Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Arts and Humanities (25987)
- Religion (8667)
- Social and Behavioral Sciences (8233)
- Mormon Studies (6557)
- German Language and Literature (6259)
-
- German Literature (6105)
- History (5519)
- Engineering (4855)
- Religious Education (4819)
- Life Sciences (4336)
- Physical Sciences and Mathematics (3435)
- Sociology (3057)
- European History (2729)
- Education (2551)
- European Languages and Societies (2505)
- Business (1949)
- Medicine and Health Sciences (1797)
- Psychology (1681)
- English Language and Literature (1492)
- Comparative Literature (1408)
- Mechanical Engineering (1345)
- Civil and Environmental Engineering (1183)
- Political Science (1145)
- Regional Sociology (1077)
- Music (1056)
- Family, Life Course, and Society (881)
- Plant Sciences (872)
- Computer Sciences (823)
- Philosophy (823)
- Renaissance Studies (803)
- Keyword
-
- Poetry (3770)
- Mormon studies (2914)
- Gedichte (2766)
- Primary (1436)
- Excellent (1423)
-
- Intermediate (1130)
- Young Adult (1126)
- Book review (1117)
- Preschool (1109)
- Outstanding (1064)
- Book of Mormon (1049)
- History (764)
- Dependable (638)
- Utah (578)
- Family (546)
- Friendship (486)
- Joseph Smith (482)
- Essay (467)
- Toddler (425)
- Religion (400)
- Education (398)
- Picture Book (354)
- United States (353)
- Mormon Church (348)
- Aufsatz (335)
- Writing (320)
- Arts and humanities (319)
- Mormons (315)
- Church of Jesus Christ of Latter-day Saints (314)
- Language (297)
- Publication Year
- Publication
-
- Theses and Dissertations (11126)
- Faculty Publications (6197)
- Journal of Undergraduate Research (5570)
- Children's Book and Media Review (5535)
- BYU Studies (4341)
-
- International Congress on Environmental Modelling and Software (3711)
- Poetry (3379)
- Great Basin Naturalist (2607)
- Inscape (2027)
- Journal of East Asian Libraries (1857)
- Western North American Naturalist (1782)
- Essays (1654)
- Comparative Civilizations Review (1378)
- Insights: The Newsletter of the Neal A. Maxwell Institute for Religious Scholarship (1374)
- The Bridge (1084)
- Religious Educator: Perspectives on the Restored Gospel (1042)
- Swiss American Historical Society Review (1020)
- Interpreter: A Journal of Latter-day Saint Faith and Scholarship (970)
- Quidditas (802)
- Review of Books on the Book of Mormon 1989–2011 (788)
- Prose Fiction (630)
- Journal of Book of Mormon Studies (628)
- Issues in Religion and Psychotherapy (615)
- Swiss American Historical Society Newsletter (549)
- Undergraduate Honors Theses (535)
- Journal of the Jussi Björling Societies of the USA & UK (499)
- Brigham Young University Prelaw Review (488)
- Student Works (429)
- Deseret Language and Linguistic Society Symposium (423)
- The Thetean: A Student Journal for Scholarly Historical Writing (392)
- Publication Type
Articles 7591 - 7620 of 72250
Full-Text Articles in Entire DC Network
How Scholars Are Using Social Media To Support Their Scholarship, Olga Maria Belikov
How Scholars Are Using Social Media To Support Their Scholarship, Olga Maria Belikov
Theses and Dissertations
This article-format dissertation focuses on how scholars use social media to support their scholarship. The first article is a scoping literature review that outlines current research. While overviewing an emergent field of literature, the article highlights motivations for using social media use, discusses benefits and drawbacks of this use for scholarship, explains how this discourse has evolved over time, and shares implications of what further topics can be investigated as well as implications for post-secondary institutions and scholars integrating social media use into their professional roles. In article two, I built a classifier and used it to analyze the Twitter …
Online Sexual Mindfulness Intervention For Black And Interracial Couples: A Pilot Study, Jenna M. Lawlor
Online Sexual Mindfulness Intervention For Black And Interracial Couples: A Pilot Study, Jenna M. Lawlor
Theses and Dissertations
Sexual mindfulness has been shown to improve couple's relationship and sexual satisfaction. Mindfulness research has mostly been conducted with White participants, largely leaving out the perspectives of diverse participants. This study piloted an online culturally-adapted version of the Sexual Mindfulness Project with Black and interracial couples (N=26 heterosexual individuals in a committed relationship from three different continents; age range 23€“44) to understand the program's acceptability and impacts. Qualitative interviews and quantitative surveys showed that couples enjoyed the program and experienced positive relational and sexual impacts post-intervention, including improved relationship satisfaction, sexual satisfaction, communication, and sexual mindfulness. Implications to improve the …
Quantum Decoherence In Time-Dependent Anharmonic Systems, Ty Beus
Quantum Decoherence In Time-Dependent Anharmonic Systems, Ty Beus
Theses and Dissertations
This dissertation studies quantum decoherence in anharmonic oscillator systems to monitor and understand the way the systems evolve. It also explores methods to control the systems' evolution, and the effects of decoherence when applicable. We primarily do this by finding the time evolution of the systems using their Lie algebraic structures. We solve for a generalized Caldirola-Kanai Hamiltonian, and propose a general way to produce a desired evolution of the system. We apply the analysis to the effects of Dirac delta fluctuations in mass and frequency, both separately and simultaneously. We also numerically demonstrate control of the generalized Caldirola-Kanai system …
Peer Educator Training Course, Hannah Call
Peer Educator Training Course, Hannah Call
Instructional Psychology and Technology Graduate Student Projects
The purpose of this design project is to help college students within Brigham Young University become qualified Peer Educators. Peer Educators work with other students who are in need of academic assistance. They help by offering tutoring services, responsive feedback, and holistic student support. Currently, around eighty student employees are working for the BYU Student Success Center as tutors. Prior to this project, these tutors offered help in specialized subjects, but they were not trained to offer any support beyond specific questions asked by students. They had not been trained in the holistic “Peer Educator” responsibilities and were instead trained …
Exploring The Perceptions Of School Teams Implementing Multi-Tiered Systems Of Support, Saanya Rajesh Lulla
Exploring The Perceptions Of School Teams Implementing Multi-Tiered Systems Of Support, Saanya Rajesh Lulla
Theses and Dissertations
Many schools are transitioning towards a preventative approach to meet the needs of at-risk learners with academic and/or behavioral concerns through the Multi-Tiered Systems of Support (MTSS) framework. This qualitative study explored the perceptions of the impacting factors for MTSS and the needs of building leadership teams through semi-structured interviews using a video conferencing-based online platform. Participants included 15 building administrators from school districts in a mountain west state of the United States. Interviews were transcribed and analyzed through thematic analysis. A total of four themes or impacting factors were identified. First, participants reported that MTSS relies on the district's …
Tensions And Pitfalls In The Depiction Of Multiracial Characters In Children's Picture Books: A Critical Content Analysis, Melody Green
Tensions And Pitfalls In The Depiction Of Multiracial Characters In Children's Picture Books: A Critical Content Analysis, Melody Green
Theses and Dissertations
The United States is becoming more and more multiracial, but little research attends to multiracial characters in children’s picture books. This research employed a critical content analysis using the lens of critical race theory to examine eight children’s picture books published after 2000. This study sought to answer two questions. First, using a critical race theory lens, what patterns and tensions emerge in the depictions of multiracial characters in children’s picture books? Secondly, how do the depictions of multiracial characters in children’s picture books perpetuate deconstructed conceptualizations of multiracial identity? Common themes that presented themselves in this study were (a) …
Effects Of Tackification Agents On Room Temperature Epoxy Mechanical Properties, Garen B. Murray
Effects Of Tackification Agents On Room Temperature Epoxy Mechanical Properties, Garen B. Murray
Theses and Dissertations
When laying up dry composite materials and aligning the fibers in the appropriate directions it can be a challenge due to the dryness of the fiber and mold design. Several commercial products are available to help fix plies to molds keeping the proper fiber orientation depending upon mold geometry. Prepreg and wet layups do not have this problem due to the inherent inclusion of a matrix in their manufacturing, dry materials have no added epoxy at the time of layup and are therefore in need of assistance maintain position. The purpose of this research is to determine if Super 77™ …
Effects Of Background Noise On The Spoken Language Of Young And Older Adults During Narrative Discourse, Erin Lecheminant
Effects Of Background Noise On The Spoken Language Of Young And Older Adults During Narrative Discourse, Erin Lecheminant
Theses and Dissertations
This study examined how different background noise conditions affected the spoken language production of young (18-25) and older (60-85) adults when performing a story retell task. Participants included 10 female and 10 male young adult (YA) participants, as well as 10 female and 10 male older adult (OA) participants. Participants retold stories in a silent baseline and five background noise conditions (conversation, monologue, phone call, cocktail, pink noise). Speech fluency and language production measures (cohesive and coherent utterances, lexical-phonological errors, grammatically correct words, Moving Average Type Token Ratio (MATTR), speech rate, and disfluent words) were compared between groups and across …
Towards Color-Based Two-Hand 3d Global Pose Estimation, Fanqing Lin
Towards Color-Based Two-Hand 3d Global Pose Estimation, Fanqing Lin
Theses and Dissertations
Pose estimation and tracking is essential for applications involving human controls. Specifically, as the primary operating tool for human activities, hand pose estimation plays a significant role in applications such as hand tracking, gesture recognition, human-computer interaction and VR/AR. As the field develops, there has been a trend to utilize deep learning to estimate the 2D/3D hand poses using color-based information without depth data. Within the depth-based as well as color-based approaches, the research community has primarily focused on single-hand scenarios in a localized/normalized coordinate system. Due to the fact that both hands are utilized in most applications, we propose …
Methods For Characterizing Groundwater Resources With Sparse In-Situ Data, Ren Nishimura
Methods For Characterizing Groundwater Resources With Sparse In-Situ Data, Ren Nishimura
Theses and Dissertations
Groundwater water resources must be accurately characterized in order to be managed sustainably. Due to the cost to install monitoring wells and challenges in collecting and managing in-situ data, groundwater data is sparse in space and time especially in developing countries. In this study we analyzed long-term groundwater storage changes with limited times-series data where each well had only one groundwater measurement in time. We developed methods to synthetically create times-series groundwater table elevation (WTE) by clustering wells with uniform grid and k-means-constrained clustering and creating pseudo wells. Pseudo wells with the WTE values from the cluster-member wells were temporally …
Being "Rightly Known": Otherness And The Ethics Of Reading In Charlotte Brontë'S Villette, Tin Yan Grace Lee
Being "Rightly Known": Otherness And The Ethics Of Reading In Charlotte Brontë'S Villette, Tin Yan Grace Lee
Theses and Dissertations
Villette (1853), Charlotte Brontë's last novel, is famously riddled with ambiguity: its narrator-protagonist, Lucy Snowe, avoids disclosing details about her childhood, fails to reveal to readers the identity of characters she recognizes from her past, and, at the end of the novel, refuses to confirm if her love interest, M. Paul, has died at sea after a storm. Believing Lucy's ambiguous narrative style to be a tool she uses to train readers to better understand her, many critics have focused their efforts on trying to interpret Lucy's silences and evasions "correctly," thereby turning themselves into Lucy's or Brontë's "ideal" authorial …
Speech Pause In People With Aphasia Across Word Length, Frequency, And Syntactic Category, Lana Mitchell
Speech Pause In People With Aphasia Across Word Length, Frequency, And Syntactic Category, Lana Mitchell
Theses and Dissertations
This study is an examination of how a word’s syntactic category, word length, and usage frequency might impact a speaker’s use of communicative pause. Previously collected between and within utterance language samples from 21 people with aphasia (Harmon, 2018) were evaluated in this study. Participants consisted of 11 individuals diagnosed with mild or very mild aphasia and 10 individuals with moderate aphasia;15 who exhibited fluent subtypes and 6 non-fluent subtypes of aphasia. Data from the Corpus of Contemporary American English (COCA) was used to code the word frequency and syntactic category of each word in the language samples. Generally, speakers …
An Exploratory Study Of Behavioral Engagement In People With And Without Aphasia: Comparisons And Relationships, Vivian Elisabeth Ward
An Exploratory Study Of Behavioral Engagement In People With And Without Aphasia: Comparisons And Relationships, Vivian Elisabeth Ward
Theses and Dissertations
Previous research suggests that attentional deficits could be the underlying cause of language impairments in people with aphasia (PWA) and that behavioral engagement ratings can be an accurate way to measure attention to specific tasks. Previous research also suggests that PWA have lower levels of behavioral engagement than neurologically healthy adults. Participants in the present study included 9 PWA and 18 neurologically healthy adults. This was an exploratory study investigating the relationships and differences between behavioral engagement and physiological measures, perceived arousal, and naming accuracy and response time in PWA and neurologically healthy adults. Participants completed a confrontational naming task …
The Effects Of Stimulus Type On Interpersonal And Intrapersonal Speech Perception In Typical Adults, Melannee Wursten Ipsen
The Effects Of Stimulus Type On Interpersonal And Intrapersonal Speech Perception In Typical Adults, Melannee Wursten Ipsen
Theses and Dissertations
Children with speech sound disorders (SSD) often have difficulties with speech perception. Speech perception is the ability to intake speech sounds and interpret them for meaning. Understanding children’s speech perception abilities is pertinent because children use perceptual skills to hone accurate production during SSD treatment. Different types of stimuli have been used in speech perception research. At present, it is unclear how different types of speech stimuli differentially impact speech perception in typical listeners or children with SSD. In this study, we investigated perceptual skills for different speech types in neurotypical adults to better understand how stimulus type impacts perception …
Diagnostic Accuracy Of Nonword Repetition Tasks For The Clinical Assessment Of Spanish-English Dual Language Learners: A Preliminary Investigation, Audrey Czirr
Theses and Dissertations
Nonword repetition (NWR) has demonstrated significant potential as a less-biased language assessment measure for dual language learners (DLLs). However, there are currently no available guidelines for the use of NWR in a clinical setting. The purpose of this preliminary study is to develop initial recommendations for the clinical use of NWR tasks by determining the diagnostic accuracy and optimal cut-off scores for two NWR tasks and scoring methods, and to evaluate the clinical feasibility of NWR as an assessment measure. Participants included 23 DLL students with and without language disorder between the ages of 6 and 8. Spanish and English …
The Behavioral And Neurophysiologic Relationships Between Sensory Processing And Autistic Traits In Emerging Adults, Savanah Calton
The Behavioral And Neurophysiologic Relationships Between Sensory Processing And Autistic Traits In Emerging Adults, Savanah Calton
Theses and Dissertations
The majority of individuals diagnosed with Autism Spectrum Disorder (ASD) experience sensory processing difficulties that are also associated with greater presence of autistic traits, psychiatric difficulty, and intolerance of uncertainty (IU). These relationships are also expressed in the neurotypical (NT) population, termed the Broader Autism Phenotype (BAP), and present with impacts to daily functioning/well-being just as prominently. However, little is known concerning the neurophysiologic nature of these behavioral relationships, especially in young adults. Thus, the purpose of the current study was to examine the behavioral and neurophysiologic nature of the relationships between sensory processing, autistic traits, and related behavioral functions …
Motivation Across Platforms, Mariia Shishmareva
Motivation Across Platforms, Mariia Shishmareva
Theses and Dissertations
Motivation in language learning has been studied for quite a long time. However, the main focus has been on motivation in face-to-face learning environments. Motivation in online learning can be different due to many factors. This study compared how a language instructor used motivational strategies in face to-face vs. Zoom classes; and how students reacted to these motivational strategies. For these purposes the Motivational Orientation of Language Teaching (MOLT) was used for observations. Results showed that while the teacher used many of the same motivational strategies in both sections, some categories like Social Chat, Referential Questions and Volunteering had significantly …
The Effects Of Relatedness Support On Motivational Profiles In Rural Vs. Urban Physical Education Students, Corbin D. Stringam
The Effects Of Relatedness Support On Motivational Profiles In Rural Vs. Urban Physical Education Students, Corbin D. Stringam
Theses and Dissertations
The purpose of this study was to examine the degree to which relatedness support affects motivational profiles in rural vs. urban physical education (PE) students. Participants included rural (n=177) and urban (n=431) junior high/high school students (grades 5-12) from Alberta, a western province in Canada (n=508), and Utah, a state in the intermountain west of the USA (n=100). This cross-sectional study measured and assessed students’ basic psychological needs of student-to-student relatedness, student-to-teacher relatedness, competence, and autonomy using a revised version of the Basic Psychological Needs Scale (BPNS-R). Situational motivation was measured and assessed using the Situational Intrinsic Motivation Scale – …
Auditory Brainstem Response In Autistic Children: Potential Implications For Sensory Processing, Madelyn Cate
Auditory Brainstem Response In Autistic Children: Potential Implications For Sensory Processing, Madelyn Cate
Theses and Dissertations
Autistic people frequently experience sensory processing difficulties. For many on the autism spectrum, such difficulties can significantly impact important functions and quality of life. We are only beginning to understand the neural mechanisms of atypical sensory processing. However, one established way to measure certain levels of auditory processing is with auditory brainstem responses (ABR). While ABR has been primarily hypothesized in the current literature as a means of early detection/diagnosis in autism, additional research is needed to determine the ABR’s utility in examining sensory processing in this population. Thus, we evaluated ABR in 19 young children with autism during various …
Examining The Preliminary Validity Of A Dynamic Assessment Of Narrative Language In Mandarin Chinese, Lok Yee Sarah Cheung
Examining The Preliminary Validity Of A Dynamic Assessment Of Narrative Language In Mandarin Chinese, Lok Yee Sarah Cheung
Theses and Dissertations
The purpose of this thesis was to examine the preliminary validity of a newly developed dynamic assessment of narrative language in Mandarin Chinese. Two studies are reported in this thesis. Study 1 included 31 second grade participants and Study 2 included 43 first grade participants. All participants were enrolled in a Chinese immersion program in an elementary school in Utah. A dynamic assessment of narrative language was administered to each participant in Mandarin Chinese. A teacher rating was also included in Study 1. Results indicated that the dynamic assessment investigated in this thesis demonstrated some similar characteristics with other valid …
"A Poem Is A Gesture Toward Home": Formal Plurality And Black/Queer Critical Hope In Jericho Brown's The Tradition, Kaitlin Hoelzer
"A Poem Is A Gesture Toward Home": Formal Plurality And Black/Queer Critical Hope In Jericho Brown's The Tradition, Kaitlin Hoelzer
Theses and Dissertations
Jericho Brown's The Tradition (2019), which won the Pulitzer Prize for poetry, includes four duplexes, a poetic form of Brown's own invention that combines the sonnet and the blues. Made of fourteen lines separated into seven couplets, the duplex is a complex structure comprised of sets of indents and repeated lines. Brown's use of disparate source forms to create a new form altogether challenges the supremacy of a singular, white American literary tradition, putting it into conversation with other traditions in order to critique its historically racist and heterosexist boundaries. As he does so, Brown works not to abolish "the …
Women's Response To Spousal Pornography Use: A Grounded Theory, Misha Duncan Crawford
Women's Response To Spousal Pornography Use: A Grounded Theory, Misha Duncan Crawford
Theses and Dissertations
Empirical research suggests that married women may more commonly experience spousal pornography use as a relational attachment threat and are more likely to experience negatively associated relational outcomes such as distress and loss of trust. The purpose of this study was to develop a grounded theory of women’s response to concealed spousal pornography use. This study included the experiences of 30 women who reported spousal pornography use as a threat to relational attachment and demonstrated evidence of individual and relational healing thereafter. The research question, “How do women describe the experience of learning of their spouse’s pornography use and the …
Improving Transition Care: A Transition Toolkit Implementation Project, Julieanne Cox, Bret Lyman, Matt Anderson, Marie Prothero
Improving Transition Care: A Transition Toolkit Implementation Project, Julieanne Cox, Bret Lyman, Matt Anderson, Marie Prothero
Student Works
The purpose of this project was to develop an easy-to-use transition toolkit for clinics serving children and young adults with chronic illnesses who are transitioning from a pediatric model of care to an adult model of care. GotTransition’s six core elements served as a guiding framework for the toolkit. The toolkit was developed through an iterative process with substantial stakeholder input. Stakeholders included patient, parents, clinicians, and transition care experts. Project evaluation data were gathered from clinic stakeholders using a quantitative post-then survey based on GotTransition’s six core elements of transition care, as well as three open-ended questions. All six …
Two New Late Quaternary Avifaunas From The East-Central Great Basin With The Description Of A New Species Of Falco, Steven D. Emslie, Jim I. Mead
Two New Late Quaternary Avifaunas From The East-Central Great Basin With The Description Of A New Species Of Falco, Steven D. Emslie, Jim I. Mead
Western North American Naturalist
We report 2 new late Quaternary avifaunas from cave deposits in Snake Valley, White Pine County, eastern Nevada, that provide new records of extinct and extant species in the east-central Great Basin. These avifaunas collectively represent at least 24 species, including the most northern inland record of California Condor (Gymnogyps californianus) in western North America and a new species of kestrel (Falco sp.) described herein. Two extralimital living species also were identified—the Harlequin Duck (Histrionicus histrionicus) and Snowy Owl (Bubo scandiacus)—and are the first fossil records of these species in the Great Basin. …
Synthesis And Applications Of Α,Β-Dehydroamino Acid-Containing Peptides, Diego A. Moya
Synthesis And Applications Of Α,Β-Dehydroamino Acid-Containing Peptides, Diego A. Moya
Theses and Dissertations
Yaku’amide A (YA) is a linear anticancer peptide that is rich in bulky dehydroamino acids (ΔAAs) and β-hydroxyamino acids (β-OHAAs). In our recent total synthesis of YA, we featured a one-pot anti dehydration–azide reduction–O→N acyl transfer process for the stereospecific construction of Z- and E- ∆Ile residues. Despite previous total syntheses and our efforts, the synthesis of YA remains lengthy. Via computational studies, we identified two analogue peptides that closely resemble the conformation of YA. The use of simpler and symmetrical bulky ΔAAs such as dehydrovaline (ΔVal) and dehydroethylnorvaline (ΔEnv) as surrogates of ∆Ile, along with azlactone chemistry for their …
Wild Ixalan: A Creative Case Study On Mythology, Magic, And More, Lincoln Teichert
Wild Ixalan: A Creative Case Study On Mythology, Magic, And More, Lincoln Teichert
Undergraduate Honors Theses
Magic: The Gathering, a subsidiary of Hasbro, releases packs of cards periodically, unified by a cast of dozens of characters who can travel from plane to plane—the rough equivalent of interstellar travel—but games feature battles between these powerful mages (represented by players) across the multiverse of fictional locations. Before quarterly set releases, short stories are published on Magic’s website, a form of content marketing that has spurred sales for over a quarter-century. Magic draws on myths from across the world, along with diverse geographies and technological development. This paper offers an overview of trading card games, sketches what a Magic …
Amino Acids As Alternatives To Emulsifying Salts In Processed Cheese Analogues, Jeremy Thomas Pack
Amino Acids As Alternatives To Emulsifying Salts In Processed Cheese Analogues, Jeremy Thomas Pack
Theses and Dissertations
Background: Manufacturers have used emulsifying salts universally in the processed cheese industry since James L. Kraft patented the first processed cheese in 1916. My objective was to find alternative ingredients to replace emulsifying salts in processed cheese formulations; the product would follow "clean-labeling" trends and lower the final formulation's sodium content. Materials and Methods: My experiments followed conventional processed cheese formulations to create experimental batches, which were compared to positive and negative controls for significance. Textural, rheological, and melting tests evaluated objective cheese parameters. We observed subjective sensory properties through qualitative descriptive analysis, consumer acceptance panels, and focus groups. Results: …
Progress On Static Structures In Leaky Mode Waveguides, Manusha Korimi
Progress On Static Structures In Leaky Mode Waveguides, Manusha Korimi
Theses and Dissertations
Virtual reality (VR) head-mounted displays provide a high definition, immersive experi-ence to the viewer. However, most existing technologies have flaws like bulky design and vergence-accommodation conflict that may cause stress in the neck muscles, posture issues, nausea, motion sickness and dizziness. Similarly, augmented reality (AR) displays, which use transparent light modulators, exist, but they possess low field of view and a limited number of discrete depth planes when wide field of view and continuous depth would be ideal. The ultimate goal of my research is use leaky mode waveguide devices to create wide-view angle, transparent near eye holographic displays for …
The Regulation Of Atg9a-Mediated Aggrephagy By An Ulk1-Independent Atg13-Atg101 Complex, Joshua Youngs
The Regulation Of Atg9a-Mediated Aggrephagy By An Ulk1-Independent Atg13-Atg101 Complex, Joshua Youngs
Undergraduate Honors Theses
Aggrephagy, a type of autophagy, is an essential cellular process by which protein aggregates are collected and broken down in the lysosome. Protein aggregates are implicated in several diseases including Alzheimer’s disease, diabetes, and cancer. Here, we investigate the ATG13-ATG101 protein complex, a sub-complex of the canonical ULK1 complex whose regulatory role in aggrephagy is not completely understood. We also develop a protein fragment complementation (PFC) assay using the biotin ligase TurboID to study the functions of the ATG13-ATG101 complex with increased specificity. We demonstrate that ATG13 is required for optimal degradation of p62-ubiquitin condensates. We also show that a …
A Molecular Taxonomy Of Cottus In Western North America, Michael K. Young, Rebecca Smith, Kristine L. Pilgrim, Daniel J. Isaak, Kevin S. Mckelvey, Sharon Parkes, Jacob Egge, Michael K. Schwartz
A Molecular Taxonomy Of Cottus In Western North America, Michael K. Young, Rebecca Smith, Kristine L. Pilgrim, Daniel J. Isaak, Kevin S. Mckelvey, Sharon Parkes, Jacob Egge, Michael K. Schwartz
Western North American Naturalist
The taxonomy of sculpins (Cottus, Cottidae) remains one of the last major unresolved puzzles in the systematics of North American freshwater fishes. We used molecular approaches to identify candidate taxa and their distribution across western North America. We crowd-sourced the collection of specimens (n = 8272) via outreach to biologists in the western United States and Canada. From that collection, we sequenced—at up to 2 mitochondrial and 2 nuclear genes—a subset (n = 4009) of specimens from most basins in the western United States, added sequences from public sequence databases, and applied an array of species …