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Responselockr: An Open Source Erp Analysis Toolkit, Angie Georgaras Apr 2020

Responselockr: An Open Source Erp Analysis Toolkit, Angie Georgaras

Undergraduate Research and Engagement Symposium

Current ERP analysis tools are insufficient in that they do not allow users to calculate ERPs time locked to the participant's response. They are also limited in the kinds of data visualizations and advanced statistical calculations available. Thus, we created our own open-source tool in R, an open-source programming language designed for statistics and visualization. Our tool, ResponseLockR, can calculate response-locked ERPs baseline correcting them to the pre-stimulus baseline. Our tool will also allow us to use a variety of robust statistical procedures (multilevel modeling, structural equation modeling) not commonly offered in other statistical software.

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Title: The Effect Of Curcumin On The Human Gut Epithelium And Resident Microbiota, Vraj Patel Apr 2020

Title: The Effect Of Curcumin On The Human Gut Epithelium And Resident Microbiota, Vraj Patel

Undergraduate Research and Engagement Symposium

The microbiome is a dynamic ecosystem with multiple regulatory properties that influence physiological responses. We hypothesize that curcumin, a bioactive component in turmeric known for its antitumor and anti-inflammatory properties, influences changes in the gut identity which leads to the beneficial effects. However, the microbiome does not exist in isolation and is constantly interacting with and influencing the adjacent epithelial cells and the body as a whole. We will also be observing the changes in the cells’ proliferation and movement of the intestinal epithelial cells.

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A Review Of Quinolone Antimalarials, Miriam Velazquez Apr 2020

A Review Of Quinolone Antimalarials, Miriam Velazquez

Undergraduate Research and Engagement Symposium

Malaria affects millions of people worldwide. Resistance to drugs that treat malaria has increased the demand for efficient drugs. The search for antimalarial drugs has led to the synthesis of a vast number of quinolone analogues as potential antimalarials. An important tool for medicinal chemists in discovering new treatments for diseases is recognizing structure activity relationships.

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Interactions Between Microplastic Fibers, Microbial Communities, And Triclosan In Freshwater Streams, Masooma Sultan, Astha Chokshi Apr 2020

Interactions Between Microplastic Fibers, Microbial Communities, And Triclosan In Freshwater Streams, Masooma Sultan, Astha Chokshi

Undergraduate Research and Engagement Symposium

The effects of adsorbed POPs and bacterial communities colonizing microplastic surfaces were studied. Triclosan, a common anti-microbial compound which serves as an organic pollutant in the environment was investigated in relation with fibers made in the lab (acrylic and polyester) as a follow-up to a recent experiment done in this lab. This studied the particular interaction between triclosan, the microplastic fibers, and microbial communities to come to a conclusion of what led to a decrease in triclosan. Also including if the adsorption of POPs to microplastic with microbial communities has particular effects that may lead to a decrease in triclosan.

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A Series Of 4- And 5-Coordinate Nickel Compounds, Andrew Karafa Apr 2020

A Series Of 4- And 5-Coordinate Nickel Compounds, Andrew Karafa

Undergraduate Research and Engagement Symposium

My presentation shows off the continued research into a series of Nickel complexes synthesized using a specially designed Lee Lab ligand.

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Autonomy And Addiction And What It Means For The Rest Of Us, Aaliyah Sevier Apr 2020

Autonomy And Addiction And What It Means For The Rest Of Us, Aaliyah Sevier

Undergraduate Research and Engagement Symposium

People with addictions are seen as having diminished autonomy and contemporary accounts often define their lack of autonomy in reference to an idealized conception of autonomy. In this project, I introduce a new perspective that promotes fullness of autonomy in addicts and provides context for valid instances of diminished autonomy. My argument follows from a perspective developed by Agnieszka Jaworska, in which she highlights how Alzheimer's patients are still capable of having autonomy. I will highlight how focusing on autonomy and addiction provides better insight into autonomy for everyone else rather than centering idealized standards of contemporary accounts of autonomy.

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The Impact Of Power And Need For Closure On Advice Taking And Confidence, Madison Schaefer Apr 2020

The Impact Of Power And Need For Closure On Advice Taking And Confidence, Madison Schaefer

Undergraduate Research and Engagement Symposium

This study explored whether a “power mindset” and Need for Cognitive Closure (NfCC) would influence advice taking. The participant’s level of NfCC was measured prior to the study. After a power mindset manipulation, participants took part in a judgement task and received advice. Their self-confidence and advice taking was measured. It was predicted that possessing a high power mindset would reduce the degree of advice taking. Further, we predicted that higher confidence in one’s judgements would reduce the degree of advice taking. Also, we hypothesized that participants high in NfCC would take advice less than those low in NfCC.

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Executive Control Network Transcranial Alternating Stimulation (Tacs) Modulates Visual Analogical Reasoning, Shana Ward, Sara Temelkova, Emma Sims Apr 2020

Executive Control Network Transcranial Alternating Stimulation (Tacs) Modulates Visual Analogical Reasoning, Shana Ward, Sara Temelkova, Emma Sims

Undergraduate Research and Engagement Symposium

Previous research has linked prefrontal and posterior parietal cortices (key hubs of the Frontoparietal Network; FPN) to analogical reasoning performance. Here we applied transcranial alternating current stimulation (tACS) at theta frequency (6 Hz) to nodes in dorsolateral prefrontal cortex (DLPFC) and posterior parietal cortex (PPC) to investigate the causal role of FPN connectivity in visual and verbal analogical reasoning. 94 participants participated in a between-subjects, double-blind design with three conditions. We found that ‘desynchronized’ stimulation led to enhanced visual analogical reasoning compared to sham and ‘synchronized’ stimulation conditions. These findings support a causal role of the FPN in visual analogical …

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Perceptions Of People Who Misgender Trans Individuals, Lina Flores Wolf Apr 2020

Perceptions Of People Who Misgender Trans Individuals, Lina Flores Wolf

Undergraduate Research and Engagement Symposium

This study explored how people perceive misgendering of transgender people. We looked at participants' perceptions of an interviewer who misgenders an applicant during a job interview, and whether these perceptions vary by personal contact with trans people. We hypothesized that cisgender people who have had contact with a trans person will have less positive impressions of an interviewer who misgenders a trans person. Results show that people who know a trans person will see the interviewer as less warm, and that misgendering is generally perceived as unprofessional, regardless of contact with a trans person.

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Oxygen Limitation Hypothesis, Jillian Schuberth Apr 2020

Oxygen Limitation Hypothesis, Jillian Schuberth

Undergraduate Research and Engagement Symposium

The Oxygen Limitation Hypothesis is a theory that increased oxygen surrounding embryos in development can combat the effects of thermal stress temperatures. When an embryo is subjected to thermal stress temperatures, cranial malformations develop and survival rate goes down. Research has shown that an increased oxygen supply surrounding the embryos during development will combat the effects of thermal stress, in that it will decrease cranial malformations and increase the survival rate.

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Precedence Effects In Binaural Hearing: Do They Exist For Both Time And Level Differences?, Sarah Darnell, Nikita Mahay, Madyson Bondi, Salah Siddiqui Apr 2020

Precedence Effects In Binaural Hearing: Do They Exist For Both Time And Level Differences?, Sarah Darnell, Nikita Mahay, Madyson Bondi, Salah Siddiqui

Undergraduate Research and Engagement Symposium

Up until recently work in the field of binaural hearing has operated under the prevailing belief that interaural time differences (ITDs) and interaural level differences (ILDs) produce similar “precedence effects.” However, recent evidence seems to suggest that precedence effects are much more robust for stimuli carrying an ITD than those carrying an ILD. In order to further explore how the precedence effect varies across binaural cues, we will examine the asymmetries in the processing of ITDs and ILDs as subjects make several left-right judgments based on information carried by an echo pulse in the presence of a binaural cue (ITD …

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Disgust And Vaccine Attitudes, Sophia I. Todorov Apr 2020

Disgust And Vaccine Attitudes, Sophia I. Todorov

Undergraduate Research and Engagement Symposium

Anti-vaccination sentiments have recently increased. Previous research has linked anti-vaccination opinions to fears of contamination. Pro-vaccination messages utilize feelings of fear and disgust. This study aims to determine if there is a link between disgust and strength of persuasive messages. We will conduct an online study through Amazon’s MechanicalTurk. Participants will be shown images that induce disgust or fear and be presented strong or weak arguments. We will measure their vaccine attitudes, private body consciousness, disgust sensitivity, and emotional intelligence. The data will be analyzed using a series of regressions with vaccine attitudes as the outcome variable.

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The Relation Of Authoritative School Climate With Emotion Regulation And Social Competence In High School Adolescents, Grace Ann Fitzgibbons Apr 2020

The Relation Of Authoritative School Climate With Emotion Regulation And Social Competence In High School Adolescents, Grace Ann Fitzgibbons

Undergraduate Research and Engagement Symposium

Over the years, school disciplinary approaches have been largely punitive, with increased suspensions and expulsions for minor disruptive behaviors stemming from a zero-tolerance culture (Smith, 2015). One alternative to this style of discipline, is authoritative school climate. Its emphasis of structure and support has shown positive effects academically and behaviorally, but it is less clear how it affects emotional and interpersonal outcomes for youth (Cornell et al., 2016). The current study expands upon these positive influences of authoritative school climate and how it can ultimately affect emotion regulation and socialization in adolescents. Participants completed questionnaires, such as the Discipline Structure …

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The Effects Of The Interactions Between Microplastic Fibers (Acrylic And Polyester), Microbial Communities, And Triclosan In Freshwater Streams, Masooma Sultan, Astha Chokshi Apr 2020

The Effects Of The Interactions Between Microplastic Fibers (Acrylic And Polyester), Microbial Communities, And Triclosan In Freshwater Streams, Masooma Sultan, Astha Chokshi

Undergraduate Research and Engagement Symposium

The effects of adsorbed POPs and bacterial communities colonizing microplastic surfaces were studied. Triclosan, a common anti-microbial compound which serves as an organic pollutant in the environment was investigated in relation with fibers made in the lab (acrylic and polyester) as a follow-up to a recent experiment done in this lab. This studied the particular interaction between triclosan, the microplastic fibers, and microbial communities to come to a conclusion of what led to a decrease in triclosan. Also including if the adsorption of POPs to microplastic with microbial communities has particular effects that may lead to a decrease in triclosan.

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Changes In Cognitive Control After High-Demand Trials During Continuous Motor Performance: Slower Rts And Increases In Midline Theta, Michael Chammany Apr 2020

Changes In Cognitive Control After High-Demand Trials During Continuous Motor Performance: Slower Rts And Increases In Midline Theta, Michael Chammany

Undergraduate Research and Engagement Symposium

Recent evidence supports competitive queuing models of action sequencing in which early responses in a sequence are more active than later responses. Despite the abundant support for competitive queuing models, evidence explaining the early mechanisms of action planning are poorly understood. Changes in frontal-midline theta-ERS in the EEG appear to be an index of the amount of co-activation of conflict in the environment and may also serve as a measure for buffering processes during the co-activation of multiple responses in an action sequence. Here, we propose to measure EEG activity while participants type 3-letter and 7-letter English words and 3-letter …

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Mechanisms Of Repression Under Stalin, Andrew Fowler Apr 2020

Mechanisms Of Repression Under Stalin, Andrew Fowler

Undergraduate Research and Engagement Symposium

The Great Terror is one of the most significant events concerning the oppression of the Russian people during Stalin’s rule. This project goes beyond the statistics by collecting and analyzing letters written by political prisoners to understand the effects on individuals, families, and society. Drawing on letters from the late 1920s through the end of the Great Terror in 1939, I connect the stories of individuals to broader trends in Stalin’s long-term strategy of political repression.

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Mariposas De Peru, Sydney Nice, Michael Pederson Apr 2020

Mariposas De Peru, Sydney Nice, Michael Pederson

Undergraduate Research and Engagement Symposium

Butterfly and moth (Order Lepidoptera) diversity is used as a bioindicator of ecosystem health. Peru is home to the highest recorded number of butterfly species in the world, currently numbering 3,500 with 7,500 Neotropical species. The high species richness of Lepidoptera in the rainforest surrounding Inkaterra Field Guide Station indicates high biological diversity. Using Inkaterra field guides and iNaturalist, a citizen science tool used to identify fauna and flora, images of butterflies and moths taken in the Amazon region of Madre de Dios, specifically near Inkaterra, were identified and compiled into a list of species.

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Using Human-Mediated Factors To Estimate The Risk Of Red Swamp Crayfish Introduction Across Lentic Waterbodies In Illinois, Eve Hemingway Apr 2020

Using Human-Mediated Factors To Estimate The Risk Of Red Swamp Crayfish Introduction Across Lentic Waterbodies In Illinois, Eve Hemingway

Undergraduate Research and Engagement Symposium

Despite the rising threat of Procambarus clarkii¸ or red swamp crayfish, in freshwater ecosystems, little is known about the factors influencing its introduction into lentic waterbodies. We hypothesize that human-mediated factors of introduction can help estimate where and how P. clarkii move throughout lentic waterbodies in Illinois and Michigan. To test this hypothesis, we created risk assessment models that estimate locations with the highest risk of P. clarkii introduction. In Cook County, Illinois, our model identified 1.4% of all waterbodies as high risk. These results can help concentrate management efforts on waterbodies with the highest risk of P. clarkii …

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Molecular Dynamics Of Naproxen Liquid-Liquid Phase Separation, Lubna Hashim Apr 2020

Molecular Dynamics Of Naproxen Liquid-Liquid Phase Separation, Lubna Hashim

Undergraduate Research and Engagement Symposium

Most new drugs are hydrophobic. This means that they will separate from the water phase just as gasoline would separate from water. In general this means that the drug will aggregate, slowing its absorption by the body. The purpose of out project is to understand the process of liquid-liquid phase separation at an atomic level. Naproxen was chosen as the molecule to study because it has a titratable carboxylic acid group. Thus, in acidic solution, such as in the stomach, it is protonated and uncharged, but in the intestines it would be unprotonated and negatively charged. Thus, our hypothesis is …

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Improving The Security Of Autonomous Vehicles Using Evolutionary Neural Networks, Max Kurinsky, Brook Abegaz Apr 2020

Improving The Security Of Autonomous Vehicles Using Evolutionary Neural Networks, Max Kurinsky, Brook Abegaz

Undergraduate Research and Engagement Symposium

The security of autonomous vehicles refers to the tasks of safeguarding the transportation system from attacks, risks and vulnerabilities. Autonomous vehicles include self-driving vehicles and semi-autonomous vehicles. Although is a very interesting concept, the operation of autonomous vehicles opens doors to various security attacks that require an in-depth research and experimental evaluation.

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Questioning The Mind/Body Dichotomy In Scientific Communication, Masha Bandouil Apr 2020

Questioning The Mind/Body Dichotomy In Scientific Communication, Masha Bandouil

Undergraduate Research and Engagement Symposium

The mind/body dichotomy established in Western society has created a form of knowledge acquisition rooted in the brain. Humans house knowledge physically as well as mentally and by excluding the physical body, an injustice is created towards individuals of different learning styles, education levels, and languages. This research explores the use of movement in communicating scientific knowledge by partnering with The Sarnoff Center of Genetics, in order to create a series of dance films illustrating genetic principles and diseases that disproportionately affect the Jewish community. These films will be posted on the organizations website and will be followed by surveys …

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Assessing The Complexity Of Protein Primary Structures Using Gödel-Type Coding, Ashvi Patel, Daniel J. Graham Apr 2020

Assessing The Complexity Of Protein Primary Structures Using Gödel-Type Coding, Ashvi Patel, Daniel J. Graham

Undergraduate Research and Engagement Symposium

Proteins express multi-faceted complexity through their sizes, functional groups, and biological functions. This research develops an algorithmic coding method to assess primary structure complexity. Primary structures are the sequences of amino acids encoded by the genomes of organisms and viruses. The primary structure of a protein determines all the folding and function properties. The focus here is on the archetypal proteins, myoglobin, and lysozyme. Myoglobin is a well-known oxygen transport protein and lysozyme is a hydrolytic enzyme with antibiotic activity. The methodology is universal and applicable to proteins across species, both on record and yet to be discovered. Why is …

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Robustness Of Cancer Microbiome Studies And Human Steroid Hormones Influence Gut Microbial Community Structure, Sidra Sohail Apr 2020

Robustness Of Cancer Microbiome Studies And Human Steroid Hormones Influence Gut Microbial Community Structure, Sidra Sohail

Undergraduate Research and Engagement Symposium

There is growing evidence suggesting that steroid hormone levels can influence gut microbiota, and potentially vice versa. In this work, we are testing the hypothesis that female steroid hormones, including estrogen and progesterone and their synthetic analogs, may be influencing the structure and function of the human gut microbiome. We have collected gut microbiota from healthy individuals and used an in vitro culture system to expose these communities to varying types and dosages of steroid hormones alongside relevant controls. Timecourse sampling was performed and the results assessed using 16S rRNA gene sequencing of these communities. Using the Dada2 pipeline, Phyloseq, …

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The Influence Of Media Violence Exposure On Explicit And Implicit Emotional Face Processing, Zoa Glab, Laura Stockdale, Sylena Wilson, Marley Hornewer, Sydney Samoska, Joseph Vukov, Rebecca Silton, Robert Morrison Apr 2020

The Influence Of Media Violence Exposure On Explicit And Implicit Emotional Face Processing, Zoa Glab, Laura Stockdale, Sylena Wilson, Marley Hornewer, Sydney Samoska, Joseph Vukov, Rebecca Silton, Robert Morrison

Undergraduate Research and Engagement Symposium

Past studies from our lab have shown that short-term and chronic exposure to media violence can modulate the implicit processing of emotional faces (Stockdale et al., 2015, 2017). However, other research has shown that media violence can increase the speed and accuracy of identifying angry faces when participants are explicitly asked to attend to emotion. To investigate how media violence interacts with attention to emotional stimuli, we asked participants to complete a stop-signal task (SST) with happy and angry face stimuli, while they either categorized the gender (Implicit SST; n = 47) or the facial expression (Explicit SST; n = …

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Annotating The D. Ananassae Genome, Lana Tinawi Apr 2020

Annotating The D. Ananassae Genome, Lana Tinawi

Undergraduate Research and Engagement Symposium

The 4th chromosome in Drosophila species is made of heterochromatin, tightly packed regions that are gene poor. In most genomes, heterochromatic regions are considered transcriptionally-silent; however, this isn’t the case for the 4th chromosome in Drosophila. Many of the genes on the 4th chromosome are required for development and survival; thus, the goal is to identify regulatory regions that allow these genes to be accessible and expressed despite their presence in a heterochromatic environment. Annotating the genomes of Drosophila species and comparing them to the previously annotated genome of D. melanogaster helps us gain a better understanding of these mechanisms.

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Friends, Celeste Martinez Apr 2020

Friends, Celeste Martinez

Undergraduate Research and Engagement Symposium

This presentation was done for my psyc-390 class. I wanted to learn more about personality disorders and the process of diagnosing. I diagnosed all 6 of the characters from Friends. I used the DSM-5 to help me diagnose the characters. For each character I started with a slide with their background information to help get an understanding of the character. Then in the next slide I diagnosed them with a personality disorder and added the diagnostic criteria. I added “yes” if the character met the criteria and added an example.

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Genome Annotation In Drosophila Ananassae, Naisargi Patel Apr 2020

Genome Annotation In Drosophila Ananassae, Naisargi Patel

Undergraduate Research and Engagement Symposium

The Drosophila species’ 4th chromosome has maintained its heterochromatin properties. The goal of the project was to annotate and understand the regulation of the DNA in heterochromatin environment. We annotated contig 52, part of the 4th chromosome of species D. ananassae. The contig 52 contains 3 genes: CG33978 (5 isoforms), CG32006, and bip2-PA. The findings of the bip2 gene annotation showed a disparity between D. ananassae and D. melanogaster species. Although annotating the bip2-PA gene in the genome browser with the evidence provided by Blastx and the gene record finder did not match with what we observed while annotating each …

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Denaturation Of Small Proteins In The Presence Of Sodium Dodecyl Sulfate, Madeline Sheahan Apr 2020

Denaturation Of Small Proteins In The Presence Of Sodium Dodecyl Sulfate, Madeline Sheahan

Undergraduate Research and Engagement Symposium

The purpose of this research is to gain a further understanding of the biochemical mechanisms involved in the denaturation of small proteins using excess concentrations of chemical denaturant sodium dodecyl sulfate (SDS). This work is significant because it allows for the visualization of how SDS interrupts hydrophobic interactions within a protein at the molecular level. The denaturing of proteins render them completely useless and could relieve negative effects from high concentrations of protein in diseases like Alzheimer’s. All of this will be accomplished by utilizing a visual molecular dynamics (VMD) program for simulation. In VMD, four different proteins, each of …

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Synthesis And Application Of Folate-Mediated Photodynamic Therapy Agent Modeled In Zebrafish Embryos, Aishah Kothawala, Allison Monterastelli Apr 2020

Synthesis And Application Of Folate-Mediated Photodynamic Therapy Agent Modeled In Zebrafish Embryos, Aishah Kothawala, Allison Monterastelli

Undergraduate Research and Engagement Symposium

This project investigates use of folate for targeted delivery of photosensitizers to tumors in photodynamic therapy. A photosensitizer, chlorin e6, produces toxic singlet oxygen through excitation by light, causing apoptosis. However, lack of selective targeting remains a challenge in cancer treatments. Folate, an essential vitamin, is used to serve as targeting agent since cancerous cells that are rapidly dividing over-express folate receptors. Folate has been conjugated to Ce6 on a bovine serum albumin carrier and is brought into the cell by endocytosis. The treatment has been applied to zebrafish embryos because the rapidly dividing embryonic cells possess an ortholog to …

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The Role Of Trc In The Development Of Glia In The Nervous System, Nicole Saylor, Andrea Kirincic Apr 2020

The Role Of Trc In The Development Of Glia In The Nervous System, Nicole Saylor, Andrea Kirincic

Undergraduate Research and Engagement Symposium

Glial cells are vital components in the nervous system and are involved in the processes of axon ensheathment, axon targeting, and organ shape. These processes are crucial to a properly functioning nervous system. In previous research, the protein, Raw, was shown to reduce glial proliferation and migration in the developing eye disc of Drosophila. While Raw has been demonstrated to negatively regulate JNK signaling, its mechanism of action remains unclear. Studies in the context of dendrite adhesion and patterning in sensory neurons, have demonstrated that Raw interacts with Tricornered (Trc), an NDR family kinase. Trc is a component of the …

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