Digital Commons Network^™

Effect Of Prolonged Probiotic Supplementation In A High-Fructose Diet In A Pig Model Of Non-Alcoholic Fatty Liver Disease, Victoria Smith, Meghan Melnyk

Baker/Koob Endowments Awarded Projects

Non-alcoholic fatty liver disease (NAFLD) is the leading cause of pediatric chronic liver condition, caused by hepatic inflammation, insulin resistance and steatosis. We hypothesize that prolonged intake of diets rich in carbohydrates, specifically fructose, will induce NAFLD in infants, whereas probiotics may ameliorate the symptoms of the disease. To assess the effect of dietary fructose and probiotics in the pathology of the disease, 24 leptin resistant neonate pigs will be assigned to 1 of 4 treatment diets for 10 weeks: 1) control (CON), 2) high fructose (HF), 3) CON + probiotics, 4) HF + probiotics. Animals will be fed 40 …

Rethink Infrastructure, Khoa Le, Arielle Eleazar

Goals

In the Camp Fire, Paradise lost thousands of houses as well as stores, gas stations, and many other private commercial enterprises. But the town also lost many significant civic institutions. The projects on this poster show some of the individual projects intended to replace those institutions. These are ones that could provide renewed focus towards the community’s wellness, sustainability, governance, and education.

Paradise W.E.T. Center, Arielle Eleazar

Studio Projects

Arielle Eleazar’s Paradise W.E.T. Center is a project focused on water education and actual treatment, located just below the proposed East Village downtown. The goal of this center is to provide an alternative solution to the town’s wastewater management by showcasing a hybrid system heavily reliant on biological filtration. This building also serves as a live demonstration area for water conservation, educating the public about the importance of water as a resource.

Analyzing The Hypervolume Of Plant Functional Traits In The Sierra Nevada Mountain Range, Rosina Garcia, David Schimel, Ryan Pavlick

STAR Program Research Presentations

Studying Earth’s biodiversity is important in understanding how ecosystems are changing in response to environmental stressors. Particularly, monitoring Earth via remote sensing can give us high-resolution data of plant functional traits, such as canopy height, leaf mass per area (LMA), and leaf nitrogen content, which provide insight into ecosystem changes. We mapped out remote sensing airborne data from the Sierra Nevada Mountain Range in California and used R to create a hypervolume of the vegetated area. Hypervolumes are useful in creating a three-dimensional visualization of data to understand the relationships among different traits. We computed the three-dimensional space of the …

Survival And Growth In Experimental Plots At A Santa Rosa Island Restoration Site, 2016-2018, Marisol Gonzalez Villarreal, Robyn Shea, Aspen Coty

STAR Program Research Presentations

Survival and Growth in Experimental Plots at a Santa Rosa Island Restoration Site, 2016-2018 Marisol Villarreal1, Stephen Bednar2, Kathryn McEachern3 1Woodland Joint Unified School District, 2Mountains Restoration Trust, 3United States Geological Survey Restoration biology, the practice of healing a damaged landscape to that of a functioning ecosysytem, is as variable a science as they come. Restoration treatments may take into account precipitation, symbiotic relationships, microclimate, degree of plant succession, and soil conditions. The most effective restoration is based on experimental research. Such is the goal for the Cloud Forest Restoration Project on Santa Rosa Island, within Channel Islands National Park …

Method Development For Structural Assessment Of Nanolipoprotein Particles With And Without Cross-Linked Lipids, Emma J. Mullen, Wei He, Sean Gilmore, Matthias Frank, Matthew Coleman, Megan Shelby

STAR Program Research Presentations

Membrane proteins make up approximately 30% of the cellular proteome and account for over 60% of pharmaceutical targets.1 Determining the structures of this class of proteins is critical to our understanding of disease states and will advance rational drug design. But membrane proteins have limited solubility, rarely form large crystals that diffract well, and often misfold outside of a bilayer, hindering crystallographic studies.1 Nanolipoprotein particles (NLPs) have arisen as a platform to readily solubilize membrane proteins while mimicking a native lipid environment. NLPs consist of a discoidal phospholipid bilayer encircled by an apolipoprotein belt. In an effort to optimize and …

Comparing Regional Population Genetic Effects In Leptasterias Spp., Kristen N. Runge, Sarah Cohen

STAR Program Research Presentations

Leptasterias spp. is a species complex of six-rayed intertidal sea stars found along the northeast Pacific coast. A developmental mode of brooding their young, rather than broadcasting for planktonic development, limits dispersal away from the natal area, and may also result in local adaptation of populations. Local adaptation may lead to morphological and behavioral differences among populations. Previous studies on behavior in Leptasterias spp. have shown that activity levels may vary by population and region. Across three regions from California to Washington, differences were only observed between central California and more northern regions while northern California, Oregon, and Washington were …

2018/2019 Robert E. Kennedy Library Annual Report, Robert E. Kennedy Library

Library Publications and Administrative Reports

We have named our annual report Inside 35, and we are introducing a new format that aims to illustrate the impact of our programs on the Cal Poly community and how a library experience can transform lives and define future careers. The library, through all it has to offer, inspires and celebrates every student’s experience of learning, discovery and personal growth.

Paradise Museum Of The Natural World, Emma Puryear

Studio Projects

Emma Puryear’s Museum of the Natural World seeks to create a familiar project, both aesthetically and content-wise, that reconnects residents with the natural world. Located between the East and West Villages, it will be a place for everyone in the community as a cultural center that seeks to promote responsible environmentalism. The project seeks also to revitalize Paradise Park by incorporating an outdoor eco-exhibit and community garden.

Long-Term Phytoremediating Abilities Of Dalbergia Sissoo Roxb. (Fabaceae), Saqib Ul Kalam, Fauzia Naushin, Fareed Ahmad Khan, Nishanta Rajakaruna

Biological Sciences

The boom of tanneries in north India has converted the river Ganga into a waste dumping stream. The tanneries discharge their heavy metal-rich effluents into the river. Tissues of two-year-old tree saplings of Dalbergia sissoo, soil sediments and river water samples were collected from three sites along the river Ganga at Jajmau, Kanpur. Site-1 was located 1 km upstream from the point of discharge of the effluents of the tanneries, Site-2 was close to the source point, and Site-3 was about 1 km downstream from the source point. Accumulation of Cu, Cr and Ni in leaves, bark, wood growth rings, …

California Livestock Owners: An Assessment Of Familiarity With New Antimicrobial Rules And Access To Educational Outreach, Philip Theodor Paulson

Master's Theses

The purpose of this research is to support the California Department of Food & Agriculture (CDFA) with education and outreach about recent changes regarding antimicrobial use in livestock, and to enhance their emergency communications network. This was done by characterizing a population of small-scale livestock owners underserved with regards to educational outreach about animal health issues, such as antimicrobial use rules. The project also seeks to enhance public understanding of the importance of responsible antimicrobial use in animal and human health.

To accomplish this, the study used a survey administered in person at local farm supply stores and online to …

Surf Leg, Samantha Campbell, Oyundari Altansukh, Caroline Swanson, Kurtis Barth

Mechanical Engineering

The Surf Leg Prosthetic project team in conjunction with QL+ and Operation Surf designed a transtibial prosthetic to be used for surfing. The senior project team focused on the missions of QL+ and Operation Surf as they went through the design process during the 2018-2019 academic year. The problem solved was that a standard prosthetic for a transtibial amputee does not provide the flexibility in enough degrees of freedom for a user to squat and balance on a surfboard. The goal of this project was to create a device specifically designed to improve the user’s balance and control while surfing. …

Enhancing Group Social Perceptiveness Through A Swarm-Based Decision-Making Platform, David A. Askay, Lynn E. Metcalf, Louis Rosenberg, Gregg Willcox

Industrial Technology and Packaging

Swarm Intelligence is natural phenomenon that enables social animals to make group decisions in real-time systems. This process has been deeply studied in fish schools, bird flocks, and bee swarms, where collective intelligence has been observed to emerge. The present paper describes swarm.ai—a collaborative technology that enables swarms of humans to collectively converge upon a decision as a real-time system. Then we present the results of a study investigating if groups working as “human swarms” can amplify their social perceptiveness, a key predictor of collective intelligence. Results showed that groups reduced their social perceptiveness errors by more than half when …

Measuring Group Personality With Swarm Ai, Gregg Willcox, David Askay, Louis Rosenberg, Lynn Metcalf, Bryan Kwong, Richard Liu

Industrial Technology and Packaging

The aggregation of individual personality tests to predict team performance is widely accepted in management theory but has significant limitations: the isolated nature of individual personality surveys fails to capture much of the team dynamics that drive real-world team performance. Artificial Swarm Intelligence (ASI), a technology that enables networked teams to think together in real-time and answer questions as a unified system, promises a solution to these limitations by enabling teams to take personality tests together and converge upon answers that best represent the group’s disposition. In the present study, the group personality of 94 small teams was assessed by …

Predictors Of Resilience Among Infants At Risk For Rapid Weight Gain, Alison K. Ventura, Kristen Thompson

Kinesiology and Public Health

Objective: The study objective was to investigate factors associated with resilience to rapid weight gain (RWG) among predominantly bottle-fed infants.

Methods: Data came from 1,353 mothers who participated in the Infant Feeding Practices Study 2. Mothers completed a prenatal questionnaire and monthly surveys of infant feeding and growth between birth and 12 months. Infants were classified as resilient if they were predominantly bottle fed but did not exhibit RWG between birth and the latter half of infancy (≥ +0.67 change in weight-for-age z score).

Results: Thirty-five percent of the sample (n = 467) was predominantly bottle fed but did …

Validation Of The Nonhydrostatic General Curvilinear Coastal Ocean Mode (Gccom) For Stratified Flows, Mariangel Garcia, Paul Choboter, Ryan K. Walter, Jose E. Castillo

Physics

While global-and basin-scale processes can be captured quite well with computationally-inexpensive hydrostatic models, smaller-scale features such as shoaling nonlinear internal waves and bores, coastal fronts, and other convective processes require the use of a nonhydrostatic model to accurately capture dynamics. Here the nonhydrostatic capabilities of the General Curvilinear Coastal Ocean Model (GCCOM) in a stratified environment are introduced. GCCOM is a three-dimensional, nonhydrostatic Large Eddy Simulation (LES), rigid lid model that has the ability to run in a fully three-dimensional general curvilinear coordinate system. This model was previously validated for unstratified flows with curvilinear coordinates. Here, recent advances of the …

Academic Senate - Agenda, 12/04/2018, Academic Senate

Academic Senate Agendas

No abstract provided.

Radio Frequency Identification In The Beef Cattle Production Cycle At Livestock Services Inc., Edwin Mendoza

Agricultural Education and Communication

As time and technology has progressed, precision tracking has led many in the livestock industry to look into the next type of technology available to make their operations more efficient. This technology allows producers to individually track animals, with information ranging from weight, vaccinations used and pasture movements throughout the whole production cycle.

Applying Radio Frequency Identification (RFID) technology early in the production cycle can show that there is a higher accuracy in traceability that will decrease losses, and incorporate a better management style (Nääs, 2006).

Although this technology is in the initial testing stages in the multiple variations it …

Entrepreneur`S Guide To Starting A Rabbit Agricultural Enterprise, Mary Maldonado

Agricultural Education and Communication

At San Luis Obispo, the University Cal Ploy has an Animal Science Department that offers over twenty enterprises pertaining to livestock production which “provide the environment for students to get outside the classroom and work with the animals in teams of students” (Cal Poly 2017-19). As reported from the “Animal Science Department Enterprise Class List”, the classes involved help develop technical skills by having students learn and work in active production settings with livestock such as cows, steers, pigs, lambs, goats, and chickens (Animal Science Department 2017-19). However, when compared to the livestock accounted for at a traditional county fair …

Graduate Internship Report- Maxwell High School, Amber Charter

Agricultural Education: Graduate Internship Reports

This internship and project report includes documentation required in meeting the quality criteria for secondary-level programs of instruction in agriculture. The documents are concurrently used for the Agriculture Incentive Grant review process at Maxwell High School conducted by representatives of the California Department of Education. The supporting material includes information to receive state and local funding, outline the goals and objectives of the program, along with an overview of Maxwell High School, the agriculture program and the community.

Art Brut & Bricolage: Manifesting Alternate Imaginaries Of The Waste Cataclysm, Dominic Alan Chequer

Communication Studies

Living within a consumer society that boasts increased sustainable consumption as the panacea to large-scale environmental degradation, the social avoidance of waste becomes an interesting psychological battleground in developing an environmentally sustainable future. In light of this situation, I used my participation in the design of a music festival to create a social critique by design. Using artistic techniques of bricolage and aesthetic upcycling, under the visage of art brut. The paper blends theory and practice, ideas with tangible outputs.

Engineering Yeast To Evaluate Human Proteins Involved In Selective Rna Packaging During Hiv Particle Production, Ryan M. Bitter

Master's Theses

Despite recent advances in antiretroviral therapy, nearly 37 million people continue to live with human immunodeficiency virus (HIV). Basic and applied research on the assembly of HIV could be enhanced by using a genetically tractable organism, such as yeast, rather than mammalian cells. While previous studies showed that expression of the HIV Gag polyprotein in Saccharomyces cerevisiae spheroplasts resulted in the production of virus-like particles (VLPs), many questions regarding the utility of yeast in HIV assembly remain uninvestigated. Here, we report use of S. cerevisiae for both the production of VLPs with selectively packaged RNA and to evaluate the human …

Presence Of Antibiotic Resistant Salmonella Spp. In Backyard Poultry And Their Environment, Nicole Land

Master's Theses

As keeping backyard poultry rises, human contact with zoonotic pathogens will increase. One such pathogen that backyard enthusiasts have exposure risks to is Salmonella spp. which may cause a potential public health threat due to its increasing multidrug resistancy. Salmonella spp. were present in 33 of 50 samples collected from 29 sites with backyard poultry coops in San Luis Obispo County during March to May in 2014. Two different Hardy-CHROME™ Salmonella Selective Media plates were used to culture and isolate positive samples of Salmonella spp.. Each positive isolate was tested for antimicrobial sensitivity to 6 standard antibiotics: Ampicillin, Bacitracin, …

Investigating The Effect Of An Upstream Spheroid On Tandem Hydrofoils, Joel Tynan Guerra

Master's Theses

This thesis documents a series of three dimensional unsteady Reynolds Averaged Navier-Stokes CFD simulations used to investigate the influence of an upstream prolate spheroid body on tandem pitching hydrofoils. The model is validated by performing separate CFD simulations on the body and pitching hydrofoils and comparing results to existing experimental data. The simulations were run for a range of Strouhal numbers (0.2-0.5) and phase differences (0-π). Results were compared to identical simulations without an upstream body to determine how the body affects thrust generation and the unsteady flow field.

The combined time-averaged thrust increases with Strouhal number, and is highest …

Amplifying The Prediction Of Team Performance Through Swarm Intelligence And Machine Learning, Erick Michael Harris

Master's Theses

Modern companies are increasingly relying on groups of individuals to reach organizational goals and objectives, however many organizations struggle to cultivate optimal teams that can maximize performance. Fortunately, existing research has established that group personality composition (GPC), across five dimensions of personality, is a promising indicator of team effectiveness. Additionally, recent advances in technology have enabled groups of humans to form real-time, closed-loop systems that are modeled after natural swarms, like flocks of birds and colonies of bees. These Artificial Swarm Intelligences (ASI) have been shown to amplify performance in a wide range of tasks, from forecasting financial markets to …

Case Study: Environmental Requirements And Its Impacts Upon The Conservation Center For Wildlife Care, Chase Flemmer

Construction Management

As the population of California continues to grow, urban spaces are rapidly being developed into areas considered to be environmentally sensitive. In order to prevent extensive damage to our state’s delicate ecosystems, environmental regulations are often enforced by local organizations during the course of impactful operations such as construction projects. These regulations will often vary from one site to another, depending on a given site’s location and proximity to the environmentally sensitive areas. No two jobs will posses the exact same specifications for dealing with this aspect of construction, and as such some will require more intense regulations than others. …

Noise Induced Hearing Loss Accountability On Jobsites Within The Construction Industry, Joseph O. Lamphere

Construction Management

Noise induced hearing loss is a major issue on jobsites within the construction industry. Every day workers are exposed to hazardous levels of noise, but they are not being properly managed to mitigate this issue. Workers have misconceptions about the topic, but more surprisingly are sometimes indifferent to the effects; believing hearing loss is inevitable, or it can be cured with a hearing aide. Construction has inherent dangers that workers have to deal with every day. Hearing loss might not be on the top of their lists, but the effects are permanent, and they cannot be cured with a hearing …

Using Offline Activities To Enhance Online Cybersecurity Education, Sarah Padlipsky

Master's Theses

Since the beginning of the 21st century, the United States has experienced the impact of a technological revolution. One effect of this technological revolution is the creation of entirely new careers related to the field of technology, including cybersecurity. Continued growth in the cybersecurity industry means a greater number of jobs will be created, adding to the existing number of jobs that are challenging an under-educated and under-trained workforce. The goal of this thesis is to increase the effectiveness of cybersecurity education. This thesis studies whether an online course in cybersecurity can be enhanced by offline, in-person activities that mirror …

Cold Acclimation Response Of Non-Native Italian Wall Lizard (Podarcis Siculus) Populations From New York And California, Daniel Haro

Master's Theses

Understanding how organisms respond to climatic variability and novel conditions is becoming an increasingly important task for ecologists. For ectotherms in the northern hemisphere, the response to cold is of special interest, considering that poleward range expansion events and increasing variability of temperatures during winter are already being observed as consequences of a warming planet. Though direction of change in physiological variables in response to cold is well studied in ectotherms, the extent to which traits can change and the rate at which they can change is not.

We compared the extent and rate of change in cold tolerance (CT …

Comparative Analysis Of Electrodynamic Toroidal Radiation Shielding Configurations, Max Rosenberg

Master's Theses

Beyond the protective confines of Earth's atmosphere and magnetosphere, spacecraft are subject to constant bombardment by high-energy charged particles originating from our Sun in the form of Solar Particle Events (SPEs), and from outside the solar system in the form of Galactic Cosmic Rays (GCRs). The harm these particles do can be reduced or mitigated outright through radiation shielding. Because protons and other charged particles comprise most of these radiation particles, strong magnetic fields could be generated around spacecraft to deflect incoming charged radiation particles. This thesis investigates the performance of specific configurations of toroidal superconducting solenoids to generate magnetic …