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Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

The Effectiveness Of Stimulation Therapy For The Cognitively Impaired Elderly, Sylvia H. Old

Community & Environmental Health Theses & Dissertations

The effectiveness of stimulation therapy for the cognitively impaired elderly living in an institution was assessed. Residents with varying degrees of cognitive impairment were treated with twenty, thirty-minute daily periods of reality orientation, reminiscence, resocialization, remotivation, and other stimulating therapies and were compared with a control group_ receiving no intervention. Treatment effects were assessed with a variety of instruments reflecting functioning across several domains. Included were ability to perform both basic self-care functions and activities of daily living, cognitive performance, affect, and satisfaction with the care received and the living environment in the nursing home. The experimental group was divided …

Recovery Of Helminths From Prehistoric Feces: The Cultural Ecology Of Ancient Parasitism, Karl J. Reinhard

Karl Reinhard Publications

Several helminth parasites have been recovered from archaeological sites on the Colorado Plateau. These include Ascaris, Trichuris, Enterobius, Moniliformis, and tapeworms in the families Hymenolepidae and Taeniidae. The recovery of these animals demonstrates that cross-temporal: comparison of parasitism between different prehistoric lifestyles is possible. Such comparison might elucidate the effects of changing lifestyle and subsistance pattern on human parasitism.

Desiccated feces recovered from archaelogical deposits were studied. Hunter-gatherer feces were selected from Dust Devil Cave in southeastern Utah. Agriculturalist feces were studied from Antelope House, a cave site in northeastern Arizona, and Salmon Ruins, a Pueblo …

Current Concepts Of Metabolic Functional Imaging With Positron Emitters, John W. Keyes Jr.

Henry Ford Hospital Medical Journal

Positron emitting radionuclides have unique properties that make them nearly ideal as radioactive tracers for in vivo metabolic studies. Using positron emission tomographic (PET) scanning and positron-labeled radiopharmaceuticals, one can study local glucose metabolism in tissues, blood flow, oxygen utilization, protein synthesis, and many other functions noninvasively in normal subjects and patients who have various diseases. A review of some of these techniques and the relative advantages and problems associated with the PET approach is presented.

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Cerebral Angiography In Posterior Fossa Revascularization, Roushdy S. Boulos, Suresh Patel, Bharat Mehta, Clifford Jack

Henry Ford Hospital Medical Journal

With advances in microsurgical techniques and refinement of cerebral angiography, many new surgical approaches for the treatment of vertebrobasilar insufficiency (VBI) have been developed. Detailed selective cerebral angiography is essential for confirming the clinical diagnosis, for demonstrating the exact anatomical and topographical vascular pathology, and for deciding on the best surgical procedure. Angiography is recommended to evaluate treated patients both in the early and late postoperative periods. It is an essential element of any future randomized study to assess the value of surgical vs medical treatment of patients with VBI. The benefits of cerebral angiography far outweigh the small risk …

Digital Radiography: A Review, David J. Kastan, Laurens V. Ackerman, Peter J. Feczko, Gordon H. Beute

Henry Ford Hospital Medical Journal

The fully digital radiology department remains a radiologist's dream. The technology necessary for implementation does not yet exist other than in prototype form. When the technology catches up with the radiologist's ideas, many new capabilities will exist. Electronically stored images will be available for viewing wherever a computer terminal exists. The problem of film loss would be nonexistent. Images could be quickly transmitted for interpretation via microwave networks to sites far removed from where they are acquired. Patient radiation exposure would decrease. Computers would help decrease perception errors and would assist in image interpretation. It may be ten years before …

Preliminary Experience With Digital Subtraction Angiography In Cardiac Evaluation, Matthew W. Burke, P. C. Shetty, Rajinder Sharma, James F. Brymer, Fareed Khaja

Henry Ford Hospital Medical Journal

iVe report our initial experience using digital subtraction angiography (DSA) techniques for cardiac evaluation. DSA of the heart may be performed with intravenous or right atrial injection of contrast medium (IVDSA) and with left ventricular or aortic root contrast injection (lADSA). The right ventricle and the atria are best demonstrated by IVDSA, while the left ventricle and coronary arteries are best demonstrated by lADSA. The advantages and disadvantages of DSA ofthe bean are discussed. Present equipment limitations restrict the routine use of cardiac DSA, but these should be overcome with advances in technology.

Nuclear Magnetic Resonance: Current And Future Clinical Applications, Jerry W. Froelich, David O. Hearshen, Robert D. Halpert, Suresh Patel

Henry Ford Hospital Medical Journal

Nuclear magnetic resonance has evolved from a laboratory analytical tool to become a rapidly developing discipline in clinical medicine. We present a brief historical overview, an introduction to the basic principles of the phenomenon, and a statement of the current status of clinical imaging. We have elected to use the traditional terminology nuclear magnetic resonance to refer to the imaging component of the field rather than the American College of Radiology (ACR) modification magnetic resonance. We do this out of respect for the founders of the field.

The Strange Story Of Jay Mclean, The Discoverer Of Heparin, Conrad R. Lam

Henry Ford Hospital Medical Journal

Since 1939, the use of heparin has become widespread in the prevention of postoperative thrombosis and embolism and is the basis for modern open-heart surgery. What is not generally known is the story of Jay McLean, the second-year medical student at Johns Hopkins who is given credit for the original discovery. McLean's first scientific publication concerning the use of heparin does not contain the word "heparin," and not until 25 years later did McLean publish a short paper about heparin. Some personal letters and other research have indicated a checkered career. He was trained as a surgeon in the Halsted …

Central Pontine Myelinolysis In A Patient With Adrenal Insufficiency, John E. Brunner

Henry Ford Hospital Medical Journal

Central pontine myelinolysis is a demyelinating process that has occurred in association with rapid correction of hyponatremia. Presented here is the case of a patient who had adrenal insufficiency and who experienced signs of central pontine myelinolysis after rapid correction of severe hyponatremia (28 mEq/L of sodium administered in the first 24 hours, initial serum sodium level 97mEq/L). Sustained hyponatremia and the use of intravenous contrast material after hyponatremia correction are discussed as possible risk factors in the development of central pontine myelinolysis.

In Defense Of The Pickwickian Syndrome, Howard Markel

Henry Ford Hospital Medical Journal

No abstract provided.

Diagnosis Of Hepatic Portal Venous Gas By Computed Tomography: Role Of Intravenous Contrast Material, Allan M. Haggar, Michael A. Sandler, Martin L. Gross, Beatrice L. Madrazo

Henry Ford Hospital Medical Journal

We describe a case of hepatic portal venous (HPV) gas. The diagnosis was assisted by findings of computed tomography (CT). The HPV gas resulted from a diverticular abscess in a patient who had a stable clinical course. If the possibility of HPV gas exists, scanning without intravenous administration of contrast material should be performed. If postcontrast scans alone are obtained, the opacified portal blood may mask small amounts of HPV gas, as was true in this case. Also, postcontrast scans can easily distinguish HPV gas from air within the biliary tree if findings of precontrast scans are equivocal.

The Invalidity Of Monitoring Transcutaneous Oxygen Tension In Patients Who Have Chronic Renal Failure, John R. Armstrong, Thomas W. Kreps, William A. Conway, Francis Dumler, John Popovich Jr.

Henry Ford Hospital Medical Journal

We assessed accuracy of monitoring transcutaneous oxygen tension (PtcO2) in patients with chronic renal failure (CRF). Sixteen stable individuals undergoing chronic maintenance hemodialysis were studied. Correlations between simultaneously determined PtcO2 and arterial oxygen tension (PaO2) were made both before and during dialysis. Comparisons were made with a group of 22 consecutive patients in whom respiration was mechanically assisted, who were hemodynamically stable (urine output greater than 30 mL/hour, pulse less than 130 beats/min, and mean arterial blood pressure greater than 80 mm Hg in the absence of pressor agents), and who had normal renal function.

Among CRF patients, the correlation …

Editorial: In Defense Of Historians, Conrad R. Lam

Henry Ford Hospital Medical Journal

No abstract provided.

Ua37/30/2 Wku Research Notecards - F Topics, Lowell Harrison

Faculty/Staff Personal Papers

Notecards created by Lowell Harrison while researching his book Western Kentucky University. The cards transcribed below are for 259 topics beginning with F ranging from Faculty - Hunt to Future of Education.

Effects Of Water Quality And Water Quantity On Nutritional Status: Findings From A South Indian Community, James R. Hébert

Faculty Publications

Quantitative assessments of the relative effects on health of various aspects of water supply are virtually absent from the literature. Despite the lack of information, resources are being allocated throughout the developing world, for projects related to water and sanitation. The present study was designed specifically to overcome many of the methodological problems that other researchers have faced. Data were collected concerning the nutritional status of 627 children in three urban communities in South India. Information was also collected on water quality, water quantity, household sanitation, socioeconomic conditions, and housing. A statistical technique is presented that allows for controlling potential …

Body Composition And Its Outcomes And Management In Multiple Sclerosis: Narrative Review, H W Van Landuyt, J Boelaert, P Piot, L Verbist

Faculty, Staff and Student Publications

Background: There is emerging interest in obesity and its prevalence, outcomes, and management in people with multiple sclerosis (MS). Body mass index (BMI) is the traditional marker of obesity in MS, whereas body composition, inclusive of specific body tissue compartments (e.g., fat, bone, and muscle), is often overlooked despite its relevance.

Objective: This narrative review (a) underscored the use and utility of dual-energy X-ray absorptiometry (DEXA) as an accurate and reliable measure of body composition; (b) thematically analyzed and synthesized the current evidence regarding body composition (using DEXA); and (c) determined gaps to be addressed in future research.

Methods: The …

Linkage Data Excluding A Locus For Multiple Endocrine Neoplasia Type 2 Syndromes From The Distal Part Of The Short Arm Of Chromosome 11, Kenneth K. Kidd, Susan D. Kruger, Daniela S. Gerhard, Judith R. Kidd, David Housman, Joseph M. Gertner

Henry Ford Hospital Medical Journal

A study designed to identify the location of a gene for multiple endocrine neoplasia type 2 (MEN-2) is being performed using a single large family segregating for MEN-2A. Here we report our initial results using a set of DNA restriction fragment length polymorphisms spanning a 40 cM segment of the short arm of human chromosome 11. The locus for MEN-2 in this family is excluded from this entire region which includes an oncogene, c-Ha-ras-1, two hormone loci, insulin and parathyroid, and the five hemoglobin genes in the beta hemoglobin gene duster. This is the first exclusion of such a large …

Multiple Endocrine Neoplasia Type 2 Syndromes: Historical Perspectives, John H. Sipple

Henry Ford Hospital Medical Journal

No abstract provided.

Screening For Hereditary Medullary Cancer In Denmark, Kristian Emmertsen

Henry Ford Hospital Medical Journal

Screening of first-degree relatives of patients with medullary thyroid cancer (MTC) gave normal values of pentagastrin-stimulated serum calcitonin and 24-hour urinary catecholamine levels in the relatives of 18 of 22 patients. This result is considered to be valid evidence for sporadic MTC. Absence of C-cell hyperplasia maybe another indication of sporadic MTC. Four hereditary MTCs were represented by one fully expressed MEN-2B patient without affected relatives, one fully expressed MEN-2A case in one family, and two first cousins with MTC as the only MEN-2A lesion in another family. Fourteen relatives of the MEN-2A patients had elevated serum calcitonin levels, and …

A French Canadian Family With Multiple Endocrine Neoplasia Type 2 Syndromes, Maurice B. Verdy, Marcel Cadotte, Walter Schurch, William C. Sturtridge, Jacques Cantin, Andrée M. Weber, André Lacroix, Cynthia Forster-Gibson

Henry Ford Hospital Medical Journal

No abstract provided.

Genetic Studies Of Multiple Endocrine Neoplasia Type 2 Syndromes: A Workshop Commentary, Nancy E. Simpson

Henry Ford Hospital Medical Journal

No abstract provided.

Caring For The Sick Poor: The State Almshouse At Bridgewater, 1854-1887, Lucille O'Connell

Bridgewater Review

The number of helpless poor in Massachusetts increased during the period of the 1840s, and the problem was greatly magnified by Irish immigration to the United States. Too large a problem to be solved on the local level, the Board of Commissioners of Alien Passengers recommended, in 1852, that the State establish three almshouses. Accordingly, the institutions were established at Bridgewater, Monson to the west, and Tewksbury to the north of Boston, and were opened in May 1854. By the end of the first year the number of inmates far exceeded expectations.

Automating The Expertise Of The Neuropsychologist, Kenneth M. Adams, Gregory G. Brown

Henry Ford Hospital Medical Journal

No abstract provided.

Distributed Computing In A Hospital Environment, Steven R. Lund, Laurens V. Ackerman, James B. Martin

Henry Ford Hospital Medical Journal

Obtaining appropriate information in a timely fashion in medical practice has always been a burden for the practitioner. In a large hospital which undertakes major computer projects, this burden is intensified because information is not always available in a form directly usable by the physician or support personnel; it is now accumulated on diverse magnetic media where it is moved and processed as electronic pulses. This paper describes a solution which freely allows continued automation at different rates throughout a large hospital while expediting the movement of information where it is needed in a form understandable by the recipient.

A Microcomputer Database In A Clinical Environment, Dennis R. Ownby, Thomas A. Burnett

Henry Ford Hospital Medical Journal

No abstract provided.

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Immunology Of The Acquired Immunodeficiency Syndrome, Patrick W. Mclaughlin, Carl B. Lauter

Henry Ford Hospital Medical Journal

The Acquired Immunodeficiency Syndrome (AIDS) first recognized in 1981, has been extensively studied, and the most recent studies have demonstrated that its defects extend well beyond the apparent deficient cell-mediated immunity to include humoral immunity, autoimmunity, and abnormal immunoregulation. The recent discovery of a retrovirus, HTLV III, as a possible etiologic agent is discussed in relation to other viruses known to cause immunodeficiency. Simian AIDS, an animal model of virus-induced immunodeficiency, is also discussed. Recommendations are made regarding the interpretation and limitations of immune testing in AIDS, including a discussion of how apparently healthy homosexuals and groups at risk develop …

Congenital Seminal Vesicle Cyst: A Specific Diagnosis By Computed Tomography, Leo Drolshagen, Michael A. Sandler

Henry Ford Hospital Medical Journal

Computed tomography (CT) has been shown to be of great value in the assessment of the urinary tract. However, this modality has been primarily used in the evaluation of renal masses and the staging of urinary tract carcinomas. It may also be useful in less common abnormalities, such as mesonephric duct anomalies including congenital seminal vesicle cysts. These lesions are associated with renal agenesis and may produce urinary tract symptoms, or be discovered incidentally. We present a case of a congenital vesicle cyst associated with ipsilateral renal agenesis with characteristic CT findings allowing for a specific diagnosis.