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The Effects Of Lipopolysaccharide-Induced Neuroinflammation On Learning And Forgetting In Juvenile Rats, Michele Barry May 2016

The Effects Of Lipopolysaccharide-Induced Neuroinflammation On Learning And Forgetting In Juvenile Rats, Michele Barry

Seton Hall University Dissertations and Theses (ETDs)

The inability to remember events experienced very early in life is referred to as Infantile Amnesia (IA) and has been observed in both humans and animals. Over the years interest in the phenomenon waned, but has recently increased with the discovery of new neurobiological methods to study brain function (e.g., Callaghan, Li & Richardson, 2014). The neurobiological mechanism behind IA has yet to be determined, but several innovative theories have been developed with these new research methods. The neurogenesis hypothesis theorizes that increased neurogenesis during early development disrupts previously established memories. The hippocampus, an area that mediates both the memory …


A Randomized Controlled Trial Of An Integrated Brain, Body, And Social Intervention For Children With Adhd, Stephanie D. Smith, Lawrence A. Vitulano, Liliya Katsovich, Shuaixing Li, Christina Moore, Fenghua Li, Heidi Grantz, Xixi Zheng, Virginia Eicher, Selin Aktan Guloksuz, Yi Zheng, Jinxia Dong, Denis G. Sukhodolsky, James F. Leckman May 2016

A Randomized Controlled Trial Of An Integrated Brain, Body, And Social Intervention For Children With Adhd, Stephanie D. Smith, Lawrence A. Vitulano, Liliya Katsovich, Shuaixing Li, Christina Moore, Fenghua Li, Heidi Grantz, Xixi Zheng, Virginia Eicher, Selin Aktan Guloksuz, Yi Zheng, Jinxia Dong, Denis G. Sukhodolsky, James F. Leckman

Faculty Publications

Objective: This study evaluated the efficacy of an Integrated Brain, Body, and Social (IBBS) intervention for children with ADHD. Treatment consisted of computerized cognitive remediation training, physical exercises, and a behavior management strategy.

Method: Ninety-two children aged 5 to 9 years with ADHD were randomly assigned to 15 weeks of IBBS or to treatment-as-usual. Primary outcome measures included blinded clinician ratings of ADHD symptoms and global clinical functioning. Secondary outcome measures consisted of parent and teacher ratings of ADHD and neurocognitive tests.

Results: No significant treatment effects were found on any of our primary outcome measures. In terms of secondary …


Working Memory Impairments In Chromosome 22q11.2 Deletion Syndrome: The Roles Of Anxiety And Stress Physiology, Ashley F. P. Sanders May 2016

Working Memory Impairments In Chromosome 22q11.2 Deletion Syndrome: The Roles Of Anxiety And Stress Physiology, Ashley F. P. Sanders

LSU New Orleans Theses and Dissertations

Stress and anxiety negatively impact the working memory system by competing for executive resources. Broad memory deficits have been reported in individuals with chromosome 22q11.2 deletion syndrome (22q11.2DS). We investigated anxiety and physiological stress reactivity in relation to visuospatial working memory impairments in 20 children with 22q11.2DS and 32 typically developing children (M = 11.10 years, SD = 2.95). Results indicate reduced post-stress RSA recovery and overall increased levels of cortisol in children with 22q11.2DS. Additionally, anxiety mediated the relationship between 22q11.2DS and visuospatial working memory impairment. However, there was no indication that stress response physiology mediated this association. …


Caffeine Combined With Sedative/Anesthetic Drugs Used In Neonatal Medicine And Apoptotic Neurotoxicity In Developing Mouse Brain, Omar Hosea Cabrera May 2016

Caffeine Combined With Sedative/Anesthetic Drugs Used In Neonatal Medicine And Apoptotic Neurotoxicity In Developing Mouse Brain, Omar Hosea Cabrera

Dissertations

Each year, millions of premature babies are exposed to sedative/anesthetic drugs (SADs) in the neonatal intensive care unit (NICU). Acute exposure to SADs triggers widespread apoptosis in the developing brain of rodents and non-human primates. Furthermore, premature infants are administered caffeine (CAF) to treat respiratory dysfunction. Mounting evidence suggests that CAF may be neurotoxic and, when given in combination with SADs, potentiates SAD-induced cell death. However, the apoptotic interaction of CAF and SAD co-exposure is poorly understood. In a series of studies, I report that CAF combined with the NICU SADs midazolam, ketamine, or fentanyl is more neurotoxic to the …


An Analysis Of Canine Processing Of Stimulus Compounds Varying In Light And Sound Intensity, Katherine O. Compitus May 2016

An Analysis Of Canine Processing Of Stimulus Compounds Varying In Light And Sound Intensity, Katherine O. Compitus

Theses and Dissertations

A dog was trained to respond deferentially to two light-sound compounds. The dog was then tested with combinations of additional light and sound intensities. The dog appeared to use the information provided by both stimulus dimensions. This research is relevant to the understanding of information processing, specifically categorization and generalization.


The Nerve: Associations Between Perceived Parenting Style And Coping With Stress, Lauren Mcgrew May 2016

The Nerve: Associations Between Perceived Parenting Style And Coping With Stress, Lauren Mcgrew

Undergraduate Theses

Throughout a lifetime, women are twice as likely as men to develop an anxiety disorder. Several factors – biological, psychological, and social/environmental – are involved in the mechanisms of anxiety. The present study was designed with particular interest in the association between parents’ parenting styles and daughter anxiety, specifically paternal influences in correlation with how daughters cope with stress. Previous studies suggest that anxious tendencies in parents can be transferred to their children (Ballash, Leyfer, Buckley, & Woodruff-Borden, 2006). Studies have also identified three main parenting styles – authoritarian, authoritative, and permissive – which may also play a role in …


Examination Of Cue-Induced Nicotine Withdrawal Among Humans, Kathleen R. Owens May 2016

Examination Of Cue-Induced Nicotine Withdrawal Among Humans, Kathleen R. Owens

Senior Honors Projects, 2010-2019

There is copious research investigating the effect of environmental cues on the maintenance of drug behavior in animals, but sparse data exist with regard to humans. In our study, we examined 6 dependent cigarette smokers from James Madison University. We paid participants to use novel lighters that served as audible/tactile cues. After 2 weeks, participants returned to the lab satiated with nicotine for their testing session in which they were presented with the same cue and immediately completed a multiple-choice procedure (MCP) that measured their preferences by offering choices regarding money or the ability to take a cigarette break. Results …


Effects Of Modeling Varied Responses And Programming Lag Contingencies On Varied Responding During Discrete-Trial Instruction, Sean P. Peterson May 2016

Effects Of Modeling Varied Responses And Programming Lag Contingencies On Varied Responding During Discrete-Trial Instruction, Sean P. Peterson

Theses & Dissertations

Children with autism often require direct instruction to learn skills (e.g., discrete-trial instruction [DTI]). Despite its advantages, DTI has been criticized for producing rote responding (e.g., Cihon, 2007). Although there is little research supporting this claim, if true, this may be problematic given the propensity of children with autism to engage in restricted and repetitive behavior (American Psychiatric Association, 2013). In Experiment 1, we evaluated the effects of modeling rote versus varied target responses during DTI on producing varied responding and efficiency of skill acquisition in learning intraverbal categorizations. For all four children, all increases in varied responding were temporary, …


The Achievement Gap And Students Living In Poverty: The Role Of Core Self-Evaluation And Transformational Leadership In Teachers, India Harris May 2016

The Achievement Gap And Students Living In Poverty: The Role Of Core Self-Evaluation And Transformational Leadership In Teachers, India Harris

Dissertations, 2014-2019

Research has shown that the combination of locus of control, self-efficacy, self-confidence, and emotional stability is a good predictor of life success. Until now, this second order factor, called core self-evaluations (CSE) has only been studied in adults. Findings from this study, showed levels of CSE were significantly and positively connected with academic achievement for middle and elementary aged students. CSE appears to play to a similar role between students and academic achievement as it plays with adults and job performance. In this study, the dimensions of transformational leadership were applied to teacher behaviors and students were grouped based on …


The Effects Of Chronic Partial Sleep Deprivation And Chronic Voluntary Alcohol Consumption On Δfos B Accumulation, Kristian Ponder May 2016

The Effects Of Chronic Partial Sleep Deprivation And Chronic Voluntary Alcohol Consumption On Δfos B Accumulation, Kristian Ponder

Masters Theses, 2010-2019

The present study explores the relation between sleep restriction and alcohol use and the neural substrates that result from chronic behaviors. Accumulation of the transcription factors ΔFosB is suggested as a possible outcome of chronic behaviors, such as addiction. Sleep is discussed as possible mediating factor in the relationship between ΔFosB and chronic alcohol consumption. There were four experimental groups in this study: Control (C), Sleep Deprivation only (SD), Alcohol Exposure only (AO), and both sleep deprivation and alcohol exposure (B). Levels of ΔFosB accumulation in the Nucleus Accumbens (NAc) revealed a significant main effect of sleep deprivation, but no …


Generalization Of Joint Attention: Using Parent Child Interaction Therapy To Program Social Skills In Children With Developmental Disorders, Thomas E. Rigg May 2016

Generalization Of Joint Attention: Using Parent Child Interaction Therapy To Program Social Skills In Children With Developmental Disorders, Thomas E. Rigg

Masters Theses, 2010-2019

Generalization of social behaviors is a vital component of human behavior. Children with Autism Spectrum Disorder often show symptomology that includes impairment in social behavior and failure to generalize behavior on the whole. Initiation of joint attention is a social behavior that can be understood as a behavior cusp and worthy of intervention to promote development. Parent-Child Interaction Therapy has been studied in recent years for its efficacy in treating some dimensions of Autism Spectrum Disorder in children and adolescence. The current study sought to explore the efficacy of Parent-Child Interaction Therapy in promoting the generalization of initiation of joint …


Creative Counseling Techniques For Elementary-Aged Children, Brian C. Caperton May 2016

Creative Counseling Techniques For Elementary-Aged Children, Brian C. Caperton

Educational Specialist, 2009-2019

Research suggests widespread decline of creative ability in elementary-aged children, particularly kindergarten through 3rd grade (Kim, 2012). The increase of mental health disorders in children, the exponential rise of technology use, and the surge of psychotropic medication use indicate the need for nuanced, divergent clinical interventions. Creative counseling fills this demand by offering children opportunities to engage in open-ended, reflective abstraction and other therapeutic processes. The author opens with an overview of creativity and psychology, conceptualizes the target population, and discusses theories, models, and interventions of creative counseling with elementary-aged children. The paper will provide clinicians with an understanding …


Parent-Child Interaction Therapy Informed By Applied Behavior Analysis For Developmental Delay: Parent And Sibling Coaching With Setting Generalization, Mariel S. Cannady May 2016

Parent-Child Interaction Therapy Informed By Applied Behavior Analysis For Developmental Delay: Parent And Sibling Coaching With Setting Generalization, Mariel S. Cannady

Dissertations, 2014-2019

Parent-Child Interaction Therapy (PCIT) is a well-established, empirically-supported treatment for young children with disruptive behaviors. PCIT was initially designed for treatment of typically-developing children with oppositional and disruptive behaviors. There is emerging support for PCIT as a treatment for behavior challenges seen in children with developmental delays. However, some modifications may be needed to respond to the severity of delay, parent treatment goals, and the function of the challenging behavior. Using a non-concurrent multiple-baseline experimental design, the current study examined the effectiveness of a modified PCIT approach for a preschool child with global developmental delay and co-occurring behavior problems. Modifications …


Ventromedial Prefrontal Cortex Damage Is Associated With Decreased Ventral Striatum Volume And Response To Reward, Maia Pujara, Carissa Philippi, Julian Motzkin, Mustafa Baskaya, Michael Koenigs May 2016

Ventromedial Prefrontal Cortex Damage Is Associated With Decreased Ventral Striatum Volume And Response To Reward, Maia Pujara, Carissa Philippi, Julian Motzkin, Mustafa Baskaya, Michael Koenigs

Psychology Faculty Works

The ventral striatum and ventromedial prefrontal cortex (vmPFC) are two central nodes of the “reward circuit” of the brain. Human neuroimaging studies have demonstrated coincident activation and functional connectivity between these brain regions, and animal studies have demonstrated that the vmPFC modulates ventral striatum activity. However, there have been no comparable data in humans to address whether the vmPFC may be critical for the reward-related response properties of the ventral striatum. In this study, we used fMRI in five neurosurgical patients with focal vmPFC lesions to test the hypothesis that the vmPFC is necessary for enhancing ventral striatum responses to …


Touch Screen Technology In The First Three Years, Sara Baumgarten May 2016

Touch Screen Technology In The First Three Years, Sara Baumgarten

Graduate Student Independent Studies

There has long been debate about the use of screen technology with young children. The first part of this paper reviews the literature currently available, looking at previous research about television viewing as well as emerging research about touch screens. The second part takes observation of three toddlers, ages 20-26 months, using iPads as well as playing with traditional toys and analyzes the differences in play and the developmental skills demonstrated by each.


The Enigma Of Sexual Desire, Part 1: A Brief Review Of Classical, Historical, Philosophical, And Literary Perspectives, David L. Rowland May 2016

The Enigma Of Sexual Desire, Part 1: A Brief Review Of Classical, Historical, Philosophical, And Literary Perspectives, David L. Rowland

Psychology Faculty Publications

Throughout human history and across cultures, sexual desire has been of interest to the general public and, now more recently, to the medical/psychological community. Part 1 of this two part series examines the historical aspects of the concept of sexual desire throughout its many transformations, beginning with the writings and mythologies of the ancient Greeks and extending through the ages to the present through the writings of philosophers, playwrights, novelists, and historians. We explore the concept of desire as both a tolerated and celebrated construct over the ages, discussing Western sociocultural perspectives regarding its nature and condition. In our view, …


Occupational Stressors And Health Outcomes For Nurses Working In Correctional Or Non-Correctional Settings, Alyssa R. Zabin May 2016

Occupational Stressors And Health Outcomes For Nurses Working In Correctional Or Non-Correctional Settings, Alyssa R. Zabin

University Scholar Projects

Due to the nature of their work, nurses often face unique occupational stressors and health outcomes. It is important to understand the source of this occupational stress and its affect on health, so that improvements can be made. This study sought to examine occupational stress and health outcomes for both correctional and non-correctional nurses across the continental United States. A survey regarding occupational stressors, community characteristics, individual beliefs, and health outcomes was completed by the nurses (N=459). Predictors including demographic factors, work related stressors, community/network factors, individual beliefs, and health conditions were investigated using linear and Poisson regression …


Effects Of Music On Puzzle Solving, Roberta Kerosevic May 2016

Effects Of Music On Puzzle Solving, Roberta Kerosevic

Undergraduate Psychology Research Methods Journal

The purpose of this study was to see how listening to different genres of music affects performance on puzzle solving, particularly word searches. Students completed puzzles of equal difficulty and under different genres of music and the absence of music. The three genres of music were instrumental and included classical, heavy metal, and pop music. There was also a round where no music was played. Students had four rounds to do four different word searches; each round consisted of a different word search topic and was given to each person in a different order. During each round, all participants listened …


Diagnoses By Gender: The Consequences Of Treatment Of The Mentally Ill In Virginia Woolf's The Waves And Mrs. Dalloway 2016, Erika Nichole Jackson May 2016

Diagnoses By Gender: The Consequences Of Treatment Of The Mentally Ill In Virginia Woolf's The Waves And Mrs. Dalloway 2016, Erika Nichole Jackson

Master's Theses

“Insanity is purely a disease of the brain…The physician is now the responsible guardian of the lunatic, and must ever remain so.” Sir John Charles Bucknill (1897)

Mental illness has consistently been and continues to be a subject that is viewed as taboo by society, especially when it comes to diagnosing a patient. Instead of acknowledging a person’s actions, thoughts, and words, society continually disregards mental illness as something that is negative and to be feared. The fact that this area of medicine can be difficult and distressing makes it all the more important to continue research. It is true …


Efficiency Of The Male Effect With Photostimulated Bucks Does Not Depend On Their Familiarity With Goats, A. L. Muñoz, M. Bedos, R. M. Aroña, J. A. Flores, H. Hernández, C. Moussu, Elodie F. Briefer, P. Chemineau, M. Keller, J. A. Delgadillo May 2016

Efficiency Of The Male Effect With Photostimulated Bucks Does Not Depend On Their Familiarity With Goats, A. L. Muñoz, M. Bedos, R. M. Aroña, J. A. Flores, H. Hernández, C. Moussu, Elodie F. Briefer, P. Chemineau, M. Keller, J. A. Delgadillo

Reproductive Behavior Collection

In ewes, the ovulatory response of females exposed to familiar rams is lower than the response of those exposed to novel ones. In goats, males rendered sexually active by exposure to long days are more efficient to induce ovulation in seasonal anestrous females than untreated males. Two experiments were conducted to determine 1) whether male goats remain familiar to females after 45 days of separation; and 2) whether photostimulated males are able to stimulate the sexual activity of females, independently of their familiarity with them. In Experiment 1, three groups of goats (n = 10 goats per group) were put …


Are Domestic Pigs (Sus Scrofa Domestica) Able To Use Complex Human-Given Cues To Find A Hidden Reward?, Christian Nawroth, Mirjam Ebersbach, Eberhard Von Borell May 2016

Are Domestic Pigs (Sus Scrofa Domestica) Able To Use Complex Human-Given Cues To Find A Hidden Reward?, Christian Nawroth, Mirjam Ebersbach, Eberhard Von Borell

Social Cognition Collection

Understanding human-animal interactions in livestock production systems is crucial for improving animal welfare. It is therefore of general interest to investigate how livestock animals obtain information from humans. By using an object-choice paradigm, we investigated whether domestic pigs (n = 4) are able to use a variety of human-given cues, such as different pointing gestures, to find a hidden food reward. In Experiment 1, an experimenter pointed towards a baited location in front of the pig while the extent of the protrusion of his hand from the upper body was varied. Pigs had problems using pointing gestures that did not …


Interconnections Between Perceptions Of Blame, Mind, And Moral Abilities, Alex Ropes, Steve Guglielmo May 2016

Interconnections Between Perceptions Of Blame, Mind, And Moral Abilities, Alex Ropes, Steve Guglielmo

Psychology Honors Projects

Theories of blame, mind, and moral attribution consider an individual’s perceived agency, operationalized in part as perceived intentionality and self-control. People with autism spectrum disorder (ASD) may display social deficits and a greater tendency to engage in problem behavior (PB; American Psychiatric Association, 2013) than neurotypical (NT) people, which may lead people to perceive that individuals with ASD act less agentically. Study 1 shows that the mitigated perceived agency of people with ASD leads to mitigated blame attribution. In addition to perceived agency, theories of mind and moral attribution account for perceptions of an individual’s capacity to experience emotions, pleasure, …


Suffering In The Human Experience: An Examination Of The Book Of Job And King Lear, Allison Denton May 2016

Suffering In The Human Experience: An Examination Of The Book Of Job And King Lear, Allison Denton

English Department Student Scholarship

This thesis uses the Old Testament figure of Job and the Shakespearean character King Lear to examine how suffering calls us to question life and its meaning. These works were chosen because of their authors' demonstrated value of life despite their protagonists' pain. This project originated from a desire to answer questions about the meaning of life that had arisen during four years of study at the College of the Holy Cross.


2015-2016, Full Issue May 2016

2015-2016, Full Issue

Undergraduate Psychology Research Methods Journal

No abstract provided.


Contingency Management Works, Clients Like It, And It Is Cost-Effective., Kimberly C. Kirby, Lois A Benishek, Mary B Tabit May 2016

Contingency Management Works, Clients Like It, And It Is Cost-Effective., Kimberly C. Kirby, Lois A Benishek, Mary B Tabit

College of Science & Mathematics Departmental Research

No abstract provided.


The History Of The Disease Concept Of Substance Dependency, Brooke A. Lewis May 2016

The History Of The Disease Concept Of Substance Dependency, Brooke A. Lewis

All NMU Master's Theses

The nomenclature used to signify substance dependence has evolved throughout history. Previously, substance dependence was referred to as specific forms of mania, as addiction, and as a habit. The origins of the disease concept of substance dependence have been disputed. Benjamin Rush (1746-1813) and Thomas Trotter (1760-1832) have been credited as being the founders of the movement to acknowledge substance dependence as a disease. Through efforts of scientists of the 19th and 20th centuries, the concept of substance dependence as a disease has become widely accepted by professionals, the medical community, and the government. Significant contributors to this concept include …


The Effects Of Antipsychotic Treatment Upon Nicotine Associative Reward In A Neonatal Quinpirole Model Of Schizophrenia, Adam Ray Denton May 2016

The Effects Of Antipsychotic Treatment Upon Nicotine Associative Reward In A Neonatal Quinpirole Model Of Schizophrenia, Adam Ray Denton

Undergraduate Honors Theses

Research has revealed that schizophrenics are significantly more likely to smoke cigarettes than the general population, and consume nicotine products at a much more prevalent rate. Further exacerbating this issue, it has been previously demonstrated in clinical populations that the type of antipsychotic treatment administered (typical versus atypical) may result in either an increase or a decrease of already heightened smoking behavior within the schizophrenic population. With these clinical issues in mind, the present study sought to examine the effects of antipsychotic treatment upon the associative reward of nicotine within the neonatal quinpirole model of schizophrenia. We found that treatment …


Mindfulness And Mind-Wandering: The Impact Of Brief Interventions On Child Affect, Arousal, And Cognition, Catherine A. Spann May 2016

Mindfulness And Mind-Wandering: The Impact Of Brief Interventions On Child Affect, Arousal, And Cognition, Catherine A. Spann

Psychology Dissertations - Archive

The ability to self-regulate is critical for healthy development and life success. Recent evidence from the field of contemplative science suggests that mindfulness may enhance self-regulation among children and adolescents. It is unclear whether beneficial effects are only realized when practiced over time or if changes can occur within short time frames. This research adds to the growing literature on mindfulness and self-control by testing whether brief mindfulness practice produces changes in self-control compared to similarly restful states. The current study also explored mechanisms by which practicing mindfulness may impact self-control, specifically focusing on positive affect and arousal. A between-subjects, …


Reinstatement Of Second-Order Fear, Matthew Nelson May 2016

Reinstatement Of Second-Order Fear, Matthew Nelson

USC Aiken Psychology Theses

The purpose of this study was to determine if, after conditioning and extinction of a second-order stimulus, reinstatement of extinguished fear could be produced. The findings of Holmes et al. (2014) do not support reinstatement of second-order fear following post-extinction presentation of the unconditioned stimulus (US). The present study provides a second attempt at uncovering reinstatement following extinction of second-order conditioning. Rat subjects were randomly assigned to 5 groups (n=12), which received first- and second-order conditioning with Light and Tone counterbalanced. Responding to the second-order stimulus (S2) was extinguished through S2-alone presentations for all but the control subjects (Group NE-NR). …


Disruptive Behavior Disorders In Childhood And Criminal Justice System Involvement In Adolescence And Emerging Adulthood: Pilot Results Among Puerto Rican Youth, Marjorine Castillo May 2016

Disruptive Behavior Disorders In Childhood And Criminal Justice System Involvement In Adolescence And Emerging Adulthood: Pilot Results Among Puerto Rican Youth, Marjorine Castillo

Theses and Dissertations

The relationship between Disruptive Behavior Disorders (DBD) in childhood and arrest during adolescence and emerging adulthood was explored in a community sample of 162 Puerto Rican children who lived in the South Bronx, NYC when first recruited. Results indicate a significant link between having DBD in childhood and later arrest.