Digital Commons Network^™

Hyperarousal And Beyond: New Insights To The Pathophysiology Of Insomnia Disorder Through Functional Neuroimaging Studies, Daniel Kay, Daniel J. Buysse

Faculty Publications

Neuroimaging studies have produced seemingly contradictory findings in regards to the pathophysiology of insomnia. Although most study results are interpreted from the perspective of a “hyperarousal” model, the aggregate findings from neuroimaging studies suggest a more complex model is needed. We provide a review of the major findings from neuroimaging studies, then discuss them in relation to a heuristic model of sleep-wake states that involves three major factors: wake drive, sleep drive, and level of conscious awareness. We propose that insomnia involves dysregulation in these factors, resulting in subtle dysregulation of sleep-wake states throughout the 24 h light/dark cycle.

Electrophysiological Endophenotypes And The Error-Related Negativity (Ern) In Autism Spectrum Disorder: A Family Study, Scott A. Baldwin, Ann Clawson, Mikle South, Michael J. Larson

Faculty Publications

We examined the error-related negativity (ERN) as an endophenotype of ASD by comparing the ERN in families of ASD probands to control families. We hypothesized that ASD probands and families would display reduced-amplitude ERN relative to controls. Participants included 148 individuals within 39 families consisting of a mother, father, sibling, and proband. Robust ANOVAs revealed non-significant differences in ERN amplitude and behavioral performance among ASD probands relative to control youth. In subsequent multiple regression analyses group and kinship (proband, sibling, mother, father) did not significantly predict ΔERN (error minus correct ERN) or behavioral performance. Results do not provide evidence for …

Best Practice For Treatment Of Vaccination Side-Effects With Antipyretic And Analgesic Medications, Lacey M. Eden, Meridith G. Lind, Karlen E. Luthy

Student Works

Nurse Practitioners (NPs) are on the frontlines providing parental education regarding vaccines. While there are several reasons for vaccine hesitancy, the potential side-effects of vaccine administration, such as pain and/or elevated temperature, are often cited as a parental concern. According to research, prophylactic administration of an antipyretic/analgesic medication, such as acetaminophen, reduces vaccine side-effects when administered prior to or at the time of vaccination. Additionally, the evidence that prophylactic administration of antipyretic/analgesic medication decreases antibody response to vaccinations is insufficient at this time. Thus, NPs should reassure parents that an antipyretic/analgesic medication can be administered prior to or at the …

Dual Mechanism For Toughening And Sustained Aminoglycoside Elution From A Polyphosphate Hydrogel, Dwight D. Lane, Russell J. Stewart Phd

Biomedical Engineering Western Regional Conference

No abstract provided.

Cocoa Procyanidin And Β-Cell Proliferation, Whitney Harris, Alonzo Cook Phd, Michael Scott Brashaw Iii, Jeffrey Brown, Kyril Cole, Kody Hasebi, Ysabella Del Rosario, Sara Werner, Bryan Samuel Witt

Biomedical Engineering Western Regional Conference

This presentation explains an experiment that attempts to provide a more thorough understanding on the effect of cocoa procyanidin on β-Cell proliferation in diabetic rats in order to advance the treatment of diabetes.

Serum Comp And The Inflammatory Environment Of The Knee Before And After Exercise-Induced Load, Alyssa Evans, Robert D. Hyldahl, Sarah T. Ridge, Sunku Kwon, Ty J. Hopkins, Eric R. Robinson, Matthew K. Seeley

Biomedical Engineering Western Regional Conference

The purpose of this study was to determine how accurately serum COMP represents inflammatory cytokine levels, within the knee, before and after exercise.

Cytokines included: GM-CSF, IFNa2, IL-10, IL-12p40, IL-13, IL-15, IL-1ra, IL1b, IL1a, IL-4, IL-6, IL-8, IP-10, MCP-1, MIP-1a, MIP-1b and IL-17.

Computational Characterization Of Blood Vessel Strain In Wire Myography, Sameer S. Nandikar, M Converse, K L. Monson

Biomedical Engineering Western Regional Conference

Blood vessels, and the mechanical forces that act on them, play a key role in both health and disease. As a consequence, the mechanical properties of vessels have been under study for over a century. A variety of approaches have been used to define vessel properties, including stretching of vessel rings to study circumferential behavior, a configuration commonly used in wire myography. The objective of the present study was to develop a finite element model to quantify strains throughout a vessel ring during such loading.

Structural Mrsa Resistance Through Carbon-Infiltrated Carbon Nanotube Coating Of External Fixator Pins, Jaclyn Larsen, Stephanie Morco, Brian Jensen, Anton Bowden

Biomedical Engineering Western Regional Conference

No abstract provided.

High-Speed Video Capture Of Anterior Cruciate Ligament Tear, Steven L. Cook, Devon T. Smith

Biomedical Engineering Western Regional Conference

High-speed Video Capture of Anterior Cruciate Ligament Tear

Engineering Fret Biosensors For Microrna Presence/Absence Analysis, Nicholas E. Larkey, Sean M. Burrows

Biomedical Engineering Western Regional Conference

No abstract provided.

Bssfp Elliptical Signal Model With Grappa Parallel Imaging, Grayson Tarbox, Joseph Valentine, Meredith Taylor, Neal Bangerter

Biomedical Engineering Western Regional Conference

In magnetic resonance imaging, balanced steady-state free precession acquisition using the elliptical signal model geometrical solution can be combined with a GRAPPA parallel imaging reconstruction that preserves phase information to shorten scan times.

Difference Image Ultra-Short Echo Time T2* Mapping Using A 3d Cones Trajectory, Amin Nazaran, Grayson Tarbox, Randy Hartley, Neal Bangerter

Biomedical Engineering Western Regional Conference

This study introduces a methodology for detecting subtle variations in tissues with very rapid T2* decay through a difference image ultra-short T2* mapping technique using a 3D cones k-space trajectory. The new method is demonstrated in both a normal and surgically repaired Achilles tendon. The resulting UTE images are differenced and T2* values were calculated using a mono-exponential least squares fit on a voxel by voxel basis. The ultrashort T2* maps yield very consistent short T2* values in healthy tendon of 0.3-0.5 ms, while notable variations and elevations of T2* values are observed in surgically repaired tendon.

The Recovery Glove System- A Sensor Driven Glove With Interactive Games For Fine Motor Skill Disabilities, Brian Lee, Oscar Ledezma, Jonathan Rey, Nicholas Alvarado, Deborah Won

Biomedical Engineering Western Regional Conference

Hand mobility is commonly impaired in stroke victims. Treatment for hand impairment range from therapist-guided physical exercises to robotically controlled exoskeletons. However, A more effective treatment which actually restores hand mobility is by encouraging patients to carry out hand movements themselves.We have designed an Arduino based hand therapy device in which the user interacts with a computer graphic interface (CGI) game controlled by a glove was embedded with a force sensing resistor (FSR) at each of the fingertips except for the thumb. The interactive therapy guides the user through exercises and provides live, quantitative information by which the stroke patient …

Heart Pump Modelling: Design Of Pulsatile Flow Phantoms, Olivia Coiado, Kevin Jones, Parker Schibel, Nicolas De Almeida

Biomedical Engineering Western Regional Conference

The purpose of this project is to build a model, which mimics physiological conditions of the human cardiovascular system in order to simulate the parameters of the human heart in vivo. For this project, it was developed a flow phantom with vessel mimicking material, as well as blood-mimicking and tissue-mimicking fluid. Phantoms in general are specifically designed objects involving dedicated biomaterials to simulate special realistic circuits of human beings. To develop the flow phantom, low-priced biomaterials for blood mimicking fluid, tissue mimicking, and vessel mimicking material was researched.

Keywords: Cardiovascular system, heart pump, modelling, pulsatile.

A Longitudinal Examination Of Parental Psychological Control And Externalizing Behavior In Adolescents With Adolescent Internalized Shame As A Mediating Variable, Iesha Renee Nuttall

Theses and Dissertations

The purpose of this study was to examine the relationship between parental psychological control and adolescent externalizing behavior with adolescent internalized shame acting as a mediating variable. Gender differences were also examined. Three hundred eleven two-parent families with an adolescent were included in this study, 154 were male adolescents (Mean age at wave 6 = 16.28 years, SD = .98) and 157 were female adolescents (Mean age at wave 6 = 16.21 years, SD = .99). Results indicate that parental psychological control for both mothers and fathers at wave 4 was positively related to adolescent externalizing behavior for both boys …

Privilege As Blind Spot: Carl Jung, The Red Book, And The"Collective Unconscious", Laura L. M. Fair-Schulz, William E. Herman

Swiss American Historical Society Review

Carl Gustav Jung's monumental Liber Novus or The Red Book journal, begun in 1914 and published posthumously in 2009, presents the viewer with a dazzling array of painted images. 1 The project references both his accumulated and specialized knowledge as a theorist and practitioner of psychoanalysis, as well as the personal explorations of his own "subconscious" mind . It also reveals contextually his privilege of being able to undertake such a work.

José, Joe, Zé Carioca: Walt Disney's Good Neighbor Colonial "Monument" In Brazil, Andrew Kelly Nelson

Theses and Dissertations

Although Walt Disney's early animated feature films were successful, a variety of economic, operational, and external forces required him to continually be on the cutting edge of new ideas and technologies in order for his studio to continue operations. Latin America became the studio's source of inspiration in the early 1940s, sprouting from Walt Disney's involvement with the Office of the Coordinator of Inter-American Affairs. Saludos Amigos and The Three Caballeros were the result. While many critics have decried Disney's involvement in Latin America as being an apparatus of cultural imperialism and economic exploitation, they almost universally give him credit …

The Effect Of Time Of Day Of Chronic Exercise On Neural Response To Visual Food Cues, Jessica Taylor Davies

Theses and Dissertations

This study examined the effect of an 8-week, progressive exercise intervention on neural responses, specifically N2 amplitude as a measure of inhibitory control, to pictures of food. Healthy women ages 18-44 years were randomized to a morning (AM) exercise group or evening (PM) exercise group. The AM group did moderate-to-vigorous intensity exercise on 4 days per week between 6:30 and 9:30 a.m. while the PM group had the identical volume of exercise between 6:30 and 9:30 p.m. Neural responses, eating behaviors, cardiovascular fitness outcomes, and body weight/composition were measured at baseline and after the 8-week intervention. The N2 amplitude in …

Psychological Well-Being Among Latter-Day Saint Polynesian American Emerging Adults, Melissa Lynn Aiono

Theses and Dissertations

There is a dearth of psychological research with Polynesian populations in the United States Research on this population is needed to meet the demands of this increasingly growing population. This study aims to investigate the psychological well-being of an understudied Latter-day Saint (LDS) Polynesian American emerging adult group in order to better provide them with cultural-specific professional psychological services. The sample included 327 LDS Polynesian American emerging adults ranging from 18 to 26 years of age (191 females, 136 males). Specifically, this study examines the associations among coping strategies, religiosity, ethnic identity, depression, anxiety, and self-esteem. An online questionnaire was …

Implicit Family Process Rules Specific To Eating-Disordered Families, Mallory Rebecca Wolfgramm

Theses and Dissertations

Family environment is a significant factor in the development of eating disorders in young-adult females. Clinical experience, research and theories about eating disorders indicate that constrictive implicit process rules within a family are correlated with eating-disordered families. This study identified implicit family process rules that are unique to eating-disordered families and how well these rules predict membership in eating-disordered and non-eating-disordered families. One hundred and two families (51 eating-disordered and 51 comparison families) participated in the study. Mothers, fathers, young-adult female children, and siblings in each family completed the Family Implicit Rules Profile (FIRP). The design included cluster analysis of …

Strategic Silence: Withholding Certification Status As A Hypocrisy Avoidance Tactic, W. Chad Carlos, Ben William Lewis

Faculty Publications

We examine why organizations that obtain prominent certifications may at times elect not to publicize them. Drawing on the impression management literature, we argue and show that concerns about being perceived as hypocritical may cause organizations to strategically withhold their certification status. Using a longitudinal panel of corporations that were members of the Dow Jones Sustainability Index, a prominent environmental certification, we show that in the face of reputational threats, organizations are less likely to publicize their certification status when the threat appears to directly contradict the claims implied by the certification. Our findings suggest that the threat of hypocrisy …

Comparison Of Testosterone Replacement Therapy Medications For Treatment Of Hypogonadism, Karlen Beth Luthy, Chris Williams, Donna S. Freeborn, Aaron Cook

Faculty Publications

Testosterone replacement therapy (TRT) is one treatment option for men with hypogonadism. When TRT is prescribed, effectiveness, patient compliance, cost, and potential side effects should be considered and utilized to develop an individualized treatment plan. Depo-testosterone is the most cost-efficient TRT option and is only administered every 2 weeks which may improve patient compliance, although the dose interval can be adjusted to once per week. Androderm is the most efficacious TRT medication, with up to 92% of patients reaching normal testosterone levels. Testim and Vogelxo have the fewest reported side effects. We recommend depo-testosterone as a first line treatment option.

Commentary: "How Much Is That Player In The Window? The One With The Early Birthday?" Relative Age Influences The Value Of The Best Soccer Players, But Not The Best Businesspeople, Luca Fumarco, Benjamin G. Gibbs

Faculty Publications

Fuelled by Gladwell's (2008), researchers have expanded their gaze beyond sports for evidence of the Relative Age Effect: that something as arbitrary as the month you were born in has important consequence for later life success. In line with Furley et al. (2016), we agree that any RAE outside of sports deserves closer scrutiny, but unlike Furley et al., we argue that we should not expect to find evidence of RAE for labor market outcomes in the first place, because there is not sufficient evidence of uniform age cut-offs in school.

Deuterateer: A Tool For Quantifying Peptide Isotope Precision And Kinetic Proteomics, Bradley C. Naylor, Michael T. Porter, Elise Wilson, Adam Herring, Spencer Lofthouse, Austin Hannemann, Stephen R. Piccolo, Alan L. Rockwood, John C. Price

Faculty Publications

Motivation

Using mass spectrometry to measure the concentration and turnover of the individual proteins in a proteome, enables the calculation of individual synthesis and degradation rates for each protein. Software to analyze concentration is readily available, but software to analyze turnover is lacking. Data analysis workflows typically don’t access the full breadth of information about instrument precision and accuracy that is present in each peptide isotopic envelope measurement. This method utilizes both isotope distribution and changes in neutromer spacing, which benefits the analysis of both concentration and turnover.

Results

We have developed a data analysis tool, DeuteRater, to measure protein …

Combined Aphasia And Apraxia Of Speech Treatment (Caast): Systematic Replications In The Development Of A Novel Treatment, Julie L. Wambaugh, Sandra Wright, Shannon C. Mauszycki, Christina Nessler, Dallin Bailey

Faculty Publications

Purpose: The purpose of this investigation was to examine the effects of a modified version of a newly developed therapy for aphasia and acquired apraxia of speech (AOS), Combined Aphasia and Apraxia of Speech Treatment (CAAST).

Method: Four speakers with chronic AOS and aphasia received CAAST in the context of multiple baseline designs. Dependent variables included language measures (i.e. production of correct information units (CIUs)) and speech production measures (i.e. speech intelligibility and percent correct consonants (PCC) in sentence repetition).

Result: Three of the participants demonstrated improved CIU production with treated picture sets and two also demonstrated generalization to untreated …

Greater Memory Impairment In Dementing Females Than Males Relative To Sex Matched Healthy Controls, Shawn D. Gale, Leslie Baxter, Juliann Thompson

Faculty Publications

Previously we demonstrated sex differences in episodic memory in healthy elderly and suggested that normative data be separated by sex. The present study extended the exploration of sex differences on memory measures into two clinical populations, Mild Cognitive Impairment (MCI) and Alzheimer's disease (AD). Seventy-six subjects with MCI and 101 subjects with AD diagnosed by a multidisciplinary team were included. These two groups were also compared to a group of 177 healthy elderly control participants. Sex differences on the Rey Auditory Verbal Learning Test (RAVLT) (total and delayed recall) raw scores and Brief Visuospatial Memory TestRevised (BVMT-R) were demonstrated within …

Ghosts, Sebastian Shiraishi

Children's Book and Media Review

Catrina doesn’t believe in ghosts. Or that’s what she thought, until her family decided to move to northern California due to her sister Maya’s Cystic Fibrosis, a disease that affects breathing and digestion. The small town of Bahia de la Luna is full of ghosts, particularly around an abandoned Spanish Mission. The two sisters, along with their new friend Carlos, go explore and talk to the ghosts, but Maya’s health keeps on declining so she can’t attend their annual celebration for the dead. Catrina decides to go to the party, where she meets Jose, an eight-year-old ghost, and they decide …

Relational Aggression And Marital Quality: A Five-Year Longitudinal Study, Sarah M. Coyne, David A. Nelson, Jason S. Carroll, Nathan J. Smith, Chongming Yang, Hailey G. Holmgren, Chad Johnson

Faculty Publications

Relational aggression occurs in many different contexts, including in romantic relationships. The current study examined associations between two subtypes of relational aggression (love withdrawal and social sabotage) and marital quality over a 5-year time period. Participants consisted of 311 married couples who completed a number of questionnaires on relational aggression and relationship quality once a year over a 5-year period. Results revealed that relational aggression was highly stable over time and that women used more relational aggression than men. Men’s use of social sabotage and love withdrawal were bidirectionally related to both partners’ perceptions of poor marital quality over time. …

Women And The Book Of Mormon: The Creation And Negotiation Of A Latter-Day Saint Tradition, Susanna Morrill

Journal of Book of Mormon Studies

The following article by Susanna Morrill first appeared in Historicizing "Tradition" in the Study of Religion, ed. Steven Engler and Gregory Price Grieve (Berlin: De Gruyter, 2005), 127-44. We believe that it has, unfortunately, not received the attention it deserves for the light it sheds on the ways the Book of Mormon has been received by its readers. Morrill writes from the perspective that the Book of Mormon is a product of the nineteenth-century, but we feel that all stand to learn much from her analysis. We would like to express our gratitude to Professor Morrill, as well as to …

Mormon Scholars And Mormon Families In Family Studies: A Brief Retrospective, David C. Dollahite, Loren D. Marks, Heather Howell Kelley

Mormon Studies Review

No abstract provided.