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Development And Characterization Of Bulk Dsdna-Based Materials Using Biologically Derived Plasmid Dna, Wynter Amythyst Paiva Dec 2025

Development And Characterization Of Bulk Dsdna-Based Materials Using Biologically Derived Plasmid Dna, Wynter Amythyst Paiva

Doctoral Dissertations

Double-stranded DNA (dsDNA) exhibits many unique sequence-independent properties that remain underutilized in materials science. The exceptional length, solubility, biocompatibility, imageability, molecular recognition capabilities, and topological control of DNA makes it an ideal candidate for the creation of bespoke biomaterials and investigation of fundamental relationships in polymer physics. Unfortunately, translation of DNA-based materials from the microscale to macroscale has been hindered by source constraints and limitations in chemical modification of biologically derived DNA. This work seeks to expand the utility of dsDNA from the benchtop to real world applications. Establishing dsDNA as a commodity polymer will aid in the development of …


Open Repository @ Binghamton Monthly Additions And Top Downloads - November 2025, Caitlin Holton Dec 2025

Open Repository @ Binghamton Monthly Additions And Top Downloads - November 2025, Caitlin Holton

Library Created Resources

Newly added work in the Open Repository @ Binghamton (ORB) from 11/1/2025-11/30/2025. Top downloads from same time frame.


December 2025, Pacific Alumni Association Dec 2025

December 2025, Pacific Alumni Association

Alumni News & Events

No abstract provided.


An Analytics Framework For Healthcare Expenditure Forecasting With Machine Learning, John Wang, Shubin Xu, Yawei Wang, Houda El Bouhissi Dec 2025

An Analytics Framework For Healthcare Expenditure Forecasting With Machine Learning, John Wang, Shubin Xu, Yawei Wang, Houda El Bouhissi

Department of Hospitality and Tourism Faculty Scholarship and Creative Works

The United States healthcare system relies heavily on Medicaid, which serves nearly 80 million people and accounts for a substantial share of both state and federal budgets. This study employs a range of forecasting methods, including ARIMA, Holt's linear trend, polynomial regressions (degree 2 and 4), Prophet, and piecewise linear regression, as well as machine learning models such as random forest, gradient boosting, and support vector regression, to analyze the growth of Medicaid expenditures. Using data from 1966 to 2024, the analysis identifies historical patterns and evaluates model performance with Root Mean Squared Error (RMSE) and related metrics to project …


Ecotheology For Kids, Lana Glenn Dec 2025

Ecotheology For Kids, Lana Glenn

Theses

This project includes research into the eco-anxiety of children and how ecotheology may help ease the children’s minds. This project is meant as a sign of hope in the climate crisis; there are so many reasons to look forward to ecological improvements for the Earth. As adults, we should remind children of these reasons to be hopeful for the future. This 24-page book has illustrations with prayers to help calm the readers, while the cover is informational and inviting.


The Vampire In Video Games: Narrative Structures, Game Mechanics, And Cultural Significance, Ricardo Longo Minervino Dec 2025

The Vampire In Video Games: Narrative Structures, Game Mechanics, And Cultural Significance, Ricardo Longo Minervino

Theses

This thesis examines how vampires are represented in video games by analyzing narrative structures, game mechanics, and cultural meaning. Using the existing games of Vampyr, V Rising, Vampire: The Masquerade – Bloodlines, The Sims 4: Vampires, Skyrim: Dawnguard, Baldur’s Gate 3, and Bloodlines 2, the study identifies which design strategies successfully create an engaging and believable vampire experience for the player, as well as determining which development decisions could hurt the experience for players. Using formalism, symbolism, feminist methodology, and player reception theory, this thesis argues that vampire games function best when players confront moral dilemmas, experience consequences for feeding …


Cdk8/19 Inhibition Attenuates G1 Arrest Induced By Bcr-Abl Arrest Induced By Bcr-Abl Antagonists And Accelerates Death Of Chronic Myelogenous Leukemia Cells, Alvina I. Khamidullina, Margarita A. Yastrebova, Alexandra V. Bruter, Julia V. Nuzhina, Nadezhda E. Vorobyeva, Anastasia M. Khrustaleva, Ekaterina A. Varlamova, Alexander V. Tyakht, Iaroslav E. Abramenko, Ekaterina S. Ivanova, Maria A. Zamkova, Jing Li, Chang-Uk Lim, Mengqian Chen, Eugenia V. Broude, Igor B. Roninson, Alexander A. Shtil, Victor V. Tatarskiy Dec 2025

Cdk8/19 Inhibition Attenuates G1 Arrest Induced By Bcr-Abl Arrest Induced By Bcr-Abl Antagonists And Accelerates Death Of Chronic Myelogenous Leukemia Cells, Alvina I. Khamidullina, Margarita A. Yastrebova, Alexandra V. Bruter, Julia V. Nuzhina, Nadezhda E. Vorobyeva, Anastasia M. Khrustaleva, Ekaterina A. Varlamova, Alexander V. Tyakht, Iaroslav E. Abramenko, Ekaterina S. Ivanova, Maria A. Zamkova, Jing Li, Chang-Uk Lim, Mengqian Chen, Eugenia V. Broude, Igor B. Roninson, Alexander A. Shtil, Victor V. Tatarskiy

Faculty Publications

Imatinib mesylate (IM) and other BCR-ABL tyrosine kinase inhibitors (BCR-ABLi) are the mainstay of chronic myelogenous leukemia (CML) treatment. However, activation of circumventing signaling pathways and quiescence may limit BCR-ABLi efficacy. CDK8/19 Mediator kinases have been implicated in the emergence of non-genetic drug resistance. Dissecting the effects of pharmacological CDK8/19 inhibition on CML survival in response to BCR-ABLi, we found that a selective, non-toxic CDK8/19 inhibitor (CDK8/19i) Senexin B (SenB) and other CDK8/19i sensitized K562 cells to different BCR-ABLi via attenuation of cell cycle arrest. In particular, SenB prevented IM-induced upregulation of genes that negatively regulate cell cycle progression. SenB …


Regional Analysis Changes In The Salt Marsh: How The Past Is Influencing The Present, Elizabeth May Gorrill Dec 2025

Regional Analysis Changes In The Salt Marsh: How The Past Is Influencing The Present, Elizabeth May Gorrill

Master's Theses and Capstones

Salt marshes are critical coastal wetlands that provide valuable ecosystem services including coastal erosion control, carbon sequestration, water quality improvement, fisheries habitats, and recreational and economic opportunities for coastal communities. To better understand salt marshes and the changes occurring within the systems due to environmental and human factors, monitoring of established sites is conducted to look at variables such as vegetation cover, elevation, fauna, and vertical accretion. Methodological differences amongst monitoring efforts can result in data that has differing implications when analyzed and interpreted, so documentation of protocols (and any deviance from them) is imperative when bringing together datasets. The …


Digital Commons News: Updated Author Dashboard Available On Digital Commons, Alice Sherwood Dec 2025

Digital Commons News: Updated Author Dashboard Available On Digital Commons, Alice Sherwood

TMC Library Newsletter (2015-)

No abstract provided.


Book Review Of Douglass, J.A. (2021). Neo-Nationalism And Universities: Populists, Autocrats, And The Future Of Higher Education., Bhavika Sicka Dec 2025

Book Review Of Douglass, J.A. (2021). Neo-Nationalism And Universities: Populists, Autocrats, And The Future Of Higher Education., Bhavika Sicka

Journal of Comparative & International Higher Education

No abstract provided.


Improving Pharmacovigilance Via Systematic Gass Screening And Interdisciplinary Collaboration In The Outpatient Setting, Dustin Bower Dec 2025

Improving Pharmacovigilance Via Systematic Gass Screening And Interdisciplinary Collaboration In The Outpatient Setting, Dustin Bower

Doctor of Nursing Practice Projects

The goal of this Doctor of Nursing Practice (DNP) quality improvement project was to enhance pharmacovigilance practices among non-medical mental health providers (NMMHPs) in an outpatient psychiatric setting. The project addressed the issue of limited recognition and reporting of adverse drug reactions (ADRs) by NMMHPs, which can lead to delays in clinical intervention and compromise patient safety. To tackle this problem, a quasi-experimental, pre–post intervention design was employed. Two evidence-based strategies were implemented: (a) eight weekly collaborative training sessions that focused on identifying, documenting, and communicating ADRs, and (b) the integration of the Glasgow Antipsychotic Side-Effect Scale (GASS) into the …


Enhancing Provider Knowledge And Compliance With Diabetic Retinopathy Screening Through Education: A 4-Week Plan, Maureen Odemena Dec 2025

Enhancing Provider Knowledge And Compliance With Diabetic Retinopathy Screening Through Education: A 4-Week Plan, Maureen Odemena

Doctor of Nursing Practice Projects

Diabetic retinopathy (DR) is a leading cause of vision impairment that can be prevented if found and treated early. Inadequate provider knowledge and adherence to guidelines, and low referral rates for screening at the project site, highlighted the need for targeted training. Studies show that evidence-based education plans improve engagement in DR screening. This quality improvement (QI) project aimed to impact knowledge, self-efficacy, and compliance among healthcare providers (HCPs—nurse practitioners and physicians) and increase screening rates by implementing an American Diabetes Association (ADA) guideline-based education plan over 4 weeks. Based on the health belief model and Kurt Lewin’s change theory, …


Quality Improvement Project: Empowering Nurse Educators: Implementing A Mentoring Program For Professional Growth, Sarah Sugg Dec 2025

Quality Improvement Project: Empowering Nurse Educators: Implementing A Mentoring Program For Professional Growth, Sarah Sugg

Doctor of Nursing Practice Projects

With the ongoing nursing shortage, nursing education plays a vital role in shaping the future of healthcare through the preparation of competent and skilled nurses. Literature supports that a persistent challenge within nursing academia is the lack of structured mentoring programs to support novice nursing faculty transitioning into academic roles. This quality improvement project addressed this gap through the implementation of a structured, evidence-based mentoring program compared to informal mentoring. The purpose of the project was to empower novice nursing faculty with less than three years of teaching experience by enhancing teaching competence, confidence, job satisfaction, and retention. Guided by …


Quality Improvement Project: Increasing Breast Cancer Screening Rates Among Women Ages 40-74 At A Federally Qualified Health Center By Implementing A Provider Alert Tool, Tiny Stephens Dec 2025

Quality Improvement Project: Increasing Breast Cancer Screening Rates Among Women Ages 40-74 At A Federally Qualified Health Center By Implementing A Provider Alert Tool, Tiny Stephens

Doctor of Nursing Practice Projects

Breast cancer maintains its position as the leading cause of cancer-related death for women worldwide and remains the second deadliest cancer among female patients in the United States (Centers for Disease Control, 2024). The screening rates at Federally Qualified Health Centers (FQHCs), which serve medically underserved communities, remain lower than national benchmarks, thus putting their patients at risk for receiving late-stage cancer diagnoses. This quality improvement project implemented an evidence-based electronic medical record (EMR) provider alert tool at a Northeast Georgia FQHC to address a baseline mammogram order compliance rate falling below national standards at 45%. The project aimed to …


Quality Improvement Project Nursing Student Retention Strategies: A Focus On Peer Mentoring, Anh Vittoria Dec 2025

Quality Improvement Project Nursing Student Retention Strategies: A Focus On Peer Mentoring, Anh Vittoria

Doctor of Nursing Practice Projects

The nursing shortage remains a concern in healthcare. Increasing the number of students who complete nursing programs and enter the profession can help with the demand for nurses in the workforce. Nursing programs face challenges with student retention, which limits the number of nurses entering the profession. The quality improvement project aimed to examine the effects of a peer mentorship program on first-year associate degree nursing students’ perception of support and course completion rates. The purpose is to impact student retention and sense of support in an Associate Degree Nursing Program (ADN) through peer mentorship. The project was guided by …


Quality Improvement Project Enhancing Documentation Practices In Community Mental Health Clinics, Carol Parker Dec 2025

Quality Improvement Project Enhancing Documentation Practices In Community Mental Health Clinics, Carol Parker

Doctor of Nursing Practice Projects

Accurate and timely documentation are essential for safe, high-quality care in community mental health settings. This quality improvement (QI) project addressed inconsistent documentation practices among licensed, unlicensed, and Qualified Mental Health Specialist (QMHS) staff at an outpatient clinic. The purpose of the QI project was to implement and assess a structured in-service training program using the Accountable Health Communities–Health-Related Social Needs (AHC-HRSN) screening and documentation tool to improve staff knowledge, enhance documentation accuracy, and facilitate care coordination. Guided by the Iowa Model of Evidence-Based Practice and Lewin’s Change Management Model, a pre- and post-intervention design was used. Fifteen staff members …


Enhancing Mental Health Providers' Approach To Medication Adherence In Schizophrenia Patients Using Motivational Interviewing Techniques., Jacinta Madu Dec 2025

Enhancing Mental Health Providers' Approach To Medication Adherence In Schizophrenia Patients Using Motivational Interviewing Techniques., Jacinta Madu

Doctor of Nursing Practice Projects

Medication non-adherence among individuals with schizophrenia remains a persistent challenge that undermines symptom management and increases relapse and hospitalization rates. This quality improvement (QI) project aimed to evaluate the effect of Motivational Interviewing (MI) training on provider knowledge and confidence in promoting medication adherence within an outpatient mental health clinic. Guided by Lewin’s Change Theory and the Plan-Do-Study-Act (PDSA) framework, a quasi-experimental pre–post design was used. Six providers, including psychiatric nurse practitioners, therapists, a psychiatrist, and a registered nurse, participated in a structured MI training session incorporating didactic instruction and role-play exercises. Data were collected using pre- and post-intervention surveys …


Quality Improvement Project: Effect Of Multi-Level Student Collaboration On Clinical Judgment In High-Fidelity Simulation, Jillian Carroll Dec 2025

Quality Improvement Project: Effect Of Multi-Level Student Collaboration On Clinical Judgment In High-Fidelity Simulation, Jillian Carroll

Doctor of Nursing Practice Projects

There is a gap in undergraduate nursing curriculum on incorporating collaboration and communication into patient care, leading to a lack of competence and confidence in novice practice. Using collaboration in high-fidelity simulation, students gain real-world exposure and opportunities to communicate and make independent decisions. Using Kotter’s eight-step change theory, this project addresses the limited exposure to collaboration by implementing purposeful interdisciplinary collaboration within high-fidelity simulation to improve undergraduate nursing students’ confidence and competence in nursing practice. This will build on Patricia Benner’s novice-to-expert theory and help advance Associate Degree Nursing (ADN) students into a safe and effective novice year of …


Quality Improvement Project: Impact Of A Brief Mindfulness-Based Stress Reduction Program For Healthcare Providers Who Evaluate Veterans, Peng Anderson Dec 2025

Quality Improvement Project: Impact Of A Brief Mindfulness-Based Stress Reduction Program For Healthcare Providers Who Evaluate Veterans, Peng Anderson

Doctor of Nursing Practice Projects

Long-term stress can lead to healthcare provider burnout. Mindfulness-based interventions, even when shortened, may provide a promising and innovative method to reduce stress and prevent burnout. Research on mindfulness programs has demonstrated significant benefits for both providers and patients. This quality improvement project aims to evaluate the effect of a brief mindfulness-based stress reduction program (MBSR) for providers who evaluate veterans on the variable of mindfulness awareness compared to current site practice. Lewin’s change management model and Peplau’s Interpersonal Relations Theory were used. Plan-Do-Study-Act was the implementation framework applied. The design was pretest-posttest using the Mindful Attention Awareness Scale (MAAS). …


Current Knowledge And Perspectives Of Relative Energy Deficiency In Sport In An Athletic Environment, Meredith Rebecca Morgan Dec 2025

Current Knowledge And Perspectives Of Relative Energy Deficiency In Sport In An Athletic Environment, Meredith Rebecca Morgan

Electronic Theses and Dissertations

Sport performance personnel are in a unique position to directly impact athletes. While the primary individuals who manage athlete health are physicians, sport dietitians, and certified athletic trainers, sport coaches and strength and conditioning coaches also play an impactful role in an athlete’s performance and well-being. Using an original survey, this study investigated REDs knowledge by certified athletic trainers, strength and conditioning coaches and sport coaches. The survey was employed to assess sport performance professionals’ general knowledge of Relative Energy Deficiency in Sport (REDs) and low energy availability (LEA) and opinions on the role of health professionals in REDs identification, …


Discover Consensus: Ai For Academic Research, Joanne Romano Dec 2025

Discover Consensus: Ai For Academic Research, Joanne Romano

TMC Library Newsletter (2015-)

Consensus is an AI-powered search engine for academic research that scans 200+ million academic papers and uses language models to help find, understand, and synthesize peer-reviewed literature.

Start your journey by creating your Consensus account!


Processing Self, Ethan B. Mckellar Dec 2025

Processing Self, Ethan B. Mckellar

All Theses

Processing Self is a body of sculptural and utilitarian ceramic work that explores the intersection of the materiality of clay with the expression of grief and vulnerability. In this work I utilize the process of building unstable ceramic vessels and the communal action of wood firing to translate the experiences of grief and care into physical forms. As I build, I manipulate the clay to its limits, allowing it to falter under its own weight, and display the breakage and damage. By committing to support each vessel through its creation, I make a promise to persevere, echoing the commitment I …


Parental Experiences With Financial Toxicity In The Pediatric Intensive Care Unit: A Phenomenological Research, Sohrab Alexander Sardual Dec 2025

Parental Experiences With Financial Toxicity In The Pediatric Intensive Care Unit: A Phenomenological Research, Sohrab Alexander Sardual

Dissertations and Theses (Open Access)

Background: Parents of children admitted to the pediatric intensive care unit (PICU) encounter multiple stressors; however, there is a need to further understand their experiences with financial toxicity. Understanding parents’ experiences and perspectives on how they can be assisted is a critical first step to formulating interventions to help parents deal with financial toxicity.

Aims: The aims of this study are (a) to describe the experiences with financial toxicity of parents with critically ill children admitted to the PICU and (b) to explore parents’ perspectives on how they can be assisted in dealing with financial toxicity.

Methods: A phenomenological qualitative …


University Of Nebraska At Omaha Commencement: December 2025, University Of Nebraska At Omaha Dec 2025

University Of Nebraska At Omaha Commencement: December 2025, University Of Nebraska At Omaha

Commencement Programs

No abstract provided.


Developing An Intergroup Dialogue Training Program For Organizational Leadership: A Pilot Partnership With The Greater Omaha Chamber, Manasi Kate Dec 2025

Developing An Intergroup Dialogue Training Program For Organizational Leadership: A Pilot Partnership With The Greater Omaha Chamber, Manasi Kate

Communications Theses, Dissertations, and Student Creative Activity

This graduate project proposes the development and pilot implementation of a structured Intergroup Dialogue (IGD) training program designed to enhance communication and leadership capabilities within complex organizational environments. In response to the escalating challenge of social polarization, which systematically impedes collaboration and innovation, this initiative created an adaptable curriculum for leaders in all organizational sectors and settings.

The program was divided into six sessions, each of which led participants through themes such as identity, power, storytelling, systems, and authentic social leadership, with the goal of increasing self-awareness and collective understanding. The program development plan includes a rigorous phase of curriculum …


Of The Freedom Famine In Palestine, Ibtisam Barakat Dec 2025

Of The Freedom Famine In Palestine, Ibtisam Barakat

International Dialogue

In this searing essay, poet and author Ibtisam Barakat bears witness to what she names the “Freedom Famine” in Gaza—a deliberate, decades-long deprivation of basic human rights culminating in the catastrophic conditions of 2025. Writing from the United States while in conversation with Gazan author Omar Hammash, Barakat juxtaposes their drastically unequal realities: her safety and his daily encounters with death, displacement, and starvation. Through Hammash’s testimony—delivered amid constant bombardment and interrupted by news of a friend’s killing—Barakat documents the collapse of Gaza’s infrastructure, the mass targeting of aid workers, the lethal failures of international relief, and the killing of …


Editorial – Dec 2025, Edwin Van Teijlingen, Rafat Jan Dec 2025

Editorial – Dec 2025, Edwin Van Teijlingen, Rafat Jan

Journal of Asian Midwives (JAM)

No abstract provided.


Effect Of Focussing On Anastatica Hierochuntica Flower On Labour Pain, Duration Of Labour And Perceived Fatigue During Labour: Randomized Controlled Study, Emine Koç, Şükran Başgöl, Sümeyye Bal, Sabire Kirtiloğlu Dec 2025

Effect Of Focussing On Anastatica Hierochuntica Flower On Labour Pain, Duration Of Labour And Perceived Fatigue During Labour: Randomized Controlled Study, Emine Koç, Şükran Başgöl, Sümeyye Bal, Sabire Kirtiloğlu

Journal of Asian Midwives (JAM)

Background: Maternal fatigue and pain during labour can adversely affect the health of the mother, fetus, and newborn. Anastatica hierochuntica is a plant traditionally used in some cultures during childbirth rituals. When placed in water, the dried flower gradually unfolds and symbolically represents the opening of the uterus and birth canal. This study aimed to investigate the effect of focusing on the Anastatica hierochuntica flower during labour on labour pain, duration, and perceived fatigue.
Methods: This randomized controlled trial was conducted in the delivery unit of a mother-friendly hospital with 119 participants 60 in control group and 59 in intervention …


Factors Associated With Preterm Premature Rupture Of Membranes: A Case-Control Study In A Tertiary Hospital In Kabul, Afghanistan, Atia Sharif Nadi, Freshta Sharif Tawakkuli, Zainab Sharif Ezadi, Sayed Murtaza Sadat Hofiani, Shoaib Murtaza Sadat Naeemi, Ahmad Komail Frogh Dec 2025

Factors Associated With Preterm Premature Rupture Of Membranes: A Case-Control Study In A Tertiary Hospital In Kabul, Afghanistan, Atia Sharif Nadi, Freshta Sharif Tawakkuli, Zainab Sharif Ezadi, Sayed Murtaza Sadat Hofiani, Shoaib Murtaza Sadat Naeemi, Ahmad Komail Frogh

Journal of Asian Midwives (JAM)

Background: It is essential to identify preterm premature rupture of membranes (PPROM) and its associated risk factors to reduce its impact. This study aims to find the demographic, reproductive, and obstetric factors associated with PPROM among women in Kabul, Afghanistan.
Methods: This case-control study was conducted over six months in 2023 at a tertiary hospital in Kabul, Afghanistan. We included 40 cases of PPROM and 80 controls without PPROM in this study. We used structured questionnaires to collect demographic, reproductive, and obstetric characteristics of the participants. To find the factors associated with PPROM, Logistic regression was performed using IBM SPSS …


A Scoping Review Of Maternal Active Smoking During Pregnancy And Low-Birth Weight, Naomi Sondang, Nindi Oktavia, Qorinah Estiningtyas Sakilah Adnani, Lani Gumilang, Hadi Susiarno, Victor Abiola Adepoju Dec 2025

A Scoping Review Of Maternal Active Smoking During Pregnancy And Low-Birth Weight, Naomi Sondang, Nindi Oktavia, Qorinah Estiningtyas Sakilah Adnani, Lani Gumilang, Hadi Susiarno, Victor Abiola Adepoju

Journal of Asian Midwives (JAM)

Background: Low-birth weight (LBW; < 2.5 kg) infants are at increased risk of early mortality, impaired growth, neuro-developmental delay and chronic disease later in life. Maternal behavior, especially cigarette smoking, remains one of the most modifiable determinants of birth weight. We therefore synthesized recent evidence on the association between active maternal smoking during pregnancy and LBW.
Methods: Following PRISMA guidance, we systematically searched PubMed, Scopus and ScienceDirect for the period January 2020 to 31 January 2025 for English-language observational studies that quantified the relationship between active prenatal smoking and LBW. Risk of bias was appraised, and findings were summarized narratively.
Results: In total 26,650 papers were found and eight eligible studies (four cohort, three cross-sectional, one case-control) from Asia, Europe and the Middle East were included. Across all designs and exposure metrics—self-report, exhaled carbon-monoxide, urinary cotinine, and cord-blood DNA-methylation, active smoking was consistently associated with …