Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Chulalongkorn University

Discipline
Keyword
Publication Year
Publication
Publication Type

Articles 7501 - 7530 of 37685

Full-Text Articles in Entire DC Network

The Novel Cyanoacrylate Based Fluoride Varnish, Narongrit Larpbunphol Jan 2022

The Novel Cyanoacrylate Based Fluoride Varnish, Narongrit Larpbunphol

Chulalongkorn University Theses and Dissertations (Chula ETD)

The important factors contributing to the effectiveness of fluoride varnish are the amount of fluoride ion release and the retention time of the varnish on the tooth surface. Commercial fluoride varnishes are susceptible to mechanical removal; therefore, patients are informed to avoid eating for a few hours and refrain from tooth brushing for 12–24 h, which results in patient inconvenience. However, the novel cyanoacrylate based fluoride varnish would not have these disadvantages. This study compared the daily fluoride ion release, abrasion resistance to brushing, and toxicity to human gingival fibroblasts (hGFs) between a newly-developed cyanoacrylate based fluoride varnish and Duraphat …

Go to article

Effects Of Academic Burnout On Study Engagement As Moderated By Resilience And Social Support: A Longitudinal Study, Suchada Ruengesri Jan 2022

Effects Of Academic Burnout On Study Engagement As Moderated By Resilience And Social Support: A Longitudinal Study, Suchada Ruengesri

Chulalongkorn University Theses and Dissertations (Chula ETD)

The purpose of this study was to examine the correlations between academic burnout, study engagement, resilience, and social support in the Thai education context. The study also aimed to investigate the effect of academic burnout on study engagement, moderated by resilience and social support after the transition from online learning to on-site learning due to the COVID-19 pandemic. Additionally, the study aimed to explore the effects of different types of social support on academic burnout, study engagement, and resilience. The current study included two data gathering occasions for hypothesis testing. The participants were undergraduate students aged between 18 to 25 …

Go to article

Effects Of Extraversion Personality Compatibility And The Michelangelo Phenomenon Via Facebook On Marital Satisfaction, Wanthip Chawaleemaporn Jan 2022

Effects Of Extraversion Personality Compatibility And The Michelangelo Phenomenon Via Facebook On Marital Satisfaction, Wanthip Chawaleemaporn

Chulalongkorn University Theses and Dissertations (Chula ETD)

Divorce rates in newlywed couples has been rising dramatically globally, particularly Thailand. Young adults who strive for success often seek romantic relationships that promote their personal growth in order to thrive. The Michelangelo phenomenon is a psychological concept which explains how romantic relationships facilitate each other’s goal pursuit via partner affirmation. This research explores the dyadic influence of the similarity effects of the Big Five’s extraversion trait and marital satisfaction mediated by the Michelangelo phenomenon via Facebook in Thai newlyweds who have been married less than 5 years. 70 dyads were collected in two waves with a 6 month interval. …

Go to article

Association Between Medical Insurance Choices And Healthcare Utilization Among Diabetes Patients In The People's Republic Of China : A Secondary Data Analysis, Duohui Chen Jan 2022

Association Between Medical Insurance Choices And Healthcare Utilization Among Diabetes Patients In The People's Republic Of China : A Secondary Data Analysis, Duohui Chen

Chulalongkorn University Theses and Dissertations (Chula ETD)

Since 2018, the universal medical insurance coverage rate has reached 95% in China. Due to the lack of medical and health resources and insufficient health service capacity of primary health care facilities in China, the biggest problem with the health system in China is overcrowding, especially in the utilization of outpatient services in secondary and tertiary hospitals. This study aimed to analyze the factors Association between Medical insurance Choices and healthcare Utilization among diabetes patients among patients of age >45 years in China. The logistic regression was used to assess the association between type of hospital of elder diabetic patients …

Go to article

Human Health Risk Assessment Of Heavy Metals In Roadside Dust Near Hydropower Dams Construction Areas In Wangduephodrang District Of Bhutan, Kinley Dorjee Jan 2022

Human Health Risk Assessment Of Heavy Metals In Roadside Dust Near Hydropower Dams Construction Areas In Wangduephodrang District Of Bhutan, Kinley Dorjee

Chulalongkorn University Theses and Dissertations (Chula ETD)

The concern over the heavy metal laden dust and its impact on human health has gained global importance over the decade. Exposure to roadside dust is associated with various acute and chronic health issues. Bhutan too is battling environmental health issues due to increasing anthropogenic and developmental activities such as hydropower dam construction. This study analyses the heavy metals concentrations in roadside dust near hydropower dam construction areas and assesses the noncancer and cancer risk of exposure to heavy metals laden dust through inhalation. This study was a cross sectional study. The roadside dust samples near hydropower dam construction in …

Go to article

The Effects Of Chinese Archery Arts Program On Core Executive Functions In Elementary School Children In Shanghai China : A Quasi-Experimental Study​, Jianjun Liu Jan 2022

The Effects Of Chinese Archery Arts Program On Core Executive Functions In Elementary School Children In Shanghai China : A Quasi-Experimental Study​, Jianjun Liu

Chulalongkorn University Theses and Dissertations (Chula ETD)

Objective: This study aimed to demonstrate the effect of a 12-week Chinese archery art program on core executive functions in preadolescent children in Shanghai, China. Methods: A quasi-experimental design was conducted in the present study. All 68 eligible participants were purposively assigned to a Chinese archery intervention group (45 minutes/session, 4 sessions/week, n=34) or extracurricular activity-based control group (45 minutes/session, 4 sessions/week, n=34); The whole study period included a 12-week treatment and a 6-week follow-up. The primary outcome was the performance of core executive functions (inhibition control, working memory, and cognitive flexibility), assessed with psychological paradigms: Fish Flanker Task, N-Back …

Go to article

Factors Association Of Discriminatory Attitudes Toward People Living With Hiv/Aids Among Adult Citizens In Myanmar : An Analysis Of 2015-2016 Myanmar Demographic And Health Survey, Pyae Phyo Thar Jan 2022

Factors Association Of Discriminatory Attitudes Toward People Living With Hiv/Aids Among Adult Citizens In Myanmar : An Analysis Of 2015-2016 Myanmar Demographic And Health Survey, Pyae Phyo Thar

Chulalongkorn University Theses and Dissertations (Chula ETD)

Myanmar, a developing nation, is still among the countries with the highest prevalence of HIV infection. Misconceptions, stigmatisation, and discrimination towards people living with HIV/AIDS (PLHIV) are significant factors that contribute to the prevention, transmission, and treatment of HIV. So, PLHIV-related stigma and discrimination are pervasive issues that significantly undermine public health efforts to prevent the spread of HIV and provide support for those living with the PLHIV. Despite its importance, the stigma and discrimination issues are often overlooked in national responses to PLHIV. In Myanmar, there are limited studies on discrimination against people living with HIV/AIDS, and it requires …

Go to article

แบบจำลองคุณภาพซอฟต์แวร์โอเพนซอร์ซเพื่อการวัดคุณภาพอย่างอัตโนมัติ, อัรกอม มะแดเฮาะ Jan 2022

แบบจำลองคุณภาพซอฟต์แวร์โอเพนซอร์ซเพื่อการวัดคุณภาพอย่างอัตโนมัติ, อัรกอม มะแดเฮาะ

Chulalongkorn University Theses and Dissertations (Chula ETD)

ปัจจุบันได้มีการนำเสนอแบบจำลองคุณภาพซอฟต์แวร์โอเพนซอร์ซหลายแบบจำลองเพื่อใช้ในการประเมินคุณภาพของซอฟต์แวร์โอเพนซอร์ซ แต่แบบจำลองเหล่านั้นมีข้อจำกัดเนื่องจากเป็นการประเมินตามความคิดส่วนตัวซึ่งต้องอาศัยผู้ใช้ในการประเมิน และแบบจำลองดังกล่าวต้องการข้อมูลจากหลากหลายแหล่ง เพื่อเสริมการประเมินคุณภาพซอฟต์แวร์โอเพนซอร์ซที่เป็นอยู่ให้ทำได้สมบูรณ์มากยิ่งขึ้น วิทยานิพนธ์นี้จึงได้นำเสนอแบบจำลองคุณภาพซอฟต์แวร์โอเพนซอร์ซใหม่ที่ชื่อว่าโอเอสเอส-เอคิวเอ็ม โดยมีเป้าหมายเพื่อการวัดคุณภาพซอฟต์แวร์โอเพนซอร์ซอย่างอัตโนมัติ แบบจำลองโอเอสเอส-เอคิวเอ็มได้นำเสนอตัววัดคุณภาพและเครื่องมืออัตโนมัติที่สามารถดึงข้อมูลเกี่ยวกับซอฟต์แวร์โอเพนซอร์ซจากกิตฮับ ซอร์ซโค้ด โซนาร์คิวบ์ และสแต็กเอกซ์เชนจ์ ทำให้สามารถกำหนดคะแนนคุณภาพของซอฟต์แวร์โอเพนซอร์ซได้ โอเอสเอส-เอคิวเอ็มได้รับการตรวจสอบจากวิศวกรซอฟต์แวร์ที่มีประสบการณ์ในการเลือกใช้ซอฟต์แวร์โอเพนซอร์ซ นอกจากนี้การจัดลำดับซอฟต์แวร์โอเพนซอร์ซโดยเครื่องมือโอเอสเอส-เอคิวเอ็มยังถูกนำไปเปรียบเทียบกับการจัดลำดับด้วยวิธีอื่น และพบว่าการจัดลำดับของโอเอสเอส-เอคิวเอ็มมีสหสัมพันธ์ระดับต่ำมากถึงปานกลางในทิศทางตรงกันข้ามกับวิธีจัดลำดับอื่น ๆ ตามความคิดเห็นและความนิยมของผู้ใช้ และมีสหสัมพันธ์ระดับปานกลางในทิศทางเดียวกันกับวิธีการจัดลำดับอื่นที่เน้นการตรวจสอบความมั่นคงที่ซอฟต์แวร์โดยตรง ทั้งนี้เนื่องจากโอเอสเอส-เอคิวเอ็มครอบคลุมปัจจัยคุณภาพหลายอย่างที่ไม่ได้ถูกพิจารณาโดยวิธีการจัดลำดับอื่น ๆ ดังกล่าว โอเอสเอส-เอคิวเอ็มจึงให้ข้อมูลด้านคุณภาพของซอฟต์แวร์โอเพนซอร์ซในเชิงลึกที่ดีกว่า

Go to article

Historical And Cultural Conditioning Of Building City's Image And Brand On The Example Of Lodz, Jolanta Bienkowska Jan 2022

Historical And Cultural Conditioning Of Building City's Image And Brand On The Example Of Lodz, Jolanta Bienkowska

Journal of Urban Culture Research

The aim of this article is to present, with the example of the city of Łódz, the impact of the narrative of a place led by myths and symbols on the perception of the image and brand positioning. Throughout the research procedure, the historical overview of Łódz was outlined in the forefront. Then, the content of 67 selected texts presenting genealogical myths were analyzed. The confrontation of historical content with myths made it possible to formulate a conclusion that the knowledge of the culture of a place, including myths and symbols, is a database for the analysis of the reasons …

Go to article

Sustainable Heritage City : An Empirical Study To Address Study Limitations In Previous Studies, Yazid Saleh, Hanifah Mahat, Mohmadisa Hashim, Nasir Nayan, Samsudin Suhaily, Mohamad Khairul Anuar Ghazali Jan 2022

Sustainable Heritage City : An Empirical Study To Address Study Limitations In Previous Studies, Yazid Saleh, Hanifah Mahat, Mohmadisa Hashim, Nasir Nayan, Samsudin Suhaily, Mohamad Khairul Anuar Ghazali

Journal of Urban Culture Research

This article reviews the previously published studies on sustainable heritage cities, and to derive lessons for further research. The research method used is document analysis. A total of 30 journal articles from leading databases published in the five (5) years (2016–2020) were selected using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) method. The results of the analysis can be broken down into the purpose of the study, methodology, selection of indicators and study area used in previous studies. The purpose of the past studies was to lead towards the development of sustainable heritage cities by using five …

Go to article

Technology And Music Production In Different Genres : Key Issues For A Significant Music Education, Adrien Faure-Carvallo, Diego Calderón-Garrido, Maria Del Mar SuáRez Jan 2022

Technology And Music Production In Different Genres : Key Issues For A Significant Music Education, Adrien Faure-Carvallo, Diego Calderón-Garrido, Maria Del Mar SuáRez

Journal of Urban Culture Research

This research stems from the assumption that knowing how sound technology works, as well as its features and limitations, can help us better understand the mainstream music styles and genres of the last decades. Consequently, the evolution of music recording is explored through a grounded analysis based on both published documents and on interviews with currently active music producers who are specialists in urban pop music, with the aim to collect enough data to support the need to increase the presence of sound technology in the teaching plans of Compulsory Secondary Education. After the data analysis, several didactic proposals are …

Go to article

The Musical Status Of The Roma In Primorje-Gorski Kotar County (Republic Of Croatia), Ines Cvitkovic Kalanjoš Jan 2022

The Musical Status Of The Roma In Primorje-Gorski Kotar County (Republic Of Croatia), Ines Cvitkovic Kalanjoš

Journal of Urban Culture Research

The Roma are the most populous minority group in Europe and have lived in the territory of the modern-day's Republic of Croatia for 700 years. This study is based on cultural and musical research in the area of Primorje-Gorski Kotar County, with an emphasis on the conurbations of Rijeka, Delnice, Crikvenica and Novi Vinodolski. This paper asks what the musical position of the Roma in Primorje-Gorski Kotar County is and how this is reflected in their music and in musical interaction with other Roma and non-Roma. The work gives an overview of the musical life of the Roma and takes …

Go to article

Fashion Collection Design Guidelines For Elderly Women In Bangkok Based On Thai Cultural Heritage, Atthaphon Ponglawhapun, Patcha Utiswannakul Jan 2022

Fashion Collection Design Guidelines For Elderly Women In Bangkok Based On Thai Cultural Heritage, Atthaphon Ponglawhapun, Patcha Utiswannakul

Journal of Urban Culture Research

Aging populations are increasing significantly worldwide, thereby generating aging societies. Certain product categories that interest elderly women in Bangkok include healthcare, lifestyle fashion, and culture. Cultural heritage are recognized as an important tool that can promote products and brand image. Fashion collection design based on cultural heritage concepts or storytelling have more opportunities to succeed in the fashion market. This research investigates two main points: (1) elderly women’s needs and preferences for fashion products and (2) conceptual guidelines for designing a fashion collection based on Thai cultural heritage. The sample population of this study included 439 elderly women from Bangkok. …

Go to article

Traditional Javanese Ethnic Songs : The Supporting Aspects Of Its Existence In The Local Community, Wadiyo Wadiyo, Slamet Haryono, Joko Wiyoso Jan 2022

Traditional Javanese Ethnic Songs : The Supporting Aspects Of Its Existence In The Local Community, Wadiyo Wadiyo, Slamet Haryono, Joko Wiyoso

Journal of Urban Culture Research

This study reveals the supporting aspects that make traditional Javanese songs preserved in the community the splendor of modern Javanese songs. This research applies qualitative design with a phenomenological approach. The research location is in Central Java. The researchers collected the data by observing, interviewing and collecting documents. The researchers validate the data based on triangulation system with interactive analysis. The results find that traditional Javanese songs still exist in its local society due to the strong psychological bonding of the society with their culture. Through traditional Javanese songs, cultural messages can be conveyed beautifully, inspire imagination and impart enjoyable …

Go to article

Qualitative Comparative Analysis In The Emotion Of Artistic Creativity : An Analysis Of Isolation In Painting, Fan Zhang, Tetriana Ahmed Fauzi, Muhammad Khizal Saat Jan 2022

Qualitative Comparative Analysis In The Emotion Of Artistic Creativity : An Analysis Of Isolation In Painting, Fan Zhang, Tetriana Ahmed Fauzi, Muhammad Khizal Saat

Journal of Urban Culture Research

This paper highlights the outcomes of the use of Qualitative Comparative Analysis (QCA) of isolation in paintings. A general literature review was conducted to analyze the connection between art, emotion and society in the existing research. Qualitative Comparative Analysis (QCA) is often used in the organization research of Humanities and Social Sciences and in this study, it is mainly used to analyze the expression of artist’s paintings. This paper makes a detailed analysis of the factors affecting the expression of isolation in paintings. Through the researcher's discussion among the selected Artist’s paintings, the researchers rely on Boolean algebra and take …

Go to article

Journal Policies, Jucr Staff Jan 2022

Journal Policies, Jucr Staff

Journal of Urban Culture Research

No abstract provided.

Go to article

Art As Soft Power, Bussakorn Binson Jan 2022

Art As Soft Power, Bussakorn Binson

Journal of Urban Culture Research

No abstract provided.

Go to article

Effects Of Cultural Processes On Heterotopic Spaces : The Case Of Bomonti, Istanbul, Ilgi Toprak, Orhan Hacihasanoglu Jan 2022

Effects Of Cultural Processes On Heterotopic Spaces : The Case Of Bomonti, Istanbul, Ilgi Toprak, Orhan Hacihasanoglu

Journal of Urban Culture Research

The cultural change model covers the cultural change processes and their effects on different spaces in the urban environment. Cultural processes constitute cultural change and may in turn alter the lifestyle of individual human beings and societies. The cultural change model for heterotopic spaces proposes that heterotopic spaces and their close environment physically change by the cultural processes that are taking place in the related society. A case study was conducted in the Bomonti region to obtain the cultural changes and their relations and effects on heterotopic spaces. The Bomonti beer factory which is defined as a heterotopic space in …

Go to article

Ar-Sculptures : Issues Of Technological Creation, Their Artistic Significance And Uniqueness, Tetiana Sovhyra Jan 2022

Ar-Sculptures : Issues Of Technological Creation, Their Artistic Significance And Uniqueness, Tetiana Sovhyra

Journal of Urban Culture Research

The threat of the Covid-19 epidemic quickly influenced the development of remote working tools using modern IT technologies. This has led to the emergence of a significant number of cultural practices for remote (virtual) use. Among them are experimental attempts to create volumetric virtual models that could be considered sculptures. At the same time, these developments have served the emergence of culturological problems: solving questions of uniqueness, artistic significance of works of this kind. In this regard, this article provides the results of a scientific study of the specifics of creating virtual sculptures, authorship issues and artistic significance of virtual …

Go to article

Visual Game Character Design To Engage Generation Z In An Effort To Develop Anti-Corruption Behavior In Indonesian Society, Eva Y, Noversar Jamarun Ms, Ari Leo B3, Cameron Malik Jan 2022

Visual Game Character Design To Engage Generation Z In An Effort To Develop Anti-Corruption Behavior In Indonesian Society, Eva Y, Noversar Jamarun Ms, Ari Leo B3, Cameron Malik

Journal of Urban Culture Research

This article aims to discuss the visual design of characters in a digital game about corruption and is intended to raise awareness of the danger of it for the Z generation. A visual character "in-game" is a better vehicle for spreading an anti-corruption message as each character has a different background and storyline representing their role and skills in a mission. The character, especially the villain figure, is based on a true story of a corruption case with a bit of modification, to make the message more easily absorbed by Gen Z players in Indonesia. Moreover, the main character in …

Go to article

The Transformative Power Of Fashion Within Beauty Pageants : The Case Of “Ghana’S Most Beautiful”, Scholastica Wompakeah Azuah, Ebenezer Kofi Howard, Benjamin Kwablah Asinyo Jan 2022

The Transformative Power Of Fashion Within Beauty Pageants : The Case Of “Ghana’S Most Beautiful”, Scholastica Wompakeah Azuah, Ebenezer Kofi Howard, Benjamin Kwablah Asinyo

Journal of Urban Culture Research

Pageants can be competitions for ladies with qualities of beauty determined by societal values and norms. In pageants’ orientation toward continuous change, they tend to achieve results through the engagement of fashion; the most visible medium of change found in aesthetics, culture and social events. Ghana's Most Beautiful Pageant’s engagement in traditional fashion has chalked up many successes. However, since its inception 15 years ago, little has been assessed on its transformative power. An exploratory sequential design was employed with a population comprised of viewers, fashion designers, organizers, judges, traditional rulers and contestants. Purposive sampling was used in selecting categories …

Go to article

The Devil In The Details : Analysing The Ethno-Cultural Blending In Malaysian Museum Buildings, Nor Hafizah Anuar, Muhammad Ilmam Tharazi, Yasmin Mohd Faudzi, Najah Md. Alwi Jan 2022

The Devil In The Details : Analysing The Ethno-Cultural Blending In Malaysian Museum Buildings, Nor Hafizah Anuar, Muhammad Ilmam Tharazi, Yasmin Mohd Faudzi, Najah Md. Alwi

Journal of Urban Culture Research

Museums are often used as a ‘visualizing technology’ to project the cultural identities of a nation or a particular demographic. The choice of building, either newly constructed or converted from an historic structure, places the importance of its architectural features to convey certain meanings over others. Using comparative analysis on multiple case studies as the main method for data collection, this paper identifies the architectural features on three selected building facade of Penang museums in relation to one another. It will then determine the cultural influences to explore the mechanism of ethno-cultural blending integrated into the architectural styles. Penang was …

Go to article

Conservation Of Row Houses In Old Commercial District Mekong Riverside Nakhon Phanom Province, Thailand, Pakorn Pattananurot, Suthon Khongsaktrakun Jan 2022

Conservation Of Row Houses In Old Commercial District Mekong Riverside Nakhon Phanom Province, Thailand, Pakorn Pattananurot, Suthon Khongsaktrakun

Journal of Urban Culture Research

The objectives of this research paper are; 1) to study the development of towns & commercial districts, 2) to study the architectural characteristics of the row houses and 3) to propose guidelines for their preservation by studying related theories & research, conducting field surveys & interviewing the owners or tenants. This study found that a group of Chinese immigrant merchants formed a commercial district and built row houses to trade, store and live by the Mekong Riverside & Sunthon Wichit Road. Traditional row houses can be divided into 3 types; 1) Mixed Chinese influenced style of a single storey 2) …

Go to article

Urban Identity Represented By Concept Stores Converted From Machiya In Central Kyoto, Supitsara Intaraksa, Nawit Ongsavangchai Jan 2022

Urban Identity Represented By Concept Stores Converted From Machiya In Central Kyoto, Supitsara Intaraksa, Nawit Ongsavangchai

Journal of Urban Culture Research

The city grid plan of Kyoto gave birth to rectangle street blocks and long narrow land plots for the layout of machiya, a traditional townhouse. From the last two decades, many old buildings in Kyoto including machiya were restored for contemporary use as concept store which widely known for its distinctive design that can represent Kyoto's urban features. This research aims to clarify the relationship between modern concept stores and the traditional urban fabric of Kyoto by selecting nine concept stores as case studies to collect data on-site for doing content analysis from their spatial planning to physical design; …

Go to article

Music And Art In Political Campaigns, Bussakorn Binson Jan 2022

Music And Art In Political Campaigns, Bussakorn Binson

Journal of Urban Culture Research

No abstract provided.

Go to article

Formulation Development Of Drug Loaded Cyclodextrin-Based Nanoparticles For Ocular Delivery, Hay Man Saung Hnin Soe Jan 2022

Formulation Development Of Drug Loaded Cyclodextrin-Based Nanoparticles For Ocular Delivery, Hay Man Saung Hnin Soe

Chulalongkorn University Theses and Dissertations (Chula ETD)

The development of topical eye drops for treatment of glaucoma and fungal keratitis is still challenging. Due to low aqueous solubility of drugs and the presence of ocular barriers, it is difficult to achieve effective therapeutic drug levels in targeted ocular tissues. In this present study, cyclodextrin (CD)-based nanoparticles (NPs) and synthetic CD-polymers were introduced to overcome these drawbacks and evaluated for their safety and efficacy. γ-Cyclodextrin (γCD) was able to increase the solubility of intraocular pressure lowering drugs, i.e., irbesartan (IRB) and candesartan cilexetil (CAC). The addition of Soluplus® significantly enhanced the complexation efficiencies of IRB/γCD and CAC/γCD complexes. …

Go to article

Development Of Paper-Based Electrochemical Device For Detection Of Biomarker Of Infectious Diseases, Chawin Srisomwat Jan 2022

Development Of Paper-Based Electrochemical Device For Detection Of Biomarker Of Infectious Diseases, Chawin Srisomwat

Chulalongkorn University Theses and Dissertations (Chula ETD)

This dissertation focused on the development of novel point-of-care (POC) testing devices with luminescent and electrochemical detection techniques for the detection of nucleic acid in infectious diseases. This content can be classified into two main parts: (1) the development of a POC sensing device with luminescent detection, and (2) the development of POC testing devices with electrochemical detection. In the first part, an alternating current electroluminescent device for the detection of HIV and HCV cDNA with a label-free platform was developed. The luminosity of the device increased in the presence of the target DNA. The negative charge on the backbone …

Go to article

Reductant-Free Ozonolysis Of Alkenes : Acid-Catalyzed Hydration Of Criegee Intermediate, Joshua Osorio Jan 2022

Reductant-Free Ozonolysis Of Alkenes : Acid-Catalyzed Hydration Of Criegee Intermediate, Joshua Osorio

Chulalongkorn University Theses and Dissertations (Chula ETD)

The in-water ozonolysis of alkenes is an emerging alternative method to the conventional ozonolysis since it eliminates the requirement for a reductive work-up step using expensive and hazardous reductants such as dimethyl sulfide, triphenylphosphine, and zinc in acetic acid. Despite its greenness, it still suffers from competing reactions (such as the Baeyer-Villiger reaction and advanced oxidation process) and poor yields of the carbonyl product. Herein, we report the effect of adding an acid as a catalyst in the formation of carbonyl products from in-water ozonolysis. Styrenes and olefinic natural products were dissolved in a mixture of 95:5 (v/v) acetone-water (c.a.[c] …

Go to article

Metabolic Alterations For Increased Glycogen And Poly(3-Hydroxybutyrate) Production In Cyanobacterium Synechocystis Sp. Pcc 6803, Nannaphat Sukkasam Jan 2022

Metabolic Alterations For Increased Glycogen And Poly(3-Hydroxybutyrate) Production In Cyanobacterium Synechocystis Sp. Pcc 6803, Nannaphat Sukkasam

Chulalongkorn University Theses and Dissertations (Chula ETD)

Cyanobacteria are a potential biofactory for biopolymer production because they can convert greenhouse gas carbon dioxide and light to useful biopolymers. Synechocystis sp. PCC 6803 is a widely used model cyanobacterium due to its simple genetic information and known biochemistry metabolism. This research aims to develop strategies to increase the accumulation and productivity of biopolymers, poly(3-hydroxybutyrate) (PHB) and glycogen, which are required in current and future industries. Three strategies, namely genetic engineering, metabolic inhibition using chemical treatment, and culture media optimization (regarding nitrogen supply), were studied, as well as their combination to increase the PHB and/or glycogen production. Genetic engineering …

Go to article

Anti-Melanogenic Compounds From Artocarpus Lakoocha, Patsarunnut Dachma Jan 2022

Anti-Melanogenic Compounds From Artocarpus Lakoocha, Patsarunnut Dachma

Chulalongkorn University Theses and Dissertations (Chula ETD)

In this study, a purification of the methanol crude extract of A. lakoocha twigs resulted in the isolation of eight compounds (1–8). These compounds were identified as ß-amyrin acetate (1), lupeol (2), cudraflavone A (3), cycloartocarpin (4), brosimone I (5), artocarpin (6), oxyresveratrol (7), and hopeafuran (8). Their structures were elucidated through the interpretation of spectroscopic data and comparison with those previously reported. Subsequently, all the isolated compounds were evaluated for their anti-melanogenic activity. The results showed that fraction D (IC50: 12.04 ± 0.02 µg/mL) displayed potent inhibitory melanogenic activity in B16F10 melanoma cells, compared to positive control, arbutin (IC50: …

Go to article

First Prev Next Last