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Retinal Precursor Cell Enriched Multiomic And Pseudo-Time Analysis Of Developing And Reprogrammed Photoreceptors, Brendon M. Patierno Sep 2025

Retinal Precursor Cell Enriched Multiomic And Pseudo-Time Analysis Of Developing And Reprogrammed Photoreceptors, Brendon M. Patierno

Dissertations, Theses, and Capstone Projects

The vertebrate retina is a complex tissue made up of seven major cell subtypes which during development must differentiate and localize into a highly organized structure. These neuronal cells do not regenerate if damaged or diseased, and the progressive deterioration of cone photoreceptor cells is the leading cause of age related blindness. Currently there are no cures for this disease, but one promising therapeutic avenue is cell transplantation research. If we can further elucidate the gene regulatory networks that define cone cell development, this knowledge could be applied to the generation of healthy cone cells in clinically relevant models.

The …


Exploring The Role Of Ecological Traits In Shaping Spatial Patterns Of Genetic Diversity, Rilquer Mascarenhas Da Silva Sep 2025

Exploring The Role Of Ecological Traits In Shaping Spatial Patterns Of Genetic Diversity, Rilquer Mascarenhas Da Silva

Dissertations, Theses, and Capstone Projects

The field of comparative phylogeography aims at uncovering common underlying causes for shared patterns of diversity and diversification at the population level. However, it is now widely accepted that intraspecific genetic diversity patterns can differ considerably across co-occurring taxa due to ecological processes acting at the population level (and influencing individual movement and abundance). To model the processes underlying lineage diversification and demographic shifts in response to environmental changes, phylogeographers and population geneticists are now faced with the challenge of incorporating measurements of species ecological traits into their molecular studies. This dissertation aimed at investigating how different types of ecological …


Repurposing Atractylenolide Iii, A Natural Anti-Inflammatory Compound, For Alzheimer’S Disease, Angela M. Steele Sep 2025

Repurposing Atractylenolide Iii, A Natural Anti-Inflammatory Compound, For Alzheimer’S Disease, Angela M. Steele

Dissertations, Theses, and Capstone Projects

Alzheimer’s disease (AD) is a debilitating neurological condition ranked as the fifth leading cause of death in adults over the age of 65. Despite the severity, 98% of drugs have failed as treatments for AD. Current novel drug development approaches have been unable to produce a disease-modifying treatment as they often have a one-target approach, not accounting for the complex nature of the disease. One of the hallmarks of the disease, inflammation, may provide a better target for treatment because it interacts with multiple facets of the disease. Drug repurposing to identify compounds that mitigate inflammation in AD could provide …


Reduce, Replace, Reframe: How Civil Society Organizations Build Resilience In The Face Of Financial And Political Pressures, Merrill Sovner Sep 2025

Reduce, Replace, Reframe: How Civil Society Organizations Build Resilience In The Face Of Financial And Political Pressures, Merrill Sovner

Dissertations, Theses, and Capstone Projects

In order for civil society organizations (CSOs) to perform essential functions to support democracy and prevent democratic erosion, they must operate sustainably, maintaining resources and legitimacy to carry out their missions. CSOs experience financial and political pressures when resources and legitimacy are withdrawn. CSOs facing both pressures may reduce their activities, replace lost funding, or reframe their work to engage new audiences. How CSOs respond in the face of financial and political pressures has implications for their role in hindering democratic erosion. Yet civil society organizations weather these pressures in ways that are not straightforward; the most targeted organizations may …


Scripted For Surveillance: Parole Revocation Hearings And The Performance Of Procedure In New York, Kelsey G. Greeff Sep 2025

Scripted For Surveillance: Parole Revocation Hearings And The Performance Of Procedure In New York, Kelsey G. Greeff

Dissertations, Theses, and Capstone Projects

This thesis examines parole revocation hearings in New York as complex performances that extend carceral control beyond prison walls. Drawing on a composite vignette from the Bronx parole court, it analyzes the interplay between procedural reform, constitutional due process, and neoliberal governance. Using a dramaturgical framework informed by Michel Foucault’s discourse analysis and Judith Butler’s theory of performativity, the study identifies four interrelated processes: the judge as director, who orchestrates hearings according to institutional priorities; normalization, where repetition embeds structural inequality as routine; type-marking, the classification of parolees into predefined roles through accumulated records and cues; and the extension of …


Isolation And Divergence Of Greater Earless Lizards (Phrynosomatidae: Cophosaurus) In Western North America Support Multiple Diversification Processes And A Complex Demographic History, Christopher Robert Blair, Carlos Joaquín Pavón-Vázquez, Qaantah Rana, Keaka Farleigh, Erika Crispo, Thomas Panzera, Felipe De Medeiros Magalhães, Britt White, Uri Omar Garcia-Vazquez Aug 2025

Isolation And Divergence Of Greater Earless Lizards (Phrynosomatidae: Cophosaurus) In Western North America Support Multiple Diversification Processes And A Complex Demographic History, Christopher Robert Blair, Carlos Joaquín Pavón-Vázquez, Qaantah Rana, Keaka Farleigh, Erika Crispo, Thomas Panzera, Felipe De Medeiros Magalhães, Britt White, Uri Omar Garcia-Vazquez

Publications and Research

The Southwestern US and northern Mexico continue to serve as ideal regions to elucidate the suite of ecological and evolutionary processes influencing lineage diversification. The complex geological history of arid North America, coupled with paleoclimate change during the Pleistocene and diverse ecoregions makes a multipronged approach to hypothesis testing necessary. We combine thousands of loci from a genotyping-by-sequencing (GBS) approach along with mitochondrial DNA (mtDNA) sequences from the Greater Earless Lizard (Cophosaurus texanus) to examine diversity and test for cryptic population structure. We also apply recently developed coalescent approaches in a Bayesian framework to estimate migration rates. Population …


Inhibitory Control In Asian Elephants, Gillian Schmitt Aug 2025

Inhibitory Control In Asian Elephants, Gillian Schmitt

Theses and Dissertations

Inhibitory control is defined as the ability to suppress a prepotent motor response in favor of a more efficient or advantageous behavior, and is an important core executive function. Although elephants are known to behave flexibly and display other executive functions, there is currently little information available on if, and to what extent, they display inhibitory control. We tested 16 captive Asian elephants (Elephas maximus) (N = 8 males, 8 females) ranging in age from 4-years-old to 60-years-old at the National Elephant Institute in Thailand using a classic detour paradigm adapted to be more ecologically salient for them through the …


The Automation Of Aesthetics: Artificial Intelligence And Commercial Artists In North Brooklyn, Devin Sudweeks Aug 2025

The Automation Of Aesthetics: Artificial Intelligence And Commercial Artists In North Brooklyn, Devin Sudweeks

Theses and Dissertations

Corporate elites expect generative AI to replace commercial artists but overlook their social and aesthetic expertise. This ethnographic study explores how Brooklyn-based commercial artists narrate their value amid automation, emphasizing embodied presence in cultural scenes, visual language, style, and authenticity, skills not easily mechanized but vital to aesthetic economies.


Learning From Adolescents’ Lived Experience: Recommendations For Suicide Prevention For Youth And Their Caregivers, Genesis Minaya Aug 2025

Learning From Adolescents’ Lived Experience: Recommendations For Suicide Prevention For Youth And Their Caregivers, Genesis Minaya

Theses and Dissertations

This study explored adolescents’ views on which supports are most helpful during suicidal thoughts or behaviors. Interviews revealed six themes: Communication & Disclosure, Empathic Non-Judgmental Support, Consistent Presence, Parent/Family Education, Coping Tools, Hope and Future Orientation. These findings highlight the critical role of family dynamics in adolescent suicide prevention.


In The Name Of The Mother, The Nation, And The Race: White Women, The Jim Crow South, & Moralized White Supremacist Feminism, Shayna M. Lawson Aug 2025

In The Name Of The Mother, The Nation, And The Race: White Women, The Jim Crow South, & Moralized White Supremacist Feminism, Shayna M. Lawson

Theses and Dissertations

This thesis introduces the concept of moralized white supremacist feminism to examine the central role white women played in constructing, legitimizing, and sustaining racial hierarchies in the Jim Crow South through a network of cultural and political organizing, particularly through the United Daughters of the Confederacy and Women’s Ku Klux Klan. Far from passive observers, white women were strategic agents of segregation, leveraging ideals of purity, motherhood, and moral virtue to enforce anti-Black violence and oppression through educational, civic, legal, and symbolic institutions, as well as extra-legal practices. Drawing from archival materials, oral histories, and critical race theory, this study …


Reverse-Chinoiserie: Qing Imperial Porcelain And The Reappropriation Of European Rococo, Yifan (Mia) Ye Aug 2025

Reverse-Chinoiserie: Qing Imperial Porcelain And The Reappropriation Of European Rococo, Yifan (Mia) Ye

Theses and Dissertations

This thesis introduces “reverse-chinoiserie” to describe the Qing court’s reappropriation of European Rococo aesthetics in imperial porcelain. Through case studies of 18th-century ceramic diplomacy and design, it reveals how cultural imitation was reengineered into visual sovereignty. It examines how China responded to, absorbed, and redirected European fantasies of empire.


Cartography, Botany, And Violence In The Codex Rodriguez-MondragóN, Maria Davison Aug 2025

Cartography, Botany, And Violence In The Codex Rodriguez-MondragóN, Maria Davison

Theses and Dissertations

This thesis examines how Sandy Rodriguez deploys the visual language of the Florentine Codex and other sixteenth-century Mesoamerican sources to examine the persisting effects of colonialism on people and land in Mexico-U.S. borderlands in Codex Rodriguez-Mondragón (2017-present), her ongoing series of maps, botanical illustrations, and landscape paintings.


The Effect Of An Invasive Species (Lantana Camara) And A Fast-Growing Herb (Acanthus Pubescens) On The Plant And Animal Communities In Kibale National Park, Uganda, Kathleen Bufka Aug 2025

The Effect Of An Invasive Species (Lantana Camara) And A Fast-Growing Herb (Acanthus Pubescens) On The Plant And Animal Communities In Kibale National Park, Uganda, Kathleen Bufka

Theses and Dissertations

Fast-growing plant species, like Lantana camara and Acanthus pubescens, could threaten biodiversity in Kibale National Park, Uganda. I surveyed plants and wildlife in areas where these plants were frequently encountered compared to those areas where they are infrequent. I found mixed results based on plant traits and the animals considered. My findings support management efforts on these two species to prevent forest degradation.


Gallic, Aconitic, And Crocetin Acids As Potential Tnf Modulators: An Integrated Study Combining Molecular Docking, Dynamics Simulations, Admet Profiling, And Gene Expression Analysis, Adolat Manakbayeva, Ahdrey P. Bogoyavlenskiy, Timur Kerimov, Igor Yershov, Pavel Alexyuk, Madina Alexyuk, Vladimir Berezin, Vyacheslav Dushenkov Jul 2025

Gallic, Aconitic, And Crocetin Acids As Potential Tnf Modulators: An Integrated Study Combining Molecular Docking, Dynamics Simulations, Admet Profiling, And Gene Expression Analysis, Adolat Manakbayeva, Ahdrey P. Bogoyavlenskiy, Timur Kerimov, Igor Yershov, Pavel Alexyuk, Madina Alexyuk, Vladimir Berezin, Vyacheslav Dushenkov

Publications and Research

Organic acids, as natural metabolites, play crucial roles in human metabolism and health. Tumor Necrosis Factor (TNF), a pivotal mediator in immune regulation and inflammation, is a key therapeutic target. We evaluated ten organic acids as TNF modulators using in silico molecular docking, followed by detailed ADMET (Absorption, Distribution, Metabolism, Excretion, and Toxicity) profiling and molecular dynamics (MD) simulations for three lead candidates: gallic, aconitic, and crocetin acids. Their effects on TNF gene expression were then assessed in vivo using a mouse leukocyte model. The in silico results indicated that crocetin had the highest TNF binding affinity (−5.6 to −4.6 …


Introduction To Sociology: Deviance And Crime, Dr. Marcia Morrison Ph.D. Jul 2025

Introduction To Sociology: Deviance And Crime, Dr. Marcia Morrison Ph.D.

Open Educational Resources

Abstract

This paper explores the multifaceted concepts of deviance and crime by synthesizing major theoretical perspectives and contemporary research findings. Beginning with the fluid and culturally contingent nature of deviance, the discussion highlights how social norms, historical context, and power structures define what is considered deviant behavior. It examines the influence of economic elites on moral and legal standards, drawing on Marxist analyses, and considers the impact of societal labeling on personal identity through Lemert’s labeling theory.

The paper then delves into biological foundations of criminality, reviewing Lombroso’s atavism theory and modern research on genetic predispositions, including twin, adoption, and …


Introduction To Sociology: Culture, Dr. Marcia Morrison Ph.D. Jul 2025

Introduction To Sociology: Culture, Dr. Marcia Morrison Ph.D.

Open Educational Resources

Abstract

A Synthesis of Sociological Perspectives on Culture and Social Evolution This paper provides an in-depth exploration of culture as a foundational element in the study of sociology, dissecting its central components—knowledge, language, symbols, values, norms, and material objects—and their profound impact on society. Through the examination of cultural integration and diversity, the analysis foregrounds the dynamic tensions between assimilation and the preservation of subcultures, illustrating how these forces shape identities, relationships, and social cohesion in contemporary contexts. The discussion offers nuanced insights into the processes by which dominant and minority cultures interact, negotiate power, and navigate the challenges of …


What Before Means: Teaching The English Pluperfect, Max Miller, Joseph C. M. Davis Jul 2025

What Before Means: Teaching The English Pluperfect, Max Miller, Joseph C. M. Davis

Publications and Research

This paper extends existing linguistic analyses of the English simple past tense (e.g., took) and pluperfect tense (e.g., had taken) by thoroughly examining communicative effects. It also proposes a pedagogical application. The analysis is based on authentic contextualized discourse (primarily a single published text). In distinction to the simple past, the pluperfect establishes a communicative link between a past time and an event before that time. In this way, the pluperfect makes conceptional connection (which could be termed "tethering") through temporal priority. The meaning of the pluperfect thus contributes to textual cohesion. The distinction made is communicative, not a matter …


A Comparative Study Of Epibionts And Age Structure Of Two East Coast Populations Of American Horseshoe Crabs, Mark L. Botton Phd, Christina P. Colon, Shiva Jeanbaptist, Kelvin Zaw, Robert E. Loveland Jul 2025

A Comparative Study Of Epibionts And Age Structure Of Two East Coast Populations Of American Horseshoe Crabs, Mark L. Botton Phd, Christina P. Colon, Shiva Jeanbaptist, Kelvin Zaw, Robert E. Loveland

Publications and Research

No abstract provided.


Medst 343w - Nonfiction Forms (8 Week Async Section), Ash Marinaccio Jun 2025

Medst 343w - Nonfiction Forms (8 Week Async Section), Ash Marinaccio

Open Educational Resources

In this course, we will explore how various forms of nonfiction storytelling represent reality and shape our understanding of the world. Over the semester, we will examine how “the real” is represented across different mediums, including theatre, film, photography, and literature. Through critical readings, case studies, creative exercises, and Brightspace discussions, we will examine the intricate interplay between truth, ethics, form, and authorship in documentary and nonfiction works.

The course is divided into five units. The first unit introduces foundational questions of ethics, authorship, and cultural responsibility in nonfiction storytelling. The following units focus on specific forms: documentary theatre, nonfiction …


Advances In Bone And Orthopedics 2025 – 5th Edition, Jean-Philippe Berteau, Laurent Pujo-Menjouet, Hélène Follet, Aurélie Levillain Jun 2025

Advances In Bone And Orthopedics 2025 – 5th Edition, Jean-Philippe Berteau, Laurent Pujo-Menjouet, Hélène Follet, Aurélie Levillain

Publications and Research

This volume brings together selected works from the 2025 Bone and Orthopedics Interdisciplinary Symposium (BONITOS), underscoring our community’s ongoing commitment to advancing research in biomechanics, bone health, and orthopedic science. The symposium unites leading experts from around the world, fostering collaboration and the exchange of ideas across disciplines. Organized in partnership with the French-speaking Society of Biomechanics, the French National Institute of Health and Medical Research (INSERM), the University of Lyon, the College of Staten Island of the City University of New York (CUNY), and the American Association of Physical Therapists (APTA) – Brooklyn Staten Island Chapter, BONITOS 2025 represents …


Artificial Intelligence And Astronomy: Lab Manual For Generative Ai-Based Learning Activities, Vasiliy Znamenskiy Jun 2025

Artificial Intelligence And Astronomy: Lab Manual For Generative Ai-Based Learning Activities, Vasiliy Znamenskiy

Open Educational Resources

This lab manual introduces community college students to the intersection of artificial intelligence (AI) and astronomy through hands-on, inquiry-based activities. It explores how generative AI platforms—ranging from text-based chat systems to image and video generators—can enhance scientific understanding, creativity, and critical thinking in space science education. Students engage with tools such as ChatGPT, Gemini, DALL·E, and Synthesia to formulate and evaluate astronomy-related questions, generate scientifically inspired visualizations, and produce dynamic representations of cosmic phenomena. Through structured exercises, the manual promotes digital literacy, fosters analytical skills, and illustrates how AI assists in astronomical research, including data analysis, image enhancement, spacecraft autonomy, …


Arts-Based Sustainability: From New York To Malawi, Martha B. Lerski Jun 2025

Arts-Based Sustainability: From New York To Malawi, Martha B. Lerski

Publications and Research

Recognizing that libraries serve multiple constituencies and subject areas, this chapter documents and advocates for development of transdisciplinary arts-based research (ABR) and culture-related projects linked to environmental challenges. Libraries contribute collections and spaces, as well as the research of library and information scientists. Libraries are currently among invisible contributors to sustainability planning and services. The chapter will link this invisibility to the value of what visual arts refer to as negative space elements in subjects ranging from traditional ecological knowledge to environmental science. Library collections, projects, and research contribute to education for sustainable development (ESD) as required to achieve the …


Political Sociology, Talha C. Issevenler Jun 2025

Political Sociology, Talha C. Issevenler

Open Educational Resources

This open-access textbook on political sociology introduces and problematizes the classical categories and parameters of the field. It explores the main approaches to the state and governance, while conceptualizing a turn toward network power. Specific chapters address political spacetime, violence, secrecy, social movements, politicization, interdisciplinarity, media, biopolitics, and event-analysis. Multimedia pedagogical exercises accompany the conceptual exposition.


Creative Coding Communities: Exploring The Relationship Between Scratch Use And Child Well-Being, Nikita Khalid Jun 2025

Creative Coding Communities: Exploring The Relationship Between Scratch Use And Child Well-Being, Nikita Khalid

Dissertations, Theses, and Capstone Projects

This international study assessed the relationship between the use of Scratch, the world's largest coding community for children, and child well-being. Specifically, the study focused on the presence of well-being indicators in the RITEC-8 framework (RITEC, 2024) including creativity, relationships, competence, and autonomy within Scratch users’ behaviors. The participants (N = 17,315) included children aged between 8 and 16 who used Scratch in 2023 and came from 29 countries. The study examined trends in Scratchers’ behaviors including project creation, sharing, studio curation, and socialization based on their country of origin, gender and age. The data were used to construct user …


Spirometry: For The Winds In Us, Kendall Allison Jun 2025

Spirometry: For The Winds In Us, Kendall Allison

Dissertations, Theses, and Capstone Projects

Spirometers are devices used to measure lung capacity. This capstone is a creative study of what restores our breathing aptitude as a response to the suffocating and alienating consequences of whiteness for people racialized as white. The project is a sequence of lyric essays. The first lyric essay frames whiteness as a condition of exile and examines the cultural and emotional currents that shore it up. I use exile as a frame to emphasize the intensity of the spiritual and cultural alienation that people racialized as white experience. I also contextualize the dis-ease of suicide in my own lineage, and …


Parvalbumin Interneuron-Oligodendrocyte Interactions In The Infralimbic Cortex Promote Extracellular Plasticity Mechanisms After Safety Learning, Lucy Emma Denholtz Jun 2025

Parvalbumin Interneuron-Oligodendrocyte Interactions In The Infralimbic Cortex Promote Extracellular Plasticity Mechanisms After Safety Learning, Lucy Emma Denholtz

Dissertations, Theses, and Capstone Projects

The ability to differentiate between threat and safety cues is essential for adaptive behavior, yet this process is disrupted in psychiatric disorders, such as post-traumatic stress disorder (PTSD), where safety cues fail to downregulate fear expression. To better understand the neurobiological mechanisms of safety learning, I investigate how safety conditioning vs contextual fear conditioning modify behavioral and cellular mechanisms in the infralimbic (IL) region of the medial prefrontal cortex (mPFC) at several time points after learning. Through this work, I identify a novel mechanism whereby safety learning promotes learning dependent neuro-glial interactions that promote conditions for plasticity in the mPFC. …


A Novel Closed Monoidal Structure On The Nucleus Of A Profunctor, Samantha K. Jarvis Jun 2025

A Novel Closed Monoidal Structure On The Nucleus Of A Profunctor, Samantha K. Jarvis

Dissertations, Theses, and Capstone Projects

We describe a novel closed monoidal structure on the nucleus of a profunctor enriched over a posetal category, a distinguished subcategory of the category of presheaves given by the invariant part of an adjunction induced by the profunctor. Our structure is motivated by a connection to a notion of type given by orthogonality. For specific examples, we consider the two-element enriching category {0,1} and the reals.


The "Self" In Crisis: A Study Of Audre Lorde's The Cancer Journals, Golnaz Salehkarimi Jun 2025

The "Self" In Crisis: A Study Of Audre Lorde's The Cancer Journals, Golnaz Salehkarimi

Dissertations, Theses, and Capstone Projects

In this thesis, I focus on The Cancer Journals and explore how Audre Lorde articulates the chaos followed by breast cancer in her life: what is the nature of the crises? What aspects of her life are largely affected by it? How it unsettles her understanding of time and place, how her daily life, work, relationships, and future plans get affected, and how her self-image and her agency and subjectivity are threatened. Relying on theories of women’s autobiographies, women’s writings, and illness narratives, I explore Lorde’s ways of writing about her body and emotions to regain her sense of self …


Environmental Enrichment Reduces Cue-Induced Reinstatement Of Heroin-Seeking Following Prolonged Use And Reverses Region-Specific Heroin-Induced Neuroadaptations, Apoorva Vashisht Jun 2025

Environmental Enrichment Reduces Cue-Induced Reinstatement Of Heroin-Seeking Following Prolonged Use And Reverses Region-Specific Heroin-Induced Neuroadaptations, Apoorva Vashisht

Dissertations, Theses, and Capstone Projects

Background: Relapse remains the greatest barrier to long-term recovery and the consequential rising overdose-related mortality in heroin use disorder (HUD). Currently available behavioral and pharmacological interventions fail to extend their benefits beyond the duration of the treatment. Additionally, opioid agonist-based medications accompany harmful neurobiological risks and propensity to promote further drug-seeking post-treatment. We have shown that environmental enrichment (EE), as a therapeutic strategy applied after drug intravenous-self administration (IVSA), can effectively facilitate abstinence and reduce reinstatement of drug-seeking in animal models of drug abuse. Moreover, dopamine receptors like D1 and D3, and mu-opioid (MO) receptors are well known for their …


Problems And Paradigms In The Central Sahel Of Africa, Georgia Graham Jun 2025

Problems And Paradigms In The Central Sahel Of Africa, Georgia Graham

Dissertations, Theses, and Capstone Projects

In Africa’s Central Sahel region—comprising of the countries of Mali, Niger, and Burkina Faso—environmental hardship, historical trauma, and contemporary conflict intersect with profound challenges of nation-building, state construction, and economic development. Situated in the semi-arid transitional zone between the Sahara Desert and sub-Saharan Africa, these landlocked states suffer from extreme geographical vulnerability. From the colonial period through to the present, these nations have experienced recurring droughts, persistent food insecurity, and entrenched poverty. Population growth has dramatically outpaced economic development; youth unemployment, limited educational opportunities, and scarce resources fuel social tension and potential conflict. Islamist insurgencies and increasingly violent ethnic conflicts …