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Articles 541 - 570 of 13605

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Preliminary Evidence Of Blood Dna Methylation Changes In Pregnant Women Adhering To A Mediterranean Diet, Grace Tavelli, Nikki Schultz, Joanna Brisbane, Nina Kresoje, Samantha Lodge, Jeremy K. Nicholson, Nicola J. Armstrong, Desiree Silva, Nina D’Vaz, David Martino Mar 2026

Preliminary Evidence Of Blood Dna Methylation Changes In Pregnant Women Adhering To A Mediterranean Diet, Grace Tavelli, Nikki Schultz, Joanna Brisbane, Nina Kresoje, Samantha Lodge, Jeremy K. Nicholson, Nicola J. Armstrong, Desiree Silva, Nina D’Vaz, David Martino

Research outputs 2022 to 2026

Background/Objectives: Consumption of a Mediterranean diet (MD) has been associated with reduced incidence of non-communicable diseases and reduced overall mortality, with epigenomic effects representing plausible mediators. The aim of this pilot study was to explore potential epigenetic associations between DNA methylation markers in blood and adherence to an MD in pregnancy. Methods: Fifty-two pregnant women with high or low adherence to an MD throughout pregnancy, who participated in the BioMood ORIGINS study, were selected using an extremes-of-exposure design. DNA methylation (DNAm) profiles from whole blood were generated using the TWIST human methylome panel. We conducted both genome-wide and candidate gene-based …

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Seeing Voices: A Dynamic, Interprofessional Approach To Teaching Performing Arts And Speech-Language Pathology Students About Vocal Anatomy And Physiology, Deborah Hersh, Luzita Fereday, Fiona Palmer, David Hall, Pedro Amarante Andrade, Priscilla Cornelius, Charn Nang, Jane White Mar 2026

Seeing Voices: A Dynamic, Interprofessional Approach To Teaching Performing Arts And Speech-Language Pathology Students About Vocal Anatomy And Physiology, Deborah Hersh, Luzita Fereday, Fiona Palmer, David Hall, Pedro Amarante Andrade, Priscilla Cornelius, Charn Nang, Jane White

Research outputs 2022 to 2026

Objectives: Seeing Voices was an interprofessional, technology-enabled, large-scale, teaching and learning event developed to address the need to improve voice students’ knowledge of laryngeal anatomy and physiology toward understanding and maintaining vocal health. Seeing Voices trialed a novel interprofessional educational approach, collected both quantitative and qualitative data about student experiences of laryngostroboscopic examination, and built a databank of laryngeal recordings for future student learning. Methods: Seeing Voices involved two 3-hour seminars in a large, university lecture space, run by an interprofessional team (speech-language pathologists, vocal coach, Ear Nose and Throat consultant) with quality equipment projecting laryngeal images to large screens …

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Evaluation Of Sanafoam Vaporooter Ii Stress On Activated Sludge Performance For Carbonaceous Removal And Nitrification, Ensiyeh Taheri, Ali Fatehizadeh, John Nazimek, Mustafa Nabi, Wayne Bagg, Amir Razmjou, Paul Nolan, Ratish Permala, Mehdi Khiadani Mar 2026

Evaluation Of Sanafoam Vaporooter Ii Stress On Activated Sludge Performance For Carbonaceous Removal And Nitrification, Ensiyeh Taheri, Ali Fatehizadeh, John Nazimek, Mustafa Nabi, Wayne Bagg, Amir Razmjou, Paul Nolan, Ratish Permala, Mehdi Khiadani

Research outputs 2022 to 2026

Root intrusion control in sewer pipelines often relies on chemical herbicides, yet their unintended impacts on downstream biological treatment remain underexplored. This study investigated the effects of Sanafoam Vaporooter II (SVII) on carbon removal and nitrification in activated sludge reactors (ASRs) under long-term operation. Two parallel bench-scale ASRs were installed and operated at Subiaco municipal wastewater treatment plant in Perth, Western Australia: one was exposed to incremental SVII concentrations (1–3000 mg/L), while the other served as an unamended control. Stoichiometric analysis revealed stable organic matter removal across all SVII doses. In contrast, nitrification decreased progressively at concentrations exceeding 128 mg/L. …

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Mass Cytometry Workflow To Achieve High-Dimensional Immunophenotyping In Resource-Limited Or Decentralized Environments, Natalie Smith, Michael Cohen, Lauren Tracey, Julie Alipaz, Christina Loh, David King, Neha Pulyani, Rebecca Auzins, Elin Gray, Sandra Taylor, Rajat Rai, Steven Kao, Barbara Fazekas De St Groth, Helen Mcguire Mar 2026

Mass Cytometry Workflow To Achieve High-Dimensional Immunophenotyping In Resource-Limited Or Decentralized Environments, Natalie Smith, Michael Cohen, Lauren Tracey, Julie Alipaz, Christina Loh, David King, Neha Pulyani, Rebecca Auzins, Elin Gray, Sandra Taylor, Rajat Rai, Steven Kao, Barbara Fazekas De St Groth, Helen Mcguire

Research outputs 2022 to 2026

Globally, regional and remote communities are burdened by both an increased prevalence and worse prognosis of many infectious and chronic diseases. However, largely owing to logistical challenges, these communities are under-represented in clinical trials and research studies. As individuals from rural communities experience unique environmental exposures and risk factors for disease, immune phenotyping data collected from metropolitan populations may not be broadly generalizable. To address this, we present a workflow that enables the inclusion of resource-limited sites in high-parameter mass cytometry studies. In this approach, whole blood (WB) or peripheral blood mononuclear cells (PBMCs) are collected, stained fresh for surface …

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Digital Pain Assessment: Patient And Family Perspectives, Rosemary Saunders, Kate Crookes, Kaoru Nosaka, Olivia Gallagher, Jeff Hughes, Caroline Bulsara, Max K. Bulsara, Seng Giap Marcus Ang, Beverley Ewens, Sue Haydon, Karla Seaman, Renée Graham, Debra Scaini, Karen Gullick, Michelle Gay, Christopher Etherton-Beer, Renée Graham Mar 2026

Digital Pain Assessment: Patient And Family Perspectives, Rosemary Saunders, Kate Crookes, Kaoru Nosaka, Olivia Gallagher, Jeff Hughes, Caroline Bulsara, Max K. Bulsara, Seng Giap Marcus Ang, Beverley Ewens, Sue Haydon, Karla Seaman, Renée Graham, Debra Scaini, Karen Gullick, Michelle Gay, Christopher Etherton-Beer, Renée Graham

Research outputs 2022 to 2026

Background/Objectives: Pain is a common symptom for hospitalised older adults. Pain is not always adequately assessed, which can lead to inadequate pain management and adverse patient outcomes. Thus, new technology-driven pain assessment tools have been developed; however, little is known about patients’ and families’ experiences of nurses using them in acute care. This study aimed to explore the perspectives of older adult inpatients and their families’ regarding nurses’ use of the digital technology-driven pain assessment application PainChek® Universal. Methods: A survey was undertaken as part of a stakeholder evaluation of a randomised control trial exploring the effectiveness of nurse-led …

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Graph Convolution Neural Network And Deep Q-Network Optimization-Based Intrusion Detection With Explainability Analysis, Kelvin Mwiga, Mussa Dida, Leandros Maglaras, Ahmad Mohsin, Helge Janicke, Iqbal H. Sarker Mar 2026

Graph Convolution Neural Network And Deep Q-Network Optimization-Based Intrusion Detection With Explainability Analysis, Kelvin Mwiga, Mussa Dida, Leandros Maglaras, Ahmad Mohsin, Helge Janicke, Iqbal H. Sarker

Research outputs 2022 to 2026

As networks expand in size and complexity, coupled with an exponential increase in intrusions on network and IoT systems, this leads to traditional models failing to capture increasingly intricate correlations among network components accurately. Graph Convolution Networks (GCNs) have recently acquired prominence for their capacity to represent nodes, edges, or entire graphs by aggregating information from adjacent nodes. However, the correlations between nodes and their neighbours, as well as related edges, differ. Assigning higher weights to nodes and edges with high similarity improves model accuracy and expressiveness. In this paper, we propose the GCN-DQN model, which integrates GCN with a …

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Machine Learning-Based Upscaling Of Rock Permeability From Pore Scale To Core Scale: Effect Of Training Dataset Size And Sub-Core Volumes, Yaotian Guo, Fei Jiang, Takeshi Tsuji, Yoshitake Kato, Mai Shimokawara, Lionel Esteban, Mojtaba Seyyedi, Marina Pervukhina, Maxim Lebedev, Ryuta Kitamura Mar 2026

Machine Learning-Based Upscaling Of Rock Permeability From Pore Scale To Core Scale: Effect Of Training Dataset Size And Sub-Core Volumes, Yaotian Guo, Fei Jiang, Takeshi Tsuji, Yoshitake Kato, Mai Shimokawara, Lionel Esteban, Mojtaba Seyyedi, Marina Pervukhina, Maxim Lebedev, Ryuta Kitamura

Research outputs 2022 to 2026

Permeability characterizes the capacity of porous formations to conduct fluids, thereby governing the performance of carbon capture, utilization, and storage (CCUS), hydrocarbon extraction, and subsurface energy storage. A reliable assessment of rock permeability is therefore essential for these applications. Direct estimation of permeability from low-resolution CT images of large rock samples offers a rapid approach to obtain permeability data. However, the limited resolution fails to capture detailed pore-scale structural features, resulting in low prediction accuracy. To address this limitation, we propose a convolutional neural network (CNN)-based upscaling method that integrates high-precision pore-scale permeability information into core-scale, low-resolution CT images. In …

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Psychosocial Determinants Of Hand Hygiene Practices Among Children And Adolescents Living With Hiv In The Northern City Of Malawi, Balwani Chingatichifwe Mbakaya, Maggie Zgambo, Richard Moyo, Paul Uchizi Kaseka, Obed Nkhata, Fatch Kalembo Feb 2026

Psychosocial Determinants Of Hand Hygiene Practices Among Children And Adolescents Living With Hiv In The Northern City Of Malawi, Balwani Chingatichifwe Mbakaya, Maggie Zgambo, Richard Moyo, Paul Uchizi Kaseka, Obed Nkhata, Fatch Kalembo

Research outputs 2022 to 2026

Background: The common cause of death in HIV and AIDS patients are opportunistic infections such as diarrhoea, acute respiratory infections, and skin conditions. Many of these infections are spread through contaminated hands. Therefore, this study aimed at exploring hand hygiene practices among HIV positive children and adolescents in Mzuzu City, Malawi. Methodology: A cross-sectional study was used to collect data from children and adolescents living with HIV (aged between 9 and 18 years) WHO were attending teen clubs in Mzuzu City. Data were analysed using Stata 17. Chi-Square and logistic regression analysis were used to examine the association among multiple …

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Comprehensive Review Of Lithium Extraction Processes With Economic And Environmental Analysis, Shayan Abrishami, Maryam Gonbadi, Yasaman Boroumand, Mahsa Golmohammadi, Mehdi Narimani, Amin Sarmadi, Chase Matthews, Humberto Estay, Mehdi Khiadani, Amir Razmjou Feb 2026

Comprehensive Review Of Lithium Extraction Processes With Economic And Environmental Analysis, Shayan Abrishami, Maryam Gonbadi, Yasaman Boroumand, Mahsa Golmohammadi, Mehdi Narimani, Amin Sarmadi, Chase Matthews, Humberto Estay, Mehdi Khiadani, Amir Razmjou

Research outputs 2022 to 2026

The growing need for lithium, primarily driven by the expanding electric car market and increasing energy storage requirements, has created a significant demand for sustainable and efficient lithium extraction techniques. This comprehensive review examines the current state and prospects of lithium extraction technologies from both hard-rock and brine sources, offering an enviro-economic perspective on various production methods. While several reviews have attempted to cover lithium extraction in various aspects, our work specifically focuses on the processes of lithium extraction from different sources. We systematically evaluate traditional hard-rock extraction processes, including sulfating, alkali, chlorination, and carbonizing methods, detailing their mechanisms, efficiencies, …

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Remnant Cholesterol And Atherosclerotic Cardiovascular Disease Risk In Populations With Different Low-Density Lipoprotein Cholesterol Elevations: A Prospective Cohort Study, Hong Zheng, Guanlin Chen, Zhenyu Huo, Yulong Lan, Yuxian Wang, Peng Fu, Weiqiang Wu, Haixiang Zheng, Kuangyi Wu, Zegui Huang, Dan Wu, Shouling Wu, Youren Chen Feb 2026

Remnant Cholesterol And Atherosclerotic Cardiovascular Disease Risk In Populations With Different Low-Density Lipoprotein Cholesterol Elevations: A Prospective Cohort Study, Hong Zheng, Guanlin Chen, Zhenyu Huo, Yulong Lan, Yuxian Wang, Peng Fu, Weiqiang Wu, Haixiang Zheng, Kuangyi Wu, Zegui Huang, Dan Wu, Shouling Wu, Youren Chen

Research outputs 2022 to 2026

Background: Low-density lipoprotein cholesterol (LDL-C) and remnant cholesterol (RC) are risk factors for atherosclerotic cardiovascular disease (ASCVD). However, the extent to which differences in RC levels affect ASCVD risk in populations with varying degrees of LDL-C elevation remains unclear. This study aimed to investigate whether RC can provide additional risk stratification value across different sexes, ages, and elevated LDL-C statuses. Methods: This study included 12 743 elevated LDL-C participants (LDL-C ≥3.4 mmol/L) and 50 073 age- and sex-matched non-elevated LDL-C controls from the Kailuan Study. Elevated LDL-C participants were categorized by RC levels into <0.5, 0.5 to <1.0, and ≥1.0 mmol/L subgroups. Kaplan-Meier curves and Cox proportional hazards models were used to assess the relationship between RC levels and ASCVD risk across different sexes, ages, and high LDL-C statuses. Results: During a median follow-up of 12.8 years, 1686 elevated LDL-C participants (13.2%) and 5252 non-elevated LDL-C participants (10.5%) developed ASCVD. In the borderline-high LDL-C group (3.4 ≤ LDL-C < 4.1 mmol/L), those with the lowest RC levels showed no significant risk difference compared with controls (hazard ratio [HR], 1.03 [95% CI, 0.93-1.13]), and this pattern remained consistent across different sexes and ages. In contrast, in the high LDL-C group (LDL-C ≥4.1 mmol/L), even when RC was at the lowest level, ASCVD risk remained significantly higher than that of controls (HR, 1.20 [95% CI, 1.02-1.41]). CONCLUSIONS: In the borderline-high LDL-C population, those with the lowest RC levels showed no significant risk difference compared with controls, and this pattern remained consistent across different sexes and age subgroups. In the high LDL-C population, even when RC was at the lowest level, ASCVD risk remained significantly higher than that of controls.

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Emerging Trends In Photocatalyst-Based Metal-Organic Frameworks For Pfas Degradation, Ahmad Najafidoust, Roham Ghanbari, Javad Farahbakhsh, Ratish Permala, Stefan Iglauer, Masoumeh Zargar Feb 2026

Emerging Trends In Photocatalyst-Based Metal-Organic Frameworks For Pfas Degradation, Ahmad Najafidoust, Roham Ghanbari, Javad Farahbakhsh, Ratish Permala, Stefan Iglauer, Masoumeh Zargar

Research outputs 2022 to 2026

Per- and polyfluoroalkyl substances (PFAS) are highly persistent pollutants in the environment that pose significant health hazards due to their strong chemical resilience and widespread industrial use. Traditional treatment techniques, such as adsorption and reverse osmosis, often struggle with drawbacks like high energy requirements and limited effectiveness against both short- and long-chain PFAS compounds. Among the innovative degradation methods, photocatalysis has gained attention as a viable solution, especially when coupled with metal-organic frameworks (MOFs). MOFs are particularly suited for this purpose due to their high surface area, customizable structures, and superior light absorption properties. This review highlights the latest developments …

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Perceptions Of Ischaemic Heart Disease Risk Among Indian Migrants In Australia: A Qualitative Study, Kunwar Kaur, Ma'en Zaid Abu-Qamar, Amineh Rashidi, Nilufeur Mckay, Rosemary Saunders Feb 2026

Perceptions Of Ischaemic Heart Disease Risk Among Indian Migrants In Australia: A Qualitative Study, Kunwar Kaur, Ma'en Zaid Abu-Qamar, Amineh Rashidi, Nilufeur Mckay, Rosemary Saunders

Research outputs 2022 to 2026

Background: Ischaemic heart disease (IHD) is a global health issue, with people of Indian origin facing earlier onset and more severe cases, leading to higher mortality at younger ages compared to Western countries. Indian migrants maintain similar risks post-migration. Managing modifiable risk factors and improving risk knowledge and health-seeking behaviours are essential, but research on IHD risk perceptions among Indian migrants is limited. Aim: This study explores how first-generation Indian migrants perceive their IHD risk and the factors influencing these perceptions. Methods: As a component of a mixed- method study, a qualitative descriptive study design was employed to examine study …

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Immediate Skin-To-Skin Contact At Very Preterm Birth And Effect On Infant Socio-Emotional Stress Response And Mother–Infant Cortisol Co-Regulation: Secondary Outcomes From The Randomised Clinical Immediate Parent-Infant Skin-To-Skin Study (Ipistoss), Karoline Lode-Kolz, Siri Lillieskold, Hanne Brit Hetland, Eleonora Mascheroni, Stina Klemming, Hanne Pike, Agnes Linner, Nils J. Bergman, Bjorn Westrup, Ulrika Ådén, Evalotte Morelius, Rosario Montirosso, Wibke Jonas, Siren Rettedal Feb 2026

Immediate Skin-To-Skin Contact At Very Preterm Birth And Effect On Infant Socio-Emotional Stress Response And Mother–Infant Cortisol Co-Regulation: Secondary Outcomes From The Randomised Clinical Immediate Parent-Infant Skin-To-Skin Study (Ipistoss), Karoline Lode-Kolz, Siri Lillieskold, Hanne Brit Hetland, Eleonora Mascheroni, Stina Klemming, Hanne Pike, Agnes Linner, Nils J. Bergman, Bjorn Westrup, Ulrika Ådén, Evalotte Morelius, Rosario Montirosso, Wibke Jonas, Siren Rettedal

Research outputs 2022 to 2026

Objective To explore the effects of immediate parent–infant skin-to-skin contact (iSSC) at very preterm birth on maternal–infant behavioural responses and hypothalamic–pituitary–adrenal (HPA) axis reactivity to age-appropriate socio-emotional stress at 4months corrected age. Design Two secondary outcomes from a multicentre randomised controlled trial with two non-blinded parallel groups. Setting Three Scandinavian neonatal intensive care units, level 2 and level 3. Participants 91 infants born at gestational age 28+0to 32+6 from April 2018 to June 2021. Singletons and twins with a second caregiver present were included, regardless of mode of birth. Higher-order births, infants with congenital infections and major malformations were excluded. …

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Plasma Biomarker Progression Across The Alzheimer's Disease Amyloid Beta And Tau Positron Emission Tomography Trajectories, Rodrigo Cánovas, Christopher J. Fowler, Azadeh Feizpour, Vincent Dóre, Pierrick Bourgeat, Ziad S. Saad, Gallen Triana-Baltzer, Hartmuth C. Kolb, Manu Vandijck, Gwendlyn Kollmorgen, Clara Quijano-Rubio, Jurgen Fripp, Simon Laws, Anthony W. Bannon, Kaj Blennow, Henrik Zetterberg, Stephanie Rainey-Smith, Sulantha Mathotaarachchi, Christopher C. Rowe, Colin L. Masters, James D. Doecke Feb 2026

Plasma Biomarker Progression Across The Alzheimer's Disease Amyloid Beta And Tau Positron Emission Tomography Trajectories, Rodrigo Cánovas, Christopher J. Fowler, Azadeh Feizpour, Vincent Dóre, Pierrick Bourgeat, Ziad S. Saad, Gallen Triana-Baltzer, Hartmuth C. Kolb, Manu Vandijck, Gwendlyn Kollmorgen, Clara Quijano-Rubio, Jurgen Fripp, Simon Laws, Anthony W. Bannon, Kaj Blennow, Henrik Zetterberg, Stephanie Rainey-Smith, Sulantha Mathotaarachchi, Christopher C. Rowe, Colin L. Masters, James D. Doecke

Research outputs 2022 to 2026

Introduction: With increased uptake in disease-modifying treatments for amyloid beta (Aβ) removal, it is important to measure performance of highly sensitive plasma biomarkers to detect the presence of Aβ and tau in cognitively impaired populations. Methods: In this study, we investigated a large set of plasma biomarkers for their capability to predict Aβ and tau positron emission tomography (PET) and their association with increasing Aβ and tau burden. RESULTS: From the biomarkers assessed, tau phosphorylated at threonine 217 (pTau217) showed the largest increases across the full range of Aβ and tau levels. Furthermore, pTau217/Aβ42 had the smallest proportion of participants …

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Taurine Supplementation And Human Heat Tolerance: Mechanisms, Evidence, And Integration With Heat Acclimation, Cooling, And Hydration, Siavash Naddafha, Jeffrey R. Stout, Cassandra Evans Feb 2026

Taurine Supplementation And Human Heat Tolerance: Mechanisms, Evidence, And Integration With Heat Acclimation, Cooling, And Hydration, Siavash Naddafha, Jeffrey R. Stout, Cassandra Evans

Research outputs 2022 to 2026

Heat exposure during strenuous exercise increases core temperature and cardiovascular strain, impairing performance and elevating the risk of heat illness. Standard countermeasures include heat acclimation, cooling, and hydration/electrolyte planning. Taurine is a sulfur-containing amino acid present in excitable tissues and widely used as an oral supplement; emerging human trials suggest it can augment thermoregulation, primarily by enhancing eccrine sweating and evaporative heat loss. This narrative review synthesizes mechanistic and applied evidence on taurine during exercise in hot environments and evaluates potential interactions with acclimation, cooling strategies (pre- and per-cooling), and hydration practices. Across a small number of randomized, mostly double-blind …

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The Impact Of A Structured Training Program On The Depth Perception Of Ab Initio Drone Pilots, John Murray, Steven Richardson, Keith Joiner, Graham Wild Feb 2026

The Impact Of A Structured Training Program On The Depth Perception Of Ab Initio Drone Pilots, John Murray, Steven Richardson, Keith Joiner, Graham Wild

Research outputs 2022 to 2026

Highlights: What are the main findings? First empirical assessment of depth-perception improvement from an official RPAS training program. Demonstrates measurable perceptual-skill gains despite no explicit syllabus objective for depth perception. What are the implications of the main findings? Conducted in authentic operational settings under regulated conditions, ensuring strong external validity. Establishes a validated baseline for future comparative and longitudinal studies on perceptual training effectiveness. Flying remotely requires accurate perception of the environment to ensure safe operation. While remotely piloted aircraft (RPA) bring unique opportunities, they also present new challenges for the pilot, including exercising accurate depth perception. The impact of …

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Reflection On Community-Diversified Influence Maximization In Social Networks, Jianxin Li, Taotao Cai, Ke Deng, Timos Sellis, Feng Xia Feb 2026

Reflection On Community-Diversified Influence Maximization In Social Networks, Jianxin Li, Taotao Cai, Ke Deng, Timos Sellis, Feng Xia

Research outputs 2022 to 2026

To celebrate the 50th Anniversary of the Information Systems Journal, we are delighted to share our research reflections on the article “Community-diversified influence maximization in social networks” published at Information Systems in 2020. Our reflections will highlight the impact of this article on the authors’ research trajectories, its influence on the broader research community, and its contributions to industry practice.

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Comment On ‘Muscle-Specific Strength Better Predicts Physical Performance Decline Than Conventional Metrics: The I-Lan Longitudinal Aging Study’ By Chien Et Al., Ricardo M. Lima, Anthony J. Blazevich Feb 2026

Comment On ‘Muscle-Specific Strength Better Predicts Physical Performance Decline Than Conventional Metrics: The I-Lan Longitudinal Aging Study’ By Chien Et Al., Ricardo M. Lima, Anthony J. Blazevich

Research outputs 2022 to 2026

No abstract provided.

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Getting Edgy: Implications Of Fragmented Seagrass Meadows For Fish Assemblages, Simone Strydom, Kathy Murray, Molly Moustaka, Glenn Hyndes, Shaun Wilson Feb 2026

Getting Edgy: Implications Of Fragmented Seagrass Meadows For Fish Assemblages, Simone Strydom, Kathy Murray, Molly Moustaka, Glenn Hyndes, Shaun Wilson

Research outputs 2022 to 2026

Context: Seagrasses are key marine habitats that are increasingly degraded globally due to anthropogenic disturbances and climate change, compromising the ecosystem services they provide. While seagrass loss is often patchy, the ecological consequences of meadow fragmentation on marine fauna remains unclear. Objectives: This study (1) quantified decadal change in seagrass habitat and fragmentation of the globally important meadows of the Shark Bay World Heritage Area following the 2011 marine heatwave (MHW); and (2) assessed how meadow structure and fragmentation influence fish assemblages. Methods: We integrated in situ seagrass data with seascape metrics derived from habitat maps generated from satellite imagery …

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Regulation Of Autophagy-Mediated Pathways By Diet, Physical Activity, And Sleep In Alzheimer's Disease, Ajish Ariyath, Zoe Mputhia, Christopher Dougherty, Bushra Kaleelur Rahuman, W. M.A.D.Binosha Fernando, Belinda Brown, Samantha L. Gardener, Stephanie R. Rainey-Smith, Ralph Martins, Prashant Bharadwaj Feb 2026

Regulation Of Autophagy-Mediated Pathways By Diet, Physical Activity, And Sleep In Alzheimer's Disease, Ajish Ariyath, Zoe Mputhia, Christopher Dougherty, Bushra Kaleelur Rahuman, W. M.A.D.Binosha Fernando, Belinda Brown, Samantha L. Gardener, Stephanie R. Rainey-Smith, Ralph Martins, Prashant Bharadwaj

Research outputs 2022 to 2026

Alzheimer's disease (AD) is a progressive, age-related, neurodegenerative disorder marked by cognitive decline, memory loss, and accumulation of amyloid beta (Aβ) plaques and tau tangles. A key feature of AD is impaired protein homeostasis, often driven by autophagy dysfunction. Autophagy, a cellular degradation and recycling process, plays a vital role in maintaining neuronal health and is increasingly recognized as a therapeutic target in AD. Lifestyle factors such as diet, physical activity, and sleep can positively influence autophagy and support cognitive function. Intermittent fasting (IF) and calorie restriction (CR) activate autophagy and promote longevity; physical activity enhances cerebral blood flow and …

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Beyond The Hype: Organisational Adoption Of Generative Ai Through The Lens Of The Toe Framework–A Mixed Methods Perspective, Laurie Hughes, Fern Davies, Keyao Li, Senali Madugoda Gunaratnege, Tegwen Malik, Yogesh K. Dwivedi Feb 2026

Beyond The Hype: Organisational Adoption Of Generative Ai Through The Lens Of The Toe Framework–A Mixed Methods Perspective, Laurie Hughes, Fern Davies, Keyao Li, Senali Madugoda Gunaratnege, Tegwen Malik, Yogesh K. Dwivedi

Research outputs 2022 to 2026

It is widely accepted that the impact of Generative Artificial Intelligence (GenAI) has been nothing short of transformational, with tangible impacts on industry, education, healthcare and government. But beyond the headlines, how are organisations actually using GenAI, what are the key challenges experienced by decision makers and has the reality on the ground matched the hype? This study adopts a mixed-methods approach, utilising the Technology-Organisation-Environment (TOE) framework to reveal greater insights to how organisations are adopting GenAI, the drivers that affect decision making and the key challenges associated with greater use of the technology. This research adopts a mixed method …

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Evaluation Of Host-Immune Biomarker Signatures As Multiplex Qpcr Diagnostic Assays: A Pilot Study Toward Meeting Who Target Product Profiles For Tb Diagnosis In India, Harriet N. Garlant, Kalaiarasan Ellappan, Noyal Mariya Joseph, Carrie Turner, Vishnukanth Govindaraj, Saka Vinod Kumar, Sanjeev Kumar, Seshadri S. Vasan, Karen Elizabeth Kempsell Feb 2026

Evaluation Of Host-Immune Biomarker Signatures As Multiplex Qpcr Diagnostic Assays: A Pilot Study Toward Meeting Who Target Product Profiles For Tb Diagnosis In India, Harriet N. Garlant, Kalaiarasan Ellappan, Noyal Mariya Joseph, Carrie Turner, Vishnukanth Govindaraj, Saka Vinod Kumar, Sanjeev Kumar, Seshadri S. Vasan, Karen Elizabeth Kempsell

Research outputs 2022 to 2026

Background: Tuberculosis (TB) remains the leading cause of death from a single infectious agent. Current diagnostic tools are limited, especially in low-resource settings. The World Health Organization's (WHO) Target Product Profiles (TPPs) call for rapid, non-sputum-based diagnostics with high sensitivity and specificity. This study evaluates our previously published TB-associated host-immune biomarkers alongside small-size signatures from other studies, in our previously published non-human primate (NHP) TB infection study dataset (GSE76703) and two previously published human datasets (GSE144127, GSE42834), which include other disease group comparators, including sarcoidosis. These were also evaluated in a small-scale, exploratory qPCR pilot study to assess the feasibility …

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Missed Care Prevalence And Associated Factors In Acute Care Settings: A Systematic Review And Meta-Analysis, Afia Achiaa Sarpong, Lucy Gent, Amanda Towell-Barnard, Diana Arabiat Feb 2026

Missed Care Prevalence And Associated Factors In Acute Care Settings: A Systematic Review And Meta-Analysis, Afia Achiaa Sarpong, Lucy Gent, Amanda Towell-Barnard, Diana Arabiat

Research outputs 2022 to 2026

Aim: The aim of the study was to comprehensively analyse the prevalence and factors associated with missed nursing care in acute care settings. Methods: A systematic review was conducted to estimate the prevalence of missed nursing care, types of activities missed and associated factors in acute care hospital settings. Five electronic databases (CINAHL, Embase, Medline, PubMed and Scopus) were searched from inception to 14th December 2022. Type of missed care and associated factors were classified based on missed care concepts, definition and measurement. Random effects meta-analysis was performed to estimate proportions and levels of types of nursing activities missed. Results: …

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Back-On-Track: Protocol For Randomised Controlled Feasibility Trial Of Behavioural Activation In Farmers With Mood Problems, Alison Kennedy, Richard Gray, Martin Jones, Anna Greene, Lauren Mitchell, Meera Senthuren, Suzy Malseed, Feby Savira, Kelly Barnes, Kate Gunn, Susan Brumby Feb 2026

Back-On-Track: Protocol For Randomised Controlled Feasibility Trial Of Behavioural Activation In Farmers With Mood Problems, Alison Kennedy, Richard Gray, Martin Jones, Anna Greene, Lauren Mitchell, Meera Senthuren, Suzy Malseed, Feby Savira, Kelly Barnes, Kate Gunn, Susan Brumby

Research outputs 2022 to 2026

The mental health of people living in farming communities has been identified as an important public health issue. Cumulative exposure to a range of situational factors contributes to heightened risk of poor mental health and suicide. Access to evidence-based psychological treatments is limited by the availability of skilled mental health professionals. The aim of this trial—co-designed by members of the farming community—is to establish the feasibility of conducting randomised controlled, trial-testing, peer-worker-delivered Behavioural Activation in the farming community. We will undertake a single-blind, parallel group, randomised controlled feasibility trial in rural Australia. People living in farming communities aged over 15 …

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Mechanical Properties And Reproducibility Of One-Part Ambient-Cured Slag And Fly Ash-Based Geopolymer Concrete, Daro Sun, Jessey Lee, Alireza Mohyeddin, Janitha Migunthanna Feb 2026

Mechanical Properties And Reproducibility Of One-Part Ambient-Cured Slag And Fly Ash-Based Geopolymer Concrete, Daro Sun, Jessey Lee, Alireza Mohyeddin, Janitha Migunthanna

Research outputs 2022 to 2026

The cement industry is a major source of anthropogenic CO2 emissions due to its energy-intensive production process and calcination of limestone. Producing one ton of cement emits approximately one ton of CO2, and cement accounts for about 5% to 8% of global CO2 emissions. In this context, cement-less one-part (“just-add-water”) ambient-cured geopolymer concrete (GPC) has gained attention due to its environmental friendliness and practicality for large-scale cast-in-situ construction. However, field adoption remains limited, mainly due to the scarcity of data on mechanical properties and durability, as well as the lack of widely accepted standards and specifications. This paper is part …

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Mining Waste As A Resource In Construction: Applications, Benefits, And Challenges, Chathurika Dassanayake, Nuha S. Mashaan, Daniel Oguntayo Feb 2026

Mining Waste As A Resource In Construction: Applications, Benefits, And Challenges, Chathurika Dassanayake, Nuha S. Mashaan, Daniel Oguntayo

Research outputs 2022 to 2026

Mining activities generate vast quantities of waste each year, including mine tailings, bauxite residue, waste rock, and various metallurgical slags. Although these materials have traditionally been regarded as environmental liabilities, many possess physical and chemical properties that make them promising candidates for use in construction. This review synthesizes recent research on the utilization of major mining waste streams, with particular emphasis on pavement applications and other construction materials. The findings indicate that bauxite residue exhibits both pozzolanic and filler characteristics, demonstrating potential in asphalt mastics, asphalt mixtures, and other construction products. Nonetheless, its widespread adoption is constrained by issues such …

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Overtourism In Bali And Lombok: A Governance And Community Perspective On Challenges And Strategies For Sustainable Development, Rudy Pramono, Juliana Juliana, Meitolo Hulu, Arifin Djakasaputra, Ferry Jie Feb 2026

Overtourism In Bali And Lombok: A Governance And Community Perspective On Challenges And Strategies For Sustainable Development, Rudy Pramono, Juliana Juliana, Meitolo Hulu, Arifin Djakasaputra, Ferry Jie

Research outputs 2022 to 2026

The rapid expansion of tourism in Bali and Lombok has precipitated a state of overtourism, critically challenging their ecological and socio-cultural carrying capacities. This study, conducted between 2023 and 2024, employs a qualitative case study approach to investigate the manifestations of overtourism and the efficacy of prevailing mitigation strategies. Data were collected through 32 in-depth interviews, four focus group discussions, and extensive field observations across key destinations in both islands. The findings reveal that overtourism is not merely a function of high visitor numbers but a symptom of systemic governance failure. Key manifestations include acute environmental degradation, the commodification of …

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Enhancing Solar Energy Harvesting: A Comprehensive Study On Photothermal Conversion In Tin/Mxene-Mof Hybrid Nanofluids, Seyedeh Zahra Haeri, Ali Dashan, Javad Farahbakhsh, Mehdi Khiadani, Bahram Ramezanzadeh, Masoumeh Zargar Feb 2026

Enhancing Solar Energy Harvesting: A Comprehensive Study On Photothermal Conversion In Tin/Mxene-Mof Hybrid Nanofluids, Seyedeh Zahra Haeri, Ali Dashan, Javad Farahbakhsh, Mehdi Khiadani, Bahram Ramezanzadeh, Masoumeh Zargar

Research outputs 2022 to 2026

The growing global energy demand highlights the need for renewable sources like solar energy as a key component of sustainable systems. This study focuses on developing two hybrid nanofluids, TiNML125 and MXML125, for optimizing solar energy harvesting. These nanofluids were synthesized via a solvothermal process, combining NH₂-MIL-125 with plasmonic nanoparticles, titanium nitride (TiN) and MXene (MX). Their thermal conductivity, stability, optical properties, and photothermal efficiency were analyzed. Results showed both nanofluids significantly outperformed single-component ML125, with TiNML125 improving absorption by 40 % and enhancing thermal conductivity. MXML125 demonstrated superior long-term stability, with a 25 % lower zeta potential reduction over …

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Vulnerability Of Marine Megafauna To Global At-Sea Anthropogenic Threats, Michelle Vancompernolle, Juliet Morris, Hannah J. Calich, Jorge P. Rodríguez, Sarah A. Marley, Jessica R. Pearce, Briana Abrahms, Katya Abrantes, André S. Afonso, Alex Aguilar, Andrews Agyekumhene, Tomonari Akamatsu, Susanne Åkesson, Nyimale G. Alawa, Joanna Alfaro-Shigueto, R. C. Anderson, Tycho Anker-Nilssen, Javier A. Arata, Gonzalo Araujo, Martin C. Arostegui, Haritz Arrizabalaga, Chandra P. Salgado Kent Feb 2026

Vulnerability Of Marine Megafauna To Global At-Sea Anthropogenic Threats, Michelle Vancompernolle, Juliet Morris, Hannah J. Calich, Jorge P. Rodríguez, Sarah A. Marley, Jessica R. Pearce, Briana Abrahms, Katya Abrantes, André S. Afonso, Alex Aguilar, Andrews Agyekumhene, Tomonari Akamatsu, Susanne Åkesson, Nyimale G. Alawa, Joanna Alfaro-Shigueto, R. C. Anderson, Tycho Anker-Nilssen, Javier A. Arata, Gonzalo Araujo, Martin C. Arostegui, Haritz Arrizabalaga, Chandra P. Salgado Kent

Research outputs 2022 to 2026

Marine megafauna species are affected by a wide range of anthropogenic threats. To evaluate the risk of such threats, species’ vulnerability to each threat must first be determined. We build on the existing threats classification scheme and ranking system of the International Union for Conservation of Nature (IUCN) Red List of Threatened Species by assessing the vulnerability of 256 marine megafauna species to 23 at-sea threats. The threats we considered included individual fishing gear types, climate-change-related subthreats not previously assessed, and threats associated with coastal impacts and maritime disturbances. Our ratings resulted in 70 species having high vulnerability (v > 0.778 …

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Animal Taxa Threatened By Adverse Fire Regimes In Western Australia: A Synthesis And Outlook, Tim S. Doherty, Mark G. Allen, Karlene Bain, Stephen J. Beatty, Allan H. Burbidge, Renee A. Catullo, Sarah Comer, Ben Corey, Saul J. Cowen, Robert A. Davis, Martin A. Dziminski, J. Anthony Friend, Bruce Greatwich, Mark S. Harvey, Hannah Killian, Michael W. Klunzinger, Damian C. Lettoof, Nicola J. Mitchell, Melinda Moir, Harry A. Moore, David L. Morgan, Ian J. Radford, Michael G. Rix, Tom Vigilante, Adrian F. Wayne, Corey Whisson Feb 2026

Animal Taxa Threatened By Adverse Fire Regimes In Western Australia: A Synthesis And Outlook, Tim S. Doherty, Mark G. Allen, Karlene Bain, Stephen J. Beatty, Allan H. Burbidge, Renee A. Catullo, Sarah Comer, Ben Corey, Saul J. Cowen, Robert A. Davis, Martin A. Dziminski, J. Anthony Friend, Bruce Greatwich, Mark S. Harvey, Hannah Killian, Michael W. Klunzinger, Damian C. Lettoof, Nicola J. Mitchell, Melinda Moir, Harry A. Moore, David L. Morgan, Ian J. Radford, Michael G. Rix, Tom Vigilante, Adrian F. Wayne, Corey Whisson

Research outputs 2022 to 2026

Adverse fire regimes threaten biodiversity, potentially leading to population declines and increased extinction risk. Understanding how varying fire regimes affect threatened species is essential for effective ecosystem management, including in Western Australia where diverse ecosystems are exposed to wildfires, Indigenous burning, and prescribed fire. We compiled and synthesised data on the threat of adverse fire regimes to threatened animal taxa in Western Australia. Using a threat classification scheme, we ranked adverse fire regimes as having either no, low, medium, high, or unknown impact on each taxon. A total of 212 taxa were reviewed, 153 (72%) of which are considered fire-threatened: …

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