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Improving Knowledge, Attitude, And Compliance Of Hand Hygiene Of Iranian Healthcare Workers: A Pilot Study Using Reminder Card, Zahra Chegini, Ifeoluwapo Kolawole, Prashant Singh, Farzaneh Alikhah, Yalda Rasti, Zahra Motazedi Aug 2022

Improving Knowledge, Attitude, And Compliance Of Hand Hygiene Of Iranian Healthcare Workers: A Pilot Study Using Reminder Card, Zahra Chegini, Ifeoluwapo Kolawole, Prashant Singh, Farzaneh Alikhah, Yalda Rasti, Zahra Motazedi

Journal of Health Research

Background: Compliance rate of hand hygiene practice by healthcare workers has been observed to be universally low despite its importance, simplicity and cost-effectiveness in preventing the spread of infectious diseases in the healthcare settings. This study aimed to improve healthcare workers’ knowledge, attitudes, and compliance with hand hygiene by using reminder cards displayed by patients.

Method: This before-after interventional study was carried out in 2019 among healthcare workers of a hospital in Tabriz, Iran. The intervention was a ‘Reminder Card’ showed by patients to remind healthcare workers to clean their hands. Participants' knowledge and attitude about hand hygiene and …


How Area Health Management Leads To Improved Equity In Health: A Scoping Review, Methinee Intarates, Teerapon Dhippayom, Nilawan Upakdee, Vinai Leesmidt, Jain Weraphong, Mukdarut Bangpan Aug 2022

How Area Health Management Leads To Improved Equity In Health: A Scoping Review, Methinee Intarates, Teerapon Dhippayom, Nilawan Upakdee, Vinai Leesmidt, Jain Weraphong, Mukdarut Bangpan

Journal of Health Research

Background: The scoping review of published studies aims to explore what practices and processes can improve equity (horizontal and vertical) in countries that adopted Area Health Management (AHM) utilizing the “Six Building Blocks Plus” (SBBP) concept.

Method: An electronic search was conducted from the inception to January 27, 2021, from 6 databases (Embase, Social Sciences, Web of Science, PubMed, CINAHL, and WHO) and the gray literature. The inclusion criteria were AH, SBBP, and equity. Data extraction was using a standardized data collection form.

Results: This scoping review includes 63 full-text studies. SBBP are identical in the horizontal and vertical equity. …


Factors That Influence Individual And Community Behavioural Change Regarding Environmental Health, Obadia Kyetuza Bishoge, Ademola Kabir Aremu, Dickson Dare Ajayi, Sayoki Godfrey Mfinanga Aug 2022

Factors That Influence Individual And Community Behavioural Change Regarding Environmental Health, Obadia Kyetuza Bishoge, Ademola Kabir Aremu, Dickson Dare Ajayi, Sayoki Godfrey Mfinanga

Journal of Health Research

Background: Increased environmental health problems have led to a rise in concern among individuals, as well as government and non-governmental organizations to tackle them. To achieve this, there is a need for behavioural change among individuals and the community on environmental health at local to international levels. The purpose of this paper is to critically explore the factors that influence personal and community behavioural change regarding environmental health.

Method: The study is a systematic review of the literature on the factors that influence personal behavioural change regarding environmental health based on the relevant studies published between 2005 and 2020. We …


Factors Influencing Sexuality, Gender And Norms Of Adolescent: A Cross-Sectional Study Among Adolescent In Indonesia, Tantut Susanto, Tirta Amerta Isworo, Dewi Rokhmah Aug 2022

Factors Influencing Sexuality, Gender And Norms Of Adolescent: A Cross-Sectional Study Among Adolescent In Indonesia, Tantut Susanto, Tirta Amerta Isworo, Dewi Rokhmah

Journal of Health Research

Background: The current study explored the factors related to the sexuality, gender, and norms among Indonesian adolescents via structural equation modelling.

Method: A cross-sectional design was performed among 394 adolescents from August to October 2020 in East Java of Indonesia. A self-administered questionnaire measured factors that influenced sexuality, gender, and norms of adolescents. We used smart PLS (Partial Least Squares) to analyze the data.

Results: Two correlations emerge among independent variables, namely sociodemographic of adolescent and knowledge of reproductive health (RH) and human immunodeficiency virus (HIV) (p< 0.001) and sociodemographic of parents and family structure and function of RH (p< 0.001). Sociodemographic of parents (p= 0.003), knowledge of RH and HIV (p= 0.012), and family structure and function of RH (p= 0.006) were directly related to sexuality, gender, and norms of adolescent. Sociodemographic of adolescents (p= 0.031) and parents (p= 0.024) were indirectly related to the sexuality, gender, and norms of adolescent through knowledge of RH and HIV. Our model explains 39.9% of the variance in sexuality, gender, and norms of adolescents.

Conclusion: Factors that influence sexuality, gender, and norms of the adolescent …


Depression And Related Factors Among Health Science Students In Da Nang, Vietnam: A Cross-Sectional Study, Ngoc Thi Nhu Hoang, Ann Jirapongsuwan, Sukhontha Siri Aug 2022

Depression And Related Factors Among Health Science Students In Da Nang, Vietnam: A Cross-Sectional Study, Ngoc Thi Nhu Hoang, Ann Jirapongsuwan, Sukhontha Siri

Journal of Health Research

Background: This paper aimed to investigate the prevalence of depression and related factors among health science students in Da Nang, Vietnam.

Method: A cross-sectional study was undertaken among 401 undergraduate students. Depression was measured using the Centre for Epidemiological Studies Short Depression Scale. Bivariate and multivariate logistic regression was applied to identify any associations.

Results: Findings indicated that the prevalence of depression among students was 41.6%. Factors associated with the depression were studying in second year (aOR=3.15, 95%CI: 1.24-7.99), studying in third year (aOR=2.60, 95%CI: 1.056-6.42), poor health status (aOR= 2.57, 95%CI: 1.54-4.29), low and moderate parents’ relationships (aOR=12.41, 95%CI: …


Delayed Pre-Hospital Time In Acute Coronary Syndrome Patients And Associated Factors In A Hospital In Southern Thailand, Thareerat Ananchaisarp, Siriwimon Tantarattanapong, Supakit Satayukun, Kamonluk Thepuatrakul, Nuteua Techapattanakorn, Noppawit Limwattanalert, Nitchada Mettraiyasakul, Siwa Rattanakitkoson, Abhisit Chuaboon Aug 2022

Delayed Pre-Hospital Time In Acute Coronary Syndrome Patients And Associated Factors In A Hospital In Southern Thailand, Thareerat Ananchaisarp, Siriwimon Tantarattanapong, Supakit Satayukun, Kamonluk Thepuatrakul, Nuteua Techapattanakorn, Noppawit Limwattanalert, Nitchada Mettraiyasakul, Siwa Rattanakitkoson, Abhisit Chuaboon

Journal of Health Research

Background: Acute coronary syndrome (ACS) is currently the leading cause of morbidity and mortality worldwide. The prognosis of ACS treatment outcome depends on the speed of reperfusion after a heart attack; wherein, one of the associated factors is pre-hospital time.

Method: A retrospective study was conducted in ACS patients, who visited the emergency room of a tertiary hospital; from 1st January to 31st December 2020. The primary outcome was pre-hospital time; and secondary outcome was factors associated with delayed pre-hospital time (≥ 2 hours) that were analyzed by using logistic regression.

Results: The Median age of …


Development Of Wefit Screening Tool For Assessing Pre-Exercise Fitness Level For Older Adults In Peninsular Malaysia, Divya Vanoh, Arimi Fitri Mat Ludin, Suzana Shahar, Shahrul Azman Mohd Noah, Zahara Abdul Manaf, Noorlaili Mohd Tohit Aug 2022

Development Of Wefit Screening Tool For Assessing Pre-Exercise Fitness Level For Older Adults In Peninsular Malaysia, Divya Vanoh, Arimi Fitri Mat Ludin, Suzana Shahar, Shahrul Azman Mohd Noah, Zahara Abdul Manaf, Noorlaili Mohd Tohit

Journal of Health Research

Background: Pre-exercise screening is important to identify the fitness level of older adults prior to performing exercise. This study aimed to develop a screening tool for identifying older adults with poor physical fitness prior to exercising.

Method: Participants involved 2315 older adults from four states in Peninsular Malaysia. Several social and health parameters were investigated, and fitness level was assessed using hand grip strength. Receiver operating curve (ROC) analysis was chosen to determine the cut-off point, sensitivity, specificity, positive predictive value (PPV) and Youden`s Index of the screening tool.

Results: Age, sex, waist circumference, hypertension, diabetes mellitus and fasting blood …


Administrative Data Improves Quality Of Cervical Pre-Cancer Surveillance In Davidson County, Tennessee, United States, Sheelah Blankenship, Manideepthi Pemmaraju, Edward Mitchel, Tiffanie M. Markus, Marie R. Griffin, Jessica L. Castilho Aug 2022

Administrative Data Improves Quality Of Cervical Pre-Cancer Surveillance In Davidson County, Tennessee, United States, Sheelah Blankenship, Manideepthi Pemmaraju, Edward Mitchel, Tiffanie M. Markus, Marie R. Griffin, Jessica L. Castilho

Journal of Health Research

Background: Accurate data are critical for public health surveillance yet can be challenging to ensure. The Tennessee (TN) HPV Vaccine IMPACT Project aims to assess the effectiveness of the human papillomavirus (HPV) vaccine in prevention of cervical cancer and high-grade dysplasia through laboratory reporting of pathology results among Davidson County women. This project assessed feasibility and value of use of administrative sources for improved data quality and completeness of high-grade cervical events in TN HPV-IMPACT between 2013-2017.

Method: We queried three administrative data systems (Hospital Discharge Data System, Ambulatory Surgical Treatment Center, and Tennessee Medicaid [TennCare]) for eligible women with …


An Overlooked Problem: A Qualitative Meta-Synthesis From Experience Of Men With Diabetic Erectile Dysfunction, Junjira Seesawang, Pulawit Thongtaeng Aug 2022

An Overlooked Problem: A Qualitative Meta-Synthesis From Experience Of Men With Diabetic Erectile Dysfunction, Junjira Seesawang, Pulawit Thongtaeng

Journal of Health Research

Background: ED is negatively associated with men’s sexual function capacity, emotional, intimate relationship and particularly psychological well-being. The purpose of this study was to synthesize qualitative findings which explain the experiences of men with diabetes who have erectile dysfunction.

Method: A meta-synthesis was performed. A search for qualitative studies published in English from 2010 to 2020 was conducted using PubMed, CINAHL, PsycInfo, and Science Direct databases. The main key words included: experience, men/male patient, erectile dysfunction, diabetes, diabetic erectile dysfunction, and qualitative research. Inductive and interpretative technique was used to analyze and synthesize findings from qualitative studies and reviewed by …


Acculturation Strategies Of The Recent Wave Of Indonesian Migrants In Thailand, Muhammad Zamal Nasution, Rosalia Sciortino, Sakkarin Niyomsilpa, Sureeporn Punpuing Aug 2022

Acculturation Strategies Of The Recent Wave Of Indonesian Migrants In Thailand, Muhammad Zamal Nasution, Rosalia Sciortino, Sakkarin Niyomsilpa, Sureeporn Punpuing

Journal of Health Research

Background: The rapid increase of Indonesian migrants to Thailand in the last two decades due to greater regional integration, transport connectivity, and internationalization of education. Different religion, socio-culture, and other sociodemographic factors might affect their adaptation to the Thai society.

Method: A mixed-method design was employed for data collection. The quantitative data were derived from an online survey of 268 respondents, while the qualitative data came from literature review, in-depth interviews, focus group discussion, and direct observation.

Results: Indonesian migrants tended to opt for an integration strategy and to a lesser extent a separation strategy, with assimilation and marginalization ranking …


A Systematic Review Of The Use Of Simulated Client Method In Examining Medicine Price, Kah Seng Lee, Yaman Walid Kassab, Nur Akmar Taha, Zainol Akbar Zainal Aug 2022

A Systematic Review Of The Use Of Simulated Client Method In Examining Medicine Price, Kah Seng Lee, Yaman Walid Kassab, Nur Akmar Taha, Zainol Akbar Zainal

Journal of Health Research

Background: Simulated patient method has been frequently utilised to explore the healthcare provider’s behaviour, services information, and its quality of services. This study was aimed to systematically identify and review studies conducted using simulated client/patients that examine medicine selling prices in various healthcare settings.

Method: We searched Pubmed, OVID, Scopus, Ebsco (Medline) and ProQuest for papers reporting on simulated patient studies, specifying drug or pharmaceutical pricings. Randomized controlled trials, non-randomized controlled trials, longitudinal studies, cohort or case–control studies, and descriptive studies were included.

Results: A total of 19 papers from 13 countries from all regions of the world were included …


Subchronic Dermal Toxicity Study Of Tithonia Diversifolia (Hemsley) A. Gray Gel Formulation In Wistar Rats, Muflihah Rizkawati, Mae Sri Hartati Wahyuningsih, Setyo Purwono, Dwi Aris Agung Nugrahaningsih, Abdul Karim Zulkarnain Aug 2022

Subchronic Dermal Toxicity Study Of Tithonia Diversifolia (Hemsley) A. Gray Gel Formulation In Wistar Rats, Muflihah Rizkawati, Mae Sri Hartati Wahyuningsih, Setyo Purwono, Dwi Aris Agung Nugrahaningsih, Abdul Karim Zulkarnain

The Thai Journal of Pharmaceutical Sciences

Background: Tithonia diversifolia has been widely developed as an anticancer therapy. Our previous study before showed that T. diversifolia was able to inhibit cell proliferation and collagen accumulation of keloid fibroblasts and decrease the index of rabbit scar hypertrophy. The acute dermal toxicity study of T. diversifolia gel formulation did not show toxic effect for 14 days and the LD50 was estimated more than 2%. However, toxicity data subchronic dermal toxicity study was not available for this T. diversifolia gel formulation. Objectives: Our study aimed to evaluate the subchronic dermal toxicity of T. diversifolia gel formulation in rats. Materials and …


Preparation And Stability Of Fluocinolone Acetonide Premicroemulsion Concentrates And Microemulsions For Oral Lichen Planus Treatment, W. Muangsiri, P. Chukaewrungroj, Pornpen Werawatganone Aug 2022

Preparation And Stability Of Fluocinolone Acetonide Premicroemulsion Concentrates And Microemulsions For Oral Lichen Planus Treatment, W. Muangsiri, P. Chukaewrungroj, Pornpen Werawatganone

The Thai Journal of Pharmaceutical Sciences

Purpose: Fluocinolone acetonide (FA) preparations were developed in the forms of premicroemulsion concentrates and microemulsions and their stabilities were evaluated. Materials and Methods: A pseudoternary diagram of clove oil, surfactant mixture (containing polysorbate80: Polyethylene glycol 400 [PEG400] at the ratio of 2:1), and water was constructed for the formulation of FA premicroemulsion concentrates and microemulsions. Physical properties and chemical stabilities of the preparations were monitored in the absence and presence of three antioxidants. Their beyond-use dates were determined. Results and Discussion: The premicroemulsion concentrates and microemulsions containing polysorbate 80, PEG400, and clove oil successfully improved FA solubility. Average diameters of …


Design, Development, And Characterization Of Brinzolamide And Brimonidine Tartrate Nanoemulsion For Ophthalmic Drug Delivery, Bhavin R. Choradiya, Sanjay B. Patil Aug 2022

Design, Development, And Characterization Of Brinzolamide And Brimonidine Tartrate Nanoemulsion For Ophthalmic Drug Delivery, Bhavin R. Choradiya, Sanjay B. Patil

The Thai Journal of Pharmaceutical Sciences

Aim: The current investigation work sums up the enumerating improvement and depiction of brinzolamide and brimonidine tartrate ophthalmic nanoemulsion giving widened helpful effect and improved visual penetration for treating glaucoma. Methodology: Nanoemulsion was formulated using polysorbate 80, castor oil and glycerol using the continuous emulsification technique. Preliminary batches were screened subject to in vitro medication release, globule size, zeta potential, and stability with regards to accelerated and long time. Nanoemulsions were evaluated for ex vivo optical irritancy using the hen’s egg chorioallantois membrane test model. Results: Screened nanoemulsion batches showed a low mean globule width (<220 nm), higher penetrability (>75%) in comparison with …


A New Antidiabetic Polyherbal Formulation For Diabetes, Sadish Kumar Shanmugam, Praveen Kumar Gaur, Deepak Kumar Aug 2022

A New Antidiabetic Polyherbal Formulation For Diabetes, Sadish Kumar Shanmugam, Praveen Kumar Gaur, Deepak Kumar

The Thai Journal of Pharmaceutical Sciences

Background: Synergism is a well-known concept in Herbal therapies. Polyherbal aqueous extract (PH-AE) containing Gymnema sylvestre (GS), Momordica charantia, Syzygium cumini, and Mangifera indica was evaluated for Antidiabetic activity. Objective: In our continuous research, an attempt has been made to explore GS aqueous extract (GS-AE) and its Polyherbal composite for diabetes to achieve greater efficacy. Methods: The antidiabetic activity was assessed in Streptozotocin induced diabetic rats and histopathological changes in Pancreas were documented after screening acute toxicity of both extracts. Results: Chromatographic separation and identification of GS-AE revealed the presence of Saponins and glycosides, which have also been confirmed in …


Diversity And Lipolytic Activity Of Lactic Acid Bacteria Isolated From Fermented Foods And Plant Materials In Thailand, Sujitra Techo, Nattakorn Kuncharoen, Somboon Tanasupawat Aug 2022

Diversity And Lipolytic Activity Of Lactic Acid Bacteria Isolated From Fermented Foods And Plant Materials In Thailand, Sujitra Techo, Nattakorn Kuncharoen, Somboon Tanasupawat

The Thai Journal of Pharmaceutical Sciences

Lactic acid bacteria (LAB) originated from fermented foods, are generally known to possess the lipolytic activity which provides the desirable flavor of the products. However, the researches on their lipolytic activity are limited. Therefore, LAB with lipolytic activity derived from traditional fermented foods and plants in Thailand were isolated and identified based on the phenotypic characteristics and 16S rRNA gene sequences. The isolates were identified as Lactiplantibacillus pentosus (four isolates), Lactiplantibacillus plantarum (three isolates), Limosilactobacillus fermentum (four isolates), Enterococcus hirae (two isolates), and each isolate of Lactiplantibacillus paraplantarum, Companilactobacillus tucceti, Companilactobacillus farciminis, Lacticaseibacillus porcinae, Lactobacillus amylovorus, Pediococcus pentosaceus, and Enterococcus …


Complexity Of Implementing Harm Reduction Services In Community Hospitals: A Two-Phase Qualitative Study, Kanittha Nimsakul, Puckwipa Suwannaprom, Siritree Suttajit Aug 2022

Complexity Of Implementing Harm Reduction Services In Community Hospitals: A Two-Phase Qualitative Study, Kanittha Nimsakul, Puckwipa Suwannaprom, Siritree Suttajit

The Thai Journal of Pharmaceutical Sciences

Objective: Regardless of effective harm reduction services (HRS) in Thanyarak Hospital, difficulties exist while implementing them in community hospitals. This study aimed to investigate the complexities of HRS implementation in two community hospitals in Mae Hong Son. Methods: Phase 1, in-depth interviews were conducted with 21 participants to investigate the complexity of HRS dissemination. An interview guide was developed from the seven domains of the Non-adoption, Abandonment, Scale-up, Spread, and Sustainability framework, and thematic analysis was used. Phase 2 involved two rounds of a Delphi technique with 17 experts to evaluate the HRS’s complexity level (complex, complicated, simple). Results: Although …


The Successful Treatment Of Brevundimonas Diminuta Using Ceftriaxone, In A Patient On Continuous Ambulatory Peritoneal Dialysis: A Case Report And Literature Review, Sukrit Kanchanasurakit, Natnicha Woranithipokin, Piyakamol Teeranaew, Natthawee Kaewrattanapatthama, Chotirat Nakaranurack Aug 2022

The Successful Treatment Of Brevundimonas Diminuta Using Ceftriaxone, In A Patient On Continuous Ambulatory Peritoneal Dialysis: A Case Report And Literature Review, Sukrit Kanchanasurakit, Natnicha Woranithipokin, Piyakamol Teeranaew, Natthawee Kaewrattanapatthama, Chotirat Nakaranurack

The Thai Journal of Pharmaceutical Sciences

Brevundimonas diminuta (B. diminuta) is found in the health-care environment and in the community. At present, there are few reports of infections caused by this microorganism, especially in patients undergoing continuous ambulatory peritoneal dialysis (CAPD). A 44-year-old woman undergoing CAPD was diagnosed with a B. diminuta infection. Ceftriaxone was given both intravenously and intraperitoneally. After treatment with ceftriaxone, the peritoneal dialysis fluid white cell count, neutrophil count, and symptoms improved. To the best of our knowledge, this is the first case report of a B. diminuta infection in a patient had undergoing CAPD in Thailand


Impact Of Clinical Pharmacist Intervention On Medication Adherence In Patients With Cardiovascular Disease, S. Lavanya, Netal Patel, Arnav Purani, Kajal Patel Aug 2022

Impact Of Clinical Pharmacist Intervention On Medication Adherence In Patients With Cardiovascular Disease, S. Lavanya, Netal Patel, Arnav Purani, Kajal Patel

The Thai Journal of Pharmaceutical Sciences

Background: Cardiovascular diseases (CVDs) are a category of heart and blood vessel disorders that include coronary disorders, cerebrovascular diseases, rheumatic pain, and other conditions. One of the major risk factors for CVDs is high blood pressure (BP). Furthermore, it is poorly managed due to a lack of understanding of hypertension, a lack of proper primary care, and a lack of follow-up. The patient education improves the patient’s response to the disease and its management and their quality of life. Objectives: The objectives of this study were to evaluate the effect of clinical pharmacist intervention by the provision of patient counseling, …


Development And Optimization Of Polyherbal Formulation For Antiurolithiatic Activity Using Box Behnken Statistical Design, Tejal Gandhi, Vaidehi Patel, Saloni Dalwadi, Vaishali Thakkar Aug 2022

Development And Optimization Of Polyherbal Formulation For Antiurolithiatic Activity Using Box Behnken Statistical Design, Tejal Gandhi, Vaidehi Patel, Saloni Dalwadi, Vaishali Thakkar

The Thai Journal of Pharmaceutical Sciences

Background: The objective of the present investigation was to design and evaluate the antiurolithiatic activity of extract of Tribulus terrestris, Bryophyllum pinnatum, and Cyperus rotundus on ethylene glycol-induced urolithiasis in Wistar albino rats using Box Behnken Design. To induce urolithiasis, 0.75% w/v ethylene glycol was administered orally to the rats for 28 days. Cystone 750 mg/kg was selected as the reference standard as a preventive dose. On the 28th day, urine discharged in 24 h was collected and subjected for estimation of various biochemical parameters which were evaluated using urine, serum, and kidney homogenate. The kidneys were also sectioned and …


Antioxidant Status, Antihyperlipidemic Activity, And Serum Electrolyte Levels In Dexamethasone-Induced Oxidative Stress In Wistar Rats Treated With Vitamin E, Idara Asuquo Okon, Justin Atiang Beshel, Daniel Udofia Owu Aug 2022

Antioxidant Status, Antihyperlipidemic Activity, And Serum Electrolyte Levels In Dexamethasone-Induced Oxidative Stress In Wistar Rats Treated With Vitamin E, Idara Asuquo Okon, Justin Atiang Beshel, Daniel Udofia Owu

The Thai Journal of Pharmaceutical Sciences

Objectives: Dexamethasone (Dex) is an anti-inflammatory drug with serious side effects. The aim of this study was to investigate, antioxidants status, antihyperlipidemic activity, and serum electrolyte levels of rats treated with Vitamin E in Dex-induced oxidative stress. Materials and Methods: Wistar rats of both sexes were assigned to four groups (n = 6). The control group was fed with standard rat feed and water, while Dex group received 30 μg/kg of Dex. Vitamin E group received 300 IU/kg of vitamin E, while Dex + Vitamin E group received 30 μg/kg of Dex and 300 IU/kg of vitamin E. After 14 …


Silymarin And Oral Cancer: A Review On Clinical And Analytical Reports, Ramya Jonnalagadda, C. Vinodhini Aug 2022

Silymarin And Oral Cancer: A Review On Clinical And Analytical Reports, Ramya Jonnalagadda, C. Vinodhini

The Thai Journal of Pharmaceutical Sciences

Oral cancer is the sixth-largest kind globally of cancer and a major health issue in India as well and affects a large population that is very vulnerable to recurrences and a lower survival rate among all the other malignancies. Milk thistle is a phytochemical herb of interest that has been used as folk medicine since ancient times. Due to its potential benefits, the pharmaceutical industrial world is widely using silymarin (an active component of milk thistle) for commercial preparations. Knowing the quantity and identity of active components is of utmost importance. Therefore, robust, accurate, and precise analytical methods are needed …


Edible Mushrooms: An Emerging Therapeutic Of Diabetes, Nilanjan Chakraborty, Anuron Banerjee, Sudeshna Nandi, Swagata Sarkar, Krishnendu Acharya Aug 2022

Edible Mushrooms: An Emerging Therapeutic Of Diabetes, Nilanjan Chakraborty, Anuron Banerjee, Sudeshna Nandi, Swagata Sarkar, Krishnendu Acharya

The Thai Journal of Pharmaceutical Sciences

Diabetes is the third most customary non-infectious disease occurring worldwide and leads to untimely disability and mortality. This metabolic disorder is characterized by impaired insulin secretions and high blood glucose levels. Among others, type 2 diabetes is the most common. Various chemical and biochemical hypoglycemic drugs are utilized to control and treat hyperglycemia but required further interventions to reduce their toxicity and side effects on the users. Edible mushrooms have been employed from ancient times to heal many diseases as it composed of anti-oxidant, alkaloids, fibers, triterpenoids, and other phytochemicals. The bioactive secondary metabolites of mushrooms can improve insulin resistance …


Determination Of Sugars And Amino Acids In Japanese Wine Using Core–Shell Liquid Chromatography Tandem Electrochemical Detection, Kana Yoshimura, Aiko Sano, Ryuichiro Suzuki, Shun-Ichi Mitomo, Yukiko Negishi, Toshiki Mutai, Florencio Arce Jr, Gerard Lee See, Takashi Tanikawa, Yutaka Inoue Aug 2022

Determination Of Sugars And Amino Acids In Japanese Wine Using Core–Shell Liquid Chromatography Tandem Electrochemical Detection, Kana Yoshimura, Aiko Sano, Ryuichiro Suzuki, Shun-Ichi Mitomo, Yukiko Negishi, Toshiki Mutai, Florencio Arce Jr, Gerard Lee See, Takashi Tanikawa, Yutaka Inoue

The Thai Journal of Pharmaceutical Sciences

In this study, sugars (glucose, fructose, and sucrose) and amino acids in plum and yuzu wines were quantified with a new and simple method involving an electrochemical detector (ECD) and core–shell column (S-30/70 = Styrene/divinylbenzene – 5 tetramethyldiaminohexane). Analysis was conducted under the following conditions: A column temperature (40°C), flow rate (0.3 mL/min), injection volume (20 μL), and mobile phase (0.1 mol/L NaOH). Glucose, fructose, and sucrose had retention times of 14.68 min, 16.22 min, and 19.29 min, respectively, when measured using an ECD. When the sugar content was compared among the plum wines, plum wine A had the lowest …


Hemogram Results And Renal Function Before And After Administration Of Black Cumin Seed Oil In Healthy Volunteers, Titiek Hidayati, Akrom Akrom, Sagiran Sagiran, Indrayanti Indrayanti Aug 2022

Hemogram Results And Renal Function Before And After Administration Of Black Cumin Seed Oil In Healthy Volunteers, Titiek Hidayati, Akrom Akrom, Sagiran Sagiran, Indrayanti Indrayanti

The Thai Journal of Pharmaceutical Sciences

No abstract provided.


Formulation, Characterization, And Pharmacokinetic Study Of Methoteraxate-Quercetin Loaded Nanoparticles, Gyanesh Kumar Sahu, Harish Sharma, Swarnali Das Paul, Ajazuddin, Chanchal Deep Kaur Aug 2022

Formulation, Characterization, And Pharmacokinetic Study Of Methoteraxate-Quercetin Loaded Nanoparticles, Gyanesh Kumar Sahu, Harish Sharma, Swarnali Das Paul, Ajazuddin, Chanchal Deep Kaur

The Thai Journal of Pharmaceutical Sciences

Objectives: Methotrexate (MTX) is a biopharmaceutics classification system Class IV drug having potential cytotoxic action against cancer cells. However, short half-life and poor bioavailability have limited its application. The object of this work was to entrap MTX and an herbal bioenhancer in a nanoparticle system to improve its bioavailability. Methods: We prepared the nanoparticles (NPs) by emulsion solvent evaporation method with Eudragit RLPO (ERLPO) polymer. Results: The result revealed good in vitro properties with 110 to 228 nm particle size range. The percentage of drugs released from all the batches in 72 h was within the range of 82.71 to …


Marital Satisfaction In Patients With Breast Cancer Who Have Undergone Mastectomy At King Chulalongkorn Memorial Hospital, Chatchadaporn Pornleegalearn, Chutima Roomruangwong Jul 2022

Marital Satisfaction In Patients With Breast Cancer Who Have Undergone Mastectomy At King Chulalongkorn Memorial Hospital, Chatchadaporn Pornleegalearn, Chutima Roomruangwong

Chulalongkorn Medical Journal

Background: Breast is an organ that affects sexual symbol and sexual satisfaction. The patients with mastectomy may suffer from both physical and psychological effects. The reaction from their close relatives can lead negative effects to the patients, especially, in term of body image. Previous studies in Thailand focused on depression, body image, coping style, and quality of life in breast cancer patients who had undergone mastectomy. However, there are few studies on marital satisfaction and sexual satisfaction. Objectives: To investigate marital satisfaction and related factors in breast cancer patients who had undergone mastectomy at King Chulalongkorn Memorial Hospital. Methods: A …


Surgical Perspectives Of Primary Liver Tumors In Children: A Series Of 76 Consecutive Cases, Pailin Arunsopha, Kanokrat Thaiwatcharamas, Sinobol Chusilp, Patchareeporn Tanming, Pongserath Sirichindakul, Nimmita Srisan, Katawaetee Decharun, Soottiporn Chittmittrapap, Paisarn Vejchapipat Jul 2022

Surgical Perspectives Of Primary Liver Tumors In Children: A Series Of 76 Consecutive Cases, Pailin Arunsopha, Kanokrat Thaiwatcharamas, Sinobol Chusilp, Patchareeporn Tanming, Pongserath Sirichindakul, Nimmita Srisan, Katawaetee Decharun, Soottiporn Chittmittrapap, Paisarn Vejchapipat

Chulalongkorn Medical Journal

Background: Primary liver tumors in children are rare. The objective of this study was to review cases of primary liver tumors in children who underwent tumor removal. Methods: Children (0 - 15 years old) who underwent surgery for primary liver tumors between 2006 and 2019 were studied. Their clinical data and pathological reports were reviewed. Demographic data, types of procedures, operative time, and post-operative complications were described. Data are expressed as mean  standard deviation. Results: There were 76 children (male/female = 39/37), who underwent resection for primary liver tumors. Their average age was 27.9  32.0 months. Asymptomatic abdominal …


Antioxidative Properties Of Common Ready-To-Eat Cooked Foods And Beverages In Thailand, Kamonchanok Chuenwisad, Nattida Chotechuang, Chanchai Boonla Jul 2022

Antioxidative Properties Of Common Ready-To-Eat Cooked Foods And Beverages In Thailand, Kamonchanok Chuenwisad, Nattida Chotechuang, Chanchai Boonla

Chulalongkorn Medical Journal

Background: Increased dietary antioxidant consumption is associated with decreased risk of oxidative stressmediated diseases. Cooking process affects the quantity and quality of antioxidants in foods. In this study, we investigated the antioxidative properties of ready-to-eat (RTE) cooked meals. Objective: To determine the total antioxidant capacity (TAC), total phenolic content (TPC), and total flavonoid content (TFC) in RTE cooked foods and beverages commonly sold in Thailand. Methods: Thirty cooked food items were purchased from local fresh markets and canteens in Bangkok. The foods were categorized into Central food, Northern food, Northeastern food, Southern food, fast food, and beverage. Levels of TAC …


Self-Objectification, Eating Disorders, And Mental Health Of Senior High School Female Students In Bangkok, Gunchanon Khawda, Siriluck Suppapitiporn Jul 2022

Self-Objectification, Eating Disorders, And Mental Health Of Senior High School Female Students In Bangkok, Gunchanon Khawda, Siriluck Suppapitiporn

Chulalongkorn Medical Journal

Background: High school female students have higher self-objectification more than others. Many studies showed that self-objectification was positively correlated with eating disorders and negative mental health outcomes. Objectives: To study relationships among self-objectification, eating disorders, and mental health of senior high school female students in Bangkok and to study predictors of eating disorders. Methods: The cross-sectional descriptive study was conducted in high school female students who was studying in Mathayom 6th from 6 schools in Bangkok. The data were collected by questionnaires including demographic data questionnaire, self-objectification questionnaire, the Eating Attitudes Test-26 in Thai version (EAT-26), and Thai Mental Health …