Digital Commons Network^™

Assault On Peer Review A New Threat, Aldemaro Romero Jr.

Publications and Research

On October 17, Sen. Rand Paul (R-KY) introduced to the Senate U.S. Committee of Homeland Security and Governmental Affairs a bill titled “BASIC Research Act.” This apparent innocent title covers the real intention of this legislation – an attempt to defund basic research and make it subject to partisan politics. This legislation would change the way grant proposals are evaluated by all federal agencies, from the National Science Foundation (NSF) and the National Institutes of Health (NIH) to the National Endowment for the Humanities (NEH). These and other federal agencies are the main funders of scholarly work in higher education …

Connectivity Motifs Of Inhibitory Neurons In The Mouse Auditory Cortex, Hysell V. Oviedo

Publications and Research

Connectivity determines the function of neural circuits and it is the gateway to behavioral output. The emergent properties of the Auditory Cortex (ACx) have been difficult to unravel partly due to our assumption that it is organized similarly to other sensory areas. But detailed investigations of its functional connectivity have begun to reveal significant differences from other cortical areas that perform different functions. Using Laser Scanning Photostimulation we previously discovered unique circuit features in the ACx. Specifically, we found that the functional asymmetry of the ACx (tonotopy and isofrequency axes) is reflected in the local circuitry of excitatory inputs to …

The Ticker, December 4, 2017

The Ticker

The Ticker is the student newspaper of Baruch College. It has been published continuously since 1932, when the Baruch College campus was the School of Business and Civic Administration of the City College of New York.

Pretargeting Of Internalizing Trastuzumab And Cetuximab With A 18f-Tetrazine Tracer In Xenograft Models, Outi Keinänen, Kimberly Fung, Jacob Pourat, Vilma Jallinoja, Delphine Vivier, Nagavara Kishore Pillarsetty, Anu J. Airaksinen, Jason S. Lewis, Brian M. Zeglis, Mirkka Sarparanta

Publications and Research

Background: Pretargeting-based approaches are being investigated for radioimmunoimaging and therapy applications to reduce the effective radiation burden to the patient. To date, only a few studies have used short-lived radioisotopes for pretargeting of antibodies, and such examples with internalizing antibodies are even rarer. Herein, we have investigated pretargeting methodology using inverse electron-demand Diels-Alder (IEDDA) for tracing two clinically relevant, internalizing monoclonal antibodies, cetuximab and trastuzumab.

Results: Bioorthogonal reaction between tetrazine and trans-cyclooctene (TCO) was used for tracing cetuximab and trastuzumab in vivo with a fluorine-18 (t½ = 109.8 min) labelled tracer. TCO-cetuximab or TCO-trastuzumab was administered 24, 48, or 72 …

The Problem Of Illusion In The Phenomenology Of Claude Romano, Joseph Cutolo

Student Theses and Dissertations

The phenomenology of Claude Romano constructs a strict distinction between perceptions and illusions. This distinction is so strict that the former excludes the latter completely. Putting this distinction into play is not a local decision about our experiences and the structures of our experiences. This decision brings with it metaphysical, ontological, and phenomenological frameworks to ground it. In what follows I attempt to draw out the consequences of Romano’s decisions about our experience, and to study the philosophical frameworks that underlie his decisions. In doing so, I reconnect his phenomenology with a wider terminology of phenomenology, in order to study …

Study Of Self-Similarity In Brain Data, Jennifer Holst

Student Theses

In the area of computer science, past research has found that the concept of self-similarity is present in local and Internet-based network traffic. This study considers the possibility that data traveling through the neuronal network in the human brain is also self-similar. By analyzing publicly available raw EEG data and estimating its Hurst parameter, we find indications that brain data traffic may in fact be self-similar.

Relative Contribution Of Neutral And Deterministic Processes In Shaping Fruit-Feeding Butterfly Assemblages In Afrotropical Forests, Kwaku Aduse-Poku, Freerk Molleman, William Oduro, Samuel K. Oppong, David J. Lohman, Rampal S. Etienne

Publications and Research

The unified neutral theory of biodiversity and biogeography has gained the status of a quantitative null model for explaining patterns in ecological (meta)communities. The theory assumes that individuals of trophically similar species are functionally equivalent. We empirically evaluate the relative contribution of neutral and deterministic processes in shaping fruit-feeding butterfly assemblages in three tropical forests in Africa, using both direct (confronting the neutral model with species abundance data) and indirect approaches (testing the predictions of neutral theory using data other than species abundance distributions). Abundance data were obtained by sampling butterflies using banana baited traps set at the forest canopy …

Caenorhabditis Elegans Dbl-1/Bmp Regulates Lipid Accumulation Via Interaction With Insulin Signaling, James F. Clark, Michael Meade, Gehan Ranepura, David H. Hall, Cathy Savage-Dunn

Publications and Research

Metabolic homeostasis is coordinately controlled by diverse inputs. Understanding these regulatory networks is vital to combating metabolic disorders. The nematode Caenorhabditis elegans has emerged as a powerful, genetically tractable model system for the discovery of lipid regulatory mechanisms. Here we introduce DBL-1, the C. elegans homolog of bone morphogenetic protein 2/4 (BMP2/4), as a significant regulator of lipid homeostasis. We used neutral lipid staining and a lipid droplet marker to demonstrate that both increases and decreases in DBL-1/BMP signaling result in reduced lipid stores and lipid droplet count. We find that lipid droplet size, however, correlates positively with the level …

Efficient Air Desulfurization Catalysts Derived From Pig Manure Liquefaction Char, Rajiv Wallace, Sundaramurthy Suresh, Elham H. Fini, Teresa Bandosz

Publications and Research

Biochar from the liquefaction of pig manure was used as a precursor of H2S desulfurization adsorbents. In its inorganic matter, it contains marked quantities of calcium, magnesium and iron, which are known as hydrogen sulfide oxidation catalysts. The char was used either as-received or mixed with 10% nanographite. The latter was added to increase both the content of the carbon phase and conductivity. ZnCl2 in two different ratios of char to an activation agent (1:1 and 1:2) was used to create the porosity in the carbon phase. The content of the later was between 18–45%. The activated samples adsorbed 144 …

Borrego Studies African Wildlife And Its Future, Aldemaro Romero Jr.

Publications and Research

“Biology blends the best of both worlds for me. My father was a veterinarian, so I grew up with animals and rehabilitating wildlife. My mother was a flight attendant, so she traveled a lot. Biology gave me this wonderful opportunity to study science and ask questions about how nature works, but also to travel to these wonderful foreign locations like Africa, where I’ve done my work on the behavior of lions.”

That is how Dr. Natalia Borrego explains how she got into biology. A native of Lubbock, Texas, she went on to obtain a bachelor’s in wildlife ecology and conservation …

Ethical Veganism, Virtue, And Greatness Of The Soul, Carlo Alvaro

Publications and Research

Many moral philosophers have criticized intensive animal farming because it can be harmful to the environment, it causes pain and misery to a large number of animals, and furthermore eating meat and animal-based products can be unhealthful. The issue of industrially farmed animals has become one of the most pressing ethical questions of our time. On the one hand, utilitarians have argued that we should become vegetarians or vegans because the practices of raising animals for food are immoral since they minimize the overall happiness. Deontologists, on the other hand, have argued that the practices of raising animals for food …

Mode Of Delivery And Child And Adolescent Psychological Well-Being: Evidence From Hong Kong’S “Children Of 1997” Birth Cohort, Cherry Y. Leung, Gabriel M. Leung, C. Mary Schooling

Publications and Research

Mode of delivery (vaginal or cesarean section) is thought to affect gut microbiota, which in turn may affect psychological well-being. As such, mode of delivery is potentially a modifiable factor for psychological well-being. Here we examined the association of mode of delivery with child and adolescent psychological well-being. We used multivariable linear regression in a populationrepresentative Hong Kong Chinese birth cohort, “Children of 1997,” to examine the adjusted associations of mode of delivery with behavioral problems assessed from parent-reported Rutter score at ~7 (n = 6294) and ~11 years (n = 5598), self-esteem assessed from self-reported Culture-Free Self- Esteem Inventory …

Interventions For Young Bereaved Children: A Systematic Review And Implications For School Mental Health Providers, Cliff (Yung-Chi) Chen

Publications and Research

Background: Many young children experience the death of a family member and they may be at risk for developing psychological and behavioral problems, but not much is known about how to help young children cope with such a stressful and painful experience. Objective: The purposes of this study are to identify the interventions for bereaved young children and examine the effectiveness of the interventions. Method: A systematic review of the literature was performed to investigate the effects of interventions for preschool-age children (3-5 years) who experience the death of a family member. Results: Seventeen studies that met the inclusion criteria …

Nlrp10 Enhances Cd4+ T-Cell-Mediated Ifnγ Response Via Regulation Of Dendritic Cell-Derived Il-12 Release, Maurizio Vacca, Julia Böhme, Lisa Zambetti, Hanif Javanmard Khameneh, Bhairav S. Paleja, Federica Laudisi, Adrian W. S. Ho, Kurt Neo, Keith Weng Kit Leong, Mardiana Marzuki, Bernett Lee, Michael Poidinger, Laura Santambrogio, Liana Tsenova, Francesca Zolezzi, Gennaro De Libero, Amit Singhal, Alessandra Mortellaro

Publications and Research

NLRP10 is a nucleotide-binding oligomerization domain-like receptor that functions as an intracellular pattern recognition receptor for microbial products. Here, we generated a Nlrp10−/− mouse to delineate the role of NLRP10 in the host immune response and found that Nlrp10−/− dendritic cells (DCs) elicited sub-optimal IFNγ production by antigenspecific CD4+ T cells compared to wild-type (WT) DCs. In response to T-cell encounter, CD40 ligation or Toll-like receptor 9 stimulation, Nlrp10−/− DCs produced low levels of IL-12, due to a substantial decrease in NF-κB activation. Defective IL-12 production was also evident in vivo and affected IFNγ production by CD4+ T cells. Upon …

A Refuge For Jae-In Doe: Fugues In The Key Of English Major, Seo-Young J. Chu

Publications and Research

"A Refuge for Jae-in Doe: Fugues in the Key of English Major"

Author(s):

Seo-Young Chu (see profile)

Date:

2017

Subject(s):

Feminism, Creative nonfiction, Asian American literature, Sonnets, Social justice, Trauma

Item Type:

Essay

Tag(s):

#MeToo, Stanford, women in academia, early american

Permanent URL:

http://dx.doi.org/10.17613/cp82-8f39

Can Avicenna Help Manage The Diabetes Epidemic In Central Asia?, Mizhgona Sharofova, Yusuf Nuraliev, Parviz Sukhrobov, Shoista Sagdieva, Vyacheslav Dushenkov

Publications and Research

Objectives: The fast-rising rate of diabetes incidents is a growing concern in Central Asian countries. This article reviews the current understanding of type 2 diabetes etiology, progression and treatment options along with opportunities for utilizing Avicenna’s legacy in developing novel botanical therapeutics. Methods: Analysis of relevant publications, including a variety of Avicenna’s work in Arabic, English and Russian. Results: With conventional treatment strategy shifting from single-component drugs aimed at one target to multitherapeutic combinations addressing the complex nature of many diseases and conditions, the role of multicomponent botanical preparations may increase. Diabetes mellitus is a serious chronic, progressive disease characterized …

Songbirds Work Around Computational Complexity By Learning Song Vocabulary Independently Of Sequence, Dina Lipkind, Anja T. Zai, Alexander Hanuschkin, Gary F. Marcus, Ofer Tchernichovski, Richard H.R. Hahnloser

Publications and Research

While acquiring motor skills, animals transform their plastic motor sequences to match desired targets. However, because both the structure and temporal position of individual gestures are adjustable, the number of possible motor transformations increases exponentially with sequence length. Identifying the optimal transformation towards a given target is therefore a computationally intractable problem. Here we show an evolutionary workaround for reducing the computational complexity of song learning in zebra finches. We prompt juveniles to modify syllable phonology and sequence in a learned song to match a newly introduced target song. Surprisingly, juveniles match each syllable to the most spectrally similar sound …

From Local To Global: The Role Of Interdisciplinary Place-Based Research In Teaching Environmental Economics, Sean P. Macdonald

Publications and Research

This chapter examines the value of student engagement in interdisciplinary place-based research - where the exploration of “place” assumes a central component of students’ semester research projects in an undergraduate Environmental Economics class. It considers the benefits of teaching from an interdisciplinary perspective while employing the resources of the local community as a laboratory where students engage in research linked to place - the local community, urban space or a virtual location - encouraging students to make meaningful connections between the theoretical study of local and global environmental problems and the actual observation and investigation of those challenges in real …

Psychological Research In Action: Mentoring At An Urban Hsi Institution With Intersectional Perspectives And Outcomes, Pa Her, Jean E. Hillstrom, Amanda Almond

Publications and Research

This paper is from the perspective of three women who are psychology faculty members at various points in their professional development. It was written with the intention to promote ways for students and faculty members of color to construct representations of themselves as mentors. The New York City College of Technology’s (City Tech) participation in National Science Foundation (NSF) and National Institute of Health (NIH) grants, as well as institutionally-funded research initiatives, provided the authors with a context for engaging undergraduate students through research within the field of psychology. City Tech is a Hispanic serving institution with an urban campus …

Cryptic Diversity And Discordance In Single‐Locus Species Delimitation Methods Within Horned Lizards (Phrynosomatidae: Phrynosoma), Christopher Blair, Robert W. Bryson Jr.

Publications and Research

Biodiversity reduction and loss continues to progress at an alarming rate, and thus there is widespread interest in utilizing rapid and efficient methods for quantifying and delimiting taxonomic diversity. Single-locus species-delimitation methods have become popular, in part due to the adoption of the DNA barcoding paradigm. These techniques can be broadly classified into tree-based and distance-based methods depending on whether species are delimited based on a constructed genealogy. Although the relative performance of these methods has been tested repeatedly with simulations, additional studies are needed to assess congruence with empirical data. We compiled a large data set of mitochondrial ND4 …

The Ticker, October 30, 2017

The Ticker

The Ticker is the student newspaper of Baruch College. It has been published continuously since 1932, when the Baruch College campus was the School of Business and Civic Administration of the City College of New York.

Development And Validation Of The Microbiology For Health Sciences Concept Inventory, Heather M. Seitz, Rachel E. A. Horak, Megan W. Howard, Lucy W. Kluckhohn Jones, Theodore Muth, Christopher Parker, Andrea Pratt Rediske, Maureen M. Whitehurst

Publications and Research

Identifying misconceptions in student learning is a valuable practice for evaluating student learning gains and directing educational interventions. By accurately identifying students’ knowledge and misconceptions about microbiology concepts, instructors can design effective classroom practices centered on student understanding. Following the development of ASM’s Curriculum Guidelines in 2012, we developed a concept inventory, the Microbiology for Health Sciences Concept Inventory (MHSCI), that measures learning gains and identifies student misconceptions in health sciences microbiology classrooms. The 23-question MHSCI was delivered to a wide variety of students at multiple institution types. Psychometric analysis identified that the MHSCI instrument is both discriminatory and reliable …

Ecosystem Drought Response Timescales From Thermal Emission Versus Shortwave Remote Sensing, Erika Andujar, Nir Krakauer, Chuixiang Yi, Felix Kogan

Publications and Research

Remote sensing is used for monitoring the impacts of meteorological drought on ecosystems, but few large-scale comparisons of the response timescale to drought of different vegetation remote sensing products are available. We correlated vegetation health products derived frompolar-orbiting radiometer observations with a meteorological drought indicator available at different aggregation timescales, the Standardized Precipitation Evapotranspiration Index (SPEI), to evaluate responses averaged globally and over latitude and biome.The remote sensing products are Vegetation Condition Index (VCI), which uses normalized difference vegetation index (NDVI) to identify plant stress, Temperature Condition Index (TCI), based on thermal emission as a measure of surface temperature, and …

Tribalism Is Consuming The World, Aldemaro Romero Jr.

Publications and Research

There is a ghost wandering countries, societies, and even the halls of academia. It is the ghost of tribalism and that ghost is as old as the dawn of the human species.

One of the defining characteristics of people around the world, is to group ourselves for our own ben- efit. Since before any civilization could be described as such, we bound together to defend ourselves from other humans, for cooperating to seek food, to build our shelters, and many more things. That is why we fought wars, conquered territories, subjugate others, and developed characteristics that define ourselves based on …

The Ticker, October 16, 2017

The Ticker

The Ticker is the student newspaper of Baruch College. It has been published continuously since 1932, when the Baruch College campus was the School of Business and Civic Administration of the City College of New York.

Veganism As A Virtue: How Compassion And Fairness Show Us What Is Virtuous About Veganism, Carlo Alvaro

Publications and Research

With millions of animals brought into existence and raised for food every year, their negative impact upon the environment and the staggering growth in the number of chronic diseases caused by meat and dairy diets make a global move toward ethical veganism imperative. Typically, utilitarians and deontologists have led this discussion. The purpose of this paper is to pro- pose a virtuous approach to ethical veganism. Virtue ethics can be used to construct a defense of ethical veganism by relying on the virtues of compassion and fairness. Exercising these values in our relations with animals involves acknowledging their moral value, …

Spinal Excitability Changes After Transspinal And Transcortical Paired Associative Stimulation In Humans, Maria Knikou

Publications and Research

Paired associative stimulation (PAS) produces enduring neuroplasticity based on Hebbian associative plasticity. This study established the changes in spinal motoneuronal excitability by pairing transcortical and transspinal stimulation. Transcortical stimulation was delivered after (transspinal-transcortical PAS) or before (transcortical-transspinal PAS) transspinal stimulation. Before and after 40 minutes of each PAS protocol, spinal neural excitability was assessed based on the amplitude of the transspinal-evoked potentials (TEPs) recorded from ankle muscles of both legs at different stimulation intensities (recruitment input-output curve). Changes in TEPs amplitude in response to low-frequency stimulation and paired transspinal stimuli were also established before and after each PAS protocol. TEP …

Effects Of A Beach Nourishment Project In Jamaica Bay, New York, On Horseshoe Crab (Limulus Polyphemus) Spawning Activity And Egg Deposition, Christina P. Colon

Publications and Research

Restoration of horseshoe crab spawning habitats through beach nourishment may be considered as a potential strategy to enhance reproductive success in areas where estuarine beaches have been lost to coastal erosion and development. The US Army Corps of Engineers performed a beach nourishment project at Plumb Beach (Jamaica Bay, Brooklyn, NY) in 2012 to stabilize the shoreline. While the addition of sand was done to protect infrastructure, it created an opportunity to examine the responses of American horseshoe crabs (Limulus polyphemus) to beach nourishment using a BACI (before-after control impact) design. During Spring 2012, be fore beach nourishment, horseshoe crabs …

The Impact Of Climate Change On Biodiversity In Nepal: Current Knowledge, Lacunae, And Opportunities, Aishwarya Bhattacharjee, Jose D. Anadon, David L. Lohnman, Tenzing Doleck, Tarendra Lakhankar, Bharat Babu Shrestha, Praseed Thapa, Durga Devkota, Sundar Tiwari, Ajay Jha, Mohan Siwakoti, Naba R. Devkota, Pramod K. Jha, Nir Y. Krakauer

Publications and Research

Nepal has an extreme altitudinal range from 60–8850m with heterogeneous topography and distinct climatic zones. The country is considered a biodiversity hotspot, with nearly a quarter of the land area located in protected areas. Nepal and the surrounding Himalayan region are particularly vulnerable to climate change because of their abrupt ecological and climatic transitions. Tens of millions of people rely on the region’s ecosystem services, and observed and modeled warming trends predict increased climate extremes in the Himalayas. To study the ecological impacts of climate change in Nepal and inform adaptation planning, we review the literature on past, present, and …

Escape Burrowing Of Modern Freshwater Bivalves As A Paradigm For Escape Behavior In The Devonian Bivalve Archanodon Catskillensis, Katja Knoll, Rebecca B. Chamberlain, John A. Chamberlain

Publications and Research

Many freshwater bivalves restore themselves to the sediment water interface after burial by upward escape burrowing. We studied the escape burrowing capacity of two modern unionoids, Elliptio complanata and Pyganodon cataracta and the invasive freshwater venerid Corbicula fluminea, in a controlled laboratory setting varying sediment grain size and burial depth. We found that the relatively streamlined E. complanata is a better escape burrower than the more obese P. cataracta. E. complanata is more likely to escape burial in both fine and coarse sand, and at faster rates than P. cataracta. However, successful escape from 10 cm burial, especially in fine …