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Pathogenic Policy: Health-Related Consequences Of Immigrant Policing In Atlanta, Ga, Nolan Sean Kline
Pathogenic Policy: Health-Related Consequences Of Immigrant Policing In Atlanta, Ga, Nolan Sean Kline
USF Tampa Graduate Theses and Dissertations
Multilayered immigration enforcement regimes comprising state and federal statutes and local police practices demand research on their social and health-related consequences. This dissertation explores the multiple impacts of immigrant policing: sets of laws and police activities that make undocumented immigrants more visible to authorities and increase their risk of deportation. Examining immigrant policing through a multi-sited framework and drawing from principles of engaged anthropology, findings from this dissertation suggest how immigrant policing impacts undocumented immigrants' overall wellbeing, health providers' professional practice, and reveals troubles with safety net medical care. Interviews and participant observation experiences suggest how immigrant policing perpetuates a …
Hpv Vaccine Decision-Making Among Male Sexual Minorities: An Integrative Theoretical Framework For Vaccine Promotion, Christopher W. Wheldon
Hpv Vaccine Decision-Making Among Male Sexual Minorities: An Integrative Theoretical Framework For Vaccine Promotion, Christopher W. Wheldon
USF Tampa Graduate Theses and Dissertations
Men who have sex with men (MSM) are at increased risk of anal cancer as a result of anal HPV infection. Routine HPV vaccination is recommended for all MSM up through age 26; however, vaccine uptake among this population is low. The Integrative Model of Behavioral Prediction (IM) was used to identify, describe, and explain psychosocial factors related to HPV vaccine decision-making for young MSM. A sequential mixed-methods approach consisting of semi-structured interviews, a quantitative survey, and a qualitative open-ended survey was used to address the following aims: (1) Determine salient outcome, normative, efficacy, and control beliefs related to HPV-vaccination …
Exploring Social Networking Technologies As Tools For Hiv Prevention For Men Who Have Sex With Men, Jorge Ramallo, Thomas Kidder, Tashuna Albritton, Gary Blick, John Pachankis, Valen Grandeleski, Trace Kershaw
Exploring Social Networking Technologies As Tools For Hiv Prevention For Men Who Have Sex With Men, Jorge Ramallo, Thomas Kidder, Tashuna Albritton, Gary Blick, John Pachankis, Valen Grandeleski, Trace Kershaw
Publications and Research
Social networking technologies are influential among men who have sex with men (MSM) and may be an important strategy for HIV prevention. We conducted focus groups with HIV positive and negative participants. Almost all participants used social networking sites to meet new friends and sexual partners. The main obstacle to effective HIV prevention campaigns in social networking platforms was stigmatization based on homosexuality as well as HIV status. Persistent stigma associated with HIV status and disclosure was cited as a top reason for avoiding HIV-related conversations while meeting new partners using social technologies. Further, social networking sites have different social …
Sociodemographic Predictors Of Medication Nonadherence Among Latinos Diagnosed With Diabetes Type Ii, Bianca L. Tristan
Sociodemographic Predictors Of Medication Nonadherence Among Latinos Diagnosed With Diabetes Type Ii, Bianca L. Tristan
Walden Dissertations and Doctoral Studies
Latinos of low socioeconomic status are disproportionately affected by diabetes Type II complicated by poor adherence to diabetes Type II medications and management programs. Self-management of diabetes Type II is a tool used to teach health education to patients with diabetes. The objective of this retrospective quantitative study was to explore if there are predictors of nonadherence to diabetes Type II medications and programs among Latinos with diabetes Type II. Data from 200 patient records from a community clinic in Fresno County California were analyzed using both bivariate and multivariate analysis. Selected sociodemographic independent variables were age, gender, income, migrant …
Increasing Knowledge About Alpha-1 Antitrypsin Deficiency In The Chronic Obstructive Pulmonary Disease Population, Maureen Ann Wentink Barta
Increasing Knowledge About Alpha-1 Antitrypsin Deficiency In The Chronic Obstructive Pulmonary Disease Population, Maureen Ann Wentink Barta
Walden Dissertations and Doctoral Studies
The purpose of the project was to increase awareness about alpha-1 antitrypsin deficiency (AATD) in chronic obstructive pulmonary disease (COPD), particularly among those with a familial history of genetic factor AATD; an additional goal was to understand its relationship to COPD. COPD is the third leading cause of death in the United States, with more than half of COPD patients experiencing significant disabilities. Major causes for COPD include smoking, air pollution, secondary smoke, upper respiratory infections, hereditary factors, occupational factors, environmental factors, and socioeconomic factors. Genetic factors, however, also play a significant role in early onset COPD and in those …
Health Literacy And Health Decision Making Attitudes In People With Human Immunodeficiency Virus, Christine Miranda
Health Literacy And Health Decision Making Attitudes In People With Human Immunodeficiency Virus, Christine Miranda
Walden Dissertations and Doctoral Studies
Health literacy has been recognized as a vital issue in the self-care management of persons living with HIV/AIDS (PLWHA). The purpose of this study was to determine the impact of functional, communicative, and critical health literacy dimensions on positive and negative attitudes toward health decision making. The transtheoretical model of health behavior change (TTM) provided the theoretical framework to explain this association. A culturally-adapted survey was used in this cross-sectional study to measure health literacy dimensions, positive and negatives attitudes toward health decision making, and other factors in 100 Puerto Ricans living with HIV/AIDS. Demographic factors and clinical and immunological …
Health-Related Coping Strategies Among Korean Immigrant Women Living In The U.S., Su-Joung Shim
Health-Related Coping Strategies Among Korean Immigrant Women Living In The U.S., Su-Joung Shim
Open Access Theses
Immigrants are known to experience enormous culture transitions that can affect their health. Depressive symptoms are characteristic of immigrants in general, and women immigrants in particular often suffer from mental health problems along with health-related issues. The qualitative study presented here relates the health-related experiences of Korean women immigrants living in a hosting country, the U.S. in this study, with the purpose of exploring their health-related issues and coping strategies.^ Qualitative research methods based on grounded theory were employed to explore the health-related coping strategies of Korean immigrant women in the U.S. A nonprobability, purposive, and snowball sampling method was …
Preliminary Nutritional Profile Analysis Of Box Tops 4 Education Food Products, Hannah Griffith
Preliminary Nutritional Profile Analysis Of Box Tops 4 Education Food Products, Hannah Griffith
Williams Honors College, Honors Research Projects
The marketing of unhealthy food to children is often cited as a cause of the obesity epidemic.1 However, most studies that examine this issue evaluated the marketing of food through print or television advertising. This project investigates the marketing of food products to children through incentive based programs, specifically General Mill’s Box Tops 4 Education. This study undertakes a preliminary systematic analysis of Box Tops food items to determine their healthfulness. A subset of all Box Tops food products was selected for review and a basic quantitative content analysis of priority nutrients was performed. Priority nutrients were identified …
Women's Fitness Week, Claire T. Lucas, Tiffany M. Finch
Women's Fitness Week, Claire T. Lucas, Tiffany M. Finch
Williams Honors College, Honors Research Projects
This project addressed women’s wellness. Many women experience physical and mental health issues related to a lack of physical activity or psychological support. Women’s Fitness Week was offered to women of the University of Akron and the outside community, providing opportunities to learn more about and improve upon the various dimensions of wellness – emotional, environmental, financial, intellectual, occupational, physical, social/cultural, and spiritual. Events were held at the University’s Student Recreation and Wellness Center and encompassed topics such as nutrition, weight training, and self-defense. The goals of this project were to: increase knowledge levels of fitness, health, and wellness, increase …
Novel Interventions For Hiv Self-Management In African American Women: A Systematic Review Of Mhealth Interventions, Kimberly Adams Tufts, Kaprea F. Johnson, Jewel Goodman Shepherd, Juyoung Lee, Muna S. Bait Ajzoon, Lauren B. Mahan, Miyoung Kim
Novel Interventions For Hiv Self-Management In African American Women: A Systematic Review Of Mhealth Interventions, Kimberly Adams Tufts, Kaprea F. Johnson, Jewel Goodman Shepherd, Juyoung Lee, Muna S. Bait Ajzoon, Lauren B. Mahan, Miyoung Kim
Ellmer School of Nursing Faculty Publications
The purpose of this systematic review was to assess the quality of interventions using mobile health (mHealth) technology being developed for and trialed with HIV-infected African American (AA) women. We aimed to assess rigor and to ascertain if these interventions have been expanded to include the broad domain of self-management. After an extensive search using the PRISMA approach and reviewing 450 records (411 published studies and 39 ongoing trials atclinicaltrials.gov), we found little completed research that tested mHealth HIV self-management interventions for AA women. Atclinicaltrials.gov, we found several mHealth HIV intervention studies designed for women in general, forecasting a promising …
Characterization Of Contaminants On Firefighter"S Protective Equipment A Firefighter's Potential Exposure To Heavy Metals During A Structure Fire, Donald F. Gagas
Characterization Of Contaminants On Firefighter"S Protective Equipment A Firefighter's Potential Exposure To Heavy Metals During A Structure Fire, Donald F. Gagas
Online Theses and Dissertations
This research measured heavy metals, specifically cadmium, chromium, copper, and lead, on the surface of the firefighters bunker gear. Despite the fact that many studies have been conducted regarding the presence of organics in smoke emissions from structure fires, very few studies have investigated the extent of heavy metal emissions found during a structure fire. Using a wipe test procedure samples were collected from firefighters following a structure fire and analyzed for metals. Three locations on the bunker gear were used, the knee, elbow, and chest areas. The results showed that varying amounts of cadmium, chromium, copper and lead adhere …
The Current Status Of Safety In High School Chemical Laboratories In Kentucky, Ahmed Rashed Alyammahi
The Current Status Of Safety In High School Chemical Laboratories In Kentucky, Ahmed Rashed Alyammahi
Online Theses and Dissertations
This project is construed as a follow-up of the study conducted by Dr. Jack Gerlovich and his team to assess the status of science safety in Kentucky high schools in 2003-2004. The current study gathered online responses to an expanded survey from 57 high school chemistry teachers in Kentucky. The survey was developed to find answers to four main questions: What is the current status of safety in high school chemical laboratory in Kentucky? To what extent has this status improved or deteriorated since the creation and publication of the Total Science Safety-The Kentucky Edition CD in 2003? What are …
Demographic Profile Of The “Farmworker Population” In The United States, Carlos Siordia, Athena Ramos
Demographic Profile Of The “Farmworker Population” In The United States, Carlos Siordia, Athena Ramos
Reports: Health Promotion, Social & Behavioral Health
The health and economic well-being of farmworkers has been investigated by social scientists for many decades [1,2,3]. General research on occupational safety and farmworker justice has also been developed more recently [4]. Because Hispanics/Latinos are commonly associated with farmworker occupations, especially migrant farm work, research has paid special attention to their population [5]. For example, researchers have investigated the health of Latina farmworkers [6], injury in youth from Latino farmworker families [7], and learning ability amongst Latino farmworkers [8]. However, Latinos only make up about half of the “farmworker population” is the United States (US). The specific aim of this …
Global Response To Local Problems:The Global Health Community Response To The Ebola Outbreak Of 2014, Nicole Thelen
Global Response To Local Problems:The Global Health Community Response To The Ebola Outbreak Of 2014, Nicole Thelen
Undergraduate Theses, Professional Papers, and Capstone Artifacts
Health crises are often met with much support from the global health aid communities, who strive to contain the current health crisis and improve the conditions of the affected society. The recent Ebola outbreak of 2014 is no exception. Driven by public panic and media coverage, the global health community responded in force, dispatching aid organizations, monetary help, and military assistance to both assist those affected with the disease and prevent it from spreading. The World Health Organization, along with Doctors without Borders and many other global organizations, swept in to provide aid to the affected areas. This project examines …
Comparison Between The Asset Ez4 Nco And Impinger Sampling Devices For Aerosol Sampling Of 4,4′-Methylene Diphenyl Diisocyanate In Spray Foam Application, Silvia Puscasu, Simon Aubin, Yves Cloutier, Philippe Sarazin, Huu Van Tra, Sébastien Gagné
Comparison Between The Asset Ez4 Nco And Impinger Sampling Devices For Aerosol Sampling Of 4,4′-Methylene Diphenyl Diisocyanate In Spray Foam Application, Silvia Puscasu, Simon Aubin, Yves Cloutier, Philippe Sarazin, Huu Van Tra, Sébastien Gagné
Études primaires
4,4′-methylene diphenyl diisocyanate (MDI) aerosol exposure evaluation in spray foam insulation application is known to be a challenge. Current available techniques are either not user-friendly or are inaccurate or are not validated for this application. A new sampler has recently been developed to address the user-friendliness issues with other samplers: the ASSET EZ4-NCO, but the use of this sampler in spray foam insulation applications has not been demonstrated or validated. Because of this, the current work was undertaken to provide a comparison of the ASSET sampler with an impinger method, considered to be the best available method in the context …
Determination Of Triglycidyl Isocyanurate From Air Samples By Ultra-Performance Liquid Chromatography Coupled With Coordination Ion Spray Mass Spectrometry, Sébastien Gagné, Marielle Carrier, Simon Aubin
Determination Of Triglycidyl Isocyanurate From Air Samples By Ultra-Performance Liquid Chromatography Coupled With Coordination Ion Spray Mass Spectrometry, Sébastien Gagné, Marielle Carrier, Simon Aubin
Études primaires
Rationale
Ultra-performance liquid chromatography (UPLC) coupled with coordination ion spray tandem mass spectrometry was used for the analysis of air samples containing triglycidyl isocyanurate. The method is not affected by any chromatographic interference and the filter extract is compatible with the UPLC system, as opposed to approaches using high-performance liquid chromatography coupled with ultraviolet detection and gas chromatography coupled with mass spectrometry.
Methods
Accu-cap™ filters that had sampled triglycidyl isocyanurate were extracted using a mixture of acetonitrile/acetone (95/5) diluted with 3 volumes of water and were then analyzed. The mass spectrometry method uses sodium as the alkali adduct complexing …
Parasitology In An Archaeological Context: Analysis Of Medieval Burials In Nivelles, Belgium, S. E. Rácz, Elisa Pucu De Araujo, E. Jensen, C. Mostek, Johnica J. Morrow, M. L. Van Hove, R. Bianucci, D. Willems, F. Heller, Adauto Araujo, Karl Reinhard
Parasitology In An Archaeological Context: Analysis Of Medieval Burials In Nivelles, Belgium, S. E. Rácz, Elisa Pucu De Araujo, E. Jensen, C. Mostek, Johnica J. Morrow, M. L. Van Hove, R. Bianucci, D. Willems, F. Heller, Adauto Araujo, Karl Reinhard
Karl Reinhard Publications
Coprolites were recovered from three burials near the Grand Place of Nivelles, Belgium. These remains yielded evidence of geohelminth parasitism. The evidence contributes to studies of differential parasite egg preservation related to the taphonomic conditions within the three burials. Using coprolite analysis techniques, parasite egg concentrations were quantified for each burial. Coprolites from the individual in Burial 122 were abnormally large and abundant, indicating an intestinal blockage. Additionally, this individual hosted an extremely high number of parasites evinced by the calculated parasite egg concentrations (Trichuris trichiura = 1,577,679 total eggs; Ascaris lumbricoides = 202,350 total eggs). Statistical analyses revealed …
Exploring The Association Between Network, Cognitive, Structural Social Capital And The Risk Of Clinical Depression In Taiwan, Yun-Hsuan Wu
Exploring The Association Between Network, Cognitive, Structural Social Capital And The Risk Of Clinical Depression In Taiwan, Yun-Hsuan Wu
Theses and Dissertations
Depression is the one of most common mental health conditions in Taiwan. Although evidence suggests that social capital is associated with depression, few studies have comprehensively explored the influence of social capital on depression. Also evidence in Taiwan is limited in comparison to other Western countries. Data from the 1997 Taiwan Social Change Survey (n=2,598), which is the only dataset that contains the best available information to measure and compare all three dimensions of social capital (network, cognitive, and structural social capital), were used to examine the association between three dimensions of neighborhood- and individual-level social capital and depression among …
Ethnic Discrimination: Measurement And Associations With Smoking-Related Outcomes Among Arab Male Current And Former Smokers In Israel, Amira Osman
Theses and Dissertations
We evaluated the psychometric properties of two instruments used to assess ethnic discrimination among Arabs in Israel. The “Experiences of Discrimination” (EOD) scale was adapted to assess interpersonal ethnic discrimination (EOD-A) and a new measure was developed to assess perceptions of institutional group discrimination (IGD) against Arabs as an ethnic group. Then, we examined the association between each form of ethnic discrimination (interpersonal and institutional) and smoking outcomes among Arab men from Israel, and whether social support and coping efficacy moderate these associations. Data were analyzed from a cross-sectional study of Arab male current and former smokers, aged 18-64. A …
Statewide Scale-Up Of Group Prenatal Care In South Carolina, Kristin M. Van De Griend
Statewide Scale-Up Of Group Prenatal Care In South Carolina, Kristin M. Van De Griend
Theses and Dissertations
Background: Poor birth outcomes and racial disparities in birth outcomes in South Carolina are widely recognized problems. To improve maternal and child health outcomes, especially among vulnerable groups, universal access to timely, appropriate, and effective care should remain a priority through increased availability and accessibility. An interagency collaborative in South Carolina expanded CenteringPregnancy (CP) from two to five medical practices throughout the state. CenteringPregnancy is associated with improved birth outcomes and reduced rates of racial disparities in preterm birth throughout the United States. Important questions in the literature remain about strategies and determinants of scaling up sexual and reproductive …
Cluster Analysis With Batch Effect, Yifan Tang
Cluster Analysis With Batch Effect, Yifan Tang
Theses and Dissertations
Clustering, as a fundamental process in data science, is frequently used in preliminary data analysis. Batch effects are a powerful source of variation that can come from many sources in data collection, and influence data. We propose a method to simultaneously remove batch effects and perform cluster analysis. We see a batch effect as a fixed value added on to each batch, and do not make assumptions about the distribution of batch effects. We represent the data using a Gaussian mixture model, and use the EM algorithm to estimate the cluster means, the cluster covariance matrices, and the batch effects, …
The Influence Of Self-Reported Degree Of Masculinity/Femininity On Condom Use Among Black Men Who Have Sex With Men In The Deep South, Elizabeth D. Peeler
The Influence Of Self-Reported Degree Of Masculinity/Femininity On Condom Use Among Black Men Who Have Sex With Men In The Deep South, Elizabeth D. Peeler
Theses and Dissertations
In the United States, 50,000 Americans are diagnosed with HIV each year (CDCa, 2014). The HIV/AIDS epidemic has had a particularly devastating impact on the southern U.S., especially the Deep South – Alabama, Georgia, Louisiana, Mississippi, North Carolina, and South Carolina (Reif, Whetten, Wilson, McAllaster, Pence, Legrand, & Gong, 2014). The Deep South, while only composing of 36% of the national population, accounts for 50% of all people living with HIV/AIDS in the nation (Human Rights Watch, 2010). No other population has been hit harder than men who have sex with men (MSM; Prejean, Tang, & hall, 2013). Black MSM …
Impact Of E-Cigarettes On Physician Recommendations Of Tobacco Use Cessation Pharmacotherapy, Omar El Shahawy
Impact Of E-Cigarettes On Physician Recommendations Of Tobacco Use Cessation Pharmacotherapy, Omar El Shahawy
Theses and Dissertations
Introduction: E-cigarettes have been marketed as smoking cessation aids and harm reduction strategies. Prior regional surveys found that physicians are recommending them to patients despite the lack of evidence supporting these industry claims. Yet, little is known about physicians’ beliefs regarding e-cigarettes and whether these beliefs are associated with them recommending e-cigarette use in clinical practice. Methods: This three-manuscript dissertation used a mixed-methods approach including both qualitative and quantitative research methods. The aims were to: (1) Uncover the factors associated with primary care physicians’ (PCPs) decisions to recommend e-cigarettes to their patients for tobacco use cessation; (2) Estimate the prevalence …
Factors That Influence Breast Cancer Diagnoses In Virginia Women 40-64 Years Old Who Utlized The Every Woman’S Life Program 1998-2012, Melanie C. Dempsey
Factors That Influence Breast Cancer Diagnoses In Virginia Women 40-64 Years Old Who Utlized The Every Woman’S Life Program 1998-2012, Melanie C. Dempsey
Theses and Dissertations
This dissertation examines sociodemographic determinants and preventive health behaviors among women 40-64 years of age who participated in the Virginia Department of Health’s Every Woman’s Life breast cancer screening program. Utilizing secondary data, this research sought to explore patterns of breast cancer incidence, mammography screening utilization and sources of health information among low-income women.
The Virginia Department of Health provided a large sample size (N=34,942) on which to perform binary logistic regression analyses. Sociodemographic determinants and preventive health behaviors were analyzed as potential influencing factors in the diagnosis of breast cancer, the stage at the time of diagnosis and source …
Provider Recommendations For Human Papillomavirus Vaccine (Hpv) Among Adolescent Males In Southwest Georgia Counties And The Associated Hpv Prevalence In This Population, Benjamin K. Poku
College of Graduate Studies: Theses & Dissertations
Objective: The purpose of this research study was to examine the variation in healthcare providers’ behavior in recommending the Human Papillomavirus (HPV) vaccine to young male adolescents (aged 11-12), middle male adolescents (aged 13-17) and late male adolescents (aged 18-26) in rural Southwest Georgia counties. This research also aimed to identify factors associated with providers’ behaviors concerning HPV vaccination recommendation to youth in various age groups.
Methods: Upon IRB approval, secondary data were obtained from Albany Area Primary Care for a paper-based survey that was conducted in 2014 using a representative random sample of family physicians (n=12), pediatricians (n=6), and …
Examination Of Racial/Ethnic Disparities In Ovarian Cancer Stage Of Diagnosis, Surgery Treatment And Survival: Multilevel Analysis Of 2001-2012 Seer Data, Chen Chen
College of Graduate Studies: Theses & Dissertations
Context. Racial/ethnic disparities in cancer outcomes are major public health concerns. Ovarian cancer is the tenth most common cancer and the fifth leading cause of cancer-related deaths among women. Identifying individual- and contextual-level factors contributing to racial/ethnic disparities in ovarian cancer stage of diagnosis, surgery treatment and survival is necessary for reducing and eliminating these disparities.
Objective. The study aims to examine racial/ethnic disparities in ovarian cancer diagnosis, surgery treatment and survival outcomes; to explore individual- and contextual-level factors contributing to these disparities, and to examine the trend of ovarian cancer racial/ethnic disparities from 2001 to 2012.
Methods. The …
Public Health Implications Associated With The Practice Of Utilizing Tires To Singe Meat In Three Major Cities Of Ghana: A Concurrent Mixed Methods Study, Tempest D. Hill
Public Health Implications Associated With The Practice Of Utilizing Tires To Singe Meat In Three Major Cities Of Ghana: A Concurrent Mixed Methods Study, Tempest D. Hill
College of Graduate Studies: Theses & Dissertations
Utilization of automobile tires to singe meat (e.g., cows) intended for human consumption presents public health risks due to hazardous chemicals released into the environment and meat. This has become a common practice in some African countries such as Ghana. The objective of this study was to investigate the awareness and perception of the residents in three major cities of Ghana (Cape Coast, Kumasi and Accra) using the Health Belief Model and Social Ecological Model. Survey participants (n=196) and focus group discussion members (n=37) completed the study. Data collected from study participants included meat consumption, awareness of the use of …
A Decision Support Simulation Model For Bed Management In Healthcare, Raja A. Baru
A Decision Support Simulation Model For Bed Management In Healthcare, Raja A. Baru
Masters Theses
"In order to provide access to care in a timely manner, it is necessary to effectively manage the allocation of limited resources such as beds. Bed management is key to the effective delivery of high-quality and low-cost healthcare. An efficient utilization of beds requires a detailed understanding of the hospital's operational behavior. It is necessary to understand the behavior of a hospital in order to make necessary adjustments to its resources, and policies, which can improve patient's access to care. The aim of this research was to develop a discrete event simulation to assist in planning and staff scheduling decisions. …
She Got Her Period: Men's Knowledge And Perspectives On Menstruation, Ishwari Rajak
She Got Her Period: Men's Knowledge And Perspectives On Menstruation, Ishwari Rajak
All Graduate Theses, Dissertations, and Other Capstone Projects
Research show that men and women often do not converse freely about menstruation. Shame, taboos and myths associated with menstruation silence the conversation. Silencing conversations about menstruation have negative consequences on women, including: objectification of women's bodies, stereotyping of women as physically, morally and emotionally inferior to men and to extreme cases women losing their uterus due to unhygienic means of menstrual management. On the one hand, not addressing menstruation openly has devastating consequences on women but on the other hand, most men seem oblivious about the impacts on women. Therefore, it is important to engage in open dialogues about …
Statistical Methodology To Improve The Understanding Of Dna Methylation Data, Lindsay Leigh Waite Jones
Statistical Methodology To Improve The Understanding Of Dna Methylation Data, Lindsay Leigh Waite Jones
All ETDs from UAB
The study of epigenetics involves the investigation of genomic elements that do not directly affect DNA sequence but are stable and preserved during cell division. One of the most commonly studied epigenetic elements is DNA methylation, which occurs when a methyl group is added to a cytosine residue in the DNA sequence. The advancement of technology to quantify DNA methylation, including bisulfite sequencing and bisulfite microarrays, has led to a large amount of available data. However, many questions still remain as to how to statistically analyze this data. This dissertation addresses some statistical concerns related to the analysis of DNA …