Digital Commons Network^™

Associations Between Flavonoid Intake And Subclinical Atherosclerosis: The Mesa, Nicola P. Bondonno, Benjamin H. Parmenter, Kevin Murray, Catherine P. Bondonno, Lauren C. Blekkenhorst, Alexis C. Wood, Wendy S. Post, Matthew Allison, Michael H. Criqui, Joshua R. Lewis, Jonathan M. Hodgson

Research outputs 2022 to 2026

Background: Flavonoids may play a role in mitigating atherosclerotic cardiovascular diseases, with evidence suggesting effects may differ between vascular beds. Studies examining associations with subclinical markers of atherosclerosis between subpopulations with different underlying risks of atherosclerosis are lacking. METHODS: Among 5599 participants from the MESA (Multi-Ethnic Study of Atherosclerosis), associations between dietary flavonoid intakes (estimated from a food frequency questionnaire) and subclinical measures of atherosclerosis (ankle-brachial index, carotid plaques and intima-media thickness, and coronary artery calcification) were examined using repeated measures models. Exposures and outcomes were measured at exam 1 (2000-2002) and exam 5 (2010-2011). Stratified analyses and interaction terms …

Physical And Psychological Factors Related To Injury, Illness And Tactical Performance In Law Enforcement Recruits: A Systematic Review, Myles Murphy, Nicole Merrick, Gill Cowen, Vanessa Sutton, Garth Allen, Nicolas H. Hart, Andrea B. Mosler

Research outputs 2022 to 2026

Objective: There are inconsistent reports of factors relating to injury, illness and tactical performance in law enforcement recruits. Our objectives were to: (1) report physical and psychological risk factors and protective factors for injury and illness and (2) report physical and psychological risk factors and protective factors for tactical performance success. Design: Systematic epidemiological review.

Methods: Searches of six databases were conducted on 13 December 2022. We included cohorts that assessed physical and psychological factors for injury, illness and tactical performance success. Study quality was assessed using the Joanna Briggs Institute Quality Assessment Checklist for Prevalence Studies and certainty assessed …

A Flavonoid-Rich Diet Is Associated With Lower Risk And Improved Imaging Biomarkers Of Nonalcoholic Fatty Liver Disease: A Prospective Cohort Study, William Bell, Amy Jennings, Alysha S. Thompson, Nicola P. Bondonno, Anna Tresserra-Rimbau, Tilman Kühn, Aedín Cassidy

Research outputs 2022 to 2026

Background: Mechanistic studies and short-term randomized trials suggest higher intakes of dietary flavonoids may protect against nonalcoholic fatty liver disease (NAFLD).

Objectives: We aimed to perform the first population-based study with long-term follow-up on flavonoid consumption, incident NAFLD, and validated NAFLD biomarkers.

Methods: In a prospective study, we assessed the associations between flavonoid intake based on ≥2 24-h dietary assessments and NAFLD risk among 121,064 adults aged 40–69 y by multivariable Cox regression analyses. We further assessed the associations between flavonoid intake and magnetic resonance imaging-derived liver fat (a subset of n = 11,435) and liver-corrected T1 values (cT1; a …

Adapting A Telehealth Physical Activity And Diet Intervention To A Co-Designed Website For Self-Management After Stroke: Tutorial, Dina Pogrebnoy, Lee Ashton, Brian A. Beh, Meredith Burke, Richard Cullen, Jude Czerenkowski, Julie Davey, Amy M. Dennett, Kevin English, Erin Godecke, Nicole Harper, Elizabeth Lynch, Lesley Macdonald-Wicks, Amanda Patterson, Emily Ramage, Ben Schelfhaut, Dawn B. Simpson, Karly Zacharia, Coralie English

Research outputs 2022 to 2026

People who experience a stroke are at a higher risk of recurrent stroke when compared with people who have not had a stroke. Addressing modifiable risk factors like physical inactivity and poor diet has been shown to improve blood pressure, a leading contributor to stroke. However, survivors of stroke often experience challenges with accessing risk reduction services including long wait lists, difficulty with transportation, fatigue, impaired function, and diminished exercise capacity. Providing health interventions via a website can extend the reach when compared with programs that are only offered face to face or via real-time telehealth. Given global challenges of …

Source-Specific Nitrate Intake And All-Cause Mortality In The Danish Diet, Cancer, And Health Study, Nicola P. Bondonno, Pratik Pokharel, Catherine P. Bondonno, Dorit W. Erichsen, Liezhou Zhong, Jörg Schullehner, Kirsten Frederiksen, Cecilie Kyrø, Peter Fjeldstad Hendriksen, Jonathan M. Hodgson, Frederik Dalgaard, Lauren C. Blekkenhorst, Ole Raaschou-Nielsen, Torben Sigsgaard, Christina C. Dahm, Anne Tjønneland, Anja Olsen

Research outputs 2022 to 2026

Introduction: Nitrate and nitrite are naturally occurring in both plant- and animal-sourced foods, are used as additives in the processing of meat, and are found in water. There is growing evidence that they exhibit a spectrum of health effects, depending on the dietary source. The aim of the study was to examine source-dependent associations between dietary intakes of nitrate/nitrite and both all-cause and cause-specific mortality. Methods: In 52,247 participants of the Danish Diet, Cancer and Health Study, associations between source-dependent nitrate and nitrite intakes––calculated using comprehensive food composition and national drinking water quality monitoring databases––and all-cause, cardiovascular disease (CVD)-related, and …

Escarpments Within Mediterranean Seagrass Posidonia Oceanica Meadows Increase Habitat Heterogeneity And Structural Complexity Enhancing Fish Diversity And Biomass, Enric Gomis, Enric Ballesteros, Irene Bernabeu, Karina Inostroza, Miguel A. Mateo, Oscar Serrano

Research outputs 2022 to 2026

Seagrass meadows provide important ecosystem services including carbon sequestration, coastal protection from erosion, and sustained biodiversity and fisheries thereby improving the wellbeing and livelihoods of coastal communities. The erosion of millenary deposits of intertwined roots and rhizomes of Posidonia results in the formation of three-dimensional structures named escarpments that constitute a biogenic reef habitat. However, the natural history of seagrass escarpments including their formation processes and their role as habitat for reef fauna and flora remains poorly understood. This research located and characterized Posidonia oceanica escarpments in Menorca (Balearic Islands) and compared structural complexity and fish assemblages among seagrass escarpments, …

Higher Plant-Derived Nitrate Intake Is Associated With Lower Odds Of Frailty In A Cross-Sectional Study Of Community-Dwelling Older Women, Eleanor Hayes, Elsa Dent, Oliver M. Shannon, Lie Zhou Zhong, Trent Bozanich, Lauren C. Blekkenhorst, Kun Zhu, Catherine P. Bondonno, Mario Siervo, Emiel O. Hoogendijk, Jonathan M. Hodgson, Richard L. Prince, Joshua R. Lewis, Marc Sim

Research outputs 2022 to 2026

Purpose: Dietary nitrate intake is inversely related to numerous contributors towards frailty, including cardiovascular disease and poor physical function. Whether these findings extend to frailty remain unknown. We investigated if habitual nitrate intake, derived from plants or animal-based foods, was cross-sectionally associated with frailty in women. Methods: Community-dwelling older Australian women (n = 1390, mean age 75.1 ± 2.7 years) completed a validated semi-quantitative food frequency questionnaire (FFQ). Nitrate concentrations in food were obtained from international nitrate databases. We adopted the Rockwood frailty index (FI) of cumulative deficits comprising 33 variables across multiple health domains (scored 0 to 1), which …

Maternal Health Considerations: Highlighting And Advancing Opportunities For Improved Maternal Health, Caitlin Fox-Harding

Research outputs 2022 to 2026

The special collection on Maternal Health Considerations offers a comprehensive exploration of critical issues surrounding maternal well-being across diverse contexts and disciplines. Recognising that maternal health extends beyond the physiological realm, this collection delves into the multifaceted dimensions of maternal well-being, including physical, mental, and socio-ecological factors. The collection comprises a series of interdisciplinary studies that investigate various facets of maternal health, from conception to postpartum stages. It addresses the complex interplay between biological, psychological, and socio-cultural determinants that influence maternal health outcomes. By adopting a holistic approach, the contributors shed light on the interconnectedness of maternal well-being. Key themes …

Variations In Strength-Speed-Power Performance Across The Season: Do True Changes Occur In Elite Rugby Players?, Irineu Loturco, Chris Bishop, Santiago Zabaloy, Túlio B. M. A. Moura, Maurício S. Ramos, Lucas A. Pereira, Michael R. Mcguigan

Research outputs 2022 to 2026

This study aimed to determine, through the use of a highly sensitive statistical tool, whether real changes in performance were present; and compare the rates of meaningful variations in strength, speed, and power parameters at different time-points during the competitive season in national team rugby players. Thirty-two players were assessed 5 times across the season using the following tests: squat jump and countermovement jump tests; 30-m sprint velocity; and one-repetition maximum (1RM) in the half-squat and bench-press exercises. A repeated-measures analysis of variance was conducted to test for differences between successive time-points. Individual coefficients of variation values were used to …

Frailty Knowledge, Training And Barriers To Frailty Management: A National Cross-Sectional Survey Of Health Professionals In Australia, Leila S. Hanjani, Sarah Fox, Ruth E. Hubbard, Emily Gordon, Natasha Reid, Sarah N. Hilmer, Rosemary Saunders, Danijela Gnjidic, Adrienne Young

Research outputs 2022 to 2026

Objective(s): To understand Australian health professionals' perceptions of their knowledge and previous training about frailty, as well as barriers to frailty assessment and management in their practice. Methods: A cross-sectional online survey was developed and distributed to health professionals (medical, nursing and allied health) engaged in clinical practice in Australia through convenience and snowball sampling techniques from March to May 2022. The survey consisted of five sections: frailty training and knowledge; confidence in recognising and managing adults with frailty; the importance and relevance of frailty; barriers to assessing and managing frailty in practice; and interest in further frailty training. Responses …

A Scoping Review Of The Impact Of Food Policy Groups On Local Food Systems In High-Income Countries, Stephanie Louise Godrich, Jess Doe, Sarah Goodwin, Laura Alston, Katherine Kent

Research outputs 2022 to 2026

This scoping review aimed to explore international evidence on the impact of Food Policy Groups (FPGs) on local food systems, in urban and rural regions of high-income countries. Peer-reviewed and grey literature were searched to identify 31 documents published between 2002 and 2022 providing evidence on the impact of FPGs. Activities spanned domains including increasing food equity (e.g. strengthening school meals programs); increasing knowledge and/or demand for healthy food (e.g. food literacy programs with children and adults); increasing food access (e.g. enhancing local food procurement); environmental sustainability (e.g. promoting low-waste food items on café menus); economic development (e.g. ensuring local …

Health Behaviour Profiles In Young Australian Adults In Relation To Physical And Mental Health: The Raine Study, Cecilie Thøgersen-Ntoumani, Daniel F. Gucciardi, Joanne A. Mcveigh, Therese A. O'Sullivan, Manon Dontje, Emmanuel Stamatakis, Peter R. Eastwood, Leon Straker

Research outputs 2022 to 2026

Issues Addressed: We aimed to identify latent health behaviour profiles of young adults and examine their associations with physical and mental health outcomes. We also characterised the profiles by socio-demographic characteristics. Methods: Data were collected between 2012 and 2014. Participants (N = 476) were young adults (M age [SD] = 22.1 [.57] years) from Generation 2 of the Raine Study longitudinal cohort. Health behaviours were measured via ActiGraph GT3X waist monitors (physical activity, sedentary behaviour) and questionnaires (diet quality, alcohol, smoking and sleep). Physical and mental health were measured using clinical health assessments, blood biomarkers, and questionnaires. Latent Profile Analysis …

Study Protocol For A Stepped-Wedge Cluster (Nested) Randomized Controlled Trial Of Antenatal Colostrum Expression (Ace) Instruction In First-Time Mothers: The Ace Study, Cassandra Cuffe, Roslyn Giglia, Matthew N. Cooper, Julie Hill, Desiree Silva, Anita M. Moorhead, Valerie Verhasselt, Joshua R. Lewis, Deborah Ireson, Jill R. Demirci, Talea Cotte, Kathryn Webb, Frances Patey, Therese A. O’Sullivan

Research outputs 2022 to 2026

Background: Although many mothers initiate breastfeeding, supplementation with human-milk substitutes (formula) during the birth hospitalization is common and has been associated with early breastfeeding cessation. Colostrum hand expressed in the last few weeks before birth, known as antenatal colostrum expression (ACE), can be used instead of human-milk substitutes. However, evidence is lacking on the efficacy of ACE on breastfeeding outcomes and in non-diabetic mothers. Methods and Planned Analysis: This multicenter stepped-wedge cluster (nested) randomized controlled trial aims to recruit 945 nulliparous pregnant individuals. The trial is conducted in two phases. During Phase 1, control group participants are under standard care. …

The Gut Microbiome Modulates Associations Between Adherence To A Mediterranean-Style Diet, Abdominal Adiposity, And C-Reactive Protein In Population-Level Analysis, Amy Jennings, Tilman Kühn, Nicola P. Bondonno, Sabina Waniek, Corinna Bang, Andre Franke, Jan Kassubek, Hans-Peter Müller, Marcus Both, Katharina S. Weber, Wolfgang Lieb, Aedín Cassidy

Research outputs 2022 to 2026

Background: Adherence to a Mediterranean-style dietary pattern is likely to have variable effects on body composition, but the impact of gut microbiome on this relationship is unknown. Objectives: To examine the potential mediating effect of the gut microbiome on the associations between Alternate Mediterranean Diet (aMed) scores, abdominal adiposity, and inflammation in population-level analysis. Design: In a community-based sample aged 25 to 83 y (n = 620; 41% female) from Northern Germany, we assessed the role of the gut microbiome, sequenced from 16S rRNA genes, on the associations between aMed scores, estimated using validated food-frequency questionnaires, magnetic resonance imaging-determined visceral …

Unveiling The Link Between Systemic Inflammation Markers And Cognitive Performance Among Older Adults In The Us: A Population-Based Study Using Nhanes 2011–2014 Data, Zheng Guo, Yulu Zheng, Jian Geng, Zhiyuan Wu, Tao Wei, Guangle Shan, Yahong Zhu, Yuanyuan Zheng, Xingang Li

Research outputs 2022 to 2026

Purpose: This study aimed to evaluate the association between systemic inflammation markers and cognitive performance among older US adults. Methods: This cross-sectional study assessed 3,632 older participants from the 2011–2014 National Health and Nutrition Examination Survey (NHANES). The main analysis included participants aged over 60 years. Systemic inflammation markers were quantified by calculating the composite inflammation indicators from the blood routine count, and cognitive performance was assessed using Consortium to Establish a Registry for Alzheimer's Disease (CERAD) test, Animal Fluency test (AFT), and Digit Symbol Substitution test (DSST). Results: There were 2,743 individuals enrolled in the current analysis. The overall …

Exercise Professional Education, Qualifications, And Certifications: A Content Analysis Of Job Postings In The United States, Rachele Pojednic, Devin P. O’Neill, Molly G. Flanagan, Alexis Bartlett, Byron L. G. Carter, Mary A. Kennedy

Research outputs 2022 to 2026

Introduction: Growth in the field of clinical exercise science and the potential impacts on overall health and wellbeing have driven the need for qualified, clinically trained, exercise professionals. And yet, it is not well understood what specific credentials employers are seeking when hiring exercise professionals. Purpose: The purpose of the study was to examine the qualification requirements for professionals seeking employment in exercise science, exercise physiology, kinesiology or equivalent fields. Methods: Search platforms Indeed.com and USAJobs.gov were examined within a two week period in 2022. Search terms included “Exercise Physiology”, “Exercise Science”, “Exercise Professional”, “Exercise Prescription”, “Exercise Specialist”, and “Kinesiology”. …

Overview Of Aboriginal And Torres Strait Islander Health Status 2023, Australian Indigenous Healthinfonet

Research outputs 2022 to 2026

The main purpose of the Overview of Aboriginal and Torres Strait Islander health status (Overview) is to provide a comprehensive summary of the most recent indicators of the health and current health status of Australia’s Aboriginal and Torres Strait Islander people. The Overview has been prepared by HealthInfoNet staff as part of our contribution to supporting those who work in the Aboriginal and Torres Strait Islander health sector. The Overview is a key indicator of the HealthInfoNet’s commitment to authentic and engaged knowledge development and exchange.

The initial sections of this Overview provide information about the context of Aboriginal and …

Summary Of Aboriginal And Torres Strait Islander Health Status - Selected Topics 2023, Australian Indigenous Healthinfonet

Research outputs 2022 to 2026

Aboriginal and Torres Strait Islander people have lived on their traditional lands across Australia, including the Torres Strait Islands, for upwards of 50,000 years and their continuity, history and cultural traditions are unrivalled in the world [1,2] . Before colonisation, Aboriginal and Torres Strait Islander people lived in family and community groups, and moved across the land following seasonal changes [1] . Aboriginal and Torres Strait Islander people developed complex societies, trading systems and agricultural activities that were celebrated and recorded in dance, song and stories [2] . The Aboriginal and Torres Strait Islander concept of health is not just …

Expression Of Growth Differentiation Factor 15 (Gdf-15) In Placental Tissue Of Full- Term Pregnant Women With Hypertensive Disorders In A Western Australian Population, Elsa H. L. Chew

Theses: Doctorates and Masters

Women who experience hypertensive pregnancy disorders (HPDs) during pregnancy, mainly pre-eclampsia (PE), are four times more likely to develop hypertension after pregnancy and therefore have an increased risk of developing cardiovascular diseases (CVD) in the future. Pregnancy involves a high level of cardiovascular stress and the development of some complications. This has the potential to increase a woman’s susceptibility to vascular or metabolic disease risk in the future. In this research, pre-eclampsia (PE) and pregnancyinduced hypertension (PIH) were representatives of HPDs and were analysed together for the expression of Growth Differentiation Factor-15 (GDF-15) relative to their healthy agematched controls.

GDF-15 …

The Food And Habitat Effects Of Detrital Kelp As A Trophic Subsidy To Seagrass-Inhabiting Mesograzers, Jessica Billinghurst

Theses: Doctorates and Masters

Seascapes are connected through the transfer of energy from the movement of fauna, detritus, and nutrients among habitats. This exchange of resources can influence food web dynamics in the recipient system, increasing productivity and biodiversity, thus creating spatial subsidies. Spatial subsidies are usually characterised by the transfer of resources from highly productive donor systems to lower productive recipient systems. However, recent work suggests that recipient systems with comparably high productivity, such as seagrass meadows, may benefit from spatial subsidies. Kelp is regularly eroded from reefs and provides a vector for nutrient and detrital transfer to seagrass meadows, where it can …

Exploring Treatment Burden In People With Type 2 Diabetes Mellitus (T2dm) In Primary Care Settings, Kai Lin

Theses: Doctorates and Masters

Introduction

Treatment burden is the perceived workload of care by individuals. The treatment burden experienced by individuals with Type 2 Diabetes Mellitus (T2DM) is a major obstacle to achieving effective healthcare outcomes. The aim of this research is to facilitate better management of treatment burden in people with T2DM in primary care settings.

Methods

A systematic review, encompassing narrative analysis was used to characterise the treatment burden of T2DM and critical appraisal was used to identify the appropriate patient-reported outcome measures (PROMs) for measuring this burden. The selected instruments were employed with subsequent questionnaires, followed by patient focus groups. A …

Western Australian Mothers' Experiences Of Breastfeeding Support In Hospital After Birth: A Mixed Methods Study, Justine Van Der Watt

Theses: Doctorates and Masters

Background: The benefits of breastfeeding are well established for infants, mothers and the community, with the World Health Organisation recommending that infants be exclusively breastfed up to six months of age with an achievable goal of 70% globally. Yet in Australia only 15-37% may be reaching that goal. There have also been reported benefits and desires for mothers to be supported with their breastfeeding in order to increase and prolong breastfeeding duration and exclusivity, especially early after birth. However, there is limited research or literature exploring what experiences mothers are having with breastfeeding support, especially during their hospital admissions in …

Best Practice Recommendations For Coaching Gymnasts To Avoid Burnout And Reframe Performance Anxiety, Clare A. Mccall

Theses: Doctorates and Masters

Gymnastics is deemed a psychologically demanding sport, with associated risk factors of burnout and performance anxiety. To date, relatively little research has explored the specific goal and perfectionistic processes of gymnasts, despite these risks. This body of work identified the specific goal-related constructs and perfectionistic orientation of young athletes and examined how these associated with burnout and performance anxiety. It comprised of two studies with a mixed methods design. The first study aimed to systematically review literature investigating how goal-related constructs and perfectionism associate with burnout and performance anxiety in young athletes. This review focused on summer and winter Olympic …

The Physiological And Performance Consequences Of The Australian Special Forces Selection Course, Angela Uphill

Theses: Doctorates and Masters

Special Forces (SF) soldiers are the most elite element of military forces, who have undergone rigorous training in order to prepare them for a wide array of specialised missions. In Australia, entry into the SF is determined through the highly competitive SF Selection Course (SF-SC), which is a gruelling program involving extreme physical demands, psychological stress, and restricted access to sleep and nutrition. The stressors involved in arduous military training events such as the SF-SC can result in significant losses of fat mass and lean mass, disruption to hormonal homeostasis, and significant decreases in neuromuscular capacity, which can potentially increase …

The Legal Framework For The Protection Of Victims Of The Worst Forms Of Child Labour In Agriculture In Ghana: A Human Rights Based Approach, Ruby Akua Aglagoh

Theses: Doctorates and Masters

Child labour is prevalent in Ghana, especially in the agriculture industry where children engage in work that is harmful to their health, morals, and safety. Such harmful work has been defined by the ILO Convention No. 182 on the Worst Forms of Child Labour, 1999 as constituting the worst forms of child labour. These children have human rights stated in the laws of Ghana but have become victims of human rights violations because they cannot access the protections provided for under the international conventions and national laws of Ghana.

Using doctrinal legal research, this thesis reviews the legal framework of …

Effects Of Aerobic And Resistance Exercise For 9 Months On Serum Free Light Chains In Type 2 Diabetes, Youyoung Kim, John P. Campbell, Neil M. Johannsen, Timothy S. Church, Eunhan Cho, Jennifer Heaney, Guillaume Spielmann

Research outputs 2022 to 2026

Background and aims: Serum polyclonal free light chains (FLCs) levels are associated with overall survival in the general population, reflecting their utility as a biomarker of underlying immune activation and inflammation. Regular exercise is known to ameliorate low-grade inflammation in chronic diseases such as type 2 diabetes; however, the effects of different exercise training modalities on FLCs in adults with type 2 diabetes is unknown. This study investigated the effects of 9-month of aerobic, resistance or combined supervised exercise on serum FLCs in 164 patients with type 2 diabetes (age 58 ± 8 years; 63% female). Methods: 164 participants from …

A Lack Of Tourism-Based Health Services Amid Global Aging: How Tourism And Health Practices Can Combine To Benefit The Aging Population, Jun Wen

Research outputs 2022 to 2026

No abstract provided.

Envisaging A Thriving Future: The Integration Of Positive Psychology Into Brief Psychotherapy And Family Therapy Practice, Richard Lakeman

Research outputs 2022 to 2026

This paper delves into the pragmatic integration of positive psychology, particularly Seligman's PERMA model, and brief psychotherapy to foster a vision of a thriving future for clients. Despite the entrenched tribalism within psychotherapy that often resists the incorporation of new techniques, a deliberate and flexible approach to integration, rooted in congruence with theoretical frameworks, can overcome these barriers. Positive psychology dovetails neatly with the goals of family therapy by highlighting strengths and resilience. The PERMA model—encompassing Positive emotions, Engagement, Relationships, Meaning and Accomplishment—captures the essence of a flourishing life. While primarily applied in non-clinical settings, its potential to enhance wellbeing …

Prevalence Of Disordered Eating And Its Relationship With Rapid Weight Loss Amongst Male And Female Combat Sport Competitors: A Prospective Study, Colin S. Doherty, Lauren V. Fortington, Oliver R. Barley

Research outputs 2022 to 2026

Objectives:

To compare prevalence and change scores of disordered eating (DE) in combat sport athletes by sex and explore the potential relationship between rapid weight loss (RWL) and DE scores.

Design:

Prospective study based on 24 events (September 2022–2023).

Methods:

A body mass (BM) questionnaire was completed at ~ 1 day post-competition providing pre-competition BM data for − 7 days, − 24 h, and weigh-in. The Athletic Disordered Eating (ADE) online questionnaire was completed at ~ 7 and ~ 28 days post-competition, providing overall DE and four subscale scores (food and energy control, bingeing, body control, and body discontent).

Results: …

Co-Designing An Online Treatment Decision Aid For Men With Low-Risk Prostate Cancer: Navigate, Penelope Schofield, Amelia Hyatt, Alan White, Fiona White, Mark Frydenberg, Suzanne Chambers, Robert Gardiner, Declan G. Murphy, Lawrence Cavedon, Jeremy Millar, Natalie Richards, Barbara Murphy, Ilona Juraskova

Research outputs 2022 to 2026

Objectives: To develop an online treatment decision aid (OTDA) to assist patients with low-risk prostate cancer (LRPC) and their partners in making treatment decisions. Patients and methods: Navigate, an OTDA for LRPC, was rigorously co-designed by patients with a confirmed diagnosis or at risk of LRPC and their partners, clinicians, researchers and website designers/developers. A theoretical model guided the development process. A mixed methods approach was used incorporating (1) evidence for essential design elements for OTDAs; (2) evidence for treatment options for LRPC; (3) an iterative co-design process involving stakeholder workshops and prototype review; and (4) expert rating using the …