Digital Commons Network^™

Molecular Pathway Reconstruction And Analysis Of Disturbed Gene Expression In Depressed Individuals Who Died By Suicide, Vladimir Zhurov, John D. H. Stead, Zul Merali, Miklos Palkovits, Gabor Faludi, Caroline Schild-Poulter, Hymie Anisman, Michael O. Poulter

Brain and Mind Institute

Molecular mechanisms behind the etiology and pathophysiology of major depressive disorder and suicide remain largely unknown. Recent molecular studies of expression of serotonin, GABA and CRH receptors in various brain regions have demonstrated that molecular factors may contribute to the development of depressive disorder and suicide behaviour. Here, we used microarray analysis to examine the expression of genes in brain tissue (frontopolar cortex) of individuals who had been diagnosed with major depressive disorder and died by suicide, and those who had died suddenly without a history of depression. We analyzed the list of differentially expressed genes using pathway analysis, which …

The Peers Intervention: Social Anxiety, Physiological Regulation, And Core Autistic Symptoms In Adolescents With Autism, Kirsten A. Schohl

Master's Theses (2009 -)

There have been very few effective interventions developed that have focused on improving social skills in adolescents with autism spectrum disorders (ASD), however, the need is persistent. This study aimed to evaluate the effectiveness of the Program for the Enrichment and Education of Relational Skills (PEERS: Laugeson, Frankel, Mogil, & Dillon, 2009). PEERS focuses on improving friendship quality and social skills among adolescents, ages 11-15 years, with higher-functioning ASD. This study included 47 participants, who were randomly assigned to two groups. Assessment measures utilized parent report and adolescent self-report at pre- and post-treatment. In addition, respiratory sinus arrhythmia (RSA) was …

Randomized Clinical Trial Of Cognitive Behavioral Therapy (Cbt) Versus Acceptance And Commitment Therapy (Act) For Mixed Anxiety Disorders, Joanna Arch, Georg Eifert, Carolyn Davies, Jennifer C. Plumb Vilardaga, Raphael D. Rose, Michael G. Craske

Psychology Faculty Articles and Research

Objective—Randomized comparisons of acceptance-based treatments with traditional cognitive behavioral therapy (CBT) for anxiety disorders are lacking. To address this research gap, we compared acceptance and commitment therapy (ACT) to CBT for heterogeneous anxiety disorders.

Method—One hundred twenty eight individuals (52% female, mean age = 38, 33% minority) with one or more DSM-IV anxiety disorders began treatment following randomization to 12 sessions of CBT or ACT; both treatments included behavioral exposure. Assessments at pre-treatment, post-treatment, 6-month, and 12-month follow-up measured anxiety specific (principal disorder Clinical Severity Ratings [CSR], Anxiety Sensitivity Index, Penn State Worry Questionnaire, Fear Questionnaire avoidance) and …

Research Brief: "Web-Based Post-Traumatic Stress Disorder Education For Military Family Members", Institute For Veterans And Military Families At Syracuse University

Institute for Veterans and Military Families

In this study, researchers introduced an educational website to assess and improve knowledge of PTSD, and also help to engage family members in positive actions to assist service members struggling with PTSD. Web-based content can serve as a valuable method of providing care and information to military service members without the risk of being stigmatized; therefore, policy makers should focus on creating and maintaining structural and financial support for programs that provide military service members, and their families, tools to manage post-deployment issues. Future studies should focus on providing an increased range of services for military families using the educational …

Impact Of Sunlight On The Age Of Onset Of Bipolar Disorder, Michael Bauer, Tasha Glenn, Martin Alda, Ole A. Andreassen, Raffaella Ardau, Frank Bellivier, Michael Berk, Thomas D. Bjella, Letizia Bossini, Maria Del Zompo, Seetal Dodd, Andrea Fagiolini, Mark A. Frye, Ana Gonzalez-Pinto, Chantal Henry, Flávio Kapczinkski, Sebastian Kliwicki, Barbara König, Mauricio Kunz, Beny Lafer, Carlos Lopez-Jaramillo, Mirko Manchia, Wendy Marsh, Monica Martinez-Cengotitabengoa, Ingrid Melle, Gunnar Morken, Rodrigo Munoz, Fabiano G. Nery, Claire O'Donovan, Andrea Pfennig, Danilo Quiroz, Natalie Rasgon, Andreas Reif, Janusz Rybakowski, Kemal Sagduyu, Christian Simhandi, Carla Torrent, Eduard Vieta, Mark Zetin, Peter C. Whybrow

Marriage and Family Therapy Faculty Articles and Research

Objective: Although bipolar disorder has high heritability, the onset occurs during several decades of life, suggesting that social and environmental factors may have considerable influence on disease onset. This study examined the association between the age of onset and sunlight at the location of onset.

Method: Data were obtained from 2414 patients with a diagnosis of bipolar I disorder, according to DSM-IV criteria. Data were collected at 24 sites in 13 countries spanning latitudes 6.3 to 63.4 degrees from the equator, including data from both hemispheres. The age of onset and location of onset were obtained retrospectively, from …

Choreography And Performance With Deaf Adults Who Have Mental Illness: Culturally Affirmative Participatory Research, Sondra H. Malling

Creative Arts Therapies Theses

Dance/movement therapy (DMT) techniques—particularly choreography and performance techniques—have not been well-researched with Deaf adults who have mental illness. This study investigated the use of DMT, choreography, and performance techniques with Deaf adults with severe and chronic mental illness through participatory artistic inquiry. Primary research questions addressed pragmatic matters of participatory artistic inquiry: What aesthetic choices will the co-researchers make in the dance-making process? How does the researcher provide structure and incorporate her experience as a choreographer without overshadowing the contributions of the co-researchers? Broader philosophical research questions included: How do choreography and performance techniques impact this population’s well-being? How does …

Spontaneous Brain Activity Relates To Autonomic Arousal, Jin Fan, Pengfei Xu, Nicholas T. Van Dam, Tehila Eilam-Stock, Xiaosi Gu, Yue-Jia Luo, Patrick R. Hof

Publications and Research

Although possible sources and functions of the resting-state networks (RSNs) of the brain have been proposed, most evidence relies on circular logic and reverse inference. We propose that autonomic arousal provides an objective index of psychophysiological states during rest that may also function as a driving source of the activity and connectivity of RSNs. Recording blood oxygenation level-dependent (BOLD) signal using functional magnetic resonance imaging and skin conductance simultaneously during rest in human subjects, we found that the spontaneous fluctuations of BOLD signals in key nodes of RSNs are associated with changes in nonspecific skin conductance response, a sensitive psychophysiological …

Psychosocial Vulnerabilities To Depression After Acute Coronary Syndrome: The Pivotal Role Of Rumination In Predicting And Maintaining Depression, Ellen-Ge Denton, Nina Rieckmann, Karina W. Davidson, William F. Chaplin

Publications and Research

Psychosocial vulnerabilities may predispose individuals to develop depression after a significant life stressor, such as an acute coronary syndrome (ACS).The aims are (1) to examine the interrelations among vulnerabilities, and their relation with changes in depressive symptoms 3 months after ACS, (2) to prospectively assess whether rumination interacts with other vulnerabilities as a predictor of later depressive symptoms, and (3) to examine how these relations differ between post-ACS patients who meet diagnostic criteria for depression at baseline versus patients who do not. Within 1week after hospitalization for ACS, and again after 3 months, 387 patients (41% female, 79.6% white, mean …

Opinion: Bias Is Unavoidable, Lisa Cosgrove

Counseling, School Psychology & Sport Faculty Publication Series

It is part of the human condition to have implicit biases—and remain blissfully ignorant of them. Academic researchers, scientists, and clinicians are no exception; they are as marvelously flawed as everyone else. But it is not the cognitive bias that’s the problem. Rather, the denial that there is a problem is where the issues arise. Indeed, our capacity for self-deception was beautifully captured in the title of a recent book addressing researchers’ self-justificatory strategies, Mistakes Were Made (But Not by Me).

Dance/Movement Therapy And Autism: A Case Study, Katherine Ann Porter

Creative Arts Therapies Theses

This thesis explores the development of the therapeutic relationship with a child with autism through dance/movement therapy. The characteristics of Autism Spectrum Disorder effect social interactions, communication, behavior and interests. This means there is difficulty engaging and maintaining reciprocal social interactions, and trouble with receptive and expressive language. The purpose of this study is to describe how movement mirroring in dance/movement therapy affects the development of the therapeutic relationship with a child with autism, through the analysis of the Ways of Seeing approach.

The data collected in this clinical case study consisted of video tapped sessions and Laban Movement Analysis …

Neural Basis Of The Potentiated Inhibition Of Repeated Haloperidol And Clozapine Treatment On The Phencyclidine-Induced Hyperlocomotion, Changjiu Zhao, Tao Sun, Ming Li

Department of Psychology: Faculty Publications

Clinical observations suggest that antipsychotic effect starts early and increases progressively over time. This time course of antipsychotic effect can be captured in a rat phencyclidine (PCP)-induced hyperlocomotion model, as repeated antipsychotic treatment progressively increases its inhibition of the repeated PCP-induced hyperlocomotion. Although the neural basis of acute antipsychotic action has been studied extensively, the system that mediates the potentiated effect of repeated antipsychotic treatment has not been elucidated. In the present study, we investigated the neuroanatomical basis of the potentiated action of haloperidol (HAL) and clozapine (CLZ) treatment in the repeated PCP-induced hyperlocomotion. Once daily for five consecutive days, …

Sleep Hygiene And Problem Behaviors In Snoring And Non- Snoring School-Age Children, Lisa A. Witcher, David Gozal, Dennis L. Molfese, Scott M. Salathe, Karen Spruyt, Valerie Mclaughlin Crabtree

Center for Brain, Biology, and Behavior: Faculty Publications

Objectives—The effects of sleep-disordered breathing, sleep restriction, dyssomnias, and parasomnias on daytime behavior in children have been previously assessed. However, the potential relationship(s) between sleep hygiene and children’s daytime behavior remain to be explored. The primary goal of this study was to investigate the relationship between sleep hygiene and problematic behaviors in non-snoring and habitually snoring children.

Methods—Parents of 100 5- to 8-year-old children who were reported to snore “frequently” to “almost always,” and of 71 age-, gender-, and ethnicity-matched children who were reported to never snore participated in this study. As part of a larger, ongoing study, …

Examining The Association Between Psychiatric Illness And Suicidal Ideation In A Sample Of Treatment-Seeking Canadian Peacekeeping And Combat Veterans With Posttraumatic Stress Disorder, Don Richardson, Kate St. Cyr, Alexandra M. Mcintyre-Smith, David Haslam, Jon D. Elhai, Jitender Sareen

MacDonald Franklin OSI Research Centre

Objective:

Our study examines the association between suicidal ideation and and self-reported symptoms of posttraumatic stress disorder (PTSD), major depressive disorder (MDD), generalized anxiety disorder (GAD), and alcohol use disorder (AUD) in a sample of treatment-seeking Canadian combat and peacekeeping veterans; and identifies potential predictors of suicidal ideation.

Methods:

Actively serving Canadian Forces and Royal Canadian Mounted Police members and veterans seeking treatment at the Parkwood Hospital Operational Stress Injury Clinic (n = 250) completed measures including the Primary Care Evaluation of Mental Disorders Patient Health Questionnaire, the Alcohol Use Disorder Identification Test, and the PTSD Checklist—Military Version (PCL-M) …

Neural Mechanisms Of Decision Making In Hoarding Disorder, David F. Tolin, Michael C. Stevens, Anna L. Villavicencio, Melissa M. Norberg, Vince D. Calhoun, Randy O. Frost, Gail Steketee, Scott L. Rauch, Godfrey D. Pearlson

Psychology: Faculty Publications

Context: Hoarding disorder (HD), previously considered a subtype of obsessive-compulsive disorder (OCD), has been proposed as a unique diagnostic entity in DSM-5. Current models of HD emphasize problems of decision-making, attachment to possessions, and poor insight, whereas previous neuroimaging studies have suggested abnormalities in frontal brain regions. Objective: To examine the neural mechanisms of impaired decision making in HD in patients with well-defined primary HD compared with patients with OCD and healthy control subjects (HCs). Design: We compared neural activity among patients with HD, patients with OCD, and HCs during decisions to keep or discard personal possessions and control possessions …

A Test Of A Conceptual Model Of Sexual Self-Concept And Its Relation To Other Dimensions Of Sexuality, Arielle R. Deutsch

Department of Psychology: Dissertations, Theses, and Student Research

One theoretical concept that has received modest attention in contemporary sexuality research is the sexual self, particularly focusing on sexual self-concept (SSC). While research on the sexual self has expanded over the past 20 years, there is a lack of cohesion within this research that has culminated in a collection of SSC models that, while sharing certain factors, are dissimilar from each other. Therefore a unified conceptual model of SSC needs to be empirically established. Additionally, little research has examined potential differences between genders in how SSC is expressed, as most SSC research focuses exclusively on women. Finally, understanding of …

Making A Large Class Feel Small Using Social Psychology: Introducing Teams To Improve Performance And Learning In A Large-Enrollment Course, Bethany Johnson

Department of Psychology: Dissertations, Theses, and Student Research

Large-enrollment lecture-based classes are increasingly common in higher education. As an alternative approach, active learning methods are meant to develop academic skills and improve understanding of course content. Group work is an effective form of active learning, but students typically despise it. Social psychological small group theory can inform teachers about the characteristics of small groups that influence their capability to improve learning, so that teachers can design more effectual group work for their classes. This study examined what effect introducing permanent teams into a large enrollment class had on students’ sense of classroom community and their learning outcomes, using …

Construct And Criterion Validity Of The Rey Auditory Verbal Learning Test-Spanish Version In Adults With Traumatic Brain Injury, Cristobal Neblina

UNLV Theses, Dissertations, Professional Papers, and Capstones

The Rey Auditory Verbal Learning Test (RAVLT) is among the most commonly used English-language neuropsychological tests of verbal learning and memory. Previous research supports the validity and clinical utility of adaptations of the RAVLT into many diverse languages. In the United States, Hispanics represent the largest and fastest-growing ethnic minority group. As the Hispanic populace continues to grow, so does the need for empirically validated Spanish-language neuropsychological measures. In 2002, a Spanish adaptation of the RAVLT was developed in Puerto Rico (Acevedo-Vargas, 2002). However, validation studies have not been undertaken with clinical samples, and little is known regarding its psychometric …

Affect Identification And Interpersonal Skills: An In-Depth Evaluation Of Social Cognition In Schizophrenia, Griffin Pollock Sutton

UNLV Theses, Dissertations, Professional Papers, and Capstones

The presence of deficits in various sub-domains of social cognition has been investigated to a degree in individuals with schizophrenia. Some of the most commonly researched and documented deficits have included impairments in the identification of affect portrayed in faces. Research has indicated that the performance of individuals with schizophrenia on such tasks is generally impaired as compared to normal controls. However, some have questioned the generalizability of such findings to real-world situations, as day-to-day interactions generally necessitate a constant, fluid assessment of the thoughts and feelings of others and are rarely, if ever, limited to still images of others. …

Hcv Behavioral Health Preparation Of The Racial/Ethnic Minority: Measurement Development Of A Hcv Treatment Readiness Tool In Spanish And English, Michele Vella, Joseph L. Yozviak Do, Facp, Judith Lash Rn

Department of Medicine

No abstract provided.

Parametric Studies Of Antipsychotic-Induced Sensitization In The Conditioned Avoidance Response Model: Roles Of Number Of Drug Exposure, Drug Dose, And Test–Retest Interval, Natashia Swalve, Ming Li

Department of Psychology: Faculty Publications

Repeated haloperidol and olanzapine treatment produces an enhanced disruption of avoidance responding, a validated measure of antipsychotic activity. Experimental parameters affecting this sensitization-like effect have not been thoroughly examined. The present study investigated the role of three parameters (number of injections, dose, and interval between initial exposure and challenge) in antipsychotic sensitization in the conditioned avoidance response paradigm. Well-trained Sprague–Dawley rats received different numbers of drug treatment (1–5 days) or different doses of haloperidol (0.025–0.10 mg/kg, subcutaneously) or olanzapine (0.5–2.0 mg/kg, subcutaneously). After certain time intervals (4, 10 or 17 days), they were tested for the expression of haloperidol or …

Predicting Exercise Adherence In College Students Using A Self-Determination Theory Framework, Megan M. Clarke

Master's Theses

College is a pivotal time for weight gain and unhealthy behavior changes in many young adults. Decreases in physical activity are common in this age group and likely contribute to the 1.6 to 1.8 kg weight gain that is often observed in the first year of college. Identifying groups of students who are at high-risk for decreasing or discontinuing physical activity may help develop more targeted interventions. The present study explored physical activity patterns in the first semester of college and examined predictors of exercise decreases to levels below recommended daily values within a Self-Determination Theory framework. Incoming freshman (n=174; …

Research Brief: "Civilian Employment Among Recently Returning Afghanistan And Iraq National Guard Veterans", Institute For Veterans And Military Families At Syracuse University

Institute for Veterans and Military Families

This brief shows the impact of OIF and OEF National Guard and Reserve veterans' mental health problems on their likelihood of employment. This study, unusually, found that less than half of the surveyed National Guard and Reserve service members had obtained employment by 45-60 days post-mobilization, despite their possible mental health problems. Suggestions for future research include gathering information from all potential survey participants, as well as service members entering the civilian workforce, beyond the first 45-60 days post-deactivation, rather than within this period.

Research Brief: "Protective Factors And Risk Modification Of Violence In Iraq And Afghanistan War Veterans", Institute For Veterans And Military Families At Syracuse University

Institute for Veterans and Military Families

This research studies non-combat related aggressive behavior in service members and the influence of protective factors. Veterans with protective factors, such as having positive social support, are less likely to engage in violence, and therefore expanding social support programs are beneficial. Future research should consider exploring various components of work life in relation to potential aggression.

Primary Care Behavioral Health Consultation Reduces Depression Levels Among Mood-Disordered Patients, Bill Mcfeature, Thomas W. Pierce

Journal of Health Disparities Research and Practice

The purpose of this study was to examine the effects of behavioral health consultative services on levels of depressive symptoms in patients diagnosed with a mood disorder. Two-hundred fifty-one patients with a form of mood disorder completed the PHQ-9 screening tool for depression both before and after a treatment period lasting an average of three months, during which patients received behavioral health consultation services. Results showed that 49.8% of patients participating in this integrated behavioral health care program experienced improvements of at least 50% in PHQ-9 scores from pre- to post-test. Improvements in PHQ-9 scores of at least a five …

Transformation Of Stimulus Function Through Relational Networks: The Impact Of Derived Stimulus Relations On Stimulus Control Of Behavior, Samantha Rose Florentino

USF Tampa Graduate Theses and Dissertations

Relational Frame Theory research involves either of two protocols utilized to establish relational networks and functions for stimuli in those relational networks. Years of research indicate the most prevalent method involves first establishing a relational frame, conditioning one of the stimuli to acquire a particular function, and then providing a test to see if the function trained to one of the stimuli in the network transferred through the relational network to other stimuli. The less common method involves first training a particular function for a stimulus, entering that stimulus in a relational network with at least two other stimuli, and …

Psychotherapy Clients’ Online Behavior And Opinions Regarding Internet Searches Conducted By Therapists, Emily B. Gale

Department of Psychology: Dissertations, Theses, and Student Research

The Internet has become possibly the most popular medium to find information and communicate in our society. For the field of psychology, the Internet offers a new way to collect data and communicate with both study participants and, for practicing psychologists, possibly clients. Little is known, however, about the implications of interacting with clients online. The existing empirical studies in this area (DiLillo & Gale, 2011; Lehavot, Barnett, & Powers, 2010; Taylor et al., 2010) have focused on psychology graduate students’ actions online. These studies highlight the importance and paucity of research regarding the online behaviors of psychotherapy clients and …

Measurement Of A Model Of Implementation For Health Care: Toward A Testable Theory, Joan M. Cook, Casey O'Donnell, Stephanie Dinnen, James C. Coyne, Josef I. Ruzek, Paula P. Schnurr

Dartmouth Scholarship

Greenhalgh et al. used a considerable evidence-base to develop a comprehensive model of implementation of innovations in healthcare organizations [1]. However, these authors did not fully operationalize their model, making it difficult to test formally. The present paper represents a first step in operationalizing Greenhalgh et al.'s model by providing background, rationale, working definitions, and measurement of key constructs.A systematic review of the literature was conducted for key words representing 53 separate sub-constructs from six of the model's broad constructs. Using an iterative process, we reviewed existing measures and utilized or adapted items. Where no one measure was deemed appropriate, …

Rxp Project: Prescription Privileges For Psychologists: Perceptions, Knowledge And Attitude Change Of Oregon Psychologists, Jenna D. Johnson, Amber Hay, Allyna Murray, Jessica C. Lucas, Tanya Tompkins

2012 Projects

The Keck Summer Collaborative Research Program provides opportunities for Linfield College students and faculty to conduct research on issues related to the Pacific Northwest, and to bring the research findings back into the classroom within the subsequent academic year. Students partner with faculty to conduct research and present their work to other students, Linfield staff and faculty, and community members during a series of brown bag lunches. Jenna Johnson, Amber Hay, Allyna Murray, and Jessica Lucas conducted research with Tanya Tompkins and gave this presentation during the summer of 2012.

Over the past two decades, an important, and at times …

Effects Of Gender Composition Of Target And Sender Dyads On The Tendency To Infer Lies, Byron J. Simoneaux

Doctoral Dissertations

Lying is so common in human behavior that some have labeled it a social skill. Despite the ubiquity of lies, humans have consistently been found to be poor lie detectors. Attempts have been made to improve the accuracy of human lie detection. Unfortunately, the most successful training only improves accuracy slightly above the level of chance. Because of its importance to society, considerable effort has been aimed at developing methods to help determine when people are lying. Researching how and why humans infer that another person is lying has the potential to advance the understanding of lie detection. Researchers have …

Traumatic Injury And Identity: Incorporating Traumatic Episodes Into The Life Story, Abbey K. Valvano

Dissertations (1934 -)

With an increasing number of traumatic injury survivors, a better understanding of post-trauma meaning-making processes is needed, including improvement in our understanding of post-trauma narrative reconstruction. This project aimed to identify emergent themes within the life story narratives of spinal cord injured veterans and to both generate and test hypotheses regarding how emergent themes related to an indicator of post-trauma wellness. Seven themes were revealed within two specific sections of the life story interview. Findings revealed that individuals who author their life narratives in such a way as to demonstrate altruism and generativity showed significantly higher wellness. Further, narratives with …