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Hyperthermic Perfusion 16 Years After Its First Clinical Applications, R. Cavaliere, G. Moricca, F. Di Filippo, L. Aloe, G. Monticelli, F. S. Sartori

Henry Ford Hospital Medical Journal

It is known that above-normal temperatures (42°-42.5°C) provoke selective damage to neoplastic cells. We used heated circulating blood as a method for heat transfer on patients with limb tumors. From October 1964 to December 1979, we treated a total of 198 patients with hyperthermic perfusion for melanoma of the limbs (91), osteosarcoma (57), and soft tissue sarcoma (50). For melanoma patients, the five-year survival rate, excluding Stage IV, was 60%. For patients with soft tissue sarcoma, the five-year survival rates were 53% and 56% for hyperthermic perfusion and hyperthermic antiblastic perfusion. respectively. For 29 patients with osteosarcoma, hyperthermic perfusion was …

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Local Microwave Hyperthermia In Cancer Therapy: Preliminary Report, Carlos A. Perez, Walter Kopecky, Robert Baglan, D. Venkata Rao, Richard Johnson

Henry Ford Hospital Medical Journal

This report summarizes our preliminary experience at the Mallinckrodt Institute of Radiology treating 26 patients with metastatic tumors with hyperthermia and irradiation. Patients received 400 rad fractions given every 72 hours (twice weekly) for a total of 2400, 2800, 3200, or 4000 rad followed by hyperthermia. In addition, 18 lesions were treated according to a protocol designed by the Radiation Therapy Oncology Group (RTOG) for superficial measurable tumors to receive three doses of 500 rad followed by hyperthermia (six lesions) or irradiation alone (three doses of 600, 700, or 800 rad) every 72 hours. Hyperthermia was administered with 2450 MHz …

Microwave Hyperthermia At 2450 And 915 Megahertz Frequencies, Kenneth H. Luk

Henry Ford Hospital Medical Journal

Microwave hyperthermia at frequencies of 2450 and 915 megahertz (MHz) was used to treat superficial measurable tumors of different histopathologies at various sites. Forty-seven patients received 59 courses of treatment; they were able to tolerate temperatures up to 42.5X1. Although hyperthermia alone (40°-42.5°C) did not produce an effective response, hyperthermia and radiation together (up to 2700 rad in nine fractions over three weeks) produced complete and partial responses in three-fourths of the treatment courses. The combination of hyperthermia and chemotherapy may have great potential, but confirmation of these clinical impressions will depend on a much larger series of patient data. …

Hyperthermia Treatment Of Experimental Tumors, J. Denekamp, S. A. Hill, F. A. Stewart

Henry Ford Hospital Medical Journal

The therapeutic advantage of combining hyperthermia with x-irradiation to treat tumors depends on whether or not it is possible to achieve greater thermal sensitization of tumors than of normal tissues. To determine such therapeutic gain factors (TGE), we assessed the response of mouse skin and seven transplantable mouse tumors to graded x-ray doses given alone or combined with moderate heat (42.5°C for 60 minutes). We constructed dose response curves for the average early skin reaction and for the induced delay in tumor regrowth to an arbitrarily chosen size. We studied the following areas: 1) the therapeutic gain of combining heat …

Namru-3 Translations Of Parasite Literature From Russian, French, Japanese, Etc. Into English (1921-1981) T1401-T1500, United States Naval Medical Research Unit Number Three, Cairo, Medical Zoology Department

United States Naval Medical Research Unit 3: Publications

T1401. TRANSLATION FROM RUSSIAN. L'VOV, D. K., GROMASHEVSKY, V. L., SIDOROVA, G. A., TSIRKIN, Yu. M. CHERVONSKY, V. L. GOSTINSHCHIKOVA, G. V. and ARISTOVA, V. A. (1971). Isolation of a new arbovirus Baku of Kemerovo group from argasid ticks Ornithodoros coniceps. in Azerbaijan. Vop. Virus., 16(4):434-437.

T1402. TRANSLATION FROM RUSSIAN. ALEKSANDROV, Yu. V., KORYAGIN, V. L. and YOVAL'CHUK, Zh. T. (1970). Observations on ecological biological properties of Hyalomma plumbeum ticks in eastern Crimea. Tezisy Dokl. 2. Akarol. Soveshch., (1):22-24.

T1403. TRANSLATION FROM RUSSIAN. MATEVOSYAN, K. Sh., KARASEVA, P. S. and SEMENOV, B. F. (1974). Study of potential arbovirus foci in …

Commencement Program 1981, Loma Linda University

Commencement Programs

CONTENTS

3 | The President's Greeting

4 | 1981 Events of Commencement

5 | The Academic Procession

6 | The Speakers

9 | The Honorees

11 | Order of Programs

• School of Medicine, 12
• Graduate School, 18
• School of Nursing, 22
• School of Dentistry, 25
• School of Education, 31
• College of Arts and Science, 36
• School of Allied Health Professions, 41
• School of Health, 47

Job Satisfaction Of Home Care Case Managers: An Evaluative Look At One Home Care Corporation, Scott A. Bass, Richard Rowland

Gerontology Faculty Publication Series

Senior Home Care Services — Boston III, Inc. is a six year old private non-profit corporation with an annual budget of nearly $5 million. The agency currently delivers services to approximately 2,500 functionally impaired senior citizens per month in the Boston neighborhoods of South Boston, East Dorchester/Mattapan, East Boston, Beacon Hill, West End, North End, Charlestown, and South Cove. Over 5 7% of the case management staff has worked at the agency less than one year and 92.9% of the case management staff has worked at SHC for less than two years. The high turnover rate is well known to …

Women And Handicrafts: Myth And Reality, Jasleen Dhamija

Poverty, Gender, and Youth

This issue of SEEDS reviews handicrafts as a means of providing income to women. In some instances, crafts are a solid source of income and can also provide women with a link to their own cultural heritage. In most instances, however, crafts production concentrates women in an area that is labor intensive and exploitative, providing a meager income for long hours of work. Handicrafts can be a means of increasing income for women in some settings, but only under the conditions outlined in this report, since crafts are specialized activities which have limited markets and offer limited potential as a …

Your Child's Teeth (1981), American Dental Association, Bureau Of Health Education And Audiovisual Services, American Society Of Dentistry For Children

Patient Dental Health Education Materials 1929-1981

No abstract provided.

Health Problems Of Selected Lds Missionaries Throughout The World, Susan Jensen

Theses and Dissertations

The purpose of this study on Mormon missionaries was to determine the effect of health on missionary activity time, age, sex, months in field, laboring city population, monthly mission cost, living conditions, diet, pre-existing conditions, adequacy of medical care, nativity, effectiveness, emotional health, interpersonal relationships, and motivation and enthusiasm. In addition the research attempted to ascertain the effect of the selected independent factors on ill missionary lost time.

As an outcome of the statistical analysis performed on this study's sample the following results were obtained. Respiratory disorders, gastrointestinal difficulties and orthopedic injuries were the most common health problems. Well missionaries …

Habitat, The New United Nations Initiative In Human Settlements, Norman Miller, James F. Hornig

Dartmouth Scholarship

Habitat, the synonym for the United Nations Center for Human Settlements, is a new UN agency with a staggering mandate. Its charge is to assist developing nations in settlement policy and planning, in slum upgrading, urban renewal, and in the development of shelter materials. The upgrading of infrastructural services, such as those involving finance, loans, building codes, and regulatory laws, are a part of the mandate, as are such basic elements as clean water, electricity, and sewage removal. Still further, the agency, which is headquartered in Nairobi, Kenya, is charged with helping generate rational land-use policies, gaining public participation, and …

A Study Of Nata Certification Candidates' Perception Of Preparation Before And After Taking The Certification Exam, Richard J. Lloyd

Masters Theses

No abstract provided.

Lomax Norms For Eastern Illinois University Women Athletes On The Twelve Minute Run, Linda J. Lomax

Masters Theses

No abstract provided.

Physical Education Program For Autistic Children, Karen Sue Moss Smith

Masters Theses

No abstract provided.

Anywhere But Here: An Introduction To State Control Of Hazardous-Waste Facility Location, A. Dan Tarlock

Articles by Maurer Faculty

No abstract provided.

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Henry Ford Hospital Clinicopathological Conference: Hypercoagulable State In Cancer Of The Pancreas In A 57-Year-Old Man

Henry Ford Hospital Medical Journal

No abstract provided.

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Phleborheography: A Correlative Study With Venography, Joseph P. Elliott Jr., John H. Hageman, Ann C. Belanger, Roger F. Smith

Henry Ford Hospital Medical Journal

The Vascular Laboratory of Henry Ford Hospital has used the Cranley-Grass Phleborheograph (PRG) as the primary noninvasive method to determine the presence or absence of deep venous thrombosis (DVT) in the lower limbs since December 1977. In order to determine its proper role and clinical reliability, we compared the diagnostic accuracy of phleborheography with contrast venography. From December 1977 through December 1978, 483 cases (963 limbs) were successfully examined by PRG. Ofthese, 111 cases (216 limbs) also had contrast venography. The PRG was confirmed as normal in 151 out of 157 (6 false negatives). There were 53 abnormal PRCs, with …

Glucose Phosphate Isomerase Deficiency: Unusual Acute Hemolytic Crisis In A Middle-Aged Woman, Koichi Maeda, Sheikh M. Saeed, Raymond W. Monto, Ernest Beutler

Henry Ford Hospital Medical Journal

Hereditary hemolytic anemia associated with glucose phosphate isomerase (GPI) deficiency was first reported in 1967. Since then, about 30 cases have been reported in the literature; their ages ranged between 1 and 26 years. We present a case of glucose phosphate isomerase deficiency in a 56-year-old woman. Steroid therapy seemed to resolve our patient's acute stage. Since it has not been mentioned previously, further evaluation is necessary. Consideration of this deficiency may be helpful in investigating hemolytic anemia, regardless of the patient's age.

Intensity Of The Second Heart Sound: Relation Of Physical, Physiological And Anatomic Factors To Auscultatory Evaluation, Paul D. Stein, Hani Sabbah

Henry Ford Hospital Medical Journal

The intensity of the heart sound depends upon: 1) the distensibility of the aortic and pulmonary valves; 2) hemodynamic factors that cause the valves to distend and vibrate; 3) viscosity of the blood and its ability to inhibit diastolic valve motion; 4) the configuration of the aorta, pulmonary artery, and ventricle and the ability of the walls of the great vessels and ventricles to absorb or reflect sound energy; and 5) the capability of sound to be transmitted to the chest wall. Recognizing how these physical, physiological, and anatomic factors interact can help us to interpret auscultation of the intensity …

A Selective Approach To Bleeding Esophageal Varices, Glyn G. Jamieson, Irwin B. Faris, John Ludbrook

Henry Ford Hospital Medical Journal

It is possible that the best results of treatment for bleeding esophageal varices will come when a selective approach is used. In patients bleeding acutely and in patients with poor liver function shunt operations should be avoided, and a direct attack on the varices with either sclerosant therapy, percutaneous obliteration, or staple gun gastro-esophageal transsection should be carried out. In patients who have stopped bleeding, or those in whom elective treatment is being undertaken, the best operation at present appears to be selective distal splenorenal shunt.

Letters To The Editor

Henry Ford Hospital Medical Journal

No abstract provided.

Effects Of Analgesia On The Newborn, Linda Roe

Masters Theses & Specialist Projects

Obstetric analgesia and anesthesia is an important concern today. The purpose of this study was to evaluate the effects of analgesia used in labor and delivery on the mother and newborn. The information obtained in this study evaluated the amount, time and types of analgesia and the effects on the mother and the newborn.

Previous research has indicated adverse effects of analgesia and anesthesia on both mother and newborn, but conclusive results have not been obtained. Depressed respiratory function, increased use of oxygen, and low Apgar scores are among the effects reported for the newborn. Decreased uterine function, decreased satisfaction …

Commencement Program 1980 (Summer Conferring Of Degrees), Loma Linda University

Commencement Programs

CONTENTS

3 | The Academic Procession

4 | Conferring of Degrees

8 | Candidates for Degrees

15 | Awards

Evaluation Of The Impact Of A Health Education Program On The Rate Of Recurrent Urinary Tract Infections In A Selected Female Outpatient Population, Lo Lumsden

Community & Environmental Health Theses & Dissertations

The present study attempted to assess the impact of a health education program focused on those preventive measures or avoidance behaviors an individual could incorporate. into daily living to reduce the incidence of urinary tract . infections. An experimental group, consisting of seventeen volunteers was exposed to a health. education program, and then compared to a seventeen member control group. A statistically significant reduction in the incidence of cystitis, occurred within the experimental group after health education intervention. The results were not statistically significant when the experimental post-test was compared with the control post-test.

The Effects Of Family Counseling On The Treatment Of Juvenile Status Offenders Of The Norfolk Juvenile And Domestic Relations Court, Valerie Karen Freeman

Community & Environmental Health Theses & Dissertations

The present study was conducted as a service to ~e Norfolk Juvenile and Domestic Relations Court, to determine if the family counseling service administered by the Diversion Department, could significantly reduce the recidivism rate among juvenile status offenders (JSOs). A retrospective design was employed in order to examine the records of 74 JSOs, who came in contact with the Intake Department of the Norfolk Juvenile Court in 1978. The recidivism rate was recorded, and data analyzed from a two year intervention period. Ss consisted of 37 JSOs who received family counseling (experimental group), and 37 JSOs who did not receive …

Recurrent Klebsiella Meningitis Following Trans-Sphenoidal Hypophysectomy For Nelson's Syndrome: Chloramphenicol Resistance During Relapse, Tom Madhavan, Daria Kiani, Louis Saravolatz, Keith Burch, Raymond C. Mellinger

Henry Ford Hospital Medical Journal

Three episodes of meningitis due to Klebsiella pneumoniae occurred in a young man following cerebral surgery. The patient had the features of Nelson's syndrome, and a chromophobe adenoma was removed by trans-sphenoidal resection. Intravenous chloramphenicol was effective in producing a temporary clinical response during the first episode of meningitis, but the organism became resistant to chloramphenicol during the second episode. Combined parenteral and intralumbar administration of gentamicin resulted in temporary improvement only. Subsequently, the subcutaneous cerebrospinal fluid (CSF) reservoir of Ommaya provided a safe, convenient way to administer prolonged intraventricular therapy which, combined with a definitive procedure to correct the …

Occult Cushing's Syndrome Presenting With Osteoporosis, M. Kleerekoper, Sudhaker D. Rao, B. Frame, R. D. Larocque, T. Feigelman, V. Matkovic, L. V. Avioli

Henry Ford Hospital Medical Journal

Osteoporosis is a frequent complication both of endogenous hypercortisolism and of long-term treatment with corticosteroids, but only rarely is it the major clinical feature with the more characteristic features absent or minimally present. In the two patients presented, hypercortisolism was uncovered only during routine evaluation of osteoporosis. This presentation is probably due to slow progression of the disease and is often associated with so-called black adenoma of the adrenal gland. Secondary causes should be sought in all patients with seemingly "senile" or "postmenopausal" osteoporosis.