Digital Commons Network^™

Evaluation Of A Theoretical And Experiential Training Programme For Allied Healthcare Providers To Prescribe Exercise Among Persons With Multiple Sclerosis: A Co-Designed Effectiveness-Implementation Study, Yvonne C. Learmonth, Georgios Mavropalias, Kym Wansbrough

Research outputs 2022 to 2026

Background: Multiple sclerosis (MS) is the most prevalent neurological disorder in young adults, characterised by physical, psychological and cognitive dysfunction. Exercise training is a safe management strategy. Healthcare providers (HCPs) acknowledge deficiencies in awareness, counselling strategies, and resources that prevent them from promoting and prescribing this effective treatment. We implemented an online evidence-based educational programme and evaluated the effect, acceptability, appropriateness, and feasibility of the programme in improving HCP confidence, knowledge, and attitudes towards remote exercise prescription to persons with MS. Methods: Physiotherapists and exercise physiologists were recruited and received the educational programme (online theory and 16-week experience of prescribing …

Lower Limb Muscle Strength Matters: Effect Of Relative Isometric Strength On Countermovement And Rebound Jump Performance In Elite Youth Female Soccer Players, Jack Fahey, Paul Comfort, Nicholas Joel Ripley

Research outputs 2022 to 2026

Background: Expression of maximal and rapid force in the hip, knee, and plantar flexors is important for athletic performance in female soccer. This study was designed to determine the effect of relative isometric strength in the isometric mid-thigh pull (IMTP) on countermovement jump (CMJ) and rebound jump (CMJ-R) performance in female youth soccer players. Methods: Ninety-six female soccer players (age: 14.1 ± 2.3 years, height: 160.5 ± 9.7 cm, mass: 55.0 ± 10.3 kg) completed three trials of the IMTP, CMJ, and CMJ-R using force plates. Players were categorized as stronger (top quartile, n = 19) and weaker players (bottom …

The Luminos Project: Co-Designing A Short-Stay Suicide Support Model For Young People, Aims Hansen, Samantha Speirs, Kirsten Panton, Jacinta Freeman, Zrinka Highfield, Kieren Marshall, Eleanor Tighe, Laura Hemming, Bep Uink, Francis Mitrou, Vu Vuong, Ashleigh Lin

Research outputs 2022 to 2026

Background: Suicide was the leading cause of death among young Australians aged 15–24 years old in 2023, with 392 lives lost. The continued high numbers of youth suicide demand urgent exploration of alternative approaches to suicide intervention in this population. The United Kingdom-based suicide service Maytree offers an innovative short-term stay for people experiencing suicidal thoughts. Grounded by the Maytree model-of-care, the aim of the current study was to co-design a short-stay service responsive to the specific needs of suicidal young people. Methods: Semi-structured and focus group interviews with young people (n = 38), caregivers (n = 11) and key …

Combining Lumipulse P-Tau217 And Aβ42/40 As Confirmatory Tests For Aβ Positivity Prior To Disease-Modifying Therapy, James D. Doecke, Ahmed Chenna, Mintzu Lo, Youssouf Badal, Brandon Yee, Robert Martone, Christos Petropoulos, Christopher J. Fowler, Simon Laws, Stephanie R. Rainey-Smith, Ralph N. Martins, Christopher C. Rowe, Colin L. Masters, John Winslow

Research outputs 2022 to 2026

Introduction: For a blood-based biomarker to be considered a confirmatory test for the detection of abnormal amyloid beta (Aβ) levels, the sensitivity and specificity must be equivalent to that of current cerebrospinal fluid tests. Methods: In the current study we assessed the ability of phosphorylated tau (p-tau)217 and Aβ42/40 from the Lumipulse G p-tau217 and β-amyloid ratio (1-42/1-40) tests, individually and combined, to predict Aβ positron emission tomography status in two sub-cohorts from the Australian Imaging, Biomarkers, and Lifestyle Study of Ageing. Results: Testing an Alzheimer's disease continuum cohort, the area under the curve (AUC), sensitivity, specificity, and accuracy for …

History Informing The Future Of Exercise Oncology, Daniel A. Galvão, Kerry S. Courneya, Alejandro Lucia, Anne M. May, Karen Mustian, Allison B. Warner, Wiskemann Joachim, Karen Wonders, Kathryn H. Schmitz, Robert U. Newton

Research outputs 2022 to 2026

Exercise is increasingly recognized by patients, clinicians, and allied health professionals globally as an important component of cancer care. In this paper, we provide a viewpoint on developments in exercise oncology over the past 4 decades leading up to the creation of the International Society of Exercise Oncology (ISEO). We briefly review research in adult and pediatric cancers from early foundation studies to larger randomized controlled trials published in mainstream oncology journals alongside critical work undertaken in exercise and cancer biological mechanisms. We also discuss potential strengths, weaknesses, opportunities, and threats facing ISEO in becoming a global forum for exercise …

Methodological Insights From Evaluating A Family Member's Voice Reorientation Programme: An Interpretive Descriptive Approach., Johnson U. Gideon, Towell-Barnard Amanda, Mclean Christopher, Robert Glenn, Ewens Beverley

Research outputs 2022 to 2026

Background: Delirium is a prevalent acute brain dysfunction in patients within intensive care units. Delirium is marked by a fluctuating mental state, inattention, and altered consciousness. This condition affects a substantial proportion of patients in intensive care units, and which leads to increased mortality, severe physiological and psychological consequences, and a significant economic burden on healthcare systems. Despite the evidence that supports the use of non-pharmacological interventions to prevent or minimise the impact of delirium such as orientation, sensory stimulation, early mobilisation, and family involvement, their implementation in intensive care units remains inconsistent. The involvement of family members in the …

Review Of Alcohol Use Among Aboriginal And Torres Strait Islander Peoples: Patterns, Impacts And Community-Led Responses, Teagan J. Weatherall, Ks Kylie Lee, Annalee Stearne, Monika Dzidowska, Nicole Hewlett, Lynette Bullen, Taleah Reynolds, Summer Loggins, James H. Conigrave

Journal of the Australian Indigenous HealthInfoNet

This review provides an overview of alcohol use among Aboriginal and Torres Strait Islander peoples using the latest research available. It has been designed to update the evidence published since the previous review conducted in 2018 on this topic (Review of the harmful use of alcohol among Aboriginal and Torres Strait Islander people by Prof Dennis Gray, Dr Annalee Stearne and colleagues) (Gray et al., 2018).

In this updated review, we discuss the historical context and scope of alcohol use among Aboriginal and Torres Strait Islander peoples, impacts on individuals and whole communities, relevant national policies and strategies, present …

Enhancing Person-Centred Care In The Final Years Of Life: Insights From Emergency Department Visits And Hospitalisations In Victorian Residential Aged Care (2015/16 To 2022/23), Janine J. Alan, Bridget Laging, Peter Cameron, Rohan Laging, James Boyd, Davina Porock, Sean Randall

Research outputs 2022 to 2026

Objective: To explore emergency hospitalisations from Victorian residential aged care facilities (RACFs). Methods: Retrospective descriptive study of Victorian RACFs transfers to ED from 2015/16 to 2022/23. Main outcome measures: (1) ED event rate per 100 RACF beds; (2) Number of ED events, day/time, triage category, reason, comorbidity profile, length of stay, death within 12 months of ED presentation and costs; (3) Relationship between resident characteristics and total ED events; (4) Number of inpatient events, comorbidity profile, length of stay, intensive care use, preventable hospitalisations, diagnosis-related group, deaths and costs. Results: The rate of ED presentations from Victorian RACFs from 2015/16 …

Optimising Exercise For Managing Chemotherapy-Induced Peripheral Neuropathy In People Diagnosed With Cancer, Dhiaan Sidhu, Jodie Cochrane Wilkie, Jena Buchan, Kellie Toohey

Research outputs 2022 to 2026

Background: Chemotherapy-induced peripheral neuropathy is a common and debilitating side effect of cancer treatment. While exercise has shown promise in alleviating this burden, it remains underutilised in clinical practice due to the lack of accessible, clinician-friendly guidance. Aim: This review aimed to synthesise current evidence on exercise interventions for managing chemotherapy-induced peripheral neuropathy and provide practical insights to support clinicians in integrating these approaches into patient care. Methods: A search was conducted across MEDLINE, CINAHL, and SPORTDiscus using keywords related to exercise and CIPN. Studies were included if they involved adults receiving neurotoxic chemotherapy and exercise-based interventions. Two authors independently …

Parenting In The Age Of Social Media: The Buffering Effect Of Parental Self-Efficacy On The Relationship Between Parental Social Media Use And Parent Child-Relationship Quality, Celeste Tipple, Cindy Branch-Smith

Research outputs 2022 to 2026

The widespread use of technology in daily life has raised concerns about its potential to disrupt social relationships, particularly within one of the most important human relationships: the parent-child relationship. This study assesses whether parental social media use (measured by a novel parental social media intensity scale) affects the parent-child relationship (measured by the child-parent relationship scale – short form), and whether parental self-efficacy (PSE, measured by the parenting sense of competence scale) moderates this effect. A cross-sectional, online survey study using correlational methods was utilised, with a final sample of 89 parents and caregivers (71.9 % women), averaging 42.6 …

The Moderating Effect Of Dietary Patterns On The Association Of Depression And Anxiety With Cognitive Function, Hilal Salim Said Al Shamsi, Samantha L. Gardener, Hamid R. Sohrabi, Kevin Taddei, Colin L. Masters, Stephanie R. Rainey-Smith, Ralph N. Martins, W. M.A.D.B. Fernando

Research outputs 2022 to 2026

Background and aims: Investigating modifiable risk factors, such as diet, is crucial in understanding their effects on the relationship between Alzheimer's disease (AD)-related cognitive decline and related conditions. This study assesses whether dietary patterns moderate the relationship between symptoms of depression, anxiety, and cognitive function in older adults. Given that biological and psychosocial differences between sexes may influence dietary behaviours, mental health symptoms, and cognitive outcomes, conducting sex-stratified analyses will allow for identification of differential associations. Method: Cross-sectional data from cognitively unimpaired older adults (n = 1174, age ≥60 years) from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study were …

A Single Bout Of Resistance Or High-Intensity Interval Training Increases Anti-Cancer Myokines And Suppresses Cancer Cell Growth In Vitro In Survivors Of Breast Cancer, Francesco Bettariga, Dennis R. Taaffe, Cristina Crespo-Garcia, Timothy D. Clay, Mauro De Santi, Giulia Baldelli, Sanjeev Adhikari, Elin S. Gray, Daniel A. Galvão, Robert U. Newton

Research outputs 2022 to 2026

Purpose: Breast cancer is the leading cause of cancer-related death in women, highlighting the need for strategies to mitigate recurrence and mortality. We examined the effects of a single bout of resistance training (RT) versus high-intensity interval training (HIIT) on anti-cancer myokines and in vitro cancer cell suppression. Methods: Thirty-two survivors of breast cancer were randomly allocated to a single bout of RT (n = 16) or HIIT (n = 16). Blood was collected before, immediately post (0P) and 30 min post (30P) exercise. We measured serum levels of decorin, interleukin 6 (IL-6), secreted protein acidic and rich in cysteine …

Compassionate Self-Care For Nurses And Midwives: A Sequential Explanatory Mixed Methods Study, Mary Steen, Shwikar Othman, Jennifer Fereday, Annette Briley, Qunyan Xu, Rachael Vernon

Research outputs 2022 to 2026

Background: Awareness of being kind and compassionate to yourself is often overlooked despite emerging evidence that high levels of self-compassion decrease levels of anxiety and improves well-being. Aim: To explore what being compassionate to yourself means to nurses and midwives and increase knowledge and understanding of how self-compassion may enhance well-being. Methods: Mixed methods study design was utilised to investigate and explore the influence of self-compassion on nurses and midwives' well-being. Phase 1 involved quantitative data collection and analysis. Phase 2 qualitative data were collected to expand on quantitative results. Results: Fifty-four participants responded to a pre-workshop questionnaire, 55 completed …

Digital Tools To Promote Or Measure Health Literacy In Children Aged 3–5 Years: Scoping Review, Caron Molster, Jennifer Irvine, Amanda Devine, Ruth Wallace, Lennie Barblett, Leesa Costello

Research outputs 2022 to 2026

Health literacy is a determinant of health that should be promoted and measured in early childhood. In the era of digitalization, this could involve digital platforms. However, little knowledge exists on the extent, range, and nature of literature on digital tools for promoting or measuring young children’s health literacy. Addressing this gap, a scoping review was undertaken to explore what digital health literacy tools for children aged 3–5 years could be identified in the literature, what their key features were, how they were designed, whether children were codesigners, and whether the tools had been evaluated. Eligibility criteria included the literature …

Exploring Behavioural Motivations Of Treatment Refusal In Cancer: A Q-Methodological Approach, Ruby Koyllor A. Gleeson, Nicolas H. Hart, Darren Haywood, Frank D. Baughman

Research outputs 2022 to 2026

Background: Cancer treatment refusal is known to lower survival rates and increase cancer symptoms in individuals with cancer. Behavioural motivations of treatment refusal need to be elucidated for better cancer care. Using Q-methodology, a mixed methods research approach, we explored behavioural motivations of treatment refusal in individuals diagnosed with cancer. Method: Thirty-nine individuals (n = 39; age = 49.2 ± 12.2 years) were recruited from Australia, the UK, and the USA, who had refused cancer treatment within the past decade. Participants completed an online demographic questionnaire and a Q-sort activity which required the organisation and ranking of 44 statements on …

Skilled Migrants' Experiences Of Othering, Alterity And Language Policing, Uma Jogulu, Maggie Mcalinden, Melissa A. Parris, Juliana Mutum

Research outputs 2022 to 2026

The Australian Permanent Migration Program and related settlement services have been critical to Australia's success as a stable, democratic and culturally diverse nation. However, emerging research has revealed that this success may come with a high price for as many as one in four skilled migrants who find themselves employed beneath their level of education, expertise and experience, which we define as underemployment. We designed a study that sought to understand the settlement experiences of 36 Asia-Pacific-skilled migrants working as managers. Incorporating Spivak's concepts of subalternity, othering and alterity as a theoretical framework, our analysis uncovered how migrant identity intersected …

The Generality Of Psychosocial Safety Climate Theory—A Fundamental Element For Global Worker Well-Being: Evidence From Four Nations, May Young Loh, Michelle Chin Chin Lee, Maureen Dollard, Dianne Gardner, Kazuki Kikunaga, Tsukumi Tondokoro, Akinori Nakata, Mohd Awang Idris, Tim Bentley, Ali Afsharian, David Tappin, Darryl Forsyth

Research outputs 2022 to 2026

Occupational health and safety researchers and policymakers often rely on organisational theories and evidence to provide valuable information for effective policy making and understanding. Yet, most traditional and contemporary organisational theories are developed within a single nation, often in high-income countries. Therefore, cross-national validation is required for generalisable worldwide use. The current study focuses on an antecedent to workplace health and safety, that is, the psychosocial safety climate (PSC), and aims to investigate if PSC is an etic (i.e., universally applicable) or emic (i.e., nationally/context specific) theory. Across nations, we investigate the construct meaning of PSC by testing PSC measurement …

The Role Of Diet In Moderating The Relationship Between Symptoms Of Depression And Brain Amyloid Load, Hilal Salim Said J. Al Shamsi, Samantha L. Gardener, Stephanie R. Rainey-Smith, Hamid R. Sohrabi, Kevin C.M. Taddei, Colin L. Masters, Vincent M. Doré, Christopher L. Rowe, W. M.A.D.Binosha Fernando, Ralph N. Martins

Research outputs 2022 to 2026

Background: Healthy lifestyle factors, including diet, may affect brain amyloid beta (Aβ) load. This study examines dietary patterns as moderators of the relationships among symptoms of depression, anxiety, and brain Aβ load. Method: A cross-sectional study of cognitively unimpaired older adults (n = 524) from the Australian Imaging, Biomarkers, and Lifestyle study assessed dietary patterns, depressive and anxiety symptoms, and brain Aβ load. Moderation and simple slope analyses were conducted. Results: The Dietary Approaches to Stop Hypertension (DASH) diet moderated the relationship between depressive and anxiety symptoms and brain Aβ load. Higher symptoms were associated with greater Aβ load in …

Behaviour Change Design For Reducing Plastic Usage By Perceived Similarity Nudge, Quentin Ehkirch, Ferdi Raharja, Udari Samaranayake, Ken Ichi Sawai, Akane Matsumae

Research outputs 2022 to 2026

This study explores the influence of perceived similarity on pro-environmental behavior, focusing on plastic reduction. Participants' daily plastic use and reduction were tracked over 30 days via online chat software, with controlled nudges from an agent. Each group included two examinees and one agent. Behavioral data were analyzed to evaluate predictability from various perspectives and its relationship with behavioral change. Results showed significant differences in predictability based on perceived similarity, particularly during the first 10 days. Furthermore, nudges, consumption levels, and behavioral changes significantly affected predictability within the first 20 days. These findings contribute to understanding how perceived similarity can …

Understanding The Role Of Sports Injury Management By Australian Osteopaths: A Cross Sectional Survey Of 992 Practitioners, Brett Vaughan, Jon Adams, Wenbo Peng, Lauren V. Fortington, Michael Fleischmann, Kylie Fitzgerald, Amie Steel, David Sibritt

Research outputs 2022 to 2026

Sport-related injuries are common presentations to primary care and hospital settings. Australian osteopaths practice mainly in private clinical settings in which the frequency of sport-related injury presentations, and how these injuries are managed, is unknown. The objective of the study was to describe the demographic, practice, and clinical management characteristics of Australian osteopaths who report often treating sport-related injuries. The study is a secondary analysis of data derived from the Australian osteopathy practice-based research network. Respondents indicated the frequency treating sports-related injuries in addition to other demographic, practice, and patient management characteristics. Backward logistic regression identified significant characteristics associated with …

Navigating Ethical Challenges In Generative Ai-Enhanced Research: The Ethical Framework For Responsible Generative Ai Use, Douglas Eacersall, Lynette Pretorius, Ivan Smirnov, Erika Spray, Sam Illingworth, Ritesh Chugh, Sonja Strydom, Dianne Stratton-Maher, Jonathan Simmons, Isaac Jennings, Rian Roux, Ruth Kamrowski, Abigail Downie, Chee Ling Thong, Katharine A. Howell

Research outputs 2022 to 2026

The rapid adoption of generative artificial intelligence (GenAI) in research presents both opportunities and ethical challenges that should be carefully navigated. Although GenAI tools can enhance research efficiency by automating tasks such as literature reviews and data analysis, their use raises concerns about aspects including data accuracy, privacy, bias, and research integrity. This paper proposes the ETHICAL framework, which is a practical guide for responsible GenAI use in research. Employing a multi-stage single case study design, we examine multiple GenAI tools in real research contexts to develop the ETHICAL framework, which consists of seven key principles: Examine policies and guidelines, …

Creative Processes In Visual Arts In Education: A Conceptual Framework, Enock Swanzy-Impraim

Research outputs 2022 to 2026

The diversity and uniqueness of individuals and the multifaceted nature of creativity necessitate new models in various domains. This study reviewed previous studies and models of the creative process and presented a combined model (Swanzy-Impraim panoramic creative process model) of the creative process applicable to the visual arts in education and other artist-expressive domains. It positions the creative process in seven phases: (1) immersion, (2) problem/task identification, (3) ideation, (4) production, (5) outcome, (6) evaluation, and (7) responses. This conceptual paper explores creativity as a concept and its significance in the artists’ expressive domain, reviews and maps creative process models, …

The Impact Of Configuration Management Decisions On Firm Resilience: Integrating Resource Configuration, Operational Flexibility, And Collaborative Supply Chain Strategies, Zeplin Jiwa Husada Tarigan, Sahnaz Ubud, Zefanya Valentino Bastanta Tarigan, Ferry Jie

Research outputs 2022 to 2026

Global competition requires the company's appropriate rules and policies. The company is trying to build strong, firm resilience to maintain sustainability. The research aims to analyze the influence of management configuration decisions on company resilience through the integration of resource configuration, operational flexibility, and collaboration in the supply chain. This study was conducted on 462 manufacturing companies in Indonesia that were experiencing changes in operational systems and global competitive pressures. Data was collected through questionnaires and analyzed using the Partial Least Square (PLS) method. The research results show that management configuration decisions influence resource configuration and supply chain collaboration integration …

A Cross-Sectional Examination Of Missed Infection Control Practices Among Nurses In The Jordanian Hospitals, Muhammad Ahmed Alshyyab, Rania Ali Albsoul, Gerard Fitzgerald, Diana Arabiat

Research outputs 2022 to 2026

Background: Missed infection control practices may negatively impact quality healthcare and patient safety in acute health care settings. Hence, more research is urgently needed especially in Arab countries. To investigate the elements and reasons of missed infection control activities among nurses in Jordan. The sociodemographic correlates with missed infection control activities were also examined. Methods: A cross sectional design was utilized in this study. A convenience sample of 960 nurses from seven hospitals in the North of Jordan was used. The Missed Nursing Care Infection Prevention and Control (MNCIPC) Survey was employed to collect the data. Data were analyzed using …

Aiding Depth Perception In Initial Drone Training: Evidence From Camera-Assisted Distance Estimation, John Murray, Steven Richardson, Keith Joiner, Graham Wild

Research outputs 2022 to 2026

Remotely Piloted Aircraft (RPA) pilots frequently experience difficulties with depth perception, particularly when estimating distances between the drone and environmental obstacles. This study evaluates whether the use of onboard camera imagery can improve exocentric distance estimation accuracy among ab initio drone pilots operating under visual line-of-sight (VLOS) conditions. Two groups of undergraduate students performed distance estimation tasks at 20 and 50 m. One group used direct observation only to estimate the exocentric distance between the drone and an obstacle. The second group, as well as direct observation, had access to a live video feed from the drone’s onboard camera via …

Exercise Effects On Symptoms Of Depression And Anxiety Vary By Patient, Clinical, And Intervention Characteristics In Cancer Survivors: Results From Pooled Analyses Of Individual Participant Data Of 26 Rcts, Marlou Floor Kenkhuis, Meike Doorenbos, Isa H. Mast, Neil K. Aaronson, Marc Van Beurden, Martin Bohus, Kerry S. Courneya, Amanda J. Daley, Daniel A. Galvão, Martine M. Goedendorp, Wim H. Van Harten, Sandi C. Hayes, Anouk E. Hiensch, Melinda L. Irwin, Marie José Kersten, Hans Knoop, Anne M. May, Alex Mcconnachie, Willem Van Mechelen, Nanette Mutrie, Robert U. Newton, Frans Nollet, Hester S. Oldenburg, Martina E. Schmidt, Kathryn H. Schmitz, Karl Heinz Schulz, Dennis R. Taaffe

Research outputs 2022 to 2026

Purpose: This study aimed to investigate whether socio-demographic, clinical, and intervention-related variables moderate the effects of exercise on depression and anxiety symptoms in cancer survivors. Methods: Data from 26 RCTs in the POLARIS database were analyzed using a one-step individual participant data (IPD) meta-analytic approach with linear mixed models to assess exercise effects on depression and anxiety symptoms (z-scores). Interaction terms were added to these models to explore moderators. Results are presented as betas (corresponding to Cohen’s d effect size). Results: Albeit statistically significant, exercise demonstrated negligible effects on symptoms of depression (β = − 0.11; 95% CI = − …

Time Alters Distinct Memories Driven By Sensory Prediction Errors And Task Errors In Sensorimotor Adaptation, Li Ann Leow, Welber Marinovic, Scott Albert, Timothy J. Carroll

Research outputs 2022 to 2026

Prior learning can impair future learning when the requirements of the two memories conflict, a phenomenon termed anterograde interference. In sensorimotor adaptation, the passage of time between initial and future learning can reduce such interference effects, leading to the interpretation that time consolidates motor memories, protecting motor memories from interference. However, we still do not fully understand how time affects learning, as some studies found no effects of time on interference. One possible explanation for such inconclusive findings is that time has distinct effects on the multiple processes underpinning sensorimotor adaptation, and these processes may compensate for each other's effects …

Amyloid Accumulation, Brain Atrophy, And Cognitive Decline In Emergent Alzheimer's Disease, Ying Xia, Pierrick Bourgeat, Vincent Doré, Jurgen Fripp, Yen Ying Lim, Simon M. Laws, Christopher Fowler, Christopher C. Rowe, Colin L. Masters, Elizabeth J. Coulson, Paul Maruff

Research outputs 2022 to 2026

Introduction : Emergent Alzheimer's disease (AD) represents a transitional stage where cognitively unimpaired (CU) individuals exhibit subthreshold but increasing amyloid-β (Aβ) levels. The impact of Aβ accumulation on brain volume loss and cognition during this early stage remains unclear. Methods: This retrospective cohort study analyzed data from 408 CU participants who were initially Aβ− (< 15 Centiloids) and followed for up to 15 years. Changes in basal forebrain and hippocampal volume, along with domain-specific cognitive performance, were compared between those who progressed to Aβ+ (≥20 Centiloids) and those who remained Aβ−. Results: Sixty-five CU participants progressed to Aβ+, indicating emergent AD, and showed faster Aβ accumulation and subtle memory decline. However, no significant differences in rate of BF and hippocampal atrophy were observed between groups. Discussion: The results suggest that during this emergent phase of AD, Aβ accumulation is associated with episodic memory loss, in the absence of detectable accelerated brain atrophy. Highlights: Identified cognitively unimpaired individuals in the emergent stage of Alzheimer's disease (AD). Emergent AD exhibits a greater rate of amyloid-β (Aβ) accumulation. No accelerated volume loss detected in the basal forebrain or hippocampus. Emergent AD is also associated with a subtle decline in memory. Early Aβ accumulation may impair cognitive function before structural atrophy.

Increasing The Effectiveness Of Rural, Regional And Remote Food Security Initiatives Through Place-Based Partnerships—A Qualitative Study, Stephanie L. Godrich, Melissa Stoneham, Isabelle Chiera, Jess Doe, Amanda Devine, Emily Humphreys

Research outputs 2022 to 2026

Issue Addressed: This work aimed to understand the ways in which local organisations were working in partnership to support food security action in rural, regional, and remote areas. Methods: Semi-structured interviews were conducted with 101 food security initiative leaders, representing 148 food initiatives within Australia's largest state, Western Australia (WA). A thematic analysis was undertaken using NVivo that indicated a total of 378 partnering organisations worked on the food security initiatives. Results: Organisations partnered to address food security in their regions through coordinated action; community consultation; food/financial donations; funding and grants; on-ground programme and service delivery and physical and human …

Navigating Child Oral Health In Western Australia: A Caregiver's Perspective, Lesley Andrew, Elizabeth Wenden, Mohamed Estai, Ruth Wallace

Research outputs 2022 to 2026

Background: Early childhood caries (ECC) is the most common chronic health condition among Australian preschool-aged children. Untreated, ECC can affect children's physical and emotional health and future social opportunities. ECC is largely preventable through primary caregivers' correct understanding of oral health promoting diets, oral hygiene practices and dental service engagement. The study aim is to explore Western Australian (WA) primary caregivers' child oral health knowledge, experience and practices. The Fisher-Owens socioecological model of child oral health was applied across the study to structure and interpret the findings across the complex, interactive sociocultural influences on child oral health. Methods: The mixed-methods …