Digital Commons Network^™

New Strategy For The Search Of Natural Biologically Active Substances., Vyacheslav Dushenkov, Ilya Raskin

Publications and Research

The modern pharmaceutics actively screens an immense diversity of substances occurring in plants and other natural resources in the search for new effective medicinal agents. The Global Institute for Bioexploration (GIBEX) established by joint efforts of Rutgers University and the University of Illinois (United States) represents the organizational core of international scientific community whose activity is directed towards the search and development of new medicinal preparations from natural raw materials. The basis of GIBEX activity is the transfer of modern screening technologies to countries and geographical regions characterized by remarkable biodiversity. The GIBEX goals are to encourage the search for …

An Interdisciplinary Discussion Of Poverty, Class & Economic Justice, Frances Fox Piven, Stephen Loffredo

City University of New York Law Review

No abstract provided.

Does Congress Have The Power To Limit The President's Conduct Of Detentions, Interrogations And Surveillance In The Context Of War?, Shayana Kadidal

City University of New York Law Review

No abstract provided.

Identification Of A Novel Conserved Mixed-Isoform B56 Regulatory Subunit And Spatiotemporal Regulation Of Protein Phosphatase 2a During Xenopus Laevis Development, Sungmin Baek, Joni M. Seeling

Publications and Research

Background Wnt signaling is a key regulator of development and tumorigenesis. Protein phosphatase 2A (PP2A), which consists of a catalytic C, a structural A, and a regulatory B subunit, plays diverse roles in Wnt signaling through its B56 subunits. B56 is a multigene family encoding for proteins with a conserved core domain and divergent amino- and carboxy-termini. Ectopic B56α and B56γ reduce β-catenin abundance and B56α reduces Wnt-dependent transcription, suggesting that B56α and B56γ inhibit Wnt signaling. In contrast, B56ε is required for Wnt signaling. Knowledge of where and when B56 subunits are expressed during Xenopus development will aid in …

The Ticker, December 10, 2007

The Ticker

The Ticker is the student newspaper of Baruch College. It has been published continuously since 1932, when the Baruch College campus was the School of Business and Civic Administration of the City College of New York.

The Ticker, November 12, 2007

The Ticker

The Ticker is the student newspaper of Baruch College. It has been published continuously since 1932, when the Baruch College campus was the School of Business and Civic Administration of the City College of New York.

The Ticker, November 5, 2007

The Ticker

The Ticker is the student newspaper of Baruch College. It has been published continuously since 1932, when the Baruch College campus was the School of Business and Civic Administration of the City College of New York.

Cell Death In Health And Disease, Richard A. Lockshin, Zahra Zakeri

Publications and Research

Cell death is clearly an important factor in development, homeostasis, pathology and in aging, but medical efforts based on controlling cell death have not become major aspects of medicine. There are several reasons why hopes have been slow to be fulfilled, and they present indications for new directions in research. Most effort has focused on the machinery of cell death, or the proximate effectors of apoptosis and their closely associated and interacting proteins. But cells have many options other than apoptosis. These include autophagy, necrosis, atrophy and stepwise or other alternate means of self-disassembly. The response of a cell to …

A Mutation In Mrh2 Kinesin Enhances The Root Hair Tip Growth Defect Caused By Constitutively Activated Rop2 Small Gtpase In Arabidopsis, Guohua Yang, Peng Gao, Hua Zhang, Shanjin Huang, Zhi-Liang Zheng

Publications and Research

Root hair tip growth provides a unique model system for the study of plant cell polarity. Transgenic plants expressing constitutively active (CA) forms of ROP (Rho-of-plants) GTPases have been shown to cause the disruption of root hair polarity likely as a result of the alteration of actin filaments (AF) and microtubules (MT) organization. Towards understanding the mechanism by which ROP controls the cytoskeletal organization during root hair tip growth, we have screened for CA-rop2 suppressors or enhancers using CA1-1, a transgenic line that expresses CA-rop2 and shows only mild disruption of tip growth. Here, we report the characterization of a …

Adverse Effects Of Accounting, Uniformity On Practice, Education And Research, Shyam Sunder

Publications and Research

No abstract provided.

Novel In Silico Method For Teaching Cytoarchitecture, Cellular Diversity, And Gene Expression In The Mammalian Brain, Raddy L. Ramos, Phoebe T. Smith, Joshua C. Brumberg

Publications and Research

Neuroanatomy can be a challenging topic for undergraduates, making the development of new methods of instruction an important goal of neuroscience educators. In the present report we describe the utility and versatility of the Allen Brain Atlas as a novel tool for instruction of several important anatomical principles of the mammalian central nervous system. Using this digital database, we detail how instructors of laboratory or lecture-based courses can demonstrate cytoarchitecture, cellular diversity, and gene expression profiles of the brain.

Northeast Under/Graduate Research Organization For Neuroscience (Neuron): Our Third New York City Meeting, Sharon Ramos Goyette, Kassandra L. Edinger, Vicki Luine, Jason Young, Cheryl A. Frye

Publications and Research

The NorthEast Under/graduate Research Organization for Neuroscience (N.E.U.R.O.N.) promotes preparation, education, and undergraduate research in Neuroscience. The N.E.U.R.O.N. Conference was initially held at undergraduate institutions primarily in New England. Then, for the previous two years, to broaden its impact and increase diversity, the meeting moved to Hunter College, CUNY, New York. This year represents the first year in which two N.E.U.R.O.N. meetings were held, one in Boston and one in New York City. The following is a report of the New York City meeting which was held at Hunter College on April 28, 2007. Eminent Neuroscientist, Dr. Carol Sue Carter, …

Growth Environment And Sex Differences In Lipids, Bodyshape And Diabetes Risk, Mary Schooling, Tai Hing Lam, G. Neil Thomas, Benjamin J. Cowling, Michelle Heys, Edward D. Janus, Gabriel M. Leung

Publications and Research

Background
Sex differences in lipids and body shape, but not diabetes, increase at puberty. Hong Kong Chinese are mainly first or second generation migrants from China, who have shared an economically developed environment for years, but grew up in very different environments in Hong Kong or contemporaneously undeveloped Guangdong, China. We assessed if environment during growth had sex-specific associations with lipids and body shape, but not diabetes.

Methodology and Principal Findings
We used multivariable regression in a population-based cross-sectional study, undertaken from 1994 to 1996, of 2537 Hong Kong Chinese residents aged 25 to 74 years with clinical measurements of …

The Ticker, September 24, 2007

The Ticker

The Ticker is the student newspaper of Baruch College. It has been published continuously since 1932, when the Baruch College campus was the School of Business and Civic Administration of the City College of New York.

The Ticker, September 4, 2007

The Ticker

The Ticker is the student newspaper of Baruch College. It has been published continuously since 1932, when the Baruch College campus was the School of Business and Civic Administration of the City College of New York.

Perigenual Anterior Cingulate Morphology Covaries With Perceived Social Standing, Peter J. Gianaros, Jeffrey A. Horenstein, Sheldon Cohen, Karen A. Matthews, Sarah M. Brown, Janine D. Flory, Hugo D. Critchley, Stephen B. Manuck, Ahmad R. Hariri

Publications and Research

Low socioeconomic status (SES) increases the risk for developing psychiatric and chronic medical disorders. A stress-related pathway by which low SES may affect mental and physical health is through the perception of holding a low social standing, termed low subjective social status. This proposal implicates overlapping brain regions mediating stress reactivity and socioemotional behaviors as neuroanatomical substrates that could plausibly link subjective social status to health-related outcomes. In a test of this proposal, we used a computational structural neuroimaging method (voxel-based morphometry) in a healthy community sample to examine the relationships between reports of subjective social status and regional gray …

Nothing New: A Small Enterprise Development Project In West Africa, Aaron Barlow, Bronwyn Hughes

Publications and Research

"This article presents a specific strategy for the aid worker wishing to encourage income-generating enterprises followed by an analysis of the initiation of a construction-supplies business in the north of Togo, West Africa in the late 1980s. This article also stresses project assessment as insurance against failure for the aid organization. Together, these can lead to self-sustaining projects and the furthering of real development."

The Ticker, August 27, 2007

The Ticker

The Ticker is the student newspaper of Baruch College. It has been published continuously since 1932, when the Baruch College campus was the School of Business and Civic Administration of the City College of New York.

Evolution Of Dispersal And Life History Strategies – Tetrahymena Ciliates, Else J. Fjerdingstad, Nicolas Schtickzelle, Pauline Manhes, Arnaud Gutierrez, Jean Clobert

Publications and Research

Background Considerable attention has focused on how selection on dispersal and other core life-history strategies (reproductive effort, survival ability, colonization capacity) may lead to so-called dispersal syndromes. Studies on genetic variation in these syndromes within species could importantly increase our understanding of their evolution, by revealing whether traits co-vary across genetic lineages in the manner predicted by theoretical models, and by stimulating further hypotheses for experimental testing. Yet such studies remain scarce. Here we studied the ciliated protist Tetrahymena thermophila, a particularly interesting organism due to cells being able to transform into morphs differing dramatically in swim-speed. We investigated dispersal, …

Novel Research Translates To Clinical Cases Of Schizophrenic And Cocaine Psychosis, João V. Nunes, Patricia A. Broderick

Publications and Research

Pharmacotherapies for schizophrenic and cocaine psychoses are complex but similar because of similarities in their brain neurochemistry and behavioral outcomes. Their neurochemical neuronal mechanisms of action, as shown in preclinical and clinical studies, involve primarily dopaminergic dysfunction and, secondarily, neuroadaptive effects that seem to involve central serotonergic function. Behavioral outcomes of both disorders include hyperactivity and antipsychotic medications can ameliorate psychotic symptoms. Patients with both disorders often arrive at emergency departments and present floridly psychotic with a predominance of positive symptoms, often prompting physicians to select a typical antipsychotic medication such as haloperidol. While this has become conventional wisdom, we …

Comparative Mitochondrial Genomics Of Snakes: Extraordinary Substitution Rate Dynamics And Functionality Of The Duplicate Control Region, Zhi J. Jiang, Todd A. Castoe, Christopher C. Austin, Frank T. Burbrink, Matthew D. Herron, Jimmy A. Mcguire, Christopher L. Parkinson, David D. Pollock

Publications and Research

Background The mitochondrial genomes of snakes are characterized by an overall evolutionary rate that appears to be one of the most accelerated among vertebrates. They also possess other unusual features, including short tRNAs and other genes, and a duplicated control region that has been stably maintained since it originated more than 70 million years ago. Here, we provide a detailed analysis of evolutionary dynamics in snake mitochondrial genomes to better understand the basis of these extreme characteristics, and to explore the relationship between mitochondrial genome molecular evolution, genome architecture, and molecular function. We sequenced complete mitochondrial genomes from Slowinski's corn …

The Ticker, July 9, 2007

The Ticker

The Ticker is the student newspaper of Baruch College. It has been published continuously since 1932, when the Baruch College campus was the School of Business and Civic Administration of the City College of New York.

The Golden Dawn, Carlo Alvaro

Publications and Research

No abstract provided.

The "War On Terror" Through British And International Humanitarian Law Eyes: Comparative Perspective On Selected Legal Issues, David Turns

City University of New York Law Review

No abstract provided.

Utility And Versatility Of Extracellular Recordings From The Cockroach For Neurophysiological Instruction And Demonstration, Raddy L. Ramos, Andrew Moiseff, Joshua C. Brumberg

Publications and Research

The principles of neurophysiology continue to be challenging topics to teach in the context of undergraduate neuroscience education. Laboratory classes containing neurophysiological demonstrations and exercises are, therefore, an important and necessary complement for covering those subjects taught in lecture-based courses. We developed a number of simple yet very instructive exercises, described below, which make use of extracellular recordings from different sensory systems of the cockroach (Periplanta americana). The compendium we developed provides students with hands-on demonstrations of several commonly taught topics of neurophysiology including sensory coding by neural activity.

Genetic Randomization Reveals Functional Relationships Among Morphologic And Tissue-Quality Traits That Contribute To Bone Strength And Fragility, Karl J. Jepsen, Bin Hu, Steven M. Tommasini, Hayden-William Courtland, Christopher Price, Carl J. Terranova, Joseph H. Nadeau

Publications and Research

We examined femora from adult AXB/BXA recombinant inbred (RI) mouse strains to identify skeletal traits that are functionally related and to determine how functional interactions among these traits contribute to genetic variability in whole-bone stiffness, strength, and toughness. Randomization of A/J and C57BL/6J genomic regions resulted in each adult male and female RI strain building mechanically functional femora by assembling unique sets of morphologic and tissue-quality traits. A correlation analysis was conducted using the mean trait values for each RI strain. A third of the 66 correlations examined were significant, indicating that many bone traits covaried or were functionally related. …

¡Escriba! ¡Write! Volume 5, June 2007, Hostos Community College Library

¡Escriba!

No abstract provided.

"Whether Beast Or Human": The Cultural Legacies Of Dread, Locks, And Dystopia., Kevin Frank

Publications and Research

Analyzing the ongoing problem of Caribbean racial exploitation, particularly fear signified through one of the most potent Caribbean symbols, dreadlocks, Kevin Frank offers a paradigm shift in arguing that Medusa's alterity is altered by Rastafarians' snake-like hair, but the transformative power of Rasta dreadlocks is contested through certain cinematic depictions of dread.

A Role For Sperm In Regulation Of Egg-Laying In The Nematode C. Elegans, Marie Mcgovern, Ling Yu, Mary Kosinski, David Greenstein, Cathy Savage-Dunn

Publications and Research

Background In insects and in mammals, male sperm and seminal fluid provide signaling factors that influence various aspects of female physiology and behavior to promote reproductive success and to compete with other males. It is less apparent how important such signaling is in the context of a self-fertile hermaphrodite species. We have addressed this question in the nematode Caenorhabditis elegans, which can reproduce either by hermaphrodite self-fertilization or by male-hermaphrodite mating.

Results We have studied the egg-laying defective mutant, egl-32, and found that the cellular basis of the egl-32 egg-laying phenotype is likely a defect in sperm. First, the time …

Sensory Deprivation Alters Aggrecan And Perineuronal Net Expression In The Mouse Barrel Cortex, Paulette A. Mccrae, Mary M. Rocco, Gail Kelly, Joshua C. Brumberg, Russell T. Matthews

Publications and Research

An important role for the neural extracellular matrix in modulating cortical activity-dependent synaptic plasticity has been established by a number of recent studies. However, identification of the critical molecular components of the neural matrix that mediate these processes is far from complete. Of particular interest is the perineuronal net (PN), an extracellular matrix component found surrounding the cell body and proximal neurites of a subset of neurons. Because of the apposition of thePNto synapses and expression of this structure coincident with the close of the critical period, it has been hypothesized that nets could play uniquely important roles in synapse …