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Frequency And Isostericity Of Rna Base Pairs, Craig L. Zirbel, Jesse Stombaugh, Eric Westhof Apr 2009

Frequency And Isostericity Of Rna Base Pairs, Craig L. Zirbel, Jesse Stombaugh, Eric Westhof

Chemistry Faculty Publications

Most of the hairpin, internal and junction loops that appear single-stranded in standard RNA secondary structures form recurrent 3D motifs, where non-WatsonCrick base pairs play a central role. Non-WatsonCrick base pairs also play crucial roles in tertiary contacts in structured RNA molecules. We previously classified RNA base pairs geometrically so as to group together those base pairs that are structurally similar (isosteric) and therefore able to substitute for each other by mutation without disrupting the 3D structure. Here, we introduce a quantitative measure of base pair isostericity, the IsoDiscrepancy Index (IDI), to more accurately determine which base pair substitutions can …


The Bg News March 31, 2009, Bowling Green State University Mar 2009

The Bg News March 31, 2009, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. March 31, 2009. Volume 99-Issue 125.


Monitor Newsletter March 30, 2009, Bowling Green State University Mar 2009

Monitor Newsletter March 30, 2009, Bowling Green State University

Monitor

Official Publication of Bowling Green State University for Faculty and Staff


The Bg News March 27, 2009, Bowling Green State University Mar 2009

The Bg News March 27, 2009, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. March 27, 2009. Volume 99-Issue 123.


The Bg News March 25, 2009, Bowling Green State University Mar 2009

The Bg News March 25, 2009, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. March 25, 2009. Volume 99-Issue 121.


Monitor Newsletter March 23, 2009, Bowling Green State University Mar 2009

Monitor Newsletter March 23, 2009, Bowling Green State University

Monitor

Official Publication of Bowling Green State University for Faculty and Staff


The Bg News March 20, 2009, Bowling Green State University Mar 2009

The Bg News March 20, 2009, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. March 20, 2009. Volume 99-Issue 118.


Monitor Newsletter March 16, 2009, Bowling Green State University Mar 2009

Monitor Newsletter March 16, 2009, Bowling Green State University

Monitor

Official Publication of Bowling Green State University for Faculty and Staff


The Bg News March 6, 2009, Bowling Green State University Mar 2009

The Bg News March 6, 2009, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. March 6, 2009. Volume 99-Issue 114.


The Bg News March 4, 2009, Bowling Green State University Mar 2009

The Bg News March 4, 2009, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. March 4, 2009. Volume 99-Issue 112.


The Bg News March 3, 2009, Bowling Green State University Mar 2009

The Bg News March 3, 2009, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. March 3, 2009. Volume 99-Issue 111.


Monitor Newsletter March 02, 2009, Bowling Green State University Mar 2009

Monitor Newsletter March 02, 2009, Bowling Green State University

Monitor

Official Publication of Bowling Green State University for Faculty and Staff


The Bg News March 2, 2009, Bowling Green State University Mar 2009

The Bg News March 2, 2009, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. March 2, 2009. Volume 99-Issue 110.


Board Of Trustees Meeting Minutes 2009-02-27, Bowling Green State University Feb 2009

Board Of Trustees Meeting Minutes 2009-02-27, Bowling Green State University

Board of Trustees Meeting Minutes

The official meeting minutes of Bowling Green State University's Board of Trustees.


The Bg News February 27, 2009, Bowling Green State University Feb 2009

The Bg News February 27, 2009, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. February 27, 2009. Volume 99-Issue 109.


Monitor Newsletter February 23, 2009, Bowling Green State University Feb 2009

Monitor Newsletter February 23, 2009, Bowling Green State University

Monitor

Official Publication of Bowling Green State University for Faculty and Staff


The Bg News February 20, 2009, Bowling Green State University Feb 2009

The Bg News February 20, 2009, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. February 20, 2009. Volume 99-Issue 104.


The Bg News February 17, 2009, Bowling Green State University Feb 2009

The Bg News February 17, 2009, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. February 17, 2009. Volume 99-Issue 101.


The Bg News February 12, 2009, Bowling Green State University Feb 2009

The Bg News February 12, 2009, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. February 12, 2009. Volume 99-Issue 98.


The Bg News February 6, 2009, Bowling Green State University Feb 2009

The Bg News February 6, 2009, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. February 6, 2009. Volume 99-Issue 94.


Monitor Newsletter February 02, 2009, Bowling Green State University Feb 2009

Monitor Newsletter February 02, 2009, Bowling Green State University

Monitor

Official Publication of Bowling Green State University for Faculty and Staff


Probing Single-Molecule Interfacial Electron Transfer Dynamics Of Porphyrin On Tio2 Nanoparticles, Yuanmin Wang, Xuefei Wang, Sujit Kumar Ghosh, H. Peter Lu Feb 2009

Probing Single-Molecule Interfacial Electron Transfer Dynamics Of Porphyrin On Tio2 Nanoparticles, Yuanmin Wang, Xuefei Wang, Sujit Kumar Ghosh, H. Peter Lu

Chemistry Faculty Publications

Single-molecule interfacial electron transfer (ET) dynamics has been studied by using single-molecule fluorescence spectroscopy and microscopic imaging. For a single-molecule zinc-tetra (4-carboxyphenyl) porphyrin (ZnTCPP)/TiO2 nanoparticle system, the single-molecule fluorescence trajectories show strong fluctuation and blinking between bright and dark states. The intermittency and fluctuation of the single-molecule fluorescence are attributed to the variation of the reactivity of interfacial electron transfer. The nonexponential autocorrelation function and the power-law distribution of the probability density of dark times imply the dynamic and static inhomogeneities of the interfacial ET dynamics. On the basis of the power-law analysis, the variation of single-molecule interfacial ET reactivity …


The Bg News January 30, 2009, Bowling Green State University Jan 2009

The Bg News January 30, 2009, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. January 30, 2009. Volume 99-Issue 89.


The Bg News January 28, 2009, Bowling Green State University Jan 2009

The Bg News January 28, 2009, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. January 28, 2009. Volume 99-Issue 87.


Monitor Newsletter January 26, 2009, Bowling Green State University Jan 2009

Monitor Newsletter January 26, 2009, Bowling Green State University

Monitor

Official Publication of Bowling Green State University for Faculty and Staff


Monitor Newsletter January 20, 2009, Bowling Green State University Jan 2009

Monitor Newsletter January 20, 2009, Bowling Green State University

Monitor

Official Publication of Bowling Green State University for Faculty and Staff


The Bg News January 15, 2009, Bowling Green State University Jan 2009

The Bg News January 15, 2009, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. January 15, 2009. Volume 99-Issue 79.


The Bg News January 14, 2009, Bowling Green State University Jan 2009

The Bg News January 14, 2009, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. January 14, 2009. Volume 99-Issue 78.


The Bg News January 13, 2009, Bowling Green State University Jan 2009

The Bg News January 13, 2009, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. January 13, 2009. Volume 99-Issue 77.


Monitor Newsletter January 12, 2009, Bowling Green State University Jan 2009

Monitor Newsletter January 12, 2009, Bowling Green State University

Monitor

Official Publication of Bowling Green State University for Faculty and Staff