Digital Commons Network^™

Renewing The Oyate; Dakota Language And Cultural Revitalization And Commemorations Of The U.S.-Dakota War, 1962-2012, Deborah Edwards-Anderson

Dissertations and Theses

No abstract provided.

A Briny Crossroads Salt, Slavery, And Sectionalism In The Kanawha Salines, Cyrus Forman

Dissertations and Theses

The Kanawha Salines are a place whose history challenges conventional narratives and popular assumptions about slavery and freedom in the antebellum South. The paradoxical nature of slavery in this locale can be seen in the identity of the first documented people forced to labor in the salt works. A half century before enslaved Africans were imported to this region, European women and their families were kidnapped, enslaved, and marched to the salt mines by Native Americans: “In 1755, the Indians had carried Mary Ingles, her newborn baby, and others as captives....to this spot on the Kanawha to attain a salt …

Art As Dissent In The Midst Of Mexico's Drug War, Ana Lorena Marron Nozari

Dissertations and Theses

No abstract provided.

The Indian Aesthetic In Ninth-Century Japan; A Study Of Foreignness In Early Japanese Esoteric Buddhist Art, Alison Badassano

Dissertations and Theses

No abstract provided.

Climate Change And Developing Countries; Examaning The Motives For Participation In International Negotiations, Nathalie Zapletal

Dissertations and Theses

No abstract provided.

Conflicts Of Soviet Ideology In Sergei Prokofiev's Film Score For Ivan The Terrible, Elizabeth R. Blaufox

Dissertations and Theses

No abstract provided.

Herbert Ponting; Picturing The Great White South, Maggie Downing

Dissertations and Theses

No abstract provided.

John Gay's Trivia And The Beggar's Opera: Capitalism, Identity, And The Lost Eighteenth Century Found, Christina Polizoto

Dissertations and Theses

No abstract provided.

Elephant In The Dark, Eli Samuel

Dissertations and Theses

No abstract provided.

The White Creoles Of Saint Domingue Facing Revolution, Lionel Zami

Dissertations and Theses

No abstract provided.

Sudden Onset, Diane E. Keeney

Dissertations and Theses

No abstract provided.

Sorting Sheep And Goats In Medieval Iceland And Greenland Local Subsistence, Climate Change, Or World System Impacts?, Thomas Mcgovern, Ramona Harrison, Konrad Smiarowski

Publications and Research

Large archaeofaunal collections recovered from Viking Age and Medieval sites in Iceland and Greenland during intensive collaborative fieldwork over the past decade have demonstrated a diverging pattern in sheep and goat (caprine) management after ca. 1200 CE in the two Norse communities. Since Landnám (first settlement), flocks in both places contained a mixture of sheep and goats and survivorship profiles suggest a very mixed milk-meat-wool production strategy. By the late 13^th century Icelandic herds were nearly all sheep, and zooarchaeological evidence suggests an increasing focus on wool production. Greenlandic archaeofauna indicate that farmers maintained the old Viking Age pattern …

Eco-Theatre, R. Murray Schafer, Eleanor James, Sarah Ann Standing

Publications and Research

Born in Sarnia, Ontario, in 1933, and widely considered Canada’s leading living composer, Raymond Murray Schafer is also a librettist, educator, writer, and “soundscape” theorist. Schafer composes for symphonies as well as chamber orchestras, solo instruments (he has even composed a piece for snowmobile), and vocalists. His compositions have played throughout the world. Schafer’s operatic cycle Patria—a masterwork almost forty years in the making—consists of ten episodes, plus a prologue and an epilogue. The prologue The Princess of the Stars and epilogue And Wolf Shall Inherit the Moon (also known as the Wolf Project) comprise an eco-theatre where Schafer places …

Bombing For Justice: Urban Terrorism In New York City From The 1960s Through The 1980s, Jeffrey A. Kroessler

Publications and Research

From the mid-1960s into the 1980s New York City experienced a wave of political violence and urban terrorism. Groups planted bombs, hijacked airliners, and engaged in assassination and attempted assassination to advance political, racial, or nationalist agendas. They included the Jewish Defense League, the Weathermen, the Black Panthers and the Black Liberation Army, FALN and other advocates of Puerto Rican independence, the United Freedom Front, Omega 7 and other anti-Castro Cubans, and Croatian nationalists. Juries often failed to convict these individuals, and others received light sentences. Judges scrutinized police actions for abuses of constitutional rights, and attorneys like William Kunstler …

Review: Digital Humanities Pedagogy: Practices, Principles, And Politics, Stephen Brier

Publications and Research

Review of Digital Humanities Pedagogy: Practices, Principles, and Politics, edited by Brett D. Hirsch, multiple authored collection of articles on the theory as well as the practices and principles of the digital humanities and how DH can and has begun to reshape pedagogy in college teaching and learning.

Agalychnis Dacnicolor—Predation., Víctor H. Jiménez-Arcos, Eric Centenero-Alcala, Leopoldo D. Vázquez Reyes, Christopher Blair, Samuel A. Santa Cruz-Padilla

Publications and Research

No abstract provided.

Inhibition Of Phosphodiesterase10a Attenuates Morphine-Induced Conditioned Place Preference, Ying Mu, Zhaoxiang Ren, Jia Jia, Bo Gao, Longtai Zheng, Eitan Friedman

Publications and Research

Background: Phosphodiesterase (PDE) 10A is selectively expressed in medium spiny neurons of the striatum. Nucleus accumbens (NAc) is a key region that mediates drug reward and addiction-related behaviors. To investigate the potential role of PDE10A in the reinforcement properties of morphine, we tested the effect of MP-10, a selective inhibitor of PDE10A, on acquisition, expression, and extinction of morphine-induced conditioned place preference (CPP).

Results: The results show that 2.5 mg/kg MP-10, administered subcutaneously, significantly inhibited the acquisition of morphine-induced CPP. The same dose of MP-10 alone did not result in the CPP. Moreover, MP-10 did not alter the expression of …

Single-Room Occupancy Housing In New York City: The Origins And Dimensions Of A Crisis, Brian J. Sullivan, Jonathan Burke

City University of New York Law Review

No abstract provided.

Los Efectos De Las Transformaciones Agrícolas En Los Antiguos Países Socialistas: Algunas Consideraciones Para Cuba, Mario A. Gonzalez-Corzo

Publications and Research

Este estudio ofrece una síntesis de los efectos principales de las transformaciones agrícolas en un grupo selecto de antiguos países socialistas de Asia y Europa, tomando en base la importancia de indicadores como la producción física, la productividad laboral y los rendimientos agrícolas, y evalúa algunas consideraciones relevantes en el caso de Cuba. Por razones de espacio, el estudio no incluye otros indicadores de los efectos de las reformas agrícolas como los ingresos rurales, el impacto ambiental y los costos de oportunidad relacionados con la transición. Los países incluidos en el estudio son: China, Vietnam, Rusia, Ucrania, Estonia, La Republica …

Spinal Morphine But Not Ziconotide Or Gabapentin Analgesia Is Affected By Alternative Splicing Of Voltage-Gated Calcium Channel Cav2.2 Pre-Mrna, Yu-Qiu Jiang, Arturo Andrade, Diane Lipscombe

Publications and Research

Presynaptic voltage-gated calcium CaV2.2 channels play a privileged role in spinal level sensitization following peripheral nerve injury. Direct and indirect inhibitors of CaV2.2 channel activity in spinal dorsal horn are analgesic in chronic pain states. CaV2.2 channels represent a family of splice isoforms that are expressed in different combinations according to cell-type. A pair of mutually exclusive exons in the CaV2.2 encoding Cacna1b gene, e37a and e37b, differentially influence morphine analgesia. In mice that lack exon e37a, which is enriched in nociceptors, the analgesic efficacy of intrathecal morphine against noxious thermal stimuli is reduced. Here we ask if sequences unique …

Microfluidic Generated Egf-Gradients Induce Chemokinesis Of Transplantable Retinal Progenitor Cells Via The Jak/Stat And Pi3kinase Signaling Pathways., Uchenna J. Unachukwu, Moira Sauane, Maribel Vazquez, Stephen Redenti

Publications and Research

A growing number of studies are evaluating retinal progenitor cell (RPC) transplantation as an approach to repair retinal degeneration and restore visual function. To advance cell-replacement strategies for a practical retinal therapy, it is important to define the molecular and biochemical mechanisms guiding RPC motility. We have analyzed RPC expression of the epidermal growth factor receptor (EGFR) and evaluated whether exposure to epidermal growth factor (EGF) can coordinate motogenic activity in vitro. Using Boyden chamber analysis as an initial high-throughput screen, we determined that RPC motility was optimally stimulated by EGF concentrations in the range of 20-400 ng/ml, with decreased …

Reductions In Serum Igf-1 During Aging Impair Health Span, Zhenwei Gong, Oran Kennedy, Hui Sun, Yingjie Wu, Garry A. Williams, Laura Klein, Luis Cardoso, Ronald W. Matheny Jr, Gene B. Hubbard, Yuji Ikeno, Roger P. Farrar, Mitchell B. Schaffler, Martin L. Adamo, Radhika H. Muzumdar, Shoshana Yakar

Publications and Research

In lower or simple species, such as worms and flies, disruption of the insulin-like growth factor (IGF)-1 and the insulin signaling pathways has been shown to increase lifespan. In rodents, however, growth hormone (GH) regulates IGF-1 levels in serum and tissues and can modulate lifespan via/or independent of IGF- 1. Rodent models, where the GH/IGF-1 axis was ablated congenitally, show increased lifespan. However, in contrast to rodents where serum IGF-1 levels are high throughout life, in humans, serum IGF-1 peaks during puberty and declines thereafter during aging. Thus, animal models with congenital disruption of the GH/ IGF-1 axis are unable …

Brief Monocular Deprivation As An Assay Of Short-Term Visual Sensory Plasticity In Schizophrenia - "The Binocular Effect", John J. Foxe, Sheralyn Yeap, Victoria M. Leavitt

Publications and Research

Background: Visual sensory processing deficits are consistently observed in schizophrenia, with clear amplitude reduction of the visual evoked potential (VEP) during the initial 50-150 of processing. Similar deficits are seen in unaffected first-degree relatives and drug-naïve first-episode patients, pointing to these deficits as potential endophenotypic markers. Schizophrenia is also associated with deficits in neural plasticity, implicating dysfunction of both glutamatergic and GABAergic systems. Here, we sought to understand the intersection of these two domains, asking whether short-term plasticity during early visual processing is specifically affected in schizophrenia.

Methods: Brief periods of monocular deprivation (MD) induce relatively rapid changes …

Toward Target 2 Of The Global Strategy For Plant Conservation: An Expert Analysis Of The Puerto Rican Flora To Validate New Streamlined Methods For Assessing Conservation Status, James S. Miller, Gary A. Krupnick, Hannah Stevens, Holly Porter-Morgan, Brian Boom, Pedro Acevedo-Rodríguez, James Ackerman, Duane Kolterman, Eugenio Santiago, Christian Torres, Jeanine Velez

Publications and Research

Target 2 of the 2020 Global Strategy for Plant Conservation (GSPC) calls for a comprehensive list of the world's threatened plant species. The lack of such a list is one of the greatest impediments to protecting the full complement of the world's plant species, and work to achieve this has been slow. An efficient system for identifying those species that are at risk of extinction could help to achieve this goal in a time frame sensitive to today's conservation needs. Two systems that efficiently use available data to assess conservation status were tested against a provisional International Union for Conservation …

Label Retention Identifies A Multipotent Mesenchymal Stem Cell-Like Population In The Postnatal Thymus, Masako Osada, Varan J. Singh, Kenmin Wu, Derek B. Sant’Angelo, Mark Pezzano

Publications and Research

Thymic microenvironments are essential for the proper development and selection of T cells critical for a functional and self-tolerant adaptive immune response. While significant turnover occurs, it is unclear whether populations of adult stem cells contribute to the maintenance of postnatal thymic epithelial microenvironments. Here, the slow cycling characteristic of stem cells and their property of label-retention were used to identify a K5-expressing thymic stromal cell population capable of generating clonal cell lines that retain the capacity to differentiate into a number of mesenchymal lineages including adipocytes, chondrocytes and osteoblasts suggesting a mesenchymal stem cell-like phenotype. Using cell surface analysis …

Field Effects And Ictal Synchronization: Insights From In Homine Observations, Shennan A. Weiss, Guy Mckhann Jr., Robert Goodman, Ronald G. Emerson, Andrew Trevelyan, Marom Bikson, Catherine A. Schevon

Publications and Research

It has been well established in animal models that electrical fields generated during inter-ictal and ictal discharges are strong enough in intensity to influence action potential firing threshold and synchronization. We discuss recently published data from microelectrode array recordings of human neocortical seizures and speculate about the possible role of field effects in neuronal synchronization. We have identified two distinct seizure territories that cannot be easily distinguished by traditional EEG analysis. The ictal core exhibits synchronized neuronal burst firing, while the surrounding ictal penumbra exhibits asynchronous and relatively sparse neuronal activity. In the ictal core large amplitude rhythmic ictal discharges …

Transformation Of Stimulus Correlations By The Retina, Kristina D. Simmons, Jason Prentice, Gašper Tkačik, Jan Homann, Heather K. Yee, Stephanie E. Palmer, Philip C. Nelson, Vijay Balasubramanian

Publications and Research

Redundancies and correlations in the responses of sensory neurons may seem to waste neural resources, but they can also carry cues about structured stimuli and may help the brain to correct for response errors. To investigate the effect of stimulus structure on redundancy in retina, we measured simultaneous responses from populations of retinal ganglion cells presented with natural and artificial stimuli that varied greatly in correlation structure; these stimuli and recordings are publicly available online. Responding to spatio-temporally structured stimuli such as natural movies, pairs of ganglion cells were modestly more correlated than in response to white noise checkerboards, but …

Effects Of Water Availability And Pest Pressures On Tea (Camellia Sinensis) Growth And Functional Quality, Selena Ahmed, Colin M. Orians, Timothy S. Griffin, Sarabeth Buckley, Uchenna Unachukwu, Anne Elise Stratton, John Richard Stepp, Albert Robbat Jr, Sean Cash, Edward J. Kennelly

Publications and Research

Extreme shifts in water availability linked to global climate change are impacting crops worldwide. The present study examines the direct and interactive effects of water availability and pest pressures on tea (Camellia sinensis; Theaceae) growth and functional quality. Manipulative greenhouse experiments were used to measure the effects of variable water availability and pest pressures simulated by jasmonic acid (JA) on tea leaf growth and secondary metabolites that determine tea quality. Water treatments were simulated to replicate ideal tea growing conditions and extreme precipitation events in tropical southwestern China, a major centre of tea production. Results show that higher water availability …

An Argument And Plan For Promoting The Teaching And Learning Of Neglected Tropical Diseases, Kevin M. Bonney

Publications and Research

Neglected tropical diseases constitute a significant public health burden, affecting over one billion people globally, yet this group of diseases is underrepresented in the appropriation of both monetary and intellectual capital for developing improved therapies and public health campaigns. The topic of neglected tropical diseases has been similarly marginalized in the biology classrooms of our nation’s high schools and colleges, despite offering an opportunity to teach and learn about a diverse area of microbiology with far-reaching public health, social, and economic implications. Discussed herein is an argument for increasing the representation of neglected tropical diseases in microbiology education as a …

Microfluidic Generated Egf-Gradients Induce Chemokinesis Of Transplantable Retinal Progenitor Cells Via The Jak/Stat And Pi3kinase Signaling Pathways, Uchenna J. Unachukwu, Moira Sauane, Maribel Vazquez, Stephen Redenti

Publications and Research

A growing number of studies are evaluating retinal progenitor cell (RPC) transplantation as an approach to repair retinal degeneration and restore visual function. To advance cell-replacement strategies for a practical retinal therapy, it is important to define the molecular and biochemical mechanisms guiding RPC motility. We have analyzed RPC expression of the epidermal growth factor receptor (EGFR) and evaluated whether exposure to epidermal growth factor (EGF) can coordinate motogenic activity in vitro. Using Boyden chamber analysis as an initial highthroughput screen, we determined that RPC motility was optimally stimulated by EGF concentrations in the range of 20-400ng/ml, with decreased stimulation …