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Articles 1651 - 1680 of 12639
Full-Text Articles in Entire DC Network
Sex Differences In Stress Reactivity, Brain Morphology, And Oxytocin In The Hypothalamus Of The Gray Short-Tailed Opossum (Monodelphis Domestica), Esperanza I. Zacarias, Daniela Rodriguez, Alexandra Chalons, Sasawan Heingraj, Nicole Altamirano, Joseph Rafac, John L. Vandeberg, Mario Gil
Sex Differences In Stress Reactivity, Brain Morphology, And Oxytocin In The Hypothalamus Of The Gray Short-Tailed Opossum (Monodelphis Domestica), Esperanza I. Zacarias, Daniela Rodriguez, Alexandra Chalons, Sasawan Heingraj, Nicole Altamirano, Joseph Rafac, John L. Vandeberg, Mario Gil
Research Colloquium
Understanding the effects of stress on behavior and cognition is important due to its impact on mental health and wellbeing (Schneiderman et al. 2005). Translational animal research can contribute to the development of new treatments that can improve therapeutic outcomes and our understanding of the neurobiology of stress. In the present study, we complement behavioral stress reactivity with immunohistochemical localization of oxytocin in the hypothalamus, a neuropeptide that regulates stress (Neumann & Slattery, 2016). Oxytocin has potential therapeutic use for mental health disorders (Neumann & Slattery, 2016), and the effects of oxytocin seem to be sexually dimorphic (Love, 2018). Using …
The Experience Of Awe In Nature And Its Implications For Sustainability, Ella Shriner
The Experience Of Awe In Nature And Its Implications For Sustainability, Ella Shriner
Independent Study Project (ISP) Collection
Awe is a complex emotion and a relatively new field of psychological study. Previous studies have looked at the benefits of spending time in nature including spurring environmental action, and how awe is felt in nature. In this study, I investigate the connection between these two ideas by addressing the questions of how Awe is experienced in the Northern Rivers region of Australia, and whether small and big moments of awe motivate people to take environmental action and connect them to their community and the natural world. For this study, I conducted 15 interviews, collected 51 surveys, and personally explored …
Environmental Loss, Displacement, And Anxiety In Portugal: Analyzing News Articles To Differentiate Manifestations Of Environmental Distress, Robin Greene
Independent Study Project (ISP) Collection
Expressions of environmental distress can take different forms, with different symptoms, causes, and treatments. Existing literature generally identifies three primary categories of environmental distress responses: environmental grief, solastalgia, and eco-anxiety. This paper explores these distinctions and identifies words typically associated with each category in Portuguese news articles using Latent Dirichlet Allocation (LDA). LDA is a Natural Language Processing (NLP) technique that groups words into topics and identifies connections between those words based on how often those words appear together in sequences. This paper uses a modified LDA algorithm called GuidedLDA to identify additional keywords within topics defined by a list …
Columnas: The Honors Program Newsletter At Bentley University, Hailey Jennato, Samson Shen, Clara Williams
Columnas: The Honors Program Newsletter At Bentley University, Hailey Jennato, Samson Shen, Clara Williams
Honors Program
Page 1: HOW AI IS IMPACTING THE BENTLEY CLASSROOM AND EDUCATION OVERALL ~ by Nayeli Franco ’24
Page 2: A BEAUTY OF DIVERSITY ~ by Yun Song ’26
Page 3: RESURRECTING THE DEAD THROUGH COMPUTER TECHNOLOGY: HONORING THEIR MEMORY OR EXPLOITING THEIR LEGACY? ~ by Hailey Jennato ’24
Page 4: THE IMPORTANCE OF DEVELOPING EMOTIONAL INTELLIGENCE ~ by Isa Ramirez Perdomo ’26
Page 5: FROM STRUGGLE TO STRENGTH: THRIVING AS AN INTERNATIONAL STUDENT ~ by Ledion Hoti ’25
Page 6: CHASING BUTTERFLIES ~ by Alyssa Galin ’27
Disaster Movies And The Perception Of Human Behavior Myths In Disasters, John Carr
Disaster Movies And The Perception Of Human Behavior Myths In Disasters, John Carr
Dissertations
This study explored if disaster movies change the perceptions viewers hold regarding human behavior in disasters, and if so, whether these effects are observable six weeks after watching the disaster movie. The study documented the anticipation of disaster myths in human behavior for 121 respondents, providing data that can better inform the discussion of disaster myths and realities. The study found changes to anticipation of disaster myths in human behavior and realities across multiple categories, with statistically significant results related to the factor of Looting Myth. Limitations for this study include a small sample size, and the external influence of …
Pubertal Progression And Its Relationship To Psychological And Behavioral Outcomes Among Adolescent Boys, Meng-Che Tsai, Yu-Chung Lawrence Wang, Hsun-Yu Chan
Pubertal Progression And Its Relationship To Psychological And Behavioral Outcomes Among Adolescent Boys, Meng-Che Tsai, Yu-Chung Lawrence Wang, Hsun-Yu Chan
Faculty Publications
Variations in pubertal timing and tempo have relevance to psychosocial development. Accounting for pubertal timing, tempo, and psychosocial development simultaneously in a model remains challenging. This study aimed to document the typology of pubertal development in a cohort of Taiwanese adolescent boys and then to examine how the associations between psychosocial variables across time vary by the patterns of pubertal development. A group of adolescent boys (n = 1,368) reported pubertal signs and psychosocial variables for 3 years since seventh grade. The growth mixture model revealed three major classes of pubertal transition: average pubertal growth, late-onset with rapid catch-up, and …
Analyzing Stress Levels Of Volunteers Hand-Rearing Juvenile Spectacled Flying Foxes (Pteropus Conspicillatus) At The Tolga Bat Hospital, North Queensland, Australia, Olivia Knight
Independent Study Project (ISP) Collection
This study, conducted at the Tolga Bat Hospital in North Queensland, Australia, focuses on analyzing the stress levels of volunteers hand-rearing juvenile spectacled flying foxes (Pteropus conspicillatus). Given the endangered status of this species and the intensive care required for their rehabilitation, the research aimed to understand the physical, emotional, and mental well-being of the volunteers engaged in this demanding conservation work. The study was conducted over a five-day period during the peak pupping season in November 2023, utilizing self-administered questionnaires to assess the well-being and stress levels of volunteers both before and after their nursing sessions. The participants, primarily …
Neural Correlates Of Audiovisual Integration, Jonathan Conrady
Neural Correlates Of Audiovisual Integration, Jonathan Conrady
Theses and Dissertations
Successfully integrating multiple streams of information is paired with a variety of behavioral enhancements. Multisensory research over the past few decades has demonstrated the criticality of spatial proximity and stimulus effectiveness. Here, we focused on the temporal aspects and underlying neural activity of frequency-varying, audiovisual stimuli using scalp recorded electroencephalography (EEG). Our set of stimuli was particularly chosen because humans are most sensitive to the auditory sound and visual spatial frequencies that make up speech. Recent work has shown that audiovisual integration effects of low-level, simple stimuli are largest when both modalities fall within, compared to outside of, their respective …
Electrophysiological Responses To Emotional And Cocaine Cues Reveal Individual Neuroaffective Profiles In Cocaine Users, Heather E Webber, Constanza De Dios, Margaret C Wardle, Robert Suchting, Charles E Green, Joy M Schmitz, Scott D Lane, Francesco Versace
Electrophysiological Responses To Emotional And Cocaine Cues Reveal Individual Neuroaffective Profiles In Cocaine Users, Heather E Webber, Constanza De Dios, Margaret C Wardle, Robert Suchting, Charles E Green, Joy M Schmitz, Scott D Lane, Francesco Versace
Faculty, Staff and Student Publications
Smokers with stronger neuroaffective responses to drug-related cues compared to non-drug-related pleasant images (C>P) are more vulnerable to compulsive smoking than individuals with the opposite brain reactivity profile (P>C). However, it is unknown if these neurobehavioral profiles exist in individuals abusing other drugs. We tested whether individuals with cocaine use disorder (CUD) show similar neuroaffective profiles to smokers. We also monitored eye movements to assess attentional bias toward cues and we further performed exploratory analyses on demographics, personality, and drug use between profiles. Participants with CUD (n=43) viewed pleasant, unpleasant, cocaine, and neutral images while we recorded electroencephalogram. …
Beneath The Surface: An Investigation Into The Relation Between Power, Dehumanization, And Objectification In And Initial Social Interaction, Lillian Hefner
Beneath The Surface: An Investigation Into The Relation Between Power, Dehumanization, And Objectification In And Initial Social Interaction, Lillian Hefner
Honors Program: Senior Projects (Public)
Objectification theory suggests that women are disproportionately affected by objectification leading them to experience more negative health outcomes such as depression and eating disorders. Further research on objectification and synthesis of leading theories in the area suggest that power may be one factor likely to predict the objectification and dehumanization of women. One important dimension of this objectification and dehumanization is the environment in which it occurs. Few studies examine a social/dating context as the current study does. We expected the men in the study who felt a stronger sense of power during the interaction would exhibit more objectification of …
Predictors And Moderators Of Treatment Outcomes For Anxious Children Randomized To Computer-Assisted Cognitive Behavioral Therapy Or Standard Community Care, Orri Smárason, Andrew G Guzick, Wayne K Goodman, Alison Salloum, Eric A Storch
Predictors And Moderators Of Treatment Outcomes For Anxious Children Randomized To Computer-Assisted Cognitive Behavioral Therapy Or Standard Community Care, Orri Smárason, Andrew G Guzick, Wayne K Goodman, Alison Salloum, Eric A Storch
Faculty, Staff and Students Publications
Introduction:
Computer-assisted cognitive behavioral therapy (CCBT) for childhood anxiety disorders may aid the dissemination of CBT, while maintaining treatment fidelity. Although CCBT is an effective intervention, not everyone benefits equally from treatment. Identifying patient characteristics that predict who will benefit from treatment and to what extent can help with matching patients to suitable interventions, and allow researchers and clinicians to modify, and individualize, their treatment formats more effectively. Such predictors and moderators have not yet been examined for CCBT outcomes in anxious children and studies of more traditional treatment formats have yielded inconsistent results.
Methods:
Using data from a randomized …
Neuromodulation For Adjunctive Treatment In Postmastectomy Pain Syndrome, Kennedy Kirkpatrick, Jay D Shah, Krishna Shah
Neuromodulation For Adjunctive Treatment In Postmastectomy Pain Syndrome, Kennedy Kirkpatrick, Jay D Shah, Krishna Shah
Faculty, Staff and Students Publications
Postmastectomy pain syndrome (PMPS) affects nearly half of patients who undergo mastectomy to treat breast cancer. As the survival rate of breast cancer increases with advancements in treatment, the incidence of PMPS is also increasing. Patients with PMPS can experience unrelenting, chronic pain refractory to traditional management with oral pharmacotherapy in conjunction with nonpharmacologic treatment (physical therapy, transcutaneous electrical nerve stimulation (TENS)). Neuromodulation is an emerging treatment modality for numerous chronic pain conditions. This case report highlights the tremendous success of spinal cord stimulator placement for a patient with PMPS.
The Impact Of Biological Sex On Motor Function And Responses To Novel Environments In The Gray Short-Tailed Opossum (Monodelphis Domestica), Esperanza I. Alaniz, Ismael Perez, Sasawan Heingraj, Katelynn Renteria, Cristian M. Botello, Joseph C. Cantu, John L. Vandeberg, Mario Gil
The Impact Of Biological Sex On Motor Function And Responses To Novel Environments In The Gray Short-Tailed Opossum (Monodelphis Domestica), Esperanza I. Alaniz, Ismael Perez, Sasawan Heingraj, Katelynn Renteria, Cristian M. Botello, Joseph C. Cantu, John L. Vandeberg, Mario Gil
Research Symposium
Background: Understanding the different stress reactions in different environments can help us understand stress factors. Studying animal behavior is important for translational research for mental health improvement.
Previous literature has shown that stress is a risk factor for higher cancer incidence and poorer cancer survival. (Klejbor & Turlejski., 2012), as well as mental health outcomes. Understanding of how stress is related to cancer can help improve therapeutic outcomes as preventive measures (Glaser et al., 1987).
Methods: Using the Rota Rod apparatus, 12 animals (3 males, 9 females) were tested at 36 rpm for a maximum of 400 seconds (Madroñal et …
From Bench To Bedside: Bridging The Gap Between Animal Behavior Research And The Study Of Human Personality And Psychopathology, William Reckley, Mario Gil
From Bench To Bedside: Bridging The Gap Between Animal Behavior Research And The Study Of Human Personality And Psychopathology, William Reckley, Mario Gil
Research Symposium
Background: Most psychopathology focuses on the current mental picture of an individual with some including relations to the past experience. One problem with the biomedical studies of psychopathologies is the difficulty in using animals to describe and model these mental states in humans. This difficult task has been confounded by the inability to classify animals in a way that will provide general models that will allow better translation to hypotheses in humans. Therefore, the present investigation explores statistical/research strategies to organize variables using lab animals to facilitate the translation of this information to humans.
Methods: Factor analysis/PCA was used to …
A Neurodevelopmental Perspective To Improve Innovation In Preventive Treatment Of Substance Use Disorders, Ismael Perez, John Vandeberg, Mario Gil
A Neurodevelopmental Perspective To Improve Innovation In Preventive Treatment Of Substance Use Disorders, Ismael Perez, John Vandeberg, Mario Gil
Research Symposium
Background: Midbrain dopaminergic neurons have been associated with substance use disorders (Blaess & Ang, 2015). Understanding their neurodevelopment during early stages of life is fundamental for innovating preventive care treatments. The animal model Monodelphis domestica has been proposed as an excellent candidate to study neurodevelopmental changes due to the ease of access to see changes in their embryonic development (Mate et al., 1994). The purpose of our study is to inform how brain cells, including and especially dopaminergic neurons, mature by quantifying their number during early development. Additionally, the study aims to compare different midbrain areas and track neurodevelopmental changes …
The Impact Of Social Isolation On The Neural Pathways Of Dopamine Neurons In The Ventral Tegmental Area (Vta) And The Nucelus Accumbens (Nac): Implications For The Treatment Of Depression, Anxiety, And Drug Addiction., Cristian M. Botello, Sasawan Heingraj, John L. Vandeberg, Mario Gil
The Impact Of Social Isolation On The Neural Pathways Of Dopamine Neurons In The Ventral Tegmental Area (Vta) And The Nucelus Accumbens (Nac): Implications For The Treatment Of Depression, Anxiety, And Drug Addiction., Cristian M. Botello, Sasawan Heingraj, John L. Vandeberg, Mario Gil
Research Symposium
As the literature on the Monodelphis domestica continues to grow, it is important to contribute to the knowledge base regarding neural pathways and their role in social behavior in this species. Previous studies have provided evidence that increased activity in ventral tegmental area (VTA) dopamine neurons were associated with more social activity in mice. It is also known that in traditional rodent models, the Nucleus Accumbens (NAcc) is implicated in interaction reward processes like motivation; however, more research is needed to elucidate the role of the NAcc in social behavior of the M. domestica. The present study was designed …
Mixed Method Approach Towards The Life Of University Students During The Covid-19 Pandemic, Raihan Khan, Andrew White, Tony Jehi
Mixed Method Approach Towards The Life Of University Students During The Covid-19 Pandemic, Raihan Khan, Andrew White, Tony Jehi
Department of Health Sciences - Faculty Scholarship
Background
The COVID-19 pandemic negatively impacted the higher education system. This mixed-methods study aimed to assess COVID-19 fear, anxiety, and stress among Shenandoah Valley college students.
Methods
An online survey was fielded and completed by n=680 students. Qualitative semi-structured interviews were conducted with 20 students.
Results
The mean participant age was 22.14±5.48 years, and primarily White (81.9%), women (80.4%), and undergraduate (78.0%) students. Approximately 41% were enrolled in health-related majors (41.4%). Women students had significantly higher anxiety, depression, and fear of contracting COVID-19 than men. Undergraduate students had significantly higher depression than graduate students. Qualitative analysis revealed several major themes: …
After The Disaster Guidebook: Designing A Post-Disaster Communication Intervention For Rural Landowners, Channing Bice, Susan Carter
After The Disaster Guidebook: Designing A Post-Disaster Communication Intervention For Rural Landowners, Channing Bice, Susan Carter
Journal of Extension
Extension is well-positioned to facilitate communication strategies that foster community resilience and disaster recovery, particularly for rural residents. This paper proposes a new approach to post-disaster communication that strengthens rural community capacities in locally and culturally relevant ways. The findings revealed specific post-disaster information needs, preferences for local resources, and communication that encourages resilience through a document analysis and interviews with informants recovering from the 2020 Colorado wildfires. The practical recommendations discussed serve as a starting point for Extension professionals in other areas to consider ways to engage with their communities before, during, and after a disaster.
The Impact Of The Fall On Behavior, Intellect, And Emotion, Robert Monte Nelson
The Impact Of The Fall On Behavior, Intellect, And Emotion, Robert Monte Nelson
Doctoral Dissertations and Projects
The purpose of this research is to explore theological doctrines surrounding the Fall and to examine the impact of the Fall on human behavior, intellect, and emotion. This research maintains that the Fall of Adam led to the corruption of the volition, intellect, and emotions of Adam and Eve, who were created in the image of a perfect and holy God, without sin, and argues that humanity’s fallen condition impacts human emotions; however, they are distinct from divine emotions and are not an aspect of the imago Dei. Therefore, this dissertation will explore the meaning of the imago Dei, the …
Timeless Mirai Mindfulness: Interview With Ryan Neil
Timeless Mirai Mindfulness: Interview With Ryan Neil
The International Journal of Ecopsychology (IJE)
Inspired by the video: “Mirai in the Wild - Crater Lake” https://vimeo.com/618586806
https://bonsaimirai.com/press
Physical Time Within Human Time
Physical Time Within Human Time
The International Journal of Ecopsychology (IJE)
A possible solution is offered to help resolve the “two times problem” regarding the veridical and illusory nature of time. First it is recognized that the flow (passage) of time is part of a wider array of temporal experiences referred to as manifest time, all of which need to be reconciled. Then, an information gathering and utilizing system (IGUS) model is used as a basis for a view of manifest time. The model IGUS robot of Hartle that solves the “unique present” debate is enhanced with veridical and (corresponding) illusory components of not only the flow of time but also …
Table Of Contents: Foundations Iv--Time
Table Of Contents: Foundations Iv--Time
The International Journal of Ecopsychology (IJE)
No abstract provided.
Editorial Postscript
The International Journal of Ecopsychology (IJE)
No abstract provided.
Theories Of Consciousness And A Life Worth Living, Liad Mudrik, Myrto Mylopoulos, Niccolo Negro, Aaron Schurger
Theories Of Consciousness And A Life Worth Living, Liad Mudrik, Myrto Mylopoulos, Niccolo Negro, Aaron Schurger
Psychology Faculty Articles and Research
What is it that makes a life valuable? A popular view is that life’s moral worth depends in some way on its relationship to consciousness or subjective experience. But a practical application of this view requires the ability to test for consciousness, which is currently lacking. Here, we examine how theories of consciousness (ToCs) can help do so, focusing especially on difficult cases where the answer is not clear (e.g. fetuses, nonhuman animals, unresponsive brain-injured patients, and advanced artificial systems). We consider five major ToCs and what predictions they offer: Integrated information theory, Higher-Order Thought Theory, Recurrent Processing Theory, Global …
Evidence Of Neurovascular Water Exchange And Endothelial Vascular Dysfunction In Schizophrenia: An Exploratory Study, Eric L Goldwaser, Danny J J Wang, Bhim M Adhikari, Joshua Chiappelli, Xingfeng Shao, Jiaao Yu, Tong Lu, Shuo Chen, Wyatt Marshall, Alexa Yuen, Mark Kvarta, Yizhou Ma, Xiaoming Du, Si Gao, Osamah Saeedi, Heather Bruce, Patrick Donnelly, Hugh O'Neill, Alan R Shuldiner, Braxton D Mitchell, Peter Kochunov, L Elliot Hong
Evidence Of Neurovascular Water Exchange And Endothelial Vascular Dysfunction In Schizophrenia: An Exploratory Study, Eric L Goldwaser, Danny J J Wang, Bhim M Adhikari, Joshua Chiappelli, Xingfeng Shao, Jiaao Yu, Tong Lu, Shuo Chen, Wyatt Marshall, Alexa Yuen, Mark Kvarta, Yizhou Ma, Xiaoming Du, Si Gao, Osamah Saeedi, Heather Bruce, Patrick Donnelly, Hugh O'Neill, Alan R Shuldiner, Braxton D Mitchell, Peter Kochunov, L Elliot Hong
Faculty, Staff and Student Publications
BACKGROUND AND HYPOTHESIS: Mounting evidence supports cerebrovascular contributions to schizophrenia spectrum disorder (SSD) but with unknown mechanisms. The blood-brain barrier (BBB) is at the nexus of neural-vascular exchanges, tasked with regulating cerebral homeostasis. BBB abnormalities in SSD, if any, are likely more subtle compared to typical neurological insults and imaging measures that assess large molecule BBB leakage in major neurological events may not be sensitive enough to directly examine BBB abnormalities in SSD.
STUDY DESIGN: We tested the hypothesis that neurovascular water exchange (Kw) measured by non-invasive diffusion-prepared arterial spin label MRI (n = 27 healthy controls [HC], n = …
Multiancestry Analysis Of The Hla Locus In Alzheimer’S And Parkinson’S Diseases Uncovers A Shared Adaptive Immune Response Mediated By Hla-Drb1*04 Subtypes, Yann Le Guen, Guo Luo, Aditya Ambati, Vincent Damotte, Iris Jansen, Eric Yu, Aude Nicolas, Itziar De Rojas, Thiago Peixoto Leal, Akinori Miyashita, Céline Bellenguez, Michelle Mulan Lian, Kayenat Parveen, Takashi Morizono, Hyeonseul Park, Benjamin Grenier-Boley, Tatsuhiko Naito, Fahri Küçükali, Seth D Talyansky, Selina Maria Yogeshwar, Vicente Sempere, Wataru Satake, Victoria Alvarez, Beatrice Arosio, Michael E Belloy, Luisa Benussi, Anne Boland, Barbara Borroni, María J Bullido, Paolo Caffarra, Jordi Clarimon, Antonio Daniele, Daniel Darling, Stéphanie Debette, Jean-François Deleuze, Martin Dichgans, Carole Dufouil, Emmanuel During, Emrah Düzel, Daniela Galimberti, Guillermo Garcia-Ribas, José María García-Alberca, Pablo García-González, Vilmantas Giedraitis, Oliver Goldhardt, Caroline Graff, Edna Grünblatt, Olivier Hanon, Lucrezia Hausner, Stefanie Heilmann-Heimbach, Henne Holstege, Jakub Hort, Yoo Jin Jung, Deckert Jürgen, Silke Kern, Teemu Kuulasmaa, Kun Ho Lee, Ling Lin, Carlo Masullo, Patrizia Mecocci, Shima Mehrabian, Alexandre De Mendonça, Mercè Boada, Pablo Mir, Susanne Moebus, Fermin Moreno, Benedetta Nacmias, Gael Nicolas, Shumpei Niida, Børge G Nordestgaard, Goran Papenberg, Janne Papma, Lucilla Parnetti, Florence Pasquier, Pau Pastor, Oliver Peters, Yolande A L Pijnenburg, Gerard Piñol-Ripoll, Julius Popp, Laura Molina Porcel, Raquel Puerta, Jordi Pérez-Tur, Innocenzo Rainero, Inez Ramakers, Luis M Real, Steffi Riedel-Heller, Eloy Rodriguez-Rodriguez, Owen A Ross, Luis Jose Royo, Dan Rujescu, Nikolaos Scarmeas, Philip Scheltens, Norbert Scherbaum, Anja Schneider, Davide Seripa, Ingmar Skoog, Vincenzo Solfrizzi, Gianfranco Spalletta, Alessio Squassina, John Van Swieten, Raquel Sánchez-Valle, Eng-King Tan, Thomas Tegos, Charlotte Teunissen, Jesper Qvist Thomassen, Lucio Tremolizzo, Martin Vyhnalek, Frans Verhey, Margda Waern, Jens Wiltfang, Jing Zhang, Eadb, Gr@Ace Study Group, Degesco Consortium, Demgene, Eadi, Gerad, Asian Parkinson’S Disease Genetics Consortium, Henrik Zetterberg, Kaj Blennow, Zihuai He, Julie Williams, Philippe Amouyel, Frank Jessen, Patrick G Kehoe, Ole A Andreassen, Cornelia Van Duin, Magda Tsolaki, Pascual Sánchez-Juan, Ruth Frikke-Schmidt, Kristel Sleegers, Tatsushi Toda, Anna Zettergren, Martin Ingelsson, Yukinori Okada, Giacomina Rossi, Mikko Hiltunen, Jungsoo Gim, Kouichi Ozaki, Rebecca Sims, Jia Nee Foo, Wiesje Van Der Flier, Takeshi Ikeuchi, Alfredo Ramirez, Ignacio Mata, Agustín Ruiz, Ziv Gan-Or, Jean-Charles Lambert, Michael D Greicius, Emmanuel Mignot
Multiancestry Analysis Of The Hla Locus In Alzheimer’S And Parkinson’S Diseases Uncovers A Shared Adaptive Immune Response Mediated By Hla-Drb1*04 Subtypes, Yann Le Guen, Guo Luo, Aditya Ambati, Vincent Damotte, Iris Jansen, Eric Yu, Aude Nicolas, Itziar De Rojas, Thiago Peixoto Leal, Akinori Miyashita, Céline Bellenguez, Michelle Mulan Lian, Kayenat Parveen, Takashi Morizono, Hyeonseul Park, Benjamin Grenier-Boley, Tatsuhiko Naito, Fahri Küçükali, Seth D Talyansky, Selina Maria Yogeshwar, Vicente Sempere, Wataru Satake, Victoria Alvarez, Beatrice Arosio, Michael E Belloy, Luisa Benussi, Anne Boland, Barbara Borroni, María J Bullido, Paolo Caffarra, Jordi Clarimon, Antonio Daniele, Daniel Darling, Stéphanie Debette, Jean-François Deleuze, Martin Dichgans, Carole Dufouil, Emmanuel During, Emrah Düzel, Daniela Galimberti, Guillermo Garcia-Ribas, José María García-Alberca, Pablo García-González, Vilmantas Giedraitis, Oliver Goldhardt, Caroline Graff, Edna Grünblatt, Olivier Hanon, Lucrezia Hausner, Stefanie Heilmann-Heimbach, Henne Holstege, Jakub Hort, Yoo Jin Jung, Deckert Jürgen, Silke Kern, Teemu Kuulasmaa, Kun Ho Lee, Ling Lin, Carlo Masullo, Patrizia Mecocci, Shima Mehrabian, Alexandre De Mendonça, Mercè Boada, Pablo Mir, Susanne Moebus, Fermin Moreno, Benedetta Nacmias, Gael Nicolas, Shumpei Niida, Børge G Nordestgaard, Goran Papenberg, Janne Papma, Lucilla Parnetti, Florence Pasquier, Pau Pastor, Oliver Peters, Yolande A L Pijnenburg, Gerard Piñol-Ripoll, Julius Popp, Laura Molina Porcel, Raquel Puerta, Jordi Pérez-Tur, Innocenzo Rainero, Inez Ramakers, Luis M Real, Steffi Riedel-Heller, Eloy Rodriguez-Rodriguez, Owen A Ross, Luis Jose Royo, Dan Rujescu, Nikolaos Scarmeas, Philip Scheltens, Norbert Scherbaum, Anja Schneider, Davide Seripa, Ingmar Skoog, Vincenzo Solfrizzi, Gianfranco Spalletta, Alessio Squassina, John Van Swieten, Raquel Sánchez-Valle, Eng-King Tan, Thomas Tegos, Charlotte Teunissen, Jesper Qvist Thomassen, Lucio Tremolizzo, Martin Vyhnalek, Frans Verhey, Margda Waern, Jens Wiltfang, Jing Zhang, Eadb, Gr@Ace Study Group, Degesco Consortium, Demgene, Eadi, Gerad, Asian Parkinson’S Disease Genetics Consortium, Henrik Zetterberg, Kaj Blennow, Zihuai He, Julie Williams, Philippe Amouyel, Frank Jessen, Patrick G Kehoe, Ole A Andreassen, Cornelia Van Duin, Magda Tsolaki, Pascual Sánchez-Juan, Ruth Frikke-Schmidt, Kristel Sleegers, Tatsushi Toda, Anna Zettergren, Martin Ingelsson, Yukinori Okada, Giacomina Rossi, Mikko Hiltunen, Jungsoo Gim, Kouichi Ozaki, Rebecca Sims, Jia Nee Foo, Wiesje Van Der Flier, Takeshi Ikeuchi, Alfredo Ramirez, Ignacio Mata, Agustín Ruiz, Ziv Gan-Or, Jean-Charles Lambert, Michael D Greicius, Emmanuel Mignot
Faculty, Staff and Students Publications
Across multiancestry groups, we analyzed Human Leukocyte Antigen (HLA) associations in over 176,000 individuals with Parkinson’s disease (PD) and Alzheimer’s disease (AD) versus controls. We demonstrate that the two diseases share the same protective association at the HLA locus. HLA-specific fine-mapping showed that hierarchical protective effects of HLA-DRB1*04 subtypes best accounted for the association, strongest with HLA-DRB1*04:04 and HLA-DRB1*04:07, and intermediary with HLA-DRB1*04:01 and HLA-DRB1*04:03. The same signal was associated with decreased neurofibrillary tangles in postmortem brains and was associated with reduced tau levels in cerebrospinal fluid and to a lower extent with increased Aβ42. …
Wanting Under Surveillance: A Critical Analysis Of Young Women’S Sexual Desire, Jennifer Chmielewski
Wanting Under Surveillance: A Critical Analysis Of Young Women’S Sexual Desire, Jennifer Chmielewski
Dissertations, Theses, and Capstone Projects
The negotiation of sexual desire is argued to be a vital part of the development of women’s sense of agency and well-being. Whereas desire is a concept that is widely used, measured, and diagnosed, women’s experiences of desire are poorly understood. Heeding the calls of feminist psychologists for conceptual analysis, and the need to examine desire within the multiple intimate and sociopolitical contexts in which sexuality develops, my dissertation is a critical feminist analysis of young women’s desire, centered on their subjective and embodied experiences. Moving beyond questions of what women desire or how much desire they have, I explore …
You Hurt My Feelings: Autonomic And Behavioral Responses To Social Exclusion And The Moderating Effect Of Psychopathic Traits, Liat Kofler
Dissertations, Theses, and Capstone Projects
Humans have a fundamental need to form and maintain social connections, and thus experiencing social exclusion is extremely distressing as it threatens this basic human need. Individuals who are socially excluded often respond aggressively, not only towards their ostracizers but also towards innocent bystanders, with ostracism being implicated in extreme acts of violence such as school shootings. However, individual differences in behavior exist within the context of social exclusion as not everyone responds aggressively after being ostracized. Identifying risk factors for retaliatory aggressive behavior following experiences of social exclusion may facilitate the development of targeted interventions aimed at mitigating such …
Attenuated Typicality Effect In Category-Based Inferences: Implications For Autism Spectrum Disorder, Janani Rajagopalan
Attenuated Typicality Effect In Category-Based Inferences: Implications For Autism Spectrum Disorder, Janani Rajagopalan
Dissertations, Theses, and Capstone Projects
Individuals diagnosed with Autism Spectrum Disorder (ASD) often encounter challenges in assimilating atypical exemplars into their categorical prototypes, a cognitive hurdle that can impact their interpretative and integrative capacities. Addressing this problem, the present research sought to develop a robust methodological approach to reduce the effect of this disparity. We examined the elements embedded within the category's internal structure, with the intention of experimentally attenuating the pronounced typicality effect, which is often exaggerated in ASD.
Across four experiments, the thesis investigated the cognitive and neural underpinnings that shape the access to the typicality gradient intrinsic to a category's structure. The …
Confronting The Doppelganger: Mapping The Ontological Terrain Of An Afro-Caribbean Woman As She Rebrands Diasporic, Feminine Identity Politics: An Autoethnography, Aysha E. Todd-Stone
Confronting The Doppelganger: Mapping The Ontological Terrain Of An Afro-Caribbean Woman As She Rebrands Diasporic, Feminine Identity Politics: An Autoethnography, Aysha E. Todd-Stone
Dissertations, Theses, and Capstone Projects
This thesis seeks to interrogate the intricacies governing the intra-racial\ intra-gendered relationship of an Afro-Trinidadian woman as she commandeers professional spaces in North America. The intent is to challenge the instrument of Black sisterhood deeming it as an incomplete, social instrument, and to prove using an auto-ethnographic approach how Diasporic, feminine trauma leads to psychically induced, episodic violence that is highly suggestive but subtle to the naked eye which in turn irretrievably damages intra-interpersonal relations. Quantitative studies have produced a composite from the white\black perspective (Goosby et al., 2015, Sims et al., 2012) and others dealing with gender (Braithwaite., 1981, …