism, nostalgia, colonial literary history, and …
A Meta-Analysis Of Genome-Wide Linkage Scans For Hypertension: The National Heart, Lung And Blood Institute Family Blood Pressure Program, Michael A. Province, Sharon L.R. Kardia, Koustubh Ranade, Dabeeru C. Rao, Bonnie A. Thiel, Richard S. Cooper, Neil Risch, Stephen T. Turner, David R. Cox, Steven C. Hunt, Alan B. Weder, Eric Boerwinkle
A Meta-Analysis Of Genome-Wide Linkage Scans For Hypertension: The National Heart, Lung And Blood Institute Family Blood Pressure Program, Michael A. Province, Sharon L.R. Kardia, Koustubh Ranade, Dabeeru C. Rao, Bonnie A. Thiel, Richard S. Cooper, Neil Risch, Stephen T. Turner, David R. Cox, Steven C. Hunt, Alan B. Weder, Eric Boerwinkle
Faculty Publications
Background: Four multicenter Networks (GenNet, GENOA, HyperGEN, SAPPHIRe) form the National Heart, Lung and Blood Institute Family Blood Pressure Program (FBPP), to search for hypertension/blood pressure (BP) genes. The networks used different family designs and targeted multiple ethnic groups, using standardized protocols and definitions. Linkage genome scans were done on samples within each network (N = 6245 relatives). Methods: The evidence was synthesized using meta-analysis. Results: Combining ethnic groups, no region reached LOD >2, but several small peaks were identified, including chromosome 2p where two other recent reports find hypertension linkage. Conclusions: No regions show uniformly large effects on BP/hypertension …
The Effects Of Singing On Blood Pressure In Classically Trained Singers, Kimberly Jaye Broadwater
The Effects Of Singing On Blood Pressure In Classically Trained Singers, Kimberly Jaye Broadwater
LSU Major Papers
Blood pressure readings were taken in four normotensive, classically trained singers of varying age and experience. The results show changes during the systolic and diastolic phases of blood pressure measurements while singing. While systolic blood pressure changes were individualized and random, diastolic blood pressure changes generally showed a direct correlation to changes in intrathoracic pressure. Additional research using a larger subject base involving normotensive, hypertensive, and hypotensive populations is warranted.