Digital Commons Network^™

Passive RGe Or Developmental Gene-Environment Cascade? An Investigation Of The Role Of Xenobiotic Metabolism Genes In The Association Between Smoke Exposure During Pregnancy And Child Birth Weight, Kristine Marceau, Rohan H.C. Palmer, Jenae M. Neiderhiser, Taylor F. Smith, John E. Mcgeary, Valerie S. Knopik

Psychology and Child Development

There is considerable evidence that smoke exposure during pregnancy (SDP) environmentally influences birth weight after controlling for genetic influences and maternal characteristics. However, maternal smoking during pregnancy—the behavior that leads to smoke exposure during pregnancy—is also genetically-influenced, indicating the potential role of passive gene-environment correlation. An alternative to passive gene-SDP correlation is a cascading effect whereby maternal and child genetic influences are causally linked to prenatal exposures, which then have an ‘environmental’ effect on the development of the child’s biology and behavior. We describe and demonstrate a conceptual framework for disentangling passive rGE from this cascading GE effect using …

Executive Committee - Meeting Minutes, 1/5/2016, Academic Senate

Academic Senate Minutes

No abstract provided.

Executive Committee - Agenda, 1/5/2016, Academic Senate

Academic Senate Agendas

No abstract provided.

Growth Rate Of Copepods In The San Francisco Bay, Brooke Bemowski, Wim Kimmerer, Toni Ignoffo

STAR Program Research Presentations

The San Francisco Estuary is a complex ecosystem. A key part of the foodweb are zooplankton crustaceans, specifically copepods. Many fish, especially the endangered delta smelt, rely on copepods as a food source. Measuring the growth of copepods assists in predictions if enough food is available for delta smelt. Traditionally growth rate is measured through lengthy and involved processes. The objective of this research project is to develop an imaging process to analyze biomass of copepods more efficiently. For this research, field samples of copepods were collected and grown over three days. Subsamples were taken and preserved at three predetermined …

Understanding Molecular Bonding In Vitamin B12 Using X-Ray Spectroscopy, Jamie N. Lehnen

STAR Program Research Presentations

It is often difficult to accurately describe the electronic configuration of large molecules like cobalamin (Vitamin B12). By defining the electronic and geometric structure of a molecule using X-ray spectroscopy, we can better understand how that molecule behaves. Cobalamin is a molecule of interest because it typically displays dehalogenating properties in the body. By understanding more of how cobalamin analogues operate, it becomes possible to know their chemical properties and reactions.

2015/2016 Robert E. Kennedy Library Annual Report, Robert E. Kennedy Library

Library Publications and Administrative Reports

In 2015-16, $500,000 in student success fees to the library that allowed us to move forward with some exceptional building transformations. Read about these and other highlights in the 2015-16 report.

Giovanni Battista Palumba's Mythological Progeny, Giancarlo Fiorenza

Art and Design

No abstract provided.

Automated Detection And Analysis Of Depolarization Events In Human Cardiomyocytes Using Madec, Agnieszka F. Szymanska, Christopher M. Heylman, Rupsa Datta, Enrico Gratton

Biomedical Engineering

Optical imaging-based methods for assessing the membrane electrophysiology of in vitro human cardiac cells allow for non-invasive temporal assessment of the effect of drugs and other stimuli. Automated methods for detecting and analyzing the depolarization events (DEs) in image-based data allow quantitative assessment of these different treatments. In this study, we use 2-photon microscopy of fluorescent voltage-sensitive dyes (VSDs) to capture the membrane voltage of actively beating human induced pluripotent stem cell-derived cardiomyocytes (hiPS-CMs). We built a custom and freely available Matlab software, called MaDEC, to detect, quantify, and compare DEs of hiPS-CMs treated with the β-adrenergic drugs, propranolol and …

Label-Free Imaging Of Metabolism And Oxidative Stress In Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes, Rupsa Datta, Christopher M. Heylman, Steven C. George, Enrico Gratton

Biomedical Engineering

In this work we demonstrate a label-free optical imaging technique to assess metabolic status and oxidative stress in human induced pluripotent stem cell-derived cardiomyocytes by two-photon fluorescence lifetime imaging of endogenous fluorophores. Our results show the sensitivity of this method to detect shifts in metabolism and oxidative stress in the cardiomyocytes upon pathological stimuli of hypoxia and cardiotoxic drugs. This non-invasive imaging technique could prove beneficial for drug development and screening, especially for in vitro cardiac models created from stem cell-derived cardiomyocytes and to study the pathogenesis of cardiac diseases and therapy.

Designing And Creating A Website: "Low-Stress Handling Beef Cattle", Lauren Rothstein

Agricultural Education and Communication

No abstract provided.

Density-Based Clustering Of High-Dimensional Dna Fingerprints For Library-Dependent Microbial Source Tracking, Eric Johnson

Master's Theses

As part of an ongoing multidisciplinary effort at California Polytechnic State University, biologists and computer scientists have developed a new Library-Dependent Microbial Source Tracking method for identifying the host animals causing fecal contamination in local water sources. The Cal Poly Library of Pyroprints (CPLOP) is a database which stores E. coli representations of fecal samples from known hosts acquired from a novel method developed by the biologists called Pyroprinting. The research group considers E. coli samples whose Pyroprints match above a certain threshold to be part of the same bacterial strain. If an environmental sample from an unknown host animal …

Gopher Intrusion In Cropping Systems, Kenneth Romero, Paul Cardinalli

Agricultural Education and Communication

The purpose of this project was to determine if no till vs. till on gopher populations was more beneficial. Which is more efficient at controlling gophers and explain the damage they can cause and the diseases they can potentially vector. What are the different options of pest managements that have to be used when dealing with a gopher infestation in a tilled field vs. a no-tilled field.

Resource Partitioning Along Multiple Niche Axes Drives Functional Diversity In Parrotfishes On Caribbean Coral Reefs, Thomas C. Adam, Megan Kelley, Benjamin I. Ruttenberg, Deron E. Burkepile

Biological Sciences

The recent loss of key consumers to exploitation and habitat degradation has significantly altered community dynamics and ecosystem function across many ecosystems worldwide. Predicting the impacts of consumer losses requires knowing the level of functional diversity that exists within a consumer assemblage. In this study, we document functional diversity among nine species of parrotfishes on Caribbean coral reefs. Parrotfishes are key herbivores that facilitate the maintenance and recovery of coral-dominated reefs by controlling algae and provisioning space for the recruitment of corals. We observed large functional differences among two genera of parrotfishes that were driven by differences in diet. Fishes …

Native Deer Mice (Peromyscus Maniculatus) Use Of Invasive Grass Seed (Ehrharta Calycina) In Coastal California, Megan Wong

Biological Sciences

No abstract provided.

Una Legua Cuadrada: Exploring The History Of Swanton Pacific Ranch And Environs, Jeanine Marie Scaramozzino

Master's Theses

Swanton Pacific Ranch is an educational and research facility owned by the Cal Poly Corporation and managed by the Cal Poly State University (Cal Poly) College of Agriculture, Food and Environmental Sciences. Located about 180 miles north of campus and just 14 miles north of Santa Cruz, California on Highway 1, the property was first leased to and then donated to Cal Poly by the late Albert E. Smith in 1993. The rancho’s original inhabitants included Native Americans, Spaniards, Mexicans, as well as various European immigrants and their descendants; currently, the staff, faculty, and students of Cal Poly occupy the …

Graduate Internship In Agriculture Education - Central Valley High School, Jessica Lynne Cardoso

Agricultural Education: Graduate Internship Reports

An in depth evaluation of the agriculture program for Central Valley High School in Ceres, CA

Midfield Rf Signal Detector, Dawei Zhang

Electrical Engineering

This project is part of a Master’s thesis which looks at alternative ways to measure blood glucose. The Master’s thesis uses mid-field signals in order to match impedance and therefore lose less power as they travel through flesh. The goal of this senior project is to build a receiver for those signals and give accurate RSSI (received signal strength indicator) measurements. Mid-fields were originally explored by Stanford professor Dr. Ada Poon [3] who used the signaling technique to recharge the batteries of deeply implanted devices. Devices implanted near the surface of the skin were able to have their batteries recharged …

Medical Image Registration Using Artificial Neural Network, Hyunjong Choi

Master's Theses

Image registration is the transformation of different sets of images into one coordinate system in order to align and overlay multiple images. Image registration is used in many fields such as medical imaging, remote sensing, and computer vision. It is very important in medical research, where multiple images are acquired from different sensors at various points in time. This allows doctors to monitor the effects of treatments on patients in a certain region of interest over time. In this thesis, artificial neural networks with curvelet keypoints are used to estimate the parameters of registration. Simulations show that the curvelet keypoints …

As-809-15 Resolution On Action To Promote Timely Completion Of The Graduate Writing Requirement, Academic Senate Executive Committee

Academic Senate Resolutions

Approval of report and implementation of recommendations to improve the GWR process

Academic Senate - Agenda, 12/1/2015, Academic Senate

Academic Senate Agendas

No abstract provided.

Marketing Alaskan Seafood: Strategies With Brand Identification, Differentiation, And Promotions, Anna Jacobson

Journalism

Everyday the globe experiences changes with food. New methods in growing and harvesting are becoming approved, while others are frowned upon. People care more about where their food comes from than ever before. This research is to explore how Alaska seafood can successfully market their products in an ever-changing world. As challenges present themselves in the industry, opportunities are there as well.

This study sets out to explore marketing strategies for promoting a seafood brand. Through exploring current literature and interviewing experts to obtain data, conclusions will be drawn and analyzed. These findings will help to understand the best practices …

Master's Of Agriculture Education, Katrina Marie Chamberlin

Agricultural Education: Graduate Internship Reports

This internship/project report includes validation documents required in meeting the quality criteria for secondary- level programs of instruction in agriculture. The documents are concurrently used for the Agriculture Incentive Grant review process at Independence High School conducted by representatives of the California Department of Education. The internship included the development of a chapter website to provide information and publicity for the Independence FFA Chapter. It serves as a repository of chapter information and documents, a home for current information, and as a public face for the chapter. The project also includes the development of an Advisory Committee for Independence High …

The Effects Of Foliar Nutrient Applications On Split, Yield, And Internal Fruit Quality Of 'Wonderful' Pomegranate (Punica Granatum L.), John Matthew Chater

Master's Theses

Fruit split is the most important physiological disorder in pomegranate production, causing devastating crop losses worldwide. Foliar nutrient applications have been used experimentally to mitigate pomegranate fruit split but none have been conducted using the industry standard cultivar, Wonderful, and little is known about the effects of foliar nutrient applications on pomegranate. Additionally, investigations into putative health benefits of pomegranate fruit have increased interest in its production but limited evidence exists regarding effects of agricultural practices such as foliar fertilizer applications on internal fruit quality. ‘Wonderful’ pomegranate trees at 2 commercial orchards were treated with foliar applications of ZnSO_{4 …}

Production And Harvest Of Microalgae In Wastewater Raceways With Resource Recycling, Alexander Colin Roberts

Master's Theses

Microalgae can be grown on municipal wastewater media to both treat the wastewater and produce feedstock for algae biofuel production. However the reliability of treatment must be demonstrated, as well as high areal algae productivity on recycled wastewater media and efficient sedimentation harvesting. This processes was studied at pilot scale in the present research.

A pilot facility was operated with nine CO₂-supplemented raceway ponds, each with a 33-m² surface area and a 0.3-m depth, continuously from March 6, 2013 through September 24, 2014. The ponds were operated as three sets of triplicates with two sets continuously fed …

Structural Damage Assessment Using Artificial Neural Networks And Artificial Immune Systems, Arthur Q.X. Shi

Master's Theses

Structural health monitoring (SHM) systems have been technologically advancing over the past few years. Improvements in fabrication and microelectronics allow the development of highly sophisticated sensor arrays, capable of detecting and transmitting an unprecedented amount of data. As the complexity of the hardware increases, research has been performed in developing the means to best utilize and effectively process the data. Algorithms from other computational fields are being introduced for the first time into SHM systems. Among them, the artificial neural network (ANN) and artificial immune systems (AIS) show great potential. In this thesis, features are extracted out of the acceleration …

Spacecraft Trajectory Optimization Suite (Stops): Optimization Of Multiple Gravity Assist Spacecraft Trajectories Using Modern Optimization Techniques, Timothy J. Fitzgerald

Master's Theses

In trajectory optimization, a common objective is to minimize propellant mass via multiple gravity assist maneuvers (MGAs). Some computer programs have been developed to analyze MGA trajectories. One of these programs, Parallel Global Multiobjective Optimization (PaGMO), uses an interesting technique known as the Island Model Paradigm. This work provides the community with a MATLAB optimizer, STOpS, that utilizes this same Island Model Paradigm with five different optimization algorithms. STOpS allows optimization of a weighted combination of many parameters. This work contains a study on optimization algorithm performance and how each algorithm is affected by its available settings.

STOpS successfully found …

Identifying And Predicting Rat Behavior Using Neural Networks, Jonathan A. Gettner

Master's Theses

The hippocampus is known to play a critical role in episodic memory function. Understanding the relation between electrophysiological activity in a rat hippocampus and rat behavior may be helpful in studying pathological diseases that corrupt electrical signaling in the hippocampus, such as Parkinson’s and Alzheimer’s. Additionally, having a method to interpret rat behaviors from neural activity may help in understanding the dynamics of rat neural activity that are associated with certain identified behaviors.

In this thesis, neural networks are used as a black-box model to map electrophysiological data, representative of an ensemble of neurons in the hippocampus, to a T-maze, …

Two-Phase Anaerobic Digestion To Reduce The Nox Emission Potential Of Biogas, Nathaniel Manuel Olivas

Master's Theses

Anaerobic digestion can be used to decrease the mass of organic wastes to be disposed of while producing useful biogas (CH₄ and CO₂) for heat or power production, but in air basins with strict emissions limits, biogas combustion is difficult to implement due to the high costs of controlling NOx emissions. NOx production can be minimized by blending H₂ gas with CH₄ at a volume ratio of 15:85 H₂:CH₄, which allows burning at ultra-lean air-to-fuel ratios. For biogas systems, a potential low-cost NOx control strategy is to produce H₂-CH …

Predicting Invasive Range Of Eucalyptus Globulus In California, Anthony J. Lopez

Master's Theses

Eucalyptus globulus is the subject of intense debate in California. Its invasive potential, aggressive growth, reproductive biology, and association with fire make the prediction of spread important in California. Two modeling simulations, Climex and Maxent, will illustrate the distribution and potential growth range of E. globulus in California based on climate and presence. Modeling the potential range of growth will predict invasive spread. The anticipated result is the continued spread of E. globulus in coastal regions with adequate moisture and suitable climate. Predicting the range of E. globulus in California dictates management strategy and is key for preventing further introduction, …

Rights, Solidarity, And The Animal Welfare State, Jes L. Harfeld

Between the Species

This article argues that aspects of the animal rights view can be constructively modulated through a communitarian approach and come to promote animal welfare through the social contexts of expanded caring communities. The Nordic welfare state is presented as a conceivable caring community within which animals could be viewed and treated appropriately as co-citizens with solidarity based rights and duties.