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Using Rna-Sequencing To Explore Mechanistic Markers, New Therapeutics, And Immune Imbalance: A Study Of Cancer And Autoimmunity Through The Lens Of Triple Negative Breast Cancer, Systemic Lupus Erythematosus, And B-Cell Non-Hodgkin's Lymphoma, Naomi Lydia Rapier-Sharman Jan 2025

Using Rna-Sequencing To Explore Mechanistic Markers, New Therapeutics, And Immune Imbalance: A Study Of Cancer And Autoimmunity Through The Lens Of Triple Negative Breast Cancer, Systemic Lupus Erythematosus, And B-Cell Non-Hodgkin's Lymphoma, Naomi Lydia Rapier-Sharman

Theses and Dissertations

Cancer and autoimmune diseases both impose a substantial healthcare burden on the US and world populations. In 2016, there were over 17 million cases of cancer, leading to nearly nine million deaths. Additionally, autoimmune diseases cause substantial mortality and morbidity and are present in 3-5% of the general population. Despite the increased attention scientists now give diseases that are impacted by immune imbalance, we have yet to find regimens to treat the core cause(s) of tissue dysfunction without drastically decreasing the quality of life for many patients with either cancer or autoimmune disease. For instance, anti-CD19 Chimeric Antigen Receptor (CAR) …


Transfer Learning For Thickener Control, Samuel Arce Munoz, John Hedengren Jan 2025

Transfer Learning For Thickener Control, Samuel Arce Munoz, John Hedengren

Faculty Publications

Thickener control is a key area of focus in the minerals processing industry, particularly due to its crucial role in water recovery, which is essential for sustainable resource management. The highly nonlinear nature of thickener dynamics presents significant challenges in modeling and optimization, making it a strong candidate for advanced surrogate modeling techniques. However, traditional data-driven approaches often require extensive datasets, which are frequently unavailable, especially in new plants or unexplored operational domains. Developing data-driven models without enough data representative of the dynamics of the system could result in incorrect predictions and consequently, unstable response of the controller. This paper …


Research Process Toward The Creation Of Transgenic Beetles, Taylor Coffman, Christian Mccombs, Jonah Jex, Chris Daley, Brian D. Jensen, Sandra Hope Ph.D Jan 2025

Research Process Toward The Creation Of Transgenic Beetles, Taylor Coffman, Christian Mccombs, Jonah Jex, Chris Daley, Brian D. Jensen, Sandra Hope Ph.D

Library/Life Sciences Undergraduate Poster Competition 2025

Create a generalized efficient procedure for the reliable creation of transgenic insects.


Front Matter Jan 2025

Front Matter

Interpreter: A Journal of Latter-day Saint Faith and Scholarship

No abstract provided.


Chapter 1: Book Of Mormon Animals, Matthew Roper Jan 2025

Chapter 1: Book Of Mormon Animals, Matthew Roper

Interpreter: A Journal of Latter-day Saint Faith and Scholarship

No abstract provided.


Chapter 4: Ancient Culture, Matthew Roper Jan 2025

Chapter 4: Ancient Culture, Matthew Roper

Interpreter: A Journal of Latter-day Saint Faith and Scholarship

No abstract provided.


Chapter 5: Book Of Mormon Names, Matthew Roper Jan 2025

Chapter 5: Book Of Mormon Names, Matthew Roper

Interpreter: A Journal of Latter-day Saint Faith and Scholarship

No abstract provided.


Chapter 9: Concluding Observations, Matthew Roper Jan 2025

Chapter 9: Concluding Observations, Matthew Roper

Interpreter: A Journal of Latter-day Saint Faith and Scholarship

No abstract provided.


Full Issue Jan 2025

Full Issue

Interpreter: A Journal of Latter-day Saint Faith and Scholarship

No abstract provided.


The Flimsiest Show On Earth, Blake T. Ostler Jan 2025

The Flimsiest Show On Earth, Blake T. Ostler

Interpreter: A Journal of Latter-day Saint Faith and Scholarship

Every so often an anti-Mormon book comes along that lowers the bar for attacks on the faith. How the Book of Mormon Came to Pass is one such work. It relies on speculation, conjecture, and tenuous connections to render, out of whole cloth, a hypothesis for the Book of Mormon’s creation that is almost laughable.


A Fitting Tribute To The Prophet Of The Restoration, Steven L. Olsen Jan 2025

A Fitting Tribute To The Prophet Of The Restoration, Steven L. Olsen

Interpreter: A Journal of Latter-day Saint Faith and Scholarship

Joseph Smith: A Life Lived in Crescendo is one of the most extensive and ambitious scholarly works on the founder of The Church of Jesus Christ of Latter-day Saints. Its twenty-one essays address various issues relating to the culmination of the Prophet’s ministry. They provide diverse and profound insights worthy of examination by serious students of the latter-day Restoration.


Latter-Day Saint Theology And The Problem Of Evil, Val Larsen, Newell D. Wright Jan 2025

Latter-Day Saint Theology And The Problem Of Evil, Val Larsen, Newell D. Wright

Interpreter: A Journal of Latter-day Saint Faith and Scholarship

The classical formulation of God as the sole, self-existent Being and ground of all that exists poses a philosophical problem. If God is omniscient and omnipotent, why does evil exist? Why does he not save humankind from moral and natural evil? If we embrace the full set of classical assumptions of creedal Christianity, these questions have no satisfactory answer and God cannot be absolved of responsibility for evil. This paper reviews and rejects several classical and modern philosophical formulations that try to solve the problem of evil. It then argues that the problem of evil dissolves if we accept Restoration …


Honorable Intentions With An Unreliable Methodology: Lucas’S Response Underscores The Problems, Jeff Lindsay Jan 2025

Honorable Intentions With An Unreliable Methodology: Lucas’S Response Underscores The Problems, Jeff Lindsay

Interpreter: A Journal of Latter-day Saint Faith and Scholarship

James Lucas has made a passionate response to the negative review I offered for his and Jonathan Neville’s book By Means of Urim & Thummim. Though we agree on many important issues, there are some troubling gaps that readers of their book need to understand. Some of these issues may be illustrated in the methodology of Lucas’s response. In general, the unreliable methodology and its often extreme, unnuanced approach to dealing with complex, unclear issues must be challenged, as painful as that has been. The complaints in my review remain intact if not further underscored by Lucas’s response. The …


Joseph And Oliver Told The Truth About The Translation: A Response To Brant Gardner’S And Jeff Lindsay’S Reviews, James W. Lucas Jan 2025

Joseph And Oliver Told The Truth About The Translation: A Response To Brant Gardner’S And Jeff Lindsay’S Reviews, James W. Lucas

Interpreter: A Journal of Latter-day Saint Faith and Scholarship

Two recent reviews of By Means of the Urim & Thummim: Restoring Translation to the Restoration by Jeff Lindsay and Brant Gardner seriously misrepresent the book’s argument. Perhaps most significantly, they largely sidestep the book’s central thesis that the statements by Joseph Smith and Oliver Cowdery that the Book of Mormon was translated from the plates using the “Urim and Thummim” interpreters which God provided with the plates should be at the center of any account of the Book of Mormon’s production. Prioritizing problematic and unreliable seer stone accounts conflicts with the testimonies of these primary eyewitnesses, and thus is …


“Get Thou Up Into The Temple”: Receiving Revelation And Becoming Holy In The House Of The Lord, Matthew L. Bowen Jan 2025

“Get Thou Up Into The Temple”: Receiving Revelation And Becoming Holy In The House Of The Lord, Matthew L. Bowen

Interpreter: A Journal of Latter-day Saint Faith and Scholarship

Psalms 15:1–5, 24:2–3, and 48:1 [MT 2], as temple hymns of the Jerusalem Temple, are consistent with other texts such as Isaiah 2:2–3 and Genesis 22:14, which envision the holy temple as the “mountain of the Lord” into which one must ritually ascend. The examples of Moses, Nephi, Jacob, and others who ascended into this “mountain” demonstrate that this ascent facilitates the reception of divine revelation necessary in our mortal journey to become holy through the Atonement of Jesus Christ. This sacred ascent is necessary for our eventual, individual, and collective “perfection” in Christ, and it is one that he …


The Covenant Path Of The Ancient Temple In 2 Nephi 31:19–20, Jeffrey M. Bradshaw Jan 2025

The Covenant Path Of The Ancient Temple In 2 Nephi 31:19–20, Jeffrey M. Bradshaw

Interpreter: A Journal of Latter-day Saint Faith and Scholarship

In this article, I discuss how the ancient analogue to what President Nelson has called “the covenant path” might be seen in the Book of Mormon and elsewhere in scripture not so much as a journey of covenant-keeping that takes us to the temple but as a journey that takes us through the temple. Throughout the Book of Mormon, observant readers will find not only the general outline of the doctrine of Christ but also corresponding details about the covenant path as represented in temple layout and furnishings. Nowhere is this truth better illustrated than in 2 Nephi 31:19–20 where …


Chiasmus In The Book Of Jarom, Stephen Kent Ehat Jan 2025

Chiasmus In The Book Of Jarom, Stephen Kent Ehat

Interpreter: A Journal of Latter-day Saint Faith and Scholarship

Jarom strongly evidences the use of chiasmus to structure his short book. This paper seeks to uncover, display, and discuss the chiastic patterning of the book and hopefully suggests an enhanced understanding of the hidden beauty and deep meaning of this brief but important text. The book of Jarom indeed offers more than what may otherwise be revealed by only a cursory reading of its fifteen verses. Awareness of the chiastic pattern of the text reinforces an understanding of Jarom’s important message.


Finding Nephi’S Ore, Bradley R. Larsen Jan 2025

Finding Nephi’S Ore, Bradley R. Larsen

Interpreter: A Journal of Latter-day Saint Faith and Scholarship

Khor Kharfot and Wadi Sayq are in the region that has become the premiere candidate for Nephi’s Old-World Bountiful. Out of the several matching criteria that has led to this opinion, the one that may be the weakest has been the identification of readily available ore in the area that Nephi could have used to manufacture the tools necessary to build his ship. This investigation, conducted in February 2023, found several distinct examples of iron ores suitable for ”smelting” in the form of float, all pointing to deposits yet to be located. Additionally, I review the investigation of Dr. Revell …


“Our Hands Have Handled”: Ensuring The Reassuring Doctrine Of The Resurrection In The Lucan And Johannine Writings, Matthew L. Bowen Jan 2025

“Our Hands Have Handled”: Ensuring The Reassuring Doctrine Of The Resurrection In The Lucan And Johannine Writings, Matthew L. Bowen

Interpreter: A Journal of Latter-day Saint Faith and Scholarship

The Lucan and Johannine writings emphasize the literalness and physicality of the resurrection of Jesus Christ. This emphasis does not represent an emerging Christology from an earlier, inchoate conception of Jesus and the meaning of his life. Rather, it reflects an effort to defend the doctrine of the resurrection—of Christ and humanity—against the increasing cultural and intellectual pressures of middle Platonism. Nephi’s vision of the tree of life, which included seeing a “great and abominable church” and its formation among “the nations of the Gentiles” (1 Nephi 13:4–9) matches well with late first- and second-century apostate movements that “made war” …


Perspectives On The Soteriological Problem Of Evil: Nuancing The “Universalist” Theologies Of Henri De Lubac And Joseph Smith, Timothy Gervais Jan 2025

Perspectives On The Soteriological Problem Of Evil: Nuancing The “Universalist” Theologies Of Henri De Lubac And Joseph Smith, Timothy Gervais

Interpreter: A Journal of Latter-day Saint Faith and Scholarship

Since the discovery of the new world by Christian European explorers during the age of discovery, the increasingly global community of the modern age has confronted Christian theologians with difficult soteriological questions. These questions have caused many Christian adherents to abandon conceptions of a uniquely Christian salvation in favor of theological positions of religious pluralism. Other Christian theologians have confronted these issues through creative inclusivist theological constructs that expand the offer of salvation to those who may not have professed Christianity in their mortal life. These inclusivist theologies are uniquely suited to address modern concerns about the salvation of non-believers …


“When Ye Shall Rend That Veil Of Unbelief”: A Typological Reading Of Ether 3 And 4, Matthew Scott Stenson Jan 2025

“When Ye Shall Rend That Veil Of Unbelief”: A Typological Reading Of Ether 3 And 4, Matthew Scott Stenson

Interpreter: A Journal of Latter-day Saint Faith and Scholarship

In the book of Ether, the prophet Moroni “Christianizes” the Jaredite story, inserting extensive Christian elements into an original text that predates the house of Israel, the Nephite nation, and the Christian era. In this paper, a typological and intertextual method is used to show how Moroni uses the words of Christ in Ether 3 and 4 to exhort his Gentile readers to embrace the Nephite record when it is manifest to them that they might receive even greater things (divine truths). Specifically, Moroni uses the brief account of the brother of Jared atop Mount Shelem to illustrate how Gentiles …


Full Issue Jan 2025

Full Issue

Interpreter: A Journal of Latter-day Saint Faith and Scholarship

No abstract provided.


The Heyday Of The Mia Latter-Day Saint Youth Programs In The Postwar Era, Lisa Olsen Tait, Amber C. Taylor Jan 2025

The Heyday Of The Mia Latter-Day Saint Youth Programs In The Postwar Era, Lisa Olsen Tait, Amber C. Taylor

BYU Studies

On Saturday, June 16, 1956, a crowd of twenty thousand spectators filled the University of Utah football stadium, nestled against the foothills to the east of Salt Lake City, to witness the Mutual Improvement Association (MIA) Dance-Drama Festival of The Church of Jesus Christ of Latter-day Saints. Hopes were high that the weather would hold, since Friday night’s performance had been canceled because of rain. The weather did cooperate, and for over two hours, a massive procession of brightly costumed young women and men, representing almost every stake in the Church, presented a spectacular program of intricately choreographed dances and …


Full Issue Jan 2025

Full Issue

Interpreter: A Journal of Latter-day Saint Faith and Scholarship

No abstract provided.


From Revolution To Restraint: The Domestic Origins Of France's Foreign Policy Of Non-Intervention In 1830, Annabelle Crawford Jan 2025

From Revolution To Restraint: The Domestic Origins Of France's Foreign Policy Of Non-Intervention In 1830, Annabelle Crawford

Sigma: Journal of Political and International Studies

Many prominent theories of international conflict would predict that in the aftermath of the 1830 revolutions, France should have gone to war with the conservative powers of Europe on behalf of Belgium. However, despite military and political opportunities for war, incentives to spread or counter France’s new liberal ideology, and misunderstandings between France and the other European powers, French leaders and leaders of the conservative great powers alike actively pursued a European peace. This presents a theoretical puzzle: why wasn’t there a conflict between the French revolutionary state and other European states in the aftermath of the July Revolution?


Full Issue Jan 2025

Full Issue

Sigma: Journal of Political and International Studies

No abstract provided.


National Renewal Through Fertility:, Austin Siler Jan 2025

National Renewal Through Fertility:, Austin Siler

BYU Asian Studies Student Journal

Japan has been facing fertility decline over the past several decades. Indeed, this decline constitutes a severe demographic crisis due to its birth rates falling to record lows year after year. Low birth rates have been correlated with economic and societal instability. As Akram (163) posits: “The combination of unfavorable demographics and poor economic growth has resulted in a secular decline” which has no current sign of shifting based on current policy. The government has implemented numerous policies to try and tackle this issue, but with little success. Japan’s population as of 2024 is estimated to be 125 million and …


Full Issue Jan 2025

Full Issue

BYU Asian Studies Student Journal

No abstract provided.


The Wonder Is Scripture, Jared Halverson Jan 2025

The Wonder Is Scripture, Jared Halverson

BYU Studies

It’s an honor to be associated in any way with this institute, as it’s my second-favorite thing named after Elder Neal A. Maxwell. The first is my eldest son, whose middle name was an obvious choice, largely because my wife loves Elder Maxwell even more than she loves me, which might be a problem were it not for the fact that I agree with her. I once spent so much time in this library creating a compilation of Elder Maxwell’s talks that by the time I was finished, my wife had called the police to report a missing person. When …


“Struck With Wonder And Amazement” On Reading The Book Of Mosiah, Joseph M. Spencer Jan 2025

“Struck With Wonder And Amazement” On Reading The Book Of Mosiah, Joseph M. Spencer

BYU Studies

The Wonder of Scripture”: that’s the title of this lecture series.1 Book of Mormon scholar that I am, that title draws my mind to a passage in our keystone scripture. It’s a passage where the word “wonder” is used in connection with people’s responses to sacred records—to scripture. Tucked away somewhere most of us wouldn’t think to look, the Book of Mormon stages a remarkable scene that’s precisely about the wonder of scripture. I can’t help seeing that as just a little too appropriate, so I’d like to examine that scene. I’m going to argue that Mormon, serving simultaneously in …