Digital Commons Network^™

Intramuscular Vaccination Of Mice With The Human Herpes Simplex Virus Type-1(Hsv-1) Vc2 Vaccine, But Not Its Parental Strain Hsv-1 (F) Confers Full Protection Against Lethal Ocular Hsv-1 (Mckrae) Pathogenesis, Shan K. Naidu, Rafiq Nabi, Nagarjuna R. Cheemarla, Brent A. Stanfield, Paul J. Rider, Nithya Jambunathan, Vladimir N. Chouljenko, Renee Carter, Fabio Del Piero, Ingeborg Langohr, Konstantin G. Kousoulas

Faculty Publications

Copyright: © 2020 Naidu et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Herpes simplex virus type-1 (HSV-1) can cause severe ocular infection and blindness. We have previously shown that the HSV-1 VC2 vaccine strain is protective in mice and guinea pigs against genital herpes infection following vaginal challenge with HSV-1 or HSV-2. In this study, we evaluated the efficacy of VC2 intramuscular vaccination in mice against herpetic keratitis following ocular challenge with …

Sleep Characteristics And Health-Related Quality Of Life In 9- To 11-Year-Old Children From 12 Countries, Qian Xiao, Jean Philippe Chaput, Timothy Olds, Mikael Fogelholm, Gang Hu, Estelle V. Lambert, Carol Maher, Jose Maia, Vincent Onywera, Olga L. Sarmiento, Martyn Standage, Mark S. Tremblay, Catrine Tudor-Locke, Peter T. Katzmarzyk

Population and Public Health Science Faculty Publications

Introduction: Previous studies have linked short sleep duration, poor sleep quality, and late sleep timing with lower health-related quality of life (HRQoL) in children. However, almost all studies relied solely on self-reported sleep information, and most studies were conducted in high-income countries. To address these gaps, we studied both device-measured and self-reported sleep characteristics in relation to HRQoL in a sample of children from 12 countries that vary widely in terms of economic and human development. Methods: The study sample included 6,626 children aged 9-11 years from Australia, Brazil, Canada, China, Colombia, Finland, India, Kenya, Portugal, South Africa, the United …

Optimal Uniform Continuity Bound For Conditional Entropy Of Classical–Quantum States, Mark M. Wilde

Faculty Publications

In this short note, I show how a recent result of Alhejji and Smith (A tight uniform continuity bound for equivocation, 2019. arXiv:1909.00787v1) regarding an optimal uniform continuity bound for classical conditional entropy leads to an optimal uniform continuity bound for quantum conditional entropy of classical–quantum states. The bound is optimal in the sense that there always exists a pair of classical–quantum states saturating the bound, and so, no further improvements are possible. An immediate application is a uniform continuity bound for the entanglement of formation that improves upon the one previously given by Winter (Commun Math Phys 347(1):291–313, 2016. …

Β-Delayed Neutron Emission Studies Of I 137,138 And Cs 144,145 Performed With Trapped Ions, A. Czeszumska, N. D. Scielzo, S. A. Caldwell, J. A. Clark, G. Savard, B. S. Wang, A. Aprahamian, M. T. Burkey, C. J. Chiara, J. Harker, A. F. Levand, S. T. Marley, G. Morgan, J. M. Munson, E. B. Norman, A. Nystrom, R. Orford, S. W. Padgett, A. Pérez Galván, K. S. Sharma, K. Siegl, S. Y. Strauss

Faculty Publications

A detailed study of the β-delayed neutron emission properties of I137,138 and Cs144,145 has been performed by confining ions in the Beta-decay Paul Trap. The daughter ions following β decay emerge from the trapped-ion cloud with negligible scattering allowing reconstruction of the recoil-ion energy from the time of flight. From this information, the neutron-emission branching ratios and neutron-energy spectra were deduced. The results for the I137 and Cs144,145 decays are in agreement with previous results performed using direct neutron-detection techniques. In the case of I138, a branching ratio of 6.18(50)% is obtained, yielding a value consistent with the more recent …

Β-Delayed-Neutron Studies Of Sb 135,136 And I 140 Performed With Trapped Ions, B. S. Wang, S. A. Caldwell, N. D. Scielzo, A. Czeszumska, J. A. Clark, G. Savard, A. Aprahamian, M. T. Burkey, C. J. Chiara, J. Harker, A. F. Levand, S. T. Marley, G. E. Morgan, J. M. Munson, E. B. Norman, A. Nystrom, R. Orford, S. W. Padgett, A. Pérez Galván, K. S. Sharma, K. Siegl, S. Y. Strauss

Faculty Publications

Beta-delayed-neutron (βn) spectroscopy was performed using the Beta-decay Paul Trap and an array of radiation detectors. The βn branching ratios and energy spectra for Sb135,136 and I140 were obtained by measuring the time of flight of recoil ions emerging from the trapped ion cloud. These nuclei are located at the edge of an isotopic region identified as having βn branching ratios that impact the r-process abundance pattern around the A≈130 peak. For Sb135,136 and I140, βn branching ratios of 14.6(13)%, 17.6(29)%, and 7.6(28)% were determined, respectively. The βn energy spectra obtained for Sb135 and I140 are compared with results from …

Comparing Observed Stellar Kinematics And Surface Densities In A Low-Latitude Bulge Field To Galactic Population Synthesis Models, Sean K. Terry, Richard K. Barry, David P. Bennett, Aparna Bhattacharya, Jay Anderson, Matthew T. Penny

Faculty Publications

We present an analysis of Galactic bulge stars from Hubble Space Telescope Wide Field Camera 3 observations of the Stanek window (l, b = [0.25,-2.15]) from two epochs approximately two years apart. This data set is adjacent to the provisional Wide-field Infrared Survey Telescope (WFIRST) microlensing field. Proper motions are measured for approximately 115,000 stars down to 28th mag in V band and 25th mag in I band, with accuracies of 0.5 mas yr-1 (20 km s-1) at I ≈ 21. A cut on the longitudinal proper motion μ l allows us to separate disk and bulge populations and produce …

Identification Of A Pai-1-Binding Site Within An Intrinsically Disordered Region Of Vitronectin, Yuzhuo Chu, Joel C. Bucci, Cynthia B. Peterson

Faculty Publications

© 2019 The Protein Society The serine protease inhibitor, plasminogen activator inhibitor Type-1 (PAI-1) is a metastable protein that undergoes an unusual transition to an inactive conformation with a short half-life of only 1–2 hr. Circulating PAI-1 is bound to a cofactor vitronectin, which stabilizes PAI-1 by slowing this latency conversion. A well-characterized PAI-1-binding site on vitronectin is located within the somatomedin B (SMB) domain, corresponding to the first 44 residues of the protein. Another PAI-1 recognition site has been identified with an engineered form of vitronectin lacking the SMB domain, yet retaining PAI-1 binding capacity (Schar, Blouse, Minor, Peterson. …

Mud Deposition And Diagenesis Within An Early Palaeozoic Clinothem: Power Steps Formation, Newfoundland, Canada, Kathryn C. Denommee, Dario Harazim, Samuel J. Bentley, James H. Macquaker, Stefanie Lode, Babatunde John Olanipekun

Faculty Publications

© Cambridge University Press 2019. The early Ordovician (∼385 Ma) Power Steps Formation, Newfoundland, Canada, exposes a well-preserved mudstone-dominated clinothem that serves as an excellent archive for understanding how mud has been produced, transported and converted into mudstone prior to the evolution of globally widespread, deep soil horizons. Sedimentological analysis of four sandstone and five mudstone facies, along the Ochre Cove clinothem, reveal that mud and sand were delivered by unidirectional currents and experienced episodic reworking by storm waves. Petrographic examination and X-ray diffraction from described mudstone facies reveal significant variability in the distribution of illite versus chlorite between the …

Numerical Experiments On Variation Of Freshwater Plume And Leakage Effect From Mississippi River Diversion In The Lake Pontchartrain Estuary, Wei Huang, Chunyan Li, John R. White, Sibel Bargu, Brian Milan, Sam Bentley

Faculty Publications

©2020. American Geophysical Union. All Rights Reserved. A Finite Volume Community Ocean Model is used to investigate how wind impacts the circulation and evolution of a freshwater plume from Mississippi River diversion in the Lake Pontchartrain Estuary. Results show that northerly and southerly winds tend to stretch the plume in the east-west directions, while easterly and westerly winds constrain the plume in the north-south directions. Increasing wind magnitude tends to increase the total salt content of the estuary except under weak westerly wind (/s) during which salt content decreases. A no-motion middepth interface is found (by the model and verified …

Erratum: The Extended Specimen Network: A Strategy To Enhance Us Biodiversity Collections, Promote Research And Education (Bioscience Doi: 10.1093/Biosci/Biz140, James Lendemer, Barbara Thiers, Anna K. Monfils, Jennifer Zaspel, Elizabeth R. Ellwood, Andrew Bentley, Katherine Levan, John Bates, David Jennings, Dori Contreras, Laura Lagomarsino, Paula Mabee, Linda S. Ford, Robert Guralnick, Robert E. Gropp, Marcy Revelez, Neil Cobb, Katja Seltmann, M. Catherine Aime

Faculty Publications

© 2020 The Author(s). In a recent article (doi:10.1093/biosci/biz140), in the original publication of this report, Marcy Revelez's affiliation was listed as the Centers for Disease Control and Prevention, Atlanta, GA 30333. It has since been changed to correctly reflect affiliation with Museum of Texas Tech University, Lubbock, TX 79409-3191.

Mixed Perverse Sheaves On Flag Varieties For Coxeter Groups, Pramod N. Achar, Simon Riche, Cristian Vay

Faculty Publications

In this paper we construct an abelian category of mixed perverse sheaves attached to any realization of a Coxeter group, in terms of the associated Elias-Williamson diagrammatic category. This construction extends previous work of the first two authors, where we worked with parity complexes instead of diagrams, and we extend most of the properties known in this case to the general setting. As an application we prove that the split Grothendieck group of the Elias-Williamson diagrammatic category is isomorphic to the corresponding Hecke algebra, for any choice of realization.

The Response Of Stomatal Conductance To Seasonal Drought In Tropical Forests, Jin Wu, Shawn P. Serbin, Kim S. Ely, Brett T. Wolfe, L. Turin Dickman, Charlotte Grossiord, Sean T. Michaletz, Adam D. Collins, Matteo Detto, Nate G. Mcdowell, S. Joseph Wright, Alistair Rogers

Faculty Publications

Stomata regulate CO2 uptake for photosynthesis and water loss through transpiration. The approaches used to represent stomatal conductance (gs) in models vary. In particular, current understanding of drivers of the variation in a key parameter in those models, the slope parameter (i.e. a measure of intrinsic plant water-use-efficiency), is still limited, particularly in the tropics. Here we collected diurnal measurements of leaf gas exchange and leaf water potential (Ψleaf), and a suite of plant traits from the upper canopy of 15 tropical trees in two contrasting Panamanian forests throughout the dry season of the 2016 El Niño. The plant traits …

Body Composition During Pregnancy Differs By Obesity Class, Jasper Most, Abby D. Altazan, Daniel S. Hsia, Robbie A. Beyl, Leanne M. Redman

Clinical Research Faculty Publications

Objective: The aim of this study is to characterize changes in body composition during pregnancy in women with obesity. Methods: Fifty-four healthy women with obesity (class 1, 30-34.9 kg/m2: n = 25; class 2, 35-39.9 kg/m2: n = 21; class 3, ≥ 40.0 kg/m2: n = 8) expecting a singleton pregnancy were studied. Body composition was measured in early pregnancy (13-16 weeks), midpregnancy (24-27 weeks), and late pregnancy (35-37 weeks) using air displacement plethysmography, stable isotopes, and skinfold thickness measurements. Fasting glucose, insulin, and leptin were measured. Results: The gain in fat-free mass was lower in the second trimester compared …

Pattern Of Regional White Matter Hyperintensity Volume In Mild Cognitive Impairment Subtypes And Associations With Decline In Daily Functioning, Katherine J. Bangen, Kelsey R. Thomas, Alexandra J. Weigand, Danielle L. Sanchez, Lisa Delano-Wood, Emily C. Edmonds, Owen T. Carmichael, Christopher G. Schwarz, Adam M. Brickman, Mark W. Bondi

Clinical Research Faculty Publications

White matter hyperintensities (WMHs), a marker of small-vessel cerebrovascular disease, increase risk for mild cognitive impairment (MCI). Less is known about whether regional WMHs distinguish MCI subtypes and predict decline in everyday functioning. About 618 Alzheimer's Disease Neuroimaging Initiative participants (301 cognitively normal [CN]; 232 amnestic MCI [aMCI]; 85 nonamnestic MCI [naMCI]) underwent neuropsychological testing, MRI, and assessment of everyday functioning. aMCI participants showed greater temporal (p = 0.002) and occipital WMHs (p = 0.030) relative to CN whereas naMCI participants had greater frontal (p = 0.045), temporal (p = 0.003), parietal (p = 0.018), and occipital (p < 0.001) WMH compared with CN. Relative to those with aMCI, individuals with naMCI showed greater occipital WMH (p = 0.013). Greater WMH in temporal (p = 0.001) and occipital regions (p = 0.006) was associated with faster decline in everyday functioning across the sample. Temporal lobe WMHs were disproportionately associated with accelerated functional decline among naMCI (p = 0.045). Regional WMH volumes vary across cognitive groups and predict functional decline. Cerebrovascular markers may help identify individuals at risk for decline and distinguish subtypes of cognitive impairment.

Γ -Ray Spectroscopy Of Astrophysically Important States In Ca 39, M. R. Hall, D. W. Bardayan, T. Baugher, A. Lepailleur, S. D. Pain, A. Ratkiewicz, S. Ahn, J. M. Allen, J. T. Anderson, A. D. Ayangeakaa, J. C. Blackmon, S. Burcher, M. P. Carpenter, S. M. Cha, K. Y. Chae, K. A. Chipps, J. A. Cizewski, M. Febbraro, O. Hall, J. Hu, C. L. Jiang, K. L. Jones, E. J. Lee, P. D. O'Malley, S. Ota, B. C. Rasco, D. Santiago-Gonzalez, D. Seweryniak, H. Sims, K. Smith, W. P. Tan, P. Thompson, C. Thornsberry

Faculty Publications

Background: Nova explosions synthesize elements up to A≃40, and discrepancies exist between calculated and observed abundances of Ar and Ca created in the explosion. The K38(p,γ)Ca39 reaction rate has been shown to be influential on these isotopic abundances at the endpoint of nova nucleosynthesis. The energies of the three most important resonances, corresponding to Jπ=5/2+ excited states in the Ca39 nucleus above the proton separation threshold, are uncertain and one has been measured with conflicting values [Er=679(2) versus Er=701(2) keV] in previous experiments. Purpose: Reducing the uncertainties on the resonance energies would allow for a better understanding of the reaction …

Synthesis And Preliminary Ex Vivo Testing Of Sirna Targeting Tcrb: A Proposed Therapy For The Treatment Of Autoimmunity, Nicholas J. Magazine

LSU Doctoral Dissertations

Abstract

Background:

As of 2018, the United States National Institutes of Health estimate that over half a billion people worldwide are affected by autoimmune disorders. Though these conditions are prevalent, treatment options remain relatively poor, relying primarily on various forms of immunosuppression which carry potentially severe side effects and often lose effectiveness overtime. Given this, new forms of therapy are needed. We propose small-interfering RNA (siRNA) for hypervariable regions of the T-cell receptor β-chain gene (TCRb) as a highly targeted, novel means of therapy for the treatment of autoimmune disorders.

Objectives:

To develop methods to produce siRNA targeting …

Examining Interaction Effects In 2d Fermi Gases Using Renormalization Group Theory, Sri Laalitya Uppalapati

LSU Doctoral Dissertations

We use the Renormalization Group (RG) method within the perturbation theory framework to study properties of a balanced, two-dimensional Fermi gas with short-range, attractive interactions in non-superfluid (normal) phase. We find that the RG method allows for the evaluation of logarithmic corrections to Equations of State in various regimes of density and temperature. We present two calculations using RG with perturbation theory. The first being a simplified RG scheme with an interpolation of crossover between RG flow in different regimes. The second calculation features a rigorous derivation whereby the Green's function within a standard perturbation theory is renormalized to derive …

A Hop-By-Hop Relay Selection Strategy In Multi-Hop Cognitive Relay Networks, Hui Sun, Mort Naraghi-Pour, Weixing Sheng, Renli Zhang

Faculty Publications

In this paper, a hop-by-hop relay selection strategy for multi-hop underlay cognitive relay networks (CRNs) is proposed. In each stage, relays that successfully decode the message from previous hop form a decoding set. Taking both maximum transmit power and maximum interference constraints into consideration, the relay in the decoding set which has the largest number of channels with an acceptable signal-to-noise ratio (SNR) level to the relays in the next stage is selected for retransmission. Therefore, relay selection in each stage only relies on channel state information (CSI) of the channels in that stage and does not require the CSI …

Soil Health On A Small-Scale Sustainable Vegetable Farm In South Louisiana, Allison Guidroz

LSU Master's Theses

One of the biggest challenges facing the world today is the need to provide nutritious food to an ever-growing population in a way that does not compromise the ecosystem services of the soil that are necessary for life. The evidence for widespread degradation of the soil has been a major contributor in the increased interest in soil health. Most of the research in soil health has focused on field crops, which has led to a gap in the research of soil health on vegetable cropping systems. This objective of this study was to analyze the health of the soil on …

Calibration Transients In Ligo Detectors, Thomas Daniel Abbott

LSU Doctoral Dissertations

This dissertation describes a novel method of analyzing fluctuations in the time-dependent calibration models of the LIGO interferometers to estimate their effect on strain reconstruction for gravitational-wave detections. The time-dependence of the calibration model of each detector is tracked with a set of parameters which are continuously measured while the interferometers are operating. These parameters track slow variations in the sensing function of the detectors as well as the actuators that hold the detectors in an operational state. The time-dependent parameter data during the second observation run (O2 [November 30, 2016 16:00 UTC to August 25, 2017 22:00:00 UTC]) and …

Calorimetry For Low-Energy Electrons Using Charge And Light In Liquid Argon, W. Foreman, R. Acciarri, J. A. Asaadi, W. Badgett, F. D.M. Blaszczyk, R. Bouabid, C. Bromberg, R. Carey, F. Cavanna, J. I. Cevallos Aleman, A. Chatterjee, J. Evans, A. Falcone, W. Flanagan, B. T. Fleming, D. Garcia-Gamez, B. Gelli, T. Ghosh, R. A. Gomes, E. Gramellini, R. Gran, P. Hamilton, C. Hill, J. Ho, J. Hugon, E. Iwai, E. Kearns, E. Kemp, T. Kobilarcik, M. Kordosky, P. Kryczyński, K. Lang, R. Linehan

Faculty Publications

Precise calorimetric reconstruction of 5-50 MeV electrons in liquid argon time projection chambers (LArTPCs) will enable the study of astrophysical neutrinos in DUNE and could enhance the physics reach of oscillation analyses. Liquid argon scintillation light has the potential to improve energy reconstruction for low-energy electrons over charge-based measurements alone. Here we demonstrate light-augmented calorimetry for low-energy electrons in a single-phase LArTPC using a sample of Michel electrons from decays of stopping cosmic muons in the LArIAT experiment at Fermilab. Michel electron energy spectra are reconstructed using both a traditional charge-based approach as well as a more holistic approach that …

Emerson's Idealist Poetics: Emerson, Rödl, And The Life Of Nature, Robert Darren Hutchinson

LSU Doctoral Dissertations

In this dissertation, I articulate a hermeneutics for reading Ralph Waldo Emerson’s seminal text Nature through drawing on the insights of the contemporary philosopher Sebastian Rödl. Particularly, the performative, literary characteristics of Rödl’s quite conceptual work resonate with the poetic strategies that Emerson employs in Nature. In the section on the work of Rödl, I make the performative aspects of his philosophy explicit through a close reading of the way self-consciousness happens in his texts through the language he employs. Rödl refers to his elucidation of self-consciousness as idealism. In the section on Emerson, I show how Emerson’s project …

Measurement Of The Muon Neutrino Charged-Current Single Π+ Production On Hydrocarbon Using The T2k Off-Axis Near Detector Nd280, K. Abe, R. Akutsu, A. Ali, C. Alt, J. Amey, C. Andreopoulos, L. Anthony, M. Antonova, S. Aoki, A. Ariga, Y. Ashida, E. T. Atkin, Y. Awataguchi, Y. Azuma, S. Ban, M. Barbi, G. J. Barker, G. Barr, C. Barry, M. Batkiewicz-Kwasniak, A. Beloshapkin, F. Bench, V. Berardi, S. Berkman, R. M. Berner, L. Berns, S. Bhadra, S. Bienstock

Faculty Publications

We report the measurements of the single and double differential cross section of muon neutrino charged-current interactions on carbon with a single positively charged pion in the final state at the T2K off-axis near detector using 5.56×1020 protons on target. The analysis uses data control samples for the background subtraction and the cross section signal, defined as a single negatively charged muon and a single positively charged pion exiting from the target nucleus, is extracted using an unfolding method. The model-dependent cross section, integrated over the T2K off-axis neutrino beam spectrum peaking at 0.6 GeV, is measured to be σ=(11.76±0.44(stat)±2.39(syst))×10-40 …

The Desorption Kinetics Of Methane From Nonaqueous Fluids For Enhanced Well Control, James Lee Nielsen Jr.

LSU Master's Theses

The mass transfer of a dissolved gas evolving to return to the gaseous phase from a liquid is governed by many parameters. This process affects the development of an oil and gas well due to the possibility of gas contamination occurring from either an influx entering the wellbore, or drilling through gas-bearing formations. Once this dissolved hydrocarbon gas circulates up the wellbore, it will begin to evolve from solution and poses a potential risk to drilling equipment, the environment, and personnel at a drilling rig. Being able to predict the behavior of gas desorption based on a known set of …

First-Principle Study On The Interaction Of Ligands With Gold And Effects On Catalytic Activities, Xun Cheng

LSU Doctoral Dissertations

The extensive use of fossil fuels has increased the atmospheric concentration of CO₂, resulting in global climate change. One way to mitigate the CO₂ challenge is to convert it into useful chemicals electrocatalytically using renewable energies. Recent studies suggest that ligand-modified gold electrodes can enhance the Faradaic efficiency (FE) and selectivity of the electrochemical CO₂ reduction reaction (CO₂RR). This theoretical research, primarily based on density functional theory (DFT), has been carried out to understand the interactions of ligands with Au and possible effects on electrocatalytic activities. We systematically modeled and studied the adsorption of …

A Robust Solver For A Second Order Mixed Finite Element Method For The Cahn–Hilliard Equation, Susanne C. Brenner, Amanda E. Diegel, Li Yeng Sung

Faculty Publications

We develop a robust solver for a second order mixed finite element splitting scheme for the Cahn–Hilliard equation. This work is an extension of our previous work in which we developed a robust solver for a first order mixed finite element splitting scheme for the Cahn–Hilliard equation. The key ingredient of the solver is a preconditioned minimal residual algorithm (with a multigrid preconditioner) whose performance is independent of the spatial mesh size and the time step size for a given interfacial width parameter. The dependence on the interfacial width parameter is also mild.

Spatial And Topological Analysis Of Urban Land Cover Structure In New Orleans Using Multispectral Aerial Image And Lidar Data, Shuxian Liu

LSU Master's Theses

Urban land use and land cover (LULC) mapping has been one of the major applications in remote sensing of the urban environment. Land cover refers to the biophysical materials at the surface of the earth (i.e. grass, trees, soils, concrete, water), while land use indicates the socio-economic function of the land (i.e., residential, industrial, commercial land uses). This study addresses the technical issue of how to computationally infer urban land use types based on the urban land cover structures from remote sensing data. In this research, a multispectral aerial image and high-resolution LiDAR topographic data have been integrated to investigate …

Structural Analysis Of Ultrasoft Pdms- G-Pdms Shell-Only Particles, Karin J. Bichler, Bruno Jakobi, Stefan O. Huber, Elliot P. Gilbert, Gerald J. Schneider

Faculty Publications

Copyright © 2019 American Chemical Society. We have used anionic polymerization to synthesize polymers of linear and bottlebrush architecture each with a polydimethylsiloxane backbone. The blending of polymer architectures has the effect of changing material properties, e.g., the viscoelasticity, which are connected to the chain conformation. Thus, we explore the conformation of bottlebrush polymers in a linear host melt both as a function of the concentration and for various molecular weights of the linear host matrices. Our bottlebrush polymers are seen as shell-only particles with a negligible core size. We find a substantial influence of the molecular weight of the …

Interactions Among Amygdala Volume, Cortical Thickness, And Structural Connectivity In Youth: Relationship To Emotion Regulation, Peter James Castagna

LSU Doctoral Dissertations

Emotion regulation includes adaptive (e.g., reappraisal) and non-adaptive behaviors (e.g., avoidance) designed to alter ones’ affective responses. The central hypothesis is that emotional consciousness – being self-aware that you are currently in a particular emotional state – and emotion regulation share the same underlying brain mechanisms/networks. In addition, it is argued that the more appropriate dichotomy, in regard to non-adaptive and adaptive emotion regulation strategies, is dependent on whether they are unconscious or conscious (respectively), positing a two-system framework of emotion regulation. Evidence for the proposed framework draws and builds off of recent theories of higher-order emotional consciousness (LeDoux & …

A Study Of Particle-Laden Flows From Meso And Micro-Scale Perspectives, Daniel Guedes De Oliveira

LSU Doctoral Dissertations

Particle-laden flows are investigated numerically from a meso-scale perspective using Computational Fluid Dynamics coupled with Discrete Element Method (CFD-DEM) and from a micro-scale perspective using Particle Resolved Direct Numerical Simulation (PR-DNS). For the former, the dynamics of a pseudo-2D pulsed fluidized bed (PFB) consisting of 400,000 to 800,000 particles was investigated (Chapters 2 and 3). The focus is on the capabilities of CFD-DEM to (1) reproduce pattern formation in these systems and (2) further the understanding of the dynamics of PFB's as a function of pulsation parameters. In Chapter 4, a two-spheres system is investigated with a recently implemented PR-DNS …