Digital Commons Network^™

Investigating Virus Clearance Via Ph Inactivation During Biomanufacturing, Wenbo Xu

Biomedical Engineering Undergraduate Honors Theses

In the processing of biopharmaceuticals, viral clearance and viral safety are important for the development of monoclonal antibodies. Murine xenotropic leukemia virus (XMuLV) is one of the retroviruses, recommended by Food and Drug Administration (FDA) as a model virus for viral clearance via inactivation from therapeutics derived from Chinese hamster ovary cells (CHO). A robust and effective method was investigated to clear or inactivate endogenous viruses by low pH inactivation. The effects of different conductivity and inactivated time on XMuLV clearance was determined. Acetate buffer was prepared with different conductivity, and 2% XMuLV was spiked into acetate buffer. XMuLV virus …

The Effects Of Eicosapentaenoic Acid (Epa) And Docosahexaenoic Acid (Dha) On Brown Adipogenesis In Stem Cell Culture, Darynne Dahlem

Animal Science Undergraduate Honors Theses

Polyunsaturated fatty acids (PUFAs), especially eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), are major maternal dietary supplements due to their positive benefits on neurological tissue growth during the first 12 weeks of gestation. Previous studies show that EPA and DHA inhibit muscle formation but promote adipogenesis. However, no research has addressed the question whether high intake of EPA and DHA affects brown fat development during gestation. The objective of this study was to measure the effect of EPA and DHA supplement on brown adipogenesis and potential pathways related to mitochondrial biosynthesis using fibroblasts as in vitro model. Using Oil-Red-O staining …

Queer Survivors Of Intimate Partner Violence : Developing Queer Theory And Practice For Responsive Service Provision, Autumn M. Bermea

Theses, Dissertations and Culminating Projects

Queer individuals (e.g., non-heterosexual and/or non-cisgender) are at a heightened vulnerability to experience intimate partner violence (IPV) than heterosexual and/or cisgender individuals. However, there are few inclusive IPV services available specifically for queer individuals. This may be due to a lack of training or the presence homo/bi/transphobia. This dissertation fills this gap by connecting theory, practice, and research. It proposes a strain of queer theory that is applicable to interpreting IPV through the recognition of heteronormative social structures and heterogeneity of the queer community. Through collaboration with queer/queer friendly IPV service providers, theory was applied to develop empirically-based recommendations for …

A Post-Intentional Phenomenological Exploration Of A Sense Of Safety In Three-Generation Low-Income Families, Kaitlin Brigid Mulcahy

Theses, Dissertations and Culminating Projects

Despite a wide body of literature that suggests safety as critical to human development and individual well-being (Ainsworth, Blehar, Waters, & Wall, 1978; Bowlby, 1969; Fosha, Siegel & Solomon, 2009; Marvin, Cooper, Hoffman & Powell, 2002; Porges, 2011; Tronick, 2007), a comprehensive review of the literature found a paucity of research that addresses the phenomenon of a sense of safety within family units. This study sought to fill this gap through an entirely strengths-based design that made use of post-intentional phenomenological methods and arts-based analysis. The research question that guided this study was: How is the phenomenon of a sense …

The Role Of Women In Terrorism, Zeynep Bayar

Dissertations, Theses, and Capstone Projects

The main purpose of this paper is to understand what motivate women to join terrorist groups and why these organizations prefer to work with female terrorists. Although each woman has different reasons to involve in terrorist groups, this research demonstrates 'religious, political and personal' reasons as the major motivating factors. This study also focuses on the question of why women are the targets of terror recruiters. In order to answer these, the research analysis examines 'psychological, gender, and media' factors as major recruitment reasons of terrorist organizations. This study also analyzes the similarities and differences between female terrorists' profiles of …

Navigating Colorism And Racial Identity In Dominican Women, Christine Hernandez

Dissertations, Theses, and Capstone Projects

Colorism has been perpetuated in Dominican culture across generations. That along with a colonial mentality has shaped the racial identity and ideologies of their people. I explore what historical and societal factors play into identity in Dominican women. Additionally, I delve into the history of blackness on the island of Hispañola and how it has led to the perpetuation of colorism. I show how this perpetuation influences the racial self-identity of Dominican women through different forms of media and culture.

Italian/Americans And The American Racial System: Contadini To Settler Colonists?, Stephen J. Cerulli

Dissertations, Theses, and Capstone Projects

This thesis explores the relationship between ethnicity and race, “whiteness,” in the American racial system through the lens of Italian/Americans. Firstly, it overviews the current scholarship on Italian/Americans and whiteness. Secondly, it analyzes methodologies that are useful for understanding race in an American context. Thirdly, it presents a case study on the Columbus symbol and the battle over identity that arose out of, and continues over, this symbol. Finally, this thesis provides suggestions using the case study and methodologies to open up new ways of understanding Italian/Americans and the American racial system.

Caring Choices? Supporting And Dreaming With Students In New York City’S Stratifying High School Admissions System, Megan R. Moskop

Dissertations, Theses, and Capstone Projects

In New York City, all eighth graders attending public school must apply for high school. They have 400 schools from which to choose, and they must create a ranked list of twelve choices. They are then matched to one school. The results of this process play a large role in creating one of the most segregated and unequal school systems in the country. In “Caring choices? Supporting and dreaming with students in New York City’s stratifying high school admissions system,” I share an autoethnographic account that spans ten years of work as an activist educator striving both to support students …

Adults Formerly In Foster Care Narrate Schooling Experiences, Danielle Walker

Dissertations, Theses, and Capstone Projects

Roughly 400,000 children are in foster care in the United States (Lash, 2017, p. 5). These youth are less likely to graduate high school than their non-foster peers (Barnow et al., 2015). While several barriers contribute to the poor educational outcomes for children in foster care, research has noted that the label “foster child” is associated with negative connotations and differential teacher treatment (Altshuler, 2003; Finkelstein, Wamsley, & Miranda, 2002). In spite of such observations, little research has emphasized the perspectives of those in foster care. To fill this gap, this qualitative study posed the following question: How do adults …

Virtually Healthy: Using Virtual Ethnography To Survey Healthcare Seeking Practices Of Transgender Individuals Online, Rogelio Arenas

UNLV Theses, Dissertations, Professional Papers, and Capstones

The use of digital spaces becomes more prevalent as technologies improve and more individuals become connected online. For many, the virtual world may become the primary means by which they engage socially and commercially with larger society. For individuals who identify as transgender or gender nonconforming, the virtual world serves as an environment where the fluidity of identity construction, the security of anonymity, and the physical separation provided by using a digital medium allows for the creation of a secure space for social engagements that may otherwise be discriminatory or infeasible in physical interactions. The stigma, discrimination, and prejudice experienced …

Risky Business: A Comparative Analysis Of Risk Instruments Of Sports Security Arenas, Antonia Peterson

Honors Theses

Risk assessments in the sports security domain are generally accepted as objective reports with a small margin of subjective information included. The researcher interviewed 10 risk professionals in the sports security industry to evaluate and compare the handling of objective information such as statistical data and historical reports to expert judgment. Interviews were examined using a grounded theory methodology with the Atlas T.I. software program to create overarching themes and a theory of the roles of objective and subjective information within security discourse. Findings pointed to a heavy reliance on expert opinion in comparison to data reports. A moderate amount …

Attitudes Of Men And Women Toward Sexual Assault: The Role Of Stigma, Self-Stigma, And Gender Roles, Annie Hendricks

Honors Theses

Sexual assault is an issue pervaded with stigmas, whether imposed on a person from a social source or from oneself. Stigmas have shown to be harmful to a survivor’s recovery from trauma (Deitz, Williams, Rife, & Cantrell, 2015) and may influence whether or not a survivor of sexual assault reports an incident of sexual assault (Spencer, Mallory, Toews, Stith, & Wood, 2017). One factor that contributes to internalizing a stigma to form a self-stigma is the anticipated reaction a survivor faces when he or she discloses an incident of sexual abuse (Murray, Crowe, & Overstreet, 2018). To determine how gender …

Motivations In Volunteer Tourism: The Mini-Mission Concept, Lindsey Hargrave

Honors Theses

In our increasingly globalized world, people have more access to each other than ever before. With the plight of those in faraway places more visible now, people have demonstrated a desire to help. In the last twenty years, the industry known as volunteer tourism has grown exponentially. From its roots as an eco-friendly alternative, this industry has evolved into a multibillion-dollar global phenomenon. As volunteer tourism evolved, many different subsets of this concept emerged. One of which includes the idea of a mini-mission. The mini-mission is traditionally a short, volunteer tourism trip, however, it also includes some religious aspects. Academics …

Is It Too Late For The Federal Government To Reverse Course On How We Legally Recognize Gender?, Stephanie Poget

Honors Theses

This paper focuses on the definitions and interpretations that govern the protections of transgender American citizens as defined by the Civil Rights Act as well as how the Trump Administration’s agenda might impact the transgender community. Included in this paper is a study of historical events and case law that illustrate the protections heterosexual American citizens have compared to that of transgender Americans.

Something’S In The Water: A Look At How Creativity And Innovation Can Prevent Future Water Crises, Tristan Holiday-Nowden

Creativity and Change Leadership Graduate Student Master's Projects

The purpose of this project is to raise awareness and create a level of consciousness about water, unlike anything we have seen in the past. This project presents a synthesis of current writings and ideologies from the fields of Environmental Science and Water Research. As well as think pieces and informative news articles from various publications.

To illustrate the damaging effects of water contamination, water pollution, and water scarcity; Flint, Michigan will serve as a case study. After diagnosing and defining the problem using the Creative Problem Solving (CPS) framework. This project will explore the challenge and look at the …

Losing Louisiana: Race, Techno-Science, And The Disappearing Geographies Of The Lower Mississippi River Delta, Monica Patrice Barra

Dissertations, Theses, and Capstone Projects

Based on eighteen months of ethnographic and historical research in southeast coastal Louisiana (USA), this dissertation explores the racial histories, engineering and scientific practices, and geophysical processes that have shaped land loss and coastal restoration in the lower Mississippi River Delta. Rather than treating land loss simply as a natural process or matter of environmental restoration, this ethnography examines its cultural, material, and political dimensions, especially for communities of color that have already experienced long histories of loss — of property, livelihood, and political rights. A focus on the geophysical transformations of the river - dictating land growth, sinking, and …

Sweeping Exposures: Lead Poisonings And Black Working Poor Populations In The United States, Shirley Reid

Dissertations, Theses, and Capstone Projects

The focus of my thesis is to explore some of the realities that the impoverished urban black poor populations face in America today. The goal of my thesis is to illustrate how poverty is reproduced within impoverished neighborhoods through the idea and mechanism of lead exposure, by recognizing how specific exposure to the element lead and its by-products is both a symbol and a material cause of black urban poor illness and disability. There is no mistake that people living in the U.S. are aware of the social injustices against black populations in the form of racial injustice. However, …

Resisting Industrial Food Systems On The Web: How Non-Profit Organizations Use Digital Technology For Sustainability Education, Aleksandr Segal

Dissertations, Theses, and Capstone Projects

This thesis examines the link between how community-based organizations use digital tools with the fundamentally resistance-based philosophy that these organizations have at the core of their mission. It aims to uncover how non-profit organizations (NPOs) that work in community development through food and agriculture use digital tools, and how their digital communication strategies relate to issues of resistance to neoliberalism and industrialization in the food and agriculture sectors.

Using a foundation of existing literature on food and agriculture, climate change and waste management, critical theory, and technology in pedagogy, this thesis will contextualize how non-profits resist neoliberal regimes of de-traditionalization …

Cultural Heritage Preservation In The Context Of Climate Change Adaptation Or Relocation: Barbuda As A Case Study, Martha B. Lerski

Dissertations, Theses, and Capstone Projects

This case study introduces an arts camp methodology of engaging communities in identifying their key cultural heritage features, thus serving as a meta study. It presents original research based on field studies on the climate-vulnerable Caribbean island of Barbuda during 2017 and 2018. Its Valued Cultural Elements survey, enabling precise identification of key tangible and intangible art forms and biocultural practices, may serve as a basis for further studies. Such approaches may facilitate future research or planning as climate-vulnerable communities harness Local or Indigenous Knowledge for purposes of biocultural heritage preservation, or towards adaptation or relocation. I report on findings …

Queerness, Witchcraft, And Embodied Presence: Aesthetic Knowings Of What A Body Can Do, Megan Bigelow

Dissertations, Theses, and Capstone Projects

Taking as a point of entry the critique of representation and affirming the limitations of the cuts that language makes, this capstone project explores the imbrications and assemblages between Foucault’s concept of subjugated knowledges, witchcraft and other body-based ways of knowing and being, and the consciousness of non-human forms such as plants and through the framework of non-representational theory, process philosophies, aesthetics, queerness, and the concept of difference itself.

Since such theories themselves are living, breathing entities, this capstone project explores the ideological split that has occurred between sacred and secular beliefs, moving through different figures such as nuns and …

Social Networks And Science Identity: Does Peer Commitment Matter?, Grace Maridyth Kelly

Department of Sociology: Dissertations, Theses, and Student Research

White men continue to be overrepresented in STEM fields compared to women and minorities, despite several decades of scholarly interest the disparity. Studies have shown that early adolescence is when children begin to lose interest in science. It is also in this period, that children start to develop ideas and stereotypes about who should be a scientist. It is essential that youth are able to see themselves as science kinds of people. Students who have strong science identities have been shown to perform better in science classes, retain interest in science and continue on to STEM careers. During adolescence, peer …

Drinking Behaviors, Relationships And Recovery: A Relational Sociological Examination Of Addiction, Maia C. Behrendt

Department of Sociology: Dissertations, Theses, and Student Research

Examination of addiction from the theoretical framework of relational sociology contributes to growing efforts to understand and develop addiction recovery programs that focus on the restoration of important social relationships and ties. Aims of the study include understanding how alcohol addiction has been addressed in earlier sociological studies and to provide evidence for how relational sociology may be utilized to better understand and explain how alcoholics and Alcoholics Anonymous operate within Bateson’s Theory of Alcoholism and Addiction. Through a qualitative study and analysis of 20 in-depth audio recorded interviews with individuals in either active recovery or active drinking, this study …

Becoming A Master Manager: An Analysis Of Snap Recipient Stories Of Navigating Government Assistance, Kallie Gay

Electronic Theses and Dissertations

This study examines experiences of utilizing government assistance in the United States. It focuses on the ways in which persons participating in the Supplemental Nutrition Assistance Program (SNAP) communicatively managed their lives in relation to their role in the program. Specifically, the research reveals that SNAP recipients are master managers. After synthesizing the pre-existing body of research concerning social assistance in the U.S. and its effects on those who utilize it, the author argues that sharing the stories of marginalized groups can serve to reduce stigma surrounding government assistance participation. Employing a Feminist Standpoint Theory sensibility to elicit such stories, …

Factors Contributing To Low Adequate Prenatal Care Rates In Orange County, Florida, Lauren Daniel

Electronic Theses and Dissertations

In 2017, only 56% of births in Orange County, Florida, received adequate prenatal care - care that has been shown to prevent maternal and infant death. The Florida Department of Health uses the Kotelchuck Index to determine care adequacy. This index rates care adequacy based on when the mother first receives care, and how many recommended appointments she attends. Prenatal care is rated "inadequate" if it starts after the fourth month of pregnancy, and/or if less than half of the recommended appointments are attended. Receiving earlier and consistent prenatal care has been shown to be an effective way to improve …

Trans Stories, Trans Voices: How The Internet Empowers Transgender Creators To Have Agency In Trans Fiction, Pepper J. Heifner

Undergraduate Honors Theses

Although many advocates believe that the increased representation of transgender people in mainstream fiction will lead to more understanding for the transgender community, many transgender scholars (Page, Richards) are critical of representation that is created without any involvement of actual transgender people. Some fear that the more radical perspectives of trans lives are being erased and replaced with a homogenous idea of the kinds of trans people who are “acceptable” (cárdenas). To avoid this homogeneity, it is important to allow for a multiplicity of trans perspectives and empower transgender people to have agency over their own narratives.

The goal of …

Silver-Based Microbial Check Valve For Spacecraft Potable Water Systems, Rogelio E. Garcia

Chemical Engineering Undergraduate Honors Theses

As human space exploration increases, the development of a more efficient potable water treatment system suited for spacecraft becomes crucial. This Waste-management Education Research Consortium (WERC) challenge was designed to explore the viability of microbial control through the utilization of silver ions as a biocide for possible integration into the Tranquility Node 3 water purification system aboard the International Space Station (ISS). Current systems using iodine risk causing hyperthyroidism from overexposure; however, silver can be safely ingested without this side effect. After researching silver delivery methods including electrochemical ion production, controlled release, or a combination of the two, our team …

The Effects Of A Literacy-Based Mentoring Program On Empowering Preadolescent Girls In Their Development Of Confidence, Self-Concept, And Leadership Skillset, Sophia Vincent

Curriculum and Instruction Undergraduate Honors Theses

This study focuses on empowering preadolescent girls to develop confidence and move from a fixed to growth mindset, take responsibility for their actions, turn failures into learning opportunities, and cultivate a love for self. GIRLS: Leaders on the Rise is a literacy-based mentoring program for preadolescent girls designed to improve confidence, positive self-concept, and develop a leadership skillset through five targeted aspects of leadership: growth mindset, integrity, resilience, love and loyalty, and strengths. Adolescence is a time when students are discovering who they are and shaping their identities. Girls decline in their self-confidence during adolescence due to fear of failure, …

Determining The Relationship Among Cattle Genotype, Hair Coat Score, And Productivity Through The Investigation Of Single Nucleotide Polymorphisms Within Prolactin, Dopamine Receptor D2, And Melatonin Receptor 1a, Erin Davis

Animal Science Undergraduate Honors Theses

Prolactin (PRL), melatonin (MTN), and dopamine (DA) are all hormones that are believed to play a role in the regulation and growth of hair in beef cattle. There are also single nucleotide polymorphisms associated with each of these hormones or their receptors, indicating that the investigation of these polymorphisms could allow them to serve as genetic markers for the future productivity of an animal. The objective of this study was to determine the relationships among cattle genotype, hair coat score, and productivity through the investigation of single nucleotide polymorphisms within prolactin, dopamine receptor D2, and melatonin receptor 1A. Body weights, …

The Diversity Of Terrestrial Mammals Surrounding Waterfall At Billy Barquedier National Park, Kelsey Johnson

Animal Science Undergraduate Honors Theses

Billy Barquedier is a National Park located in the Stann Creek district of Belize that contains Neotropical vegetation and wildlife. This study was performed in order to provide a baseline inventory and appearance frequency patterns of the terrestrial mammals located within Zone 1 of the park near a waterfall. The goal of the data and information collected during this study is to gain a greater understanding of the biodiversity and activity patterns of terrestrial mammals within the park and across Belize as a whole. The use of camera traps, small Sherman live traps, large live traps, and tracking methods were …

From Deviant Symbol To Cultural Icon? Understanding Pit Bull Stigma, Genevieve Minter

UNLV Theses, Dissertations, Professional Papers, and Capstones

This research draws from twelve months of ethnographic data using Las Vegas as a case study to understand how pit bull owners experience and negotiate stigma in various social settings. The human-dog relationship, long rooted in utility, transformed in the modern era as animals were promoted from worker to companion. The world’s first dog register, The American Kennel Club, created breed standards and encouraged selective breeding, which influenced the idea of certain dogs being more physically “dangerous” than others. Though the pit bull is not the first dog “breed” to be the object of discrimination, it is the first dog …