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Gw Covid-19 Intelligence Reports: June 29, 2020, George Washington University

GW COVID-19 Intelligence Reports

No abstract provided.

Current Status Of Serologic Testing For Covid-19, George Washington University

Intelligence Unit Research Briefs

No abstract provided.

Covid-19 Clinical Update 5/21/2020, George Washington University

GW Infectious Disease Updates

No abstract provided.

Gw Covid-19 Intelligence Reports: May 18, 2020, George Washington University

GW COVID-19 Intelligence Reports

No abstract provided.

Covid-19 Clinical Update 5/14/2020, George Washington University

GW Infectious Disease Updates

No abstract provided.

Gw Covid-19 Intelligence Reports: May 11, 2020, George Washington University

GW COVID-19 Intelligence Reports

No abstract provided.

Ppe For Endotracheal Intubation, George Washington University

Intelligence Unit Research Briefs

No abstract provided.

Covid-19 Clinical Update 4/30/2020, George Washington University

GW Infectious Disease Updates

No abstract provided.

Gw Covid-19 Intelligence Reports: April 27, 2020, George Washington University

GW COVID-19 Intelligence Reports

No abstract provided.

Gw Covid-19 Intelligence Reports: April 20, 2020, George Washington University

GW COVID-19 Intelligence Reports

No abstract provided.

Gw Covid-19 Intelligence Reports: April 4, 2020, George Washington University

GW COVID-19 Intelligence Reports

No abstract provided.

Gw Covid-19 Intelligence Reports: April 3, 2020, George Washington University

GW COVID-19 Intelligence Reports

No abstract provided.

Public Health Research Day 2020, George Washington University

GW Research Days 2016 - 2020

No abstract provided.

The Gw School Of Medicine And Health Sciences Medical Student Research Day, George Washington University

GW Research Days 2016 - 2020

No abstract provided.

Educational Session To Improve The Knowledge And Confidence Of State Agency Surveyors In Deficiency Citation Of Immediate Jeopardy Findings In Nursing Homes, Aileen Renolayan, Msn, Ma, Rn, Phn

Doctor of Nursing Practice Projects

Background: The oversight of nursing homes is a shared federal-state responsibility. Under the agreement with Centers for Medicare and Medicaid Services (CMS, 2018), state survey agencies assess nursing homes using standard surveys. Several studies indicate that the type of deficiencies issued to nursing facilities varies significantly by state, suggesting inconsistency in the survey process for issuing deficiencies. For example, variation in Immediate Jeopardy (IJ) citations among state agency surveyors has been the subject of reports from the Government Accountability Office (GAO, 2019) and the Office of the Inspector General (OIG, 2014).

Objective: To determine if a 1-hour educational session about …

Increasing Adult Influenza Vaccination Rates In The Primary Care Setting, Leah Prescott Msn, Fnp-Bc

Doctor of Nursing Practice Projects

Background: Provision of vaccinations is one of the most basic interventions aimed at health promotion and disease prevention in the primary care setting. Despite increased public awareness and improved access to vaccinations through minute-clinic settings, health fairs, and employer-offered vaccination clinics, adults in the United States continue to fall short of national goals. Literature demonstrates vaccination rates among adults vary widely and may be affected by a multitude of factors, however vaccination rates may be greatly improved with increased provider engagement.

Objectives: The purpose of this project was to develop, implement, and evaluate a program to improve immunization rates in …

The Development, Implementation And Evaluation Of An Evidence-Based Biohazard Training Program Within A Pediatric Ambulatory Practice, Lakeshia L. Evans Mba, Fnp-Bc

Doctor of Nursing Practice Projects

Background: Communicable disease(s) such as Ebola or Coronavirus can cause a catastrophic health crisis within the United States healthcare system, especially among the pediatric and elderly population. Lack of knowledge, skills and confidence among health care professionals in the pediatric setting regarding these infectious organisms can affect early identification, proper isolation, early treatment, and increased risk of a possible pandemic and/or fatalities.

Aims/Objectives: The aim of this study was to develop, implement and evaluate an evidence-based biohazard training program-using the Identify, Isolate and Inform (3I) tool within a pediatric urgent care center to increase the staff’s knowledge, skills and confidence …

Covid-19 Clinical Update 3/19/2020, George Washington University

GW Infectious Disease Updates

No abstract provided.

Covid-19 Clinical Update 3/17/2020, George Washington University

GW Infectious Disease Updates

No abstract provided.

Fusion, 2020, George Washington University, William H. Beaumont Medical Research Honor Society

Fusion

No abstract provided.

Medicine + Health Magazine, Spring 2019, George Washington University, School Of Medicine And Health Sciences, Office Of Communications And Marketing

Medicine + Health Magazine

No abstract provided.

"As Parents, How On Earth Are We Going To Handle This Issue": Provider And Parent Views On Sexuality-Related Challenges During Adolescence Among International Hiv-Infected Adoptees In The U.S., Sarah Alger, Cynthia Fair

GW Research Days 2016 - 2020

As the number of internationally adopted children with HIV has increased since 2010 in the U.S., more children may have additional educational needs, particularly related to sexuality, as they mature. After conducting 48 hour-long, semi-structured interviews with parents and providers, the qualitative analysis shows that many parents' adoption decisions are driven by faith, which can influence the child's ability to gain vital sexual education given their HIV status. Parents of internationally adopted children with HIV could benefit from the support of healthcare providers to better understand the importance of sexual and reproductive health during adolescence.

Gw Nursing, Spring 2019, George Washington University, School Of Nursing

GW Nursing Magazine

No abstract provided.

Reducing Unnecessary Phlebotomy Testing Using A Clinical Decision Support System, Valerie Strockbine Msn, Rn, Cphq

Doctor of Nursing Practice Projects

Background: Overuse of phlebotomy testing offers little to improve patient outcomes. Reducing unnecessary phlebotomy tests can cut costs without compromising quality.

Purpose: To determine the effectiveness of a clinical decision support system (CDSS) on reducing unnecessary type and screen tests, estimate the cost saved by the CDSS implementation, and describe the unnecessary ordering practices by provider type.

Methods: Our study used a separate-sample pretest posttest design at a mid-Atlantic academic medical center to examine the number of unnecessary type and screen tests three months before and after CDSS implementation. A CDSS was embedded in our electronic health record. The CDSS …

Analysis Of Parental Attitudes Of Adolescent Vaccinations In The Retail Health Care Setting, Patrick William Denning Mph, Msn

Doctor of Nursing Practice Projects

Background: The tetanus-diphtheria-acellular pertussis, meningococcal, and human papillomavirus vaccines have been recommended for adolescents since 2005. Retail health clinics can increase the delivery of vaccinations by reaching patients outside the traditional healthcare system.

Objectives: To measure parental attitudes of adolescent vaccinations utilizing the Vaccine Confidence Scale (VCS) and assess reasons parents decided to vaccinate or not. Attitudes were compared to previous studies. Our long-term purpose was to develop targeted interventions to increase adolescent vaccinations.

Methodology: A descriptive survey design measured the parental attitudes of adolescent vaccinations from total VCS scores and subscale scores of benefits, harms, and trust. A qualitative …

Fusion, 2019, George Washington University, William H. Beaumont Medical Research Honor Society

Fusion

No abstract provided.

Safety, Tolerability, And Pharmacokinetics Of Long-Acting Injectable Cabotegravir In Low-Risk Hiv-Uninfected Individuals: Hptn 077, A Phase 2a Randomized Controlled Trial., Raphael J Landovitz, Sue Li, Beatriz Grinsztejn, Halima Dawood, Albert Y Liu, Manya Magnus, Mina C Hosseinipour, Ravindre Panchia, Leslie Cottle, Gordon Chau, Paul Richardson, Mark A Marzinke, Craig W Hendrix, Susan H Eshleman, Yinfeng Zhang, Elizabeth Tolley, Jeremy Sugarman, Ryan Kofron, Adeola Adeyeye, David Burns, Alex R Rinehart, David Margolis, William R Spreen, Myron S Cohen, Marybeth Mccauley, Joseph J Eron

Epidemiology Faculty Publications

BACKGROUND: Cabotegravir (CAB) is a novel strand-transfer integrase inhibitor being developed for HIV treatment and prevention. CAB is formulated both as an immediate-release oral tablet for daily administration and as a long-acting injectable suspension (long-acting CAB [CAB LA]) for intramuscular (IM) administration, which delivers prolonged plasma exposure to the drug after IM injection. HIV Prevention Trials Network study 077 (HPTN 077) evaluated the safety, tolerability, and pharmacokinetics of CAB LA in HIV-uninfected males and females at 8 sites in Brazil, Malawi, South Africa, and the United States.

METHODS AND FINDINGS: HPTN 077 was a double-blind, placebo-controlled phase 2a trial. Healthy …

Atherosclerosis In Subjects Newly Diagnosed With Human Immunodeficiency Virus Infection., Tatiana V Kirichenko, Veronika A Myasoedova, Tatiana E Shimonova, Alexandra A Melnichenko, Dmitri Sviridov, Igor A Sobenin, Alexey I Mazus, Alexander N Orekhov, Michael I Bukrinsky

Microbiology, Immunology, and Tropical Medicine Faculty Publications

HIV infection is associated with the increased risk of cardiovascular disease (CVD), even in patients successfully treated with the combination antiretroviral therapy (cART). However, the relationship between HIV, cART, and pathogenesis of CVD remains controversial. In the present study, we evaluated the carotid intima-media thickness (CIMT), a surrogate marker of atherosclerosis, in HIV-infected subjects receiving or not receiving cART. One hundred nine newly diagnosed HIV-infected subjects and one hundred nine uninfected age-matched controls (all males) without the history of CVD, hypertension, or diabetes were recruited into the present study. Cross-sectional analysis at baseline (BL) showed significantly increased levels of triglycerides …

Gw Nursing, Summer 2018, George Washington University, School Of Nursing

GW Nursing Magazine

No abstract provided.

Tgf-Β Sustains Tumor Progression Through Biochemical And Mechanical Signal Transduction., Robert L Furler, Douglas F Nixon, Christine A Brantner, Anastas Popratiloff, Christel H Uittenbogaart

Microbiology, Immunology, and Tropical Medicine Faculty Publications

Transforming growth factor β (TGF-β) signaling transduces immunosuppressive biochemical and mechanical signals in the tumor microenvironment. In addition to canonical SMAD transcription factor signaling, TGF-β can promote tumor growth and survival by inhibiting proinflammatory signaling and extracellular matrix (ECM) remodeling. In this article, we review how TGF-β activated kinase 1 (TAK1) activation lies at the intersection of proinflammatory signaling by immune receptors and anti-inflammatory signaling by TGF-β receptors. Additionally, we discuss the role of TGF-β in the mechanobiology of cancer. Understanding how TGF-β dampens proinflammatory responses and induces pro-survival mechanical signals throughout cancer development is critical for designing therapeutics that …