Digital Commons Network^™

Identifying Risk Factors For Disparities In Breast Cancer Mortality Among African-American And Hispanic Women, Nancy Tian, Pierre Goovaerts, F. Benjamin Zhan, T. Edwin Chow, Jeff Gaines Wilson

School of Earth, Environmental, & Marine Sciences Faculty Publications

Background: This study evaluated the risk factors associated with racial disparities in female breast cancer mortality for African-American and Hispanic women at the census tract level in Texas from 1995 to 2005.

Methods: Data on female breast cancer cases were obtained from the Texas Cancer Registry. Socioeconomic and demographic data were collected from Census 2000. Network distance and driving times to mammography facilities were estimated using Geographic Information System techniques. Demographic, poverty and spatial accessibility factors were constructed using principal component analysis. Logistic regression models were developed to predict the census tracts with significant racial disparities in breast cancer mortality …

Recreational Music-Making In Music Pedagogy: A Manifesto For Change, Brandon Keith Wood

Theses and Dissertations--Music

The arts are an essential part of any student’s well rounded education. The future of music in education will depend on its ability to deliver relevant, effective, and measurable outcomes. However, the expectations and performance nature of traditional curricula often foster a sense of musical elitism and ostracizes students that are solely interested in music as a recreational outlet. Incorporating recreational music-making into education can provide opportunities for students to experience self-expression, creativity, social connection, and enjoyment. These values will not only enhance their education, but also lead to acquired skills for use in all areas of their lives. Activities …

Are Low Wages Risk Factors For Hypertension?, J. Paul Leigh, Juan Du

Economics Faculty Publications

Objective: Socio-economic status (SES) is strongly correlated with hypertension. But SES has several components, including income and correlations in cross-sectional data need not imply SES is a risk factor. This study investigates whether wages-the largest category within income-are risk factors. Methods: We analysed longitudinal, nationally representative US data from four waves (1999, 2001, 2003 and 2005) of the Panel Study of Income Dynamics. The overall sample was restricted to employed persons age 25-65 years, n = 17 295. Separate subsamples were constructed of persons within two age groups (25-44 and 45-65 years) and genders. Hypertension incidence was self-reported based on …

An Analysis Of Laboratory Inspections At The University Of Kentucky, Rachel Eldridge

MPA/MPP/MPFM Capstone Projects

Recent news stories about laboratory accidents in which students were severely injured and killed have brought much-needed attention to lab safety. Creating a positive safety climate on college and university campuses is very important in reducing accidents. At the University of Kentucky, all laboratories are inspected once every year, and the results are recorded in a lab inspection database. These data include the department, building, lab classification, type of violation, room number, and the name of the PI (Principal Investigator). I want to analyze inspections to find out whether department and the lab classification are significant in looking at violations. …

Constrained Optimal Control For A Multi-Group Discrete Time Influenza Model, Paula Andrea Gonzalez Parra

Open Access Theses & Dissertations

During the last decades, mathematical epidemiological models have been used to understand the dynamics of infectious diseases and guide public health policy. In particular, several continuous models have been considered to study single in uenza outbreaks and the impact of dierent control policies. In this dissertation, a discrete time model is introduced in order to study optimal control strategies for in uenza transmission; since epidemiological data is collected on discrete units of time, a discrete formulation is more ecient. From a mathematical point of view, continuous time model are easier to analyze, however, the numerical solution of discrete-time models is …

Human Risk Of Infection With Borrelia Burgdorferi, The Lyme Disease Agent, In Eastern United States, Maria A. Diuk-Wasser, Anne Gatewood Hoen, Paul Cislo, Robert Brinkerhoff, Sarah A. Hamer, Michelle Rowland, Roberto Cortinas, Gwenaël Vourc’H, Forrest S. Melton, Graham J. Hickling, Jean I. Tsao, Jonas Bunikis, Alan G. Barbour, Uriel Kitron, Joseph Piesman, Durland Fish

Department of Entomology: Faculty Publications

The geographic pattern of human risk for infection with Borrelia burgdorferi sensu stricto, the tick-borne pathogen that causes Lyme disease, was mapped for the eastern United States. The map is based on standardized field sampling in 304 sites of the density of Ixodes scapularis host-seeking nymphs infected with B. burgdorferi, which is closely associated with human infection risk. Risk factors for the presence and density of infected nymphs were used to model a continuous 8 km × 8 km resolution predictive surface of human risk, including confidence intervals for each pixel. Discontinuous Lyme disease risk foci were identified in …

Synthesizing Parasitology With Archaeology In Paleopathology, Karl Reinhard, Adauto Araujo

Karl Reinhard Publications

Parasitology is the study of organisms that are symbiotic with other organisms. In this form of symbiosis, the parasite species by definition benefits from the interaction while the host is harmed to some degree. In actuality, some parasites benefit their hosts. The animals traditionally studied by parasitologists range from protozoa to arthropods, and include all types of internal and external worms. Ticks, fleas, lice, and a variety of insects that transmit parasites are also studied by parasitologists. Recently, a more holistic view of parasitism appeared, including bacteria and viruses. In essence, parasitology is the study of a certain kind of …

Prescient Human Fetuses Thrive, Curt A. Sandman, Elyssia Poggi Davis, Laura M. Glynn

Psychology Faculty Articles and Research

Fetal detection of adversity is a conserved trait that allows many species to adapt their early developmental trajectories to ensure survival. According to the fetal-programming model, exposure to stressful or hostile conditions in utero is associated with compromised development and a lifelong risk of adverse health outcomes. In a longitudinal study, we examined the consequences of prenatal and postnatal exposure to adversity for infant development. We found increased motor and mental development during the 1st year of life among infants whose mothers experienced congruent levels of depressive symptoms during and after pregnancy, even when the levels of symptoms were relatively …

Complexities In The Diagnosis And Treatment Of Thyroid Cancer: Discussions, Observations, Research And Public Policy, Hannah V. Gordon

CMC Senior Theses

The impact of the increasing incidence of thyroid cancer presents an interesting case study in public health policy and resource allocation. During the last three decades, thyroid cancer cases have increased by more than 400%. As an illness that affects the lives of hundreds of thousands each year, the human and economic costs will be magnified in the next decade. It is estimated that approximately 13-67% of people will have thyroid nodules during their life of which approximately 5% will be malignant. The standard treatment, a thyroidectomy frequently followed by radioactive 131 iodine treatment, accordingly would seem to be a …

Relationship Between Religiosity, Violent Behavior And Gang Activity In Economically Disadvantaged Adolescents, David Mckenzie

All ETDs from UAB

RELATIONSHIP BETWEEN RELIGIOSITY, VIOLENT BEHAVIOR AND GANG ACTIVITY AMONG ECONOMICALLY DISADVANTAGED ADOLESCENTS DAVID McKENZIE HEALTH EDUCATION & HEALTH PROMOTION ABSTRACT Few studies have examined the relationship between religiosity, violent behavior and gang activity in disadvantaged youth. This research study analyzed data from a population of low-income adolescents in Mobile, Alabama. The research objectives were to assess the relationship between adolescent religiosity and involvement in violent behavior and gang activity, and to determine if there were gender differences between boys and girls regarding religiosity, violent behavior and gang activity. It was hypothesized that there would be an inverse relationship between religiosity …

Centering Pregnancy And Adverse Pregnancy Outcome: An Evaluation Of Group Prenatal Care In A Rural Western Kentucky Clinic, Lorie Wayne Chesnut

All ETDs from UAB

CenteringPregnancySmiles [TM] (CPS), a group prenatal care program with an oral health component, has demonstrated promising results in urban communities with primarily low-income minority women. This study examined three questions: 1) Do women who participate in CPS have better birth outcomes than those who participate in traditional prenatal care, even after adjusting for maternal characteristics and risk factors? 2) Is level of exposure to the intervention associated with improved birth outcomes? 3) Do women with dental infection have an increased risk of poor birth outcomes? Data were abstracted from medical records and birth certificates. Birth outcomes for women enrolled in …

Trajectories Of Depressive Symptoms And Illicit Drug Use: Longitudinal Temporal Associations And Comorbidity In A Community Sample Of Adults, Yulia Khodneva

All ETDs from UAB

Cross-sectional studies of the community and treatment samples suggest substantial comorbidity between depression and illicit drug use disorders. Controversy exists whether such pattern of comorbidity is seen among drug using behaviors and depressive symptoms that fall short of the DSM-IV criteria for a clinical disorder. This dissertation research applied principles of the life course perspective and trajectory modeling to describe heterogeneity and comorbidity of subthreshold depressive symptoms with opioid, cocaine and amphetamine use in middle age. Secondary analysis of community-dwelling adults from the Coronary Artery Risk Development in Young Adults (CARDIA) study was performed. The CARDIA cohort, N=5115 at inception …

The Role Of Cd11c+ Cells In Response To Ozone, Jeffrey David Brand

All ETDs from UAB

Environmental ozone exposure remains a major public health concern with over one-third of the United States population experiencing unhealthful levels. Epidemiological studies indicate exposure increases morbidity in those with pre-existing disease such as asthma, though the biological mechanisms underlying this phenomenon remain elusive. CD11c+ cells within the respiratory tract include dendritic cells (DCs), which are the most efficient antigen presenters and play major roles controlling immune responses. In addition, DCs are thought necessary for asthma pathogenesis and exacerbation. Therefore the link between ozone associated asthma morbidity may be DCs. We hypothesize ozone exposure may site specifically alter DC phenotypes, numbers, …

The Hypometabolic Actions Of Hydrogen Sulfide In Mammalian Systems, Asaf Stein

All ETDs from UAB

In recent years, hydrogen sulfide (H2S) has been identified as a ubiquitous cell signaling molecule. In addition to its diverse physiological roles, H2S has emerged as a possible drug therapy, with a wide range of applications. Along with cytoprotective effects in pathological states such as ischemia-reperfusion injury, H2S has been shown to decrease aerobic metabolism in a reversible manner. This dissertation is focused on exploring H2S-induced hypometabolism and the implications therein for human health and disease. We have shown that rats exposed to 80 ppm H2S gas in combination with low oxygen (10.5% O2) for 6 hr exhibit decreases in …

The Impact Of Community Health Centers On Prostate Cancer Screening Behaviors Of African American Males: A Mixed Methods Study, Michael C. Taylor

All ETDs from UAB

THE IMPACT OF COMMUNITY HEALTH CENTERS ON PROSTATE CANCER SCREENING BEHAVIORS OF AFRICAN AMERICAN MALES: A MIXED METHODS STUDY MICHAEL C. TAYLOR UAB SCHOOL OF PUBLIC HEALTH DEPARTMENT OF HEALTH BEHAVIOR ABSTRACT Federally qualified community health centers have a significant impact upon uninsured and low income populations in the United States by providing low cost primary care and preventive services. The purpose of this mixed methods study was to determine the impact of community health centers (CHCs) on African American males' prostate cancer screening behavior in a major Southern city. A sequential explanatory mixed method model was used to assess …

Somatechnologies Of Body Size Modification: Posthuman Embodiment And Discourses Of Health, Meghan Griffin

Electronic Theses and Dissertations

This project focuses on persistent gaps in philosophies of the body: the enduring mindbody divide in accounts of phenomenology, the unfulfilled promises of representing and inhabiting the body in online and virtual spaces, and the difference between health as quantified in medical discourse versus health as lived experience. These tensions are brought to light through the electronic food journal genre where the difficulty in capturing pre-noetic, outsideconsciousness aspects of experience and embodied health are thrown into relief against circulating cultural discourses surrounding health, body size, self-surveillance, and self-care. The electronic food journal genre serves as a space for users to …

Workers Exposed To Metalworking Fluids: Evaluation Of Bioaerosol Exposure And Effects On Respiratory And Skin Health, Caroline Duchaine, Yvon Cormier, Yan Gilbert, Marc Veillette, Jacques Lavoie, Anne Mériaux, Christine Touzel, Denis Sasseville, Yves Poulin

Rapports de recherche scientifique

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Certains problèmes respiratoires sont observés chez les machinistes travaillant avec des fluides de coupe solubles (FC). Ces problèmes pourraient être reliés aux aérosols contenant des microorganismes présents dans les systèmes de FC. Pour mieux comprendre les effets de ces aérosols sur la santé humaine, l’environnement de travail doit être caractérisé. Nous avons détaillé la flore microbienne des FC ainsi que celle de l’air, les brouillards d’huile, les poussières inhalables et les endotoxines de 44 sites d’usinage répartis dans 25 usines du Québec. La PCR quantitative a été utilisée afin de dénombrer …

Occupational Health And Safety Of Students Who Hold Jobs During The School Year: Effects Of Concurrent School Activity And Work Constraints, Luc Laberge, Élise Ledoux, Chloé Thuilier, Michaël Gaudreault, Jeanne-Sophie Martin, Esther Cloutier, Julie Auclair, Lise Lachance, Suzanne Veillette, Claude Rozon, Marco Gaudreault, Nadine Arbour, Sandra Bescou, Thomas Agenais, Laurence Hostiou

Rapports de recherche scientifique

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Cette recherche s'inscrit dans la foulée des travaux publiés au Québec depuis les années 1990 qui ont contribué à l'émergence d'un nouveau champ de recherche sur le travail rémunéré chez les étudiants. Ces travaux s'intéressent plus particulièrement à l'incidence du travail rémunéré sur les études. Cependant, rares sont ceux qui ont directement abordé les atteintes potentielles à la santé en lien avec le travail rémunéré des étudiants, notamment les accidents de travail, les troubles musculo-squelettiques (TMS), la détresse psychologique et la fatigue.

Bien que les étudiants travailleurs soient moins à risque …

Evaluation Of Beryllium Toxicity According To Chemical Form And Particle Size, Caroline Muller, Bruce Mazer, Fariba Salehi, Séverine Audusseau, Ginette Truchon, Jean Lambert, Gilles L Espérance, Gaston Chevalier, Suzanne Philippe, Yves Cloutier, Pierre Larivière, Joseph Zayed

Rapports de recherche scientifique

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Au cours des dernières années, plusieurs auteurs ont remis en cause le niveau de protection accordé aux travailleurs par la valeur seuil reconnue pour le béryllium (Be) et ses sels (VEMP Québec, TLV (TWA) ACGIH). La prévalence des effets associés au Be suggère que les risques sont en fonction de sa spéciation. Par ailleurs, il semble que les particules fines constituent la fraction d’intérêt pour l’occurrence de tels effets. L’objectif de cette recherche est d’évaluer la toxicité du Be en fonction de la forme chimique et de la taille particulaire.

Pour …

Effects Of Concentration Peaks On Styrene Neuroxicity In The Fibreglass Reinfoced Plastics Industry. Phase Ii, Adolf Vyskocil, Naïma El Majidi, Ross Thuot, Charles Beaudry, Ginette Charest-Tardif, Robert Tardif, France Gagnon, Bernadette Ska, Alice Turcot, Daniel Drolet, Elmira Aliyeva, Claude Viau

Rapports de recherche scientifique

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D’abord, une analogie

Pour bien expliquer l’objet de ce projet de recherche, nous allons d’abord recourir à une analogie. Supposons deux personnes de même poids qui sont invitées chez des amis. À midi, leur hôte débouche une bouteille de vin et leur offre à boire. La première personne commence à consommer très lentement de sorte qu’à huit heures du soir, elle a bu la moitié de la bouteille. La seconde personne commence à boire à sept heures trente du soir et avale donc aussi une demi-bouteille, mais d’un seul trait. Leur …

Effect Of Chemical Substances On Hearing: Interactions With Noise, Adolf Vyskocil, Tony Leroux, Ginette Truchon, François Lemay, France Gagnon, Martine Gendron, Amar Boudjerida, Naïma El-Majidi, Claude Viau

Rapports de recherche scientifique

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Les auteurs ont examiné l’effet combiné du bruit et de l’exposition à des substances chimiques sur l’audition en utilisant des données humaines et animales de la littérature scientifique. Ils constatent qu’il n’existe qu’une cinquantaine d’études dans lesquelles l’exposition tant au bruit qu’aux substances chimiques est caractérisée avec suffisamment de précision et de fiabilité. De plus, les définitions données à une exposition au bruit « forte » ou « faible » varient d’une étude à l’autre. Il en résulte qu’il est très difficile de combiner l’ensemble des données pour en tirer des …

Perceived Partner Support In Pregnancy Predicts Lower Maternal And Infant Distress, Lynlee R. Tanner Stapleton, Christine Dunkel Schetter, Erika Westling, Christine Rini, Laura M. Glynn, Calvin J. Hobel, Curt A. Sandman

Psychology Faculty Articles and Research

Maternal postpartum emotional distress is quite common and can pose significant risk to mothers and infants. The current study investigated mothers' relationships with their partners during pregnancy and tested the hypotheses that perception of prenatal partner support is a significant predictor of changes in maternal emotional distress from midpregnancy to postpartum, and contributes to maternal ratings of infant distress to novelty. Using a prospective longitudinal design, 272 adult pregnant women were interviewed regarding their partner support, relationship satisfaction, and interpersonal security (attachment style and willingness to seek out support), and they completed standardized measures of prenatal symptoms of depression and …

Cervical Human Papillomavirus Infection Among Young Women Engaged In Sex Work In Phnom Penh, Cambodia: Prevalence, Genotypes, Risk Factors And Association With Hiv Infection, Marie-Claude Couture, Kimberly Page, Ellen S. Stein, Neth Sansothy, Keo Sichan, John Kaldor, Jennifer L. Evans, Lisa Maher, Joel Palefsky

Nursing and Health Professions Faculty Research and Publications

Background

Although cervical cancer is the leading cancer in Cambodia, most women receive no routine screening for cervical cancer and few treatment options exist. Moreover, nothing is known regarding the prevalence of cervical HPV or the genotypes present among women in the country. Young sexually active women, especially those with multiple sex partners are at highest risk of HPV infection. We examine the prevalence and genotypes of cervical HPV, as well as the associated risk factors among young women engaged in sex work in Phnom Penh, Cambodia.

Methods

We conducted a cross-sectional study among 220 young women (15–29 years) engaged …

A Community Dietetics Intervention To Improve The Use Of Oral Nutritional Supplements In The Community Setting, Sharon Kennelly

Doctoral

Evaluation of a community dietetics intervention to improve oral nutritional supplement prescribing practices in the community. Background: Healthcare professionals working in the community do not always prescribe oral nutritional supplements (ONS) according to best practice guidelines and expenditure on ONS has increased. The aim of this study was to investigate ONS prescribing practices and to determine the impact of a community dietetics intervention on these practices and expenditure one year later. Methods: At baseline ONS prescribing practices were investigated by patient interview with a community dietitian. The intervention involved an education programme for general medical practitioners (GPs), practice nurses, nurses …

Distribution/Localization And Relative Quantitation Of C-Terminal Αa-Crystallin Truncation Products Within Lenses Of Icr/F Rats Treated With Dietary Supplemented Genistein, Kyle Anthony Floyd

All ETDs from UAB

The ocular lens functions to focus light coming into the eye onto the retina. Lens development begins in utero, and continues over an individual's lifetime. Lens fiber cells and their proteins are only synthesized once and have no repair mechanisms, so they remain for an individual's lifetime. The α-crystallins, the most abundant lens proteins, act as chaperones to keep damaged/unfolded proteins in-solution. Cataract disease is associated with protein damage, leading to a light scattering opacity. It has been suggested that truncation of αA-crystallin leads to a loss of chaperone function. Cataract disease is the leading cause of blindness in the …

Predictors Of Vaginal Douching Behavior And Sexual Risk Taking Among A Population Of Women In The South: The Influence Of Sexual Concurrency And Partner Incarceration, Keri J. Griffin

All ETDs from UAB

In the United States, adolescent women between the ages of 14 and 19 are estimated to bear the largest burden of sexually transmitted infections. Left untreated, these infections have the potential to result in several adverse reproductive health outcomes. Sexually risky behaviors, including early sexual initiation, sexual partner concurrency, and the use of vaginal douche products increase the risk for the contraction of sexually transmitted infections. Further, having a sexual relationship with a male partner who is known to have other partners or a history of contact with the justice system might put a woman at additional risk. Utilizing a …

Measuring Disease Activity And Use Of Complementary And Alternative Medicine In African-Americans With Rheumatoid Arthritis, Ashutosh Tamhane

All ETDs from UAB

The aims of this project were to: 1) compare disease activity scores 28 joints (DAS28) based on erythrocyte sedimentation rate (ESR) versus that based on C-reactive protein (CRP), and 2) describe prevalence of complementary and alternative medicine (CAM) use and examine differences of CAM use stratified by disease duration and sex. This analysis included participants from the Consortium for the Longitudinal Evaluation of African Americans with Early Rheumatoid Arthritis (CLEAR) Registry. Using tender and swollen joint counts separate ESR-based and CRP-based DAS28 scores (DAS28-ESR3 and DAS28-CRP3) were calculated, as were DAS28-ESR4 and DAS28-CRP4, which included the patient¡¯s assessment of disease …

Sleep Duration And Obesity: Longitudinal Study Of Adolescents, Herpreet Kaur Thind

All ETDs from UAB

Prevalence of obesity continues to be high in the United States with about one-third adults being overweight or obese. Among adolescents the rates of overweight/obesity have increased by three times in the past two decades. Moreover, the rates of obesity are disproportionately high among the minority population. Recently, sleep duration has emerged as an independent risk factor for obesity. Several cross-sectional and longitudinal studies worldwide have shown an inverse relationship between sleep duration and obesity. However, some studies do not support this association. Majority of the studies in the United States have been conducted on predominantly White populations. African Americans …

Application Of The Social Cognitive Theory To A Web-Based Physical Activity Intervention For Overweight African American Female College Students, Rodney Joseph

All ETDs from UAB

Background.African American women report low levels of physical activity and share a disproportionate burden of many health conditions associated with being insufficiently active, indicating the need for innovative approaches to promote physical activity in this population. The purpose of the current study was to evaluate changes in physical activity and associated Social Cognitive Theory constructs of outcome expectations, enjoyment, self-regulation, and social support following the completion of a six month, culturally-adapted, Social Cognitive Theory-based website-delivered weight loss and physical activity intervention for young African-American women. Methods.A secondary data analysis was performed on African-American female college students (N=34) enrolled in a …

Association Between Cc Chemokine Ligand 3-Like-1 (Ccl3l1) Gene Copy Number And Rheumatoid Arthritis In African Americans, Mawuli Kwame Nyaku

All ETDs from UAB

Gene copy number of the CC Chemokine ligand 3-Like-1 (CCL3L1) located on chromosome 17 position q12 varies between ethnicities. Previously, gene copy number of CCL3L1 greater than the ethnic median copy has been associated with an increased risk of Rheumatoid Arthritis. Three later studies found no association between CCL3L1 and RA. All studies were conducted in non-African Americans and an objective of this study was to determine this association in an African American cohort. CCL3L1 shares significant homology with three other genes within the same cluster; CC Chemokine ligand 3 (CCL3), CC Chemokine ligand 3-Like-2 (CCL3L2) and CC Chemokine ligand …