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A General Synthesis Of Bis-Indolylpiperazine-2,5-Diones, Stephen N. Crooke, Christine Whitlock

Chemistry: Faculty Publications (1990-2023)

The one-pot synthesis of three dragmacidin derivatives is reported. Sarcosine anhydride (4) is brominated and immediately reacted with the corresponding indole to produce the products, namely 3,6-bis(5′-methoxy-3′-indolyl)-1,4-dimethylpiperazine-2,5-dione (1), 3,6-bis(7′-methyl-3′-indolyl)-1,4-dimethylpiperazine-2,5-dione (2) and 3,6-bis-(6′-chloro-3′-indolyl)-1,4-dimethylpiperazine-2,5-dione (3), which are characterized by ¹H-NMR.

Case Study Of A Shoe-String Sotl Center, Philip T. Dunwoody, Kathryn Westcott, David Drews, Jay Hosler

International Journal for the Scholarship of Teaching & Learning

This paper provides a case study of a faculty-driven, cost-effective center focused on the Scholarship of Teaching and Learning (SoTL) at a small private liberal arts college. Prior work on teaching and learning centers has focused on large institutions. Our case study shows that a “teaching commons” (Huber & Hutchings, 2006) can be created at a small college (approximately 1600 students) with relatively little expense. Thanks to a grant from the Teagle Foundation, we were able to establish a SoTL center focused on the dissemination and production of SoTL. The center sponsors a biweekly lunch series (with 25% of the …

President's Annual Report, Brooks Keel

Office of the President: Annual Report (Archived)

No abstract provided.

Evaluating Relationships Between Mercury Concentrations In Air And In Spanish Moss (Tillandsia Usneoides L.), Kathryn T. Sutton

College of Graduate Studies: Theses & Dissertations

Mercury is a potent neurotoxin that is transported globally in vapor form. A major source of mercury contamination to soil, water, and biota is atmospheric deposition. Therefore, comprehensive monitoring of atmospheric concentrations is important. Limitations of conventional atmospheric measurement techniques include high cost and lack of temporal or spatial integration. Bioindicators, however, may serve as an integrative tool to add to conventional mercury measurement techniques. Spanish moss (Tillandsia usneoides L.) is a potential bioindicator of atmospheric mercury concentration in the southeastern United States because it is an abundant epiphyte that absorbs and accumulates atmospheric pollutants. A study was conducted in …

A Hemoglobin-Based Multifunctional Therapeutic: Polynitroxylated Pegylated Hemoglobin, Carleton C. J. Hsia, Li Ma

Physics & Astronomy: Faculty Publications

Polynitroxylated pegylated hemoglobin (PNPH) as a multifunctional therapeutic takes advantage of the ability of hemoglobin (Hb) to transport oxygen, the antioxidative stress activities from the redox coupling of nitroxide and heme iron, and the hypercolloid properties of pegylation. The published preclinical data demonstrating that PNPH acts as a neurovascular protective multifunctional therapeutic in an animal model simulating prehospital resuscitation of traumatic brain injury (TBI) with hemorrhagic shock (HS) are reviewed. Preliminary results on the potential utility of PNPH for neurovascular protection in thrombolytic stroke therapy and for correction of vascular dysfunction through transfusion in sickle-cell disease (SCD) are also discussed. …

Polynitroxyl Albumin And Albumin Therapy After Pediatric Asphyxial Cardia Arrest: Effects On Cerebral Blood Flow And Neurologic Outcome, Mioara D. Manole, Patrick M. Kochanek, Lesley M. Foley, T. Kevin Hitchens, Hülya Bayır, Henry Alexander, Robert Garman, Li Ma, Carleton J. C. Hsia, Chien Ho, Robert S. B. Clark

Physics & Astronomy: Faculty Publications

Postresuscitation cerebral blood flow (CBF) disturbances and generation of reactive oxygen species likely contribute to impaired neurologic outcome after pediatric cardiac arrest (CA). Hence, we determined the effects of the antioxidant colloid polynitroxyl albumin (PNA) versus albumin or normal saline (NS) on CBF and neurologic outcome after asphyxial CA in immature rats. We induced asphyxia for 9 minutes in male and female postnatal day 16 to 18 rats randomized to receive PNA, albumin, or NS at resuscitation from CA or sham surgery. Regional CBF was measured serially from 5 to 150 minutes after resuscitation by arterial spin-labeled magnetic resonance imaging. …

2011-2012 Georgia Southern University Women's Basketball Media Guide, Georgia Southern University

Women's Basketball Records

• 2011-12 Georgia Southern Women's Basketball Media Guide

Graduate Catalog, Georgia Southern University

Graduate Catalogs

No abstract provided.

Estimating Population Exposure To Fine Particulate Matter In The Conterminous U.S. Using Shape Function-Based Spatiotemporal Interpolation Method: A County Level Analysis, Lixin Li, Xingyou Zhang, James B. Holt, Jie Tian, Reinhard Piltner

Mathematical Sciences: Faculty Publications

This paper investigates spatiotemporal interpolation methods for the application of air pollution assessment. The air pollutant of interest in this paper is fine particulate matter PM_2.5. The choice of the time scale is investigated when applying the shape function-based method. It is found that the measurement scale of the time dimension has an impact on the quality of interpolation results. Based upon the result of 10-fold cross validation, the most effective time scale out of four experimental ones was selected for the PM_2.5 interpolation. The paper also estimates the population exposure to the ambient air pollution of …

Assessing The Degree Of Integrated Learner-Centered Instruction On Student Outcomes In A Large Non-Major Environmental Science Course, Ruthanne “Rudi” Thompson, Greta Bolin, Alice Coe

International Journal for the Scholarship of Teaching & Learning

The decision to employ learner-centered teaching methods, teacher-centered teaching methods, or whether to integrate the two within large lecture halls in higher education continues to be heavily researched and hotly debated. All, in one form or another, have been shown effective at varying levels, throughout a myriad of disciplines and across diverse cultures. Yet there are fewer quantitative studies assessing the effects of implementing varying degrees of integrated learner-centered methods within large classroom environments. To that end, this study compared two sections of an undergraduate non-major environmental science large lecture course. One section received a minimal degree of learner-centered (MLC) …

Comparative Analysis Of Microsatellite And Mitochondrial Genetic Variation In Ixodes Scapularis, Cynthia Tak Wan Chan

College of Graduate Studies: Theses & Dissertations

Ixodes scapularis, the black legged tick, is a species endemic to North America with a range including most of the eastern-half of the United States and portions of Canada and Mexico. The tick is an important vector of diseases transmitted to humans and animals. Since its first description in 1821, the taxonomy of the species has been controversial. Biological differences have been identified in the northern and southern populations, yet no consensus exists on population structure and the causes of this disparity. Earlier molecular studies utilizing nuclear and mitochondrial genetic markers have revealed the occurrence of two distinct lineages: …

Frankenfoods: Are We Bioengineering Our Children And What Can Curriculum Do?, Patra Rickman

College of Graduate Studies: Theses & Dissertations

In this dissertation I explore the effect of biotechnology and food production on children’s physical and mental health. What we eat affects our well-being and unknowingly, we have little control of what exactly we are consuming. Children have even less control and feel the effects of additives and chemicals more than adults. Many of the effects of bioengineered foods are unknown at this time. My dissertation will be a theoretical exploration of biotechnology in food using a bioethical critical perspective. I use my personal experience and research to examine the effects of processed and genetically engineered foods on people, especially …

2- Bromophenyl Salicylate, Donovan Thompson, Sierra Mitchell, Kevin Clarke, Kerry Sarden, Karelle Aiken

Chemistry: Faculty Publications (1990-2023)

2-Bromophenyl salicylate is synthesized from 2-benzyloxybenzoic acid in two steps. The final compound has been characterized by IR,¹H-NMR, ¹³C-NMR and HRMS. The melting point for 2-bromophenyl salicylate is provided.

Parent Perceptions Of The Georgia Special Needs Scholarship, Charity C. Roberts

College of Graduate Studies: Theses & Dissertations

Author's abstract: The purpose of this study was to understand both contributors and barriers to use of the Georgia Special Needs Scholarship (SB10). Although SB10 was designed to offer parental choice of schools for students with disabilities, it has diminished the capacity of parents to access due process granted through IDEA. Perspectives in this study were provided by parents who chose to rescind their child's participation in the voucher program and parents who continued to access the voucher. Analysis of the lived experiences of parents of students with disabilities in Georgia revealed both similar and diverse experiences, perceptions and concerns …

My Sister, Our Stories: Exploring The Lived Experience Of School Leavers Through Narrative And Poetics, C. Amelia Davis, Jennifer L. Pepperell

Curriculum, Foundations & Reading: Faculty Publications

The purpose of this study was to explore the educational experiences of two adult female siblings who are both school leavers. Through the use of thematic narrative analysis, sibling narratives and poetic re-presentations, their stories were developed. These stories represent the participants’ experiences of prior schooling and their current commitments to education. While each story conveyed a profound similarity in terms of prior schooling, contrasting narratives were illustrated through description of transitional moments and sibling relationship. The analysis also explored the intersections of race, gender,and social class within educative moments of the life experiences of the participants.

Gera Conference Program [2012], Gera

Georgia Educational Research Association Conference

Conference program for 2012.

Development Of High-Yielding Sweetgum Plantation Systems For Bioenergy Production In The Southeastern United States, Donald J. Kaczmarek, Brian C. Wachelka, Jeff Wright, Victor C. Steel, Doug P. Aubrey, David R. Coyle, Mark D. Coleman

Biology: Faculty Presentations

No abstract provided.

The George-Anne, Georgia Southern University

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A Psychoanalytic Inquiry Into Social Aggression As A Form Of Bullying Among Female Students, Tina Martin Debevec

College of Graduate Studies: Theses & Dissertations

Bullying among children and adolescents, particularly within the school setting, has drawn much attention in recent years as a reaction to an onslaught of high profile school violence in the 1990s. While much attention and research focused upon physical violence that was prevalent among male students, very little research covered indirect, relational, and social forms of aggression. Research into the covert manners of aggression that involved the manipulation of relationships revealed them to be salient among female students, demonstrating that female students were predominantly aggressive in a different manner than their male counterparts. Psychoanalytic theories of attachment and aggression guide …

A Comparison Of Eastern Gray Squirrel (Sciurus Carolinensis) Nesting Behavior Among Habitats Differing In Anthropogenic Disturbance, Elizabeth Williams

College of Graduate Studies: Theses & Dissertations

Eastern gray squirrels inhabit a large range of heterogeneous habitats and climates, and live with various levels of anthropogenic disturbance. Previous studies have examined this species in unmodified and modified surroundings; however, a comparison of populations between these habitats has yet to be published. Their widespread occurrence coupled with their success in urban areas and the invasive nature of introduced populations, suggests this species is behaviorally flexible. The purpose of this study was to determine the effect of anthropogenic disturbance and development on gray squirrel nesting behavior by comparing variables related to nesting habitat preference among habitats of differing levels …

A Comparison Of Student Performance In Single-Sex Education And Coeducational Settings In Urban Middle Schools, Craig Erico Ogden

College of Graduate Studies: Theses & Dissertations

Since amendments to NCLB in 2004, public schools have not only established single-sex schools, but have also established single-sex classrooms within coeducational schools. Most of these modifications were adopted as a means to provide support to lowachieving students, many of who reside in urban settings. Proponents of single-sex instruction state that mostly African Americans, Hispanics, and females benefit most from this type of instructional setting because single-sex environments help to reduce gender stereotypes students encounter in coeducational settings. Opponents of single-sex instruction believe that accomplishments achieved in single-sex environments can be achieved in coeducational environments if the proper teaching strategies …

Academic Tenure: Defining Scholarship In The Health Professions, Kimberly Mathieu Coulton

College of Graduate Studies: Theses & Dissertations

Higher education institutions in the United States grant academic tenure to junior faculty based on teaching, service, and scholarship. Traditionally, scholarship is defined as original research that is demonstrated by reports of scientific findings, peer-reviewed journal publications and presentations. However, workload issues, insufficient institutional support and ambiguity in tenure guidelines often hinder the scholarly endeavors of university faculty seeking tenure. The roles and responsibilities of faculty in the allied health professions are unique in that they are also involved in the provision of patient care, the development of community partnerships and the task of addressing vital workforce needs. A broader …

Separate But Equal? A Postmodern Analysis Of Educational Structures For Individuals With Disabilities, Donna Manning

College of Graduate Studies: Theses & Dissertations

Although curriculum theorists have sought to examine the subjective practices imposed within the context of schooling in terms of class, gender, and race, the impact of disability as a social category has been absent from the field. In this work, postmodern analysis is applied to the concept of disability in field of education; first, in terms of the nature and effects of the practices educators employ to define normality, and secondly, in the constitution of the students who deviate from the norm as subjects. The techniques and procedures of investigation, surveillance, exclusion, treatment, confinement, and medicalization developed and engaged in …

Density, Shell Use And Species Composition Of Juvenile Fiddler Crabs (Uca Spp.) At Low And High Impact Salt Marshes On Georgia Barrier Islands, Michelle D. Carlson

College of Graduate Studies: Theses & Dissertations

Coastal wetlands offer refuge for juveniles of many species, with protection often coming in the form of dense vegetation. Human impacts have led to a 67% loss of coastal wetlands worldwide in the past 300 years, thus decreasing available refuges. There are no studies that show what affect this has on fiddler crabs (Uca spp.), a key species in salt marsh habitats. The present study looks at how human impacts are affecting juvenile fiddler crab densities, shell use, and species compositions. This study was conducted at 3 low and 3 high impact sites on Tybee and Skidaway Island, Georgia. Six …

Evaluating Restoration Potential Of An Endangered Legume, Baptisia Arachnifera: Shade & Litter Effects On Early Life Stages, Timothy John Estep

College of Graduate Studies: Theses & Dissertations

Baptisia arachnifera, hairy rattleweed, is a federally endangered, herbaceous, legume endemic to Wayne and Brantley Counties in Georgia. The species has declined by 89% in the past 20 years. Therefore I examined the early life stages of the species for weevil predation, fungus infection, and germination; information used to help prevent the species extinction. Seed pods of Baptisia arachnifera from six sites were examined for weevil predation and fungal infestation. Germination was examined under greenhouse conditions. One site had intense weevil predation, fungal infection, and reduced germination compared to other sites. Over 62% of seeds germinated within the greenhouse. To …

The Effects Of Simulation On Junior Level Baccalaureate Nursing Students' Self-Efficacy And Intrinsic Motivation, Michelle E. Dykes

College of Graduate Studies: Theses & Dissertations

Nursing education is experiencing a generational phenomenon with student enrollment spanning three generations. Classrooms cultures are changing today and include some Baby Boomers and large numbers of Generation X, Generation Y, and second-degree seeking students. These culturally diverse groups of students have unique sets of learning characteristics. Given the current challenges of growing student diversity, balancing budgets, and meeting faculty shortages, nursing schools are pressed to find alternative teaching methods that are not only cost and labor saving but also effective and equitable for the diverse student groups. This quantitative, experimental research design study explored the effects of the alternative …

Phytoplankton Ecology In The Skidaway River Estuary, Darren Parris

College of Graduate Studies: Theses & Dissertations

Short-term and seasonal variation in abiotic factors such as salinity, nutrient concentration, and light availability strongly influence total phytoplankton biomass but less is known about their effects on species-level changes due to difficulties associated with identifying and enumerating individual taxa. Understanding taxon-specific shifts is important as species often contribute differently to primary productivity and food web support for higher trophic levels. The goals of this study were to examine changes in overall phytoplankton abundance and community composition following short-term increases in freshwater input (Chapter 1), seasonal variation in abiotic conditions (Chapter 2), and manipulated nutrient concentrations within the Skidaway River …

The George-Anne, Georgia Southern University

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The Inkwell, Armstrong Atlantic State University

The Inkwell

No abstract provided.

Fear And Fascination: A Study Of Thomas Hardy And The New Woman, Anita Sandlin

College of Graduate Studies: Theses & Dissertations

The tragic outcomes of most of his fictional heroines have led many to accuse Thomas Hardy of being a misogynist, harshly punishing women for their open defiance of Victorian social expectations. However, by writing about sexually-charged issues at a time when subjects such as premarital sex, rape, illegitimate children, adultery, and divorce were taboo, Hardy challenged his readers to consider the destructive power caused by hypocrisy and double standards, making many consider him to be among the first feminists. These conflicting perspectives reflect the internal ambiguities of a gifted man torn between wanting to maintain the conservative comfort of the …