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Articles 541 - 570 of 13603

Full-Text Articles in Entire DC Network

Mass Cytometry Workflow To Achieve High-Dimensional Immunophenotyping In Resource-Limited Or Decentralized Environments, Natalie Smith, Michael Cohen, Lauren Tracey, Julie Alipaz, Christina Loh, David King, Neha Pulyani, Rebecca Auzins, Elin Gray, Sandra Taylor, Rajat Rai, Steven Kao, Barbara Fazekas De St Groth, Helen Mcguire Mar 2026

Mass Cytometry Workflow To Achieve High-Dimensional Immunophenotyping In Resource-Limited Or Decentralized Environments, Natalie Smith, Michael Cohen, Lauren Tracey, Julie Alipaz, Christina Loh, David King, Neha Pulyani, Rebecca Auzins, Elin Gray, Sandra Taylor, Rajat Rai, Steven Kao, Barbara Fazekas De St Groth, Helen Mcguire

Research outputs 2022 to 2026

Globally, regional and remote communities are burdened by both an increased prevalence and worse prognosis of many infectious and chronic diseases. However, largely owing to logistical challenges, these communities are under-represented in clinical trials and research studies. As individuals from rural communities experience unique environmental exposures and risk factors for disease, immune phenotyping data collected from metropolitan populations may not be broadly generalizable. To address this, we present a workflow that enables the inclusion of resource-limited sites in high-parameter mass cytometry studies. In this approach, whole blood (WB) or peripheral blood mononuclear cells (PBMCs) are collected, stained fresh for surface …

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Vibostolimab Coformulated With Pembrolizumab Versus Pembrolizumab Alone As Adjuvant Therapy For High-Risk Stage Iib–Iv Melanoma (Keyvibe-010): A Randomised, Double-Blind, Phase 3 Study, Reinhard Dummer, Jun Guo, Jason J. Luke, Matteo S. Carlino, Dirk Schadendorf, Muhammad A. Khattak, Axel Hauschild, Paolo A. Ascierto, Yu Chen, Sang Joon Shin, Piotr Rutkowski, Zhiguo Luo, Jing Chen, Gareth Rivalland, Corlia Coetzee, Antoni Ribas, Karmele Mujika, Gal Markel, Rodrigo U. Villarroel, Omer Dizdar, Christian Caglevic, Dmitri Grebennik, Kevin Donovan, Clemens Krepler, Georgina V. Long Mar 2026

Vibostolimab Coformulated With Pembrolizumab Versus Pembrolizumab Alone As Adjuvant Therapy For High-Risk Stage Iib–Iv Melanoma (Keyvibe-010): A Randomised, Double-Blind, Phase 3 Study, Reinhard Dummer, Jun Guo, Jason J. Luke, Matteo S. Carlino, Dirk Schadendorf, Muhammad A. Khattak, Axel Hauschild, Paolo A. Ascierto, Yu Chen, Sang Joon Shin, Piotr Rutkowski, Zhiguo Luo, Jing Chen, Gareth Rivalland, Corlia Coetzee, Antoni Ribas, Karmele Mujika, Gal Markel, Rodrigo U. Villarroel, Omer Dizdar, Christian Caglevic, Dmitri Grebennik, Kevin Donovan, Clemens Krepler, Georgina V. Long

Research outputs 2022 to 2026

Background Combination therapy with vibostolimab plus pembrolizumab has previously shown promising antitumor activity in melanoma. We aimed to evaluate the efficacy and safety of vibostolimab coformulated with pembrolizumab as adjuvant therapy for high-risk resected melanoma. Methods This randomised, double-blind, phase 3 study was done at 205 global sites (hospitals and cancer centres). Participants aged 12 years or older with surgically resected, stage IIB–IV cutaneous melanoma per the American Joint Committee on Cancer Cancer Staging Manual 2017 (8th edition), with no evidence of metastatic disease after resection, were randomly assigned (1:1) to receive vibostolimab 200 mg coformulated with pembrolizumab 200 mg …

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Assessment Of Rotator Cuff External Rotation: Isometric Vs. Isotonic Testing Modes, Luca Maestroni, Filippo Beretta, Fabio Civera, Paolo Artina, Marco Cuniberti, Francesco Bettariga, Anthony Turner Mar 2026

Assessment Of Rotator Cuff External Rotation: Isometric Vs. Isotonic Testing Modes, Luca Maestroni, Filippo Beretta, Fabio Civera, Paolo Artina, Marco Cuniberti, Francesco Bettariga, Anthony Turner

Research outputs 2022 to 2026

Objectives: To assess intra-session reliability of isometric and isotonic shoulder external rotation (ER) strength tests and to compare their outcomes. Methods: Thirty-eight healthy subjects (19 females; 19 males; 25.7 ± 6.0 years; 175 ± 9 cm; 70.3 ± 11.4 kg) completed a shoulder ER strength assessment including Prone and Standing ER Isometric tests and Seated 5 repetition maximum (RM) ER tests. Normality was checked with the Shapiro–Wilk test. Reliability was assessed using the CV and ICC (3, k, 95% CI). Linear mixed models examined sex and dominance effects. Correlations and multiple regression tested associations between tests (p < 0.05). Results: All tests performed displayed “excellent” reliability scores (CV from 1.9 to 3.1% and ICC from 0.970 to 0.994). No significant effect of dominance was observed in any strength test. Males showed significantly higher values than females in both Prone (3.8% higher, p < 0.001) and Standing (2.7% higher, p = 0.003) isometric ER strength tests. Prone and Standing isometric tests were moderately correlated (r = 0.62, 95% CI [0.46, 0.74], p < 0.001). A regression model explained 52.4% of the variance in Seated 5 RM ER strength (R2 = 0.524, …

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Digital Pain Assessment: Patient And Family Perspectives, Rosemary Saunders, Kate Crookes, Kaoru Nosaka, Olivia Gallagher, Jeff Hughes, Caroline Bulsara, Max K. Bulsara, Seng Giap Marcus Ang, Beverley Ewens, Sue Haydon, Karla Seaman, Renée Graham, Debra Scaini, Karen Gullick, Michelle Gay, Christopher Etherton-Beer, Renée Graham Mar 2026

Digital Pain Assessment: Patient And Family Perspectives, Rosemary Saunders, Kate Crookes, Kaoru Nosaka, Olivia Gallagher, Jeff Hughes, Caroline Bulsara, Max K. Bulsara, Seng Giap Marcus Ang, Beverley Ewens, Sue Haydon, Karla Seaman, Renée Graham, Debra Scaini, Karen Gullick, Michelle Gay, Christopher Etherton-Beer, Renée Graham

Research outputs 2022 to 2026

Background/Objectives: Pain is a common symptom for hospitalised older adults. Pain is not always adequately assessed, which can lead to inadequate pain management and adverse patient outcomes. Thus, new technology-driven pain assessment tools have been developed; however, little is known about patients’ and families’ experiences of nurses using them in acute care. This study aimed to explore the perspectives of older adult inpatients and their families’ regarding nurses’ use of the digital technology-driven pain assessment application PainChek® Universal. Methods: A survey was undertaken as part of a stakeholder evaluation of a randomised control trial exploring the effectiveness of nurse-led …

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Graph Convolution Neural Network And Deep Q-Network Optimization-Based Intrusion Detection With Explainability Analysis, Kelvin Mwiga, Mussa Dida, Leandros Maglaras, Ahmad Mohsin, Helge Janicke, Iqbal H. Sarker Mar 2026

Graph Convolution Neural Network And Deep Q-Network Optimization-Based Intrusion Detection With Explainability Analysis, Kelvin Mwiga, Mussa Dida, Leandros Maglaras, Ahmad Mohsin, Helge Janicke, Iqbal H. Sarker

Research outputs 2022 to 2026

As networks expand in size and complexity, coupled with an exponential increase in intrusions on network and IoT systems, this leads to traditional models failing to capture increasingly intricate correlations among network components accurately. Graph Convolution Networks (GCNs) have recently acquired prominence for their capacity to represent nodes, edges, or entire graphs by aggregating information from adjacent nodes. However, the correlations between nodes and their neighbours, as well as related edges, differ. Assigning higher weights to nodes and edges with high similarity improves model accuracy and expressiveness. In this paper, we propose the GCN-DQN model, which integrates GCN with a …

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Machine Learning-Based Upscaling Of Rock Permeability From Pore Scale To Core Scale: Effect Of Training Dataset Size And Sub-Core Volumes, Yaotian Guo, Fei Jiang, Takeshi Tsuji, Yoshitake Kato, Mai Shimokawara, Lionel Esteban, Mojtaba Seyyedi, Marina Pervukhina, Maxim Lebedev, Ryuta Kitamura Mar 2026

Machine Learning-Based Upscaling Of Rock Permeability From Pore Scale To Core Scale: Effect Of Training Dataset Size And Sub-Core Volumes, Yaotian Guo, Fei Jiang, Takeshi Tsuji, Yoshitake Kato, Mai Shimokawara, Lionel Esteban, Mojtaba Seyyedi, Marina Pervukhina, Maxim Lebedev, Ryuta Kitamura

Research outputs 2022 to 2026

Permeability characterizes the capacity of porous formations to conduct fluids, thereby governing the performance of carbon capture, utilization, and storage (CCUS), hydrocarbon extraction, and subsurface energy storage. A reliable assessment of rock permeability is therefore essential for these applications. Direct estimation of permeability from low-resolution CT images of large rock samples offers a rapid approach to obtain permeability data. However, the limited resolution fails to capture detailed pore-scale structural features, resulting in low prediction accuracy. To address this limitation, we propose a convolutional neural network (CNN)-based upscaling method that integrates high-precision pore-scale permeability information into core-scale, low-resolution CT images. In …

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Leveraging Generative Ai For Project Management: The Role Of Mindfulness And Job Crafting, Keyao Li, Fangfang Zhang, Laurie Hughes, Mark A. Griffin Mar 2026

Leveraging Generative Ai For Project Management: The Role Of Mindfulness And Job Crafting, Keyao Li, Fangfang Zhang, Laurie Hughes, Mark A. Griffin

Research outputs 2022 to 2026

The integration of generative artificial intelligence (GenAI) holds great potential to transform the project management profession, which can bring both substantial benefits and significant disruption. This study argues that effective GenAI adoption requires not only technical skills but also mindfulness to navigate its complexities and challenges. This study explores how mindfulness supports project managers in leveraging GenAI technologies to innovate work practices. We argue that project managers with higher mindfulness levels tend to be more open, attentive, and creative in crafting their immediate work environment. This, in turn, encourages project managers to explore how GenAI can optimise workflows, and ultimately …

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Psychosocial Determinants Of Hand Hygiene Practices Among Children And Adolescents Living With Hiv In The Northern City Of Malawi, Balwani Chingatichifwe Mbakaya, Maggie Zgambo, Richard Moyo, Paul Uchizi Kaseka, Obed Nkhata, Fatch Kalembo Feb 2026

Psychosocial Determinants Of Hand Hygiene Practices Among Children And Adolescents Living With Hiv In The Northern City Of Malawi, Balwani Chingatichifwe Mbakaya, Maggie Zgambo, Richard Moyo, Paul Uchizi Kaseka, Obed Nkhata, Fatch Kalembo

Research outputs 2022 to 2026

Background: The common cause of death in HIV and AIDS patients are opportunistic infections such as diarrhoea, acute respiratory infections, and skin conditions. Many of these infections are spread through contaminated hands. Therefore, this study aimed at exploring hand hygiene practices among HIV positive children and adolescents in Mzuzu City, Malawi. Methodology: A cross-sectional study was used to collect data from children and adolescents living with HIV (aged between 9 and 18 years) WHO were attending teen clubs in Mzuzu City. Data were analysed using Stata 17. Chi-Square and logistic regression analysis were used to examine the association among multiple …

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Comprehensive Review Of Lithium Extraction Processes With Economic And Environmental Analysis, Shayan Abrishami, Maryam Gonbadi, Yasaman Boroumand, Mahsa Golmohammadi, Mehdi Narimani, Amin Sarmadi, Chase Matthews, Humberto Estay, Mehdi Khiadani, Amir Razmjou Feb 2026

Comprehensive Review Of Lithium Extraction Processes With Economic And Environmental Analysis, Shayan Abrishami, Maryam Gonbadi, Yasaman Boroumand, Mahsa Golmohammadi, Mehdi Narimani, Amin Sarmadi, Chase Matthews, Humberto Estay, Mehdi Khiadani, Amir Razmjou

Research outputs 2022 to 2026

The growing need for lithium, primarily driven by the expanding electric car market and increasing energy storage requirements, has created a significant demand for sustainable and efficient lithium extraction techniques. This comprehensive review examines the current state and prospects of lithium extraction technologies from both hard-rock and brine sources, offering an enviro-economic perspective on various production methods. While several reviews have attempted to cover lithium extraction in various aspects, our work specifically focuses on the processes of lithium extraction from different sources. We systematically evaluate traditional hard-rock extraction processes, including sulfating, alkali, chlorination, and carbonizing methods, detailing their mechanisms, efficiencies, …

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Remnant Cholesterol And Atherosclerotic Cardiovascular Disease Risk In Populations With Different Low-Density Lipoprotein Cholesterol Elevations: A Prospective Cohort Study, Hong Zheng, Guanlin Chen, Zhenyu Huo, Yulong Lan, Yuxian Wang, Peng Fu, Weiqiang Wu, Haixiang Zheng, Kuangyi Wu, Zegui Huang, Dan Wu, Shouling Wu, Youren Chen Feb 2026

Remnant Cholesterol And Atherosclerotic Cardiovascular Disease Risk In Populations With Different Low-Density Lipoprotein Cholesterol Elevations: A Prospective Cohort Study, Hong Zheng, Guanlin Chen, Zhenyu Huo, Yulong Lan, Yuxian Wang, Peng Fu, Weiqiang Wu, Haixiang Zheng, Kuangyi Wu, Zegui Huang, Dan Wu, Shouling Wu, Youren Chen

Research outputs 2022 to 2026

Background: Low-density lipoprotein cholesterol (LDL-C) and remnant cholesterol (RC) are risk factors for atherosclerotic cardiovascular disease (ASCVD). However, the extent to which differences in RC levels affect ASCVD risk in populations with varying degrees of LDL-C elevation remains unclear. This study aimed to investigate whether RC can provide additional risk stratification value across different sexes, ages, and elevated LDL-C statuses. Methods: This study included 12 743 elevated LDL-C participants (LDL-C ≥3.4 mmol/L) and 50 073 age- and sex-matched non-elevated LDL-C controls from the Kailuan Study. Elevated LDL-C participants were categorized by RC levels into <0.5, 0.5 to <1.0, and ≥1.0 mmol/L subgroups. Kaplan-Meier curves and Cox proportional hazards models were used to assess the relationship between RC levels and ASCVD risk across different sexes, ages, and high LDL-C statuses. Results: During a median follow-up of 12.8 years, 1686 elevated LDL-C participants (13.2%) and 5252 non-elevated LDL-C participants (10.5%) developed ASCVD. In the borderline-high LDL-C group (3.4 ≤ LDL-C < 4.1 mmol/L), those with the lowest RC levels showed no significant risk difference compared with controls (hazard ratio [HR], 1.03 [95% CI, 0.93-1.13]), and this pattern remained consistent across different sexes and ages. In contrast, in the high LDL-C group (LDL-C ≥4.1 mmol/L), even when RC was at the lowest level, ASCVD risk remained significantly higher than that of controls (HR, 1.20 [95% CI, 1.02-1.41]). CONCLUSIONS: In the borderline-high LDL-C population, those with the lowest RC levels showed no significant risk difference compared with controls, and this pattern remained consistent across different sexes and age subgroups. In the high LDL-C population, even when RC was at the lowest level, ASCVD risk remained significantly higher than that of controls.

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Emerging Trends In Photocatalyst-Based Metal-Organic Frameworks For Pfas Degradation, Ahmad Najafidoust, Roham Ghanbari, Javad Farahbakhsh, Ratish Permala, Stefan Iglauer, Masoumeh Zargar Feb 2026

Emerging Trends In Photocatalyst-Based Metal-Organic Frameworks For Pfas Degradation, Ahmad Najafidoust, Roham Ghanbari, Javad Farahbakhsh, Ratish Permala, Stefan Iglauer, Masoumeh Zargar

Research outputs 2022 to 2026

Per- and polyfluoroalkyl substances (PFAS) are highly persistent pollutants in the environment that pose significant health hazards due to their strong chemical resilience and widespread industrial use. Traditional treatment techniques, such as adsorption and reverse osmosis, often struggle with drawbacks like high energy requirements and limited effectiveness against both short- and long-chain PFAS compounds. Among the innovative degradation methods, photocatalysis has gained attention as a viable solution, especially when coupled with metal-organic frameworks (MOFs). MOFs are particularly suited for this purpose due to their high surface area, customizable structures, and superior light absorption properties. This review highlights the latest developments …

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Perceptions Of Ischaemic Heart Disease Risk Among Indian Migrants In Australia: A Qualitative Study, Kunwar Kaur, Ma'en Zaid Abu-Qamar, Amineh Rashidi, Nilufeur Mckay, Rosemary Saunders Feb 2026

Perceptions Of Ischaemic Heart Disease Risk Among Indian Migrants In Australia: A Qualitative Study, Kunwar Kaur, Ma'en Zaid Abu-Qamar, Amineh Rashidi, Nilufeur Mckay, Rosemary Saunders

Research outputs 2022 to 2026

Background: Ischaemic heart disease (IHD) is a global health issue, with people of Indian origin facing earlier onset and more severe cases, leading to higher mortality at younger ages compared to Western countries. Indian migrants maintain similar risks post-migration. Managing modifiable risk factors and improving risk knowledge and health-seeking behaviours are essential, but research on IHD risk perceptions among Indian migrants is limited. Aim: This study explores how first-generation Indian migrants perceive their IHD risk and the factors influencing these perceptions. Methods: As a component of a mixed- method study, a qualitative descriptive study design was employed to examine study …

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Immediate Skin-To-Skin Contact At Very Preterm Birth And Effect On Infant Socio-Emotional Stress Response And Mother–Infant Cortisol Co-Regulation: Secondary Outcomes From The Randomised Clinical Immediate Parent-Infant Skin-To-Skin Study (Ipistoss), Karoline Lode-Kolz, Siri Lillieskold, Hanne Brit Hetland, Eleonora Mascheroni, Stina Klemming, Hanne Pike, Agnes Linner, Nils J. Bergman, Bjorn Westrup, Ulrika Ådén, Evalotte Morelius, Rosario Montirosso, Wibke Jonas, Siren Rettedal Feb 2026

Immediate Skin-To-Skin Contact At Very Preterm Birth And Effect On Infant Socio-Emotional Stress Response And Mother–Infant Cortisol Co-Regulation: Secondary Outcomes From The Randomised Clinical Immediate Parent-Infant Skin-To-Skin Study (Ipistoss), Karoline Lode-Kolz, Siri Lillieskold, Hanne Brit Hetland, Eleonora Mascheroni, Stina Klemming, Hanne Pike, Agnes Linner, Nils J. Bergman, Bjorn Westrup, Ulrika Ådén, Evalotte Morelius, Rosario Montirosso, Wibke Jonas, Siren Rettedal

Research outputs 2022 to 2026

Objective To explore the effects of immediate parent–infant skin-to-skin contact (iSSC) at very preterm birth on maternal–infant behavioural responses and hypothalamic–pituitary–adrenal (HPA) axis reactivity to age-appropriate socio-emotional stress at 4months corrected age. Design Two secondary outcomes from a multicentre randomised controlled trial with two non-blinded parallel groups. Setting Three Scandinavian neonatal intensive care units, level 2 and level 3. Participants 91 infants born at gestational age 28+0to 32+6 from April 2018 to June 2021. Singletons and twins with a second caregiver present were included, regardless of mode of birth. Higher-order births, infants with congenital infections and major malformations were excluded. …

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Humanitarian Hospitality: A Framework For Ethical Encounters In Crisis Tourism, Georges El Hajal, Rodney Westerlaken, Erwin Losekoot Feb 2026

Humanitarian Hospitality: A Framework For Ethical Encounters In Crisis Tourism, Georges El Hajal, Rodney Westerlaken, Erwin Losekoot

Research outputs 2022 to 2026

This paper introduces humanitarian hospitality as a conceptual framework for understanding relational ethics and care practices in crisis-affected tourism. While volunteer tourism, disaster recovery travel, and solidarity-based travel bring individuals into crisis-affected destinations, the hospitality that unfolds in these non-commercial encounters remains under-theorised. Drawing on philosophical perspectives and exploratory qualitative insights from 145 Red Cross and Red Crescent volunteers and aid workers, the study examines how emotional labour, ethical care, and informal hosting are enacted in contexts of conflict and displacement. The findings both parallel and complicate conventional host–guest dynamics, highlighting the ethical and emotional complexities of providing care under …

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Increasing Phytochemical-Rich Foods And Lactobacillus Probiotics In Men With Low-Risk Prostate Cancer – A Randomised, Double-Blind, Placebo-Controlled Trial, Robert J. Thomas, Stacey A. Kenfield, Madeleine Williams, Robert U. Newton, Jeffrey Aldous, Anita Mitra, Zahoor Fazili Feb 2026

Increasing Phytochemical-Rich Foods And Lactobacillus Probiotics In Men With Low-Risk Prostate Cancer – A Randomised, Double-Blind, Placebo-Controlled Trial, Robert J. Thomas, Stacey A. Kenfield, Madeleine Williams, Robert U. Newton, Jeffrey Aldous, Anita Mitra, Zahoor Fazili

Research outputs 2022 to 2026

Men on active surveillance (AS), with prostate cancer, are very interested in dietary strategies that could improve their symptoms and help prevent progression of their disease. In this real-world trial involving 208 men, intake of phytochemical-rich food capsules helped slow prostate-specific antigen (PSA) progression significantly, and improved urinary symptoms and erectile function. What was novel about this study was that men randomised to take an additional blend of five Lactobacillus probiotics had a further three-fold slowing of PSA progression as well as reduction of inflammation. Currently, nearly 50% of men opt out of AS within 5 yr. If confirmed with …

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Plasma Biomarker Progression Across The Alzheimer's Disease Amyloid Beta And Tau Positron Emission Tomography Trajectories, Rodrigo Cánovas, Christopher J. Fowler, Azadeh Feizpour, Vincent Dóre, Pierrick Bourgeat, Ziad S. Saad, Gallen Triana-Baltzer, Hartmuth C. Kolb, Manu Vandijck, Gwendlyn Kollmorgen, Clara Quijano-Rubio, Jurgen Fripp, Simon Laws, Anthony W. Bannon, Kaj Blennow, Henrik Zetterberg, Stephanie Rainey-Smith, Sulantha Mathotaarachchi, Christopher C. Rowe, Colin L. Masters, James D. Doecke Feb 2026

Plasma Biomarker Progression Across The Alzheimer's Disease Amyloid Beta And Tau Positron Emission Tomography Trajectories, Rodrigo Cánovas, Christopher J. Fowler, Azadeh Feizpour, Vincent Dóre, Pierrick Bourgeat, Ziad S. Saad, Gallen Triana-Baltzer, Hartmuth C. Kolb, Manu Vandijck, Gwendlyn Kollmorgen, Clara Quijano-Rubio, Jurgen Fripp, Simon Laws, Anthony W. Bannon, Kaj Blennow, Henrik Zetterberg, Stephanie Rainey-Smith, Sulantha Mathotaarachchi, Christopher C. Rowe, Colin L. Masters, James D. Doecke

Research outputs 2022 to 2026

Introduction: With increased uptake in disease-modifying treatments for amyloid beta (Aβ) removal, it is important to measure performance of highly sensitive plasma biomarkers to detect the presence of Aβ and tau in cognitively impaired populations. Methods: In this study, we investigated a large set of plasma biomarkers for their capability to predict Aβ and tau positron emission tomography (PET) and their association with increasing Aβ and tau burden. RESULTS: From the biomarkers assessed, tau phosphorylated at threonine 217 (pTau217) showed the largest increases across the full range of Aβ and tau levels. Furthermore, pTau217/Aβ42 had the smallest proportion of participants …

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Taurine Supplementation And Human Heat Tolerance: Mechanisms, Evidence, And Integration With Heat Acclimation, Cooling, And Hydration, Siavash Naddafha, Jeffrey R. Stout, Cassandra Evans Feb 2026

Taurine Supplementation And Human Heat Tolerance: Mechanisms, Evidence, And Integration With Heat Acclimation, Cooling, And Hydration, Siavash Naddafha, Jeffrey R. Stout, Cassandra Evans

Research outputs 2022 to 2026

Heat exposure during strenuous exercise increases core temperature and cardiovascular strain, impairing performance and elevating the risk of heat illness. Standard countermeasures include heat acclimation, cooling, and hydration/electrolyte planning. Taurine is a sulfur-containing amino acid present in excitable tissues and widely used as an oral supplement; emerging human trials suggest it can augment thermoregulation, primarily by enhancing eccrine sweating and evaporative heat loss. This narrative review synthesizes mechanistic and applied evidence on taurine during exercise in hot environments and evaluates potential interactions with acclimation, cooling strategies (pre- and per-cooling), and hydration practices. Across a small number of randomized, mostly double-blind …

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The Impact Of A Structured Training Program On The Depth Perception Of Ab Initio Drone Pilots, John Murray, Steven Richardson, Keith Joiner, Graham Wild Feb 2026

The Impact Of A Structured Training Program On The Depth Perception Of Ab Initio Drone Pilots, John Murray, Steven Richardson, Keith Joiner, Graham Wild

Research outputs 2022 to 2026

Highlights: What are the main findings? First empirical assessment of depth-perception improvement from an official RPAS training program. Demonstrates measurable perceptual-skill gains despite no explicit syllabus objective for depth perception. What are the implications of the main findings? Conducted in authentic operational settings under regulated conditions, ensuring strong external validity. Establishes a validated baseline for future comparative and longitudinal studies on perceptual training effectiveness. Flying remotely requires accurate perception of the environment to ensure safe operation. While remotely piloted aircraft (RPA) bring unique opportunities, they also present new challenges for the pilot, including exercising accurate depth perception. The impact of …

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In-Situ Carbon Mineralization Through Injection Of Co2-Saturated Water Into Basalts: Effects On Pore Network, Seyi Philemon Akanji, Lionel Esteban, Ausama Giwelli, Joel Sarout, Alireza Keshavarz, Stefan Iglauer Feb 2026

In-Situ Carbon Mineralization Through Injection Of Co2-Saturated Water Into Basalts: Effects On Pore Network, Seyi Philemon Akanji, Lionel Esteban, Ausama Giwelli, Joel Sarout, Alireza Keshavarz, Stefan Iglauer

Research outputs 2022 to 2026

Carbon capture and storage (CCS) offers the potential to remove and safely store significant quantities of carbon dioxide from the atmosphere, thereby limiting global warming. Conventional geological storage involves injecting CO2, in gaseous or supercritical state, into porous rock reservoirs, relying on geological top seals, capillary forces and/or dissolution in groundwater as the primary “locking-in” processes. An alternative method injects CO2-saturated water into mafic rocks (basalts), chemically inducing in-situ mineralization of CO2 to form solid carbonate minerals. This mechanism offers the lowest risk of carbon returning to the atmosphere. This review synthesizes field and laboratory studies on CO2 mineralization in …

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Novel Buxus Papillosa-Assisted Green Synthesis Of Copper And Nickel Oxide Nanoparticles With Enhanced Catalytic Degradation Of Alizarin Red S Dye, Afrah Zahid, Warda Hassan, Syed Awais Ali, Zahoor Ullah, Mohammad Younas, Syed Nasir Shah, Ali Fatehizadeh, Mashallah Rezakazemi Feb 2026

Novel Buxus Papillosa-Assisted Green Synthesis Of Copper And Nickel Oxide Nanoparticles With Enhanced Catalytic Degradation Of Alizarin Red S Dye, Afrah Zahid, Warda Hassan, Syed Awais Ali, Zahoor Ullah, Mohammad Younas, Syed Nasir Shah, Ali Fatehizadeh, Mashallah Rezakazemi

Research outputs 2022 to 2026

In this work, the biogenic synthesis route using the leaf extract of Buxus papillosa was employed for the green synthesis of copper oxide (CuO) and nickel oxide (NiO) nanoparticles (NPs), which were then applied for the catalytic degradation of Alizarin Red S dye (ARS) as a model organic pollutant. Scanning electron microscopy (SEM) analysis confirmed spherical and rod-like morphologies for CuO and NiO NPs, respectively, while Energy dispersive spectroscopy (EDS) verified their elemental composition. The average crystallite sizes of CuO and NiO NPs were 6.21 and 5.94 nm, respectively, as determined by X-ray diffraction (XRD), and their optical band gaps …

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Reflection On Community-Diversified Influence Maximization In Social Networks, Jianxin Li, Taotao Cai, Ke Deng, Timos Sellis, Feng Xia Feb 2026

Reflection On Community-Diversified Influence Maximization In Social Networks, Jianxin Li, Taotao Cai, Ke Deng, Timos Sellis, Feng Xia

Research outputs 2022 to 2026

To celebrate the 50th Anniversary of the Information Systems Journal, we are delighted to share our research reflections on the article “Community-diversified influence maximization in social networks” published at Information Systems in 2020. Our reflections will highlight the impact of this article on the authors’ research trajectories, its influence on the broader research community, and its contributions to industry practice.

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Comment On ‘Muscle-Specific Strength Better Predicts Physical Performance Decline Than Conventional Metrics: The I-Lan Longitudinal Aging Study’ By Chien Et Al., Ricardo M. Lima, Anthony J. Blazevich Feb 2026

Comment On ‘Muscle-Specific Strength Better Predicts Physical Performance Decline Than Conventional Metrics: The I-Lan Longitudinal Aging Study’ By Chien Et Al., Ricardo M. Lima, Anthony J. Blazevich

Research outputs 2022 to 2026

No abstract provided.

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Getting Edgy: Implications Of Fragmented Seagrass Meadows For Fish Assemblages, Simone Strydom, Kathy Murray, Molly Moustaka, Glenn Hyndes, Shaun Wilson Feb 2026

Getting Edgy: Implications Of Fragmented Seagrass Meadows For Fish Assemblages, Simone Strydom, Kathy Murray, Molly Moustaka, Glenn Hyndes, Shaun Wilson

Research outputs 2022 to 2026

Context: Seagrasses are key marine habitats that are increasingly degraded globally due to anthropogenic disturbances and climate change, compromising the ecosystem services they provide. While seagrass loss is often patchy, the ecological consequences of meadow fragmentation on marine fauna remains unclear. Objectives: This study (1) quantified decadal change in seagrass habitat and fragmentation of the globally important meadows of the Shark Bay World Heritage Area following the 2011 marine heatwave (MHW); and (2) assessed how meadow structure and fragmentation influence fish assemblages. Methods: We integrated in situ seagrass data with seascape metrics derived from habitat maps generated from satellite imagery …

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Efficient Privacy-Preserving Conjunctive Searchable Encryption For Cloud-Iot Healthcare Systems, Jiadi Ma, Tianqi Peng, Gong Bei, Muhammad Waqas, Hisham Alasmary, Sheng Chen Feb 2026

Efficient Privacy-Preserving Conjunctive Searchable Encryption For Cloud-Iot Healthcare Systems, Jiadi Ma, Tianqi Peng, Gong Bei, Muhammad Waqas, Hisham Alasmary, Sheng Chen

Research outputs 2022 to 2026

In cloud-Internet of Things (IoT) healthcare systems, private medical data leakage is a serious concern as the cloud server is not fully trusted. Dynamic searchable symmetric encryption (DSSE), with necessary forward and backward privacy security properties, enables doctors to retrieve ciphertexts while guaranteeing data privacy. However, existing forward and backward private DSSE schemes are not well-suited for cloud-IoT healthcare systems with attribute-value type databases. To this end, we propose an efficient privacy-preserving conjunctive searchable encryption scheme for cloud-IoT healthcare systems, called PC-SE. It is the first conjunctive DSSE scheme designed for attribute-value type databases. Specifically, we design flexible search capabilities …

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Harmonizing Neuropsychological Test Data Across Prospective Studies, Rosita Shishegar, James D. Doecke, Yen Ying Lim, Pierrick Bourgeat, Vincent Dore, Bhargav Tallapragada, Simon M. Laws, Tenielle Porter, Samantha Burnham, Azadeh Feizpour, Ashley Gillman, Michael Weiner, Jason Hassenstab, Christopher C. Rowe, Victor L. Villemagne, Colin L. Masters, Jurgen Fripp, Hamid Sohrabi, Paul Maruff Feb 2026

Harmonizing Neuropsychological Test Data Across Prospective Studies, Rosita Shishegar, James D. Doecke, Yen Ying Lim, Pierrick Bourgeat, Vincent Dore, Bhargav Tallapragada, Simon M. Laws, Tenielle Porter, Samantha Burnham, Azadeh Feizpour, Ashley Gillman, Michael Weiner, Jason Hassenstab, Christopher C. Rowe, Victor L. Villemagne, Colin L. Masters, Jurgen Fripp, Hamid Sohrabi, Paul Maruff

Research outputs 2022 to 2026

Introduction: Alzheimer's disease (AD) research relies on large datasets and advanced statistical models. However, individual population studies often lack sufficient sample size for conclusive results. Harmonizing cognitive test data across studies can address this gap, despite differences in testing protocols. This study harmonizes cognitive data from three major AD cohorts to support robust clinical–pathological modelling. Methods: Information from the Alzheimer's Disease Neuroimaging Initiative (N = 1446); Australian Imaging, Biomarkers and Lifestyle (N = 1764); and Open Access Series of Imaging Studies-3 (N = 440) were integrated, including cognitive scores, demographics, genetics, and clinical and neuroimaging data. Neuropsychological tests relevant to …

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Regulation Of Autophagy-Mediated Pathways By Diet, Physical Activity, And Sleep In Alzheimer's Disease, Ajish Ariyath, Zoe Mputhia, Christopher Dougherty, Bushra Kaleelur Rahuman, W. M.A.D.Binosha Fernando, Belinda Brown, Samantha L. Gardener, Stephanie R. Rainey-Smith, Ralph Martins, Prashant Bharadwaj Feb 2026

Regulation Of Autophagy-Mediated Pathways By Diet, Physical Activity, And Sleep In Alzheimer's Disease, Ajish Ariyath, Zoe Mputhia, Christopher Dougherty, Bushra Kaleelur Rahuman, W. M.A.D.Binosha Fernando, Belinda Brown, Samantha L. Gardener, Stephanie R. Rainey-Smith, Ralph Martins, Prashant Bharadwaj

Research outputs 2022 to 2026

Alzheimer's disease (AD) is a progressive, age-related, neurodegenerative disorder marked by cognitive decline, memory loss, and accumulation of amyloid beta (Aβ) plaques and tau tangles. A key feature of AD is impaired protein homeostasis, often driven by autophagy dysfunction. Autophagy, a cellular degradation and recycling process, plays a vital role in maintaining neuronal health and is increasingly recognized as a therapeutic target in AD. Lifestyle factors such as diet, physical activity, and sleep can positively influence autophagy and support cognitive function. Intermittent fasting (IF) and calorie restriction (CR) activate autophagy and promote longevity; physical activity enhances cerebral blood flow and …

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Beyond The Hype: Organisational Adoption Of Generative Ai Through The Lens Of The Toe Framework–A Mixed Methods Perspective, Laurie Hughes, Fern Davies, Keyao Li, Senali Madugoda Gunaratnege, Tegwen Malik, Yogesh K. Dwivedi Feb 2026

Beyond The Hype: Organisational Adoption Of Generative Ai Through The Lens Of The Toe Framework–A Mixed Methods Perspective, Laurie Hughes, Fern Davies, Keyao Li, Senali Madugoda Gunaratnege, Tegwen Malik, Yogesh K. Dwivedi

Research outputs 2022 to 2026

It is widely accepted that the impact of Generative Artificial Intelligence (GenAI) has been nothing short of transformational, with tangible impacts on industry, education, healthcare and government. But beyond the headlines, how are organisations actually using GenAI, what are the key challenges experienced by decision makers and has the reality on the ground matched the hype? This study adopts a mixed-methods approach, utilising the Technology-Organisation-Environment (TOE) framework to reveal greater insights to how organisations are adopting GenAI, the drivers that affect decision making and the key challenges associated with greater use of the technology. This research adopts a mixed method …

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Children's Experiences Of Functional Constipation: A Qualitative Reflexive Thematic Analysis, Gunilla Flankegård, Patrik Rytterström, Berit M. Gustafsson, Evalotte Mörelius Feb 2026

Children's Experiences Of Functional Constipation: A Qualitative Reflexive Thematic Analysis, Gunilla Flankegård, Patrik Rytterström, Berit M. Gustafsson, Evalotte Mörelius

Research outputs 2022 to 2026

Background: Childhood functional constipation, a common concern within child healthcare, necessitates oral and rectal medical treatments, that are mostly administered by parents in the home environment. It is important to gather children's perspectives in child- and family-centred care. The private nature of toileting, bowel movements, and faecal incontinence are areas of taboo and stigmatisation. Research is scarce on how children perceive this common but private situation of oral and rectal constipation treatment. Objective: To explore children's experiences of functional constipation and its treatments. Design: A qualitative interview study with a constructionist epistemology and a predominantly experiential orientation. Setting: Individual interviews …

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Intrapartum Experiences Of Gestational Surrogates And Intended Parents In Australia: A Qualitative Study, Jutharat Attawet, Leo Ng, Evie Kendal, Yunjing Qiu, Myles Ojabo, Sarah Jefford, Micah D.J. Peters Feb 2026

Intrapartum Experiences Of Gestational Surrogates And Intended Parents In Australia: A Qualitative Study, Jutharat Attawet, Leo Ng, Evie Kendal, Yunjing Qiu, Myles Ojabo, Sarah Jefford, Micah D.J. Peters

Research outputs 2022 to 2026

Background Gestational surrogacy is an increasingly visible, though tightly regulated, pathway to parenthood in Australia, yet intrapartum care remains under-examined. Existing maternity models are grounded in woman-centred care and offer limited guidance for births involving surrogates and intended parents within a triadic care relationship. Objectives To describe the intrapartum experiences of gestational surrogates and intended parents in Australia and to identify care processes that support or hinder respectful, inclusive practice. Methods A descriptive qualitative study was conducted with purposive sampling. Seventeen participants took part between December 2024 and May 2025, comprising nine gestational surrogates and eight intended parents who had …

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Mitigating Malware Prevalence In Networks With Arbitrary Topologies: A Flip-It Cyber Game Approach Integrated With Epidemic Modeling, Mousa Tayseer Jafar, Lu Xing Yang, Gang Li, Robin Doss, Kon Mouzakis, Rajesh Vasa, Helge Janicke, Ahmed Ibrahim, Ahmed Mohsin, Iqbal H. Sarker, Kristen Moore, Seyit Camtepe, Diksha Goel Feb 2026

Mitigating Malware Prevalence In Networks With Arbitrary Topologies: A Flip-It Cyber Game Approach Integrated With Epidemic Modeling, Mousa Tayseer Jafar, Lu Xing Yang, Gang Li, Robin Doss, Kon Mouzakis, Rajesh Vasa, Helge Janicke, Ahmed Ibrahim, Ahmed Mohsin, Iqbal H. Sarker, Kristen Moore, Seyit Camtepe, Diksha Goel

Research outputs 2022 to 2026

Cyber threats have evolved in complexity, aiming at a wide range of sectors using advanced methods and tools. This evolving threat landscape challenges existing cybersecurity frameworks, many of which lack the adaptability to counteract the complex tactics of sophisticated adversaries. Developing robust cyber defense strategies requires simulating dynamic interactions between attackers and defenders across high, moderate, and low-impact scenarios. The Flip-It cyber game serves as an intelligent framework for simulating these interactions, enabling the analysis of adaptive strategies in cybersecurity. This paper aims to address the problem of mitigating malware prevalence with full consideration of attack/defense capabilities in arbitrary network …

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