Digital Commons Network^™

The Effects Of Cucurbitacin B And Silmitasertib On Metastasis And Itga6 Using The Zebrafish Tumor-Xenograft, Alexandra Griffis

College of Graduate Studies: Theses & Dissertations

Ninety percent of cancer deaths are resultant from the metastasis of cancer cells. When cancer cells translocate through blood vessels or the lymphatic system, they may form tumors outside of their primary site. The processes of metastasis can begin quickly; after onset, metastasis is unforgiving, as it does not participate with the body’s physiological systems in an orderly way. In the past, our lab produced results indicating that a cell adhesion molecule, Integrin Alpha-6, may contribute to cancer cells' ability to metastasize. Integrins mediate interactions between the cell and the Extracellular Matrix (ECM), regulating cell attachment and cell migration. With …

The Relationship Between Academic Advising And Students' Completion Of Corequisite Gateway Courses, Michael P. Moran

College of Graduate Studies: Theses & Dissertations

This bivariate correlational quantitative study sought to determine how variables predicted students’ course outcomes in first-year English and mathematics courses within a corequisite learning support model. Course outcomes were defined dichotomously on a successful completion or unsuccessful completion basis. The participants of this study included those who initially attempted first-year English (n = 2,055) and mathematics (n = 2,843) course(s) in a corequisite learning support model for the first time between Fall 2018 and Spring 2022 and were assigned as advisees to the professional academic advisors in the centralized advising model. The examined predictors were students’ frequency of sessions, length …

Loggerhead Sea Turtle (Caretta Caretta) Nesting Experience, Seasonal Variation, And Hatching Success On A Georgia Barrier Island, Luke Sundquist

College of Graduate Studies: Theses & Dissertations

Loggerhead sea turtles nest commonly on the Georgia barrier islands and serve critical roles in human cultures, coastal economies, and multiple ecosystems. However, their global populations are declining and dependent on conservation efforts and informed management of natural and anthropogenic threats. Nesting offers a unique opportunity to research and protect this valuable marine species in terrestrial habitats. Microsatellite DNA sampling from eggshells can consistently identify nesting females from eggshells, allowing tracking of nesting behaviors for large populations over multiple years. Using this novel technology, we compared maternal investment and nest site-selection between first-time nesting neophytes and experienced remigrants. We sampled …

Middle Savannah River: An A/R/Tographic Ecopedagogical Ethnography Experimenting With Rhizomatic Perspectives, Lisa Augustine-Chizmar

College of Graduate Studies: Theses & Dissertations

This research is an experiment in perspective. Using the four commonplaces (Schwab, 1978), I practiced letting the Savannah River teach me what there is to know about the water, the land, the people, and the other entities that depend on ki through artistic, ethnographic, and ecopedagogical lenses. The ethnographic findings describe the social actors that depend on ki and give a voice to the River. The a/r/tographic findings display the River on a canvas map through two hundred years using paint, clay, photography, video, abstract acrylics, and fabric. Together, these methods contribute to a unique ecopedagogical journey. This word cloud …

Investigating Salinity Intrusion Effects On Sapelo Island, Georgia Using Benthic Macroinvertebrate Bioindicators, Raymond Paul Kidder Ii

College of Graduate Studies: Theses & Dissertations

Coastal wetlands are threatened by the compounding effects of sea level rise and historical land modification. Historically, much of Sapelo Island, Georgia was deforested and drained using a series of ditches and canals to create arable land fit for agriculture and to provide drainage to the inhabited parts of the island. Today, this network of artificial channels is believed to be facilitating the movement of saltwater from the nearby estuary into freshwater areas on the interior of the island. This study aimed to better understand the frequency and magnitude of salinity intrusion events along with their resulting impacts to the …

Promoting The Positive: A Case Study Of The Influence Of School Climate On One Turnaround School From 2016-2022, Cynthia Gunner

College of Graduate Studies: Theses & Dissertations

Schools across the country are finding various means to address the social realities that often exist in high poverty schools. School climate is one of those social realities. While there is research related to school climate in high poverty schools, there are limited case studies related to this subject. This qualitative case study examined how one elementary school was transformed by creating a positive school climate between 2016-2022. This study also explored the impact that the pandemic and subsequent school lockdown had on the newly established school climate. Findings from this study indicated that PF Elementary School established a positive …

Investigation Of Additives And Ingredients Of Bio-Resin For Visible Wavelength Laser-Induced Polymerization, Patrick Riggs

College of Graduate Studies: Theses & Dissertations

Optical 3D printing is a branch of Additive manufacturing (AM) that utilizes low-waste production leading to efficient and rapid prototyping. Currently, this method of AM is associated with mainly petroleum-based resins. Bio-resin polymerization is an emerging research area for finding replacements for petroleum-based resins, but curing the resin with laser energy is not normally a practical use case. Current optical 3D printing uses lasers to cure liquid resins to form solid 3D objects in a layer-by-layer process which is time consuming, defect prone, and a leading limiting factor for high volume production; so, finding a way to incorporate bio-resin into …

Blockchain Securities Issues: Decentralized Identity System With Key Management Perspective, Olalekan O. Adaramola

College of Graduate Studies: Theses & Dissertations

Blockchain was created many years ago to solve the problems of data transfer Integrity, several years later the issues persist. Blockchain securities are one of the most important considerations to be investigated, and data integrity is about ensuring the accuracy and validity of messages such that when they are read, they are the same as when they were first written. It is of the opinion that passing information across from one person to another cannot be the same as it was first said at the onset. Our work investigated Blockchain security issues, studying Integrity emanating from transactions across the blocks …

Petrological And Geochemical Evaluation Of Rare-Earth Element Potential In The Sparta Granite Complex, Max J. Eshbaugh

Honors College Theses

Rare earth elements (REEs) are important resources with applications in the electronics, renewable energy, and automotive industries. REEs may be concentrated in the residual weathered portion of igneous parent rocks, typically granites. These residual deposits are mined in southeast Asia, but analogous climatic and geologic conditions suggest the existence of economically viable REE residual deposits in the southeastern United States (U.S.). The Sparta Granite Complex in east-central Georgia is a granitoid complex emplaced at the end of the Alleghanian orogeny, forming a suture between the Savannah River and Milledgeville terranes. Petrologic and geochemical assessments of the Sparta Granite and overlying …

Examining The Oxidative Stress Effects In Rats Exposed To 2-Aminoanthracene In Utero And High Fat Diet Three Months After, Brianna A. Lanoix

Honors College Theses

Polycyclic aromatic hydrocarbons are organic compounds that are created synthetically or found in partially burned oil, gasoline, and coal. 2-aminoanthracene (2AA) is a common example of a PAH and can affect lipid and carbohydrate metabolism and resulting in inflammatory problems and oxidative stress. The objective of the research project is to investigate oxidative stress in relation to diabetes in rats exposed to 2AA in utero and a high fat diet later in life. Pregnant dams were separated into treatment groups based on their dosages of 2AA; 0 mg/kg (control), 50 mg/kg (low), 100 mg/kg (high). During the gestation -postpartum period, …

Using Historical Thinking Strategies For Improving Elementary Students’ Content Knowledge And Attitudes Towards Social Studies, Lydia Burnett, Joshua Cuevas Dr.

Georgia Educational Researcher

Instructional time spent on elementary social studies is often marginalized due to the emphasis placed on other content areas. Therefore, social studies teachers must employ meaningful instructional strategies that will engage students while promoting content acquisition. This quasi-experimental study responds to this challenge by guiding a sample of 44 fifth grade students to use the historical thinking skills of sourcing, contextualizing, and corroborating that encourage engagement with a variety of primary sources through the lens of Jerome Bruner’s learning theories. The control group used traditional instructional methods including close-note taking, vocabulary review, and independent reading from social studies texts. Both …

Eagle Accountant - 2023, Georgia Southern University

Eagle Accountant

• Accounting Advisory Council
• Advisory Council Spotlight
• Accreditation & Rankings
• Commencement 2023
• Cover Story: Ironman
• Student Spotlight: Soaring to New Heights
• Student Spotlight: Reconciling Expectations with Reality
• Accounting Day 2023
• Student Organizations & Activities
• Junior Achievement
• Faculty Awards
• Faculty Research, Publications, & Service
• Alumni Spotlight: An Eagle on Pennsylvania Avenue
• Alumni Notes, Awards, & Recognition
• In Memoriam

2023 Fall Commencement, Georgia Southern University

Commencement Programs

No abstract provided.

Eagle Executive Magazine, Georgia Southern University

College of Business: News & Publications

• From the Desk of Dean Amason
• Eagles on Pennsylvania Avenue
• Professional Development Day
• Feature: Internships Plant the Seeds for Career Success
• Student Org Spotlight
• Alumni
• Young Alumni Board

Reflection On Best Practices In Designing Online Middle Level Learning, Holly J. Thornton

Current Issues in Middle Level Education

An increase in online learning during the pandemic has led to new thinking about online instruction that will last far beyond the pandemic. The hurried nature of instructional design as the pandemic shifted teaching and learning from the classroom to the computer may have neglected the need to design lessons using best practices online instead of focusing on content delivery and grading. Practices that are part of successful middle level education including cultivating depth of student understanding, developmental responsiveness, social emotional learning and differentiation to meet young adolescent student needs may have been neglected in pandemic online lesson design. This …

Examining Teaching And Learning Environments Among Kentucky Schools To Watch And Non-Schools To Watch Schools Using Tell Survey Data, Michael Dicicco, Ryan Alverson

Current Issues in Middle Level Education

In 2017, the state of Kentucky distributed the Teaching, Empowerment, Leading, and Learning (TELL) survey to gain an understating of the learning environments in Kentucky schools. Many of the items on the TELL survey addressed key components of the School to Watch criteria and rubric. Researchers were interested in the teaching and learning conditions in Kentucky middle schools that contributed to successful school environments as defined by the Schools to Watch criteria, and to use results from the TELL survey to see what high scoring schools were doing well according to the teachers and principals that completed the survey. Researchers …

On Kernel-Based Estimator Of Odds Ratio Using Different Stratified Sampling Schemes, Abbas Eftekharian, Hani Samawi, Haresh Rochani

Biostatistics, Epidemiology & Environmental Health Sciences: Faculty Publications

The kernel-based estimator of Cochran Mantel-Haenszel odds ratio based on stratified simple and ranked set sampling is proposed. The expectation and variance of the estimator are analytically obtained. Using a simulation study, the estimator based on stratified ranked set sampling is more efficient than its counterpart based on stratified simple random sampling. Finally, the estimator's performance is investigated by using base deficit data.

Nanoparticle Conjugated Photosensitizer For Targeted Photodynamic Inactivation Of Cancer Cells, Symone D. Crowder

Honors College Theses

Photodynamic therapy (PDT) is considered to be a potential replacement for traditional methods of chemotherapy. It includes the administration of photosensitizing agents (PS), which generate reactive oxygen species (ROS) upon excitation at a specific wavelength. With new outlooks and techniques, cancer research is advancing each day. It has allowed the progress of several theranostic drug delivery systems (DDS) exploring the area of nanomedicine.2 In the present work, a Rhodamine derivative, Rhodamine 6G (R6G) was used as the PS. In general, rhodamine compounds undergo cytotoxic reactions on photoexcitation by electron transfer reactions with folic acid within cells, making them a favorable …

College Of Engineering News, Georgia Southern University

College of Engineering & Computing: News & Publications (2010-2023)

• From MechE to Aerojet Rocketdyne: an Eagle finds her wings

College Of Engineering News, Georgia Southern University

College of Engineering & Computing: News & Publications (2010-2023)

• From MechE to Aerojet Rocketdyne: an Eagle Finds her Wings

Newsroom, Georgia Southern University

Newsroom (2006-2023)

• Approximately 2,100 Degrees Conferred During Georgia Southern’s 2022 Fall Commencement Ceremonies
• Graduating Student had ‘Wild’ Time at Georgia Southern
• Educator Turned Soldier: Georgia Southern ROTC Graduate Commissions as Officer in National Guard After Returning for MBA Degree
• Nontraditional Student Returns to Georgia Southern University to Chart New Career Path

Newsroom, Georgia Southern University

Newsroom (2006-2023)

• A Graduate of Firsts: Honors College Double Major and Navy Intelligence Analyst Emma Williams Crosses New Frontiers
• ‘Instead of Retiring, I’m Refiring,’ Says Public Health Advocate Who Earns Georgia Southern Doctoral Degree this Week
• From Georgia Southern to Aerojet Rocketdyne: December Graduate Finds Her Wings
• Georgia Southern Graduate Finds Career at Top Cybersecurity Consulting Firm
• Aspiring Lawyer Becomes Georgia Southern Graduate at 17
• ‘It’s Like Something from a Movie’ for a Pair of Graduating Eagle Singers

Georgia Southern University Fact Book, Georgia Southern University

Georgia Southern Fact Books (1976-2022)

No abstract provided.

The George-Anne Daily, Georgia Southern University

George-Anne Media Group: Newsletters & Magazines

No abstract provided.

A Qualitative Multi-Disciplinary Analysis Of Employers’ Technology Competency Perceptions For Graduates Readiness To The Workforce, Marcel Maghiar, Christopher M. Brown

Civil Engineering & Construction: Faculty Publications

To fully prepare college graduates to function competently and productively in their career, it is important to examine employers’ views of technology competency and graduates’ readiness. Using a qualitative approach by interviewing employers in South-eastern United States across a range of fields, the authors describe the major functions and dimensions of technology competency, compare similarities and differences across the disciplines, and integrate the results to inform theory and pedagogy. The main purpose of this research is to investigate how well new graduates from selected disciplines can transfer technological skills, how they learned and/or used these skills during their program of …

A Bootstrap Method For A Multiple-Imputation Variance Estimator In Survey Sampling, Lili Yu, Yichuan Zhao

Biostatistics, Epidemiology & Environmental Health Sciences: Faculty Publications

Rubin’s variance estimator of the multiple imputation estimator for a domain mean is not asymptotically unbiased. Kim et al. derived the closed-form bias for Rubin’s variance estimator. In addition, they proposed an asymptotically unbiased variance estimator for the multiple imputation estimator when the imputed values can be written as a linear function of the observed values. However, this needs the assumption that the covariance of the imputed values in the same imputed dataset is twice that in the different imputed datasets. In this study, we proposed a bootstrap variance estimator that does not need this assumption. Both theoretical argument and …

Pandemic Fatigue Impedes Mitigation Of Covid-19 In Hong Kong, Zhanwei Du, Lin Wang, Songwei Shan, Dickson Lam, Tim K. Tsang, Jingyi Xiao, Huizhi Gao, Bingyi Yang, Sheikh Taslim Ali, Sen Pei, Isaac Chun-Hai Fung, Eric H. Y. Lau, Qiuyan Liao, Peng Wu, Lauren Ancel Meyers, Gabriel M. Leung, Benjamin Cowling

Biostatistics, Epidemiology & Environmental Health Sciences: Faculty Publications

Hong Kong has implemented stringent public health and social measures (PHSMs) to curb each of the four COVID-19 epidemic waves since January 2020. The third wave between July and September 2020 was brought under control within 2 m, while the fourth wave starting from the end of October 2020 has taken longer to bring under control and lasted at least 5 mo. Here, we report the pandemic fatigue as one of the potential reasons for the reduced impact of PHSMs on transmission in the fourth wave. We contacted either 500 or 1,000 local residents through weekly random-digit dialing of landlines …

Association Between The Health Belief Model, Exercise, And Nutrition Behaviors During The Covid-19 Pandemic, Keagan Kiely, Bill Mase, Andrew R. Hansen, Jessica S. Schwind

Biostatistics, Epidemiology & Environmental Health Sciences: Faculty Publications

Introduction: The COVID-19 pandemic has affected our nation’s health further than the infection it causes. Physical activity levels and dietary intake have suffered while individuals grapple with the changes in behavior to reduce viral transmission. With unique nuances regarding the access to physical activity and nutrition during the pandemic, the constructs of Health Belief Model (HBM) may present themselves differently in nutrition and exercise behaviors compared to precautions implemented to reduce viral transmission studied in previous research. The purpose of this study was to investigate the extent of exercise and nutritional behavior change during the COVID-19 pandemic and explain the …

Messages From The Provost, Georgia Southern University

Messages from the Provost

• A Message from the Provost

Blank Spaces: An Exploration Of Memory And Nostalgia Through Mixed Media, Julianna V. Tillman

Honors College Theses

Blank Spaces explores the way childhood nostalgia manifests in the physical world through the creation of mixed media pieces. The experimentation with different mediums in my work, such as painting, ceramics, and animation, is emblematic of childhood creative play. These mixed media artworks showcase how memories recalled from the past can influence our interpretation of the present. The familial connection to family and culture, represented through manipulated old family photographs and imaginary renderings of stories, blends representational imagery with fantasy; my art examines the movement of those memories in the “blank spaces” of the mind. The thesis adds to the …