Digital Commons Network^™

Automated Learner Classification Through Interface Event Stream And Summary Statistics Analysis, Edgar E. Troudt

Dissertations, Theses, and Capstone Projects

Reading comprehension is predominately measured through multiple choice examinations. Yet, as we will discuss in this thesis, such exams are often criticized for their inaccuracies. With the advent of "big data" and the rise of ITS (Intelligent Tutoring Systems), increasing focus will be placed on finding dynamic, automated ways of measuring students' aptitude and progress.

This work takes the first step towards automated learner classification based on the application of graphic organizers. We address the following specific problem experimentally: How effectively can we measure task comprehension via human translation of written text into a visual representation on a computer? Can …

Space & Distance As I Require: The Journals And Prose Fragments Of Philip Whalen 1950-1966, Brian Unger

Dissertations, Theses, and Capstone Projects

Space & Distance As I Require: The Journals & Prose Fragments of Philip Whalen 1950 - 1966 presents the early journals, prose fragments, and a few unpublished poems and essays by San Francisco Renaissance and Beat Generation poet Philip Whalen (1923-2002). This work includes a scholarly apparatus with both general literary and textual introductions, a critical bibliography that reflects my literary-historical concerns, brief section introductions, annotations, and an informal concordance with Whalen's poetry utilizing The Collected Poems of Philip Whalen (ed. Rothenberg, 2007) as a reference work.

Philip Whalen was an Irish-American writer with roots in small town Oregon, a …

A Parametrization-Based Surface Reconstruction System For Triangular Mesh Simplification With Application To Large Scale Scenes, Adriana Wise

Dissertations, Theses, and Capstone Projects

The laser scanner is nowadays widely used to capture the geometry of art, animation maquettes, or large architectural, industrial, and land form models. It thus poses specific problems depending on the model scale. This thesis provides a solution for simplification of triangulated data and for surface reconstruction of large data sets, where feature edges provide an obvious segmentation structure. It also explores a new method for model segmentation, with the goal of applying multiresolution techniques to data sets characterized by curvy areas and the lack of clear demarcation features. The preliminary stage of surface segmentation, which takes as input single …

Chemistry Of 6-Monobrominated Indigo, Mbi, Hiroko Ajiki

Dissertations, Theses, and Capstone Projects

6-monobrominated indigo, MBI, is a component of a historically important and the most expensive colorant, Tyrian Purple.

The colorant is remarkably stable under the sun, in the air and after extensive washing with water. The color is still vivid after thousands of years. Even though it has such a high stability, MBI and Tyrian Purple have color changes from purple to blue upon temperature changes. This color change has been known for long to certain people, but the mechanism of the color change was unknown.

Tyrian Purple also has recently attracted interests for applications towards semiconducting material due to its …

The Neurodevelopment Of Basic Sensory Processing And Integration In Autism Spectrum Disorder, Alice Brown Brandwein

Dissertations, Theses, and Capstone Projects

This thesis presents three studies that together explore the neurophysiological basis for the sensory processing and integration abnormalities that have been observed in autism spectrum disorder (ASD) since the disorder was first described over half a century ago. In designing these studies we seek to fill a hole that currently exists in the research community‟s knowledge of the neurodevelopment of basic multisensory integration -- both in children with autism and as well as in those with typical development. The first study applied event related potentials (ERPs) and behavioral measures of multisensory integration to a large group of healthy participants ranging …

Supraspinal And Spinal Mechanisms Of Morphine-Induced Hyperalgesia, Caroline A. Arout

Dissertations, Theses, and Capstone Projects

Morphine is the most prominent pharmacological treatment for moderate to severe pain in both acute and chronic paradigms. However, morphine notoriously elicits a paradoxical state of increased pain sensitivity known as hyperalgesia that complicates its use in clinical application. Research over the past three decades has reported that morphine-induced hyperalgesia is dose- and sex-dependent, and likely involves the synchronous activity of several neural networks beyond the opioid system. Whereas systemic, supraspinal, and spinal administration of morphine all cause hyperalgesia that is differentially reversible by N-methyl-D-aspartate receptor (NMDAR) antagonists or melanocortin-1 receptor (MC1R) antagonists, it is unknown as to whether or …

Candida Albicans Als5p Amyloid In Host-Microbe Interactions: A Ceanorhabditis Elegans Study, Michael Bois

Dissertations, Theses, and Capstone Projects

Candida albicans, a dimorphic fungus and an opportunistic pathogen, possesses a myriad of adherence factors including members of the agglutinin-like sequence (Als) family of mannoproteins. The adhesin Als5p mediates adhesion to many substrates, and is upregulated during commensal interactions, but is downregulated during active C. albicans infections[1]. An amyloid forming core sequence at residues 325-331 has been shown to be important for Als5p function, because a single amino acid substitution at position 326 (V326N) greatly reduces Als5p-mediated adherence[2]. We evaluated the role of Als5p in host-microbe interactions, using Caenorhabditis elegans as a host model and feeding them Saccharomyces cerevisiae expressing …

Property Enhancements Of Dielectric Nanoparticles Via Surface Functionalization, Andrew Byro

Dissertations, Theses, and Capstone Projects

This thesis describes the surface modification of barium strontium titanate nanoparticles for use in polymer/ceramic composite thin film capacitors with resultant improved dielectric and film-making properties. Phosphonic acid-type ligands proved to be most effective for surface conjugation to the surface of the barium strontium titanate nanoparticles. Amine-terminated ligands proved to be effective at removing surface adsorbed water before being almost entirely removed during the sample washing stage. Carboxylic acid terminated ligands proved to adhere less well to the nanoparticle than the phosphonic acid, but resulted in thin films with a higher dielectric constant, which was more stable in the measured …

Non-Standard Italian Dialect Heritage Speakers' Acquisition Of Clitic Placement In Standard Italian, Lionel Chan

Dissertations, Theses, and Capstone Projects

This dissertation examines the acquisition of object clitic placement in Standard Italian by heritage speakers (HSs) of non-standard Italian dialects. It compares two different groups of Standard Italian learners--Northern Italian dialect HSs and Southern Italian dialect HSs--whose heritage dialects contrast with each other in clitic word order. The syntactic constructions tested include restructuring contexts (i.e., constructions in which clitic climbing can take place), and negative first- and second-person informal imperatives. The overarching research question guiding this pilot study is to determine what influences non-standard Italian dialect HSs' clitic placement when learning these constructions in Standard Italian. Three possible sources that …

Acting Wide Awake: Attention And The Ethics Of Emotion, Jacob Davis

Dissertations, Theses, and Capstone Projects

In cases where two human cultures disagree over fundamental ethical values, metaethical questions about what could make one or the other position correct arise with great force. Philosophers committed to naturalistically plausible accounts of ethics have offered little hope of adjudicating such conflicts, leading some to embrace moral relativism. In my dissertation, I develop an empirically grounded response to moral relativism by turning away from debates over which action types are right and wrong and focusing instead on shared features of human emotional motivation. On my account, being motivated by ill-will is ethically bad (if it is), just because human …

I Hope I Don't See You Tomorrow: A Phenomenological Ethnography Of The Passages Academy School Program, Lee Adam Gabay

Dissertations, Theses, and Capstone Projects

This study examines Passages Academy, a school program that offers educational services for court-involved youth in New York City. Looking specifically at the Department of Education teachers who work in facilities run by the Department of Juvenile Justice, this research focuses on the beliefs and behaviors that inform the teaching experience within these facilities. The critical question of how these educators negotiate the learning spaces within this school community is also examined.

The question that informs much of this study is: how are the philosophies of the various stake-holding agencies enacted daily in real classroom settings? This leads to a …

How Important Is Land-Based Foraging To Polar Bears (Ursus Maritimus) During The Ice-Free Season In Western Hudson Bay? An Examination Of Dietary Shifts, Compositional Patterns, Behavioral Observations And Energetic Contributions, Linda J. Gormezano

Dissertations, Theses, and Capstone Projects

Trophic mismatches between predators and their prey are increasing as climate change causes decoupling of phenological relationships. Predators linked to the life histories of a particular prey will have a more difficult time persisting through environmental change unless they can alter their behavior to maintain the historical match or possess the ability to pursue alternate prey. Arctic predators typically possess flexible foraging strategies to survive in the labile environment, however, quantifying the limits of those strategies can be difficult when life history information is incomplete. In such cases, piecing together different aspects of a predator's foraging behavior, particularly when environmental …

An Ethnobotanical, Ecological And Lc-Ms-Based Chemometric Investigation Of Phaleria Nisidai, A Traditional Adaptogen Containing Diterpene Esters From Palau, Micronesia, Daniel Kulakowski

Dissertations, Theses, and Capstone Projects

An ethnobotanical, ecological and LC-MS-based chemometric investigation of Phaleria nisidai, a traditional adaptogen containing diterpene esters from Palau, Micronesia

Palau is a country with a rich heritage of traditional medicine still being practiced. One of the most popular and respected remedies in Palau is a tea made from fresh leaves of Phaleria nisidai Kaneh. (Thymelaeaceae). Interviews conducted to determine the use of this plant revealed that it is employed non-specifically to treat a variety of general health concerns. Its use as a prophylactic to keep away sickness, as a 'system cleaner', as well as for strength and energy indicate …

The Interplay Of Visual Attention And Saccade Planning In Active Vision, Afsheen Khan

Dissertations, Theses, and Capstone Projects

Vision is a highly active process. When we view the world, we do not hold our eyes still, but constantly move them around in order to view the object or area of interest with the fovea (the region of the retina with the highest acuity). Saccades are the step-like movements that we most often employ for this purpose. In addition, our attention is constantly being covertly attracted or directed to points of interest. Combining these different aspects of viewing: visual processing, the orienting of attention, and eye movements can be referred to as `active vision'.

Most work on active vision …

Roundup Ready Nation: The Political Ecology Of Genetically Modified Soy In Argentina, Amalia Leguizamon

Dissertations, Theses, and Capstone Projects

This dissertation is a case study of agrarian transformation in an agro-export society, Argentina. I study the process of adoption of the technological package of genetically modified (GM) soy in the Argentine countryside, its socio-ecological consequences, and Argentines' responses to it. In particular, this research addresses Argentina's unique situation of being a developing country that has positively embraced the biotechnology of GM seeds as a key accumulation strategy without the emergence of major contestation against GM soy monocropping. In order to answer the puzzle of quiescence, I look at how power relations structure access to social and environmental goods and …

Vegf Treatment During Status Epilepticus Alters Long-Term Hippocampal Astrocyte Morphology: A Detailed Description Of Astrocyte Morphology And Glutamate Transporter Patterns With And Without Administration Of Vegf And Seizure Induction, Janice Rene Lenzer

Dissertations, Theses, and Capstone Projects

VEGF treatment during pilocarpine-induced status epilepticus (SE) causes enduring preservation of behavioral function in rats in the absence of enduring neuroprotection (Nicoletti et al., 2010). In addition, VEGF treatment reduces hyperexcitability in hippocampal slices without altering neuronal membrane properties (McCloskey et al, 2005). Combined, these data suggest the possibility that other cells or mechanisms could be involved in the beneficial effects of VEGF during SE. Our laboratory is interested in the potential contribution of astrocytes to these effects. Astrocytes are not only reported to contribute to epileptiform discharges in the hippocampus (Tian et al., 2005; Kang et al., 2005) but …

Occupy Mall Street? How The Court Conditioned Public Space Where People Go, Anthony Maniscalco

Dissertations, Theses, and Capstone Projects

This thesis explores the tension between practicable space and property rights. That tension has frequently animated legal contests over political expression in privately owned, publicly accessible marketplaces in the United States. Do American marketplaces function as marketplaces of ideas? Should they? In order to examine those questions, I survey the Supreme Court's considerations of expressive activity on public and commercial property, in particular, shopping centers. I begin by developing indications of public space, as well as noting the challenges for civic inclusion within the modern political sphere. Next, I survey historical practices of public space within (Western) marketplaces. Those practices …

Nature's Goodness: An Aristotelian Account, Nathan K. Metzger

Dissertations, Theses, and Capstone Projects

Neo-Aristotelians have made major headway in moral theory, and it is now commonplace to find philosophers defending the reality of goodness through a teleological analysis of human being. Whatever the merits of this approach, it has suffered from a lack of a sustained defense of its pre-modern metaphysical panorama: the Aristotelian conception of the human good gets traction only if its decidedly pre-modern and `robust' philosophy of nature is defensible in its own right. In this dissertation, I aim to give a partial breakdown of the particular sort of metaphysical project that the Aristotelian moral theorist assumes, but does not …

Why Should One Reproduce? The Rationality And Morality Of Human Reproduction, Lantz Fleming Miller

Dissertations, Theses, and Capstone Projects

Human reproduction has long been assumed to be an act of the blind force of nature, to which humans were subject, like the weather. However, with recent concerns about the environmental impact of human population, particularly resource depletion, human reproduction has come to be seen as a moral issue. That is, in general, it may be moral or immoral for people to continue propagating their species. The past decade's philosophical discussions of the question have yielded varying results. This dissertation takes on the issue in a broader moral perspective and asks not only whether it is moral to reproduce but …

Intracellular Mechanisms Associated With Cocaine Induced Conditioned Place Preference, Stephanie K. Nygard

Dissertations, Theses, and Capstone Projects

The aim of this dissertation was to investigate the intracellular responses associated with the acquisition and expression of cocaine-context associations. ERK (extracellular regulated kinase), CREB (cAMP responsive element binding protein), FosB and deltaFosB proteins were of particular interest due to their involvement in cocaine reward and in synaptic plasticity underlying learning and memory. We used the conditioned place preference (CPP) paradigm, which employs a Pavlovian conditioning procedure to establish an association between a drug-paired environment and the drug's rewarding effects, to study the role of these signaling pathways in cocaine-context associations. N-methyl-D-aspartate receptor (NMDAR) antagonism prior to cocaine administration during …

On The Role Of Neuronal Oscillations In Auditory Cortical Processing, Monica Noelle O'Connell

Dissertations, Theses, and Capstone Projects

Although it has been over 100 years since William James stated that "everyone knows what attention is", its underlying neural mechanisms are still being debated today. The goal of this research was to describe the physiological mechanisms of auditory attention using direct electrophysiological recordings in macaque primary auditory cortex (A1). A major focus of my research was on the role ongoing neuronal oscillations play in attentional modulation of auditory responses in A1.

For all studies, laminar profiles of synaptic activity, (indexed by current source density analysis) and concomitant firing patterns in local neurons (multiunit activity) were acquired simultaneously via linear …

Comparative Modeling And Functional Characterization Of Two Enzymes Of The Cyclooxygenase Pathway In Drosophila Melanogaster, Yan Qi

Dissertations, Theses, and Capstone Projects

Eicosanoids are biologically active molecules oxygenated from twenty carbon polyunsaturated fatty acids. Natural eicosanoids exert potent biological effects in humans, and a great deal of pharmaceutical research has led to the discovery of compounds for selective inhibition of specific enzymes in eicosanoid biosynthesis. Coupled with different receptors, eicosanoids mediate various physiological and pathophysiological processes, including fever generation, pain response, vasoconstriction, vasodilation, platelet aggregation, platelet declumping, body temperature maintenance and sleep-wake cycle regulation. In mammals, the eicosanoid biosynthesis has three pathways: the cyclooxygenase (COX) pathway, the lipoxygenase (LOX) pathway and the epoxygenase pathway. The COX pathway synthesizes prostanoids, which are important …

Neuroimmune Crosstalk: A Role For Neuropeptide Y In Inflammatory Bowel Disease, Henry H. Ruiz

Dissertations, Theses, and Capstone Projects

Neuropeptide Y (NPY) is a 36-amino acid peptide widely expressed in the central and peripheral nervous systems. In addition to other cells, NPY is also synthesized and co-released from sympathetic nerve fibers functioning as a potent sympathetic neuromodulator. NPY has been implicated in playing important roles in the regulation of energy balance, appetite, anxiety, vascular tone, and immune cell functioning. In addition, immune cells of both the innate and adaptive immune systems express functional NPY receptors. Some immune cells can produce and secrete NPY, and genetic alteration of these receptors results in altered immune cell functioning. Its direct association with …

Common Knowledge: The Epistemology Of American Realism, Mark Sussman

Dissertations, Theses, and Capstone Projects

My dissertation, Common Knowledge: The Epistemology of American Realism, focuses on realist fiction (primarily the novel) at the end of the nineteenth century. Its motivating claim is that the central descriptive and thematic imperative of realism--to depict life "as it is" rather than in some idealized form--emerged in response to crises in the status of knowledge that resulted from an attempt by writers and readers to come to a common understanding of the relationship between private experience and an increasingly fragmented social world. While William Dean Howells's definition of realism as a form of writing that displays "fidelity to experience …

The Effect Of Malintent On Visual Attention, David Brian Wallace

Dissertations, Theses, and Capstone Projects

Malintent is a relatively unexplored phenomenon, despite the practical and theoretical interest in its detection. The four studies presented here, informed by the Guilty Knowledge Test and Guided Search model of visual attention, illustrate how eye tracking can (and cannot) be utilized to detect malicious intent. Malintent, induced in two different mock crime paradigms (murder; theft), boosted the frequency and duration of fixations that fell upon objects relevant to their task. The size of the malintent effect ranged from moderate (fixation duration) to large (fixation frequency). The increased visual attention given to task-relevant objects was not unique to malintent; benign …

Clue, Code, Conjure: The Epistemology Of American Detective Fiction, 1841-1914, Jennifer Weiss

Dissertations, Theses, and Capstone Projects

This dissertation posits American detective fiction between 1841 and 1914 as a meaningful category and interrogates forms of knowledge used in this genre. The conventional wisdom on detective fiction creates a dichotomy of British and American production, with British detective fiction in a rational style dominating in importance into the 1920s, and American detective fiction dominating in importance with the "hard-boiled" style of the 1930s and '40s (as described by Raymond Chandler). This dissertation argues that American detective fiction is a meaningful category before and beyond the hard-boiled style.

Abductive reasoning, a form of logic based on observation, hypothesis, and …

Mechanisms Of Deadenylation Regulation Under Different Cellular Conditions, Xiaokan Zhang

Dissertations, Theses, and Capstone Projects

Control of gene expression by regulating mRNA stability after DNA damage has the potential to contribute to the cells rapid response to stress. The main focus of this dissertation is to elucidate the role(s) of nuclear PARN deadenylase in controlling mRNA stability, hence gene expression, of factors in the p53 signaling pathway during the DNA damage response (DDR). Understanding the mechanisms of these regulatory pathways will provide new insights on how the control of gene expression upon DNA damage decides cellular fate, offering new opportunities for therapeutics. In Chapter II, I presented evidence that PARN along with the cleavage factor …

The Interchange Of Plain Velar And Aspirate In Kronos/Chronos: A Case For Etymological Equivalence, Roberto Peter Bongiovanni

Dissertations, Theses, and Capstone Projects

Despite the current state of uncertainty regarding the etymology of Kronos, the equivalence long familiar to the ancients between Kronos and Chronos is still a moot point. Arguments denying their etymological equivalence can no longer firmly rely on linguistic arguments. It is therefore necessary to examine the validity of the time-honored interpretation of Kronos as the personification of Time. The solution to this problem is of considerable importance to Classical studies, since it will not so much as contribute to a better understanding of the myth of Kronos, as the interpretation of Kronos as Time is already familiar from ancient …

Physiological Correlates Of Emotion Regulation In Depersonalization Disorder, Kai-Mosadi Monde

Dissertations, Theses, and Capstone Projects

Depersonalization disorder (DPD), is an often debilitating DSM V psychiatric disorder characterized by feelings of detachment from the self or others as well as emotional blunting or numbness. Subjective and physiological evidence of decreased emotional arousal may suggest impaired emotion regulation abilities. Deficits in emotional processing of DPD may be the result of dysregulated cortisol and oxytocin levels, however oxytocin levels have never been assessed in DPD. In this series of studies, we aimed to investigate the physiological correlates of emotion regulation in depersonalization disorder. In experiment 1, DPD patients and a normal control group subjectively enhanced and suppressed emotion …

Transformative Science Education Through Action Research And Self-Study Practices, Olga Calderon

Dissertations, Theses, and Capstone Projects

The research studies human emotions through diverse methods and theoretical lenses. My intention in using this approach is to provide alternative ways of perceiving and interpreting emotions being experienced in the moment of arousal. Emotions are fundamental in human interactions because they are essential in the development of effective relationships of any kind and they can also mediate hostility towards others. I begin by presenting an impressionist auto-ethnography, which narrates a personal account of how science and scientific inquiry has been entrenched in me since childhood. I describe how emotions are an important part of how I perceive and respond …