Digital Commons Network^™

Development Of A Prolyl Endopeptidase Expression System In Lactobacillus Reuteri To Reduce The Clinical Manifestation Of Celiac Disease, Kara Lynn Jew

Master's Theses

Celiac Disease (CD) is an autoimmune disorder that emerges due to the ingestion of gluten, a protein found in a variety of common grains such as wheat, rye, and barley. Approximately 1 in 100 individuals in the US suffer from CD, making it the most commonly diagnosed gastrointestinal disorder (Ciclitira et. al., 2005). These proline-rich gluten peptides are resistant to proteolysis and accumulate in the duodenum of the small intestine. Once in the duodenum, these peptides illicit an autoimmune response resulting in villous atrophy. Current treatment for CD requires a rigorous adherence to a gluten-free diet. Nevertheless, gluten-containing grains are …

Academic Senate - Agenda, 6/04/2019, Academic Senate

Academic Senate Agendas

No abstract provided.

Impact Of Probiotics On Gastrointestinal Pathogenic Growth And Host Tight Junction Integrity, Rachel Cohen

Baker/Koob Endowments Awarded Projects

Over the past decade, interest in the use of probiotics, or “good bacteria”, for human health advancement and remediation has grown. Previous studies have shown that some health benefits conferred by probiotics are strain specific, therefore individual probiotic effects must be evaluated. This study evaluated some probiotic candidates on their ability to produce metabolites which inhibit the growth of foodborne pathogens. Probiotics are known to inhibit growth of other bacteria through competitive exclusion and production of bactericidins. In addition, previous studies have established that some probiotics promote the integrity of tight junctions, proteins that play a role in intestinal epithelial …

Erosion Resistance Of Tungsten-Carbide Coatings For Steel Pipes In Fluid Catalytic Cracking Units, Davis Vannasing, Jennifer Hulfachor

Materials Engineering

In petroleum processing, the flow of catalyst readily leads to erosion of piping in a fluid catalytic cracking unit. Advances in coating materials and processes necessitate a re-evaluation of current protection methods. Commercially available tungsten-carbide (WC) claddings and nanostructured WC-W CVD coatings were investigated as potential alternative erosion-resistant coatings. Erosion tests by solid particle impingement were conducted on 2 variations of claddings and 1 variation of WC-W coatings following ASTM standard G76. A36 steel coupons were used as reference samples. For statistical validation, 2-3 replications of the tests were performed for the claddings and WC-W coating. Testing was conducted using …

Keylime, Matthew Orgill

Computer Engineering

This project creates an iOS mobile app geared specifically toward the students of California Polytechnic State University. The app aims to provide the ability for users to discover new restaurants to checkout in the central coast area. These restaurants can be filtered to the user’s choosing based on the price of food, rating the restaurant has received, distance away from the user, and type of food. In addition, featured deals that local restaurants currently offer can be found on the app. Each restaurant can be favorited by the user to allow for better filtering of discovering new restaurants and to …

Farming Forward, Karina Medrano

Agricultural Education and Communication

How can the next generation be inspired to be problem solvers and innovators in order to impact the global food system? With the large millennial generation it is as important as ever to develop new platforms to spread agricultural awareness and literacy. With the millennial generation being increasingly connected to technology and media platforms, understanding how to create a mainstreamed farming blog will be valuable in reaching the future generation of agriculturalists.

This project will develop a proposal for a farming blog platform and review essential elements to include within a blog ranging from an up to date news section …

Creation And Implementation Of Marketing Collateral For The Agricultural Education And Communication Department At California Polytechnic State University, San Luis Obispo, Bekah Marjorie Reed

Agricultural Education and Communication

In January, 2019 the author created a template in Adobe InDesign to input information to be gathered from professors. The intent of the template was to display relevant information to help students learn more about their future faculty: hometown, areas of research, industry/teaching experience, alma maters, among other information (email address, office location, and office phone number). The author then developed questions and emailed all of the faculty and staff in the Agricultural Education and Communication Department along with a request for a headshot from each member. For those who did not have a headshot available to them, or who …

The Wine Stone Inn, Kendall N. Doud

Agricultural Education and Communication

The Wine Stone Inn is a new 12-room boutique hotel currently being built in Old Town Orcutt, California. The hotel is seeking a grand opening that will attract vintner business, agribusiness, and agricultural vendors for the hotel, and help promote local wineries and breweries in the Santa Maria Valley. Orcutt is a growing township, which is becoming very attractive to visitors because of the walking distance to restaurants, local pubs, wine venues, and other businesses that project growth in the future. Agribusiness makes up a small percentage of the corporate market and agritourism is a growing segment in this area. …

Implementation Of Multivariate Artificial Neural Networks Coupled With Genetic Algorithms For The Multi-Objective Property Prediction And Optimization Of Emulsion Polymers, David Chisholm

Master's Theses

Machine learning has been gaining popularity over the past few decades as computers have become more advanced. On a fundamental level, machine learning consists of the use of computerized statistical methods to analyze data and discover trends that may not have been obvious or otherwise observable previously. These trends can then be used to make predictions on new data and explore entirely new design spaces. Methods vary from simple linear regression to highly complex neural networks, but the end goal is similar. The application of these methods to material property prediction and new material discovery has been of high interest …

The Lone Coyote Of The National Basketball Association: A Case Study On The Organization Culture Of The San Antonio Spurs, Dylan O. Staub

Experience Industry Management

Organizational culture exists within every professional sports team’s organization and makes up the organization’s DNA. The San Antonio Spurs are one such Professional Sports organization that innovates new global team building strategies that values the group as a whole over the individual. The purpose of this study was to examine the organizational culture of the San Antonio Spurs franchise in the National Basketball Association (NBA). The researcher used a best-practices guide to evaluate the San Antonio Spurs’ corporate culture. This study found that the San Antonio Spurs are effective in their organizational culture practices, however, could focus their efforts more …

Fowler Studio Albuquerque, New Mexico Rail Yards - 2019, Thomas Fowler, Iv

Architecture

No abstract provided.

At The Intersection Of Hope And Despair: Korea’S Uncertain Trajectory In The 1980s, Haley Noelle Cole

History

The 1980s in South Korea were defined by political factionalism and constant protest. The brief ecstasy afforded by the assassination of the dictatorial president Park Chung Hee in 1979 gave way to disillusionment with the policies of his successor, Chun Doo Hwan. Throughout Chun’s term, he sought to subvert popular perceptions of his authoritarian illegitimacy he earned through the bloody military coup with which he obtained power. Chun hoped to justify his presidency within the contexts of 1) the 1987 presidential election, wherein the country would witness its first peaceful transfer of power in the post-war era, and 2) the …

Consumer Choice Within Fresh Produce, Victoria C. Ross

Agricultural Education and Communication

This project set out to question whether fresh produce required more specific labeling of pesticides and fertilizer inputs on fresh produce. Like many questions regarding health, environmental science, agriculture, and politics, there is not one simple answer. After listening to professionals and interviewing customers outside grocery stores, it's clear that the majority of consumers are not pursuing additional information, but that there is a small group of customers who would appreciate it. It also became clear that although fear mentality is of concern to professionals in the food industry, consumers don’t seem to understand the negative effects their participation in …

Succession Planning In Farming- A Guided Step, Alexandra Lavy

Agricultural Education and Communication

The author began this project by researching a variety of tax laws, succession planning, and what document and resources were already available to farming and ranching families.

For example, for the Introduction to Succession Planning in California section, the author described what succession planning is and explained the process. The author explained that a study found that nearly 50% of farmers do not have a succession plan, and how not being prepared will affect those farmers. This project created a guideline for farmers to follow when planning their succession, as well as why it is important. This project outlined the …

Farmer And Rancher Suicide Prevention Posters, Kayla Dawn Copus

Agricultural Education and Communication

To develop a poster for farmer and rancher suicide awareness, the author first researched general suicide prevention and awareness posters to see analyze successful examples and to get ideas for potential themes, colors, and content. The ideas generated in this process needed to be methodically applied to make the content relevant and relatable for those in the agricultural industry. In this process, the author chose to incorporate a word cloud filled with words that represent agricultural issues and influence farmer and rancher suicide. The phrase “Suicide does not solve agricultural issues,” was chosen to use as the title at the …

Cal Poly State University Robert E. Kennedy Library Fire Protection Analysis Report, Timothy Anderson

Fire Protection Engineering: Culminating Experience Project Reports

This report determines whether or not the fire protection and life safety features of Robert E. Kennedy Library are consistent with the fire protection objectives established in nationally recognized fire protection codes and standards. This analysis is performed to establish a technical baseline for identification of fire protection deficiencies.

Kennedy Library is the campus student library at California Polytechnic State University. The facility provides resources and services in a variety of media to meet the needs of university students and faculty.

This analysis consists of a prescriptive analysis and a performance-based analysis. The prescriptive analysis is an analysis of the …

From Urban To Agriculture, Jacqueline V. Aenlle

Agricultural Education: Graduate Internship Reports

"From Urban to Agriculture" is a website utilizing a blog and podcast to connect with consumers and share reliable information about agriculture. In addition to covering specific topics such as organic production, dairy animal welfare, and honey production, this forum also address cross disciplinary topics such as media literacy and critical thinking. The website not only appeals to everyday consumers, it also provides resources for educators seeking to integrate a lesson on agricultural advocacy into their curriculum. The following report details the creation process for this website, development of blog content, acquisition of podcast materials, and future plans for the …

Graduate Internship Report - Cactus Ropes, Chelsey K. Bushnell

Agricultural Education: Graduate Internship Reports

This internship was a partnership between the Cal Poly Rodeo program and Cactus Ropes. I interned with marketing and promotion for Cactus Ropes. My main responsibility was managing and creating promotional jackpot ropings, creating promotional highlight videos for social media, promotional marketing ideas for the Poly Royal Rodeo, promotional highlight shots of the night at the rodeo, and involving Cactus Ropes with with Cal Poly Rodeo. I also participated in other aspects of promotions and events, including taking promotional photographs of rodeo athletes using Cactus Ropes, assisting in event planning, and promoting ropes and products. Besides organizing the awards given …

Planr.: Planar Learning Autonomous Navigation Robot, Gabrielle S. Santamorena, Daniel Kasman, Jesus Mercado, Ben Klave, Andrew Weisman, Anthony Fortner

Computer Engineering

PLANR is a self-contained robot capable of mapping a space and generating 2D floor plans of a building while identifying objects of interest. It runs Robot Operating System (ROS) and houses four main hardware components. An Arduino Mega board handles the navigation, while an NVIDIA Jetson TX2, holds most of the processing power and runs ROS. An Orbbec Astra Pro stereoscopic camera is used for recognition of doors, windows and outlets and the RPLiDAR A3 laser scanner is able to give depth for wall detection and dimension measurements. The robot is intended to operate autonomously and without constant human monitoring …

Cp Ewheel, Garrett Maxon, Adam Berg, Logan Griffith, Jacob Butler, Alexander Evans

Electrical Engineering

With an increasing demand for environmentally friendly transportation options, the bike market is larger than ever. According to bikeleague.org, from 2005 to 2013, the number of commuters using bikes has grown by 62%, and continues to rise. Regardless, commute time remains a barrier for many prospective users. Traditional bikes are useful in scenarios where the user only needs to travel a short distance. Electric bikes allow individuals to travel to farther destinations quicker, and with less effort. However, most electric bikes are rather expensive, typically ranging in price from one thousand to ten thousand dollars. Additionally, because the bike, motor, …

Dc-Dc Converter For Electric Vehicle, Jason Y. Zhou, Nicholas James Mah

Electrical Engineering

In this work, a DC-DC converter is designed for an electric vehicle. The DC-DC converter is designed to provide 500W with a 200-400V input and a 12-15V adjustable output. Electric vehicle sales are beginning to increase in popularity and the need for DC-DC converters to siphon power from the tractive system is not yet fully satisfied, especially for single-seater class vehicles. Additionally, improving performance in efficiency without sacrificing wide input voltage range can benefit future DC-DC converter designs. In the end, a forward active clamp DC-DC converter is designed and tested. Additionally, spreadsheet calculators, LTSpice simulations, and Matlab scripts were …

The Effect Of Vocal Fillers On Credibility, Communication Competence, And Likeability, Lea E. Gikas, Zachary T. Sutcliffe

Communication Studies

This study examines the impact of vocal fillers on a person’s perceived likeability, communication competence, professional credibility, and personal credibility. Previous studies have suggested that using filler words or discourse markers may decrease professional credibility and discredit communication competence. However, it is unknown how audience members of different genders will respond to the usage of vocal fillers in comparison to each other. A 2 x 2 factorial experimental design was constructed (N = 145) in which four audio recordings contained four responses to an interview question; the amount of vocal fillers were manipulated (absent or many) and the gender of …

Streets Of San Francisco: An Analysis Of The City's Transportation Network, Complete Streets Guidelines And Policies, Ian Xavier Connolly

City and Regional Planning

Transportation is a key element to everyday life, providing an efficient connection and movement of goods and people. While there are different modes of transportation, motor vehicles are still the preferred and highly used option, providing people the luxury of traveling to farther distances on their own time and in their own comfort. However, in a country where cities are increasingly becoming cores of pedestrian traffic, motor vehicles make these places less walkable, as well as produce pollution through their use of gasoline. At a time when we must continue to consider the safety and environmental aspects of transportation, we …

Keylime, Eli William Partker

Computer Engineering

Josh, Matt and I knew we wanted to develop a mobile app for our senior project because that is what we found ourselves to be most passionate about during our time here at Cal Poly. We started to think of problems we wanted to solve using an application and we came up with a couple ideas but chose to expand on one. Students come to Cal Poly every year new to the area and the food options San Luis Obispo provides. Many of the restaurants in SLO offer a variety of deals to the community and most of them to …

A Case Study Examining The Structure Of The Event Process At California Polytechnic State University, Ryan R. Baker

Master's Theses

The purpose of this study was to examine the structure of the event process on Cal Poly’s campus. An intrinsic case study method was used, and data were collected and analyzed using triangulation from three sources of information: documents, interviews, and participation research. Overall, the structure of the event management process on campus was found to be stable, but could use improvement. Cal Poly should consider establishing a specific, designated organization that would help centralize the event management process at Cal Poly. This organization could be in charge of training and updating event managers, approving events, monitoring volume of events …

The Effects Of Agricultural Waste-Based Compost Amendments In Organic Pest Management, Gregg T. Stephenson

Master's Theses

Soil-borne pests and pathogens, such as Verticillium dahliae, can devastate a wide range of annual and perennial crops. Current management options for organic production are limited and sustainable management of pathogens, weeds, and arthropods is important for staying profitable and reducing the use of harmful chemicals. Organic soil amendments play an important role in supplying some of the nutritional needs of vegetable crops and improving soil structure, while also contributing to pest control. The objective of this research was to determine the effects of grape and olive-based composts on soil pathogen load, arthropod communities, and weed biomass and diversity. …

Designing A Simulator For An Electrically-Pumped Organic Laser Diode, Robert Hulbert

Master's Theses

Organic semiconductors provide an alternative set of basis materials to fabricate electronic devices like PN Junctions, LEDs, and FETs. These materials have several benefits over traditional inorganic semiconductors including their mechanical flexibility, reliance on renewable resources, and inexpensive large-scale manufacturability. Despite the contemporary device implementations with organic semiconductors, a solid-state electrically-pumped organic laser diode does not exist. However, organically-based lasers do exist by utilizing the organic material strictly for optical gain. The challenge occurs when charge carriers appear in the organic material. The charge carriers must reach a concentration such that population inversion occurs producing optical gain. However, between the …

A 3-Dimensional In Silico Test Bed For Radiofrequency Ablation Catheter Design Evaluation And Optimization, Carolyn Teng

Master's Theses

Atrial fibrillation (AF) is the disordered activation of the atrial myocardium, which is a major cause of stroke. Currently, the most effective, minimally traumatic treatment for AF is percutaneous catheter ablation to isolate arrhythmogenic areas from the rest of the atrium. The standard in vitro evaluation of ablation catheters through lesion studies is a resource intensive effort due to tissue variability and visual measurement methods, necessitating large sample sizes and multiple prototype builds. A computational test bed for ablation catheter evaluation was built in SolidWorks® using the morphology and dimensions of the left atrium adjacent structures. From this geometry, the …

New England Slave Trader: The Case Of Charles Tyng, Paul J. Michaels

Master's Theses

Charles Tyng has been heralded as an American hero after the posthumous publication of his memoir, Before the Wind: The Memoir of an American Sea Captain, 1808-1833, in 1999. Recent research involving British Treasury report books from the nineteenth century suggest otherwise – that Tyng actively promoted and was engaged in the illicit trade of African captives. A Boston Brahmin, Tyng applied the lessons of his time at sea with Perkins & Company, the opium trading firm, to his occupation as an agent of notorious slave trading firms in Havana. This paper uses as evidence records of the captures …

Evaluation Of Human Umbilical Vein Endothelial Cells In Blood Vessel Mimics Through Changes In Gene Expression And Caspase Activity, Conor Charles Hedigan

Master's Theses

Blood vessel mimics (BVMs) are simple tissue engineered blood vessel constructs intended for preclinical testing of vascular devices. This thesis developed and implemented methods to characterize two of these components. The first aim of this thesis investigated the effect of cell culture duration and flow conditions on endothelial cell gene expression, especially regarding endothelial-to-mesenchymal transition (EndMT). A trend of decreased endothelial marker gene expression and increased mesenchymal marker gene expression would indicate EndMT. qPCR analysis revealed that increased cell culture duration did not result in EndMT, and in fact increased endothelial marker expression as cell culture duration increased. Disturbed flow …