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Articles 301 - 330 of 2020
Full-Text Articles in Entire DC Network
"Women Are Again Unsafe": Preventing Violence And Poor Maternal Outcomes During Current Floods In Pakistan, Sarmad Muhammad Soomar, Abir Arefin, Salman Muhammad Soomar
"Women Are Again Unsafe": Preventing Violence And Poor Maternal Outcomes During Current Floods In Pakistan, Sarmad Muhammad Soomar, Abir Arefin, Salman Muhammad Soomar
School of Nursing & Midwifery
No abstract provided.
Impact Of Enteropathogens On Faltering Growth In A Resource-Limited Setting, Furqan Kabir, Junaid Iqbal, Zehra Jamil, Najeeha Talat Iqbal, Fatima Aziz, Adil Kalam, Sahrish Muneer, Aneeta Hotwani, Sheraz Ahmed, Fayyaz Umrani, Sana Syed, Kamran Sadiq, Syed Asad Ali
Impact Of Enteropathogens On Faltering Growth In A Resource-Limited Setting, Furqan Kabir, Junaid Iqbal, Zehra Jamil, Najeeha Talat Iqbal, Fatima Aziz, Adil Kalam, Sahrish Muneer, Aneeta Hotwani, Sheraz Ahmed, Fayyaz Umrani, Sana Syed, Kamran Sadiq, Syed Asad Ali
Department of Paediatrics and Child Health
Introduction: Environmental enteropathy is an important contributor to childhood malnutrition in the developing world. Chronic exposure to fecal pathogens leads to alteration in intestinal structure and function, resulting in impaired gut immune function, malabsorption, and growth faltering leading to environmental enteropathy.
Methods: A community-based intervention study was carried out on children till 24 months of age in Matiari district, Pakistan. Blood and fecal specimens were collected from the enrolled children aged 3-6 and 9 months. A real-time PCR-based TaqMan array card (TAC) was used to detect enteropathogens.
Results: Giardia, Campylobacter spp., enteroaggregative Escherichia coli (EAEC), Enteropathogenic Escherichia coli (EPEC), …
Family Income And Cardiovascular Disease Risk In American Adults, Abdul Mannan Khan Minhas, Vardhmaan Jain, Monica Li, Robert W. Ariss, Marat Fudim, Erin D. Michos, Salim S. Virani, Laurence Sperling, Anurag Mehta
Family Income And Cardiovascular Disease Risk In American Adults, Abdul Mannan Khan Minhas, Vardhmaan Jain, Monica Li, Robert W. Ariss, Marat Fudim, Erin D. Michos, Salim S. Virani, Laurence Sperling, Anurag Mehta
Office of the Provost
Socioeconomic status is an overlooked risk factor for cardiovascular disease (CVD). Low family income is a measure of socioeconomic status and may portend greater CVD risk. Therefore, we assessed the association of family income with cardiovascular risk factor and disease burden in American adults. This retrospective analysis included data from participants aged ≥ 20 years from the National Health and Nutrition Examination Survey (NHANES) cycles between 2005 and 2018. Family income to poverty ratio (PIR) was calculated by dividing family (or individual) income by poverty guidelines specific to the survey year and used as a measure of socioeconomic status. The …
Metabolomics Of A Neonatal Cohort From The Alliance For Maternal And Newborn Health Improvement Biorepository: Effect Of Preanalytical Variables On Reference Intervals, Lena Jafri, Aysha Habib Khan, Muhammad Ilyas, Muhammad Imran Nisar, Javairia Khalid, Hafsa Majid, Aneeta Hotwani, Fyezah Jehan
Metabolomics Of A Neonatal Cohort From The Alliance For Maternal And Newborn Health Improvement Biorepository: Effect Of Preanalytical Variables On Reference Intervals, Lena Jafri, Aysha Habib Khan, Muhammad Ilyas, Muhammad Imran Nisar, Javairia Khalid, Hafsa Majid, Aneeta Hotwani, Fyezah Jehan
Department of Pathology and Laboratory Medicine
Background: The study was conducted to determine reference interval (RI) and evaluate the effect of preanalytical variables on Dried blood spot (DBS)-amino acids, acylcarnitines and succinylacetone of neonates.
Methodology: DBS samples were collected within 48-72 hours of life. Samples were analyzed for biochemical markers on tandem mass spectrometer at the University of Iowa. Comparison of RI across various categorical variables were performed.
Results: A total of 610 reference samples were selected based on exclusion criteria; 53.2% being females. Mean gestational age (GA) of mothers at the time of delivery was 38.7±1.6 weeks; 24.5% neonates were of low birth weight and …
Concept Of Health-Related Quality Of Life Among People With Heart Failure In Karachi, Pakistan, Anny Ashiq Ali
Concept Of Health-Related Quality Of Life Among People With Heart Failure In Karachi, Pakistan, Anny Ashiq Ali
MBE 2023
Background: Non-communicable diseases (NCDs), including cardiovascular diseases, are a leading cause of global mortality. The mortality rate for cardiovascular diseases is on the rise, with 80 % to 86 % of fatalities, particularly in low- and middle-income countries, including Pakistan. Among NCDs, heart failure (HF) is a condition for which there is no cure, and patients rely on supportive treatments to maintain their quality of life. HF not only affects physical well-being but also has far-reaching consequences on the emotional, social, and cognitive aspects of life. In the context of Pakistan, where unique healthcare, sociocultural, and economic factors prevail, the …
Health-Related Quality Of Life Of Children With Gastro-Oesophageal Reflux Disease After Nissen Fundoplication And Gastrostomy Tube Insertion, Felix Musibi, Stanley Mugambi, Pauline Samia, Waceke Nganga
Health-Related Quality Of Life Of Children With Gastro-Oesophageal Reflux Disease After Nissen Fundoplication And Gastrostomy Tube Insertion, Felix Musibi, Stanley Mugambi, Pauline Samia, Waceke Nganga
Paediatrics and Child Health, East Africa
Introduction: Severe gastro‑oesophageal reflux disease (GERD) is associated with a poor health‑related quality of life (HRQoL). Nissen fundoplication is the most common surgical procedure for patients with GERD. A feeding gastrostomy tube may be inserted at the same time in selected patients where there are unsafe swallowing and/or feeding difficulties. The goals of surgery are to eliminate symptoms, prevent reflux complications and ultimately improve the quality of life. The main objective of this study was to assess the HRQoL of children with GERD after Nissen fundoplication and gastrostomy tube insertion.
Materials and Methods: This was an observational retrospective cohort study …
Smallholder Views On Chinese Agricultural Investments In Mozambique And Tanzania In The Context Of Vggts, Rebecca Pointer, Emmanuel Sulle, Clemente Ntauazi
Smallholder Views On Chinese Agricultural Investments In Mozambique And Tanzania In The Context Of Vggts, Rebecca Pointer, Emmanuel Sulle, Clemente Ntauazi
East Africa Institute
Based on a case study in each country, this study documents the views of Mozambican and Tanzanian smallholders regarding Chinese agricultural investments and the extent to which investors abide by their legitimate land tenure rights as defined by the Voluntary Guidelines for the Responsible Governance of Tenure of Land, Forests and Fisheries in the Context of National Food Security (VGGTs). The VGGTs offer guidelines to government on how to protect the land tenure of rural communities when land is being acquired for large-scale land investments. The study also assessed the impact of the COVID-19 pandemic on smallholders. Due to COVID-19, …
Current Status And Priorities Of Paediatric Oncology Nursing In Africa: A Synthesis Of Perspectives From Siop Africa Nurses, Glenn M. Afungchwi, Elianeth Kiteni, Mariam Ndagire, Biemba Maliti, Julia M. Challinor, Rachel Hollis
Current Status And Priorities Of Paediatric Oncology Nursing In Africa: A Synthesis Of Perspectives From Siop Africa Nurses, Glenn M. Afungchwi, Elianeth Kiteni, Mariam Ndagire, Biemba Maliti, Julia M. Challinor, Rachel Hollis
School of Nursing & Midwifery, East Africa
Introduction. As African countries adopt the global goal of improving childhood cancer survival to 60% by 2030, intentional actions are required to improve nursing. This report aims to describe the current status of paediatric oncology nursing in Africa.
Methods. We report on nursing-related aspects of a survey to map paediatric oncology services in Africa (2018–2019), document perceived nursing strengths and weaknesses (2017) and share nurses’ research priorities (2019). Additionally, we report on a survey to identify topics for a foundation course (2019) and the expressed perspective of African nurses about the status of paediatric oncology nursing across the continent (2022). …
Exploration Of Factors Contributing To Low Achievement Of Learners In Chemistry At Ordinary Secondary Level. A Case Study Of A Mixed Secondary School In Katrini Sub-County, Terego District, Uganda., Andrew Ababo
Master of Education
The performance of learners in the ordinary secondary section has been low over the years in Uganda. Many learners fail to pass chemistry at ordinary secondary level as such, very few students offer the subject at higher levels. The general purpose of this study was to explore factors contributing to low achievement of learners in chemistry at ordinary secondary section in a mixed secondary school in Katrini sub-county, Terego district, Uganda. A qualitative research approach with a case study design was applied. The sample size had twenty-two participants made up of ten females and twelve males in the following categories: …
Factors That Influence Girl Child Performance In Science In Upper Primary Classes: A Case Of Two Selected Primary Schools In Arua District, Uganda., Ajuko Anna Grace
Factors That Influence Girl Child Performance In Science In Upper Primary Classes: A Case Of Two Selected Primary Schools In Arua District, Uganda., Ajuko Anna Grace
Master of Education
This study explored the factors that influence girl child performance in integrated science in upper primary classesin two primary schools in Arua district, Uganda. The findings are reflected in the themes; how girls perform in integrated science, factors that influence girls’ performance and strategies that can be used to improve girls’ performance in integrated science in primary schools. This study embraced a qualitative research approach and a case study design. The study sample comprised of thirty (30) participants which included two head teachers from the two selected primary schools, four teachers of science two from each school of study who …
Views And Opinions Of Mass Media Key Informants On Coverage Of Issues Related To Maternal, Newborn And Child Health In Lake Zone, Tanzania, Violeth A. Mbuni, Nyagwegwe Wango, Elias C. Nyanza
Views And Opinions Of Mass Media Key Informants On Coverage Of Issues Related To Maternal, Newborn And Child Health In Lake Zone, Tanzania, Violeth A. Mbuni, Nyagwegwe Wango, Elias C. Nyanza
Institute for Educational Development, East Africa
In Tanzania, the mass media is a primary means of communicating health information to urban and rural populations. While unsafe abortion is the leading cause of maternal deaths and complications in Tanzania, this has increased the high unintended pregnancy rate. Journalists, editors, program managers and producers play a significant role in determining the health-related issues reported. In the present study, the views, and opinions of mass media key informants on coverage of issues related to maternal, newborn and child health in Lake Zone were investigated. This qualitative study was conducted with key informants from 24 mass media outlets that covered …
Relationship Between Crown Like Structures And Body Mass Index In Breast Cancer, Sophie Wanjiru Irungu
Relationship Between Crown Like Structures And Body Mass Index In Breast Cancer, Sophie Wanjiru Irungu
Master of Medicine in Anatomic Pathology
Introduction: Breast cancer (BC) is the most common malignancy in women worldwide, including Kenya. Globally, increasing incidences of BC have paralleled those of obesity. The mechanism by which obesity contributes to BC is still an active area of research but white adipose tissue inflammation characterized by crown-like structures (CLS), which are macrophages surrounding dying adipocytes, is considered an important contributor. Objectives: The primary objective was to determine the association between CLS and body mass index (BMI) in BC patients. The secondary objectives were to determine the association of CLS with BC risk factors specifically, age, menopausal status, subtypes of BC, …
Assessment Of The Knowledge, Attitude, And Practice Of Postoperative Pain Management Among Nurses In Medical And Surgical Wards At Aga Khan University Hospital, Veronicah Wangui
Assessment Of The Knowledge, Attitude, And Practice Of Postoperative Pain Management Among Nurses In Medical And Surgical Wards At Aga Khan University Hospital, Veronicah Wangui
MSc in Advanced Practice Nursing
Postoperative pain remains a significant global problem despite overall pain management advances. Postoperative pain may alter neural pathophysiology, including peripheral and central sensation, and lead to chronic pain syndrome. Postoperative pain management implies professional care to improve patients’ comfort and early ambulation, decrease analgesia side effects, and reduce chronic pain. Nurses taking care of postoperative patients must be equipped with adequate knowledge and skills to be effective. This study aimed to assess the knowledge, attitude, and nurses' practice on postoperative pain management among nurses in medico-surgical wards at Aga Khan University Hospital. It is a quantitative descriptive cross-sectional study. Data …
Examining The Management Of Second Chance Schools: A Case Study Of Secondary School For Teen Mothers In Kenya, Nancy Chebet
Examining The Management Of Second Chance Schools: A Case Study Of Secondary School For Teen Mothers In Kenya, Nancy Chebet
Master of Education
Teen pregnancy in Kenya is on the increase and is widely attributed to the prolonged closure of schools because of the COVID-19 pandemic, and widespread exposure to irresponsible sexual behaviours and exploitation. Approximately 13,000 girls dropped out of school in 2021 due to teenage pregnancies. However, since children command the right to education and education is a priority in sustainable development goals, the feminist movement has established ways to ensure teen mothers are educated, in Kenya, there is the rise of schools designated for teen mothers. Therefore, the study sought to examine how these schools are managed this is because …
Effectiveness Of An Integrated Multilevel Early Child Development Intervention On Caregiver Knowledge And Behavior: A Quasi-Experimental Evaluation Of The Malezi Program In Tanzania, Gretchen Antelman, Josephine Ferla, Michelle M. Gill, Heather J. Hoffman, Teopista Komba, Amina Abubakar, Pieter Remes, Ola Jahanpour, Martha Mariki, Mary A. Mang’Enya, Roland Van De Ven
Effectiveness Of An Integrated Multilevel Early Child Development Intervention On Caregiver Knowledge And Behavior: A Quasi-Experimental Evaluation Of The Malezi Program In Tanzania, Gretchen Antelman, Josephine Ferla, Michelle M. Gill, Heather J. Hoffman, Teopista Komba, Amina Abubakar, Pieter Remes, Ola Jahanpour, Martha Mariki, Mary A. Mang’Enya, Roland Van De Ven
Institute for Human Development, East Africa
Background The quality of caregiving and the parent-child relationship is critical for early child development (ECD) and has been shown to be modifiable. This study evaluated an ECD project in Tanzania, assessing the effectiveness of radio messaging (RM) alone and a combined radio messaging/video job aids/ECD (RMV-ECD) intervention.
Methods This two-arm pre-post evaluation study enrolled a cohort of caregivers of children 0–24 months in four districts of Tabora region, following them for 9 months. ECD radio messages were broadcast on popular stations at least 10 times/day reaching all study districts. In two districts, community health workers (CHW), trained in UNICEF’s …
Country Readiness And Prerequisites For Successful Design And Transition To Implementation Of Essential Packages Of Health Services: Experience From Six Countries, Ala Alwan, Reza Majdzadeh, Gavin Yamey, Karl Blanchet, Alemayehu Hailu, Mohamed Jama, Kjell Arne Johansson, Mohammed Yusuf Ahmed Musa, Omar Mwalim, Sameen Siddiqi
Country Readiness And Prerequisites For Successful Design And Transition To Implementation Of Essential Packages Of Health Services: Experience From Six Countries, Ala Alwan, Reza Majdzadeh, Gavin Yamey, Karl Blanchet, Alemayehu Hailu, Mohamed Jama, Kjell Arne Johansson, Mohammed Yusuf Ahmed Musa, Omar Mwalim, Sameen Siddiqi
Community Health Sciences
This paper reviews the experience of six low-income and lower middle-income countries in setting their own essential packages of health services (EPHS), with the purpose of identifying the key requirements for the successful design and transition to implementation of the packages in the context of accelerating progress towards universal health coverage (UHC). The analysis is based on input from three meetings of a knowledge network established by the Disease Control Priorities 3 Country Translation Project and working groups, supplemented by a survey of participating countries. All countries endorsed the Sustainable Development Goals target 3.8 on UHC for achievement by 2030. …
Why Skin-To-Skin Contact Is Not Made A Traditional Practice Right After Childbirth? Hindrances Behind Its Non-Implementation, Ateefa Al-Noor
Why Skin-To-Skin Contact Is Not Made A Traditional Practice Right After Childbirth? Hindrances Behind Its Non-Implementation, Ateefa Al-Noor
Journal of Asian Midwives (JAM)
Skin-to-skin contact (SSC) is the practice in which a newborn is dried and placed immediately on mother’s chest. Both the mother and the baby gains benefits from this as it aids in breastfeeding and helps baby adjust to temperature outside the mother’s womb. However, not many midwives in hospitals carry out this crucial practice. Staff shortage, lack of awareness and time constraints were identified as the main determinants because SSC was not implemented. Realistic measures should be taken to enhance SSC as discussed in the paper. Thus, promotion of SSC soon after childbirth will be advantageous for neonatal quality of …
The Impact And Outcomes Of Sustainable Intensification Initiatives In Six Countries On Women, Men, And Other Social Groups, Katherine A. Snyder, Emanuel Sulle
The Impact And Outcomes Of Sustainable Intensification Initiatives In Six Countries On Women, Men, And Other Social Groups, Katherine A. Snyder, Emanuel Sulle
East Africa Institute
This study reviewed over 160 papers and reports in sustainable intensification, with a focus on the target countries of Malawi, Ghana, Ethiopia, Laos, Bangladesh and Nepal. It collected literature by carrying out searched with both scopus and google scholar with specific key words and combinations. This search focused on target regions and countries as well as social equity. Under “sustainable intensification”, we obtained a list of 5493 papers. Sustainable intensification and gender yielded 58, SI in Sub-Saharan Africa produced 545. Country by country the papers were fewer and when gender and social equity were included, the number of papers were …
Labrad : Vol 47, Issue 2 - December 2022, Aga Khan University Hospital, Karachi
Labrad : Vol 47, Issue 2 - December 2022, Aga Khan University Hospital, Karachi
LABRAD - Departments of Pathology & Laboratory Medicine and Radiology Archives
- From the Editor’s Desk
- Case Quiz
- Contrast Enhanced Spectral Mammography Clinical Usefulness of Biochemical Parameters in Prenatal Diagnosis of Down Syndrome In First and Second Trimester
- The Science of Efficiency in a Clinical Laboratory
- Updates in new WHO Blue Book
- Monkeypox vs. COVID-19
- From the Diary of a Researcher- Notes on Understanding Beta-Thalassemia and Metabolic Bone Disease
- Significance of Audit in a Clinical Laboratory
- Microsatellite Instability (MSI) Testing
- Pre-Analytical Variables Affecting Coagulation Testing
- Grading of Soft Tissue Sarcomas
- Recent Updates in 2022 WHO Classification of Thyroid Neoplasms
- MMR and MSI Testing in Malignancies
- Transforming Pedagogical Framework of Pathology through Social …
Perpetuation Of Gender Discrimination In Pakistani Society: Results From A Scoping Review And Qualitative Study Conducted In Three Provinces Of Pakistan, Tazeen Saeed Ali, Shahnaz Shahid Ali, Sanober Nadeem, Zahid Memon, Sajid Bashir Soofi, Falak Madhani, Yasmin Karim, Shah Mohammad, Zulfiqar Ahmed Bhutta
Perpetuation Of Gender Discrimination In Pakistani Society: Results From A Scoping Review And Qualitative Study Conducted In Three Provinces Of Pakistan, Tazeen Saeed Ali, Shahnaz Shahid Ali, Sanober Nadeem, Zahid Memon, Sajid Bashir Soofi, Falak Madhani, Yasmin Karim, Shah Mohammad, Zulfiqar Ahmed Bhutta
School of Nursing & Midwifery
Background: Gender discrimination is any unequal treatment of a person based on their sex. Women and girls are most likely to experience the negative impact of gender discrimination. The aim of this study is to assess the factors that influence gender discrimination in Pakistan, and its impact on women's life.
Methods: A mixed method approach was used in the study in which a systematic review was done in phase one to explore the themes on gender discrimination, and qualitative interviews were conducted in phase two to explore the perception of people regarding gender discrimination. The qualitative interviews (in-depth interviews and …
Experiences Of Mothers And Significant Others In Accessing Comprehensive Healthcare In The First 1000 Days Of Life Post-Conception During Covid-19 In Rural Uganda, Grace Nakate, Sean Mackay, Eunice Ndirangu, Valerie Fleming
Experiences Of Mothers And Significant Others In Accessing Comprehensive Healthcare In The First 1000 Days Of Life Post-Conception During Covid-19 In Rural Uganda, Grace Nakate, Sean Mackay, Eunice Ndirangu, Valerie Fleming
School of Nursing & Midwifery, East Africa
Background: COVID-19 presented an unprecedented global public health challenge because of its rapid and relentless spread, and many countries instituted lockdowns to prevent the spread of infection. Although this strategy mayhave been appropriate to reduce infection, it presented unintended difficulties in rural Uganda, especially in maternal and born newborn care. For example, some services were suspended, meaning the nearest health facility was at a considerable distance. This study explored the experiences of mothers and their significant others of comprehensive care in the first 1000 days of life post-conception during the COVID-19 pandemic in Bunghokho-Mutoto sub-county, Mbale District, Uganda.
Methods …
Cultural And Contextual Adaptation Of Mental Health Measures In Kenya: An Adolescent-Centered Transcultural Adaptation Of Measures Study, Vincent Nyongesa, Shillah Mwaniga, Joseph Kathono, Obadia Yator, Beatrice Madeghe, Sarah Kanana, Beatrice Amugune, Naomi Anyango, Darius Nyamai, Manasi Kumar
Cultural And Contextual Adaptation Of Mental Health Measures In Kenya: An Adolescent-Centered Transcultural Adaptation Of Measures Study, Vincent Nyongesa, Shillah Mwaniga, Joseph Kathono, Obadia Yator, Beatrice Madeghe, Sarah Kanana, Beatrice Amugune, Naomi Anyango, Darius Nyamai, Manasi Kumar
Brain and Mind Institute
Introduction: There is paucity of culturally adapted tools for assessing depression and anxiety in children and adolescents in low-and middle-income countries. This hinders early detection, provision of appropriate and culturally acceptable interventions. In a partnership with the University of Nairobi, Nairobi County, Kenyatta National Hospital, and UNICEF, a rapid cultural adaptation of three adolescent mental health scales was done, i.e., Revised Children’s Anxiety and Depression Scale, Patient Health Questionnaire-9 and additional scales in the UNICEF mental health module for adolescents.
Materials and methods: Using a qualitative approach, we explored adolescent participants’ views on cultural acceptability, comprehensibility, relevance, and completeness of …
The Sub-Standardized Approach To Stroke Management In Low And Middle-Income Countries Including Pakistan: Limitations And Suggested Options To Overcome Some Of The Shortcomings Via Teleneurology/Telestroke Application, Rizwana Shahid
Pakistan Journal of Neurological Sciences (PJNS)
Background and objective: Ischemic stroke still poses a significant health concern throughout the world. However, low and middle-income countries (LMIC) in Asia have more devastating outcome. The vascular risk factors are prevalent in most parts of Asia, contributing to increasing incidence. The recommended approved treatment for acute stroke is limited to a few areas in these countries. We aimed to identify stroke risk factors, its incidence and prevalence; treatment opportunities offered in various parts of the region and utilizing the alternate pathways to improve the disease recognition and management outcome.
Method: A comprehensive search using PubMed, MEDLINE, Medline Plus, PubMed …
Cost Utility Of Supporting Family-Based Care To Prevent Hiv And Deaths Among Orphaned And Separated Children In East Africa: A Markov Model–Based Simulation, Marta Wilson-Barthes, Paula Braitstein, Allison Delong, David Ayuku, Lukoye Atwoli, Edwin Sang, Omar Galárraga
Cost Utility Of Supporting Family-Based Care To Prevent Hiv And Deaths Among Orphaned And Separated Children In East Africa: A Markov Model–Based Simulation, Marta Wilson-Barthes, Paula Braitstein, Allison Delong, David Ayuku, Lukoye Atwoli, Edwin Sang, Omar Galárraga
Internal Medicine, East Africa
Purpose: Strengthening family-based care is a key policy response to the more than 15 million orphaned and separated children who have lost 1 or both parents in sub-Saharan Africa. This analysis estimated the cost-effectiveness of family-based care environments for preventing HIV and death in this population.
Design: We developed a time-homogeneous Markov model to simulate the incremental cost per disability-adjusted life year (DALY) averted by supporting family-based environments caring for orphaned and separated children in western Kenya. Model parameters were based on data from the longitudinal OSCAR’s Health and Well-Being Project and published literature. We used a societal perspective, …
Secondhand Smoke Exposure Is Independently Associated With Stroke Among Non-Smoking Adults In West Africa., Akinkunmi Paul Okekunle, Osahon Jeffery Asowata, Adekunle G. Fakunle, Onoja Matthew Akpa, Fred S. Sarfo, Albert Akpalu, Kolawole Wahab, Reginald Obiako, Morenikeji Komolafe, Philip Adebayo
Secondhand Smoke Exposure Is Independently Associated With Stroke Among Non-Smoking Adults In West Africa., Akinkunmi Paul Okekunle, Osahon Jeffery Asowata, Adekunle G. Fakunle, Onoja Matthew Akpa, Fred S. Sarfo, Albert Akpalu, Kolawole Wahab, Reginald Obiako, Morenikeji Komolafe, Philip Adebayo
Internal Medicine, East Africa
Background: Stroke is a leading cause of disability and mortality worldwide, but little is known about the contribution of secondhand smoke exposure (SHSE) to stroke epidemiology among indigenous Africans.
Objective: To evaluate the association of SHSE with stroke among indigenous Africans. Methods We analyzed the relationship of SHSE with stroke among 2990 case-control pairs of adults who had never smoked (identified in the SIREN study) using conditional logistic regression at a two-sided P < 0.05.
Results: Multivariable-adjusted odds ratio and 95% confidence interval; 1.25 (1.04, 1.50; P = 0.02) revealed SHSE was positively associated with stroke independent of stroke subtypes.
Conclusion: …
Pregnancy And Childbirth: Male Partner Involvement In Uasin Gishu, Kenya, Kamau Tabitha, Roselyter Riang’A, Mwanzia Lydia, Buluku Elizabeth, Sawe Caroline, Wambugu Beth, Patel Kirtika, Mutai Judith, Pauline Mwenje, Kemboi Sharon
Pregnancy And Childbirth: Male Partner Involvement In Uasin Gishu, Kenya, Kamau Tabitha, Roselyter Riang’A, Mwanzia Lydia, Buluku Elizabeth, Sawe Caroline, Wambugu Beth, Patel Kirtika, Mutai Judith, Pauline Mwenje, Kemboi Sharon
Population Health, East Africa
Introduction: In many African countries, pregnancy and childbirth has traditionally beenregarded as a woman’s affair. As a result, male partner involvement and participationin pregnancy and childbirth has been minimal, which is thought to have contributed tothe high rate of maternal and neonatal morbidities and mortalities. Male partners areoften key decision-makers in African households for cultural reasons, yet their role inpregnancy and childbirth is not clearly defined. The aim of this study was to examine anddocument male partner involvement in maternal healthcare in Kenya.
Methods: A health facility-based cross-sectional descriptive study design was used.Systematic random sampling was used to …
Immunity To Poliovirus In Afghanistan: A Household Sampling Method For Serological Assessment Based On Geographical Information Systems, Amalia Mendes, Ari Whiteman, Benjamin Nygren, Brian Kaplan, Imtiaz Hussain, Sajid Bashir Soofi, Maureen Martinez, Noha H. Farag
Immunity To Poliovirus In Afghanistan: A Household Sampling Method For Serological Assessment Based On Geographical Information Systems, Amalia Mendes, Ari Whiteman, Benjamin Nygren, Brian Kaplan, Imtiaz Hussain, Sajid Bashir Soofi, Maureen Martinez, Noha H. Farag
Department of Paediatrics and Child Health
Afghanistan continues to experience challenges affecting polio eradication. Mass polio vaccination campaigns, which aim to protect children under the age of 5, are a key eradication strategy. To date, the polio program in Afghanistan has only employed facility-based seroprevalence surveys, which can be subject to sampling bias. We describe the feasibility in implementing a cross-sectional household poliovirus seroprevalence survey based on geographical information systems (GIS) in three districts. Digital maps with randomly selected predetermined starting points were provided to teams, with a total target of 1,632 households. Teams were instructed to navigate to predetermined starting points and enrol the closest …
The Childhood Acute Illness And Nutrition (Chain) Network Nested Case-Cohort Study Protocol: A Multi-Omics Approach To Understanding Mortality Among Children In Sub-Saharan Africa And South Asia, James M. Njunge, Kirkby Tickell, Abdoulaye Hama Diallo, Abu Sadat Mohammad Sayeem Bin Shahi, Md Amran Gazi, Ali Faisal Saleem, Zaubina Kazi, Syed Ali, Caroline Tigoi, Ezekiel Mupere
The Childhood Acute Illness And Nutrition (Chain) Network Nested Case-Cohort Study Protocol: A Multi-Omics Approach To Understanding Mortality Among Children In Sub-Saharan Africa And South Asia, James M. Njunge, Kirkby Tickell, Abdoulaye Hama Diallo, Abu Sadat Mohammad Sayeem Bin Shahi, Md Amran Gazi, Ali Faisal Saleem, Zaubina Kazi, Syed Ali, Caroline Tigoi, Ezekiel Mupere
Department of Paediatrics and Child Health
Introduction: Many acutely ill children in low- and middle-income settings have a high risk of mortality both during and after hospitalisation despite guideline-based care. Understanding the biological mechanisms underpinning mortality may suggest optimal pathways to target for interventions to further reduce mortality. The Childhood Acute Illness and Nutrition (CHAIN) Network ( www.chainnnetwork.org) Nested Case-Cohort Study (CNCC) aims to investigate biological mechanisms leading to inpatient and post-discharge mortality through an integrated multi-omic approach.
Methods and analysis; The CNCC comprises a subset of participants from the CHAIN cohort (1278/3101 hospitalised participants, including 350 children who died and 658 survivors, and …
Risk Factors For Community-Acquired Bacterial Infection Among Young Infants In South Asia: A Longitudinal Cohort Study With Nested Case–Control Analysis, Nicholas E. Connor, Mohammad Shahidul Islam, Luke C. Mullany, Nong Shang, Zulfiqar Ahmed Bhutta, Anita K. M. Zaidi, Sajid Bashir Soofi, Muhammad Imran Nisar, Pinaki Panigrahi, Kalpana Panigrahi
Risk Factors For Community-Acquired Bacterial Infection Among Young Infants In South Asia: A Longitudinal Cohort Study With Nested Case–Control Analysis, Nicholas E. Connor, Mohammad Shahidul Islam, Luke C. Mullany, Nong Shang, Zulfiqar Ahmed Bhutta, Anita K. M. Zaidi, Sajid Bashir Soofi, Muhammad Imran Nisar, Pinaki Panigrahi, Kalpana Panigrahi
Department of Paediatrics and Child Health
Objective: Risk factors predisposing infants to community-acquired bacterial infections during the first 2 months of life are poorly understood in South Asia. Identifying risk factors for infection could lead to improved preventive measures and antibiotic stewardship.
Methods: Five sites in Bangladesh, India and Pakistan enrolled mother-child pairs via population-based pregnancy surveillance by community health workers. Medical, sociodemographic and epidemiological risk factor data were collected. Young infants aged 0-59 days with signs of possible serious bacterial infection (pSBI) and age-matched controls provided blood and respiratory specimens that were analysed by blood culture and real-time PCR. These tests were used to build …
Research Attitudes, Practice And Literacy Among Kenyan Palliative Care Healthcare Professionals: An Observational, Crosssectional Online Survey, Ra Powell, Z Ali, Nancy Gikaara, Qanungo S, Es Melikam, Kb Cartmell
Research Attitudes, Practice And Literacy Among Kenyan Palliative Care Healthcare Professionals: An Observational, Crosssectional Online Survey, Ra Powell, Z Ali, Nancy Gikaara, Qanungo S, Es Melikam, Kb Cartmell
Internal Medicine, East Africa
Background: While research is needed to advocate for implementation of global agendas to strengthen palliative care, healthcare professionals’ research literacy must improve to bridge the gap between evidence and practice. A resurgent focus on North-South power disparities, means attention should also focus on understanding low- and middle-income countries’ local agency to implement palliative care research agendas.
Methods: An observational, cross-sectional online survey among Kenyan palliative healthcare professionals currently working at any of the palliative and hospice care organizations operational during January – December 2019, using descriptive statistics.
Results: Among the 93 survey respondents, participants were mainly nurses (50.54%; n=47). Regarding …