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Articles 1261 - 1290 of 13359
Full-Text Articles in Entire DC Network
Feminist Policy Analysis On Gender Mainstreaming Policy In Indonesian International Peacekeeping Forces, Zahra Ayu Kusuma Ricarvy, Sri Lestari Wahyuningroem
Feminist Policy Analysis On Gender Mainstreaming Policy In Indonesian International Peacekeeping Forces, Zahra Ayu Kusuma Ricarvy, Sri Lestari Wahyuningroem
Jurnal Politik
This study analyzes the implementation of gender mainstreaming policies within the Garuda troops using the Feminist Policy Analysis (FPA) approach in the context of Indonesia's commitment to gender equality in peacekeeping operations. Gender mainstreaming policies are expected to ensure equal access, participation, control, and benefits for both women and men within the defense system, as well as minimize gender discrimination. The method used in this research involves policy analysis as regulated in Presidential Instruction No. 9/2000, with a focus on its application in Peacekeeping Missions (IPM). Data were collected through interviews with relevant officials from the Ministry of Defense and …
Religious Stewardship And Pro-Environmental Action: The Mediating Roles Of Environmental Guilt And Anger, Shu Tian Ng, Kimin Eom
Religious Stewardship And Pro-Environmental Action: The Mediating Roles Of Environmental Guilt And Anger, Shu Tian Ng, Kimin Eom
Research Collection School of Social Sciences
Past research has found that stewardship belief can motivate pro-environmentalism among religious individuals. The present study investigates the emotional pathways linking religious stewardship belief and pro-environmental policy support. In an online experiment conducted with Christians in the United States (N = 604), we experimentally primed stewardship belief (N = 195) using a video that highlighted the human responsibility to care for God’s creations. We also included a control condition (N = 206) and a religion condition (N = 203), which presented a more generic religious message. As demonstrated in a mediation model, the stewardship manipulation (vs. …
Empowering Voices: Exploring The Career Trajectories Of Women Of Color Hr Professionals Amid Disruptive Change, Brandi R. Muñoz
Empowering Voices: Exploring The Career Trajectories Of Women Of Color Hr Professionals Amid Disruptive Change, Brandi R. Muñoz
Electronic Theses and Dissertations
This study investigated strategies to enhance diversity, equity, inclusion, and belonging initiatives in organizational leadership, focusing on supporting women of color in the workplace. The specific problem addressed was the underrepresentation and barriers faced by women of color in leadership positions despite their potential contributions to organizational success. The study employed a qualitative approach, combining qualitative interviews with socioeconomic data analysis. Data collection methods included semistructured interviews with women of color and a survey to gather demographic and employment information. The sample consisted of 16 women of color human resource professionals working in various industries and organizational settings across the …
Negative Work-To-Family Spillover Stress And Heightened Cardiovascular Risk Biomarkers In Midlife And Older Adults, Andree Hartanto, K.T.A.Sandeeshwara Kasturiratna, Meilan Hu, Shu Fen Diong, Verity Y. Q. Lua
Negative Work-To-Family Spillover Stress And Heightened Cardiovascular Risk Biomarkers In Midlife And Older Adults, Andree Hartanto, K.T.A.Sandeeshwara Kasturiratna, Meilan Hu, Shu Fen Diong, Verity Y. Q. Lua
Research Collection School of Social Sciences
Objectives: The current study aimed to investigate the health implications of negative work-to-family spillover on cardiovascular risk biomarkers. Methods: In a large-scale cross-sectional dataset of working or self-employed midlife and older adults in the United States (N = 1179), we examined five biomarkers linked to cardiovascular risk, including high-density lipoprotein (HDL) cholesterol, low-density lipoprotein cholesterol, triglyceride, interleukin-6, and C-reactive protein. Negative work-to-family spillover, measured using a four-item self-reported questionnaire, was included into our model to study its association with these cardiovascular risk biomarkers. Results: Our findings indicate a significant association between negative work-to-family spillover and cardiovascular risk biomarkers – higher …
Causal Influence Of Linguistic Learning On Perceptual And Conceptual Processing: A Brain-Constrained Deep Neural Network Study Of Proper Names And Category Terms, Phuc T U Nguyen, Malte R Henningsen-Schomers, Friedemann Pulvermüller
Causal Influence Of Linguistic Learning On Perceptual And Conceptual Processing: A Brain-Constrained Deep Neural Network Study Of Proper Names And Category Terms, Phuc T U Nguyen, Malte R Henningsen-Schomers, Friedemann Pulvermüller
Faculty, Staff and Student Publications
Language influences cognitive and conceptual processing, but the mechanisms through which such causal effects are realized in the human brain remain unknown. Here, we use a brain-constrained deep neural network model of category formation and symbol learning and analyze the emergent model's internal mechanisms at the neural circuit level. In one set of simulations, the network was presented with similar patterns of neural activity indexing instances of objects and actions belonging to the same categories. Biologically realistic Hebbian learning led to the formation of instance-specific neurons distributed across multiple areas of the network, and, in addition, to cell assembly circuits …
Place-Based Research At Local Scales, Laura Barbas Rhoden, Jennifer L. Bradham, Grace Schwartz
Place-Based Research At Local Scales, Laura Barbas Rhoden, Jennifer L. Bradham, Grace Schwartz
Community Based Research
No abstract provided.
Perceptions Of Financial Exploitation Among Older African American Women In The Black Church, Patricia Jackson
Perceptions Of Financial Exploitation Among Older African American Women In The Black Church, Patricia Jackson
Walden Dissertations and Doctoral Studies
Perceptions of Financial Exploitation Among Older African American Women in the Black Church by Patricia Jackson MS, Walden University, 2016 BA, Langston University, 1977 Dissertation Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy Social and Behavioral Sciences, Family Studies and Intervention Walden University February 2024
The Effectiveness Of Counseling Juveniles And Guardians As A Measure Of Recidivism, Robert D. Johnson
The Effectiveness Of Counseling Juveniles And Guardians As A Measure Of Recidivism, Robert D. Johnson
Walden Dissertations and Doctoral Studies
This study explored the lived experiences and perceptions of 10 juvenile justice professionals who had interacted with juvenile offenders and their guardians. This phenomenological qualitative study aimed to examine the outcomes of functional family therapy (FFT) between juvenile offenders and their guardians and their impact on recidivism rates in the National Capital Region portion of the Washington Metropolitan area. The theoretical framework that guided this study was FFT, which focuses on family dynamics and interactions while addressing a youth’s problem behavior. During semi-structured interviews (conducted via Zoom (due to COVID-19 restrictions), participants were asked open-ended questions about their feelings, experiences, …
The Impact Of Social Exclusion On Anticipatory Attentional Processing, John E. Kiat, Jacob E. Cheadle, Bridget J. Goosby
The Impact Of Social Exclusion On Anticipatory Attentional Processing, John E. Kiat, Jacob E. Cheadle, Bridget J. Goosby
Department of Sociology: Faculty Publications
The importance of understanding how we anticipate and prepare for social rejection is underscored by the mental and physical toll of continual social vigilance. In this study, we investigate the impact of social rejection on anticipatory attentional processes using the well-known Cyberball task, a paradigm in which participants engage in a game of catch with virtual avatars who after an initial period of fair-play (inclusion condition) then exclude the participant from the game (exclusion condition). The degree of anticipatory attention allocated by subjects towards the avatars was assessed by measuring P3b responses towards the avatars’ preparatory actions (i.e. the phase …
Intersecting Identities And Adjustment To The Primary-Secondary School Transition: An Integrative Review, Joanne Harris, Rebecca Nowland, Megan Todd
Intersecting Identities And Adjustment To The Primary-Secondary School Transition: An Integrative Review, Joanne Harris, Rebecca Nowland, Megan Todd
Journal of Educational Research and Practice
The primary-to-secondary school transition is a milestone for children because of the multiple changes they must navigate. Although most adjust successfully, approximately 30% of children have difficulties during this transition. Intersecting identities are also likely to influence how children navigate the adjustment of the school transfer, but there have been no syntheses of existing evidence relating to the impacts of intersectionality. We conducted an integrative review using eight databases (Education database, ERIC, ProQuest Education, PsychInfo, Scopus, SocIndex, Sociology Database, and Web of Science) and searched for quantitative or qualitative studies that examined how intersecting identities impact children’s self-concept, mental health, …
Calming The Body, Calming The Mind: A Pilot Study On The Use Of Zero Balancing To Reduce Anxiety, Misty L. Rhoads, Mary Murphy
Calming The Body, Calming The Mind: A Pilot Study On The Use Of Zero Balancing To Reduce Anxiety, Misty L. Rhoads, Mary Murphy
Journal of Transformative Touch
Background: The predominance of anxiety is currently at record levels, and the need for non-pharmaceutical approaches to help alleviate and decrease the harmful effects of anxiety on an individual and collective level is necessary. This study explored how Zero Balancing supports individuals with anxiety to manage their physical, mental, and emotional health more effectively. Researchers hypothesized that Zero Balancing would lower the perceived severity of general anxiety and lower perceived anxiety symptoms.
Methods: To honor the holistic nature of bodywork and the participants' lived experiences, the researchers utilized a concurrent mixed-methods phenomenological research design. Each participant received one Zero Balancing …
Thematic Analysis Through Artificial Intelligence (Ai), Prokopis A. Christou Phd
Thematic Analysis Through Artificial Intelligence (Ai), Prokopis A. Christou Phd
The Qualitative Report
Thematic analysis, a well-enforced qualitative analytic method, is likely to continue evolving with the adoption of AI technologies. This how-to report does not delve into the details of thematic analysis itself, as there are ample existing studies on the topic. Instead, it acknowledges the potential impacts, dynamics, and pitfalls of AI in thematic analysis while offering valuable advice, particularly for novice analysts, on how to incorporate and document AI tools in each phase of a thematic analysis. The author underscores the importance of not allowing AI to overshadow the analyst's critical evaluative and interpretive skills but instead supporting the use …
Redefining Disproportionate Arrest Rates: An Exploratory Quasi-Experiment That Reassesses The Role Of Skin Tone, Soren G. Brockdorf
Redefining Disproportionate Arrest Rates: An Exploratory Quasi-Experiment That Reassesses The Role Of Skin Tone, Soren G. Brockdorf
Doctoral Dissertations and Projects
The New York Times reported that Black Lives Matter was the third most-read subject of 2020. These articles brought to the forefront the question of disparity in arrest rates for darker-skinned people. Questioning arrest disparity is understandable because virtually everything known about disproportionate arrest rates has been a guess, and virtually all prior research on disproportionate arrest rates is questionable because of improper benchmarking (the denominator effect). Current research has highlighted the need to switch from demographic data to skin tone data and start over on disproportionate arrest rate research; therefore, this study explored the relationship between skin tone and …
Real-World Trends, Rural-Urban Differences, And Socioeconomic Disparities In Utilization Of Narrow Versus Broad Next-Generation Sequencing Panels, Yiqing Zhao, Anastasios Dimou, Zachary C Fogarty, Jun Jiang, Hongfang Liu, William B Wong, Chen Wang
Real-World Trends, Rural-Urban Differences, And Socioeconomic Disparities In Utilization Of Narrow Versus Broad Next-Generation Sequencing Panels, Yiqing Zhao, Anastasios Dimou, Zachary C Fogarty, Jun Jiang, Hongfang Liu, William B Wong, Chen Wang
Faculty, Staff and Student Publications
UNLABELLED: Advances in genetic technology have led to the increasing use of genomic panels in precision oncology practice, with panels ranging from a couple to hundreds of genes. However, the clinical utilization and utility of oncology genomic panels, especially among vulnerable populations, is unclear. We examined the association of panel size with socioeconomic status and clinical trial matching. We retrospectively identified 9,886 eligible adult subjects in the Mayo Clinic Health System who underwent genomic testing between January 1, 2016 and June 30, 2020. Patient data were retrieved from structured and unstructured data sources of institutional collections, including cancer registries, clinical …
The Potential Of Ethiopian Medicinal Plants To Treat Emergent Viral Diseases, Mekbib Fekadu, Ermias Lulekal, Solomon Tesfaye, Morgan Ruelle, Nigist Asfaw, Tesfaye Awas, Kebu Balemie, Kaleab Asres, Sebastian Guenther, Zemede Asfaw, Sebsebe Demissew
The Potential Of Ethiopian Medicinal Plants To Treat Emergent Viral Diseases, Mekbib Fekadu, Ermias Lulekal, Solomon Tesfaye, Morgan Ruelle, Nigist Asfaw, Tesfaye Awas, Kebu Balemie, Kaleab Asres, Sebastian Guenther, Zemede Asfaw, Sebsebe Demissew
Sustainability and Social Justice
Ethiopians have deep-rooted traditions of using plants to treat ailments affecting humans and domesticated animals. Approximately 80% of the population continues to rely on traditional medicine, including for the prevention and treatment of viral diseases. Many antiviral plants are available to and widely used by communities in areas where access to conventional healthcare systems is limited. In some cases, pharmacological studies also confirm the potent antiviral properties of Ethiopian plants. Building on traditional knowledge of medicinal plants and testing their antiviral properties may help to expand options to address the global pandemic of COVID-19 including its recently isolated virulent variants …
Beyond ‘Heightism’ And ‘Height Premium’: An Anthropology And Sociology Of Human Stature, Gideon Lasco
Beyond ‘Heightism’ And ‘Height Premium’: An Anthropology And Sociology Of Human Stature, Gideon Lasco
Development Studies Faculty Publications
This review article examines the meanings and materialities of human stature, from serving as a marker of human difference to shaping the socio-spatial experiences of individuals. I introduce existing perspectives on height from various disciplines, including biomedical discourses on the factors (e.g. nutrition, genetics) that determine height, economic discourses on how the average heights of populations have changed over time, sociobiological and psychological discourses that assume a pre-cultural, evolutionary “height premium”, and popular discourses on heightism and height discrimination. Drawing from a diverse range of scholarship since Saul Feldman called for a “sociology of stature” in the 1970s, I then …
Interracial Instagram: Depictions Of Interracial Couples On Instagram, Christie Sillo
Interracial Instagram: Depictions Of Interracial Couples On Instagram, Christie Sillo
Dissertations, Theses, and Capstone Projects
This dissertation examines depictions of interracial romantic relationships on Instagram, a popular photo- and video-sharing social networking site. Social networking sites like Instagram, whereby users connect with each other by creating, sharing, and consuming content, are prime sites for sociological study because ideas are constantly being (re)made on them. On Instagram, meaning-making is mainly done through the construction of a profile and the posting of images and/or videos. Using a mixed-methods research design of hashtag analysis, digital ethnography, discourse and image analysis, I critically analyze Instagram profiles that depict interracial romantic relationships. In doing so, I develop a contemporary, social …
Containerization Of Seafarers In The International Shipping Industry: Contemporary Seamanship, Maritime Social Infrastructures, And Mobility Politics Of Global Logistics, Liang Wu
Dissertations, Theses, and Capstone Projects
This dissertation discusses the mobility politics of container shipping and argues that technological development, political-economic order, and social infrastructure co-produce one another. Containerization, the use of standardized containers to carry cargo across modes of transportation that is said to have revolutionized and globalized international trade since the late 1950s, has served to expand and extend the power of international coalitions of states and corporations to control the movements of commodities (shipments) and labor (seafarers). The advent and development of containerization was driven by a sociotechnical imaginary and international social contract of seamless shipping and cargo flows. In practice, this liberal, …
Algorithmic Love: Twenty-First Century Organizations Of The Romantic, Sandra Moyano Ariza
Algorithmic Love: Twenty-First Century Organizations Of The Romantic, Sandra Moyano Ariza
Dissertations, Theses, and Capstone Projects
This dissertation investigates the highly computed and accelerated experiences of digital love as well as their cultural and artistic representations in order to shed light on the human and more-than-human entanglements producing the algorithmic love experience. The recent turn to love in critical theory and cultural studies examines how love circulates in neoliberal societies and in the subjective processes of the users, foregrounding the control of populations and the very much lamented “end of love” (Illouz 2019). My study of love supplements the neoliberalist critique of algorithmic love with a posthuman and media theory approach that attends to the material …
Critical-Race Elementary Schooling: Critical-Race Teacher Change Agents Are Challenging Whiteness In Elementary Schools, David R. Rosas
Critical-Race Elementary Schooling: Critical-Race Teacher Change Agents Are Challenging Whiteness In Elementary Schools, David R. Rosas
Dissertations, Theses, and Capstone Projects
Children in elementary schools think, talk, and reason in big ways that reflect how they live and experience race, racism, and racialization. Some elementary school teachers -- or critical-race teacher change agents -- intentionally include this work in their classrooms. My aim is to find out what motivates critical-race teacher change agents to challenge Whiteness in their classrooms and understand what they say they do to challenge Whiteness with young children.
An emphasis on racial-justice work in elementary schools has often been overlooked by teacher education and has been further pushed back by the recent backlash on critical race theory …
Frameworks For Measuring Population Health: A Scoping Review, Sze Ling Chan, Clement Zhong Hao Ho, Nang Ei Ei Khaing, Ezra Ho, Candelyn Pong, Jia Sheng Guan, Calida Chua, Zongbin Li, Trudi Lim Wenqi, Sean Shao Wei Lam, Lian Leng Low, Choon How How
Frameworks For Measuring Population Health: A Scoping Review, Sze Ling Chan, Clement Zhong Hao Ho, Nang Ei Ei Khaing, Ezra Ho, Candelyn Pong, Jia Sheng Guan, Calida Chua, Zongbin Li, Trudi Lim Wenqi, Sean Shao Wei Lam, Lian Leng Low, Choon How How
Research Collection School Of Computing and Information Systems
Introduction Many regions in the world are using the population health approach and require a means to measure the health of their population of interest. Population health frameworks provide a theoretical grounding for conceptualization of population health and therefore a logical basis for selection of indicators. The aim of this scoping review was to provide an overview and summary of the characteristics of existing population health frameworks that have been used to conceptualize the measurement of population health. Methods We used the Population, Concept and Context (PCC) framework to define eligibility criteria of frameworks. We were interested in frameworks applicable …
From The Outside Looking In: Transmasculine Narrative Identity, Experiences, And Larger Narratives On Social Media, Micah Roldan
From The Outside Looking In: Transmasculine Narrative Identity, Experiences, And Larger Narratives On Social Media, Micah Roldan
Dissertations, Theses, and Capstone Projects
Narrative identity development is an essential process in how individuals perceive themselves and the world around them. Often, narrative identity is studied in cisgender heterosexual individuals and applied to others without the acknowledgment of individuals that fall outside of these categories. Drawing upon existing literature and autoethnography, this thesis aims to meaningfully bridge this gap by studying the narrative identity development of transmasculine individuals through the lens of social media. This thesis proposes that the use of social media to share gender transition journeys has created a new digital trans and queer narrative for users and viewers. This narrative is …
Making And Unmaking Multiethnic Black Neighborhoods: Immigration, Race, And Gentrification In New York And Paris, Maura Mcgee
Making And Unmaking Multiethnic Black Neighborhoods: Immigration, Race, And Gentrification In New York And Paris, Maura Mcgee
Dissertations, Theses, and Capstone Projects
This dissertation is a transatlantic comparative study of gentrification in multiethnic Black neighborhoods in New York and Paris. It draws on neighborhood case studies conducted in Crown Heights in Brooklyn and la Goutte d’Or in Paris, home respectively to African ancestry immigrant communities from the Caribbean and Sub-Saharan Africa. It looks specifically at the causes and consequences of changes in neighborhood social spaces—the commercial landscape and social institutions—rather than at shifts in residential patterns.
Three main questions guide this research. First, what roles do race and immigration play in the process of gentrification, which has historically been most prevalent in …
Examining The Influence Of Adult Mentors On Fostering Prosocial Behaviors Among Teens, John H. Weaver Iii
Examining The Influence Of Adult Mentors On Fostering Prosocial Behaviors Among Teens, John H. Weaver Iii
Electronic Theses and Dissertations
This dissertation addressed a critical public health concern stemming from the prevalence of antisocial behavior among U.S. teenagers. The study specifically tackled the lack of information regarding the components of an effective risk-reduction mentoring program for teens. The primary aim was to explore how young adult alums of a central Florida mentoring program articulated the influence of mentoring relationships that have shaped their attitudes and perceptions concerning prosocial behavior during adolescence. As a bounded qualitative case study, this research employed semistructured interviews with 11 young adult mentees from a mentoring program. Additionally, a focus group of five adult mentors who …
Sex-Specific Disparities In Covid-19 Outcomes, Zubaid Rafique, Valerie Durkalski-Mauldin, William F Peacock, Kabir Yadav, Joshua C Reynolds, Clifton W Callaway
Sex-Specific Disparities In Covid-19 Outcomes, Zubaid Rafique, Valerie Durkalski-Mauldin, William F Peacock, Kabir Yadav, Joshua C Reynolds, Clifton W Callaway
Faculty, Staff and Students Publications
OBJECTIVES: Sex-specific disparities in morbidity and mortality of COVID-19 illness are not well understood. Neutralizing antibodies (Ab) may protect against severe COVID-19 illness. We investigated the association of sex with disease progression and SARS-CoV-2 Ab response.
METHODS: In this exploratory analysis of the phase 3, multicenter, randomized, placebo-controlled Convalescent Plasma in Outpatients (C3PO) trial, we examined whether sex was associated with progression to severe illness, defined as a composite of all-cause hospitalization, emergency/urgent care visit, or death within 15 days from study enrollment. Patients had a positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) test, symptom onset within 7 days, …
Digital Echoes: The Influence Of Internet And Social Media On The “Ideal” Conception Of Motherhood In Indonesian Stunting Programs, Sari Damar Ratri
Digital Echoes: The Influence Of Internet And Social Media On The “Ideal” Conception Of Motherhood In Indonesian Stunting Programs, Sari Damar Ratri
Masyarakat: Jurnal Sosiologi
This article examines how information about childhood care available on social media affects the construction of ideal Indonesian mothers. Specifically, I pay closer attention to how women's roles and experiences in stunting prevention campaigns are portrayed and enacted online in the context of the digital socialization of these programs. Based on online ethnographic research from 2021-2023, which examined social media accounts of healthcare professionals and mothers, this article explores the construction of “ideal” motherhood within the digital realm of stunting programs. As health care professionals’ social media accounts carried messages and embodied the authoritative power of medical knowledge, they helped …
Biosocial Criminology: Projected Criminal Behaviors Induced By Climate Changes, David Brown Sr.
Biosocial Criminology: Projected Criminal Behaviors Induced By Climate Changes, David Brown Sr.
Walden Dissertations and Doctoral Studies
No abstract provided.
Asosiasi Jaminan Sosial Dengan Partisipasi Kerja Penduduk Lansia Di Indonesia, Evelyn Fairuz Wibowo, Dwini Handayani
Asosiasi Jaminan Sosial Dengan Partisipasi Kerja Penduduk Lansia Di Indonesia, Evelyn Fairuz Wibowo, Dwini Handayani
Jurnal Ekonomi Kependudukan dan Keluarga
Indonesia has entered a period of aging population. The number of elderly people has increased sharply without social security ownership, making the elderly population vulnerable to poverty. Financial demands make the elderly must continue to work in their old age, even though their biological and psychological conditions are declining. The study aims to analyzes the effect of social insurance (pension insurance and health insurance) on the work participation of the elderly population which is controlled based on individual, household, and social characteristics. Using secondary data from the 2020 National Socioeconomic Survey and analyzed using logistic biner regression, this …
Immune Profiling In Puerto Rican Injection Drug Users With And Without Hiv-1 Infection, Sydney J. Bennett, Carmen Ana Davila, Zahiraliz Reyes, Aníbal Valentín-Acevedo, Kim Gocchi Carrasco, Roberto Abadie, M. Caleb Marlin, Marci Beel, Andrew G. Chapple, Samodha C. Fernando, Joel M. Guthridge, Kathy S. Chiou, Kirk Kirk, John T. West, Charles Wood
Immune Profiling In Puerto Rican Injection Drug Users With And Without Hiv-1 Infection, Sydney J. Bennett, Carmen Ana Davila, Zahiraliz Reyes, Aníbal Valentín-Acevedo, Kim Gocchi Carrasco, Roberto Abadie, M. Caleb Marlin, Marci Beel, Andrew G. Chapple, Samodha C. Fernando, Joel M. Guthridge, Kathy S. Chiou, Kirk Kirk, John T. West, Charles Wood
Department of Sociology: Faculty Publications
Antiretroviral therapy has been effective in suppressing HIV viral load and enabling people living with HIV to experience longer, more conventional lives. However, as people living with HIV are living longer, they are developing aging-related diseases prematurely and are more susceptible to comorbidities that have been linked to chronic inflammation. Coincident with HIV infection and aging, drug abuse has also been independently associated with gut dysbiosis, microbial translocation, and inflammation. Here, we hypothesized that injection drug use would exacerbate HIV-induced immune activation and inflammation, thereby intensifying immune dysfunction. We recruited 50 individuals not using injection drugs (36/50 HIV+) …
Personalized Trial Ethics And Institutional Review Board Submissions, Joyce P Samuel, Susan H Wootton
Personalized Trial Ethics And Institutional Review Board Submissions, Joyce P Samuel, Susan H Wootton
Faculty, Staff and Student Publications
The ethical and regulatory oversight of any clinical activity related to human subjects is commonly determined based on its categorization as either clinical practice or research. Prominent bioethicists have criticized the traditional distinctions used to delineate these categories, calling them counterproductive and outmoded, and arguing that learning and clinical practice should be deliberately and appropriately integrated. Personalized trials represent a clinical activity with characteristics that overlap both categories, making ethical and regulatory oversight requirements less straightforward. When the primary intent of the personalized trial is to assist in the conduct of individualized patient care with an emphasis on protecting the …