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Articles 1771 - 1800 of 12858
Full-Text Articles in Entire DC Network
Questions (And Answers) For Incorporating Nontraditional Grading In Your Statistics Courses, Brenna Curley
Questions (And Answers) For Incorporating Nontraditional Grading In Your Statistics Courses, Brenna Curley
Statistical and Data Sciences: Faculty Publications
Nontraditional grading methods have recently become more common, and as with any large pedagogical shift, there are a number of questions to consider when applying a new grading scheme to a course. This article summarizes four types of nontraditional grading and shares experiences from the authors who have applied them to a variety of courses in statistics. This article is structured as a set of questions and answers, seeking to address many of the concerns and considerations that one may face as they transition a course’s grading structure. Supplementary materials for this article are available online.
Correction: Bayesian Kinetic Modeling For Tracer-Based Metabolomic Data, Xu Zhang, Ya Su, Andrew N. Lane, Arnold Stromberg, Teresa Whei-Mei Fan, Chi Wang
Correction: Bayesian Kinetic Modeling For Tracer-Based Metabolomic Data, Xu Zhang, Ya Su, Andrew N. Lane, Arnold Stromberg, Teresa Whei-Mei Fan, Chi Wang
Statistics Faculty Publications
No abstract provided.
Bayesian Variable Selection With Shrinkage Priors And Generative Adversarial Networks For Fraud Detection, Amina Issoufou Anaroua
Bayesian Variable Selection With Shrinkage Priors And Generative Adversarial Networks For Fraud Detection, Amina Issoufou Anaroua
Graduate Thesis and Dissertation 2023-2024
This research paper focuses on fraud detection in the financial industry using Generative Adversarial Networks (GANs) in conjunction with Uni and Multi Variate Bayesian Model with Shrinkage Priors (BMSP). The problem addressed is the need for accurate and advanced fraud detection techniques due to the increasing sophistication of fraudulent activities. The methodology involves the implementation of GANs and the application of BMSP for variable selection to generate synthetic fraud samples for fraud detection using the augmented dataset. Experimental results demonstrate the effectiveness of the BMSP GAN approach in detecting fraud with improved performance compared to other methods. The conclusions drawn …
Deep Learning One-Class Classification With Support Vector Methods, Hayden D. Hampton
Deep Learning One-Class Classification With Support Vector Methods, Hayden D. Hampton
Graduate Thesis and Dissertation 2023-2024
Through the specialized lens of one-class classification, anomalies–irregular observations that uncharacteristically diverge from normative data patterns–are comprehensively studied. This dissertation focuses on advancing boundary-based methods in one-class classification, a critical approach to anomaly detection. These methodologies delineate optimal decision boundaries, thereby facilitating a distinct separation between normal and anomalous observations. Encompassing traditional approaches such as One-Class Support Vector Machine and Support Vector Data Description, recent adaptations in deep learning offer a rich ground for innovation in anomaly detection. This dissertation proposes three novel deep learning methods for one-class classification, aiming to enhance the efficacy and accuracy of anomaly detection in …
Computation Of Separate Ratio And Regression Estimator Under Neutrosophic Stratified Sampling: An Application To Climate Data, Abhishek Singh, Hemant Kulkarni, Florentin Smarandache, Gajendra K. Vishwakarma
Computation Of Separate Ratio And Regression Estimator Under Neutrosophic Stratified Sampling: An Application To Climate Data, Abhishek Singh, Hemant Kulkarni, Florentin Smarandache, Gajendra K. Vishwakarma
Branch Mathematics and Statistics Faculty and Staff Publications
In this article, we introduce a novel approach by presenting separate ratio and regression estimators in the context of neutrosophic stratified sampling for the very first time, incorporating auxiliary variables. We have conducted a thorough analysis to estimate these newly proposed estimators' bias and mean square error (MSE) up to the first-order approximation. Theoretically using efficiency comparison criteria, our findings demonstrate the superior performance of these estimators compared to traditional unbiased estimators. Also, numerically based on real-life and artificial data, we have shown the supremacy of the neutrosophic stratified sampling over neutrosophic simple random sampling along with the supremacy of …
Numerical Investigation And Statistical Analysis Of The Flow Patterns Behind Square Cylinders Arranged In A Staggered Configuration Utilizing The Lattice Boltzmann Method, M. Abid, N. Yasin, M. Saqlain, S. Ul-Islam, S. Ahmad
Numerical Investigation And Statistical Analysis Of The Flow Patterns Behind Square Cylinders Arranged In A Staggered Configuration Utilizing The Lattice Boltzmann Method, M. Abid, N. Yasin, M. Saqlain, S. Ul-Islam, S. Ahmad
Mathematics & Statistics Faculty Publications
Flow past bluff bodies like square cylinders is important in engineering applications, but flow patterns behind staggered cylinder arrangements remain poorly understood. Existing studies have focused on tandem or side-by-side configurations, while offset orientations have received less attention. The aim of this paper is to numerically investigate flow dynamics and force characteristics behind two offset square cylinders using the single relaxation time lattice Boltzmann method. The effects of changing both the Reynolds number (Re = 1-150) and gap spacing ratio (g* = 0.5-5) between the cylinders are analyzed. Instantaneous vorticity contours, time histories of drag and lift coefficients, power spectra …
Integrating Machine Learning With Cure Models And Associated Inference, Wisdom Aselisewine
Integrating Machine Learning With Cure Models And Associated Inference, Wisdom Aselisewine
Mathematics Dissertations - Archive
Recent advancements in medical treatments have significantly enhanced the rates of recovery for numerous chronic illnesses. This progress has sparked growing interest in developing suitable statistical models capable of handling survival data that includes substantial cure fractions. The mixture cure model finds extensive application in analyzing survival data when there exists a cured subgroup. Standard logistic regression-based approaches for modeling the incidence part of the mixture cure model may suffer from poor predictive accuracy, especially in the presence of high dimensional covariates and/or non-linear covariate effects. To overcome this limitation, we propose the integration of distinct machine learning algorithms with …
The Performance Of Marginal Modeling Methods For Rare Events With Application To Opioid Overdose Mortality And Morbidity, Shawn Nigam
Theses and Dissertations--Epidemiology and Biostatistics
Opioid misuse is a nationwide epidemic, with Kentucky having one of the highest opioid overdose-related fatality rates across all US states. These rates have increased significantly over the past decade, with particularly large increases during the COVID-19 pandemic. This dissertation aims to study the behavior of these increases and the methods for the marginal modeling of count outcomes related to opioid overdose.
Opioid overdose-related fatality rates in Kentucky increased significantly during the COVID-19 pandemic. In this chapter, we characterize the changes in opioid overdose fatality rates in Kentucky and identify associations between potential factors and fatality rates. County-level opioid overdose …
Variable Selection For High-Dimensional Data With Interaction Effects: Methods, Applications, And Inferences, Leiyue Li
Theses and Dissertations--Statistics
For high-dimensional data where the number of variables greatly exceeds the number of observations, selecting important variables while maintaining the required heredity conditions can be challenging. This dissertation is structured into three interconnected parts. In the first part, we propose a variable selection method by implementing a well-known optimization technique, the Genetic Algorithm. An R package was developed to simplify the implementation and usage of the proposed method. We then propose another variable selection method by extending the study from the Genetic Algorithm to a different but related optimization technique, Simulated Annealing. We consider three different hierarchical structures in both …
High-Dimensional Tests And Projection Methods: Subvector Analysis And Matrix Variate Data, Shouryya Mitra
High-Dimensional Tests And Projection Methods: Subvector Analysis And Matrix Variate Data, Shouryya Mitra
Theses and Dissertations--Statistics
In this dissertation, we study projection-based methods to testing problems for high-dimensional data. We also investigate inferential methods for matrix variate data with block compound symmetry (BCS) covariance structure. The research reported in dissertation consists of three projects.
The first project addresses power loss and ill-conditioned error covariance estimates commonly faced by multivariate tests in high-dimensional settings. To overcome these challenges, previous approaches avoided correlations in constructing test statistics, but this required strong assumptions about covariance matrices and dependence structures. More recently, some methods have incorporated correlations by employing random projection into a lower-dimensional space. We develop a unified framework …
Estimation And Testing Of Nonparametric Effects Of Incomplete Multivariate And Repeated Measures Data, Swetalina Maity
Estimation And Testing Of Nonparametric Effects Of Incomplete Multivariate And Repeated Measures Data, Swetalina Maity
Theses and Dissertations--Statistics
In this dissertation, we investigate three distinct but interrelated problems in analyzing repeated measure data with missing values.
The first project is on semiparametric methods for analyzing repeated measures designs with missing values. A closed-form estimator for the parameters and their asymptotic covariance are derived using block partitioning based on the missing data pattern. We also derive the asymptotic distribution of the estimators and construct test statistics to test hypothesis formulated as linear contrasts of the mean vector.
In the second project, we focus on purely nonparametric methods. In this setup, nonparametric treatment effects are defined as functionals of the …
From Non-Parametric Methods To Self-Supervised Learning: Applications In Edge Detection And Image Denoising, Jiacheng Xu
From Non-Parametric Methods To Self-Supervised Learning: Applications In Edge Detection And Image Denoising, Jiacheng Xu
Theses and Dissertations--Statistics
This dissertation explores advanced methodologies for edge detection and image denoising through the application of both traditional non-parametric methods and modern self-supervised deep learning techniques. Beginning with non-parametric approaches, we refine surface fitting and jump detection criteria to enhance the detection of discontinuous regression surfaces in grayscale images. These foundational techniques are extended to color images, with analyses across RGB and CIELAB color spaces to improve edge detection accuracy. We then introduce a self-supervised neural network model that integrates Masked Modeling into the Bi-Directional Cascade Network (BDCN) framework. This approach shows the potential of reducing the dependency on annotated data …
Patterns Into Pathways For Improving Safety Culture: Refined Latent Class Analysis Informs Tailored Decision Support For South Carolina Dss Safety Culture Improvements, Michaela Voit
Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)
The rising prevalence of exposures to adverse childhood experiences (ACEs) demands a coordinated public health response, as a significant body of research details the cumulative impact of ACEs on chronic morbidities contributing to reduced life expectancy. Child welfare workers (CWW) are embedded in this public health effort, tasked with preventing and mitigating the impacts of ACEs through family and prevention services. The National Partnership for Child Safety (NPCS) may improve the wellbeing of CWWs and the effectiveness of Child Welfare (CW) services by improving the quality of safety culture within CW organizations. To inform NPCS quality improvement efforts, our project …
Imputation Strategies For Different Categories Of Missing Data, Karthik Chalumuri
Imputation Strategies For Different Categories Of Missing Data, Karthik Chalumuri
Honors Theses and Capstones
Addressing missing data in research is crucial for ensuring the reliability and validity of study findings, yet it remains a significant challenge. This study investigates the impact of missing data on research outcomes and explores the underutilization of existing tools for managing missingness, potentially leading to gaps in critical information with tangible implications for decision-making processes (Dziura et al.).
Focusing on the different categories of missing data—Missing Completely At Random (MCAR), Missing At Random (MAR), and Missing Not At Random (MNAR)—this research examines various imputation strategies tailored to each category. Specifically, we compare the efficacy of several model-based imputation methods, …
Applications Of Independent And Identically Distributed (Iid) Random Processes In Polarimetry And Climatology, Dan Kestner
Applications Of Independent And Identically Distributed (Iid) Random Processes In Polarimetry And Climatology, Dan Kestner
Dissertations, Master's Theses and Master's Reports
The unifying theme of this thesis is the characterization of “perfect randomness,” i.e., independent and identically distributed (IID) stochastic processes as these are applied in physical science. Two specific and mathematically distinct applications are chosen: (i) Radar and optical polarimetry; (ii) Analysis of time series in meteorology. In (i), IID process of a special kind, namely, with a distribution defined by symmetry, is used to link its multivariate Gaussian density to uniformity on the Poincaré sphere. This “statistical ellipsometry” approach is then used to relate polarimetric mismatches or imbalances to ellipsometric variables and suitably chosen cross-correlation measures. In (ii), recently …
Stigma And Efficacy Beliefs Regarding Opioid Use Disorder Treatment And Naloxone In Communities Participating In The Healing Communities Study Intervention, Nicky Lewis, Barry Eggleston, Redonna K. Chandler, Dawn Goddard-Eckrich, Jamie E. Luster, Dacia Beard, Emma Rodgers, Rouba A. Chahine, Philip M. Westgate, Shoshana N. Benjamin, Janae Holloway, Thomas Clarke, R. Craig Lefebvre, Michael D. Stein, Donald W. Helme, Jennifer Reynolds, Sharon L. Walsh, Darcy Freedman, Nabila El-Bassel, Kara Stephens, Anita Silwal, Michelle R. Lofwall, Janet E. Childerhose, Hilary L. Surratt, Brooke N. Crockett, Amy L. Farmer, James L. David, Laura Fanucchi, Judy Harness, Ben Wilburn, Kelli Bursey, Kristin Mattson, Sarah Mann, Rebecca D. Jackson, Aimee Shadwick, Katherine Calver, Deborah Chassler, Jennifer Kimball, Nancy Regan, Jeffrey H. Samet, Rachel Sword-Cruz, Michael D. Slater
Stigma And Efficacy Beliefs Regarding Opioid Use Disorder Treatment And Naloxone In Communities Participating In The Healing Communities Study Intervention, Nicky Lewis, Barry Eggleston, Redonna K. Chandler, Dawn Goddard-Eckrich, Jamie E. Luster, Dacia Beard, Emma Rodgers, Rouba A. Chahine, Philip M. Westgate, Shoshana N. Benjamin, Janae Holloway, Thomas Clarke, R. Craig Lefebvre, Michael D. Stein, Donald W. Helme, Jennifer Reynolds, Sharon L. Walsh, Darcy Freedman, Nabila El-Bassel, Kara Stephens, Anita Silwal, Michelle R. Lofwall, Janet E. Childerhose, Hilary L. Surratt, Brooke N. Crockett, Amy L. Farmer, James L. David, Laura Fanucchi, Judy Harness, Ben Wilburn, Kelli Bursey, Kristin Mattson, Sarah Mann, Rebecca D. Jackson, Aimee Shadwick, Katherine Calver, Deborah Chassler, Jennifer Kimball, Nancy Regan, Jeffrey H. Samet, Rachel Sword-Cruz, Michael D. Slater
Biostatistics Faculty Publications
Background The HEALing Communities Study (HCS) included health campaigns as part of a community-engaged intervention to reduce opioid-related overdose deaths in 67 highly impacted communities across Kentucky, Massachusetts, New York, and Ohio. Five campaigns were developed with community input to provide information on opioid use disorder (OUD) and overdose prevention, reduce stigma, and build demand for evidence-based practices (EBPs). An evaluation examined the recognition of campaign messages about naloxone and whether stigma and efficacy beliefs regarding OUD treatment and naloxone changed in HCS intervention communities.
Methods Data were collected through surveys offered on Facebook/Instagram to members of communities participating in …
Pitching The Use Of Squared And Interaction Terms In Regression Via Baseball Heat Maps, Lucas Chepelsky
Pitching The Use Of Squared And Interaction Terms In Regression Via Baseball Heat Maps, Lucas Chepelsky
Williams Honors College, Honors Research Projects
This project will examine the impact of using second-order terms in regression. For illustration, we use an example of regression where a baseball player's three by three heat map, including the height and distance from inside to outside of the pitch, are variables used to predict batting average. We find that second-order terms are crucial in discovering nonlinear relationships and interaction effects in regression models, and maintain that the common practice of using first-order additive models is insufficient.
To Mean Or Not To Mean: An Investigation Of Regression To The Mean, Hunter Ellis
To Mean Or Not To Mean: An Investigation Of Regression To The Mean, Hunter Ellis
Williams Honors College, Honors Research Projects
Regression to the mean is a statistical phenomenon that can hide important characteristics of what is truly happening in a research study. Caused by statistical randomness, regression to the mean occurs when extreme values, high or low, are followed by less extreme values. To correctly deal with it, one must understand what it is and how to distinguish its effect on conclusions made from the data. This paper provides examples of regression to the mean in both a medical and academic performance study and explains simple identifiers one can observe. Those are then followed up by the introduction of the …
Ensemble Classification: An Analysis Of The Random Forest Model, Jarod Korn
Ensemble Classification: An Analysis Of The Random Forest Model, Jarod Korn
Williams Honors College, Honors Research Projects
The random forest model proposed by Dr. Leo Breiman in 2001 is an ensemble machine learning method for classification prediction and regression. In the following paper, we will conduct an analysis on the random forest model with a focus on how the model works, how it is applied in software, and how it performs on a set of data. To fully understand the model, we will introduce the concept of decision trees, give a summary of the CART model, explain in detail how the random forest model operates, discuss how the model is implemented in software, demonstrate the model by …
Climate Change's Effect On Flow Regime, Alexander Ialenti
Climate Change's Effect On Flow Regime, Alexander Ialenti
Williams Honors College, Honors Research Projects
This project will test to see if there is a percent increase in non-perennial streams sampled from 2003-2021. Using data provided by The Cleveland Metroparks, sampling events will be separated by date, flow regime classification, and rain data. Current literature supports the claim that many perennial streams, streams that flow year-round, will become non-perennial streams over time. This shift is predicted to be caused by a change in rain patterns. Both the interval between rain events and the intensity of rainfall per event are predicted to increase. My hypothesis is that there will be an increase in the percentage of …
Multiple Imputation For Robust Cluster Analysis To Address Missingness In Medical Data, Arnold Harder, Gayla R. Olbricht, Godwin Ekuma, Daniel B. Hier, Tayo Obafemi-Ajayi
Multiple Imputation For Robust Cluster Analysis To Address Missingness In Medical Data, Arnold Harder, Gayla R. Olbricht, Godwin Ekuma, Daniel B. Hier, Tayo Obafemi-Ajayi
Mathematics and Statistics Faculty Research & Creative Works
Cluster Analysis Has Been Applied To A Wide Range Of Problems As An Exploratory Tool To Enhance Knowledge Discovery. Clustering Aids Disease Subtyping, I.e. Identifying Homogeneous Patient Subgroups, In Medical Data. Missing Data Is A Common Problem In Medical Research And Could Bias Clustering Results If Not Properly Handled. Yet, Multiple Imputation Has Been Under-Utilized To Address Missingness, When Clustering Medical Data. Its Limited Integration In Clustering Of Medical Data, Despite The Known Advantages And Benefits Of Multiple Imputation, Could Be Attributed To Many Factors. This Includes Methodological Complexity, Difficulties In Pooling Results To Obtain A Consensus Clustering, Uncertainty Regarding …
A Case Study On Variations In Network Structure And Cross- Sector Alignment In Two Local Systems Serving Pregnant And Parenting Women In Recovery, Liza M. Creel, Yana Feygin, Madeline Shipley, Deborah Winders Davis, Tiffany Cole Hall, Chaly Downs, Stephanie Hoskins, Natalie Pasquenza, Scott D. Duncan
A Case Study On Variations In Network Structure And Cross- Sector Alignment In Two Local Systems Serving Pregnant And Parenting Women In Recovery, Liza M. Creel, Yana Feygin, Madeline Shipley, Deborah Winders Davis, Tiffany Cole Hall, Chaly Downs, Stephanie Hoskins, Natalie Pasquenza, Scott D. Duncan
Biostatistics Faculty Publications
Objective: To describe network structure and alignment across organizations in healthcare, public health, and social services sectors that serve pregnant and parenting women with substance use disorder (SUD) in an urban and a rural community.
Data Sources and Study Settings: Two community networks, one urban and one rural with each including a residential substance use treatment program, in Kentucky during 2021.
Study Design: Social network analysis measured system collaboration and cross-sector alignment between healthcare, public health, and social services organizations, applying the Framework for Aligning Sectors. To understand the alignment and structure of each network, we measured network density overall …
Higher First 30-Day Dose Of Buprenorphine For Opioid Use Disorder Treatment Is Associated With Decreased Mortality, Feitong Lei, Michelle R. Lofwall, Jana Mcanich, Reuben Adatorwovor, Emily Slade, Patricia R. Freeman, Daniela Moga, Nabarun Dasgupta, Sharon L. Walsh, Rachel Vickers-Smith, Svetla Slavova
Higher First 30-Day Dose Of Buprenorphine For Opioid Use Disorder Treatment Is Associated With Decreased Mortality, Feitong Lei, Michelle R. Lofwall, Jana Mcanich, Reuben Adatorwovor, Emily Slade, Patricia R. Freeman, Daniela Moga, Nabarun Dasgupta, Sharon L. Walsh, Rachel Vickers-Smith, Svetla Slavova
Biostatistics Faculty Publications
Objective: Buprenorphine is a medication for opioid use disorder that reduces mortality. This study aims to investigate the less well-understood relationship between the dose in the early stages of treatment and the subsequent risk of death.
Methods: We used Kentucky prescription monitoring data to identify adult Kentucky residents initiating transmucosal buprenorphine medication for opioid use disorder (January 2017 to November 2019). Average daily buprenorphine dose for days covered in the first 30 days of treatment was categorized as ≤8 mg, >8 to ≤16 mg, and >16 mg. Patients were followed for 365 days after the first 30 days of buprenorphine …
Synergetic Effects Of Democracy And Economic Development On Income Inequality And The Role Of Relative Political Capacity, Nazif Sali
CGU Theses & Dissertations
Diving into the complex dynamics of income inequality, this dissertation studies the multifaceted relationships between democracy, economic development, and inequality, placing a spotlight on the mediating influence of Relative Political Capacity (RPC). Uncovering the pivotal role of RPC as democracies advance and economies progress, this research navigates the contours of income inequality. By dissecting distinct sub-samples of OECD and non-OECD countries, nuanced insights surface. Employing robust methodologies such as ordinary least squares regressions and fixed effects analysis, I argue that targeted policies addressing inequality can not only foster inclusive economic growth but also fortify the foundations of democratic institutions. As …
Intelligent Capabilities Of Traditional Knowledge Organization Methods, Xinning Su
Intelligent Capabilities Of Traditional Knowledge Organization Methods, Xinning Su
Journal of Scientific Information Research
[Purpose/significance]By analyzing the system and rules of traditional knowledge organization methods, the intelligent capabilities of traditional knowledge organization methods are refined and integrated into artificial intelligence(AI) technology, to enhance the precision and efficiency of AI in information processing. [Method/process]This paper reviews the development of knowledge organization and analyses the inherit structure and mechanisms of traditional knowledge organization methods. [Result/conclusion]Research suggests that over centuries of development and evolution, knowledge organization has gained the ability to reflect knowledge systems and disciplinary systems across different disciplines from diverse perspectives, establish semantic relations from diverse knowledge associations, and associate and integrate knowledge of different …
A Quantitative Analysis Of Seaplane Accidents From 1982-2021, David C. Ison
A Quantitative Analysis Of Seaplane Accidents From 1982-2021, David C. Ison
International Journal of Aviation, Aeronautics, and Aerospace
This study aimed to assess and analyze all historical National Transportation Safety Board accident reports since 1982. For analysis, reports were bisected into seaplane (float, amphibian, and hull) and non-seaplane groups. Findings showed that there is a deficiency in the level of available detail on the seaplane fleet and cadre of seaplane pilots in the U.S. During the most recent ten years of complete data (2012-2021) showed a negative trend in all accidents and fatal accidents, although only the latter being statistically convincing. During this timeframe, seaplane accident pilots had significantly higher total time and age than other groups (non-seaplane …
Investigation Of The Effect Of Preparation Parameters On The Structural And Mechanical Properties Of Gelatin/Elastin/Sodium Hyaluronate Scaffolds Fabricated By The Combined Foaming And Freeze-Drying Techniques, Mansour Qamash, S. Misagh Imani, Meisam Omidi, Ciara Glancy, Lobat Tayebi
Investigation Of The Effect Of Preparation Parameters On The Structural And Mechanical Properties Of Gelatin/Elastin/Sodium Hyaluronate Scaffolds Fabricated By The Combined Foaming And Freeze-Drying Techniques, Mansour Qamash, S. Misagh Imani, Meisam Omidi, Ciara Glancy, Lobat Tayebi
Electrical & Computer Engineering Faculty Publications
This paper aimed to evaluate the effects of different preparation parameters, including agitation speed, agitation time, and chilling temperature, on the structural and mechanical properties of a novel gelatin/elastin/sodium hyaluronate tissue engineering scaffold, recently developed by our research group. Fabricated using a combination of foaming and freeze-drying techniques, the scaffolds were assessed to understand how these parameters influence their morphology, internal microstructure, porosity, mechanical properties, and degradation behavior. The fabrication process used in this study involved preparing a homogeneous aqueous solution containing 8% gelatin, 2% elastin, and 0.5% sodium hyaluronate (w/v), which was then subjected to mechanical agitation at speeds …
Bar-Code Variable: A Novel Approach To Efficiently Find Interaction Effects, Lee Sak Park
Bar-Code Variable: A Novel Approach To Efficiently Find Interaction Effects, Lee Sak Park
Theses and Dissertations--Statistics
This paper introduces the bar-code variable, a novel method for processing a sequence of binary explanatory variables efficiently in the linear regression modeling framework. Represented as an integer or a sequence of bits, the bar-code variable captures infor- mation on original binary variables and their potential interaction effects. Utilizing the bar-code variable, the study explores streamlined feature selection in linear re- gression modeling with binary explanatory variables. The paper demonstrates how the bar-code variable, through re-parameterization, facilitates the transition from cell means estimates, µ̂, in the cell-means ANOVA model to coefficient estimates, β̂, in the linear regression model, and vice …
On Generative Models And Joint Architectures For Document-Level Relation Extraction, Aviv Brokman
On Generative Models And Joint Architectures For Document-Level Relation Extraction, Aviv Brokman
Theses and Dissertations--Statistics
Biomedical text is being generated at a high rate in scientific literature publications and electronic health records. Within these documents lies a wealth of potentially useful information in biomedicine. Relation extraction (RE), the process of automating the identification of structured relationships between entities within text, represents a highly sought-after goal in biomedical informatics, offering the potential to unlock deeper insights and connections from this vast corpus of data. In this dissertation, we tackle this problem with a variety of approaches.
We review the recent history of the field of document-level RE. Several themes emerge. First, graph neural networks dominate the …
Difs And Bayescluster: Novel Methods For Single_Cell Rna Sequencing Analysis, Kun Liu
Difs And Bayescluster: Novel Methods For Single_Cell Rna Sequencing Analysis, Kun Liu
Theses and Dissertations--Statistics
Single-cell RNA sequencing (scRNA-seq) has transformed our understanding of cellular heterogeneity and gene expression dynamics. Despite its potential, the inherent noise and sparsity of scRNA-seq data pose significant challenges in clustering cells into biologically meaningful groups. This dissertation addresses these challenges through two novel methodologies aimed at enhancing the accuracy and robustness of scRNA-seq data analysis.
First, we introduce the Differential Feature Selection (DIFS) framework, designed to improve the identification of differential features in scRNA-seq data. DIFS employs a two-stage marker identification process. In the first stage, a modified Dip Test is used to filter and identify genes with significant …