Digital Commons Network^™

Preharvest Application Of Abscisic Acid Promotes Fruit Ripening, Colour Development And Modulates Phenylpropanoid Pathway In Early Maturing ‘Yoho’ Persimmon, Mahmood Ul Hasan, Zora Singh, Hafiz Muhammad Shoaib Shah, Eben Afrifa-Yamoah, Andrew Woodward

Research outputs 2022 to 2026

Persimmon is cultivated globally for its distinctive flavour profile and nutritional benefits. Skin colour is one of the important harvest maturity indicators of persimmon fruit, and inadequate colour development in early-maturing cultivars presents significant economic challenges for growers. This study investigated the efficacy of preharvest s-(+)-cis, trans-abscisic acid (S-ABA) spray application on accelerating colour development and improving fruit quality parameters in ‘Yoho’ persimmon. Trees were treated with foliar application of S-ABA at concentrations 0 (control), 25, 50, 75 mg L⁻¹ two weeks before anticipated harvest. Quality attributes of persimmon fruit were subjected to evaluation at one and two weeks …

Social Relational Notions Of Successful Aging: Contesting Dominant Individualized Conceptions Of Successful Aging By Examining Migrant Intergenerational Lived Experiences, Hien Thi Nguyen, Loretta Baldassar, Raelene Wilding, Bronte Jones

Research outputs 2022 to 2026

Background and Objectives: Critiques of the concept of successful aging (SA) include attention to its foundation on an individualized western medical approach that emphasizes personal choice, agency, and lifestyle. This paper aims to examine how individual notions of SA can be linked to, and co-constituted by, relational and intergenerational notions of personhood within the broader socioeconomic, familial, and cultural contexts of migration. Research Design and Methods: Qualitative research was conducted in Australia (2020–2021) with 42 Vietnamese migrants using ethnographic interviews and participant observation. Data analysis applied inductive reasoning and intersectional analysis to investigate the notion of SA from the perspectives …

Assessment Practices For Dietetic Students: An Updated Systematic Review (2017–2024), Janica Jamieson, Claire Palermo, Margaret Hay, Simone Gibson

Research outputs 2022 to 2026

Aim: Evaluate assessment practices and outcomes for dietetic students and compare findings with those from a previous systematic review. Methods: A systematic review was conducted whereby four databases (MEDLINE, Embase, Cumulative Index in Nursing and Allied Health Literature, and Education Resources Information Centre) were searched on 11 October 2023 with terms related to dietetics, students, and assessment. The search was repeated on 8 January 2025 to identify new publications. Eligibility criteria were primary research published after 1 June 2017 reporting at least one assessment method for dietetic students with an assessment-related outcome. Assessment practices and outcomes were evaluated using Miller's …

The Association Of Cognitive Task Scores With Energy Intake Measurement Error From Technology-Assisted 24 Hr Recalls, Clare Whitton, Barbara A. Mullan, Satvinder S. Dhaliwal, Richard Norman, Carol J. Boushey, Clare E. Collins, Megan E. Rollo, Deborah A. Kerr

Research outputs 2022 to 2026

Measurement error undermines the accuracy of dietary intake data. The 24-hour dietary recall (24HR) is the standard data collection method in nutrition surveillance. Several neurocognitive processes underpin the act of recall, and individuals differ in their performance of these processes. This study aimed to investigate whether variation in neurocognitive processes, measured using four cognitive tasks, was associated with variation in measurement error of 24HRs. Participants (n 139) completed the Trail Making Test, the Wisconsin Card Sorting Test, the Visual Digit Span, and the Vividness of Visual Imagery questionnaire. During a controlled feeding study, participants completed three technology-assisted 24HR; the Automated …

How Young Migrants Perceive School Health Education In Sweden, D. Barker, A. Caldeborg, M. Quennerstedt, Valeria Varea

Research outputs 2022 to 2026

The aim of this paper is to provide insights into how young people who have been forced to migrate perceive school health education. Eighteen individuals aged 15–19 years (10 females, 8 males, average age 16.9 years) took part in either focus group interviews (n = 7) or individual interviews (n = 1). Participants were first presented with short scenarios concerning health education and were invited to use these scenarios as starting points to discuss their own experiences of health education. Participants were then presented with a collection of photographs that portrayed people displaying broad dimensions of health. Participants were asked …

Focus On Frailty: Co-Designing Digital Frailty Education With Healthcare Students, Kristiana Ludlow, Sarah Martin, Benignus Logan, Ruth E. Hubbard, Nicola Warren, Olivia Gallagher, Bonnie K. Kwok, Rosemary Saunders

Research outputs 2022 to 2026

Introduction: Frailty is prevalent in hospitals and is associated with adverse events and poor health outcomes. In Australia, there is a need for co-designed, multidisciplinary, and contextually relevant frailty education to improve healthcare students’ understanding and knowledge of frailty within the hospital setting. Objective: This study aimed to i) explore healthcare students’ understanding of frailty and their experiences with patients who are frail, and ii) seek healthcare students’ design ideas for the content of a new digital frailty education course.

Methods: Participants were university students enrolled in a health-related degree. Online focus groups and interviews were conducted between August and …

Implementing Gross National Happiness In Bhutan As A Development Model And Governance Tool – Perspectives Of Policy Influencers, Tashi Dorji, Angus Morrison-Saunders, David Blake

Research outputs 2022 to 2026

Bhutan’s development philosophy of Gross National Happiness (GNH) prioritises the collective wellbeing of its people over economic growth through a multidimensional index that informs policy. While GNH has received global recognition, persistent challenges in conceptual clarity and practical implementation are argued and debated. This qualitative study examines the role and utility of GNH as a development model and its implementation as a multifaceted governance tool in Bhutan. The findings reveal that GNH is conceptualised in diverse ways, ranging from personal happiness to a more generic communal philosophy. While its strengths lie in its culturally grounded framework, key limitations include a …

Applying Hybrid Coding And Reflexivity In Qualitative Content Analysis: An Exemplar, Kunwar Kaur, Ma’En Zaid Abu-Qamar, Amineh Rashidi, Nilufeur Mckay, Rosemary Saunders

Research outputs 2022 to 2026

Qualitative Content Analysis (QCA) is a widely used method in nursing research for analysing textual data. Numerous authors have provided comprehensive explanations of this approach, including step-by-step guidelines. The coding methods employed in QCA are typically categorised as deductive, inductive, or a combination of both, often referred to as the abductive or hybrid technique. However, the hybrid coding technique remains under-utilised within nursing research. Further, trustworthiness, a cornerstone of qualitative research, has been extensively discussed in the literature, with reflexivity identified as a key component of ensuring rigor and credibility. This paper presents an example from nursing research where a …

Determining Space Requirements For Small And Sick Newborns And Their Mothers In Health Facilities: A Systematic Review, Natalie Strobel, Georgia Whisson, Derek Swe, Rajesh Mehta, Amy Budrikis, Karen Edmond

Research outputs 2022 to 2026

Background There are currently no World Health Organization and United Nations Children Fund benchmarks or ‘norms’ for scaling up small and sick newborn (SSN) service delivery in health facilities in low- and middle-income countries (LMICs). Specifically, there is limited evidence on optimal bed space requirements in SSN units such as special care nurseries and neonatal intensive care units (NICUs). Through this systematic review, we aimed to gather evidence on the optimal space requirements needed for SSNs and their mothers in health facilities, particularly at level 2 district hospitals. Methods We included simulation, experimental, and observational studies, as well as guidelines …

Development And Characterization Of Sustainable Coal–Biomass Briquettes Of Sub-Bituminous Coal And Levistona Chinensis Biomass, Amad Ullah Khan, Borhen Louhichi, Muhammad Abas, Muhammad Saleem, Nashmi H. Alrasheedi, Farida Anjum, Aamer Sharif

Research outputs 2022 to 2026

The increasing demand for sustainable energy solutions has driven the exploration of alternative fuels, such as coal–biomass briquettes, which combine the benefits of both coal and renewable biomass sources. This study focuses on the development and characterization of sustainable coal–biomass briquettes made from sub-bituminous coal (SubC) and Levistona chinensis seed biomass, with the aim of reducing environmental impact and enhancing combustion properties. Briquettes were produced by varying the coal-to-biomass ratios (90:0–0:90), with 10% corn starch used as a binder. Proximate analysis revealed that increasing biomass content raised moisture (5.85%–14.25%) and volatile matter (VM; 24.75%–32.5%), while reducing ash (15.75%–3.39%) and fixed …

Dissemination And Implementation Of Injury Prevention Interventions: A Scoping Review For The Female, Woman And Girl Athlete Injury Prevention (Fair) Consensus, Brooke E. Patterson, Carly D. Mckay, Meghan L. Critchley, Destiny Lutz, Sallie M. Cowan, Nicholas Kolesky, Vanda White, Allison M. Ezzat, Andrew G. Ross, William M. Adams, Eva Ageberg, Clare L. Ardern, Marelise Badenhorst, Molly Coventry, Marc Olivier Dubé, Stacey Emmonds, Libby J. Gracias, K. Alix Hayden, Hanna Lindblom, Merete Møller, Christine Holm Moseid, Nancy Harrington, Dai Sugimoto, Evert Verhagen, Kate K. Yung, Phathokuhle C. Zondi

Research outputs 2022 to 2026

Objective: To synthesise evidence related to the dissemination and implementation (D&I) of injury prevention interventions for female, woman and/or girl (female/woman/girl) athletes. Design Scoping review. Data sources MEDLINE, APA PsycInfo, Cochrane Databases for Systematic Review, Cochrane Central Register for Controlled Trials Registry, EMBASE, CINAHL, SPORTDiscus, ERIC, ProQuest Dissertation and Theses Global. Eligibility Primary research including ≥25% female/woman/girl athletes of any age or people working with them (eg, coaches), participating in sports competition and/or performance, were eligible. Papers reporting D&I outcomes (eg, coach knowledge, adoption and maintenance) related to an injury prevention intervention and/or a factor (eg, coach beliefs) associated with …

Analysing The Behaviour Change Techniques In An Effective Food Literacy Program To Inform Future Program Design, Lucy M. Butcher, Caylah Batt, Sophie Royce, Eamon Barron, Roslyn Giglia, Andrea Begley

Research outputs 2022 to 2026

Aim: Food literacy programs aim to improve food related skills and knowledge and are selected Governments as a strategy to address dietary intakes at a community level. The purpose of this research is to identify behaviour change techniques in a food literacy program, which were assessed by the achievement of participant goals related to food literacy and dietary behaviour changes. Methods: Consensus methods were applied to map behaviour change techniques to an adult food literacy program. A second phase investigation applied content analysis of participant process evaluation data (collected between 2016 and June 2021) to align target behaviours and behaviour …

An Anti-Junk Food Ad From A Sports Commercial Break Reduced Junk Food Consumption Inclinations, Yet Junk Food Ads Had Minimal To No Impact, Ross C. Hollett, Julia Butt, Brennen Mills, Stephanie L. Godrich, Gina S.A. Trapp, Amanda Devine

Research outputs 2022 to 2026

Background: In Australia, there are concerns that unrestricted junk food advertising during sports broadcasts increases short-term junk food consumption among viewers. Therefore, the present study aimed to estimate the impact of junk food and anti-junk food advertising on consumption inclinations. Methods: We conducted a content analysis across a sample (N = 16) of Australian Football League (AFL) and National Rugby League (NRL) matches to determine the prevalence of junk food and anti-junk food advertising video clips. We also exposed participants (N = 428) to a single randomly selected junk food advertisement or a single anti-junk food advertisement and measured the …

Associations Of Vegetable And Potato Intakes With Markers Of Type 2 Diabetes Risk In The Ausdiab Cohort, Pratik Pokharel, Lauren C. Blekkenhorst, Catherine P. Bondonno, Kevin Murray, Simone Radavelli-Bagatini, Dianna J. Magliano, Robin M. Daly, Jonathan E. Shaw, Joshua Lewis, Jonathan M. Hodgson, Nicola P. Bondonno

Research outputs 2022 to 2026

Context: The associations of vegetable and potato intakes with type 2 diabetes (T2D) appear to be nuanced, depending on vegetable types and preparation method, respectively.

Objective: We investigated the associations of total vegetable, vegetable subgroup, and potato intakes with (1) markers of T2D at baseline and (2) incident T2D cumulative over a 12-year follow-up period in Australian adults.

Methods: Using data from the Australian Diabetes, Obesity and Lifestyle Study, intakes of vegetables and potatoes were assessed via a food frequency questionnaire at baseline. Associations between vegetable intake and (1) fasting plasma glucose (FPG), 2-hour postload plasma glucose (PLG), updated homeostasis …

High Diversity Of Dietary Flavonoid Intake Is Associated With A Lower Risk Of All-Cause Mortality And Major Chronic Diseases, Benjamin H. Parmenter, Alysha S. Thompson, Nicola P. Bondonno, Amy Jennings, Kevin Murray, Aurora Perez-Cornago, Jonathan M. Hodgson, Anna Tresserra-Rimbau, Tilman Kühn, Aedín Cassidy

Research outputs 2022 to 2026

Higher habitual intakes of dietary flavonoids have been linked with a lower risk of all-cause mortality and major chronic disease. Yet, the contribution of diversity of flavonoid intake to health outcomes remains to be investigated. Here, using a cohort of 124,805 UK Biobank participants, we show that participants who consumed the widest diversity of dietary flavonoids, flavonoid-rich foods and/or specific flavonoid subclasses had a 6–20% significantly lower risk of all-cause mortality and incidence of cardiovascular disease, type 2 diabetes, cancer, respiratory disease and neurodegenerative disease. Furthermore, we report that both quantity and diversity of flavonoids are independent predictors of mortality …

Increased Nitrate Intake From Beetroot Juice Over 4 Weeks Changes The Composition Of The Oral, But Not The Intestinal Microbiome, Rebeka Fejes, Joana Séneca, Petra Pjevac, Martin Lutnik, Stefan Weisshaar, Nina Pilat, Romy Steiner, Karl Heinz Wagner, Richard J. Woodman, Catherine P. Bondonno, Jonathan M. Hodgson, David Berry, Michael Wolzt, Oliver Neubauer

Research outputs 2022 to 2026

Inorganic dietary nitrate, metabolized through an endogenous pathway involving nitrate reducing bacteria, improves cardiovascular health, but its effects on the oral and intestinal microbiomes of older adults with treated hypertension are unknown. Our study investigated the effects of nitrate from beetroot juice on the oral and intestinal microbiomes of this population. A randomized, double-blind, placebo-controlled crossover trial was conducted with 15 participants (age range: 56–71 years), who consumed nitrate-rich or nitrate-depleted (placebo) beetroot juice for 4 weeks. The oral microbiome analysis revealed an increase in Neisseria and a decrease in Veillonella relative abundance (for both, PERMANOVA p < 0.001), with no significant changes in the intestinal microbiome composition. Our findings suggest that an increased dietary nitrate intake from a vegetable source may selectively modulate the oral microbiome and promote an increased abundance of nitrate-reducing species, which was previously associated with improved cardiovascular health outcomes.

The Impacts Of Digital Technology Use And Tourism Expenditure On Women’S Family Status: Evidence From China, Jinwei Wang, Juan Hu, Yachen Zhang, Xin Wang, Alastair M. Morrison

Research outputs 2022 to 2026

The status of women is an influential factor in supporting the stable development of families and societies. How to improve women’s status has become a focus in gender studies, with emerging digital technologies and tourism expenditure thought to have potential impacts. This research investigated relationships among digital technology use, tourism expenditure, and women’s family status using survey data from the China Family Panel Studies (CFPS). The impacts were determined through developing baseline regression and stepwise regression models. The main findings were: (1) Digital technology use had a significant and positive effect on women’s family status, and there were differences among …

Diagnostic Accuracy Of Electrocardiogram Algorithms For Differentiating Left From Right Outflow Tract Ventricular Arrhythmia: A Systematic Review And Network Meta-Analysis, Zhuoqiao He, Ming Liu, Pengxiang Ying, Manshu Song, Xuerui Tan

Research outputs 2022 to 2026

Background: Accurate pre-Ablation differentiation between left (LVOT) and right (RVOT) ventricular outflow tract arrhythmias (OTVAs) using ECG algorithms is essential for decision on vascular access and treatment strategy. However, the most reliable ECG algorithm remains unclear. We conducted a systematic review and network meta-Analysis (NMA) to compare the diagnostic accuracy of available algorithms. Methods: We searched MEDLINE, EMBASE and Cochrane databases through 7 May 2025 for studies evaluating ECG algorithms against ablation-confirmed OTVA origin. A Bayesian diagnostic test accuracy NMA was performed to estimate pooled sensitivity, specificity, diagnostic odds ratios (DORs) and a superiority index (S) for each algorithm. Study …

Evaluation Of A Virtual Home Health Heart Failure Program: Mixed Methods Study, Nilufeur Mckay, Rosemary Saunders, Helene Metcalfe, Sue Robinson, Peter Palamara, Kellie Steer, Jeannie Yoo, Miles Ranogajec, Lisa Whitehead, Beverley Ewens

Research outputs 2022 to 2026

Background: Heart failure is a prevalent and debilitating condition, affecting millions globally and imposing a significant burden on patients, families, and health care systems. Despite advancements in medical treatments, the gap in effective, continuous, and personalized supportive care remains glaringly evident. To address this pressing issue, virtual health care services delivered by interdisciplinary teams represent a promising solution. Understanding the outcomes and experience of remote monitoring–enabled interdisciplinary chronic disease management programs can inform resource allocation and health care policy decisions. Objective: The purpose of this study was to evaluate the clinical and behavioral outcomes of patients undertaking a Virtual Home …

Exercise And Inflammation In Female Survivors Of Breast Cancer: Systematic Review And Meta-Analysis With Secondary Mediation Analysis On Body Composition, Francesco Bettariga, Dennis R. Taaffe, Anita Borsati, Alice Avancini, Sara Pilotto, Stefano G. Lazzarini, Pedro Lopez, Luca Maestroni, Umberto Crainich, Enrico Bandini, John P. Campbell, Timothy D. Clay, Daniel A. Galvão, Robert U. Newton

Research outputs 2022 to 2026

Purpose: Inflammation plays a key role in breast cancer recurrence and mortality by promoting tumor progression. Exercise significantly reduces pro-inflammatory markers such as IL-6, TNF-α, and CRP, potentially reducing mortality risk. However, it is yet to be determined whether exercise-induced changes in body composition can modulate inflammatory biomarker responses in the breast cancer setting. Methods: We conducted a secondary mediation analysis based on the findings from our previously published systematic review with meta-analysis. Randomized controlled trials examining the effects of exercise on IL-1β, IL-6, IL-8, IL-10, TNF-α, and CRP and body composition and anthropometry measures such as lean mass (LM), …

Postharvest Aqueous Ozonation Alleviates Chilling Injury By Upregulating Ascorbate-Glutathione (Asa-Gsh) Cycle And Associated Antioxidant Enzymes In Cold-Stored ‘Kensington Pride’ Mango Fruit, Mekhala Dinushi Kananke Vithana, Mahmood Ul Hasan, Hafiz Muhammad Shoaib Shah, Zora Singh

Research outputs 2022 to 2026

Chilling injury (CI) hinders prolonged cold storage of mangoes (Mangifera indica L.). Hence, the influence of postharvest aqueous ozonation (PAO) (1 mg ozone s^{− 1}) of mature green ‘Kensington Pride’ mangoes for 10, 20 and 30 min preceding storage at 5 °C for 21 and 28 d on modulating CI, cell membrane integrity, ascorbate-glutathione (AsA-GSH) cycle, antioxidant enzymes and fruit quality were investigated. Compared to control, 10 min PAO significantly reduced CI index (62.5% and 42.9%), CI incidence (40.5% and 41.4%), weight loss (18.4% and 21.8%) and malondialdehyde (MDA) in peel (61.8% and 71.7%) in 21 and 28 …

Rhetorics Or Business As Usual? A Systematic Review Of The Realities Of Australian Aid Localisation Efforts In The Pacific Region, Mark Opoku Amankwa, Clement Amponsah, Kwadwo Adusei-Asante, Vicki Frances Banham, Portia Nana Ama Brempong

Research outputs 2022 to 2026

While Australia increasingly references aid localisation in its programming, implementation remains donor-driven and structurally resistant to local agency. Comprehensive reviews capturing these realities remain scarce. This study synthesises insights from 150 articles obtained from the Web of Science Database to address this gap. Findings reveal persistent donor-driven, hierarchical approaches that marginalise local voices and hinder locally led development. Skill deficits, inadequate information sharing, and underutilisation of local knowledge further undermine effectiveness. Political agendas, market-led narratives, and funding systems prioritising external contractors exacerbate dependency and power imbalances. Antithetically, meaningful local leadership and culturally tailored programs have aligned aid initiatives with community …

Concept-Based Curriculum: An Evidence-Based Approach To Developing A New Framework For Dietetics Education?, Andrea Begley, Janica Jamieson, Gemma Jenkins, Janeane Dart, Lauren T. Williams, Simone Gibson, Fiona E. Pelly, Hattie H. Wright, Claire Palermo

Research outputs 2022 to 2026

Aims: Concept-based approaches to curricula have been proposed as a solution to this issue, and 56 concepts have been proposed for dietetics curricula. This study aimed to develop a framework for a dietetic concept-based curriculum. Methods: A pragmatic approach was employed by a team of nine experienced Australian dietetic educators. Iterative processes of idea generation, reflection, group discussion, and consensus formation were applied by seven of the academics in a two-day face-to-face workshop and four online meetings to further develop the 56 curriculum concepts previously identified for dietetics by Tweedie et al. The discussions were supported by document analysis and …

Motor Cortex Inhibition And Facilitation Changes Within Two Weeks Of Anterior Cruciate Ligament Reconstruction (Aclr): A Case Series, Colin Sylvester, Ann Maree Vallence, Casey Whife, Peter D'Alessandro, Christopher Latella, Ebonie Rio, Myles C. Murphy

Research outputs 2022 to 2026

Purpose: Anterior cruciate ligament reconstruction (ACLR) can cause arthrogenic muscle inhibition (AMI) or persistent muscle weakness that impairs physical function and return to sport. Deficits in voluntary activation (one method to measure AMI) are thought to contribute to AMI, however, the specific neurophysiological underpinnings remain inconclusive. The primary objective of this study was to explore changes in intracortical excitability (inhibition and facilitation) of the quadriceps representation in the primary motor cortex pre- and post-ALCR. Our secondary objective was to explore changes in hamstrings intracortical excitability pre- and post-ALCR. Methods: Prospective case-series pre-post-ACLR. Single- and paired-pulse transcranial magnetic stimulation (TMS) was …

Association Of High-Sensitivity Cardiac Troponin I Levels Below The Sex-Specific 99th Percentile With Late-Life Dementia: The Perth Longitudinal Study Of Ageing Women, Carlos J. Toro-Huamanchumo, Abadi Kahsu Gebre, Tiago Pecanha, Craig Sale, Wai Lim, Elizabeth Byrnes, Ee Mun Lim, Simon Laws, Kun Zhu, Carl Schultz, Richard L. Prince, Blossom C.M. Stephan, Mario Siervo, Joshua R. Lewis, Marc Sim

Research outputs 2022 to 2026

Background: Elevated high-sensitivity cardiac troponin (hs-cTn) levels are linked with cardiovascular disease and cognitive impairment, both of which are strong risk factors for late-life dementia (LLD). This study examined the association between hs-cTnI levels below the sex-specific 99th percentile for myocardial injury and the incidence of LLD in older women. Methods: 986 community-dwelling women aged ≥70 years without prior LLD and with hs-cTnI < 15.6 ng/L (stratified into quartiles) were included from the Perth Longitudinal Study of Ageing Women. The primary outcome was incident LLD events, including LLD hospitalisation or death, over 14.5 years obtained from linked health records. Associations between hs-cTnI and LLD outcomes were explored using multivariable-adjusted Cox models, as part of restricted cubic splines. Results: At baseline, participants' mean (±SD) age was 75.2±2.7 years. Over 14.5 years of follow-up, LLD events (n=174, 17.7%), hospitalisations (n=155, 15.7%) and deaths (n=68, 6.9%) were recorded. Compared with those in the lowest quartile (Q1, median 3.1 ng/L), women in the highest quartile of hs-cTnI (Q4, median 7.3 ng/L) had a greater risk of developing LLD-related events (adjusted HR: 1.88, 95% CI: 1.22 to 2.91), hospitalisation (adjusted HR: 1.65, 95% CI: 1.04 to 2.64) and death (adjusted HR: 2.27, 95% CI: 1.13 to 4.59), after adjusting for established cardiovascular and dementia risk factors, including apolipoprotein E (APOE) genotype. Conclusion: Among older women, hs-cTnI levels below the sex-specific 99th percentile for myocardial injury were associated with an increased risk of LLD events over 14.5 years. These findings suggest that hs-cTnI may identify older women at higher risk of LLD, capturing both cardiovascular and brain health vulnerability in older age.

Establishment Of Reference Intervals For Serum Immunoglobulin G N-Glycosylation Features In Healthy Chinese Adults: A Nationwide Survey In The Framework Of Predictive, Preventive, And Personalized Medicine, Changyu Liu, Yinghao Wang, Xingang Li, Xiaojia Xu, Ruirui Xu, Cuihong Tian, Zhixian Chen, Xinxia Lu, Yuejin Li, Meng Wang, Zhaoyang Tang, Xueyu Chen, Guoyong Ding, Xuerui Tan, Dong Li, Haifeng Hou, Wei Wang

Research outputs 2022 to 2026

Background: Immunoglobulin G (IgG) N-glycosylation plays a vital role in the pathogenesis of autoimmune disorders, inflammatory diseases, and viral infections. While various models of serum IgG N-glycosylation have been developed to identify individuals at high risk for relevant diseases, reference intervals (RIs) for the levels of IgG N-glycans have not been established yet. Identifying RIs for serum IgG N-glycans closely associated with biological aging and disease risk contributes to predictive, preventive, and personalized medicine (PPPM/3PM), which results in improvement of patients’ outcomes, enhancement of healthcare efficiency, and in reducing burden of chronic diseases. This study is aimed at defining the …

Exercise Parameters To Consider For Achilles Tendinopathy: A Modified Delphi Study With International Experts, Yoann Demangeot, Seth O’Neill, Francis Degache, Amandine Rapin, Umer Asgher, Hakan Alfredson, Rachel Chester, Ruth L. Chimenti, Robert Jan De Vos, Adrian Escriche-Escuder, Kenneth Farnqvist, Bas Habets, Nicola Maffulli, Stig Peter Magnusson, Peter Malliaras, Myles C. Murphy, Craig R. Purdam, Jonathan D. Rees, Ebonie K. Rio, Igor Sancho, Alex Scott, Karin Gravare Silbernagel, Vincent Gremeaux, Francois C. Boyer, Redha Taiar

Research outputs 2022 to 2026

To assess the level of agreement among experts on the heel raise exercise parameters that influence midportion and insertional Achilles tendinopathy (AT) rehabilitation outcomes. An international expert panel in AT rehabilitation was invited to complete a three-round Delphi survey. In the first two rounds, experts were asked to review a pregenerated list of exercise parameters (based on the heel raise exercise) and rate their perceived influence on rehabilitation outcome, using a 5-point Likert scale. For each parameter, consensus criteria for major influence on rehabilitation were (a) median≥4, (b) ≥75% of scoring 4 or 5 and (c) IQR≤1. The third round …

Navigating Complexity In Sustainability And Climate Action: Comparing Participatory Action Research And Developmental Evaluation In Higher Education, Elizabeth J. Cook, Fiona Boyle

Research outputs 2022 to 2026

Purpose: This paper aims to investigate how sustainability and climate action are integrated in higher education through collaborative researchmethodologies. Specifically, it addresses the challenges encountered by those using participatory action research (PAR) and suggests developmental evaluation (DE) as a potentially suitable alternative participatorymethodology in certain contexts.

Design/methodology/approach: A comparative analysis of PAR and DE is conducted, highlighting their strengths and limitations in sustainability and climate action initiatives within higher education. Philosophically grounded in pragmatism, the study draws on existing literature to clarify the theoretical foundations and practical implications of both methodologies, focusing on their application in complex, dynamic environments.

Findings: …

Infant Diet Recommendations Reduce Ige-Mediated Egg, Peanut, And Cow's Milk Allergies, Summer V.M. Walker, Nina D'Vaz, Rachelle A. Pretorius, Johnny Lo, Claus Christophersen, Susan L. Prescott, Debra J. Palmer

Research outputs 2022 to 2026

Background: Meta-analyses of randomized controlled trials have found that introducing eggs and peanuts earlier during infancy reduced egg and peanut allergy risk. Hence, infant feeding advice has dramatically changed from previous recommendations of avoidance to current recommendations of inclusion of common food allergens in infant diets. Objective: To compare the prevalence of IgE-mediated food allergies at 1 year of age between 2 cohorts, before and after infant feeding and allergy prevention guidelines changed. Methods: In cohort 1 (506 infants born 2006-2014), no infant feeding advice was provided to participants. In cohort 2 (566 infants born 2016-2022), when the infants were …

Support For Older People Living With Chronic Life-Limiting Illnesses In Rural Ghana, Barbara Adonteng-Kissi, Obed Adonteng-Kissi

Research outputs 2022 to 2026

Summary: This research aims to address formal support needs of informal caregivers (ICs) in the context of long-term care of older people (OP) living with chronic life-limiting illnesses and examine the relationships of ICs of OP with formal support in rural Ghana. We undertook ethnographic interviews with 15 OP; 15 ICs; and 10 healthcare professionals (HPs) after participatory observations during 6 months of fieldwork. This was supported with daily field notes used to collect the needed data and purposively sampled across Gomoa West District in Ghana. The average age of participants was 76 years. Interviews were recorded and transcribed, using …