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Prolonging Oxygen Consumption During Preservation Of Canine Kidneys By The Addition Of Continuous Dialysis, Daniel Dall'olmo, Stanley G. Dienst

Henry Ford Hospital Medical Journal

Kidneys were preserved by continuous pulsatile perfusion and their metabolic rate monitored by O2 consumption. Experiments were carried out to determine if dialyzing the perfusate to supply metabolic substrates would aid in kidney preservation. A control group was compared against two experimental groups at 25°C. Average preservation time before fall off of oxygen consumption differed for each group: control - 8 hours, dialysis with amino acids - 6 hours, dialysis with amino acids and cofactors - 11 hours. Results indicated that, if suitable concentrations of metabolic substrates and cofactors were used, the preserved kidneys maintained higher levels of O2 consumption …

Oral Contraceptives And Myocardial Infarction: Report Of Three Cases And Review Of The Literature, Mohsin Alam, Remigio Garcia, Ellet H. Drake

Henry Ford Hospital Medical Journal

Three cases are presented of young women who had myocardial infarctions possibly due to coronary thrombosis related to oral contraceptive therapy. These patients had none or very few risk factors for coronary artery disease. In two of the patients, selective coronary arteriograms showed normal results on the third and tenth week after the diagnosis was established. The pathogenesis of coronary artery thrombosis in patients receiving oral contraceptives containing estrogen is still controversial, but it appears to be the result of its multifactorial effect on the platelets, coagulation factors, vessel wall, blood pressure, postprandial blood sugar and abnormalities of lipid metabolism.

A Screening, Referral, And Follow-Up Program For High Blood Pressure At Henry Ford Hospital: Part Ii. Results Of Referral And Follow-Up, John C. Erfurt, Andrea Foote, John R. Caldwell

Henry Ford Hospital Medical Journal

This is the second of two articles on the Henry Ford Hospital screening, referral, and follow-up program for high blood pressure. The first reported on the screening results of the program, along with associated epidemiological findings. This article presents the results of referral and follow-up. During the period of March 27 through December 11, 1975, 808 people were screened; 196 (24%) were found to have uncontrolled high blood pressure and were referred to physicians for diagnosis and possible treatment for hypertension. The program is currently following up with these people and their physicians to insure successful referral and maintenance of …

Penetrating Abdominal Trauma: A Morbidity And Mortality Report Of A Growing Social Problem, F. Samhouri, C. Grodsinsky, T. A. Fox Jr.

Henry Ford Hospital Medical Journal

The management of penetrating abdominal wounds has become a necessity in most larger metropolitan hospitals. Most of these wounds are produced by low velocity gunshots, but some are stab wounds. Several recent advances have contributed to the more successful management of penetrating abdominal wounds. These include: 1) improvement in on-site care by various emergency medical services, 2) more rapid transportation of the injured to a facility equipped to care for such patients, 3) vigorous resuscitative and diagnostic measures, 4) prompt and adequate surgical intervention, 5) improvements in anesthesia techniques, and 6) improvements in blood banks. From 1969 to 1974, 843 …

Use Of The Weibull Distribution For Analysis Of A Clinical Therapeutic Study In Rheumatoid Arthritis, W. R. Mccrum, J. T. Sharp, G. B. Bluhm

Henry Ford Hospital Medical Journal

This paper introduces the use of the Weibull distribution function for the analysis of small samples of clinical data. It is compared with the use of the conventional analysis of variance in determining the results of a study comparing the use of gold salts and a placebo in the treatment of rheumatoid arthritis. Although the samples were small, 14 control patients and 13 who were treated, analysis of variance determined several significant differences between the two groups. The use of the Weibull distribution, however, not only confirmed these differences, but also determined several more differences between the two groups that …

Publications Of The Staff Of The Henry Ford Hospital And The Edsel B. Ford Institute For Medical Research

Henry Ford Hospital Medical Journal

No abstract provided.

A Study In Self-Defeat: The Public Health Venereal Disease Clinic, Joseph F. Sheley

The Journal of Sociology & Social Welfare

This paper relates the results of three months of participant observation and interviews in a public venereal disease clinic. The research was directed toward assessment of the relationship of clinic efficiency (a smoothly operating bureaucratic clinic) and clinic effectiveness (a major reduction of illness within a community). The venereal disease clinic is described as an efficient and well planned health unit with three major objectives: a) checking the increase of V.D. through preventive medicine; b) detection and treatment of V.D. within the community; and c) provision of health services to lower S.E.S. segments of the population. Research results indicate that …

Sideroblastic Anemias, Louis D. Saravolatz

Henry Ford Hospital Medical Journal

Sideroblastic anemias are reviewed with emphasis on clinical features, biochemical studies, treatment modalities and prognosis. A classification of these anemias based on etiology is also provided.

A Screening, Referral, And Follow-Up Program For High Blood Pressure At Henry Ford Hospital: Part I. Results Of Screening, Andrea Foote, John C. Erfurt, John R. Caldwell

Henry Ford Hospital Medical Journal

Data are reported on the screening results from the Henry Ford Hospital screening, referral and follow-up program for high blood pressure. The report covers the period of March 27 through December 11, 1975, during which time 808 people were screened in the hospital lobby. Thirty-nine percent were found upon initial screening to have high blood pressure readings or previously diagnosed hypertension. Of these people, 70% were already under treatment for hypertension, but only 21% showed adequate blood pressure control (with readings below 140/90 mm Hg). Those with high readings were referred to their physicians. A paper on the results of …

Susceptibility Of Clinical Isolates Of Bacteria To Cefamandole, Cefoxitin And Cephalothin, R. Del Busto, A. Suarez, E. Quinn, D. Pohlod

Henry Ford Hospital Medical Journal

The in vitro susceptibility was determined of 274 isolates to cephalothin and two new antibiotics, cefamandole and cefoxitin. Cefamandole was comparable to cephalothin in preventing growth of cultures of the gram positive organisms except for penicillin-resistant Staphylococcus aureus which was more sensitive to cephalothin. Cefamandole was more active than cephalothin against all the gram negative bacteria including Haemophilus influenzae and in addition it was active against many strains of Enterobacter sp. Cefoxitin was less active than cephalothin against the gram positive organisms but it was more active against most of the gram negative bacteria. In addition. It was active against …

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

The Association Of Acute Cerebellar Encephalopathy And Neuroblastoma, M. Reza Jahadi, John G. Whitcomb, Ratnaker Kini, Robert H. High

Henry Ford Hospital Medical Journal

Acute cerebellar encephalopathy is a rare neurological disorder associated with neuroblastoma and is characterized by ataxia, somatic myoclonus and opsoclonus. The pathogenesis which underlies the relationship between the two conditions is obscure. One patient with neuroblastoma and acute cerebellar encephalopathy Is reported. The occurrence of neuroblastoma and acute cerebellar encephalopathy In this case may be coincidental but, on the basis of frequent recent reports of this association, a possible relationship between these two entities is entertained. It is therefore recommended that all patients with acute cerebellar encephalopathy be surveyed for unapparent neuroblastoma. The search should include chest and skeletal X-rays, …

Immunological Aspects Of Neoplastic Diseases, V. Radhakrishna

Henry Ford Hospital Medical Journal

The immunological approach to neoplastic disease is gaining favor because malignant tumors are associated with immunodeficient states. Mesenchymal tumors have been seen in renal allograft recipients. The discovery of carcinoembryonic antigen, alfafetoprotein and other protein antigens associated with malignant diseases are other factors. Spontaneous regression of malignant neoplasm has been attributed to an effective immunologic process in the host. Identification of tumor specific antigens may explain these spontaneous tumor regressions. It may not be too optimistic to expect tumor vaccine of some sort within the next few years. B.C.G. and other nonspecific immunostimulants are under investigation for treatment of malignant …

Productivity Of The Roll-Streak Method To Perform Anaerobic Bacteriology In The Routine Clinical Laboratory, Thomas R. Neblett

Henry Ford Hospital Medical Journal

Data presented are derived from one year of performing routine clinical anaerobic bacteriology by the roll-streak tube method. 826 specimens from 1508 (54.8%) contained anaerobes. 162 specimens were polymicrobic (19.6%) and contained 528 strains of a total of 1051 isolated (50.2 %). 479 blood specimens contained 525 strains of anaerobes. Propionibacterium, considered a contaminant, occurred 209/210 times in blood as the sole isolate. Bacteroides occurred alone or polymicrobically 308 times and comprised 54.7% of the blood isolates and 32.5% of the total anaerobic genera isolated. Clostridium, Peptococcus and Fusobacterium were the next most frequently occurring anaerobes. The roll-streak method is …

Publications Of The Staff Of The Henry Ford Hospital And The Edsel B. Ford Institute For Medical Research

Henry Ford Hospital Medical Journal

No abstract provided.

Clarke M. Mccoll M.D. In Memoriam 1898-1976, Dwight C. Ensign

Henry Ford Hospital Medical Journal

No abstract provided.

Commencement Program 1976, Loma Linda University

Commencement Programs

CONTENTS

2 | 1976 Events of Commencement

3 | Conferring of Degrees

7 | Candidates for Degrees

25 | Awards

27 | Academic Costume

An Examination Of The Relationship Between Population Density, Density Related Social Factors, And Physical Morbidities, Douglas King Huebner

Dissertations and Theses

The relationship between the number of persons per room in the home and the relative occurrence of stress-related morbidities of hospitalized patients is investigated. The social factors of age, social class, and level of social support also are examined as they relate to both density and morbidity type occurrence. The population under study is composed of all Kaiser-Permanente Medical Care Program members twenty years of age and older, discharged from Bess Kaiser Hospital during 1974, and whose diagnosed morbidity was included in specific morbidity categories. All data were obtained through the facilities of the Health Services Research Center, Kaiser Foundation …

Consumer Satisfaction With Services In A Mental Health Center, Sandra M. Hare

Loma Linda University Electronic Theses, Dissertations & Projects

An exploratory study was done with descriptive comparative components to examine the levels of consumer satisfaction at a mental health center, and there was also the intent to determine if satisfaction or dissatisfaction in one area of service affected the general satisfaction level. In addition, other variables and demographic data included in the questionnaire were examined.

Data collection was done by the use of a 23-item questionnaire that was administered to three departments of service, Outpatient, Drug Abuse, and Day-care, at North Orange County Mental Health Services. The sample group consisted of any adult in treatment who had made three …

Surgical Techniques For Arthrodesis Of Two To Four Adjacent Spinal Vertebrae Throughout The Entire Spinal Column, Kent K. Wu

Henry Ford Hospital Medical Journal

Surgical techniques for cervical, thoracic and lumbar spinal fusions have been described. So far, 51 such fusions have been performed with satisfactory results.

Publications Of The Staff Of The Henry Ford Hospital And The Edsel B. Ford Institute For Medical Research

Henry Ford Hospital Medical Journal

No abstract provided.

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Cushing's Disease: Spontaneous Remission Following Severe Headache, Raymond C. Mellinger

Henry Ford Hospital Medical Journal

A young woman was found to have persistent Cushing's syndrome one year after surgical removal of both hyperplastic adrenal glands. Improvement followed pituitary irradiation butshe developed skin pigmentation. Remission of the adrenal hyperfunction occurred only after several months of therapy with o,p'-DDD. Within 15 months, the recurrent disorder required a second course of DDD with resulting adrenal insufficiency. Eighteen months later, however, steroid supplements were no longer required and increasing Cortisol levels indicated still another imminent relapse. There was no enlargement of the sella turcica. The patient had received no treatment whatever for nearly nine months when she experienced a …

Endoscopic Retrograde Pancreatic Duct Cannulation (Erpc): An Aid To Pancreatic Surgery, C. Grodsinsky, B. Schuman, B. E. Brush

Henry Ford Hospital Medical Journal

Retrograde endoscopic pancreatic duct cannulation for evaluation of patients with chronic pancreatitis is reviewed over the last two years. Of 40 patients that were endoscoped, 30 had a successful pancreatogram. The X-ray findings fell into three groups: 1) single and multiple stenosis, 2) diffuse narrowing, and 3) apparently normal duct. This procedure proved of value in ruling out or delaying surgical operation in 10 persons. Twenty-one patients underwent operations. Thirteen had a 95% pancreatectomy, one had drainage of a necrotic collection thought to be a pseudocyst and one had a pseudocyst resected. One had a gastrojejunostomy and vagotomy bypassing a …

Infections Due To Trichosporon Cutaneum, An Uncommon Systemic Pathogen, Tom Madhavan, John Eisses, Edward L. Quinn

Henry Ford Hospital Medical Journal

Multiple isolations of T. Cutaneum from the blood stream of two patients enabled the authors to characterize the morphology, biochemical reactions and antibiotic susceptibility of T. Cutaneum. This organism appears to be an opportunistic pathogen and responds promptly to intravenous Amphotericin B or oral 5-Fluorocytosine.

Bupivacaine As A Local Anesthetic For Hernia Repair, Joseph L. Ponka, James A. Sapala

Henry Ford Hospital Medical Journal

Bupivacaine hydrochloride is a safe, useful local anesthetic agent for repair of groin hernias. Prolonged anesthesia, lasting six hours or longer, was observed In 94 of WO patients. No toxic effects involving the central nervous system were observed using a 0.25% solution with epinephrine. Hypotension and cardiac arrhythmia occurred in one patient. Wound complications, such as hematomas and ecchymosis, were more common with Bupivacaine than when Chlorprocaine was used. However, painstaking hemostasis, which required ligation of even the tiniest blood vessels, reduced the wound complications. As experience is gained in the use of Bupivacaine, complications will be reduced to a …

Some Of The Effects Of Domestic Sewage Discharged Into Hickman And Jessamine Creeks In Jessamine County, Kentucky, Henry H. Howell, Mike W. Jones, Robert A. Kuehne

KWRRI Research Reports

A 6-week study was made in the summer of 1971 as an initial effort to determine the extent of pollution that the three sewage disposal plants in Jessamine County, Kentucky, are contributing to its streams. With the rapid population increase in Lexington and nearby municipalities, this study should furnish a basis of comparison for future investigations. Eighteen collecting stations were established in riffle areas of Hickman and Jessamine Creeks, and coliform bacteria, macro-invertebrate populations, fish populations and chemical water quality of each riffle area were studied.

Hickman Creek's flow was augmented by approximately 3,100,000 gallons/day (11,735 -m³/day) from …

Comparative Analysis Of Hospital Utilization In Urban And Rural Counties, James R. Dingels

Journal of the Minnesota Academy of Science

Hospital utilization, when measured as patient days per population, exhibited generally insignificant relationships with factors concerning population characteristics, hospital resources, financial assistance, and degree of urbanization. Adjusted multivariate linear regression results indicated that number of physicians per population did possess significant effects, while other independent variables remained significant. Additional research, as well as refinement of present data, appear paramount to further validation procedures.

Lymphangiography In Staging Carcinoma Of The Prostate. A Comparison With Operative Findings, Joseph C. Cerny, Malcolm Weckstein, Riad Farah

Henry Ford Hospital Medical Journal

Pedal lymphangiography was performed In 30 patients who subsequently underwent radical retropubic prostatectomy, and radical pelvic lymphadenectomy. In 24 of 30 patients, lymphangiograms correctly predicted the presence or absence of nodal Involvement. In spite of certain limitations of the technique. It is considered an essential diagnostic study in patients considered for possible radical prostatic surgery, or in patients who may be candidates for external megavoltage radiotherapy to the prostate gland and its lymphatic drainage.

Palliative Urinary Diversion In Adenocarcinoma Of The Prostate, R. C. Youngman, Joseph C. Cerny

Henry Ford Hospital Medical Journal

Ten patients with inoperable prostatic carcinoma, producing ureteral obstruction and azotemia, underwent palliative urinary diversion. Good quality survivals of two months to three years were obtained. These results compare favorably with the good results seer) In gynecologic neoplasm of the bladder, colon and breast. In selected cases of carcinoma of the prostate, palliative urinary diversion is indicated when the prospects exist for further benefit from chemotherapy or radiotherapy.