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Exploring The Mechanism Of Increased Survival In Rb1-Mutant Glioblastoma Multiforme, Lucia Wesemann
Exploring The Mechanism Of Increased Survival In Rb1-Mutant Glioblastoma Multiforme, Lucia Wesemann
Undergraduate Honors Theses
Glioblastoma Multiforme (GBM) is an incredibly invasive and particularly lethal central nervous system cancer. Recent work has shown that GBM patients with mutated RB1 have greater overall survival. A proposed mechanism for the improved prognosis of this molecular subgroup is mainly supported by previous research that is not specific to GBM. I utilize the Clinical Proteomic Tumor Analysis Consortium (CPTAC) dataset to interrogate this mechanism using GBM-specific data. The mechanism is largely not supported by the CPTAC GBM dataset, and the trend of significantly improved overall survival in RB1-mutant GBM patients is not validated here. This study highlights the …
The Effects Of Combining Β-Lactam Antibiotics And Mefloquine In Multi-Drug Resistant Pseudomonas Aeruginosa, Kayla C. Maas
The Effects Of Combining Β-Lactam Antibiotics And Mefloquine In Multi-Drug Resistant Pseudomonas Aeruginosa, Kayla C. Maas
Theses and Dissertations
Pseudomonas aeruginosa, a notorious opportunistic pathogen, is a leading cause of hospital-acquired infections. The newest generation of β-lactam antibiotics, the carbapenems, are often used to treat multi-drug resistant (MDR) P. aeruginosa infections. Treatment of P. aeruginosa has become increasingly difficult due to its remarkable ability to resist antibiotics through various intrinsic and acquired mechanisms. Physicians rely on a limited group of antibiotics to treat these infections, but many P. aeruginosa isolates are evolving to become resistant to all available antibiotics, including carbapenems. The multifaceted mechanisms underlying P. aeruginosa antibiotic resistance include β -lactamases, efflux pumps, altered membrane porins, and antibiotic …
Geological And Geophysical Model Of The Sand Wash Extensional Decollement, Utah, Brigham Louis Cardon
Geological And Geophysical Model Of The Sand Wash Extensional Decollement, Utah, Brigham Louis Cardon
Theses and Dissertations
The Sand Wash Fault Zone (SWFZ) in the southern Uinta Basin is a significant extensional fault zone exhibiting complex deformation patterns. Our study integrates detailed structural analyses with a broader tectonic model to elucidate the tectonic evolution of the region. The SWFZ, extending over 34 km with a NW-SE strike, is underlain by an extensional decollement. Substantial deformation is observed in the upper layers, notably within the S2 sandstone of the Eocene Green River Formation. The deformation diminishes with depth, terminating at the oil-rich Mahogany oil shale zone, below which minimal deformation is observed. Our tectonic model, developed primarily through …
Disability And News: How Audiences Respond To Disabled Messengers In A Newcast, Daniel J. Andersen
Disability And News: How Audiences Respond To Disabled Messengers In A Newcast, Daniel J. Andersen
Theses and Dissertations
Starting in the 1960s, many communications theories sprung to life in response to social movements that thrived in that era. While those theories were applied to movements such as gender equality, the equal rights movement, and racial and ethnic minority recognition efforts, the disability community has largely been left outside of academic exploration. Building off of decades of stereotype and representation research within communications psychological theories, this study used eye tracking to understand how audiences respond to seeing disabled newscasters. Using quantitative analysis and experimental design to expose participants to a news anchor in a wheelchair, this study built off …
Exploring The Link Between Travel Behavior And Mental Health, Emily Kae Youngs
Exploring The Link Between Travel Behavior And Mental Health, Emily Kae Youngs
Theses and Dissertations
This study explores the critical link between travel behavior and mental health, focusing on young adults who have expressed suicidal ideation. By analyzing how daily activities and movement patterns impact mental well being, the research aims to explore travel related mental health approaches for individuals. The importance of this work lies in its potential to improve the quality of life for individuals by informing more personalized and effective mental health strategies. Through comprehensive data analysis and statistical modeling, the research aims to uncover insights into how travel behavior influences motivation levels and mental well-being across different neurological and physiological groups. …
Systematic Review Of Digital Activity Schedule Use In Individuals With Autism And Intellectual Disability, Adelaide Wahlquist Hammond
Systematic Review Of Digital Activity Schedule Use In Individuals With Autism And Intellectual Disability, Adelaide Wahlquist Hammond
Theses and Dissertations
The purpose of this systematic review of using digital activity schedules as an intervention in individuals with autism spectrum disorder and intellectual disabilities is to determine to what extent the current research shows it to be an effective intervention. For articles to be included in this review, they had to use a digitally presented activity schedule, the activity schedule could not be a task analysis of a single activity or a group visual schedule, and the intervention must have been carried out with individuals with autism or intellectual disabilities. Studies meeting the inclusion criteria totaled 17 studies with a total …
Raw Data For M5h2r1 Origami Flasher Deployment Tests, Philip Klocke
Raw Data For M5h2r1 Origami Flasher Deployment Tests, Philip Klocke
ScholarsArchive Data
These data sets contain raw force data from the deployment tests of a case study origami Flasher.
A Comparative Illustration Of Trip- And Activity-Based Modeling Techniques, Steven Hayden Atchley
A Comparative Illustration Of Trip- And Activity-Based Modeling Techniques, Steven Hayden Atchley
Theses and Dissertations
Activity-based travel demand models are generally considered superior to their trip-based counterparts, as activity-based models (ABMs) explicitly model individuals in contrast to the aggregate nature of trip-based models. There have been a number of comparisons between trip- and activity-based models, but these comparisons focus almost exclusively on the technical ability of the two model types, while not considering the practical benefits an ABM may or may not have to a transportation agency. This research performs a more holistic comparison between trip- and activity-based models, focused specifically on the practical differences between model types, both in terms of usability and capability …
A Proposal For A Compassionate Behavior Consultation - A Pilot Study, Danina Lynne Thatcher
A Proposal For A Compassionate Behavior Consultation - A Pilot Study, Danina Lynne Thatcher
Theses and Dissertations
Teachers frequently encounter disruptive or other challenging behavior in their classrooms, which often results in poor outcomes for both teachers and students. Behavior consultation is frequently used to assist teachers in managing challenging behavior. However, it is difficult for teachers to implement behavioral interventions with consistent fidelity, even with consultative support. This pilot study utilized a multiple-baseline design to evaluate the effects of a compassionate behavior consultation on teachers' implementation fidelity of evidence-based classroom management practices in three junior high classrooms. It also assessed the teacher's ratings of the social validity of the consultation process and resulting interventions. A compassionate …
Using Neural Networks To Reconstruct Temperature From Fluorescent Data For Use In Bio-Microfluidics, Jacob G. Kullberg
Using Neural Networks To Reconstruct Temperature From Fluorescent Data For Use In Bio-Microfluidics, Jacob G. Kullberg
Theses and Dissertations
It has been theorized that Quantum Dots (QD) can solve the temperature sensor issue with microfluidic devices. Quantum Dots are nano-sized semiconducting crystals with a radius of an excited electron-hole pair. When a QD is excited by a short wavelength light, the QD produces fluorescent light. As the temperature of the dot changes, the dot expands and shifts the fluorescent spectrum. Quantum Dots are small enough to be placed inside the microfluidic devices, and a spectrometer can measure the change in fluorescent data. This fluorescent data can be used to create fluorescent images corresponding to the QD temperature. These fluorescent …
Proposing A Matrix For Selecting Security Tools For Small Businesses, Nathan Jonathon Rowbotham
Proposing A Matrix For Selecting Security Tools For Small Businesses, Nathan Jonathon Rowbotham
Theses and Dissertations
Small businesses are increasingly under threat of cybersecurity attacks. An increasingly long list of tools with different purposes and coverage are available to help. But it can be difficult to choose which tools to use, particularly for a small business that may lack financial resources, expertise, and time. Research literature focuses on providing frameworks to follow to protect a business generally. Some research considers an aspect of creating a Security Operations Center. Other research describes the creation of a Security Operations Center as a Service with all the components the researchers deemed necessary. None of the current research literature seems …
Exploring The Impact Of Collaborative Communities Among High School Principals, William T. Sherwood
Exploring The Impact Of Collaborative Communities Among High School Principals, William T. Sherwood
Theses and Dissertations
Principals of large high schools are faced with a job that is constantly increasing in demands and complexity; with few options for highly relevant professional development, good resources to aid in problem solving, and/or effective supports for social/emotional well-being. In this qualitative case study, I examine four different school districts involving 20 principals from large high schools that are involved in different iterations of collaborative communities (CC). Participants were interviewed regarding their perceptions of the benefits and challenges of the CC in which they were engaged. Participants also shared the practices and protocols present in their CC contributing to those …
Perspectives And Experiences Of Emergent Bilingual Parents Concerning Their Engagement With Their Child's Teachers And School, Jordan Foss Roberts
Perspectives And Experiences Of Emergent Bilingual Parents Concerning Their Engagement With Their Child's Teachers And School, Jordan Foss Roberts
Theses and Dissertations
Emergent bilinguals (EBs) represent the fastest-growing population in U.S. public schools (Tarasawa & Waggoner, 2015). Many EB parents face linguistic or cultural barriers when engaging with teachers and are often excluded from their children's classrooms because of their English learner status. This qualitative study analyzes EB or English learner parents' perspectives of their child's teachers and school. Critical Sociocultural Theory (C-SCT) was used to view EB parent engagement practices (Moje & Lewis, 2007). The research processes were based on Creswell and Creswell's (2018) methodology using a focus group and interview design to understand these participants' educational interactions. Data was collected …
Raising Hope: A Preliminary Investigation Of Hope-Strengthening Parenting, Anna Sellers Calley
Raising Hope: A Preliminary Investigation Of Hope-Strengthening Parenting, Anna Sellers Calley
Theses and Dissertations
Hope Theory defines hope as a cognitive-motivational process of seeking and obtaining goals through agency thinking and pathway building, with substantive connection to many desirable outcomes. While hope is theorized to begin developing early in life, this assumption has never been empirically investigated. This is due to limitations in established hope measurement. There is an additional gap in the research surrounding the role of parents in the development of hope. In this study, I address each of these gaps by utilizing a novel measure of hope in early childhood and running a multiple linear regression model to investigate potential connections …
Survey Of Parental Perspectives In Dialogic Book Reading Practices In Parents Of Preschool-Aged Children, Hind Otba Taiseer Alsboul
Survey Of Parental Perspectives In Dialogic Book Reading Practices In Parents Of Preschool-Aged Children, Hind Otba Taiseer Alsboul
Theses and Dissertations
This study focused on how early literacy practices at home affect children's language development by looking at the reading habits and dialogic book reading practices of parents with preschool-aged children. Parents were asked to consider and report on their literacy practices at home. They were asked to focus on their current reading habits with their children and how they observed their children paying attention during book-sharing sessions. This study was a part of a bigger project that developed and carried out dialogic reading workshops for parents. Preschool connections and friends spread a survey with parent-report questions in order to collect …
Design And Validation Of Sensing Knee Sleeve Rehabilitation Device Utilizing Large Deflection Strain Gauges, Kurt Christian Jensen
Design And Validation Of Sensing Knee Sleeve Rehabilitation Device Utilizing Large Deflection Strain Gauges, Kurt Christian Jensen
Theses and Dissertations
Total knee arthroplasty (TKA) procedures are increasingly common in the US and globally. However, rehabilitation outcomes may be negatively affected by limited access to physical therapy and patients' tendency to not fully adhere to recommended exercises between therapy sessions. This study aims to develop a remote system to aid rehabilitation, building upon recent sensor development at Brigham Young University, providing physical therapy-like biofeedback during unsupervised at-home exercises. The system developed by this research consists of three primary components: (1) a sensor array for measuring leg/knee biomechanics, (2) a machine learning algorithm to predict knee flexion angle from the sensor data, …
Chinese Mandarin-Speaking Teachers' Voices In Chinese Dual Language Immersion Programs Responding To American Classroom Management Relationship Issues, Wu-Ting Chen
Theses and Dissertations
This study examines Chinese Mandarin-speaking teachers' voices concerning classroom management (CM) in Chinese Dual-Language Immersion (DLI) classrooms in Utah, United States. Most Chinese-Mandarin-speaking teachers in Chinese DLI programs do not have a lot of experience in understanding American Western culture-style CM and therefore encounter new challenges in managing classroom behavior. Moreover, most American students, parents, teachers, and administrators do not understand the Chinese teachers' classroom expectations, nor do they realize that such behavioral expectations are a full part of learning the Chinese-Mandarin language and culture together. Using a sociocultural theoretical perspective and discourse analysis, this study provides descriptive evidence identifying …
Investigating Cloth Sculpting For Simulation Control In Virtual Reality, Matthew S. Bishop
Investigating Cloth Sculpting For Simulation Control In Virtual Reality, Matthew S. Bishop
Theses and Dissertations
Artists require control and predictability over physically based simulations to create their required animation. This control can lead to reduced iteration time to get the desired simulation results. Controlling cloth simulations can require manual effort to create goal keyframes for control algorithms to match. Current techniques and research utilize a keyboard and mouse to create these goal keyframes. Other research has looked at using a virtual reality (VR) head-mounted display with controllers to improve the experience of completing similar animation tasks. However, we are not aware of any research that attempts to use VR as a tool to assist artists …
Vco Calibration Techniques And Design Of A 0.12-V Ultra-Low Supply Analog-To-Digital Converter, Shea Smith
Vco Calibration Techniques And Design Of A 0.12-V Ultra-Low Supply Analog-To-Digital Converter, Shea Smith
Theses and Dissertations
Many analog-to-digital converters (ADC) quantize inputs using a voltage-controlled-oscillator (VCO). These VCO-based ADCs leverage time-domain processing to shape quantization noise and mismatch, which further increases their appeal. Despite these advantages, achieving good performance with a VCO-based ADC remains a significant challenge due to the nonlinear transfer characteristics of the voltage-to-frequency (V-F) conversion. VCO-based ADCs widely utilize coarse-fine readout to save power and hardware compared to counter-only converters. However, the timing mismatch due to the clock skew between the coarse and fine quantizers can lead to significant reconstruction errors. Chapter 2 proposes a digital calibration circuit to detect and correct coarse-fine …
Subspace Decomposition Of Linear Secrecy Codes, David Robert Joseph Hunn
Subspace Decomposition Of Linear Secrecy Codes, David Robert Joseph Hunn
Theses and Dissertations
We introduce a new method for the study of linear codes, termed subspace decomposition, which provides new insights into code structure and performance. Briefly, subspace decomposition comprises the evaluation of complex properties of a linear code by evaluating simple properties of its constituent subspaces. We find that this technique has application to a number of problems in coding theory. When applied to the problem of evaluating the performance of secrecy codes, subspace decomposition provides an efficient method for computing the equivocation of coset codes over the binary erasure wiretap channel. It is also especially efficient in computing the chi squared …
Partisanship, Security, And Global Status: Anatomy Of Taiwan’S March 19 Shooting Conspiracy Theories, William Martindale
Partisanship, Security, And Global Status: Anatomy Of Taiwan’S March 19 Shooting Conspiracy Theories, William Martindale
Undergraduate Honors Theses
Previous research has shown how belief in particular conspiracy theories is subject to their salience to believers. Using the example of Taiwan’s March 19 shooting conspiracy theories, I show in this paper that salience is created by appealing to existing collective memory. Additionally, I show that conspiracy theory spreaders help to reinforce the elements of collective memory that make their conspiracy theories salient. Using evidence from primary sources and a representative survey sample, I demonstrate the relevance of three contextual elements in belief in conspiracy theories about the March 19 shooting. These can be summarized as Partisanship, Security, and Global …
Effects Of Vascular Risk Factors On Risk For Dementia And Stroke After Late-Onset Epilepsy, Evan Thacker
Effects Of Vascular Risk Factors On Risk For Dementia And Stroke After Late-Onset Epilepsy, Evan Thacker
BYU Research Development Office Research Networking Conference
Areas of Interest: Brain health, neuroepidemiology, cardiovascular epidemiology, statistics
Future Projects, Michael S. Robinson
Future Projects, Michael S. Robinson
BYU Research Development Office Research Networking Conference
Areas of Interest: Preventive Health: Immunizations/Vaccines; Immunization Hesitance; Immunization Uptake
Idr: Manifold Alignment For Improved Alzheimer's Prediction Using Multi-Modal Data, Jake Rhodes
Idr: Manifold Alignment For Improved Alzheimer's Prediction Using Multi-Modal Data, Jake Rhodes
BYU Research Development Office Research Networking Conference
Areas of Interest: Machine learning, data science, deep learning, random forests, manifold learning
Greg Snow Research Interests, Greg Snow
Greg Snow Research Interests, Greg Snow
BYU Research Development Office Research Networking Conference
Areas of Interest: Statistical support for any University Research
Advancing Understanding And Support For Families Experiencing Chronic Illness And Disability, Christine Platt
Advancing Understanding And Support For Families Experiencing Chronic Illness And Disability, Christine Platt
BYU Research Development Office Research Networking Conference
Areas of Interest: Health of children and families, families raising children with chronic illnesses and disabilities, social determinant of health, foster care system
A Wee Bit Of Cleanup: Updating Scottish Locality Pages On The Familysearch Research Wiki, Garrett Mast
A Wee Bit Of Cleanup: Updating Scottish Locality Pages On The Familysearch Research Wiki, Garrett Mast
Undergraduate Honors Theses
While the FamilySearch Research Wiki provides a valuable resource for genealogical references for countries across the globe, its potential is bottlenecked by having a small pool of editors compared to sites like Wikipedia. The webpages for each Scottish parish have fallen by the wayside, with most not receiving any material update in a decade. This project reflection highlights the choices made and processes taken in order to revitalize the Scottish locality pages of the Research Wiki following the verification of civil, ecclesiastical, and probate jurisdictions for each parish in Scotland. This included making an interactive jurisdiction map in ArcGIS …
Comparing Gas Composition From Fast Pyrolysis Of Live Foliage Measured In Bench-Scale And Fire-Scale Experiments, David R. Weise, Thomas H. Fletcher, Timothy J. Johnson, Wei Min Hao, Mark Dietenberger, Marko Princevac, Bret W. Butler, Sara S. Mcallister, Joseph J. O'Brien, E Louise Loudermilk, Roger D. Ottmar, Andrew T. Hudak, Akira Kato, Babak Shotorban, Shankar Mahalingham, Tanya L. Myers, Javier Palarea-Albaladejo, Stephen P. Baker
Comparing Gas Composition From Fast Pyrolysis Of Live Foliage Measured In Bench-Scale And Fire-Scale Experiments, David R. Weise, Thomas H. Fletcher, Timothy J. Johnson, Wei Min Hao, Mark Dietenberger, Marko Princevac, Bret W. Butler, Sara S. Mcallister, Joseph J. O'Brien, E Louise Loudermilk, Roger D. Ottmar, Andrew T. Hudak, Akira Kato, Babak Shotorban, Shankar Mahalingham, Tanya L. Myers, Javier Palarea-Albaladejo, Stephen P. Baker
Faculty Publications
Background. Fire models have used pyrolysis data from oxidising and non-oxidising environments for flaming combustion. In wildland fires pyrolysis, flaming and smouldering combustion typically occur in an oxidising environment (the atmosphere). Aims. Using compositional data analysis methods, determine if the composition of pyrolysis gases measured in non-oxidising and ambient (oxidising) atmospheric conditions were similar. Methods. Permanent gases and tars were measured in a fuel-rich (non-oxidising) environment in a flat flame burner (FFB). Permanent and light hydrocarbon gases were measured for the same fuels heated by a fire flame in ambient atmospheric conditions (oxidising environment). Log-ratio balances of the measured gases …
The Effect Of Context Diversity In Virtual Reality Environments On Speech Motor Learning In A Person With Aphasia And Apraxia Of Speech, Shelby Keeler Holloway
The Effect Of Context Diversity In Virtual Reality Environments On Speech Motor Learning In A Person With Aphasia And Apraxia Of Speech, Shelby Keeler Holloway
Theses and Dissertations
This study explored the effect of contextual diversity on speech motor learning in an individual with apraxia of speech (AOS) using virtual reality (VR). One 62-year-old participant with severe AOS participated in the study where he practiced monosyllabic CVC words in both consistent and diverse VR environments. Kinematic, acoustic, and perceptual data were collected and evaluated for evidence of learning. Kinematic data were collected using electromagnetic articulography where sensors were glued to the participant's upper lip, lower lip, tongue blade, and tongue tip and were tracked with high precision. In addition, acoustic and perceptual data were collected using a microphone …
Transient Heat Transfer To Rolling Or Sliding Drops On Inclined Heated Superhydrophobic Surfaces, Joseph Furner, Daniel Maynes, Brian D. Iverson, Julie Crockett
Transient Heat Transfer To Rolling Or Sliding Drops On Inclined Heated Superhydrophobic Surfaces, Joseph Furner, Daniel Maynes, Brian D. Iverson, Julie Crockett
Faculty Publications
The thermal transport to drops that roll or slide down heated superhydrophobic surfaces is explored. High-speed infrared imaging is performed to provide time-resolved measurement of the heat transfer to the drop. Data are obtained for drops moving along smooth hydrophobic and structured superhydrophobic surfaces. Both post and rib style structures with surface solid fractions ranging from 0.06 to 1.0 are considered. The inclination angle of the surfaces was varied from 10 deg to 25 deg, and the drop volume was varied from 12 to 40 µL. The measurements reveal that the drop speed is a strong function of both the …